Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_H18
(812 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q01406|SRC8_CHICK Src substrate protein p85 (p80) (Corta... 336 4e-92
sp|Q14247|SRC8_HUMAN Src substrate cortactin (Amplaxin) (On... 333 4e-91
sp|Q60598|SRC8_MOUSE Src substrate cortactin 330 4e-90
sp|P14317|HCLS1_HUMAN Hematopoietic lineage cell-specific p... 197 3e-50
sp|P49710|HCLS1_MOUSE Hematopoietic lineage cell-specific p... 195 1e-49
sp|Q6XPR3|RPTN_HUMAN Repetin 64 5e-10
sp|Q86YZ3|HORN_HUMAN Hornerin 54 5e-07
sp|P20930|FILA_HUMAN Filaggrin precursor 48 4e-05
sp|O76743|GLH4_CAEEL ATP-dependent RNA helicase glh-4 (Germ... 41 0.004
sp|Q8VHD8|HORN_MOUSE Hornerin 38 0.038
>sp|Q01406|SRC8_CHICK Src substrate protein p85 (p80) (Cortactin)
Length = 563
Score = 336 bits (862), Expect = 4e-92
Identities = 154/241 (63%), Positives = 199/241 (82%)
Frame = +3
Query: 72 SQGFGGKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDYSKGFGGKYGVQKDRQDKAAVGWE 251
S G+GGK+GV+ DR DKSA G EYQ+++ KH SQ D KGFGGK+GVQ DR D++AVG+E
Sbjct: 90 SHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVKGFGGKFGVQTDRVDQSAVGFE 149
Query: 252 HKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYG 431
++ + EKH+SQKDYS GFGGK+GVQ +R DKSAVG++++ +TEKH SQ+DYSKGFGGKYG
Sbjct: 150 YQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQGKTEKHESQKDYSKGFGGKYG 209
Query: 432 VQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKHG 611
V D+ DK AVG+E++ + KH SQ+DY +GFGGKFGVQ +RQDK A+GW+H+E+ + H
Sbjct: 210 VDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKVQLHE 269
Query: 612 SQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGKHSSQTDQSKGFGGKFGVQSDRQDKS 791
SQ+DY GFGGK+GVQT+RQD SAVG+++KE++ KH SQ D SKGFGGK+GVQ DR DK+
Sbjct: 270 SQKDYKSGFGGKFGVQTERQDPSAVGFDYKEKLAKHESQQDYSKGFGGKYGVQKDRMDKN 329
Query: 792 A 794
A
Sbjct: 330 A 330
Score = 335 bits (858), Expect = 1e-91
Identities = 154/235 (65%), Positives = 195/235 (82%)
Frame = +3
Query: 3 MDKCAVGNDYVAAVDKHTSQKDYSQGFGGKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDY 182
MDK AVG++Y + + KH SQ D +GFGGK+GVQ+DR D+SA G+EYQ + +KH SQ+DY
Sbjct: 104 MDKSAVGHEYQSKLSKHCSQVDSVKGFGGKFGVQTDRVDQSAVGFEYQGKTEKHASQKDY 163
Query: 183 SKGFGGKYGVQKDRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWE 362
S GFGGKYGVQ DR DK+AVG++++ + EKH SQKDYS+GFGGK+GV K++ DKSAVG+E
Sbjct: 164 SSGFGGKYGVQADRVDKSAVGFDYQGKTEKHESQKDYSKGFGGKYGVDKDKVDKSAVGFE 223
Query: 363 HKEETEKHGSQQDYSKGFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFG 542
++ +TEKH SQ+DY KGFGGK+GVQTDRQDKCA+GW+H+E++ H SQ+DY GFGGKFG
Sbjct: 224 YQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKVQLHESQKDYKSGFGGKFG 283
Query: 543 VQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEE 707
VQ ERQD SAVG+++KE+ KH SQQDYSKGFGGKYGVQ DR DK+A +E E+
Sbjct: 284 VQTERQDPSAVGFDYKEKLAKHESQQDYSKGFGGKYGVQKDRMDKNAATFEDIEK 338
Score = 289 bits (740), Expect = 6e-78
Identities = 133/208 (63%), Positives = 174/208 (83%)
Frame = +3
Query: 183 SKGFGGKYGVQKDRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWE 362
S G+GGK+GV++DR DK+AVG E++++L KH SQ D +GFGGKFGVQ +R D+SAVG+E
Sbjct: 90 SHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVKGFGGKFGVQTDRVDQSAVGFE 149
Query: 363 HKEETEKHGSQQDYSKGFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFG 542
++ +TEKH SQ+DYS GFGGKYGVQ DR DK AVG++++ + KH SQ+DYS+GFGGK+G
Sbjct: 150 YQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQGKTEKHESQKDYSKGFGGKYG 209
Query: 543 VQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGKHS 722
V K++ DKSAVG+E++ +TEKH SQ+DY KGFGGK+GVQTDRQDK A+GW+H+E+V H
Sbjct: 210 VDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKVQLHE 269
Query: 723 SQTDQSKGFGGKFGVQSDRQDKSALGWD 806
SQ D GFGGKFGVQ++RQD SA+G+D
Sbjct: 270 SQKDYKSGFGGKFGVQTERQDPSAVGFD 297
>sp|Q14247|SRC8_HUMAN Src substrate cortactin (Amplaxin) (Oncogene EMS1)
Length = 550
Score = 333 bits (853), Expect = 4e-91
Identities = 153/243 (62%), Positives = 196/243 (80%)
Frame = +3
Query: 3 MDKCAVGNDYVAAVDKHTSQKDYSQGFGGKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDY 182
MDK AVG++Y + + KH SQ D +GFGGK+GVQ DR D+SA G+EYQ + +KH SQ+DY
Sbjct: 95 MDKSAVGHEYQSKLSKHCSQVDSVRGFGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDY 154
Query: 183 SKGFGGKYGVQKDRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWE 362
S GFGGKYGVQ DR DK+AVG++++ + EKH SQ+DYS+GFGGK+G+ K++ DKSAVG+E
Sbjct: 155 SSGFGGKYGVQADRVDKSAVGFDYQGKTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFE 214
Query: 363 HKEETEKHGSQQDYSKGFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFG 542
++ +TEKH SQ+DY KGFGGK+GVQTDRQDKCA+GW+H+E+L H SQ+DY GFGGKFG
Sbjct: 215 YQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFG 274
Query: 543 VQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGKHS 722
VQ ERQD +AVG+++KE+ KH SQQDYSKGFGGKYGVQ DR DK+A +E +V
Sbjct: 275 VQSERQDSAAVGFDYKEKLAKHESQQDYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAY 334
Query: 723 SQT 731
+T
Sbjct: 335 QKT 337
Score = 332 bits (850), Expect = 1e-90
Identities = 150/241 (62%), Positives = 199/241 (82%)
Frame = +3
Query: 72 SQGFGGKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDYSKGFGGKYGVQKDRQDKAAVGWE 251
S G+GGK+GV+ DR DKSA G EYQ+++ KH SQ D +GFGGK+GVQ DR D++AVG+E
Sbjct: 81 SHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRGFGGKFGVQMDRVDQSAVGFE 140
Query: 252 HKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYG 431
