Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_J06
(787 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q00341|VIGLN_HUMAN Vigilin (High density lipoprotein-bin... 142 1e-33
sp|Q8VDJ3|VIGLN_MOUSE Vigilin (High density lipoprotein-bin... 140 5e-33
sp|P81021|VIGLN_CHICK Vigilin 139 7e-33
sp|Q9Z1A6|VIGLN_RAT Vigilin (High density lipoprotein-bindi... 137 4e-32
sp|P06105|SC160_YEAST Protein SCP160 (Protein HX) 73 8e-13
sp|Q80VL1|TDRKH_MOUSE Tudor and KH domain-containing protein 42 0.001
sp|Q9Y2W6|TDRKH_HUMAN Tudor and KH domain-containing protein 42 0.002
sp|P57722|PCBP3_MOUSE Poly(rC)-binding protein 3 (Alpha-CP3) 41 0.004
sp|P57721|PCBP3_HUMAN Poly(rC)-binding protein 3 (Alpha-CP3) 41 0.004
sp|Q01570|SECA_PAVLU Preprotein translocase secA subunit 39 0.016
>sp|Q00341|VIGLN_HUMAN Vigilin (High density lipoprotein-binding protein) (HDL-binding
protein)
Length = 1268
Score = 142 bits (357), Expect = 1e-33
Identities = 87/267 (32%), Positives = 142/267 (53%), Gaps = 8/267 (2%)
Frame = +3
Query: 6 GINTFSTKYNVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNF 185
GI ++ V +++P D I+I G ANL AKAGL E + + E++DR R+F
Sbjct: 994 GIRKMMDEFEVNIHVPAPELQSDIIAITGLAANLDRAKAGLLERVKELQAEQEDRALRSF 1053
Query: 186 ENQVPVPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQ---NSKSEEITIRGYEEDVKKA 356
+ V V +H K+IG++GA I R + +V+IQ PD+ N ++ITI GYE++ + A
Sbjct: 1054 KLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAA 1113
Query: 357 EDELLSMVDRWKAQVIEELHIPRDVHPQLIGSRGSALRKLREQYNVEINFPSKNVDDDNA 536
D +L +V + V E++ + VH ++IG+RG A+RK+ +++ V+I FP D N
Sbjct: 1114 RDAILRIVGELEQMVSEDVPLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNC 1173
Query: 537 NRVEVIGDKENVDKCCDILVEKANELLYEWEERNQVREVKNSIKDRENVNSNNLKEKGPG 716
V V G ENV++ D ++ E L + + ++ E K G
Sbjct: 1174 --VTVTGLPENVEEAIDHILNLEEEYLADVVDSEALQVYMKPPAHEE------AKAPSRG 1225
Query: 717 FLLAGAPW-----QRVPDASSNVDFPT 782
F++ APW ++ PD SS+ +FP+
Sbjct: 1226 FVVRDAPWTASSSEKAPDMSSSEEFPS 1252
Score = 86.7 bits (213), Expect = 7e-17
Identities = 54/183 (29%), Positives = 100/183 (54%), Gaps = 1/183 (0%)
Frame = +3
Query: 72 DFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFHRKLIGQRGANI 251
D I+++GP ++ A+ ++ ++ +D I R ++ + FHR LIG+ GANI
Sbjct: 406 DKITLEGPTEDVNVAQEQIEGMV-------KDLINRMDYVEINIDHKFHRHLIGKSGANI 458
Query: 252 EMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWKAQVIEELHIPRDV 431
+ ++ VS++IP + KS I I G + V++A+ ELL + R + + ++L I +
Sbjct: 459 NRIKDQYKVSVRIPPDSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRF 518
Query: 432 HPQLIGSRGSALRKLREQY-NVEINFPSKNVDDDNANRVEVIGDKENVDKCCDILVEKAN 608
H +IG +G +R++R+++ V INFP D V++ G K V+KC + +
Sbjct: 519 HRTIIGQKGERIREIRDKFPEVIINFPDPAQKSD---IVQLRGPKNEVEKCTKYMQKMVA 575
Query: 609 ELL 617
+L+
Sbjct: 576 DLV 578
Score = 86.7 bits (213), Expect = 7e-17
Identities = 55/194 (28%), Positives = 99/194 (51%), Gaps = 2/194 (1%)
Frame = +3
Query: 36 VVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVF 215
V++N P + D + ++GP+ + + +++ D + ++ VP+ F
Sbjct: 540 VIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVA-------DLVENSYSISVPIFKQF 592
Query: 216 HRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWKA 395
H+ +IG+ GANI+ R + N I +P +NS SE I I G + + A +LS + + A
Sbjct: 593 HKNIIGKGGANIKKIREESNTKIDLPAENSNSETIIITGKRANCEAARSRILS-IQKDLA 651
Query: 396 QVIE-ELHIPRDVHPQLIGSRGSALRKLREQY-NVEINFPSKNVDDDNANRVEVIGDKEN 569
+ E E+ IP +H LIG++G +R + E+ V I+FP V+ ++ V + G +
Sbjct: 652 NIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFP---VEGSGSDTVVIRGPSSD 708
Query: 570 VDKCCDILVEKANE 611
V+K L+ A E
Sbjct: 709 VEKAKKQLLHLAEE 722
Score = 84.0 bits (206), Expect = 4e-16
Identities = 59/195 (30%), Positives = 96/195 (49%), Gaps = 6/195 (3%)
Frame = +3
Query: 9 INTFSTKYNVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFE 188
IN +Y V V IPP ++ + I I+G + AK L EL ENE+
Sbjct: 458 INRIKDQYKVSVRIPPDSEKSNLIRIEGDPQGVQQAKRELLELASRMENER--------T 509
Query: 189 NQVPVPIVFHRKLIGQRGANIEMFRSKF-NVSIQIPDQNSKSEEITIRGYEEDVKKAEDE 365
+ + FHR +IGQ+G I R KF V I PD KS+ + +RG + +V+K
Sbjct: 510 KDLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNEVEKCTKY 569
Query: 366 LLSMVDRWKAQVIEELH-----IPRDVHPQLIGSRGSALRKLREQYNVEINFPSKNVDDD 530
+ MV A ++E + I + H +IG G+ ++K+RE+ N +I+ P++N
Sbjct: 570 MQKMV----ADLVENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAEN---S 622
Query: 531 NANRVEVIGDKENVD 575
N+ + + G + N +
Sbjct: 623 NSETIIITGKRANCE 637
Score = 75.5 bits (184), Expect = 2e-13
Identities = 49/196 (25%), Positives = 93/196 (47%), Gaps = 8/196 (4%)
Frame = +3
Query: 51 PPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFHRKLI 230
P + + D I I G + AK L+ L+ V +V VP HR +I
Sbjct: 942 PGSPRRCDIIIISGRKEKCEAAKEALEALVPV-------------TIEVEVPFDLHRYVI 988
Query: 231 GQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWKAQVIE- 407
GQ+G+ I +F V+I +P +S+ I I G ++ +A+ LL V +A+ +
Sbjct: 989 GQKGSGIRKMMDEFEVNIHVPAPELQSDIIAITGLAANLDRAKAGLLERVKELQAEQEDR 1048
Query: 408 -------ELHIPRDVHPQLIGSRGSALRKLREQYNVEINFPSKNVDDDNANRVEVIGDKE 566
+ + HP++IG +G+ + ++R +++V I FP K+ + +++ + G ++
Sbjct: 1049 ALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEK 1108
Query: 567 NVDKCCDILVEKANEL 614
N + D ++ EL
Sbjct: 1109 NTEAARDAILRIVGEL 1124
Score = 71.6 bits (174), Expect = 2e-12
Identities = 57/242 (23%), Positives = 109/242 (45%), Gaps = 32/242 (13%)
