Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_J21
(651 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q64422|GNPI_MESAU Glucosamine-6-phosphate isomerase (Glu... 321 9e-88
sp|P46926|GNPI_HUMAN Glucosamine-6-phosphate isomerase (Glu... 320 3e-87
sp|Q5R8T8|GNPI_PONPY Glucosamine-6-phosphate isomerase (Glu... 318 1e-86
sp|O88958|GNPI_MOUSE Glucosamine-6-phosphate isomerase (Glu... 317 2e-86
sp|Q9XVJ2|GNPI_CAEEL Probable glucosamine-6-phosphate isome... 278 9e-75
sp|O30564|NAGB_BORBU Glucosamine-6-phosphate deaminase (Glu... 272 6e-73
sp|Q8REG1|NAGB_FUSNN Glucosamine-6-phosphate deaminase (Glu... 263 3e-70
sp|Q9CMF4|NAGB_PASMU Glucosamine-6-phosphate deaminase (Glu... 255 6e-68
sp|Q8A094|NAGB_BACTN Glucosamine-6-phosphate deaminase (Glu... 255 8e-68
sp|Q87K60|NAGB_VIBPA Glucosamine-6-phosphate deaminase (Glu... 254 1e-67
>sp|Q64422|GNPI_MESAU Glucosamine-6-phosphate isomerase (Glucosamine-6-phosphate
deaminase) (GNPDA) (GlcN6P deaminase) (Oscillin)
Length = 289
Score = 321 bits (823), Expect = 9e-88
Identities = 156/216 (72%), Positives = 178/216 (82%)
Frame = +3
Query: 3 QILDFNPNENKLFXXXXXXXXXXXXMYSKLIEYYKAGQISFKYVVTFNMDEYVDLPRNHP 182
+I+ FNP +K F Y KLIEYYK G +SFKYV TFNMDEYV LPR HP
Sbjct: 23 RIIQFNPGPDKYFTMGLPTGSTPLGCYQKLIEYYKNGDLSFKYVKTFNMDEYVGLpreHP 82
Query: 183 QSYHSFMFNNFFKHIDINPNNCYILNGNATNLQVECEQFEKLISQHGGIELFVGGIGPDG 362
+SYHSFM+NNFFKHIDI+P N +IL+GNA +LQ EC+ FE+ I GGIELFVGGIGPDG
Sbjct: 83 ESYHSFMWNNFFKHIDIHPENTHILDGNAADLQAECDAFEEKIRAAGGIELFVGGIGPDG 142
Query: 363 HVAFNEPGSSLVSRTRVKTLAQETIQANSRFFENDLSKVPTNALTVGVGTVMEAREVLIL 542
HVAFNEPGSSLVSRTRVKTLA +TI AN+RFF+ DL+KVPT ALTVGVGTVM+AREV+IL
Sbjct: 143 HVAFNEPGSSLVSRTRVKTLAMDTILANARFFDGDLAKVPTMALTVGVGTVMDAREVMIL 202
Query: 543 ITGSTKALALHKAIEEGVNHMWTVSAFQQHPKTIFV 650
ITG+ KA AL+KAIEEGVNHMWTVSAFQQHP+T+FV
Sbjct: 203 ITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFV 238
>sp|P46926|GNPI_HUMAN Glucosamine-6-phosphate isomerase (Glucosamine-6-phosphate
deaminase) (GNPDA) (GlcN6P deaminase) (Oscillin)
Length = 289
Score = 320 bits (819), Expect = 3e-87
Identities = 154/216 (71%), Positives = 178/216 (82%)
Frame = +3
Query: 3 QILDFNPNENKLFXXXXXXXXXXXXMYSKLIEYYKAGQISFKYVVTFNMDEYVDLPRNHP 182
+I+ FNP K F Y KLIEYYK G +SFKYV TFNMDEYV LPR+HP