++ + EKH+SQKDYS GFGGK+GVQ +R DKSAVG++++ +TEKH SQ+DYSKGFGGKYG
Sbjct: 141 YQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQGKTEKHESQRDYSKGFGGKYG 200
Query: 432 VQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKHG 611
+ D+ DK AVG+E++ + KH SQ+DY +GFGGKFGVQ +RQDK A+GW+H+E+ + H
Sbjct: 201 IDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKLQLHE 260
Query: 612 SQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGKHSSQTDQSKGFGGKFGVQSDRQDKS 791
SQ+DY GFGGK+GVQ++RQD +AVG+++KE++ KH SQ D SKGFGGK+GVQ DR DK+
Sbjct: 261 SQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQDYSKGFGGKYGVQKDRMDKN 320
Query: 792 A 794
A
Sbjct: 321 A 321
Score = 288 bits (736), Expect = 2e-77
Identities = 131/208 (62%), Positives = 174/208 (83%)
Frame = +3
Query: 183 SKGFGGKYGVQKDRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWE 362
S G+GGK+GV++DR DK+AVG E++++L KH SQ D +GFGGKFGVQ +R D+SAVG+E
Sbjct: 81 SHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRGFGGKFGVQMDRVDQSAVGFE 140
Query: 363 HKEETEKHGSQQDYSKGFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFG 542
++ +TEKH SQ+DYS GFGGKYGVQ DR DK AVG++++ + KH SQ+DYS+GFGGK+G
Sbjct: 141 YQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQGKTEKHESQRDYSKGFGGKYG 200
Query: 543 VQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGKHS 722
+ K++ DKSAVG+E++ +TEKH SQ+DY KGFGGK+GVQTDRQDK A+GW+H+E++ H
Sbjct: 201 IDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKLQLHE 260
Query: 723 SQTDQSKGFGGKFGVQSDRQDKSALGWD 806
SQ D GFGGKFGVQS+RQD +A+G+D
Sbjct: 261 SQKDYKTGFGGKFGVQSERQDSAAVGFD 288
>sp|Q60598|SRC8_MOUSE Src substrate cortactin
Length = 546
Score = 330 bits (845), Expect = 4e-90
Identities = 151/236 (63%), Positives = 192/236 (81%)
Frame = +3
Query: 3 MDKCAVGNDYVAAVDKHTSQKDYSQGFGGKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDY 182
MD+ AVG++Y + + KH SQ D +GFGGK+GVQ DR D+SA G+EYQ + +KH SQ+DY
Sbjct: 95 MDRSAVGHEYQSKLSKHCSQVDSVRGFGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDY 154
Query: 183 SKGFGGKYGVQKDRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWE 362
S GFGGKYGVQ DR DK+AVG++++ + EKH SQKDYS+GFGGK+G+ K++ DKSAVG+E
Sbjct: 155 SSGFGGKYGVQADRVDKSAVGFDYQGKTEKHESQKDYSKGFGGKYGIDKDKVDKSAVGFE 214
Query: 363 HKEETEKHGSQQDYSKGFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFG 542
++ +TEKH SQ+DY KGFGGK+GVQTDRQDKCA+GW+H+E+L H SQ+DY GFGGKFG
Sbjct: 215 YQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFG 274
Query: 543 VQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEV 710
VQ ERQD SAVG+++KE KH QQDY+KGFGGKYGVQ DR DK+A +E +V
Sbjct: 275 VQSERQDSSAVGFDYKERLAKHEPQQDYAKGFGGKYGVQKDRMDKNASTFEEVVQV 330
Score = 328 bits (841), Expect = 1e-89
Identities = 148/241 (61%), Positives = 197/241 (81%)
Frame = +3
Query: 72 SQGFGGKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDYSKGFGGKYGVQKDRQDKAAVGWE 251
S G+GGK+GV+ DR D+SA G EYQ+++ KH SQ D +GFGGK+GVQ DR D++AVG+E
Sbjct: 81 SHGYGGKFGVEQDRMDRSAVGHEYQSKLSKHCSQVDSVRGFGGKFGVQMDRVDQSAVGFE 140
Query: 252 HKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYG 431
++ + EKH+SQKDYS GFGGK+GVQ +R DKSAVG++++ +TEKH SQ+DYSKGFGGKYG
Sbjct: 141 YQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQGKTEKHESQKDYSKGFGGKYG 200
Query: 432 VQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKHG 611
+ D+ DK AVG+E++ + KH SQ+DY +GFGGKFGVQ +RQDK A+GW+H+E+ + H
Sbjct: 201 IDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKLQLHE 260
Query: 612 SQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGKHSSQTDQSKGFGGKFGVQSDRQDKS 791
SQ+DY GFGGK+GVQ++RQD SAVG+++KE + KH Q D +KGFGGK+GVQ DR DK+
Sbjct: 261 SQKDYKTGFGGKFGVQSERQDSSAVGFDYKERLAKHEPQQDYAKGFGGKYGVQKDRMDKN 320
Query: 792 A 794
A
Sbjct: 321 A 321
Score = 288 bits (736), Expect = 2e-77
Identities = 131/208 (62%), Positives = 174/208 (83%)
Frame = +3
Query: 183 SKGFGGKYGVQKDRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWE 362
S G+GGK+GV++DR D++AVG E++++L KH SQ D +GFGGKFGVQ +R D+SAVG+E
Sbjct: 81 SHGYGGKFGVEQDRMDRSAVGHEYQSKLSKHCSQVDSVRGFGGKFGVQMDRVDQSAVGFE 140
Query: 363 HKEETEKHGSQQDYSKGFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFG 542
++ +TEKH SQ+DYS GFGGKYGVQ DR DK AVG++++ + KH SQ+DYS+GFGGK+G
Sbjct: 141 YQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQGKTEKHESQKDYSKGFGGKYG 200
Query: 543 VQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGKHS 722
+ K++ DKSAVG+E++ +TEKH SQ+DY KGFGGK+GVQTDRQDK A+GW+H+E++ H
Sbjct: 201 IDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKLQLHE 260
Query: 723 SQTDQSKGFGGKFGVQSDRQDKSALGWD 806
SQ D GFGGKFGVQS+RQD SA+G+D
Sbjct: 261 SQKDYKTGFGGKFGVQSERQDSSAVGFD 288
>sp|P14317|HCLS1_HUMAN Hematopoietic lineage cell-specific protein (Hematopoietic
cell-specific LYN substrate 1) (LckBP1) (p75)
Length = 486
Score = 197 bits (501), Expect = 3e-50
Identities = 87/137 (63%), Positives = 117/137 (85%)
Frame = +3
Query: 72 SQGFGGKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDYSKGFGGKYGVQKDRQDKAAVGWE 251
S G+GG++GV+ DR DKSA G EY AEV+KH SQ D +KGFGGKYGV++DR DK+AVG++
Sbjct: 80 SHGYGGRFGVERDRMDKSAVGHEYVAEVEKHSSQTDAAKGFGGKYGVERDRADKSAVGFD 139
Query: 252 HKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYG 431
+K E+EKH+SQKDYS+GFGG++GV+K++ DK+A+G+++K ETEKH SQ+DY+KGFGG+YG
Sbjct: 140 YKGEVEKHTSQKDYSRGFGGRYGVEKDKWDKAALGYDYKGETEKHESQRDYAKGFGGQYG 199
Query: 432 VQTDRQDKCAVGWEHKE 482
+Q DR DK AVG+ E
Sbjct: 200 IQKDRVDKSAVGFNEME 216
Score = 191 bits (485), Expect = 2e-48
