Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_G05
(689 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O08547|SC221_MOUSE Vesicle trafficking protein SEC22b (S... 220 2e-57
sp|Q9Y7L0|SEC22_SCHPO Protein transport protein sec22 146 6e-35
sp|Q6C880|SEC22_YARLI Protein transport protein SEC22 137 2e-32
sp|Q94AU2|SC22_ARATH 25.3 kDa vesicle transport protein (At... 136 6e-32
sp|Q6CJA0|SEC22_KLULA Protein transport protein SEC22 127 3e-29
sp|Q74ZD2|SEC22_ASHGO Protein transport protein SEC22 127 4e-29
sp|Q6FWT0|SEC22_CANGA Protein transport protein SEC22 117 3e-26
sp|P22214|SEC22_YEAST Protein transport protein SEC22 (Prot... 109 8e-24
sp|Q9SIQ9|V712_ARATH Vesicle-associated membrane protein 71... 76 7e-14
sp|O49377|V711_ARATH Vesicle-associated membrane protein 71... 74 3e-13
>sp|O08547|SC221_MOUSE Vesicle trafficking protein SEC22b (SEC22 vesicle trafficking
protein-like 1)
sp|Q5RAI9|SC221_PONPY Vesicle trafficking protein SEC22b (SEC22 vesicle trafficking
protein-like 1)
sp|O75396|SC221_HUMAN Vesicle trafficking protein SEC22b (SEC22 vesicle trafficking
protein-like 1)
Length = 215
Score = 220 bits (561), Expect = 2e-57
Identities = 106/187 (56%), Positives = 140/187 (74%)
Frame = +1
Query: 64 RISDGLVLAASMQEDEKIIKSLNHYQCQAKQLLKKFNNLSPSVGSIESDSYMFHYFIDRE 243
R++DGL LAASMQEDE+ + L YQ QAKQL +K N SP+ ++E+ + FHY I++
Sbjct: 9 RVADGLPLAASMQEDEQSGRDLQQYQSQAKQLFRKLNEQSPTRCTLEAGAMTFHYIIEQG 68
Query: 244 VCCIILTEKEFSKKMAFAFLTDIMGEFYNEHGSKIGIVSRPYAFIEFDRYIQKAKKIYTD 423
VC ++L E F KK+AFA+L D+ EF +HG K+ VSRPY+FIEFD +IQK KK+Y D
Sbjct: 69 VCYLVLCEAAFPKKLAFAYLEDLHSEFDEQHGKKVPTVSRPYSFIEFDTFIQKTKKLYID 128
Query: 424 TRTSRNISQLNYELKDVQRIMVKNIDDVIQRGESLSILDDKLTNISSLSKRYRQDATYLN 603
+R RN+ +N EL+DVQRIMV NI++V+QRGE+LS LD K N+SSLSK+YRQDA YLN
Sbjct: 129 SRARRNLGSINTELQDVQRIMVANIEEVLQRGEALSALDSKANNLSSLSKKYRQDAKYLN 188
Query: 604 LKSIYVK 624
++S Y K
Sbjct: 189 MRSTYAK 195
>sp|Q9Y7L0|SEC22_SCHPO Protein transport protein sec22
Length = 209
Score = 146 bits (368), Expect = 6e-35
Identities = 73/186 (39%), Positives = 124/186 (66%), Gaps = 3/186 (1%)
Frame = +1
Query: 79 LVLAASMQEDEKIIKSLNHYQCQAKQLLKKFNNLSPSVGSIESDSYMFHYFIDREVCCII 258
L LAAS+ +DE ++L ++ QAK +LK+ + S SIES Y FHY ID +C +
Sbjct: 7 LPLAASV-DDESTERNLESHKKQAKLILKRLSPTSEKRASIESGDYTFHYLIDNGICYLC 65