Frame = +3
Query: 36 VVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVF 215
V+V+ P + D +++KG + + AK + E+I + + + +P F
Sbjct: 833 VMVSFPRSGTQSDKVTLKGAKDCVEAAKKRIQEII--------EDLEAQVTLECAIPQKF 884
Query: 216 HRKLIGQRGANIEMFRSKFNVSIQIPDQNS------------------------------ 305
HR ++G +G+ I+ F+V I+ PD+
Sbjct: 885 HRSVMGPKGSRIQQITRDFSVQIKFPDREENAVHSTEPVVQENGDEAGEGREAKDCDPGS 944
Query: 306 --KSEEITIRGYEEDVKKAEDELLSMVDRWKAQVIEELHIPRDVHPQLIGSRGSALRKLR 479
+ + I I G +E + A++ L ++V V E+ +P D+H +IG +GS +RK+
Sbjct: 945 PRRCDIIIISGRKEKCEAAKEALEALV-----PVTIEVEVPFDLHRYVIGQKGSGIRKMM 999
Query: 480 EQYNVEINFPSKNVDDDNANRVEVIGDKENVDKCCDILVEKANELLYEWEERNQVREVKN 659
+++ V I+ P+ + D + + G N+D+ L+E+ EL E E+R +R K
Sbjct: 1000 DEFEVNIHVPAPELQSD---IIAITGLAANLDRAKAGLLERVKELQAEQEDR-ALRSFKL 1055
Query: 660 SI 665
S+
Sbjct: 1056 SV 1057
Score = 70.1 bits (170), Expect = 7e-12
Identities = 49/182 (26%), Positives = 87/182 (47%), Gaps = 2/182 (1%)
Frame = +3
Query: 33 NVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIV 212
N +++P N + I I G RAN A++ + + Q +A E +V +P
Sbjct: 612 NTKIDLPAENSNSETIIITGKRANCEAARSRILSI--------QKDLANIAEVEVSIPAK 663
Query: 213 FHRKLIGQRGANIEMFRSKFN-VSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRW 389
H LIG +G I + V I P + S S+ + IRG DV+KA+ +LL + +
Sbjct: 664 LHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEK 723
Query: 390 KAQVIE-ELHIPRDVHPQLIGSRGSALRKLREQYNVEINFPSKNVDDDNANRVEVIGDKE 566
+ + ++ + H LIG G +RK+R+ + FP+ +D + + + +IG ++
Sbjct: 724 QTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPA--AEDKDQDLITIIGKED 781
Query: 567 NV 572
V
Sbjct: 782 AV 783
Score = 62.0 bits (149), Expect = 2e-09
Identities = 45/182 (24%), Positives = 80/182 (43%), Gaps = 10/182 (5%)
Frame = +3
Query: 57 ANKCLDFISIKGPRANLIDAK--------AGLDELIVVWENEKQDRIARNFENQVPVPIV 212
A CL+ + G L AK +G + ++ + R+ V +P
Sbjct: 101 AKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVAIPKE 160
Query: 213 FHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWK 392
HR +IG+ G ++ K IQIP + S +I I G +E ++KA E+L +
Sbjct: 161 HHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQIKITGTKEGIEKARHEVLLISAEQD 220
Query: 393 AQVIEELHIPRDVHPQLIGSRGSALRKLREQYNVEINFPSKNVDDDNANRVEVI--GDKE 566
+ +E L + + HP + G + ++ ++ IN P +V NR E++ G+KE
Sbjct: 221 KRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPSV-----NRTEIVFTGEKE 275
Query: 567 NV 572
+
Sbjct: 276 QL 277
Score = 61.2 bits (147), Expect = 3e-09
Identities = 37/153 (24%), Positives = 80/153 (52%), Gaps = 1/153 (0%)
Frame = +3
Query: 60 NKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFHRKLIGQR 239
+K D I+I G + +A+ L+ LI +N +D + V HR + +R
Sbjct: 768 DKDQDLITIIGKEDAVREAQKELEALIQNLDNVVEDSML--------VDPKHHRHFVIRR 819
Query: 240 GANIEMFRSKFN-VSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWKAQVIEELH 416
G + ++ V + P ++S+++T++G ++ V+ A+ + +++ +AQV E
Sbjct: 820 GQVLREIAEEYGGVMVSFPRSGTQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTLECA 879
Query: 417 IPRDVHPQLIGSRGSALRKLREQYNVEINFPSK 515
IP+ H ++G +GS ++++ ++V+I FP +
Sbjct: 880 IPQKFHRSVMGPKGSRIQQITRDFSVQIKFPDR 912
Score = 60.8 bits (146), Expect = 4e-09
Identities = 50/200 (25%), Positives = 91/200 (45%), Gaps = 2/200 (1%)
Frame = +3
Query: 36 VVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVF 215
V ++ P D + I+GP +++ AK L L EKQ ++F + +
Sbjct: 686 VHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLA----EEKQ---TKSFTVDIRAKPEY 738
Query: 216 HRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEE-ITIRGYEEDVKKAEDELLSMVDRWK 392
H+ LIG+ G I R + P K ++ ITI G E+ V++A+ EL +++
Sbjct: 739 HKFLIGKGGGKIRKVRDSTGARVIFPAAEDKDQDLITIIGKEDAVREAQKELEALIQNLD 798
Query: 393 AQVIEELHIPRDVHPQLIGSRGSALRKLREQY-NVEINFPSKNVDDDNANRVEVIGDKEN 569
V + + + H + RG LR++ E+Y V ++FP D +V + G K+
Sbjct: 799 NVVEDSMLVDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRSGTQSD---KVTLKGAKD- 854
Query: 570 VDKCCDILVEKANELLYEWE 629
C + ++ E++ + E
Sbjct: 855 ---CVEAAKKRIQEIIEDLE 871
Score = 54.3 bits (129), Expect = 4e-07
Identities = 49/225 (21%), Positives = 103/225 (45%), Gaps = 3/225 (1%)
Frame = +3
Query: 42 VNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFHR 221
+NIPP + I G + L A A + + ++E +K+ + V V H+
Sbjct: 256 INIPPPSVNRTEIVFTGEKEQLAQAVARIKK---IYEEKKK----KTTTIAVEVKKSQHK 308
Query: 222 KLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWKAQV 401
+IG +G +++ + VS++IP +S SE + +RG E + +A E+ + + +
Sbjct: 309 YVIGPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKANSF---T 365
Query: 402 IEELHIPRDVHPQLIGSRGSALRKLREQY-NVEINFPSKNVDDDNANRVEVIGDKENVDK 578
+ + P +H +IG +G L K+ +Q V I F + +++ + G E+V+
Sbjct: 366 VSSVAAPSWLHRFIIGKKGQNLAKITQQMPKVHIEF------TEGEDKITLEGPTEDVNV 419
Query: 579 CCDILVEKANELL--YEWEERNQVREVKNSIKDRENVNSNNLKEK 707
+ + +L+ ++ E N + + + N N +K++
Sbjct: 420 AQEQIEGMVKDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQ 464
>sp|Q8VDJ3|VIGLN_MOUSE Vigilin (High density lipoprotein-binding protein) (HDL-binding
protein)
Length = 1268
Score = 140 bits (352), Expect = 5e-33
Identities = 85/267 (31%), Positives = 142/267 (53%), Gaps = 8/267 (2%)
Frame = +3
Query: 6 GINTFSTKYNVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNF 185
GI ++ V +++P D I+I G ANL AKAGL + + + E++DR R+F
Sbjct: 994 GIRKMMDEFEVNIHVPAPELQSDTIAITGLAANLDRAKAGLLDRVKELQAEQEDRALRSF 1053
Query: 186 ENQVPVPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQ---NSKSEEITIRGYEEDVKKA 356