Sbjct: 23 RIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGDLSFKYVKTFNMDEYVGLPRDHP 82
Query: 183 QSYHSFMFNNFFKHIDINPNNCYILNGNATNLQVECEQFEKLISQHGGIELFVGGIGPDG 362
+SYHSFM+NNFFKHIDI+P N +IL+GNA +LQ EC+ FE+ I GGIELFVGGIGPDG
Sbjct: 83 ESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDAFEEKIKAAGGIELFVGGIGPDG 142
Query: 363 HVAFNEPGSSLVSRTRVKTLAQETIQANSRFFENDLSKVPTNALTVGVGTVMEAREVLIL 542
H+AFNEPGSSLVSRTRVKTLA +TI AN+RFF+ +L+KVPT ALTVGVGTVM+AREV+IL
Sbjct: 143 HIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTKVPTMALTVGVGTVMDAREVMIL 202
Query: 543 ITGSTKALALHKAIEEGVNHMWTVSAFQQHPKTIFV 650
ITG+ KA AL+KAIEEGVNHMWTVSAFQQHP+T+FV
Sbjct: 203 ITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFV 238
>sp|Q5R8T8|GNPI_PONPY Glucosamine-6-phosphate isomerase (Glucosamine-6-phosphate
deaminase) (GNPDA) (GlcN6P deaminase) (Oscillin)
Length = 289
Score = 318 bits (814), Expect = 1e-86
Identities = 153/216 (70%), Positives = 177/216 (81%)
Frame = +3
Query: 3 QILDFNPNENKLFXXXXXXXXXXXXMYSKLIEYYKAGQISFKYVVTFNMDEYVDLPRNHP 182
+I+ FNP K F Y KLIEYYK G + FKYV TFNMDEYV LPR+HP
Sbjct: 23 RIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGDLPFKYVKTFNMDEYVGLPRDHP 82
Query: 183 QSYHSFMFNNFFKHIDINPNNCYILNGNATNLQVECEQFEKLISQHGGIELFVGGIGPDG 362
+SYHSFM+NNFFKHIDI+P N +IL+GNA +LQ EC+ FE+ I GGIELFVGGIGPDG
Sbjct: 83 ESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDAFEEKIKAAGGIELFVGGIGPDG 142
Query: 363 HVAFNEPGSSLVSRTRVKTLAQETIQANSRFFENDLSKVPTNALTVGVGTVMEAREVLIL 542
H+AFNEPGSSLVSRTRVKTLA +TI AN+RFF+ +L+KVPT ALTVGVGTVM+AREV+IL
Sbjct: 143 HIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTKVPTMALTVGVGTVMDAREVMIL 202
Query: 543 ITGSTKALALHKAIEEGVNHMWTVSAFQQHPKTIFV 650
ITG+ KA AL+KAIEEGVNHMWTVSAFQQHP+T+FV
Sbjct: 203 ITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFV 238
>sp|O88958|GNPI_MOUSE Glucosamine-6-phosphate isomerase (Glucosamine-6-phosphate
deaminase) (GNPDA) (GlcN6P deaminase) (Oscillin)
Length = 289
Score = 317 bits (812), Expect = 2e-86
Identities = 152/216 (70%), Positives = 179/216 (82%)
Frame = +3
Query: 3 QILDFNPNENKLFXXXXXXXXXXXXMYSKLIEYYKAGQISFKYVVTFNMDEYVDLPRNHP 182
+I+ FNP +K F Y KLIEYYK G +SF+YV TFNMDEYV LPR+HP
Sbjct: 23 RIIQFNPGPDKYFTLGLPTGSTPLGCYQKLIEYYKNGDLSFQYVKTFNMDEYVGLPRDHP 82
Query: 183 QSYHSFMFNNFFKHIDINPNNCYILNGNATNLQVECEQFEKLISQHGGIELFVGGIGPDG 362