Identities = 99/214 (46%), Positives = 134/214 (62%), Gaps = 19/214 (8%)
Frame = +3
Query: 120 KSAAGWEYQAEVQKHGSQQDYSKGFGGKYGVQKDR------------------QDKAAVG 245
KS G + V+ G D F ++ R Q + V
Sbjct: 3 KSVVGHDVSVSVETQGDDWDTDPDFVNDISEKEQRWGAKTIEGSGRTEHINIHQLRNKVS 62
Query: 246 WEHKAELEKH-SSQKDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGG 422
EH +K S S G+GG+FGV+++R DKSAVG E+ E EKH SQ D +KGFGG
Sbjct: 63 EEHDVLRKKEMESGPKASHGYGGRFGVERDRMDKSAVGHEYVAEVEKHSSQTDAAKGFGG 122
Query: 423 KYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEHKEETE 602
KYGV+ DR DK AVG+++K E+ KH SQ+DYS+GFGG++GV+K++ DK+A+G+++K ETE
Sbjct: 123 KYGVERDRADKSAVGFDYKGEVEKHTSQKDYSRGFGGRYGVEKDKWDKAALGYDYKGETE 182
Query: 603 KHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKE 704
KH SQ+DY+KGFGG+YG+Q DR DKSAVG+ E
Sbjct: 183 KHESQRDYAKGFGGQYGIQKDRVDKSAVGFNEME 216
Score = 178 bits (451), Expect = 2e-44
Identities = 78/123 (63%), Positives = 106/123 (86%)
Frame = +3
Query: 3 MDKCAVGNDYVAAVDKHTSQKDYSQGFGGKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDY 182
MDK AVG++YVA V+KH+SQ D ++GFGGKYGV+ DR DKSA G++Y+ EV+KH SQ+DY
Sbjct: 94 MDKSAVGHEYVAEVEKHSSQTDAAKGFGGKYGVERDRADKSAVGFDYKGEVEKHTSQKDY 153
Query: 183 SKGFGGKYGVQKDRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWE 362
S+GFGG+YGV+KD+ DKAA+G+++K E EKH SQ+DY++GFGG++G+QK+R DKSAVG+
Sbjct: 154 SRGFGGRYGVEKDKWDKAALGYDYKGETEKHESQRDYAKGFGGQYGIQKDRVDKSAVGFN 213
Query: 363 HKE 371
E
Sbjct: 214 EME 216
Score = 176 bits (445), Expect = 9e-44
Identities = 85/161 (52%), Positives = 121/161 (75%), Gaps = 4/161 (2%)
Frame = +3
Query: 336 QDKSAVGWEH----KEETEKHGSQQDYSKGFGGKYGVQTDRQDKCAVGWEHKEELGKHAS 503
Q ++ V EH K+E E S S G+GG++GV+ DR DK AVG E+ E+ KH+S
Sbjct: 56 QLRNKVSEEHDVLRKKEME---SGPKASHGYGGRFGVERDRMDKSAVGHEYVAEVEKHSS 112
Query: 504 QQDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQDKSA 683
Q D ++GFGGK+GV+++R DKSAVG+++K E EKH SQ+DYS+GFGG+YGV+ D+ DK+A
Sbjct: 113 QTDAAKGFGGKYGVERDRADKSAVGFDYKGEVEKHTSQKDYSRGFGGRYGVEKDKWDKAA 172
Query: 684 VGWEHKEEVGKHSSQTDQSKGFGGKFGVQSDRQDKSALGWD 806
+G+++K E KH SQ D +KGFGG++G+Q DR DKSA+G++
Sbjct: 173 LGYDYKGETEKHESQRDYAKGFGGQYGIQKDRVDKSAVGFN 213
>sp|P49710|HCLS1_MOUSE Hematopoietic lineage cell-specific protein (Hematopoietic
cell-specific LYN substrate 1) (LckBP1)
Length = 486
Score = 195 bits (496), Expect = 1e-49
Identities = 85/137 (62%), Positives = 117/137 (85%)
Frame = +3
Query: 72 SQGFGGKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDYSKGFGGKYGVQKDRQDKAAVGWE 251
S G+GG++GV+ DR DKSA G EY A+V+KH SQ D ++GFGGKYGV++DR DK+AVG++
Sbjct: 80 SHGYGGQFGVERDRMDKSAVGHEYVADVEKHSSQTDAARGFGGKYGVERDRADKSAVGFD 139
Query: 252 HKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYG 431
+K E+EKH+SQKDYS GFGG++GV+K+++DK+A+G+++K ETEKH SQ+DY+KGFGG+YG
Sbjct: 140 YKGEVEKHASQKDYSHGFGGRYGVEKDKRDKAALGYDYKGETEKHESQRDYAKGFGGQYG 199
Query: 432 VQTDRQDKCAVGWEHKE 482
+Q DR DK AVG+ E
Sbjct: 200 IQKDRVDKSAVGFNEME 216
Score = 191 bits (485), Expect = 2e-48
Identities = 101/217 (46%), Positives = 137/217 (63%), Gaps = 22/217 (10%)
Frame = +3
Query: 120 KSAAGWEYQAEVQKHGSQQDYSKGFGGKYGVQKDR------------------QDKAAVG 245
KS G + V+ G D F ++ R Q + V
Sbjct: 3 KSVVGHDVSVSVETQGDDWDTDPDFVNDISEKEQRWGAKTIEGSGRTEHINIHQLRNKVS 62
Query: 246 WEH----KAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKG 413
EH K ELE S S G+GG+FGV+++R DKSAVG E+ + EKH SQ D ++G
Sbjct: 63 EEHDILKKKELE---SGPKASHGYGGQFGVERDRMDKSAVGHEYVADVEKHSSQTDAARG 119
Query: 414 FGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEHKE 593
FGGKYGV+ DR DK AVG+++K E+ KHASQ+DYS GFGG++GV+K+++DK+A+G+++K
Sbjct: 120 FGGKYGVERDRADKSAVGFDYKGEVEKHASQKDYSHGFGGRYGVEKDKRDKAALGYDYKG 179
Query: 594 ETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKE 704
ETEKH SQ+DY+KGFGG+YG+Q DR DKSAVG+ E
Sbjct: 180 ETEKHESQRDYAKGFGGQYGIQKDRVDKSAVGFNEME 216
Score = 178 bits (452), Expect = 1e-44
Identities = 78/123 (63%), Positives = 106/123 (86%)
Frame = +3
Query: 3 MDKCAVGNDYVAAVDKHTSQKDYSQGFGGKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDY 182
MDK AVG++YVA V+KH+SQ D ++GFGGKYGV+ DR DKSA G++Y+ EV+KH SQ+DY
Sbjct: 94 MDKSAVGHEYVADVEKHSSQTDAARGFGGKYGVERDRADKSAVGFDYKGEVEKHASQKDY 153
Query: 183 SKGFGGKYGVQKDRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWE 362
S GFGG+YGV+KD++DKAA+G+++K E EKH SQ+DY++GFGG++G+QK+R DKSAVG+
Sbjct: 154 SHGFGGRYGVEKDKRDKAALGYDYKGETEKHESQRDYAKGFGGQYGIQKDRVDKSAVGFN 213
Query: 363 HKE 371
E
Sbjct: 214 EME 216
Score = 175 bits (443), Expect = 2e-43
Identities = 84/161 (52%), Positives = 121/161 (75%), Gaps = 4/161 (2%)
Frame = +3
Query: 336 QDKSAVGWEH----KEETEKHGSQQDYSKGFGGKYGVQTDRQDKCAVGWEHKEELGKHAS 503
Q ++ V EH K+E E S S G+GG++GV+ DR DK AVG E+ ++ KH+S
Sbjct: 56 QLRNKVSEEHDILKKKELE---SGPKASHGYGGQFGVERDRMDKSAVGHEYVADVEKHSS 112
Query: 504 QQDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQDKSA 683
Q D ++GFGGK+GV+++R DKSAVG+++K E EKH SQ+DYS GFGG+YGV+ D++DK+A
Sbjct: 113 QTDAARGFGGKYGVERDRADKSAVGFDYKGEVEKHASQKDYSHGFGGRYGVEKDKRDKAA 172
Query: 684 VGWEHKEEVGKHSSQTDQSKGFGGKFGVQSDRQDKSALGWD 806
+G+++K E KH SQ D +KGFGG++G+Q DR DKSA+G++
Sbjct: 173 LGYDYKGETEKHESQRDYAKGFGGQYGIQKDRVDKSAVGFN 213
>sp|Q6XPR3|RPTN_HUMAN Repetin
Length = 784
Score = 63.9 bits (154), Expect = 5e-10
Identities = 72/239 (30%), Positives = 112/239 (46%), Gaps = 22/239 (9%)
Frame = +3
Query: 144 QAEVQKHGSQQDYSKGFGGKYGV-QKDRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFG 320