+ V V +H K+IG++GA I R + V+IQ PD+ N ++ITI GYE++ + A
Sbjct: 1054 KLSVTVDPKYHPKIIGRKGAVITQIRLEHEVNIQFPDKDDGNQPQDQITITGYEKNTEAA 1113
Query: 357 EDELLSMVDRWKAQVIEELHIPRDVHPQLIGSRGSALRKLREQYNVEINFPSKNVDDDNA 536
D +L +V + V E++ + VH ++IG+RG A+RK+ +++ V+I FP D N
Sbjct: 1114 RDAILKIVGELEQMVSEDVPLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNC 1173
Query: 537 NRVEVIGDKENVDKCCDILVEKANELLYEWEERNQVREVKNSIKDRENVNSNNLKEKGPG 716
V V G ENV++ D ++ E L + + ++ E+ + G
Sbjct: 1174 --VTVTGLPENVEEAIDHILNLEEEYLADVVDSEALQVYMKPPAHEES------RAPSKG 1225
Query: 717 FLLAGAPW-----QRVPDASSNVDFPT 782
F++ APW ++ PD SS+ +FP+
Sbjct: 1226 FVVRDAPWTSNSSEKAPDMSSSEEFPS 1252
Score = 86.7 bits (213), Expect = 7e-17
Identities = 54/183 (29%), Positives = 100/183 (54%), Gaps = 1/183 (0%)
Frame = +3
Query: 72 DFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFHRKLIGQRGANI 251
D I+++GP ++ A+ ++ ++ +D I R ++ + FHR LIG+ GANI
Sbjct: 406 DKITLEGPTEDVNVAQEQIEGMV-------KDLINRMDYVEINIDHKFHRHLIGKSGANI 458
Query: 252 EMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWKAQVIEELHIPRDV 431
+ ++ VS++IP + KS I I G + V++A+ ELL + R + + ++L I +
Sbjct: 459 NRIKDQYKVSVRIPPDSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRF 518
Query: 432 HPQLIGSRGSALRKLREQY-NVEINFPSKNVDDDNANRVEVIGDKENVDKCCDILVEKAN 608
H +IG +G +R++R+++ V INFP D V++ G K V+KC + +
Sbjct: 519 HRTIIGQKGERIREIRDKFPEVIINFPDPAQKSD---IVQLRGPKNEVEKCTKYMQKMVA 575
Query: 609 ELL 617
+L+
Sbjct: 576 DLV 578
Score = 86.7 bits (213), Expect = 7e-17
Identities = 55/194 (28%), Positives = 99/194 (51%), Gaps = 2/194 (1%)
Frame = +3
Query: 36 VVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVF 215
V++N P + D + ++GP+ + + +++ D + ++ VP+ F
Sbjct: 540 VIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVA-------DLVENSYSISVPIFKQF 592
Query: 216 HRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWKA 395
H+ +IG+ GANI+ R + N I +P +NS SE I I G + + A +LS + + A
Sbjct: 593 HKNIIGKGGANIKKIREESNTKIDLPAENSNSETIIITGKRANCEAARSRILS-IQKDLA 651
Query: 396 QVIE-ELHIPRDVHPQLIGSRGSALRKLREQY-NVEINFPSKNVDDDNANRVEVIGDKEN 569
+ E E+ IP +H LIG++G +R + E+ V I+FP V+ ++ V + G +
Sbjct: 652 NIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFP---VEGSGSDTVVIRGPSSD 708
Query: 570 VDKCCDILVEKANE 611
V+K L+ A E
Sbjct: 709 VEKAKKQLLHLAEE 722
Score = 84.0 bits (206), Expect = 4e-16
Identities = 59/195 (30%), Positives = 96/195 (49%), Gaps = 6/195 (3%)
Frame = +3
Query: 9 INTFSTKYNVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFE 188
IN +Y V V IPP ++ + I I+G + AK L EL ENE+
Sbjct: 458 INRIKDQYKVSVRIPPDSEKSNLIRIEGDPQGVQQAKRELLELASRMENER--------T 509
Query: 189 NQVPVPIVFHRKLIGQRGANIEMFRSKF-NVSIQIPDQNSKSEEITIRGYEEDVKKAEDE 365
+ + FHR +IGQ+G I R KF V I PD KS+ + +RG + +V+K
Sbjct: 510 KDLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNEVEKCTKY 569
Query: 366 LLSMVDRWKAQVIEELH-----IPRDVHPQLIGSRGSALRKLREQYNVEINFPSKNVDDD 530
+ MV A ++E + I + H +IG G+ ++K+RE+ N +I+ P++N
Sbjct: 570 MQKMV----ADLVENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAEN---S 622
Query: 531 NANRVEVIGDKENVD 575
N+ + + G + N +
Sbjct: 623 NSETIIITGKRANCE 637
Score = 76.6 bits (187), Expect = 7e-14
Identities = 49/196 (25%), Positives = 93/196 (47%), Gaps = 8/196 (4%)
Frame = +3
Query: 51 PPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFHRKLI 230
P + + D I I G + AK L+ L+ V +V VP HR +I
Sbjct: 942 PGSPRRCDIIIISGRKEKCEAAKEALEALVPV-------------TIEVEVPFDLHRYII 988
Query: 231 GQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWKAQVIE- 407
GQ+G+ I +F V+I +P +S+ I I G ++ +A+ LL V +A+ +
Sbjct: 989 GQKGSGIRKMMDEFEVNIHVPAPELQSDTIAITGLAANLDRAKAGLLDRVKELQAEQEDR 1048
Query: 408 -------ELHIPRDVHPQLIGSRGSALRKLREQYNVEINFPSKNVDDDNANRVEVIGDKE 566
+ + HP++IG +G+ + ++R ++ V I FP K+ + +++ + G ++
Sbjct: 1049 ALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHEVNIQFPDKDDGNQPQDQITITGYEK 1108
Query: 567 NVDKCCDILVEKANEL 614
N + D +++ EL
Sbjct: 1109 NTEAARDAILKIVGEL 1124
Score = 65.9 bits (159), Expect = 1e-10
Identities = 40/153 (26%), Positives = 80/153 (52%), Gaps = 1/153 (0%)
Frame = +3
Query: 60 NKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFHRKLIGQR 239
+K D I+I G + +A+ L+ LI EN +D + V HR + +R
Sbjct: 768 DKDQDLITIIGKEDAVREAQKELEALIQNLENVVEDYML--------VDPKHHRHFVIRR 819
Query: 240 GANIEMFRSKFN-VSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWKAQVIEELH 416
G + ++ V + P ++S+++T++G ++ V+ A+ + +++ +AQV E
Sbjct: 820 GQVLREIAEEYGGVMVSFPRSGTQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTVECA 879
Query: 417 IPRDVHPQLIGSRGSALRKLREQYNVEINFPSK 515
IP+ H ++G +GS ++++ YNV+I FP +
Sbjct: 880 IPQKFHRSVMGPKGSRIQQITRDYNVQIKFPDR 912
Score = 65.1 bits (157), Expect = 2e-10
Identities = 46/182 (25%), Positives = 81/182 (44%), Gaps = 10/182 (5%)
Frame = +3
Query: 57 ANKCLDFISIKGPRANLIDAK--------AGLDELIVVWENEKQDRIARNFENQVPVPIV 212
A CL+ + G L AK +G + ++ + R+ VP+P
Sbjct: 101 AKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVPIPKE 160
Query: 213 FHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWK 392
HR +IG+ G ++ K IQIP + S +I I G +E ++KA E+L +
Sbjct: 161 HHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQIKITGTKEGIEKARHEVLLISAEQD 220
Query: 393 AQVIEELHIPRDVHPQLIGSRGSALRKLREQYNVEINFPSKNVDDDNANRVEVI--GDKE 566
+ +E L + + HP + G + ++ ++ IN P +V NR E++ G+KE