+SYHSFM++NFFKHIDI+P N +IL+GNA +LQ EC+ FE+ I GGIELFVGGIGPDG
Sbjct: 83 ESYHSFMWDNFFKHIDIHPENTHILDGNAADLQAECDAFEEKIQAAGGIELFVGGIGPDG 142
Query: 363 HVAFNEPGSSLVSRTRVKTLAQETIQANSRFFENDLSKVPTNALTVGVGTVMEAREVLIL 542
H+AFNEPGSSLVSRTRVKTLA +TI AN+RFF+ DL+KVPT ALTVGVGTVM+A+EV+IL
Sbjct: 143 HIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGDLAKVPTMALTVGVGTVMDAKEVMIL 202
Query: 543 ITGSTKALALHKAIEEGVNHMWTVSAFQQHPKTIFV 650
ITG+ KA AL+KAIEEGVNHMWTVSAFQQHP+T+FV
Sbjct: 203 ITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFV 238
>sp|Q9XVJ2|GNPI_CAEEL Probable glucosamine-6-phosphate isomerase (Glucosamine-6-phosphate
deaminase) (GNPDA) (GlcN6P deaminase)
Length = 267
Score = 278 bits (711), Expect = 9e-75
Identities = 133/191 (69%), Positives = 162/191 (84%)
Frame = +3
Query: 78 MYSKLIEYYKAGQISFKYVVTFNMDEYVDLPRNHPQSYHSFMFNNFFKHIDINPNNCYIL 257
MY KLIE+Y AG ISF+ V TFNMDEYVDLPR+H +SYHSFMF+NFF+HIDINP N +IL
Sbjct: 47 MYKKLIEFYNAGVISFEKVKTFNMDEYVDLPRDHTESYHSFMFDNFFRHIDINPANIHIL 106
Query: 258 NGNATNLQVECEQFEKLISQHGGIELFVGGIGPDGHVAFNEPGSSLVSRTRVKTLAQETI 437
+GN ++ + ECE++E+ I + GGI+LFVGGIGPDGH+AFNEPGSSL SRTR+KTL ++TI
Sbjct: 107 DGNTSDHEKECEEYERKIKESGGIDLFVGGIGPDGHIAFNEPGSSLASRTRIKTLNEDTI 166
Query: 438 QANSRFFENDLSKVPTNALTVGVGTVMEAREVLILITGSTKALALHKAIEEGVNHMWTVS 617
QAN+RFF D++KVPT ALTVGV TVM+AREV+ILITGS KALALH+AIE G++HM TVS
Sbjct: 167 QANARFFGGDITKVPTQALTVGVQTVMDAREVMILITGSHKALALHQAIECGISHMCTVS 226
Query: 618 AFQQHPKTIFV 650
A Q H F+
Sbjct: 227 AMQMHRCATFI 237
>sp|O30564|NAGB_BORBU Glucosamine-6-phosphate deaminase (Glucosamine-6-phosphate
isomerase) (GNPDA) (GlcN6P deaminase)
Length = 268
Score = 272 bits (695), Expect = 6e-73
Identities = 131/216 (60%), Positives = 160/216 (74%)
Frame = +3
Query: 3 QILDFNPNENKLFXXXXXXXXXXXXMYSKLIEYYKAGQISFKYVVTFNMDEYVDLPRNHP 182
+I +F+P + F MY LIE K +ISF+ V+TFNMDEY+ + NHP
Sbjct: 23 KINEFSPTKENPFILGLPTGSSPIGMYKNLIELNKNKKISFQNVITFNMDEYIGIEENHP 82
Query: 183 QSYHSFMFNNFFKHIDINPNNCYILNGNATNLQVECEQFEKLISQHGGIELFVGGIGPDG 362
+SYHSFM+NNFF HIDI N ILNGNA+NL+ ECE++EK I GGI LFVGGIGPDG
Sbjct: 83 ESYHSFMWNNFFSHIDIKKENINILNGNASNLKKECEEYEKKIKSFGGIMLFVGGIGPDG 142
Query: 363 HVAFNEPGSSLVSRTRVKTLAQETIQANSRFFENDLSKVPTNALTVGVGTVMEAREVLIL 542
H+AFNEPGSSL SRTR+KTL Q+TI ANSRFFE D++KVP NALTVG+GT+M+++EVLI+
