Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_K10
(583 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P35558|PPCKC_HUMAN Phosphoenolpyruvate carboxykinase, cy... 263 2e-70
sp|Q5R5J1|PPCKC_PONPY Phosphoenolpyruvate carboxykinase, cy... 263 2e-70
sp|Q05893|PPCK_ASCSU Phosphoenolpyruvate carboxykinase [GTP... 260 2e-69
sp|Q9Z2V4|PPCKC_MOUSE Phosphoenolpyruvate carboxykinase, cy... 259 3e-69
sp|P05153|PPCKC_CHICK Phosphoenolpyruvate carboxykinase, cy... 259 3e-69
sp|Q8HYZ4|PPCKC_BOVIN Phosphoenolpyruvate carboxykinase, cy... 258 6e-69
sp|P07379|PPCKC_RAT Phosphoenolpyruvate carboxykinase, cyto... 258 8e-69
sp|P29190|PPCK_HAECO Phosphoenolpyruvate carboxykinase [GTP... 248 6e-66
sp|Q8BH04|PPCKM_MOUSE Phosphoenolpyruvate carboxykinase, mi... 246 4e-65
sp|Q16822|PPCKM_HUMAN Phosphoenolpyruvate carboxykinase, mi... 240 2e-63
>sp|P35558|PPCKC_HUMAN Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-C)
Length = 622
Score = 263 bits (672), Expect = 2e-70
Identities = 119/173 (68%), Positives = 140/173 (80%)
Frame = +2
Query: 5 FVKCVHSVGCPRPHPRKVINHWPCNPEKTLIAHLPDERXXXXXXXXXXXXXXXXKKCFAL 184
FVKC+HSVGCP P + ++N+WPCNPE TLIAHLPD R KKCFAL
Sbjct: 189 FVKCLHSVGCPLPLQKPLVNNWPCNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFAL 248
Query: 185 RIAGRIAYDEGWMAEHMLIMSVTNPKGEEKYIAAAFPSACGKTNMAMLEPSLPGWKVQVV 364
R+A R+A +EGW+AEHMLI+ +TNP+GE+KY+AAAFPSACGKTN+AM+ PSLPGWKV+ V
Sbjct: 249 RMASRLAKEEGWLAEHMLILGITNPEGEKKYLAAAFPSACGKTNLAMMNPSLPGWKVECV 308
Query: 365 GDDIAWMRFDEHGELRAINPEAGFFGVAPGTNYKTNPNAMKTFQKNSIFTNVA 523
GDDIAWM+FD G LRAINPE GFFGVAPGT+ KTNPNA+KT QKN+IFTNVA
Sbjct: 309 GDDIAWMKFDAQGHLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVA 361
>sp|Q5R5J1|PPCKC_PONPY Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-C)
Length = 622
Score = 263 bits (672), Expect = 2e-70
Identities = 119/173 (68%), Positives = 140/173 (80%)
Frame = +2
Query: 5 FVKCVHSVGCPRPHPRKVINHWPCNPEKTLIAHLPDERXXXXXXXXXXXXXXXXKKCFAL 184
FVKC+HSVGCP P + ++N+WPCNPE TLIAHLPD R KKCFAL
Sbjct: 189 FVKCLHSVGCPLPLQKPLVNNWPCNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFAL 248
Query: 185 RIAGRIAYDEGWMAEHMLIMSVTNPKGEEKYIAAAFPSACGKTNMAMLEPSLPGWKVQVV 364
R+A R+A +EGW+AEHMLI+ +TNP+GE+KY+AAAFPSACGKTN+AM+ PSLPGWKV+ V
Sbjct: 249 RMASRLAKEEGWLAEHMLILGITNPEGEKKYLAAAFPSACGKTNLAMMNPSLPGWKVECV 308
Query: 365 GDDIAWMRFDEHGELRAINPEAGFFGVAPGTNYKTNPNAMKTFQKNSIFTNVA 523
GDDIAWM+FD G LRAINPE GFFGVAPGT+ KTNPNA+KT QKN+IFTNVA
Sbjct: 309 GDDIAWMKFDAQGHLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVA 361