Sbjct: 221 KRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPSV-----NRTEIVFTGEKE 275
Query: 567 NV 572
+
Sbjct: 276 QL 277
Score = 61.2 bits (147), Expect = 3e-09
Identities = 51/200 (25%), Positives = 92/200 (46%), Gaps = 2/200 (1%)
Frame = +3
Query: 36 VVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVF 215
V ++ P D + I+GP +++ AK L L EKQ ++F + +
Sbjct: 686 VHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLA----EEKQ---TKSFTVDIRAKPEY 738
Query: 216 HRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEE-ITIRGYEEDVKKAEDELLSMVDRWK 392
H+ LIG+ G I R I P K ++ ITI G E+ V++A+ EL +++ +
Sbjct: 739 HKFLIGKGGGKIRKVRDSTGARIIFPAAEDKDQDLITIIGKEDAVREAQKELEALIQNLE 798
Query: 393 AQVIEELHIPRDVHPQLIGSRGSALRKLREQY-NVEINFPSKNVDDDNANRVEVIGDKEN 569
V + + + H + RG LR++ E+Y V ++FP D +V + G K+
Sbjct: 799 NVVEDYMLVDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRSGTQSD---KVTLKGAKD- 854
Query: 570 VDKCCDILVEKANELLYEWE 629
C + ++ E++ + E
Sbjct: 855 ---CVEAAKKRIQEIIEDLE 871
Score = 54.7 bits (130), Expect = 3e-07
Identities = 49/225 (21%), Positives = 103/225 (45%), Gaps = 3/225 (1%)
Frame = +3
Query: 42 VNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFHR 221
+NIPP + I G + L A A + + ++E +K+ + V V H+
Sbjct: 256 INIPPPSVNRTEIVFTGEKEQLAQAVARIKK---IYEEKKK----KTTTIAVEVKKSQHK 308
Query: 222 KLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWKAQV 401
+IG +G +++ + VS++IP +S SE + +RG E + +A E+ + + +
Sbjct: 309 YVIGPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKANSF---T 365
Query: 402 IEELHIPRDVHPQLIGSRGSALRKLREQY-NVEINFPSKNVDDDNANRVEVIGDKENVDK 578
+ + P +H +IG +G L K+ +Q V I F + +++ + G E+V+
Sbjct: 366 VSSVSAPSWLHRFIIGKKGQNLAKITQQMPKVHIEF------TEGEDKITLEGPTEDVNV 419
Query: 579 CCDILVEKANELL--YEWEERNQVREVKNSIKDRENVNSNNLKEK 707
+ + +L+ ++ E N + + + N N +K++
Sbjct: 420 AQEQIEGMVKDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQ 464
>sp|P81021|VIGLN_CHICK Vigilin
Length = 1270
Score = 139 bits (351), Expect = 7e-33
Identities = 87/268 (32%), Positives = 145/268 (54%), Gaps = 9/268 (3%)
Frame = +3
Query: 6 GINTFSTKYNVVVNIP-PANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARN 182
GI ++ V + +P P + D I+I G ANL AKAGL E + + E++DR R+
Sbjct: 995 GIRKMMDEFEVNIQVPAPELQSSDIITITGLAANLDRAKAGLLERVKELQAEQEDRALRS 1054
Query: 183 FENQVPVPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSE---EITIRGYEEDVKK 353
F+ V V +H K+IG++GA I R++ V+IQ PD++ +S+ +ITI GYE++ +
Sbjct: 1055 FKLTVTVDPKYHPKIIGRKGAVITQIRTEHEVNIQFPDKDDESQAQDQITITGYEKNAEA 1114
Query: 354 AEDELLSMVDRWKAQVIEELHIPRDVHPQLIGSRGSALRKLREQYNVEINFPSKNVDDDN 533
A D ++ +V + V E++ + VH ++IG+RG A+RK+ +++ V+I FP D N
Sbjct: 1115 ARDAIMKIVGELEQMVSEDVTLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPDPN 1174
Query: 534 ANRVEVIGDKENVDKCCDILVEKANELLYEWEERNQVREVKNSIKDRENVNSNNLKEKGP 713
V V G ENV++ D ++ E L + + ++ E+ K
Sbjct: 1175 C--VTVTGLPENVEEAIDHILNLEEEYLADVVDNEAMQVYMKPSSHEES------KVPSK 1226
Query: 714 GFLLAGAPW-----QRVPDASSNVDFPT 782
GF++ AP ++ PD SS+ DFP+
Sbjct: 1227 GFVVRDAPCGTVNNEKAPDMSSSEDFPS 1254
Score = 89.4 bits (220), Expect = 1e-17
Identities = 57/183 (31%), Positives = 98/183 (53%), Gaps = 1/183 (0%)
Frame = +3
Query: 72 DFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFHRKLIGQRGANI 251
D I+ +GP ++ A+ ++ ++ +D I R ++ V FHR LIG+ GANI
Sbjct: 405 DKITSEGPTEDVNVAQEQIEVMV-------KDLINRTDYAEINVDHKFHRHLIGKNGANI 457
Query: 252 EMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWKAQVIEELHIPRDV 431
+ + VS++IP N KS I I G + V++A+ ELL + R + + ++L I +
Sbjct: 458 NRIKDLYKVSVRIPPDNEKSNLIRIEGDPQGVQQAKKELLELASRMENERTKDLIIEQKF 517
Query: 432 HPQLIGSRGSALRKLREQY-NVEINFPSKNVDDDNANRVEVIGDKENVDKCCDILVEKAN 608
H +IG +G +R++RE++ V INFP D V++ G K V+KC + +
Sbjct: 518 HRTIIGQKGERIREIREKFPEVIINFPDPAHKSD---IVQLRGPKNEVEKCTKYMQKMVA 574
Query: 609 ELL 617
+L+
Sbjct: 575 DLV 577
Score = 79.7 bits (195), Expect = 8e-15
Identities = 56/175 (32%), Positives = 86/175 (49%), Gaps = 6/175 (3%)
Frame = +3
Query: 9 INTFSTKYNVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFE 188
IN Y V V IPP N+ + I I+G + AK L EL ENE+
Sbjct: 457 INRIKDLYKVSVRIPPDNEKSNLIRIEGDPQGVQQAKKELLELASRMENER--------T 508
Query: 189 NQVPVPIVFHRKLIGQRGANIEMFRSKF-NVSIQIPDQNSKSEEITIRGYEEDVKKAEDE 365
+ + FHR +IGQ+G I R KF V I PD KS+ + +RG + +V+K
Sbjct: 509 KDLIIEQKFHRTIIGQKGERIREIREKFPEVIINFPDPAHKSDIVQLRGPKNEVEKCTKY 568
Query: 366 LLSMVDRWKAQVIE---ELHIP--RDVHPQLIGSRGSALRKLREQYNVEINFPSK 515
+ MV A ++E + +P + H +IG G+ ++K+RE+ N +I+ P +
Sbjct: 569 MQKMV----ADLVENSFSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPGR 619
Score = 78.6 bits (192), Expect = 2e-14
Identities = 52/197 (26%), Positives = 94/197 (47%), Gaps = 9/197 (4%)
Frame = +3
Query: 51 PPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFHRKLI 230
P + + D I I G R AK L L+ V +V VP HR +I
Sbjct: 943 PSSPRKCDIIIISGRREKCEAAKEALQALVPV-------------TIEVEVPFDLHRYII 989
Query: 231 GQRGANIEMFRSKFNVSIQIPDQNSKSEE-ITIRGYEEDVKKAEDELLSMVDRWKAQVIE 407
GQ+G+ I +F V+IQ+P +S + ITI G ++ +A+ LL V +A+ +
Sbjct: 990 GQKGSGIRKMMDEFEVNIQVPAPELQSSDIITITGLAANLDRAKAGLLERVKELQAEQED 1049
Query: 408 E--------LHIPRDVHPQLIGSRGSALRKLREQYNVEINFPSKNVDDDNANRVEVIGDK 563
+ + HP++IG +G+ + ++R ++ V I FP K+ + +++ + G +
Sbjct: 1050 RALRSFKLTVTVDPKYHPKIIGRKGAVITQIRTEHEVNIQFPDKDDESQAQDQITITGYE 1109
Query: 564 ENVDKCCDILVEKANEL 614
+N + D +++ EL
Sbjct: 1110 KNAEAARDAIMKIVGEL 1126