Q QK GS S+ G + G Q DRQ +++ H + ++ +D S +G
Sbjct: 261 QTNQQKSGSYCGQSERLGQELGCGQTDRQGQSS----HYGQTDR----QDQSYHYG---- 308
Query: 321 VQKERQDKSAVGWEHKEETEKHGSQQDYSK----GFGGKYGVQTDRQDKCA-VGWEHKEE 485
Q +RQ +S+ H +T++ G YS+ G YG Q DR+ +C +++
Sbjct: 309 -QTDRQGQSS----HYSQTDRQGQSSHYSQPDRQGQSSHYG-QMDRKGQCYHYDQTNRQG 362
Query: 486 LGKHASQQDYSQGFGGKFGV-----------QKERQDKSAVGWEHKEETEKHGSQQDYS- 629
G H SQ + QG +G Q +RQD+S+ H +TE+ G YS
Sbjct: 363 QGSHYSQPN-RQGQSSHYGQPDTQDQSSHYGQTDRQDQSS----HYGQTERQGQSSHYSQ 417
Query: 630 ---KGFGGKYGVQTDRQDKSA-VGWEHKEEVGKHSSQTDQSKGFGGKFGVQSDRQDKSA 794
+G G YG QTDRQ +S+ G ++ H QTD+ +G +G Q+DRQ +S+
Sbjct: 418 MDRQGQGSHYG-QTDRQGQSSHYGQPDRQGQNSHYGQTDR-QGQSSHYG-QTDRQGQSS 473
Score = 59.3 bits (142), Expect = 1e-08
Identities = 81/254 (31%), Positives = 117/254 (46%), Gaps = 6/254 (2%)
Frame = +3
Query: 51 HTSQKDYSQGFGGKYGVQSDRKDKSAAGWEYQAEVQ-KHGSQQDYSKGFGGKYGVQKDRQ 227
H Q D +Q YG Q+DR+D+S+ + + + Q H SQ D +G G YG Q DRQ
Sbjct: 378 HYGQPD-TQDQSSHYG-QTDRQDQSSHYGQTERQGQSSHYSQMD-RQGQGSHYG-QTDRQ 433
Query: 228 DKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYS 407
+++ H Q D QG +G Q +RQ +S+ H +T++ G YS
Sbjct: 434 GQSS-----------HYGQPD-RQGQNSHYG-QTDRQGQSS----HYGQTDRQGQSSHYS 476
Query: 408 ----KGFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKS-A 572
+G YG + DRQD+ H Q D QG +G Q +RQ +S
Sbjct: 477 QPDKQGQSSHYG-KIDRQDQ-----------SYHYGQPD-GQGQSSHYG-QTDRQGQSFH 522
Query: 573 VGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGKHSSQTDQSKGFG 752
G ++ H SQ D +G YG QTDRQ +S+ H QTD+ +G
Sbjct: 523 YGQPDRQGQSSHYSQMD-RQGQSSHYG-QTDRQGQSS-----------HYGQTDR-QGQS 568
Query: 753 GKFGVQSDRQDKSA 794
+G Q+DRQ +S+
Sbjct: 569 YHYG-QTDRQGQSS 581
>sp|Q86YZ3|HORN_HUMAN Hornerin
Length = 2850
Score = 53.9 bits (128), Expect = 5e-07
Identities = 59/251 (23%), Positives = 88/251 (35%), Gaps = 12/251 (4%)
Frame = +3
Query: 36 AAVDKHTSQKDYSQGFG--GKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDYSKGFG--GK 203
++ +H S +S G+G G QS R ++ + + +HGS S G G G
Sbjct: 1648 SSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGS 1707
Query: 204 YGVQKDRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAV------GWEH 365
Q + + G H + +H S G G + R S+V G H
Sbjct: 1708 GSGQSPSRGRHGSGLGHSSSHGQHGS----GSGRSSSRGPYESRSGHSSVFGQHESGSGH 1763
Query: 366 KEETEKHGSQQDY--SKGFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKF 539
+HGS + S+G G Q+ D+ G+H S S +G
Sbjct: 1764 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYG--- 1820
Query: 540 GVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGKH 719
+ G +HGS +S +G Q S GW G+H
Sbjct: 1821 --------QQGSGSGQSPSRGRHGSGSGHSSSYG---------QHGSGSGWSSSS--GRH 1861
Query: 720 SSQTDQSKGFG 752
S + QS GFG
Sbjct: 1862 GSGSGQSSGFG 1872
Score = 51.2 bits (121), Expect = 3e-06
Identities = 58/251 (23%), Positives = 86/251 (34%), Gaps = 12/251 (4%)
Frame = +3
Query: 36 AAVDKHTSQKDYSQGFG--GKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDYSKGFG--GK 203
++ +H S +S G+G G QS R ++ + + +HGS S G G G
Sbjct: 1178 SSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGS 1237
Query: 204 YGVQKDRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAV------GWEH 365
+ + G H + +H S G G + R S+V G H
Sbjct: 1238 GSGHSPSRGRHGSGLGHSSSHGQHGS----GSGRSSSRGPYESRSGHSSVFGQHESGSGH 1293
Query: 366 KEETEKHGSQQDY--SKGFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKF 539
+HGS + S+G G Q+ D+ G S S G+G
Sbjct: 1294 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYG--- 1350
Query: 540 GVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGKH 719
+ G +HGS +S +G Q S GW G+H
Sbjct: 1351 --------RHGAGSGQSPSRGRHGSGSGHSSSYG---------QHGSGSGWSSSS--GRH 1391
Query: 720 SSQTDQSKGFG 752
S + QS GFG
Sbjct: 1392 GSGSGQSSGFG 1402
Score = 50.8 bits (120), Expect = 4e-06
Identities = 65/266 (24%), Positives = 90/266 (33%), Gaps = 20/266 (7%)
Frame = +3
Query: 21 GNDYVAAVDKHTSQKDYSQGFGGKYGV-QSDRKDKSAAGWEYQAEVQKHGS--------- 170
G+ + ++ H S S GFG K G QS + +G + + +KHGS
Sbjct: 681 GSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSE 740
Query: 171 QQDYSKGFGGKYGV------QKDRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQKE 332
Q S G YG Q + G H +H S +S G
Sbjct: 741 QHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQH---GSG 797
Query: 333 RQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQDKCAVGWEHKEELGKHAS--Q 506
S+ G + G Q + G G Y + H G+ +S Q
Sbjct: 798 TSCSSSCGHYESGSGQASGFGQ-HESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQ 856
Query: 507 QDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFG--GKYGVQTDRQDKS 680
D S G +G Q +SA H +HGS S G G G Q+ +
Sbjct: 857 HDSSSGQSSSYG-----QHESAS--HHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRH 909
Query: 681 AVGWEHKEEVGKHSSQTDQSKGFGGK 758
G G+H S + QS GFG K
Sbjct: 910 GSGSGRSSSSGRHGSGSGQSSGFGHK 935
Score = 50.8 bits (120), Expect = 4e-06
Identities = 58/251 (23%), Positives = 87/251 (34%), Gaps = 12/251 (4%)
Frame = +3
Query: 36 AAVDKHTSQKDYSQGFG--GKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDYSKGFG--GK 203
++ +H S +S G+G G QS R ++ + + +HGS S G G G
Sbjct: 2118 SSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGS 2177
Query: 204 YGVQKDRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAV------GWEH 365
+ + G H + +H S G G + R S+V G H
Sbjct: 2178 GSGHSPSRGRHGSGSGHSSSHGQHGS----GSGRSSSRGPYESRSGHSSVFGQHESGSGH 2233
Query: 366 KEETEKHGSQQDY--SKGFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKF 539