>sp|Q05893|PPCK_ASCSU Phosphoenolpyruvate carboxykinase [GTP] (Phosphoenolpyruvate
carboxylase) (PEPCK)
Length = 643
Score = 260 bits (665), Expect = 2e-69
Identities = 121/173 (69%), Positives = 139/173 (80%)
Frame = +2
Query: 5 FVKCVHSVGCPRPHPRKVINHWPCNPEKTLIAHLPDERXXXXXXXXXXXXXXXXKKCFAL 184
FV+CVHSVG P+P KVINHWPCNPEKT+IAH P ER KKCFAL
Sbjct: 207 FVRCVHSVGQPKPVATKVINHWPCNPEKTIIAHRPAEREIWSFGSGYGGNSLLGKKCFAL 266
Query: 185 RIAGRIAYDEGWMAEHMLIMSVTNPKGEEKYIAAAFPSACGKTNMAMLEPSLPGWKVQVV 364
RIA I YDEGWMAEHMLIM VT+PKGEE+++AAAFPSACGKTN+AMLEP++PGWKV+V+
Sbjct: 267 RIAMNIGYDEGWMAEHMLIMGVTSPKGEERFVAAAFPSACGKTNLAMLEPTIPGWKVRVI 326
Query: 365 GDDIAWMRFDEHGELRAINPEAGFFGVAPGTNYKTNPNAMKTFQKNSIFTNVA 523
GDDIAWM+F G L AINPE GFFGVAPGT++KTNP AM +FQ+N+IFTNVA
Sbjct: 327 GDDIAWMKFGADGRLYAINPEYGFFGVAPGTSHKTNPMAMASFQENTIFTNVA 379
Score = 30.4 bits (67), Expect = 3.3
Identities = 11/15 (73%), Positives = 13/15 (86%)
Frame = +1
Query: 526 TSDGSYYWEGLEDEV 570
T+DG Y+WEGLE EV
Sbjct: 381 TADGEYFWEGLEHEV 395
>sp|Q9Z2V4|PPCKC_MOUSE Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-C)
Length = 622
Score = 259 bits (662), Expect = 3e-69
Identities = 117/173 (67%), Positives = 139/173 (80%)
Frame = +2
Query: 5 FVKCVHSVGCPRPHPRKVINHWPCNPEKTLIAHLPDERXXXXXXXXXXXXXXXXKKCFAL 184
F+KC+HSVGCP P + ++N+W CNPE TLIAHLPD R KKCFAL
Sbjct: 189 FIKCLHSVGCPLPLKKPLVNNWACNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFAL 248
Query: 185 RIAGRIAYDEGWMAEHMLIMSVTNPKGEEKYIAAAFPSACGKTNMAMLEPSLPGWKVQVV 364
RIA R+A +EGW+AEHMLI+ +TNP+G++KY+AAAFPSACGKTN+AM+ PSLPGWKV+ V
Sbjct: 249 RIASRLAKEEGWLAEHMLILGITNPEGKKKYLAAAFPSACGKTNLAMMNPSLPGWKVECV 308
Query: 365 GDDIAWMRFDEHGELRAINPEAGFFGVAPGTNYKTNPNAMKTFQKNSIFTNVA 523
GDDIAWM+FD G LRAINPE GFFGVAPGT+ KTNPNA+KT QKN+IFTNVA
Sbjct: 309 GDDIAWMKFDAQGNLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVA 361
>sp|P05153|PPCKC_CHICK Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-C)
Length = 622
Score = 259 bits (662), Expect = 3e-69
Identities = 120/173 (69%), Positives = 137/173 (79%)
Frame = +2
Query: 5 FVKCVHSVGCPRPHPRKVINHWPCNPEKTLIAHLPDERXXXXXXXXXXXXXXXXKKCFAL 184
FVKC+HSVGCP P +IN+WPCNPE TLIAHLPD R KKCFAL
Sbjct: 189 FVKCLHSVGCPLPLKEPLINNWPCNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFAL 248
Query: 185 RIAGRIAYDEGWMAEHMLIMSVTNPKGEEKYIAAAFPSACGKTNMAMLEPSLPGWKVQVV 364
RIA RIA +EGW+AEHMLI+ +TNP+GE+KY AAAFPSACGKTN+AM+ PS PGWK++ V
Sbjct: 249 RIASRIAKEEGWLAEHMLILGITNPEGEKKYFAAAFPSACGKTNLAMMNPSRPGWKIECV 308
Query: 365 GDDIAWMRFDEHGELRAINPEAGFFGVAPGTNYKTNPNAMKTFQKNSIFTNVA 523
GDDIAWM+FDE G LRAINPE GFFGVAPGT+ KTNPNA+KT KN+IFTNVA
