Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_G12
(791 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q92804|RBP56_HUMAN TATA-binding protein associated facto... 82 2e-15
sp|Q61545|EWS_MOUSE RNA-binding protein EWS 80 5e-15
sp|Q01844|EWS_HUMAN RNA-binding protein EWS (EWS oncogene) ... 79 1e-14
sp|P56959|FUS_MOUSE RNA-binding protein FUS (Pigpen protein) 69 1e-11
sp|P35637|FUS_HUMAN RNA-binding protein FUS (Oncogene FUS) ... 69 1e-11
sp|Q28009|FUS_BOVIN RNA-binding protein FUS (Pigpen protein) 69 1e-11
sp|Q27294|CAZ_DROME RNA-binding protein cabeza (Sarcoma-ass... 69 2e-11
sp|P53830|YN26_YEAST Hypothetical 32.3 kDa protein in SEC21... 51 4e-06
sp|O43120|UAP2_SCHPO Splicing factor U2AF-associated protein 2 48 3e-05
sp|Q08935|ROC1_NICSY 29 kDa ribonucleoprotein A, chloroplas... 46 1e-04
>sp|Q92804|RBP56_HUMAN TATA-binding protein associated factor 2N (RNA-binding protein 56)
(TAFII68) (TAF(II)68)
Length = 592
Score = 82.0 bits (201), Expect = 2e-15
Identities = 61/218 (27%), Positives = 89/218 (40%), Gaps = 4/218 (1%)
Frame = +1
Query: 52 QTGNQSEDGALRLNTVYVSNLPQNLDHEMLKTQFSKAGSIKLNSKSGMPMIWIF--KDRG 225
+T SE NT++V L + + + + F + G IK N K+G PMI ++ KD G
Sbjct: 221 RTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTG 280
Query: 226 VPKGDALVTYDSNSSASNAVSYFKDHDFNGRRIEVRIATNAERPILAPPSSXXXXXXXXX 405
PKG+A V++D SA A+ +F +F+G I+V AT
Sbjct: 281 KPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATR-------------------- 320
Query: 406 XXXXXXYKIESISRNNDYESDSYDWQKREDGGFNKQREFXXXXXXXXXXXXGPDWIC--G 579
R +R GG+ + F DW+C
Sbjct: 321 -------------RPEFMRGGGSGGGRRGRGGYRGRGGF----QGRGGDPKSGDWVCPNP 363
Query: 580 KCNNNNFSWRESCNRCQEPKAENAIEVHKQDRGRGLTG 693
C N NF+ R SCN+C EP+ E++ RGRG G
Sbjct: 364 SCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGG 401
>sp|Q61545|EWS_MOUSE RNA-binding protein EWS
Length = 655
Score = 80.5 bits (197), Expect = 5e-15
Identities = 63/222 (28%), Positives = 90/222 (40%), Gaps = 21/222 (9%)
Frame = +1
Query: 91 NTVYVSNLPQNLDHEMLKTQFSKAGSIKLNSKSGMPMIWIFKDR--GVPKGDALVTYDSN 264
+ +YV L N+ + L F + G +K+N ++G PMI I+ D+ G PKGDA V+Y+
Sbjct: 360 SAIYVQGLNDNVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDP 419
Query: 265 SSASNAVSYFKDHDFNGRRIEVRIA-----TNAERPILAPPSSXXXXXXXXXXXXXXXYK 429
+A AV +F DF G +++V +A N+ R + P
Sbjct: 420 PTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGMPpreGRGMPPPLRGGPGGPGGP 479
Query: 430 IESISRNNDYESDSYDWQKR--------EDGGFNKQREFXXXXXXXXXXXXGPDWICGK- 582
+ R D + R GG N Q DW C
Sbjct: 480 GGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHR-------------AGDWQCPNP 526
Query: 583 -CNNNNFSWRESCNRCQEPKAENAI----EVHKQDRGRGLTG 693
C N NF+WR CN+C+ PK E + DRGRG G
Sbjct: 527 GCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPG 568
>sp|Q01844|EWS_HUMAN RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint
region 1 protein)
Length = 656
Score = 79.3 bits (194), Expect = 1e-14
Identities = 63/222 (28%), Positives = 90/222 (40%), Gaps = 21/222 (9%)
Frame = +1
Query: 91 NTVYVSNLPQNLDHEMLKTQFSKAGSIKLNSKSGMPMIWIFKDR--GVPKGDALVTYDSN 264
+ +YV L ++ + L F + G +K+N ++G PMI I+ D+ G PKGDA V+Y+
Sbjct: 361 SAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDP 420