Sbjct: 143 HIAFNEPGSSLTSRTRIKTLTQDTIIANSRFFEGDVNKVPKNALTVGIGTIMDSQEVLII 202
Query: 543 ITGSTKALALHKAIEEGVNHMWTVSAFQQHPKTIFV 650
+ G KA AL AIE+GVNHMWT+SA Q H I V
Sbjct: 203 VNGHNKARALKHAIEKGVNHMWTISALQLHKNAIIV 238
>sp|Q8REG1|NAGB_FUSNN Glucosamine-6-phosphate deaminase (Glucosamine-6-phosphate
isomerase) (GNPDA) (GlcN6P deaminase)
Length = 274
Score = 263 bits (672), Expect = 3e-70
Identities = 125/216 (57%), Positives = 158/216 (73%)
Frame = +3
Query: 3 QILDFNPNENKLFXXXXXXXXXXXXMYSKLIEYYKAGQISFKYVVTFNMDEYVDLPRNHP 182
+I +FNP+ K F MY +LI++ K G ISFK V+TFNMDEYV LP+ HP
Sbjct: 22 KIKEFNPSPEKKFVLGLPTGSTPLQMYKRLIQFNKEGIISFKNVITFNMDEYVGLPKTHP 81
Query: 183 QSYHSFMFNNFFKHIDINPNNCYILNGNATNLQVECEQFEKLISQHGGIELFVGGIGPDG 362
QSYH +M+NNFF HIDI+ N ILNG A N + EC ++E+ I + GGI+LF+GG+G DG
Sbjct: 82 QSYHYYMYNNFFNHIDIDKENVNILNGMAKNYKEECRKYEEKILEVGGIDLFLGGVGVDG 141
Query: 363 HVAFNEPGSSLVSRTRVKTLAQETIQANSRFFENDLSKVPTNALTVGVGTVMEAREVLIL 542
H+AFNEPGSS SRTR K L ++TI NSRFF ND++KVP +ALTVGV T+M+A+EVLI+
Sbjct: 142 HIAFNEPGSSFKSRTREKQLTEDTIIVNSRFFNNDITKVPQSALTVGVSTIMDAKEVLIM 201
Query: 543 ITGSTKALALHKAIEEGVNHMWTVSAFQQHPKTIFV 650
+ G+ KA ALH IEEG+NHMWT+SA Q H K I V
Sbjct: 202 VEGNNKARALHMGIEEGINHMWTISALQLHEKAIIV 237
>sp|Q9CMF4|NAGB_PASMU Glucosamine-6-phosphate deaminase (Glucosamine-6-phosphate
isomerase) (GNPDA) (GlcN6P deaminase)
Length = 267
Score = 255 bits (652), Expect = 6e-68
Identities = 119/216 (55%), Positives = 155/216 (71%)
Frame = +3
Query: 3 QILDFNPNENKLFXXXXXXXXXXXXMYSKLIEYYKAGQISFKYVVTFNMDEYVDLPRNHP 182
+I F P E + F Y LIE YKAG++SFK+VVTFNMDEYV LP+ HP
Sbjct: 23 RINQFQPTEARPFVLGLPTGGTPLKTYEALIELYKAGEVSFKHVVTFNMDEYVGLPKEHP 82
Query: 183 QSYHSFMFNNFFKHIDINPNNCYILNGNATNLQVECEQFEKLISQHGGIELFVGGIGPDG 362
+SYHSFM+ NFF H+DI N ILNGN + EC+++E+ I +G I LF+GG+G DG
Sbjct: 83 ESYHSFMYKNFFDHVDIQEKNINILNGNTEDHDAECQRYEEKIKSYGKIHLFMGGVGVDG 142
Query: 363 HVAFNEPGSSLVSRTRVKTLAQETIQANSRFFENDLSKVPTNALTVGVGTVMEAREVLIL 542
H+AFNEP SSL SRTR+KTL ++T+ ANSRFF+ND++KVP ALT+GVGT+++A EV+IL
Sbjct: 143 HIAFNEPASSLSSRTRIKTLTEDTLIANSRFFDNDVNKVPKYALTIGVGTLLDAEEVMIL 202
Query: 543 ITGSTKALALHKAIEEGVNHMWTVSAFQQHPKTIFV 650
+TG KA AL A+E +NH+WTV+A Q H + I V
Sbjct: 203 VTGYNKAQALQAAVEGSINHLWTVTALQMHRRAIIV 238
>sp|Q8A094|NAGB_BACTN Glucosamine-6-phosphate deaminase (Glucosamine-6-phosphate