Sbjct: 309 GDDIAWMKFDELGNLRAINPENGFFGVAPGTSIKTNPNAIKTIFKNTIFTNVA 361
>sp|Q8HYZ4|PPCKC_BOVIN Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-C)
Length = 622
Score = 258 bits (660), Expect = 6e-69
Identities = 116/173 (67%), Positives = 139/173 (80%)
Frame = +2
Query: 5 FVKCVHSVGCPRPHPRKVINHWPCNPEKTLIAHLPDERXXXXXXXXXXXXXXXXKKCFAL 184
FVKC+HSVGCP P + ++N+W CNPE TLIAHLPD R KKCFAL
Sbjct: 189 FVKCLHSVGCPLPLKKPLVNNWACNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFAL 248
Query: 185 RIAGRIAYDEGWMAEHMLIMSVTNPKGEEKYIAAAFPSACGKTNMAMLEPSLPGWKVQVV 364
R+A R+A +EGW+AEHMLI+ +TNPKG++KY AAAFPSACGKTN+AM+ P+LPGWKV+ V
Sbjct: 249 RMASRLAKEEGWLAEHMLILGITNPKGQKKYFAAAFPSACGKTNLAMMNPTLPGWKVECV 308
Query: 365 GDDIAWMRFDEHGELRAINPEAGFFGVAPGTNYKTNPNAMKTFQKNSIFTNVA 523
GDDIAWM+FD+ G LRAINPE GFFGVAPGT+ +TNPNA+KT QKN+IFTNVA
Sbjct: 309 GDDIAWMKFDQQGNLRAINPENGFFGVAPGTSVRTNPNAIKTIQKNTIFTNVA 361
>sp|P07379|PPCKC_RAT Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-C)
Length = 622
Score = 258 bits (659), Expect = 8e-69
Identities = 116/173 (67%), Positives = 139/173 (80%)
Frame = +2
Query: 5 FVKCVHSVGCPRPHPRKVINHWPCNPEKTLIAHLPDERXXXXXXXXXXXXXXXXKKCFAL 184
F+KC+HSVGCP P + ++N+W CNPE TLIAHLPD R KKCFAL
Sbjct: 189 FIKCLHSVGCPLPLKKPLVNNWACNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFAL 248
Query: 185 RIAGRIAYDEGWMAEHMLIMSVTNPKGEEKYIAAAFPSACGKTNMAMLEPSLPGWKVQVV 364
RIA R+A +EGW+AEHMLI+ +TNP+G++KY+AAAFPSACGKTN+AM+ P+LPGWKV+ V
Sbjct: 249 RIASRLAKEEGWLAEHMLILGITNPEGKKKYLAAAFPSACGKTNLAMMNPTLPGWKVECV 308
Query: 365 GDDIAWMRFDEHGELRAINPEAGFFGVAPGTNYKTNPNAMKTFQKNSIFTNVA 523
GDDIAWM+FD G LRAINPE GFFGVAPGT+ KTNPNA+KT QKN+IFTNVA
Sbjct: 309 GDDIAWMKFDAQGNLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVA 361
>sp|P29190|PPCK_HAECO Phosphoenolpyruvate carboxykinase [GTP] (Phosphoenolpyruvate
carboxylase) (PEPCK)
Length = 619
Score = 248 bits (634), Expect = 6e-66
Identities = 119/172 (69%), Positives = 132/172 (76%)
Frame = +2
Query: 5 FVKCVHSVGCPRPHPRKVINHWPCNPEKTLIAHLPDERXXXXXXXXXXXXXXXXKKCFAL 184
FV+C+HSVG PRP ++VINHWPCNPE+ LIAH P ER KK AL
Sbjct: 184 FVRCIHSVGLPRPVKQRVINHWPCNPERVLIAHRPAEREIWSFGSGYGGNSLLGKKMLAL 243
Query: 185 RIAGRIAYDEGWMAEHMLIMSVTNPKGEEKYIAAAFPSACGKTNMAMLEPSLPGWKVQVV 364
RIA IA DEGWMAEHMLIM VT P G+E +IAAAFPSACGKTN+AMLEP+LPGWKV+ V
Sbjct: 244 RIASNIAKDEGWMAEHMLIMGVTRPDGKEHFIAAAFPSACGKTNLAMLEPALPGWKVRCV 303
Query: 365 GDDIAWMRFDEHGELRAINPEAGFFGVAPGTNYKTNPNAMKTFQKNSIFTNV 520
GDDIAWM+F E G L AINPE GFFGVAPGT+ KTNP A+ TFQKNSIFTNV
Sbjct: 304 GDDIAWMKFGEDGRLYAINPEYGFFGVAPGTSKKTNPMAVATFQKNSIFTNV 355