+HGS + S+G G Q+ D+ G+H S S +G
Sbjct: 2234 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYG--- 2290
Query: 540 GVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGKH 719
+ G +HGS +S +G Q S GW G+H
Sbjct: 2291 --------QQGSGSGQSPSRGRHGSGSGHSSSYG---------QHGSGSGWSSSS--GRH 2331
Query: 720 SSQTDQSKGFG 752
S + QS GFG
Sbjct: 2332 GSGSGQSSGFG 2342
Score = 49.7 bits (117), Expect = 1e-05
Identities = 62/260 (23%), Positives = 96/260 (36%), Gaps = 13/260 (5%)
Frame = +3
Query: 24 NDYVAAVDKHTSQKDYSQGFG--GKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDYSKGFG 197
+++ + +H S +S G G G QS R ++ + + +HGS S G
Sbjct: 472 SEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHS 531
Query: 198 GKYGVQKDRQDKAAVGWEHKAELEKHSSQKDYSQGFG--GKFGVQKERQDKSAVGWEHKE 371
++G + + G H++ + SS + G G G + S+ G H+E
Sbjct: 532 -RHGSGSGQSPSPSRG-RHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSS-GLGHQE 588
Query: 372 ETE-------KHGSQQDYSKGFGGKYGVQTDRQDKCAVGWEHKEELGKHA--SQQDYSQG 524
+HGS +S G ++G + + C G+H S Q S G
Sbjct: 589 SRSGQSSGYGQHGSSSGHSSTHG-QHGSTSGQSSSC----------GQHGATSGQSSSHG 637
Query: 525 FGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKE 704
G Q R + G +HGS +S +G Q S GW
Sbjct: 638 QHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYG---------QHGSGSGWSSSN 688
Query: 705 EVGKHSSQTDQSKGFGGKFG 764
G H S + QS GFG K G
Sbjct: 689 --GPHGSVSGQSSGFGHKSG 706
Score = 43.5 bits (101), Expect = 7e-04
Identities = 58/252 (23%), Positives = 83/252 (32%), Gaps = 8/252 (3%)
Frame = +3
Query: 21 GNDYVAAVDKHTSQKDYSQGFGGKYGV--QSDRKDKSAAGWEYQAEVQKHGSQ--QDYSK 188
G+ Y + + S + GFG QS K +G + + +HGS Q S
Sbjct: 328 GSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSS 387
Query: 189 GFGGKYGVQKDRQDKAAVGWEHKAELEKHSSQKDYSQGFG--GKFGVQKERQDKSAVGWE 362
G G Q + H + +HSS S G G G Q + G+
Sbjct: 388 GQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFG 447
Query: 363 HKEETEKHGSQQDYSKGFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFG--GK 536
+ + S YS GFG EH +H S +S G G G
Sbjct: 448 RSSSSGPYVSGSGYSSGFGHHESSS-----------EHSSGYTQHGSGSGHSSGHGQHGS 496
Query: 537 FGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGK 716
Q R ++ +HGS S G ++G S G G+
Sbjct: 497 RSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHS-RHG--------SGSGQSPSPSRGR 547
Query: 717 HSSQTDQSKGFG 752
H S + QS +G
Sbjct: 548 HESGSRQSSSYG 559
Score = 40.0 bits (92), Expect = 0.008
Identities = 54/258 (20%), Positives = 79/258 (30%), Gaps = 14/258 (5%)
Frame = +3
Query: 21 GNDYVAAVDKHTSQKDYSQGFGGKYGV-QSDRKDKSAAGWEYQAEVQKHGS--------- 170
G+ ++ +H S S GFG K QS + +G + + ++HGS
Sbjct: 912 GSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSE 971
Query: 171 QQDYSKGFGGKYGVQKDRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSA 350
Q S G YG Q + ++G S + G +S
Sbjct: 972 QHGSSSGSSSSYG-QHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSG 1030
Query: 351 VGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFG 530
GW + GS G Q+ + H G+H S S G
Sbjct: 1031 SGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCG 1090
Query: 531 --GKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFG--GKYGVQTDRQDKSAVGWEH 698
G Q + G + GS S G G G Q+ + G
Sbjct: 1091 QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGR 1150
Query: 699 KEEVGKHSSQTDQSKGFG 752
G+H S +S GFG
Sbjct: 1151 SSSSGQHGSGLGESSGFG 1168
Score = 38.9 bits (89), Expect = 0.017
Identities = 55/276 (19%), Positives = 82/276 (29%), Gaps = 32/276 (11%)
Frame = +3
Query: 21 GNDYVAAVDKHTSQKDYSQGFGGKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDYSKGFGG 200
G+ + ++ +H S S GFG ++ W+ Q HGS G
Sbjct: 1851 GSGWSSSSGRHGSGSGQSSGFG----------HHESSSWQSSGYTQ-HGS----GSGHSS 1895
Query: 201 KYGVQKDRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWEHKEETE 380
Y R +++ G +H + SS + G G Q S G
Sbjct: 1896 SYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLG---HGQHGSGSGQSPSPSRG 1952
Query: 381 KHGSQQDYSKGFG--GKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFG-------- 530
+HGS S +G G + + G H LG S+ S G+G
Sbjct: 1953 RHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGH 2012
Query: 531 -------GKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFG---------------G 644
G Q + +HGS S G+G G
Sbjct: 2013 SSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG 2072
Query: 645 KYGVQTDRQDKSAVGWEHKEEVGKHSSQTDQSKGFG 752
Q+ + G G+H +S GFG
Sbjct: 2073 SGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFG 2108
Score = 37.7 bits (86), Expect = 0.038
Identities = 55/276 (19%), Positives = 81/276 (29%), Gaps = 32/276 (11%)
Frame = +3
Query: 21 GNDYVAAVDKHTSQKDYSQGFGGKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDYSKGFGG 200
G+ + ++ +H S S GFG ++ W+ Q HGS G
Sbjct: 1381 GSGWSSSSGRHGSGSGQSSGFG----------HHESSSWQSSGCTQ-HGS----GSGHSS 1425
Query: 201 KYGVQKDRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWEHKEETE 380
Y R +++ G H + SS + G G Q S G
Sbjct: 1426 SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLG---HGQHGSGSGQSPSPSRG 1482
Query: 381 KHGSQQDYSKGFG--GKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFG-------- 530
+HGS S + G + + G H LG S+ S G+G
Sbjct: 1483 RHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGH 1542
Query: 531 -------GKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFG---------------G 644
G Q + +HGS S G+G G
Sbjct: 1543 SSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG 1602
Query: 645 KYGVQTDRQDKSAVGWEHKEEVGKHSSQTDQSKGFG 752