Score = 72.0 bits (175), Expect = 2e-12
Identities = 46/164 (28%), Positives = 89/164 (54%), Gaps = 4/164 (2%)
Frame = +3
Query: 36 VVVNIP-PANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIV 212
V++N P PA+K D + ++GP+ + + +++ D + +F VP+
Sbjct: 539 VIINFPDPAHKS-DIVQLRGPKNEVEKCTKYMQKMVA-------DLVENSFSISVPIFKQ 590
Query: 213 FHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSE-EITIRGYEEDVKKAEDELLSMVDRW 389
FH+ +IG+ GANI+ R + N I +P + ++ ++ +G E+ VK +L+ + +
Sbjct: 591 FHKNIIGKGGANIKKIREESNTKIDLPGREQATQRQLLSQGREQTVKLLRHRILA-IQKE 649
Query: 390 KAQVIE-ELHIPRDVHPQLIGSRGSALRKLREQY-NVEINFPSK 515
A + E E+ IP +H LIG++G +R + E+ V I+FP++
Sbjct: 650 LANITEVEVSIPSKLHNSLIGAKGRFIRSIMEECGGVHIHFPTE 693
Score = 67.0 bits (162), Expect = 6e-11
Identities = 56/233 (24%), Positives = 105/233 (45%), Gaps = 33/233 (14%)
Frame = +3
Query: 36 VVVNIPPANKCL-DFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIV 212
V+V +P + D +++KG + + AK + E+I + E Q I + +P
Sbjct: 833 VMVRLPTVSGTQSDKVTLKGAKDCVEAAKKRIQEIIE--DLEAQVTI------ECTIPQK 884
Query: 213 FHRKLIGQRGANIEMFRSKFNVSIQIPDQNS----------------------------- 305
FHR ++G +G+ I+ + V I+ PD+
Sbjct: 885 FHRSIMGPKGSRIQQITRDYGVQIKFPDREENPAPVAEPALQENGEEGGEGKDGKDADPS 944
Query: 306 ---KSEEITIRGYEEDVKKAEDELLSMVDRWKAQVIEELHIPRDVHPQLIGSRGSALRKL 476
K + I I G E + A++ L ++V V E+ +P D+H +IG +GS +RK+
Sbjct: 945 SPRKCDIIIISGRREKCEAAKEALQALV-----PVTIEVEVPFDLHRYIIGQKGSGIRKM 999
Query: 477 REQYNVEINFPSKNVDDDNANRVEVIGDKENVDKCCDILVEKANELLYEWEER 635
+++ V I P+ + +++ + + G N+D+ L+E+ EL E E+R
Sbjct: 1000 MDEFEVNIQVPAPEL--QSSDIITITGLAANLDRAKAGLLERVKELQAEQEDR 1050
Score = 65.1 bits (157), Expect = 2e-10
Identities = 47/180 (26%), Positives = 76/180 (42%), Gaps = 8/180 (4%)
Frame = +3
Query: 57 ANKCLDFISIKGPRANLIDAK--------AGLDELIVVWENEKQDRIARNFENQVPVPIV 212
A CLD + G L AK +G E ++ E R+ V +P
Sbjct: 100 AKICLDIMQKTGAHLELSLAKDQGLSIMVSGKLEAVMKARKEIVARLQTQASATVAIPKE 159
Query: 213 FHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWK 392
HR +IG+ G ++ K IQIP + S +I I G +E ++KA E+L +
Sbjct: 160 HHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQIKITGTKEGIEKARHEILLISAEQD 219
Query: 393 AQVIEELHIPRDVHPQLIGSRGSALRKLREQYNVEINFPSKNVDDDNANRVEVIGDKENV 572
+ +E L + + HP + G + +L + IN P +V N + G+KE +
Sbjct: 220 KRAVERLDVEKVYHPFIAGPYNKLVSELMQDTGTRINIPPPSV---NKTEIVFTGEKEQL 276
Score = 59.7 bits (143), Expect = 9e-09
Identities = 37/154 (24%), Positives = 81/154 (52%), Gaps = 2/154 (1%)
Frame = +3
Query: 60 NKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFHRKLIGQR 239
+K + I+I G + +A+ L+ LI +N +D + V HR + +R
Sbjct: 768 DKDQELITIMGTEEAVKEAQKELEALIKNLDNVVEDSMV--------VDPKHHRHFVIRR 819
Query: 240 GANIEMFRSKFN-VSIQIPD-QNSKSEEITIRGYEEDVKKAEDELLSMVDRWKAQVIEEL 413
G + ++ V +++P ++S+++T++G ++ V+ A+ + +++ +AQV E
Sbjct: 820 GQVLREIADEYGGVMVRLPTVSGTQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTIEC 879
Query: 414 HIPRDVHPQLIGSRGSALRKLREQYNVEINFPSK 515
IP+ H ++G +GS ++++ Y V+I FP +
Sbjct: 880 TIPQKFHRSIMGPKGSRIQQITRDYGVQIKFPDR 913
Score = 58.9 bits (141), Expect = 2e-08
Identities = 43/163 (26%), Positives = 77/163 (47%), Gaps = 2/163 (1%)
Frame = +3
Query: 147 WENEKQDRIARNFENQVPVPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEE-IT 323
W EKQ +++ + +H+ LIG+ G NI R I P K +E IT
Sbjct: 719 WAEEKQ---TKSYTVDLRAKPEYHKFLIGKGGGNIRKVRDNTGARIIFPTSEDKDQELIT 775
Query: 324 IRGYEEDVKKAEDELLSMVDRWKAQVIEELHIPRDVHPQLIGSRGSALRKLREQY-NVEI 500
I G EE VK+A+ EL +++ V + + + H + RG LR++ ++Y V +
Sbjct: 776 IMGTEEAVKEAQKELEALIKNLDNVVEDSMVVDPKHHRHFVIRRGQVLREIADEYGGVMV 835
Query: 501 NFPSKNVDDDNANRVEVIGDKENVDKCCDILVEKANELLYEWE 629
P+ V +++V + G K+ C + ++ E++ + E
Sbjct: 836 RLPT--VSGTQSDKVTLKGAKD----CVEAAKKRIQEIIEDLE 872
Score = 52.8 bits (125), Expect = 1e-06
Identities = 49/224 (21%), Positives = 101/224 (45%), Gaps = 3/224 (1%)
Frame = +3
Query: 42 VNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFHR 221
+NIPP + I G + L A A + + ++E +K+ + V V H+
Sbjct: 255 INIPPPSVNKTEIVFTGEKEQLAQAVARVKK---IYEEKKK----KTTTIAVEVKKSQHK 307
Query: 222 KLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWKAQV 401
+IG++G +++ K VS++IP +S SE + +RG E + +A E+ + + +
Sbjct: 308 YVIGRKGNSLQEILEKTGVSVEIPPTDSSSETVILRGEPEKLGQALTEVYAKANSF---T 364
Query: 402 IEELHIPRDVHPQLIGSRGSALRKLREQY-NVEINFPSKNVDDDNANRVEVIGDKENVDK 578
+ + P +H +IG G L K+ +Q + I F + +++ G E+V+
Sbjct: 365 VSSVSAPSWLHRFIIGLFGQNLAKITQQMPKIHIEF------TEGEDKITSEGPTEDVNV 418
Query: 579 CCDILVEKANELL--YEWEERNQVREVKNSIKDRENVNSNNLKE 704
+ + +L+ ++ E N + + + N N +K+
Sbjct: 419 AQEQIEVMVKDLINRTDYAEINVDHKFHRHLIGKNGANINRIKD 462
>sp|Q9Z1A6|VIGLN_RAT Vigilin (High density lipoprotein-binding protein) (HDL-binding
protein)
Length = 1268
Score = 137 bits (344), Expect = 4e-32
Identities = 85/267 (31%), Positives = 140/267 (52%), Gaps = 8/267 (2%)
Frame = +3
Query: 6 GINTFSTKYNVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNF 185
GI ++ V +++P I+I G ANL AKAGL + + + E++DR R+F
Sbjct: 994 GIRKMMDEFEVNIHVPAPELQSHTIAITGLAANLDRAKAGLLDRVKELQAEQEDRALRSF 1053
Query: 186 ENQVPVPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQ---NSKSEEITIRGYEEDVKKA 356
+ V V +H K+IG +GA I R + +V+IQ PD+ N ++ITI GYE++ + A
Sbjct: 1054 KLSVTVDPKYHPKIIGGKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAA 1113
Query: 357 EDELLSMVDRWKAQVIEELHIPRDVHPQLIGSRGSALRKLREQYNVEINFPSKNVDDDNA 536
D +L +V + V E++ + VH ++IG+RG A+RK+ +++ V+I FP D N