Query: 265 SSASNAVSYFKDHDFNGRRIEVRIA-----TNAERPILAPPSSXXXXXXXXXXXXXXXYK 429
+A AV +F DF G +++V +A N+ R L P
Sbjct: 421 PTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPpreGRGMPPPLRGGPGGPGGP 480
Query: 430 IESISRNNDYESDSYDWQKR--------EDGGFNKQREFXXXXXXXXXXXXGPDWICGK- 582
+ R D + R GG N Q DW C
Sbjct: 481 GGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHR-------------AGDWQCPNP 527
Query: 583 -CNNNNFSWRESCNRCQEPKAENAI----EVHKQDRGRGLTG 693
C N NF+WR CN+C+ PK E + DRGRG G
Sbjct: 528 GCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPG 569
>sp|P56959|FUS_MOUSE RNA-binding protein FUS (Pigpen protein)
Length = 518
Score = 69.3 bits (168), Expect = 1e-11
Identities = 51/189 (26%), Positives = 75/189 (39%), Gaps = 4/189 (2%)
Frame = +1
Query: 91 NTVYVSNLPQNLDHEMLKTQFSKAGSIKLNSKSGMPMIWIFKDR--GVPKGDALVTYDSN 264
NT++V L +N+ E + F + G IK N K+G PMI ++ DR G KG+A V++D
Sbjct: 278 NTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDP 337
Query: 265 SSASNAVSYFKDHDFNGRRIEVRIATNAERPILAPPSSXXXXXXXXXXXXXXXYKIESIS 444
SA A+ +F +F+G ++++ R
Sbjct: 338 PSAKAAIDWFDGKEFSGN--PIKVSFATRRADFNRGGGNGRGGR---------------G 380
Query: 445 RNNDYESDSYDWQKREDGGFNKQREFXXXXXXXXXXXXGPDWICGK--CNNNNFSWRESC 618
R Y GG + F DW C C N NFSWR C
Sbjct: 381 RGGPMGRGGYGGGGSGGGG---RGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNEC 437
Query: 619 NRCQEPKAE 645
N+C+ PK +
Sbjct: 438 NQCKAPKPD 446
>sp|P35637|FUS_HUMAN RNA-binding protein FUS (Oncogene FUS) (Oncogene TLS) (Translocated
in liposarcoma protein) (POMp75) (75 kDa DNA-pairing
protein)
Length = 526
Score = 69.3 bits (168), Expect = 1e-11
Identities = 51/189 (26%), Positives = 75/189 (39%), Gaps = 4/189 (2%)
Frame = +1
Query: 91 NTVYVSNLPQNLDHEMLKTQFSKAGSIKLNSKSGMPMIWIFKDR--GVPKGDALVTYDSN 264
NT++V L +N+ E + F + G IK N K+G PMI ++ DR G KG+A V++D
Sbjct: 285 NTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDP 344
Query: 265 SSASNAVSYFKDHDFNGRRIEVRIATNAERPILAPPSSXXXXXXXXXXXXXXXYKIESIS 444
SA A+ +F +F+G ++++ R
Sbjct: 345 PSAKAAIDWFDGKEFSGN--PIKVSFATRRADFNRGGGNGRGGR---------------G 387
Query: 445 RNNDYESDSYDWQKREDGGFNKQREFXXXXXXXXXXXXGPDWICGK--CNNNNFSWRESC 618
R Y GG + F DW C C N NFSWR C
Sbjct: 388 RGGPMGRGGYGGGGSGGGG---RGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNEC 444
Query: 619 NRCQEPKAE 645
N+C+ PK +
Sbjct: 445 NQCKAPKPD 453
>sp|Q28009|FUS_BOVIN RNA-binding protein FUS (Pigpen protein)
Length = 512
Score = 69.3 bits (168), Expect = 1e-11
Identities = 51/189 (26%), Positives = 75/189 (39%), Gaps = 4/189 (2%)
Frame = +1
Query: 91 NTVYVSNLPQNLDHEMLKTQFSKAGSIKLNSKSGMPMIWIFKDR--GVPKGDALVTYDSN 264
NT++V L +N+ E + F + G IK N K+G PMI ++ DR G KG+A V++D
Sbjct: 271 NTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDP 330
Query: 265 SSASNAVSYFKDHDFNGRRIEVRIATNAERPILAPPSSXXXXXXXXXXXXXXXYKIESIS 444
SA A+ +F +F+G ++++ R
Sbjct: 331 PSAKAAIDWFDGKEFSGN--PIKVSFATRRADFNRGGGNGRGGR---------------G 373
Query: 445 RNNDYESDSYDWQKREDGGFNKQREFXXXXXXXXXXXXGPDWICGK--CNNNNFSWRESC 618
R Y GG + F DW C C N NFSWR C
Sbjct: 374 RGGPMGRGGYGGGGSGGGG---RGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNEC 430
Query: 619 NRCQEPKAE 645
N+C+ PK +
Sbjct: 431 NQCKAPKPD 439