Query: 259 LTEKEFSKKMAFAFLTDIMGEFYNEHGSKI---GIVSRPYAFIEFDRYIQKAKKIYTDTR 429
+ E+ + +K+AF++L ++ GEF+N G + G+ RPYAF++FD ++QK+K++Y R
Sbjct: 66 ICEQSYPRKLAFSYLEELAGEFWNSFGEEALQPGL--RPYAFVQFDTFMQKSKRVYNTPR 123
Query: 430 TSRNISQLNYELKDVQRIMVKNIDDVIQRGESLSILDDKLTNISSLSKRYRQDATYLNLK 609
+ N+ +LN ELKDV R+M KNI+D++ RG+SL + D +++ S +Y++ A +NL+
Sbjct: 124 ANDNLDKLNTELKDVTRVMTKNIEDLLYRGDSLEKMADLSSDLRYSSAKYKKAARRVNLE 183
Query: 610 SIYVKY 627
+++ +Y
Sbjct: 184 ALWRQY 189
>sp|Q6C880|SEC22_YARLI Protein transport protein SEC22
Length = 213
Score = 137 bits (346), Expect = 2e-32
Identities = 71/192 (36%), Positives = 121/192 (63%), Gaps = 3/192 (1%)
Frame = +1
Query: 64 RISDGLVLAASMQEDEKIIKSLNHYQCQAKQLLKKFNNLSPSVGSIESDSYMFHYFIDRE 243
R SDGL L+AS+ + ++ +L+ + Q K + +K + S SIES +Y+ HY +
Sbjct: 9 RASDGLPLSASVDDGQE---NLSEQKKQCKLVTQKLSANSADRASIESGNYVIHYLMKDG 65
Query: 244 VCCIILTEKEFSKKMAFAFLTDIMGEFYNEHGS---KIGIVSRPYAFIEFDRYIQKAKKI 414
+ ++E + +K+AF++L ++ EF HG K G+ RPY F+EFD ++QK K++
Sbjct: 66 IVYYCISESSYPRKLAFSYLDELDREFQKSHGQEALKEGV--RPYKFVEFDTFMQKTKRV 123
Query: 415 YTDTRTSRNISQLNYELKDVQRIMVKNIDDVIQRGESLSILDDKLTNISSLSKRYRQDAT 594
Y DTR + N+ +LN EL+DV R+M KNI+D++ RG SL + D +N+ + SK+YR+ A
Sbjct: 124 YQDTRATHNLDKLNTELQDVTRVMTKNIEDLLHRGHSLDHMSDLSSNLRTESKKYRRAAQ 183
Query: 595 YLNLKSIYVKYV 630
+N +++ +Y+
Sbjct: 184 RINWEAMIRQYI 195
>sp|Q94AU2|SC22_ARATH 25.3 kDa vesicle transport protein (AtSEC22)
Length = 218
Score = 136 bits (342), Expect = 6e-32
Identities = 71/190 (37%), Positives = 115/190 (60%), Gaps = 2/190 (1%)
Frame = +1
Query: 64 RISDGLVLAASMQEDEKIIKSLNHYQCQAKQLLKKFNNLSPSVG--SIESDSYMFHYFID 237
R++DGL LA + +D + + + Y+ Q K L K + S+E+ Y+FHY I+
Sbjct: 9 RVTDGLPLAEGL-DDGRDLPDSDMYKQQVKALFKNLSRGQNDASRMSVETGPYVFHYIIE 67
Query: 238 REVCCIILTEKEFSKKMAFAFLTDIMGEFYNEHGSKIGIVSRPYAFIEFDRYIQKAKKIY 417
VC + + ++ + KK+AF +L D+ EF +G I +RPYAFI+FD +IQK KK+Y
Sbjct: 68 GRVCYLTMCDRSYPKKLAFQYLEDLKNEFERVNGPNIETAARPYAFIKFDTFIQKTKKLY 127
Query: 418 TDTRTSRNISQLNYELKDVQRIMVKNIDDVIQRGESLSILDDKLTNISSLSKRYRQDATY 597
DTRT RNI++LN EL +V +IM +N+ +V+ GE L + + + ++S S+ Y A
Sbjct: 128 QDTRTQRNIAKLNDELYEVHQIMTRNVQEVLGVGEKLDQVSEMSSRLTSESRIYADKAKD 187
Query: 598 LNLKSIYVKY 627
LN +++ K+
Sbjct: 188 LNRQALIRKW 197
>sp|Q6CJA0|SEC22_KLULA Protein transport protein SEC22
Length = 214
Score = 127 bits (319), Expect = 3e-29
