Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_I22
(656 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P40427|EXD_DROME Homeobox protein extradenticle 137 3e-32
sp|P40425|PBX2_HUMAN Pre-B-cell leukemia transcription fact... 136 4e-32
sp|O35984|PBX2_MOUSE Pre-B-cell leukemia transcription fact... 136 4e-32
sp|P41778|PBX1_MOUSE Pre-B-cell leukemia transcription fact... 135 9e-32
sp|P40426|PBX3_HUMAN Pre-B-cell leukemia transcription fact... 135 1e-31
sp|O35317|PBX3_MOUSE Pre-B-cell leukemia transcription fact... 135 1e-31
sp|P41779|HM20_CAEEL Homeobox protein ceh-20 129 9e-30
sp|Q9BYU1|PBX4_HUMAN Pre-B-cell leukemia transcription fact... 124 2e-28
sp|Q99NE9|PBX4_MOUSE Pre-B-cell leukemia transcription fact... 123 4e-28
sp|Q19503|HM40_CAEEL Homeobox protein ceh-40 98 2e-20
>sp|P40427|EXD_DROME Homeobox protein extradenticle
Length = 376
Score = 137 bits (344), Expect = 3e-32
Identities = 64/70 (91%), Positives = 69/70 (98%)
Frame = +3
Query: 3 KRRNFSKEATEILNEYFYSHLANPYPSEEAKDELAKKCGITVSQVSNWFGNKRIRYKKNI 182
KRRNFSK+A+EILNEYFYSHL+NPYPSEEAK+ELA+KCGITVSQVSNWFGNKRIRYKKNI
Sbjct: 241 KRRNFSKQASEILNEYFYSHLSNPYPSEEAKEELARKCGITVSQVSNWFGNKRIRYKKNI 300
Query: 183 VKAQEEANLY 212
KAQEEANLY
Sbjct: 301 GKAQEEANLY 310
>sp|P40425|PBX2_HUMAN Pre-B-cell leukemia transcription factor 2 (Homeobox protein PBX2)
(G17 protein)
Length = 430
Score = 136 bits (343), Expect = 4e-32
Identities = 70/106 (66%), Positives = 76/106 (71%)
Frame = +3
Query: 3 KRRNFSKEATEILNEYFYSHLANPYPSEEAKDELAKKCGITVSQVSNWFGNKRIRYKKNI 182
KRRNFSK+ATE+LNEYFYSHL+NPYPSEEAK+ELAKKCGITVSQVSNWFGNKRIRYKKNI
Sbjct: 247 KRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNI 306
Query: 183 VKAQEEANLYXXXXXXXXXXXXXXXXXXGQMSASCPTVSTSMSYGG 320
K QEEAN+Y G S PT +S GG
Sbjct: 307 GKFQEEANIY-------AVKTAVSVTQGGHSRTSSPTPPSSAGSGG 345
>sp|O35984|PBX2_MOUSE Pre-B-cell leukemia transcription factor 2 (Homeobox protein PBX2)
Length = 430
Score = 136 bits (343), Expect = 4e-32
Identities = 70/106 (66%), Positives = 76/106 (71%)
Frame = +3
Query: 3 KRRNFSKEATEILNEYFYSHLANPYPSEEAKDELAKKCGITVSQVSNWFGNKRIRYKKNI 182
KRRNFSK+ATE+LNEYFYSHL+NPYPSEEAK+ELAKKCGITVSQVSNWFGNKRIRYKKNI
Sbjct: 247 KRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNI 306
Query: 183 VKAQEEANLYXXXXXXXXXXXXXXXXXXGQMSASCPTVSTSMSYGG 320
K QEEAN+Y G S PT +S GG
Sbjct: 307 GKFQEEANIY-------AVKTAVSVAQGGHSRTSSPTPPSSAGSGG 345
>sp|P41778|PBX1_MOUSE Pre-B-cell leukemia transcription factor 1 (Homeobox protein PBX1)
sp|P40424|PBX1_HUMAN Pre-B-cell leukemia transcription factor 1 (Homeobox protein PBX1)
(Homeobox protein PRL)
Length = 430
Score = 135 bits (340), Expect = 9e-32
Identities = 63/70 (90%), Positives = 68/70 (97%)
Frame = +3
Query: 3 KRRNFSKEATEILNEYFYSHLANPYPSEEAKDELAKKCGITVSQVSNWFGNKRIRYKKNI 182
KRRNF+K+ATEILNEYFYSHL+NPYPSEEAK+ELAKKCGITVSQVSNWFGNKRIRYKKNI
Sbjct: 236 KRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNI 295
Query: 183 VKAQEEANLY 212
K QEEAN+Y
Sbjct: 296 GKFQEEANIY 305
>sp|P40426|PBX3_HUMAN Pre-B-cell leukemia transcription factor 3 (Homeobox protein PBX3)
Length = 434