>sp|Q27294|CAZ_DROME RNA-binding protein cabeza (Sarcoma-associated RNA-binding fly
homolog) (P19)
Length = 399
Score = 68.6 bits (166), Expect = 2e-11
Identities = 32/96 (33%), Positives = 57/96 (59%), Gaps = 2/96 (2%)
Frame = +1
Query: 58 GNQSEDGALRLNTVYVSNLPQNLDHEMLKTQFSKAGSIKLNSKSGMPMIWIFKDR--GVP 231
G+ D + +T++VS + + + ++T F G IK + ++ P IW++K++ G
Sbjct: 109 GSGGNDMITQEDTIFVSGMDPSTTEQDIETHFGAIGIIKKDKRTMKPKIWLYKNKETGAS 168
Query: 232 KGDALVTYDSNSSASNAVSYFKDHDFNGRRIEVRIA 339
KG+A VTYD ++A +A+ +F DFNG I+V +A
Sbjct: 169 KGEATVTYDDTNAAQSAIEWFDGRDFNGNAIKVSLA 204
Score = 49.7 bits (117), Expect = 9e-06
Identities = 16/28 (57%), Positives = 20/28 (71%)
Frame = +1
Query: 565 DWICGKCNNNNFSWRESCNRCQEPKAEN 648
DW C CNN NF+WR CNRC+ PK ++
Sbjct: 278 DWKCNSCNNTNFAWRNECNRCKTPKGDD 305
>sp|P53830|YN26_YEAST Hypothetical 32.3 kDa protein in SEC21-MRPL10 intergenic region
Length = 285
Score = 50.8 bits (120), Expect = 4e-06
Identities = 33/99 (33%), Positives = 51/99 (51%), Gaps = 2/99 (2%)
Frame = +1
Query: 49 LQTGNQSEDGALRLNTVYVSNLPQN-LDHEMLKTQFSKAGSIKLNSKSGMPMIWIF-KDR 222
LQ + A + ++Y+S LP + E L QF K G I+ N + G P+ ++ D+
Sbjct: 31 LQKRELEYNNASKNTSIYISGLPTDKTTKEGLTEQFCKYGMIRTN-RDGEPLCKLYVNDK 89
Query: 223 GVPKGDALVTYDSNSSASNAVSYFKDHDFNGRRIEVRIA 339
G KGDAL+TY S + A+ + F G++I V A
Sbjct: 90 GAFKGDALITYSKEESVTLAIEMMNESIFLGKQIRVERA 128
>sp|O43120|UAP2_SCHPO Splicing factor U2AF-associated protein 2
Length = 367
Score = 48.1 bits (113), Expect = 3e-05
Identities = 28/85 (32%), Positives = 47/85 (55%), Gaps = 4/85 (4%)
Frame = +1
Query: 97 VYVSNLPQNLDHEMLKTQFSKAGSIKLNSKSGMPMIWIFK-DRGVPKGDALVTYDSNSSA 273
VY+ LP ++ + ++ F K G I N +G P I I++ + G PKGDAL+ + + S
Sbjct: 112 VYIQGLPLDVTVDEIEEVFKKCGVIAKNIDNGTPRIKIYRTEDGTPKGDALIVFFRSESV 171
Query: 274 SNAVSYFKDHDF---NGRRIEVRIA 339
A F D +F +G+++ V+ A
Sbjct: 172 ELAEQLFDDTEFRYGSGQKMRVQKA 196
>sp|Q08935|ROC1_NICSY 29 kDa ribonucleoprotein A, chloroplast precursor (CP29A)
Length = 273
Score = 45.8 bits (107), Expect = 1e-04
Identities = 28/80 (35%), Positives = 41/80 (51%)
Frame = +1
Query: 91 NTVYVSNLPQNLDHEMLKTQFSKAGSIKLNSKSGMPMIWIFKDRGVPKGDALVTYDSNSS 270
N VYV NL +D + L+T FS+ G + +++K + +D G +G VTY S
Sbjct: 188 NRVYVGNLAWGVDQDALETLFSEQGKV-VDAK-----VVYDRDSGRSRGFGFVTYSSAEE 241
Query: 271 ASNAVSYFKDHDFNGRRIEV 330
+NA+ D NGR I V
Sbjct: 242 VNNAIESLDGVDLNGRAIRV 261
Score = 34.7 bits (78), Expect = 0.31
Identities = 22/88 (25%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Frame = +1
Query: 97 VYVSNLPQNLDHEMLKTQFSKAGSIKLNSKSGMPMIWIFKDR--GVPKGDALVTYDSNSS 270
++V NLP + D L F +AG+++ M+ + D+ G +G VT S
Sbjct: 89 IFVGNLPFSADSAALAELFERAGNVE--------MVEVIYDKLTGRSRGFGFVTMSSKEE 140
Query: 271 ASNAVSYFKDHDFNGRRIEVRIATNAER 354
A F ++ +GR + V E+
Sbjct: 141 VEAACQQFNGYELDGRALRVNSGPPPEK 168
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.316 0.134 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,698,017
Number of Sequences: 369166
Number of extensions: 1554589
Number of successful extensions: 4248
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4050
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4229
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7425705210
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)