Sbjct: 1114 RDAILKIVGELEQMVSEDVPLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNC 1173
Query: 537 NRVEVIGDKENVDKCCDILVEKANELLYEWEERNQVREVKNSIKDRENVNSNNLKEKGPG 716
V V G ENV++ D ++ E L + + ++ E+ K G
Sbjct: 1174 --VTVTGLPENVEEAIDHILNLEEEYLADVVDSEALQVYMKPPAHEES------KAPSKG 1225
Query: 717 FLLAGAPW-----QRVPDASSNVDFPT 782
F++ APW ++ PD SS+ + PT
Sbjct: 1226 FVVRDAPWTSNSSEKAPDMSSSEEIPT 1252
Score = 87.0 bits (214), Expect = 5e-17
Identities = 55/186 (29%), Positives = 102/186 (54%), Gaps = 4/186 (2%)
Frame = +3
Query: 72 DFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFHRKLIGQRGANI 251
D I+++GP ++ A+ ++ ++ +D I R ++ + FHR LIG+ GANI
Sbjct: 406 DKITLEGPTEDVNVAQEQIEGMV-------KDLINRMDYVEINIDHKFHRHLIGKSGANI 458
Query: 252 EMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWKAQVIEELHIPRDV 431
+ ++ VS++IP + KS I I G + V++A+ ELL + R + + ++L I +
Sbjct: 459 NRIKDQYKVSVRIPPDSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRF 518
Query: 432 HPQLIGSRGSALRKLREQY-NVEINFPSKNVDDDNANRVEVI---GDKENVDKCCDILVE 599
H +IG +G +R++R+++ V INFP D A + E++ G K V+KC + +
Sbjct: 519 HRTIIGQKGERIREIRDKFPEVIINFP------DPAQKSEIVQLRGPKNEVEKCTKYMQK 572
Query: 600 KANELL 617
+L+
Sbjct: 573 MVADLV 578
Score = 85.5 bits (210), Expect = 2e-16
Identities = 60/195 (30%), Positives = 96/195 (49%), Gaps = 6/195 (3%)
Frame = +3
Query: 9 INTFSTKYNVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFE 188
IN +Y V V IPP ++ + I I+G + AK L EL ENE+
Sbjct: 458 INRIKDQYKVSVRIPPDSEKSNLIRIEGDPQGVQQAKRELLELASRMENER--------T 509
Query: 189 NQVPVPIVFHRKLIGQRGANIEMFRSKF-NVSIQIPDQNSKSEEITIRGYEEDVKKAEDE 365
+ + FHR +IGQ+G I R KF V I PD KSE + +RG + +V+K
Sbjct: 510 KDLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPDPAQKSEIVQLRGPKNEVEKCTKY 569
Query: 366 LLSMVDRWKAQVIEELH-----IPRDVHPQLIGSRGSALRKLREQYNVEINFPSKNVDDD 530
+ MV A ++E + I + H +IG G+ ++K+RE+ N +I+ P++N
Sbjct: 570 MQKMV----ADLVENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAEN---S 622
Query: 531 NANRVEVIGDKENVD 575
N+ + + G + N +
Sbjct: 623 NSETIVITGKRANCE 637
Score = 85.5 bits (210), Expect = 2e-16
Identities = 54/194 (27%), Positives = 99/194 (51%), Gaps = 2/194 (1%)
Frame = +3
Query: 36 VVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVF 215
V++N P + + + ++GP+ + + +++ D + ++ VP+ F
Sbjct: 540 VIINFPDPAQKSEIVQLRGPKNEVEKCTKYMQKMVA-------DLVENSYSISVPIFKQF 592
Query: 216 HRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWKA 395
H+ +IG+ GANI+ R + N I +P +NS SE I I G + + A +LS + + A
Sbjct: 593 HKNIIGKGGANIKKIREESNTKIDLPAENSNSETIVITGKRANCEAARSRILS-IQKDLA 651
Query: 396 QVIE-ELHIPRDVHPQLIGSRGSALRKLREQY-NVEINFPSKNVDDDNANRVEVIGDKEN 569
+ E E+ IP +H LIG++G +R + E+ V I+FP V+ ++ V + G +
Sbjct: 652 NIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFP---VEGSGSDTVVIRGPSSD 708
Query: 570 VDKCCDILVEKANE 611
V+K L+ A E
Sbjct: 709 VEKAKKQLLHLAEE 722
Score = 76.6 bits (187), Expect = 7e-14
Identities = 49/196 (25%), Positives = 93/196 (47%), Gaps = 8/196 (4%)
Frame = +3
Query: 51 PPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFHRKLI 230
P + + D I I G + AK L+ L+ V +V VP HR +I
Sbjct: 942 PGSPRRCDIIVISGRKEKCEAAKEALEALVPV-------------TIEVEVPFDLHRYII 988
Query: 231 GQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWKAQVIE- 407
GQ+G+ I +F V+I +P +S I I G ++ +A+ LL V +A+ +
Sbjct: 989 GQKGSGIRKMMDEFEVNIHVPAPELQSHTIAITGLAANLDRAKAGLLDRVKELQAEQEDR 1048
Query: 408 -------ELHIPRDVHPQLIGSRGSALRKLREQYNVEINFPSKNVDDDNANRVEVIGDKE 566
+ + HP++IG +G+ + ++R +++V I FP K+ + +++ + G ++
Sbjct: 1049 ALRSFKLSVTVDPKYHPKIIGGKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEK 1108
Query: 567 NVDKCCDILVEKANEL 614
N + D +++ EL
Sbjct: 1109 NTEAARDAILKIVGEL 1124
Score = 70.5 bits (171), Expect = 5e-12
Identities = 50/182 (27%), Positives = 87/182 (47%), Gaps = 2/182 (1%)
Frame = +3
Query: 33 NVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIV 212
N +++P N + I I G RAN A++ + + Q +A E +V +P
Sbjct: 612 NTKIDLPAENSNSETIVITGKRANCEAARSRILSI--------QKDLANIAEVEVSIPAK 663
Query: 213 FHRKLIGQRGANIEMFRSKFN-VSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRW 389
H LIG +G I + V I P + S S+ + IRG DV+KA+ +LL + +
Sbjct: 664 LHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEK 723
Query: 390 KAQVIE-ELHIPRDVHPQLIGSRGSALRKLREQYNVEINFPSKNVDDDNANRVEVIGDKE 566
+ + ++ + H LIG G +RK+R+ I FP+ +D + + + +IG ++
Sbjct: 724 QTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARIIFPA--AEDKDQDLITIIGKED 781
Query: 567 NV 572
V
Sbjct: 782 AV 783
Score = 63.9 bits (154), Expect = 5e-10
Identities = 39/153 (25%), Positives = 80/153 (52%), Gaps = 1/153 (0%)
Frame = +3
Query: 60 NKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFHRKLIGQR 239
+K D I+I G + +A+ L+ LI +N +D + V HR + +R
Sbjct: 768 DKDQDLITIIGKEDAVREAQKELEALIQNLDNVVEDYML--------VDPRHHRHFVIRR 819
Query: 240 GANIEMFRSKFN-VSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWKAQVIEELH 416
G + ++ V + P ++S+++T++G ++ V+ A+ + +++ +AQV E
Sbjct: 820 GQVLREIAEEYGGVMVSFPRSGTQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTLECA 879
Query: 417 IPRDVHPQLIGSRGSALRKLREQYNVEINFPSK 515
IP+ H ++G +GS ++++ YNV+I FP +
Sbjct: 880 IPQKFHRSVMGPKGSRIQQITRDYNVQIKFPDR 912
Score = 63.5 bits (153), Expect = 6e-10
Identities = 45/182 (24%), Positives = 81/182 (44%), Gaps = 10/182 (5%)
Frame = +3
Query: 57 ANKCLDFISIKGPRANLIDAK--------AGLDELIVVWENEKQDRIARNFENQVPVPIV 212