Q+ + G G+H S +S GFG
Sbjct: 1603 SGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFG 1638
Score = 37.7 bits (86), Expect = 0.038
Identities = 55/276 (19%), Positives = 81/276 (29%), Gaps = 32/276 (11%)
Frame = +3
Query: 21 GNDYVAAVDKHTSQKDYSQGFGGKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDYSKGFGG 200
G+ + ++ +H S S GFG ++ W+ Q HGS G
Sbjct: 2321 GSGWSSSSGRHGSGSGQSSGFG----------HHESSSWQSSGYTQ-HGS----GSGHSS 2365
Query: 201 KYGVQKDRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWEHKEETE 380
Y R +++ G H + SS + G G Q S G
Sbjct: 2366 SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLG---HGQHGSGSGQSPSPSRG 2422
Query: 381 KHGSQQDYSKGFG--GKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFG-------- 530
+HGS S + G + + G H LG S+ S G+G
Sbjct: 2423 RHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGH 2482
Query: 531 -------GKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFG---------------G 644
G Q + +HGS S G+G G
Sbjct: 2483 SSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG 2542
Query: 645 KYGVQTDRQDKSAVGWEHKEEVGKHSSQTDQSKGFG 752
Q+ + G G+H S +S GFG
Sbjct: 2543 SGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFG 2578
>sp|P20930|FILA_HUMAN Filaggrin precursor
Length = 416
Score = 47.8 bits (112), Expect = 4e-05
Identities = 52/241 (21%), Positives = 89/241 (36%), Gaps = 3/241 (1%)
Frame = +3
Query: 72 SQGFGGKYGVQSDRKDKS--AAGWEYQAEVQKHGSQQDYSKGFGGKYGVQKDRQDKAAVG 245
S+ +G + SD + S + W A HGS Q+ + G + ++D+A G
Sbjct: 172 SRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRD--GSRHPRSHQEDRAGHG 229
Query: 246 WEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSK-GFGG 422
H A+ + S + GG+ Q +S+ G H ++ +S G G
Sbjct: 230 --HSADSSRQSGTRHTQTSSGGQ-AASSHEQARSSAGDRHGSHHQQSADSSRHSGIGHGQ 286
Query: 423 KYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEHKEETE 602
D + G + + G S G+ G ++ +SA G
Sbjct: 287 ASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARG-------- 338
Query: 603 KHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGKHSSQTDQSKGFGGKFGVQSDRQ 782
+ G +S F Y V T Q +S+ GW G+ S+ +Q++ + D Q
Sbjct: 339 RSGETSGHSGSF--LYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQD-SSRHSASQDGQ 395
Query: 783 D 785
D
Sbjct: 396 D 396
>sp|O76743|GLH4_CAEEL ATP-dependent RNA helicase glh-4 (Germline helicase 4)
Length = 1156
Score = 40.8 bits (94), Expect = 0.004
Identities = 69/277 (24%), Positives = 93/277 (33%), Gaps = 35/277 (12%)
Frame = +3
Query: 54 TSQKDYSQGFGGK-----YGVQSDRKDKSAAGWEYQAEVQKHGSQQDYSKGFGGKYGVQK 218
TS + GFGGK +G S S K G D S GFG
Sbjct: 374 TSGGTFGSGFGGKPTSTGFGAPSTTDSSSGQQTAGFGGASKPGFGGDSSTGFGSGL---- 429
Query: 219 DRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKF---GVQKERQDKSAVGWEHK--EETEK 383
KA G H+A ++S + GFGGK G ++SA G + K K
Sbjct: 430 ----KAGFGG-HRASTAENSGLPTETTGFGGKLPPAGFGASSSNESAFGQQSKGFGGATK 484
Query: 384 HGSQQDYSKGFG----GKYGVQ------TDRQDKCAVGWEH------KEELGKHASQQDY 515
+G D S FG G G Q TD K +G + K G
Sbjct: 485 NGFGGDSSNSFGKRDSGFGGPQDQGFGDTDAPSKSGLGSFNTGGGAVKSAFGAAGFGSSS 544
Query: 516 SQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWE 695
+ G G FG + Q + G E G + SK + D+
Sbjct: 545 NFGNGNTFGEPSDNQRGNWDGGERPRGCHNCGEEGHISK--------ECDKPKVPRFPCR 596
Query: 696 HKEEVGKHSSQTDQSK---------GFGGKFGVQSDR 779
+ E++G +S DQ + G G F V D+
Sbjct: 597 NCEQLGHFASDCDQPRVPRGPCRNCGIEGHFAVDCDQ 633
>sp|Q8VHD8|HORN_MOUSE Hornerin
Length = 2496
Score = 37.7 bits (86), Expect = 0.038
Identities = 48/250 (19%), Positives = 86/250 (34%), Gaps = 31/250 (12%)
Frame = +3
Query: 90 KYGVQSDRKDKSAAGWEYQAEVQKHGSQQDYSKGFGGKYGVQKDR--QDKAAVGWEHKA- 260
+YG Q S+ ++ ++ + Q + G GG G + R Q +++ G + +
Sbjct: 1810 RYGEQGSGSRNSSTQSRGRSTSRESSTSQRFGSGSGGSSGFSQGRSGQGRSSRGGQQGSF 1869
Query: 261 -----ELEKHSS---------QKDYSQGFGGKFGVQKERQDKSA------VGWEHKEETE 380
++H S Q +Y G G Q +S+ G
Sbjct: 1870 SGQTEGSQQHGSCCGQSSGYGQNEYGSGHSASSGQQGSHYSQSSSYGTHNSGGSPSSSQR 1929
Query: 381 KHGSQQDYSKGFG--GKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGG----KFG 542
HGS+ S G G G QT + G G++ + + G G ++G
Sbjct: 1930 GHGSRSGRSSGLGQYGSPSGQTSSSTRQGSGQGQASGSGRYGASSGQTSGCGSGQSTRYG 1989
Query: 543 VQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQT--DRQDKSAVGWEHKEEVGK 716
Q S+ + + + + Q Y G G G Q +S+ G + G+
Sbjct: 1990 EQGSGSRNSSTQSRGRSTSRESSTSQRYGSGSGESSGFSQGGSGQGRSSRGGQQGSFSGQ 2049
Query: 717 HSSQTDQSKG 746
S ++ G
Sbjct: 2050 TSGRSQHQSG 2059
Score = 37.0 bits (84), Expect = 0.064
Identities = 49/255 (19%), Positives = 87/255 (34%), Gaps = 32/255 (12%)
Frame = +3
Query: 78 GFGGKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDYSKGFGGKYGVQKDR--QDKAAVGWE 251
G +YG Q S+ ++ ++ + Q + G GG G + R Q +++ G +
Sbjct: 761 GQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRFGSGSGGSSGFSQGRSGQGRSSRGGQ 820
Query: 252 HKA------ELEKHSS---------QKDYSQGFGGKFGVQKERQDKSAVGWEH------- 365
+ ++H S Q +Y G G Q +S+ H
Sbjct: 821 QGSFSGQTEGSQQHGSCCGQSSGYGQNEYGSGHSASSGQQGSHYSQSSSYGTHNSGGSPS 880
Query: 366 KEETEKHGSQQDYSKGFG--GKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGG-- 533
HGS+ S G G G QT + G G++ + + G G
Sbjct: 881 SRPAGGHGSRSGRSSGLGQYGSPSGQTSSSTRQGSGQGQASGSGRYGASSGQTSGCGSGQ 940
Query: 534 --KFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQT--DRQDKSAVGWEHK 701
++G Q S+ + + + + Q Y G G G Q +S+ G +
Sbjct: 941 STRYGEQGSGSRNSSTQSRGRSTSRESSTSQRYGSGSGESSGFSQGGSGQGRSSRGGQQG 1000
Query: 702 EEVGKHSSQTDQSKG 746
G+ S ++ G
Sbjct: 1001 SFSGQTSGRSQHQSG 1015