isomerase) (GNPDA) (GlcN6P deaminase)
Length = 270
Score = 255 bits (651), Expect = 8e-68
Identities = 123/211 (58%), Positives = 151/211 (71%)
Frame = +3
Query: 18 NPNENKLFXXXXXXXXXXXXMYSKLIEYYKAGQISFKYVVTFNMDEYVDLPRNHPQSYHS 197
NP K F MY LI+ K G +SF+ VVTFNMDEYV LP+ HP+SY+S
Sbjct: 28 NPTPEKPFVLGCPTGSSPLGMYKALIDLNKKGIVSFQNVVTFNMDEYVGLPKEHPESYYS 87
Query: 198 FMFNNFFKHIDINPNNCYILNGNATNLQVECEQFEKLISQHGGIELFVGGIGPDGHVAFN 377
FM+NNFF HIDI N ILNGNA +L EC ++E+ I +GGI+LF+GGIGPDGH+AFN
Sbjct: 88 FMWNNFFSHIDIKKENTNILNGNAPDLDAECARYEEKIKSYGGIDLFMGGIGPDGHIAFN 147
Query: 378 EPGSSLVSRTRVKTLAQETIQANSRFFENDLSKVPTNALTVGVGTVMEAREVLILITGST 557
EPGSSL SRTR KTL +TI ANSRFF+ND++KVP ALTVGVGTV+ A+EV+I++ G
Sbjct: 148 EPGSSLTSRTRQKTLTTDTIIANSRFFDNDINKVPKTALTVGVGTVLSAKEVMIIVNGHN 207
Query: 558 KALALHKAIEEGVNHMWTVSAFQQHPKTIFV 650
KA AL+ A+E + MWT+SA Q H K I V
Sbjct: 208 KARALYHAVEGSITQMWTISALQMHEKGIIV 238
>sp|Q87K60|NAGB_VIBPA Glucosamine-6-phosphate deaminase (Glucosamine-6-phosphate
isomerase) (GNPDA) (GlcN6P deaminase)
Length = 266
Score = 254 bits (650), Expect = 1e-67
Identities = 119/216 (55%), Positives = 155/216 (71%)
Frame = +3
Query: 3 QILDFNPNENKLFXXXXXXXXXXXXMYSKLIEYYKAGQISFKYVVTFNMDEYVDLPRNHP 182
+I DF P + F Y LIE Y+AG++SFK+VVTFNMDEY+ +P +HP
Sbjct: 23 RINDFKPTAERPFVLGLPTGGTPLATYKALIELYQAGEVSFKHVVTFNMDEYIGIPADHP 82
Query: 183 QSYHSFMFNNFFKHIDINPNNCYILNGNATNLQVECEQFEKLISQHGGIELFVGGIGPDG 362
+SY SFM+NNFF HIDI N +LNGN N + EC+++E I +G I LF+GG+G DG
Sbjct: 83 ESYRSFMYNNFFNHIDIQEENINLLNGNTDNHEAECKRYEDKIKSYGKINLFMGGVGNDG 142
Query: 363 HVAFNEPGSSLVSRTRVKTLAQETIQANSRFFENDLSKVPTNALTVGVGTVMEAREVLIL 542
H+AFNEP SSL SRTR+KTL ++T ANSRFF+ D+++VP ALT+GVGT+++A EV+IL
Sbjct: 143 HIAFNEPASSLSSRTRIKTLTEDTRIANSRFFDGDINQVPKYALTIGVGTLLDAEEVMIL 202
Query: 543 ITGSTKALALHKAIEEGVNHMWTVSAFQQHPKTIFV 650
+TG KALAL A+E VNH+WTVSA Q HPK + V
Sbjct: 203 VTGHNKALALEAAVEGCVNHLWTVSALQLHPKAVIV 238
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,737,554
Number of Sequences: 369166
Number of extensions: 1334577
Number of successful extensions: 4042
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3875
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3990
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5365037700
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)