A CL+ + G L AK +G + ++ + R+ VP+P
Sbjct: 101 AKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVPIPKE 160
Query: 213 FHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWK 392
HR +IG+ G ++ K IQIP + S +I I G +E ++KA E+L +
Sbjct: 161 HHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQIKITGTKEGIEKARHEVLLISAEQD 220
Query: 393 AQVIEELHIPRDVHPQLIGSRGSALRKLREQYNVEINFPSKNVDDDNANRVEVI--GDKE 566
+ ++ L + + HP + G + ++ ++ IN P +V NR E++ G+KE
Sbjct: 221 KRAVKRLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPSV-----NRTEIVFTGEKE 275
Query: 567 NV 572
+
Sbjct: 276 QL 277
Score = 60.1 bits (144), Expect = 7e-09
Identities = 51/200 (25%), Positives = 91/200 (45%), Gaps = 2/200 (1%)
Frame = +3
Query: 36 VVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVF 215
V ++ P D + I+GP +++ AK L L EKQ ++F + +
Sbjct: 686 VHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLA----EEKQ---TKSFTVDIRAKPEY 738
Query: 216 HRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEE-ITIRGYEEDVKKAEDELLSMVDRWK 392
H+ LIG+ G I R I P K ++ ITI G E+ V++A+ EL +++
Sbjct: 739 HKFLIGKGGGKIRKVRDSTGARIIFPAAEDKDQDLITIIGKEDAVREAQKELEALIQNLD 798
Query: 393 AQVIEELHIPRDVHPQLIGSRGSALRKLREQY-NVEINFPSKNVDDDNANRVEVIGDKEN 569
V + + + H + RG LR++ E+Y V ++FP D +V + G K+
Sbjct: 799 NVVEDYMLVDPRHHRHFVIRRGQVLREIAEEYGGVMVSFPRSGTQSD---KVTLKGAKD- 854
Query: 570 VDKCCDILVEKANELLYEWE 629
C + ++ E++ + E
Sbjct: 855 ---CVEAAKKRIQEIIEDLE 871
Score = 53.9 bits (128), Expect = 5e-07
Identities = 49/225 (21%), Positives = 102/225 (45%), Gaps = 3/225 (1%)
Frame = +3
Query: 42 VNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFHR 221
+NIPP + I G + L A A + + ++E +K+ + V V H+
Sbjct: 256 INIPPPSVNRTEIVFTGEKEQLAQAVARIKK---IYEEKKK----KTTTIAVEVKKSQHK 308
Query: 222 KLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWKAQV 401
+IG +G +++ + VS++IP +S SE + +RG E + +A E+ + + +
Sbjct: 309 YVIGPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKANSF---T 365
Query: 402 IEELHIPRDVHPQLIGSRGSALRKLREQY-NVEINFPSKNVDDDNANRVEVIGDKENVDK 578
+ + P +H +IG +G L K+ Q V I F + +++ + G E+V+
Sbjct: 366 VSSVSAPSWLHRFIIGKKGQNLAKITHQMPKVHIEF------TEGEDKITLEGPTEDVNV 419
Query: 579 CCDILVEKANELL--YEWEERNQVREVKNSIKDRENVNSNNLKEK 707
+ + +L+ ++ E N + + + N N +K++
Sbjct: 420 AQEQIEGMVKDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQ 464
>sp|P06105|SC160_YEAST Protein SCP160 (Protein HX)
Length = 1222
Score = 73.2 bits (178), Expect = 8e-13
Identities = 39/114 (34%), Positives = 63/114 (55%), Gaps = 6/114 (5%)
Frame = +3
Query: 195 VPVPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQNS------KSEEITIRGYEEDVKKA 356
V +P +LIG +G+N++ R KF I IP++ + K+ E+T+ G E ++ A
Sbjct: 639 VNIPANSVARLIGNKGSNLQQIREKFACQIDIPNEENNNASKDKTVEVTLTGLEYNLTHA 698
Query: 357 EDELLSMVDRWKAQVIEELHIPRDVHPQLIGSRGSALRKLREQYNVEINFPSKN 518
+ L + +W + +EL +P H LIG G+ +L+E+YNV INFP N
Sbjct: 699 KKYLAAEAKKWADIITKELIVPVKFHGSLIGPHGTYRNRLQEKYNVFINFPRDN 752
Score = 69.3 bits (168), Expect = 1e-11
Identities = 46/174 (26%), Positives = 89/174 (51%), Gaps = 7/174 (4%)
Frame = +3
Query: 78 ISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQV-PVPIVFHRKLIGQRGANIE 254
+ I G R N+ DA ++ ++ A +F +V + +H+ ++G G +
Sbjct: 835 LEITGSRQNIKDAAKRVESIVAE---------ASDFVTEVLKIDHKYHKSIVGSGGHILR 885
Query: 255 MFRSKF------NVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWKAQVIEELH 416
SK N S+ IP+ +S++++IT++G ++ VKK +E+ +V + V + +
Sbjct: 886 EIISKAGGEEIRNKSVDIPNADSENKDITVQGPQKFVKKVVEEINKIVKDAENSVTKTID 945
Query: 417 IPRDVHPQLIGSRGSALRKLREQYNVEINFPSKNVDDDNANRVEVIGDKENVDK 578
IP + LIG G R+L ++N+ + P+K DD + ++ + G ENV+K
Sbjct: 946 IPAERKGALIGPGGIVRRQLESEFNINLFVPNK---DDPSGKITITGAPENVEK 996
Score = 62.4 bits (150), Expect = 1e-09
Identities = 62/230 (26%), Positives = 99/230 (43%), Gaps = 7/230 (3%)
Frame = +3
Query: 12 NTFSTKYNVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFEN 191
N KYNV +N P N + ++I+GP + A L L+ +E E ++ N
Sbjct: 736 NRLQEKYNVFINFPRDN---EIVTIRGPSRGVNKAHEELKALL-DFEMENGHKMVIN--- 788
Query: 192 QVPVPIVFHRKLIGQRGANIEMFRSKFNVSIQI-------PDQNSKSEEITIRGYEEDVK 350
VP ++IG+ G NI R+++ V + Q + E+ I G +++K
Sbjct: 789 ---VPAEHVPRIIGKNGDNINDIRAEYGVEMDFLQKSTDPKAQETGEVELEITGSRQNIK 845
Query: 351 KAEDELLSMVDRWKAQVIEELHIPRDVHPQLIGSRGSALRKLREQYNVEINFPSKNVDDD 530
A + S+V V E L I H ++GS G LR++ + E +K+VD
Sbjct: 846 DAAKRVESIVAEASDFVTEVLKIDHKYHKSIVGSGGHILREIISKAGGE-EIRNKSVDIP 904
Query: 531 NANRVEVIGDKENVDKCCDILVEKANELLYEWEERNQVREVKNSIKDREN 680
NA D EN DI V+ + + + V E+ +KD EN
Sbjct: 905 NA-------DSENK----DITVQGPQKFV-----KKVVEEINKIVKDAEN 938
Score = 58.9 bits (141), Expect = 2e-08
Identities = 46/162 (28%), Positives = 87/162 (53%), Gaps = 4/162 (2%)
Frame = +3
Query: 33 NVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVP--VP 206
N V+IP A+ I+++GP+ + K ++E+ ++I ++ EN V +
Sbjct: 898 NKSVDIPNADSENKDITVQGPQKFV---KKVVEEI---------NKIVKDAENSVTKTID 945
Query: 207 IVFHRK--LIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMV 380
I RK LIG G S+FN+++ +P+++ S +ITI G E+V+KAE ++L+ +
Sbjct: 946 IPAERKGALIGPGGIVRRQLESEFNINLFVPNKDDPSGKITITGAPENVEKAEKKILNEI 1005
Query: 381 DRWKAQVIEELHIPRDVHPQLIGSRGSALRKLREQYNVEINF 506
R E+ +P ++ + + RG+ ++KLR +V + F
Sbjct: 1006 IR--ENFDREVDVPASIY-EYVSERGAFIQKLRMDLSVNVRF 1044
Score = 43.9 bits (102), Expect = 5e-04
Identities = 24/91 (26%), Positives = 55/91 (60%)
Frame = +3