Score = 35.8 bits (81), Expect = 0.14
Identities = 50/267 (18%), Positives = 82/267 (30%), Gaps = 36/267 (13%)
Frame = +3
Query: 60 QKDYSQGFGGKYGVQSDRKDKSAA------GWEYQAEVQKHGSQQDYSKGFG--GKYGVQ 215
Q +Y G G Q +S++ G + + HGS+ S G G G Q
Sbjct: 498 QNEYGSGHSASSGQQGSHYSQSSSYGTHNSGGSPSSSQRGHGSRSGRSSGLGQYGSPSGQ 557
Query: 216 KDRQDKAAVGWEHKAELEKHSSQKDYSQGFGG----KFGVQKERQDKSAVGWEHKEETEK 383
+ G + ++ + + G G ++G Q S+ + + +
Sbjct: 558 TSSSTRQGSGQGQASGSGRYGASSGQTSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRE 617
Query: 384 HGSQQDYSKGFG---------------------GKYGVQTDRQDKCAVGWEHKEELGKH- 497
+ Q Y G G G + QT + + G H G+
Sbjct: 618 SSTSQRYGSGSGESSGFSQGGSGQGRSSRGGQQGSFSGQTSGRSQHQSGSRHGSGSGQFP 677
Query: 498 -ASQQDYSQGFGGKFGVQKE-RQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQ 671
+ QQ G G S+ W H GS+Q G G QT
Sbjct: 678 ISGQQGSHHGHSSSSGTHNSGSSQSSSTQWSHGS-----GSEQSSGLGHYGSTSGQTASS 732
Query: 672 DKSAVGWEHKEEVGKHSSQTDQSKGFG 752
+ G G+ + + Q+ G G
Sbjct: 733 TRQGSGQGQASGSGRCGASSGQTSGCG 759
Score = 35.8 bits (81), Expect = 0.14
Identities = 50/267 (18%), Positives = 82/267 (30%), Gaps = 36/267 (13%)
Frame = +3
Query: 60 QKDYSQGFGGKYGVQSDRKDKSAA------GWEYQAEVQKHGSQQDYSKGFG--GKYGVQ 215
Q +Y G G Q +S++ G + + HGS+ S G G G Q
Sbjct: 1891 QNEYGSGHSASSGQQGSHYSQSSSYGTHNSGGSPSSSQRGHGSRSGRSSGLGQYGSPSGQ 1950
Query: 216 KDRQDKAAVGWEHKAELEKHSSQKDYSQGFGG----KFGVQKERQDKSAVGWEHKEETEK 383
+ G + ++ + + G G ++G Q S+ + + +
Sbjct: 1951 TSSSTRQGSGQGQASGSGRYGASSGQTSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRE 2010
Query: 384 HGSQQDYSKGFG---------------------GKYGVQTDRQDKCAVGWEHKEELGKH- 497
+ Q Y G G G + QT + + G H G+
Sbjct: 2011 SSTSQRYGSGSGESSGFSQGGSGQGRSSRGGQQGSFSGQTSGRSQHQSGSRHGSGSGQFP 2070
Query: 498 -ASQQDYSQGFGGKFGVQKE-RQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQ 671
+ QQ G G S+ W H GS+Q G G QT
Sbjct: 2071 ISGQQGSHHGHSSSSGTHNSGSSQSSSTQWSHGS-----GSEQSSGLGHYGSTSGQTASS 2125
Query: 672 DKSAVGWEHKEEVGKHSSQTDQSKGFG 752
+ G G+ + + Q+ G G
Sbjct: 2126 TRQGSGQGQASGSGRCGASSGQTSGCG 2152
Score = 35.4 bits (80), Expect = 0.19
Identities = 56/282 (19%), Positives = 97/282 (34%), Gaps = 37/282 (13%)
Frame = +3
Query: 57 SQKDYSQGFGGKYGVQSDRKDKSAAGWEYQAEVQKHGS---------QQDYSKGFGGKYG 209
SQ QG + G Q +++ ++Q+ +HGS QQ G G
Sbjct: 984 SQGGSGQGRSSRGGQQGSFSGQTSGRSQHQSG-SRHGSGSGQFPISGQQGSHHGHSSSSG 1042
Query: 210 VQKDRQDKAA-VGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKH 386
+++ W H + E+ S Y G Q + G + +
Sbjct: 1043 THNSGSSQSSSTQWSHGSGSEQSSGLGHYGSTSG-----QTASSTRQGSGQGQASGSGRC 1097
Query: 387 GSQQDYSKGFGG----KYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKE 554
G+ + G G +YG Q + + + ++ Q + G GG G +
Sbjct: 1098 GASSGQTSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRFGSGSGGSSGFSQG 1157
Query: 555 R--QDKSAVGWEH------KEETEKHGS---------QQDYSKGFGGKYGVQTDRQDKSA 683
R Q +S+ G + E +++HGS Q +Y G G Q +S+
Sbjct: 1158 RSGQGRSSRGGQQGSFSGQTEGSQQHGSCCGQSSGYGQNEYGSGHSASSGQQGSHYSQSS 1217
Query: 684 VGWEHKEEVGK------HSSQTDQSKGFGGKFGVQSDRQDKS 791
H H S++ +S G G++G S + S
Sbjct: 1218 SYGTHNSGGSPSSSQRGHGSRSGRSSGL-GQYGSPSGQTSSS 1258
Score = 35.4 bits (80), Expect = 0.19
Identities = 55/283 (19%), Positives = 84/283 (29%), Gaps = 36/283 (12%)
Frame = +3
Query: 60 QKDYSQGFGGKYGVQSDRKDKSAA------GWEYQAEVQKHGSQQDYSKGFG-------- 197
Q +Y G G Q +S++ G + + HGS+ S G G
Sbjct: 1543 QNEYGSGHSASSGQQGSHYSQSSSYGTHNSGGSPSSSQRGHGSRSGRSSGLGQYGSPSGQ 1602
Query: 198 -----------------GKYGVQKDRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQ 326
G+YG + G + + S+ +Q G +
Sbjct: 1603 TSSSTRQGSGQGQASGSGRYGASSGQTSGCGSGQPTRYGEQGSGSRNSSTQSRGRSTSRE 1662
Query: 327 KERQDKSAVGWEHKEETEKHGSQQDYSK--GFGGKYGVQTDRQDKCAVGWEHKEELGKH- 497
+ G + GS Q S G G + QT + + G H G+
Sbjct: 1663 SSTSQRCGSGSGESSGFSQGGSGQGRSSRGGQQGSFSGQTSGRSQHQSGSRHGSGSGQFP 1722
Query: 498 -ASQQDYSQGFGGKFGVQKE-RQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQ 671
+ QQ G G S+ W H GS+Q G G QT
Sbjct: 1723 ISGQQGSHHGHSSSSGTHNSGSSQSSSTQWSHGS-----GSEQSSGLGHYGSTSGQTASS 1777
Query: 672 DKSAVGWEHKEEVGKHSSQTDQSKGFGGKFGVQSDRQDKSALG 800
+ G G+ + + Q+ G G QS R + G
Sbjct: 1778 TRQGSGQGQASGSGRCGASSGQTSGCGSD---QSTRYGEQGSG 1817
Score = 35.4 bits (80), Expect = 0.19
Identities = 56/282 (19%), Positives = 97/282 (34%), Gaps = 37/282 (13%)
Frame = +3
Query: 57 SQKDYSQGFGGKYGVQSDRKDKSAAGWEYQAEVQKHGS---------QQDYSKGFGGKYG 209
SQ QG + G Q +++ ++Q+ +HGS QQ G G
Sbjct: 1680 SQGGSGQGRSSRGGQQGSFSGQTSGRSQHQSG-SRHGSGSGQFPISGQQGSHHGHSSSSG 1738
Query: 210 VQKDRQDKAA-VGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKH 386
+++ W H + E+ S Y G Q + G + +
Sbjct: 1739 THNSGSSQSSSTQWSHGSGSEQSSGLGHYGSTSG-----QTASSTRQGSGQGQASGSGRC 1793
Query: 387 GSQQDYSKGFGG----KYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKE 554
G+ + G G +YG Q + + + ++ Q + G GG G +
Sbjct: 1794 GASSGQTSGCGSDQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRFGSGSGGSSGFSQG 1853
Query: 555 R--QDKSAVGWEH------KEETEKHGS---------QQDYSKGFGGKYGVQTDRQDKSA 683
R Q +S+ G + E +++HGS Q +Y G G Q +S+
Sbjct: 1854 RSGQGRSSRGGQQGSFSGQTEGSQQHGSCCGQSSGYGQNEYGSGHSASSGQQGSHYSQSS 1913
Query: 684 VGWEHKEEVGK------HSSQTDQSKGFGGKFGVQSDRQDKS 791
H H S++ +S G G++G S + S
Sbjct: 1914 SYGTHNSGGSPSSSQRGHGSRSGRSSGL-GQYGSPSGQTSSS 1954
Score = 35.0 bits (79), Expect = 0.24
Identities = 56/282 (19%), Positives = 97/282 (34%), Gaps = 37/282 (13%)
Frame = +3
Query: 57 SQKDYSQGFGGKYGVQSDRKDKSAAGWEYQAEVQKHGS---------QQDYSKGFGGKYG 209