Score = 33.1 bits (74), Expect = 0.52
Identities = 13/20 (65%), Positives = 18/20 (90%), Gaps = 1/20 (5%)
Frame = +1
Query: 526 TSDGSYYWEGLEDEV-DKNL 582
T++G Y+WEGLEDE+ DKN+
Sbjct: 358 TANGEYFWEGLEDEIKDKNV 377
>sp|Q8BH04|PPCKM_MOUSE Phosphoenolpyruvate carboxykinase, mitochondrial precursor [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-M)
Length = 640
Score = 246 bits (627), Expect = 4e-65
Identities = 116/204 (56%), Positives = 140/204 (68%), Gaps = 18/204 (8%)
Frame = +2
Query: 5 FVKCVHSVGCPRPHPRKVINHWPCNPEKTLIAHLPDERXXXXXXXXXXXXXXXXKKCFAL 184
F+KC+HSVG P + WPCNPEKTLI H+PD+R KKCFAL
Sbjct: 207 FIKCLHSVGQPLTGHGDPVGQWPCNPEKTLIGHVPDQREIVSFGSGYGGNSLLGKKCFAL 266
Query: 185 RIAGRIAYDEGWMAEHMLIMSVTNPKGEEKYIAAAFPSACGKTNMAMLEPSLPGWKVQVV 364
RIA R+A DEGW+AEHMLI+ +TNP G+++Y+AAAFPSACGKTN+AM+ P+LPGWKV+ V
Sbjct: 267 RIASRLARDEGWLAEHMLILGITNPAGKKRYVAAAFPSACGKTNLAMMRPALPGWKVECV 326
Query: 365 GDDIAWMRFDEHGELRAINPEAGFFGVAPGTNYKTNPNAMKTFQKNSIFTNVA------- 523
GDDIAWMRFD G+LRAINPE GFFGVAPGT+ TNPNAM T Q N++FTNVA
Sbjct: 327 GDDIAWMRFDSEGQLRAINPENGFFGVAPGTSAATNPNAMATIQSNTLFTNVAETSDGGV 386
Query: 524 -----------GLVMVAITGKDWK 562
G+ + + GK WK
Sbjct: 387 YWEGIDQPLPPGVTITSWLGKPWK 410
>sp|Q16822|PPCKM_HUMAN Phosphoenolpyruvate carboxykinase, mitochondrial precursor [GTP]
(Phosphoenolpyruvate carboxylase) (PEPCK-M)
Length = 640
Score = 240 bits (612), Expect = 2e-63
Identities = 116/204 (56%), Positives = 138/204 (67%), Gaps = 18/204 (8%)
Frame = +2
Query: 5 FVKCVHSVGCPRPHPRKVINHWPCNPEKTLIAHLPDERXXXXXXXXXXXXXXXXKKCFAL 184
FVKC+HSVG P + ++ WPCNPEKTLI H+PD+R KKCFAL
Sbjct: 207 FVKCLHSVGQPLTGQGEPVSQWPCNPEKTLIGHVPDQREIISFGSGYGGNSLLGKKCFAL 266
Query: 185 RIAGRIAYDEGWMAEHMLIMSVTNPKGEEKYIAAAFPSACGKTNMAMLEPSLPGWKVQVV 364
RIA R+A DEGW+AEHMLI+ +T+P G++ AAAFPSACGKTN+AM+ P+LPGWKV+ V
Sbjct: 267 RIASRLARDEGWLAEHMLILGITSPAGKKALCAAAFPSACGKTNLAMMRPALPGWKVECV 326
Query: 365 GDDIAWMRFDEHGELRAINPEAGFFGVAPGTNYKTNPNAMKTFQKNSIFTNVA------- 523
GDDIAWMRFD G LRAINPE GFFGVAPGT+ TNPNAM T Q N+IFTNVA
Sbjct: 327 GDDIAWMRFDSEGRLRAINPENGFFGVAPGTSATTNPNAMATIQSNTIFTNVAETSDGGV 386
Query: 524 -----------GLVMVAITGKDWK 562
G+ + + GK WK
Sbjct: 387 YWEGIDQPLPPGVTVTSWLGKPWK 410
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,869,559
Number of Sequences: 369166
Number of extensions: 1534867
Number of successful extensions: 3863
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3645
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3782
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4308286840
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)