Query: 282 IQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWKAQVIEELHIPRDVHPQLIGSRGS 461
+QI + ++T+RG E+ K A S+++ ++ ++IP + +LIG++GS
Sbjct: 596 LQIKLHTPEENQLTVRGDEKAAKAANKIFESILNSPSSKSKMTVNIPANSVARLIGNKGS 655
Query: 462 ALRKLREQYNVEINFPSKNVDDDNANRVEVI 554
L+++RE++ +I+ P N +++NA++ + +
Sbjct: 656 NLQQIREKFACQIDIP--NEENNNASKDKTV 684
Score = 31.2 bits (69), Expect = 3.4
Identities = 19/54 (35%), Positives = 32/54 (59%), Gaps = 1/54 (1%)
Frame = +3
Query: 441 LIGSRGSALRKLREQYNVEINFPSKNVDDDNANRVEVI-GDKENVDKCCDILVE 599
++G GS ++K+RE +V IN P K+ D N V I G K V+K +++++
Sbjct: 1168 IVGPGGSNIKKIREAADVIINVPRKS---DKVNDVVYIRGTKAGVEKAGEMVLK 1218
Score = 30.0 bits (66), Expect = 7.5
Identities = 34/153 (22%), Positives = 67/153 (43%), Gaps = 3/153 (1%)
Frame = +3
Query: 78 ISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFHRKLIGQRG---AN 248
+S+ G ++ AKA + L +V E K I E++ +P + + G
Sbjct: 233 VSLFGDFESVNLAKAKI--LAIVKEETKNATIKLVVEDEKYLPYIDVSEFASDEGDEEVK 290
Query: 249 IEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWKAQVIEELHIPRD 428
++ ++ ++ I P + +K+ + +I+ Y +KK L S +D K ++ + D
Sbjct: 291 VQFYKKSGDIVILGpreKAKATKTSIQDY---LKK----LASNLDEEKVKIPSKFQFLID 343
Query: 429 VHPQLIGSRGSALRKLREQYNVEINFPSKNVDD 527
+L+E+YNV + FPS D+
Sbjct: 344 AE------------ELKEKYNVIVTFPSTPDDE 364
>sp|Q80VL1|TDRKH_MOUSE Tudor and KH domain-containing protein
Length = 560
Score = 42.4 bits (98), Expect = 0.001
Identities = 32/146 (21%), Positives = 71/146 (48%), Gaps = 2/146 (1%)
Frame = +3
Query: 180 NFENQVPVPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEI-TIRGYEEDVKKA 356
+ E ++ VP + +IG++GANI+ R + I + ++ E + I G+ V KA
Sbjct: 52 DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKA 111
Query: 357 EDELLSMVDRWKAQVIEELHIPRDVHPQLIGSRGSALRKLREQYNVEINFPSKNVDDDNA 536
+ + ++ V E+L +P+ ++IG G +R + + +I ++
Sbjct: 112 KAAIHQILTE-NTPVFEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLL 170
Query: 537 NR-VEVIGDKENVDKCCDILVEKANE 611
+R +++ G ++ V +++EK +E
Sbjct: 171 SRLIKISGTQKEVAAAKHLILEKVSE 196
>sp|Q9Y2W6|TDRKH_HUMAN Tudor and KH domain-containing protein
Length = 606
Score = 41.6 bits (96), Expect = 0.002
Identities = 32/146 (21%), Positives = 71/146 (48%), Gaps = 2/146 (1%)
Frame = +3
Query: 180 NFENQVPVPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEI-TIRGYEEDVKKA 356
+ E ++ VP + +IG++GANI+ R + I + ++ E + I G+ V KA
Sbjct: 52 DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKA 111
Query: 357 EDELLSMVDRWKAQVIEELHIPRDVHPQLIGSRGSALRKLREQYNVEINFPSKNVDDDNA 536
+ + ++ V E+L +P+ ++IG G +R + + +I ++
Sbjct: 112 KAAIHQILTE-NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLL 170
Query: 537 NR-VEVIGDKENVDKCCDILVEKANE 611
+R +++ G ++ V +++EK +E
Sbjct: 171 SRLIKISGTQKEVAAAKHLILEKVSE 196
>sp|P57722|PCBP3_MOUSE Poly(rC)-binding protein 3 (Alpha-CP3)
Length = 339
Score = 40.8 bits (94), Expect = 0.004
Identities = 32/141 (22%), Positives = 60/141 (42%), Gaps = 16/141 (11%)
Frame = +3
Query: 225 LIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKA---------EDELLSM 377
+IG++G ++ R + I I + N +TI G + + KA ED + SM
Sbjct: 28 IIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSM 87
Query: 378 VDR---WKAQVIEELHIPRDVHPQLIGSRGSALRKLREQYNVEINFPSKNVDDDNANRVE 548
+ K V L +P LIG GS ++++RE ++ + + V
Sbjct: 88 SNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVT 147
Query: 549 VIGDKENVDKC----CDILVE 599
+ G + + +C C +++E
Sbjct: 148 ISGTPDAIIQCVKQICVVMLE 168
>sp|P57721|PCBP3_HUMAN Poly(rC)-binding protein 3 (Alpha-CP3)
Length = 339
Score = 40.8 bits (94), Expect = 0.004
Identities = 32/141 (22%), Positives = 60/141 (42%), Gaps = 16/141 (11%)
Frame = +3
Query: 225 LIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKA---------EDELLSM 377
+IG++G ++ R + I I + N +TI G + + KA ED + SM
Sbjct: 28 IIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSM 87
Query: 378 VDR---WKAQVIEELHIPRDVHPQLIGSRGSALRKLREQYNVEINFPSKNVDDDNANRVE 548
+ K V L +P LIG GS ++++RE ++ + + V
Sbjct: 88 SNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVT 147
Query: 549 VIGDKENVDKC----CDILVE 599
+ G + + +C C +++E
Sbjct: 148 ISGTPDAIIQCVKQICVVMLE 168
>sp|Q01570|SECA_PAVLU Preprotein translocase secA subunit
Length = 891
Score = 38.9 bits (89), Expect = 0.016
Identities = 50/186 (26%), Positives = 82/186 (44%), Gaps = 20/186 (10%)
Frame = +3
Query: 210 VFHRKLIGQRGANI---EMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMV 380
+F++KL G G + + F+ +N+S+ N K I +EDV S+
Sbjct: 357 LFYKKLSGMTGTALTEAKEFKKIYNLSVDCVPINKKVNRID----KEDVVYK-----SLY 407
Query: 381 DRWKAQVIEELHIPRDVHPQLIGS----RGSALRKLREQYNVEINFPSKNVDDDNANRVE 548
+WKA + E L I P LIG+ + L ++YN++ + + ++ AN E
Sbjct: 408 AKWKAVLYESLSIHEQGRPLLIGTSNVKNSEIVSGLLKEYNIKHSLLNAK-PENAANESE 466
Query: 549 VI---GDKENV-------DKCCDILVEKANELLYEWEERNQVREVKNSIKDR---ENVNS 689
+I G K +V + DIL+ + L + E R R + S+ D +N
Sbjct: 467 IIAQAGRKGSVTIATNMAGRGTDILLGGNPDFLTKGELRYIFRSIVLSLDDMTVPKNELI 526
Query: 690 NNLKEK 707
NNLK K
Sbjct: 527 NNLKYK 532
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82,042,781
Number of Sequences: 369166
Number of extensions: 1540494
Number of successful extensions: 5624
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5328
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5561
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7405750800
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)