SQ QG + G Q +++ ++Q+ +HGS QQ G G
Sbjct: 1332 SQGGSGQGRSSRGGQQGSFSGQTSGRNQHQSG-SRHGSGSGQFPISGQQGSHHGHSSSSG 1390
Query: 210 VQKDRQDKAA-VGWEHKAELEKHSSQKDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKH 386
+++ W H + E+ S Y G Q + G + +
Sbjct: 1391 THNSGSSQSSSTQWSHGSGSEQSSGLGHYGSTSG-----QTASSTRQGSGQGQASGSGRC 1445
Query: 387 GSQQDYSKGFGG----KYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKE 554
G+ + G G +YG Q + + + ++ Q + G GG G +
Sbjct: 1446 GASSGQTSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRFGSGSGGSSGFSQG 1505
Query: 555 R--QDKSAVGWEH------KEETEKHGS---------QQDYSKGFGGKYGVQTDRQDKSA 683
R Q +S+ G + E +++HGS Q +Y G G Q +S+
Sbjct: 1506 RSGQGRSSRGGQQGSFSGQTEGSQQHGSCCGQSSGYGQNEYGSGHSASSGQQGSHYSQSS 1565
Query: 684 VGWEHKEEVGK------HSSQTDQSKGFGGKFGVQSDRQDKS 791
H H S++ +S G G++G S + S
Sbjct: 1566 SYGTHNSGGSPSSSQRGHGSRSGRSSGL-GQYGSPSGQTSSS 1606
Score = 34.7 bits (78), Expect = 0.32
Identities = 51/267 (19%), Positives = 80/267 (29%), Gaps = 36/267 (13%)
Frame = +3
Query: 60 QKDYSQGFGGKYGVQSDRKDKSAA------GWEYQAEVQKHGSQQDYSKGFG-------- 197
Q +Y G G Q +S++ G + + HGS+ S G G
Sbjct: 1195 QNEYGSGHSASSGQQGSHYSQSSSYGTHNSGGSPSSSQRGHGSRSGRSSGLGQYGSPSGQ 1254
Query: 198 -----------------GKYGVQKDRQDKAAVGWEHKAELEKHSSQKDYSQGFGGKFGVQ 326
G+YG + G + + S+ +Q G +
Sbjct: 1255 TSSSTRQGSGQGQASGSGRYGASSGQTSGCRSGQSTRYGGQGSGSRNSSTQSRGRSTSRE 1314
Query: 327 KERQDKSAVGWEHKEETEKHGSQQDYSK--GFGGKYGVQTDRQDKCAVGWEHKEELGKH- 497
+ G + GS Q S G G + QT +++ G H G+
Sbjct: 1315 SSTSQRYGSGSGESSGFSQGGSGQGRSSRGGQQGSFSGQTSGRNQHQSGSRHGSGSGQFP 1374
Query: 498 -ASQQDYSQGFGGKFGVQKE-RQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQ 671
+ QQ G G S+ W H GS+Q G G QT
Sbjct: 1375 ISGQQGSHHGHSSSSGTHNSGSSQSSSTQWSHGS-----GSEQSSGLGHYGSTSGQTASS 1429
Query: 672 DKSAVGWEHKEEVGKHSSQTDQSKGFG 752
+ G G+ + + Q+ G G
Sbjct: 1430 TRQGSGQGQASGSGRCGASSGQTSGCG 1456
Score = 34.7 bits (78), Expect = 0.32
Identities = 48/254 (18%), Positives = 86/254 (33%), Gaps = 31/254 (12%)
Frame = +3
Query: 78 GFGGKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDYSKGFGGKYGVQKDR--QDKAAVGWE 251
G +YG Q S+ ++ ++ + Q + G GG G + R Q +++ G +
Sbjct: 1458 GQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRFGSGSGGSSGFSQGRSGQGRSSRGGQ 1517
Query: 252 HKA------ELEKHSS---------QKDYSQGFGGKFGVQKERQDKSA------VGWEHK 368
+ ++H S Q +Y G G Q +S+ G
Sbjct: 1518 QGSFSGQTEGSQQHGSCCGQSSGYGQNEYGSGHSASSGQQGSHYSQSSSYGTHNSGGSPS 1577
Query: 369 EETEKHGSQQDYSKGFG--GKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGG--- 533
HGS+ S G G G QT + G G++ + + G G
Sbjct: 1578 SSQRGHGSRSGRSSGLGQYGSPSGQTSSSTRQGSGQGQASGSGRYGASSGQTSGCGSGQP 1637
Query: 534 -KFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQT--DRQDKSAVGWEHKE 704
++G Q S+ + + + + Q G G G Q +S+ G +
Sbjct: 1638 TRYGEQGSGSRNSSTQSRGRSTSRESSTSQRCGSGSGESSGFSQGGSGQGRSSRGGQQGS 1697
Query: 705 EVGKHSSQTDQSKG 746
G+ S ++ G
Sbjct: 1698 FSGQTSGRSQHQSG 1711
Score = 34.3 bits (77), Expect = 0.42
Identities = 48/254 (18%), Positives = 85/254 (33%), Gaps = 31/254 (12%)
Frame = +3
Query: 78 GFGGKYGVQSDRKDKSAAGWEYQAEVQKHGSQQDYSKGFGGKYGVQKDR--QDKAAVGWE 251
G +YG Q S+ ++ ++ + Q + G GG G + R Q +++ G +
Sbjct: 1110 GQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRFGSGSGGSSGFSQGRSGQGRSSRGGQ 1169
Query: 252 HKA------ELEKHSS---------QKDYSQGFGGKFGVQKERQDKSA------VGWEHK 368
+ ++H S Q +Y G G Q +S+ G
Sbjct: 1170 QGSFSGQTEGSQQHGSCCGQSSGYGQNEYGSGHSASSGQQGSHYSQSSSYGTHNSGGSPS 1229
Query: 369 EETEKHGSQQDYSKGFG--GKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGF----G 530
HGS+ S G G G QT + G G++ + + G
Sbjct: 1230 SSQRGHGSRSGRSSGLGQYGSPSGQTSSSTRQGSGQGQASGSGRYGASSGQTSGCRSGQS 1289
Query: 531 GKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQT--DRQDKSAVGWEHKE 704
++G Q S+ + + + + Q Y G G G Q +S+ G +
Sbjct: 1290 TRYGGQGSGSRNSSTQSRGRSTSRESSTSQRYGSGSGESSGFSQGGSGQGRSSRGGQQGS 1349
Query: 705 EVGKHSSQTDQSKG 746
G+ S + G
Sbjct: 1350 FSGQTSGRNQHQSG 1363
Score = 33.5 bits (75), Expect = 0.71
Identities = 58/293 (19%), Positives = 102/293 (34%), Gaps = 47/293 (16%)
Frame = +3
Query: 54 TSQKDYSQGFGGKYGVQ--SDRKDKSAAGWEYQAEVQKHGSQQDYSKGFGGKYGVQKDRQ 227
+ ++YS G + G S RK+ S G Q G Q +GFG + ++ +
Sbjct: 273 SGSQEYSSGSSEEPGFTHGSGRKNSSTCGKNGSYSGQSTGRHQ---QGFGSSHELESGQS 329
Query: 228 DKAAVGWEHKAELE----------KHSSQKDYSQGFG-----GKF---GVQKERQDKSAV 353
+A H + + S +K + G G GK+ Q +
Sbjct: 330 ITSANHGSHSNQSSCSGTRECGSSESSMKKTHVSGSGHSSSTGKYTSTSGQNYNSTRQGC 389
Query: 354 GWEHKEETEKHGSQQDYSKGFGG----KYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQ 521
G +E++G+ S G +YG Q + + + ++ Q +
Sbjct: 390 GQGKSSGSEQYGASSGQSSGCSSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQQFGS 449
Query: 522 GFGGKFGVQK--ERQDKSAVGWEH------KEETEKHGS---------QQDYSKGFGGKY 650
G G G + Q +S+ G + E +++HGS Q +Y G
Sbjct: 450 GSGRSSGFSQGGSGQGRSSRGGQQGSFSGQTEGSQQHGSCCGQSSGYGQNEYGSGHSASS 509
Query: 651 GVQTDRQDKSAVGWEHKEEVGK------HSSQTDQSKGFGGKFGVQSDRQDKS 791
G Q +S+ H H S++ +S G G++G S + S
Sbjct: 510 GQQGSHYSQSSSYGTHNSGGSPSSSQRGHGSRSGRSSGL-GQYGSPSGQTSSS 561
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 102,394,833
Number of Sequences: 369166
Number of extensions: 2357345
Number of successful extensions: 7743
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5785
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7585
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7763237265
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)