Score = 135 bits (339), Expect = 1e-31
Identities = 64/70 (91%), Positives = 67/70 (95%)
Frame = +3
Query: 3 KRRNFSKEATEILNEYFYSHLANPYPSEEAKDELAKKCGITVSQVSNWFGNKRIRYKKNI 182
KRRNFSK+ATEILNEYFYSHL+NPYPSEEAK+ELAKKC ITVSQVSNWFGNKRIRYKKNI
Sbjct: 238 KRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKKNI 297
Query: 183 VKAQEEANLY 212
K QEEANLY
Sbjct: 298 GKFQEEANLY 307
>sp|O35317|PBX3_MOUSE Pre-B-cell leukemia transcription factor 3 (Homeobox protein PBX3)
Length = 434
Score = 135 bits (339), Expect = 1e-31
Identities = 64/70 (91%), Positives = 67/70 (95%)
Frame = +3
Query: 3 KRRNFSKEATEILNEYFYSHLANPYPSEEAKDELAKKCGITVSQVSNWFGNKRIRYKKNI 182
KRRNFSK+ATEILNEYFYSHL+NPYPSEEAK+ELAKKC ITVSQVSNWFGNKRIRYKKNI
Sbjct: 238 KRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKKNI 297
Query: 183 VKAQEEANLY 212
K QEEANLY
Sbjct: 298 GKFQEEANLY 307
>sp|P41779|HM20_CAEEL Homeobox protein ceh-20
Length = 338
Score = 129 bits (323), Expect = 9e-30
Identities = 57/70 (81%), Positives = 67/70 (95%)
Frame = +3
Query: 3 KRRNFSKEATEILNEYFYSHLANPYPSEEAKDELAKKCGITVSQVSNWFGNKRIRYKKNI 182
KRRNFSK+ATE+LNEYFY HL+NPYPSEEAK++LA++C ITVSQVSNWFGNKRIRYKKN+
Sbjct: 191 KRRNFSKQATEVLNEYFYGHLSNPYPSEEAKEDLARQCNITVSQVSNWFGNKRIRYKKNM 250
Query: 183 VKAQEEANLY 212
KAQEEA++Y
Sbjct: 251 AKAQEEASMY 260
>sp|Q9BYU1|PBX4_HUMAN Pre-B-cell leukemia transcription factor 4 (Homeobox protein PBX4)
Length = 330
Score = 124 bits (312), Expect = 2e-28
Identities = 57/70 (81%), Positives = 65/70 (92%)
Frame = +3
Query: 3 KRRNFSKEATEILNEYFYSHLANPYPSEEAKDELAKKCGITVSQVSNWFGNKRIRYKKNI 182
KRRNFSK+ATE+LNEYFYSHL NPYPSEEAK+ELA+K G+T+SQVSNWFGNKRIRYKKN+
Sbjct: 169 KRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKKNM 228
Query: 183 VKAQEEANLY 212
K QEEA +Y
Sbjct: 229 GKFQEEATIY 238
>sp|Q99NE9|PBX4_MOUSE Pre-B-cell leukemia transcription factor 4 (Homeobox protein PBX4)
Length = 378
Score = 123 bits (309), Expect = 4e-28
Identities = 57/70 (81%), Positives = 64/70 (91%)
Frame = +3
Query: 3 KRRNFSKEATEILNEYFYSHLANPYPSEEAKDELAKKCGITVSQVSNWFGNKRIRYKKNI 182
KRRNFSK+AT++LNEYFYSHL+NPYPSEE K+ELA+K GITVSQVSNWFGNKRIRYKKN
Sbjct: 218 KRRNFSKQATDVLNEYFYSHLSNPYPSEETKEELARKGGITVSQVSNWFGNKRIRYKKNT 277
Query: 183 VKAQEEANLY 212
K QEEA +Y
Sbjct: 278 GKFQEEATMY 287
>sp|Q19503|HM40_CAEEL Homeobox protein ceh-40
Length = 329
Score = 98.2 bits (243), Expect = 2e-20
Identities = 44/66 (66%), Positives = 55/66 (83%)
Frame = +3
Query: 3 KRRNFSKEATEILNEYFYSHLANPYPSEEAKDELAKKCGITVSQVSNWFGNKRIRYKKNI 182
KRRNFSK +TEILNEYF +++ +PYPSEE K LA +C I+V+QVSNWFGNKRIRYKK +
Sbjct: 190 KRRNFSKTSTEILNEYFLANINHPYPSEEVKQALAMQCNISVAQVSNWFGNKRIRYKKTM 249
Query: 183 VKAQEE 200
K ++E
Sbjct: 250 AKNEDE 255
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,763,188
Number of Sequences: 369166
Number of extensions: 1135985
Number of successful extensions: 3888
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3801
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3887
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5462583840
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)