Identities = 65/186 (34%), Positives = 108/186 (58%), Gaps = 1/186 (0%)
Frame = +1
Query: 73 DGLVLAASMQEDEKIIKSLNHYQCQAKQLLKKFNNLSPSVGSIESDSYMFHYFIDREVCC 252
DGL L AS+ +D SL + + K L+ +F S + ++ES + HY V
Sbjct: 11 DGLPLCASVDDDTD--PSLQEQKKKVKILISRFTPTSANEATVESGDFEIHYIRLNTVVY 68
Query: 253 IILTEKEFSKKMAFAFLTDIMGEFYNEHGSKIGIVS-RPYAFIEFDRYIQKAKKIYTDTR 429
I++ E+ + + +AF++L DI EF + +G ++ + RPY F+ FD ++QK KK+Y D R
Sbjct: 69 IVVAERNYPRNLAFSYLADIQQEFEHSYGGQLSKSNVRPYEFVSFDNFLQKTKKVYNDKR 128
Query: 430 TSRNISQLNYELKDVQRIMVKNIDDVIQRGESLSILDDKLTNISSLSKRYRQDATYLNLK 609
N+ QLN +LK V++IM KNI+D++ RG+SL + D ++ +K+YR A +N
Sbjct: 129 VQGNMDQLNQDLKGVKQIMTKNIEDLLYRGDSLDKMSDMSASLRQDAKKYRASAQKINFD 188
Query: 610 SIYVKY 627
+ +Y
Sbjct: 189 LLISQY 194
>sp|Q74ZD2|SEC22_ASHGO Protein transport protein SEC22
Length = 214
Score = 127 bits (318), Expect = 4e-29
Identities = 67/186 (36%), Positives = 111/186 (59%), Gaps = 1/186 (0%)
Frame = +1
Query: 73 DGLVLAASMQEDEKIIKSLNHYQCQAKQLLKKFNNLSPSVGSIESDSYMFHYFIDREVCC 252
DGL L +S+ +D SL + + K L+ +F S + ++ES +Y HY + V
Sbjct: 11 DGLPLCSSVDDDTD--PSLADQKKKVKVLISRFTPQSANEATLESGAYEMHYVRQQSVVY 68
Query: 253 IILTEKEFSKKMAFAFLTDIMGEFYNEHGSKIGIVS-RPYAFIEFDRYIQKAKKIYTDTR 429
I++ E+ + + +AFA+L ++ EF + +G++ S RPYAF+ FD ++QK KKIY D R
Sbjct: 69 IVIVERGYPRNLAFAYLANVRHEFEHSYGNEYVKPSVRPYAFVSFDNFLQKTKKIYNDKR 128
Query: 430 TSRNISQLNYELKDVQRIMVKNIDDVIQRGESLSILDDKLTNISSLSKRYRQDATYLNLK 609
N+ QLN +L V++IM KNI+D++ RG+SL + D ++ SK+YR+ A +N
Sbjct: 129 VQGNLDQLNSDLLGVKQIMTKNIEDLLYRGDSLDRMSDLSASLRQDSKKYRRSAQKINFD 188
Query: 610 SIYVKY 627
+ +Y
Sbjct: 189 LLLSQY 194
>sp|Q6FWT0|SEC22_CANGA Protein transport protein SEC22
Length = 215
Score = 117 bits (293), Expect = 3e-26
Identities = 61/186 (32%), Positives = 108/186 (58%), Gaps = 1/186 (0%)
Frame = +1
Query: 73 DGLVLAASMQEDEKIIKSLNHYQCQAKQLLKKFNNLSPSVGSIESDSYMFHYFIDREVCC 252
DGL L +S+ +D + SLN + + K ++ + S + ++ES HY + V
Sbjct: 11 DGLPLCSSVDDDISDL-SLNEQKKRIKMVVSRMTPQSANEATLESKDSEIHYIRQQGVIY 69
Query: 253 IILTEKEFSKKMAFAFLTDIMGEFYNEHGSKIGIVS-RPYAFIEFDRYIQKAKKIYTDTR 429
++ E + + +AF++L D+ EF + + +++ + RPYAF FD ++Q+ KK Y+D +
Sbjct: 70 FVICEAGYPRNLAFSYLNDVAVEFQHSYSNELSKPTIRPYAFASFDTFLQRTKKAYSDKK 129
Query: 430 TSRNISQLNYELKDVQRIMVKNIDDVIQRGESLSILDDKLTNISSLSKRYRQDATYLNLK 609
N+ QLN EL V++IM KNI+D++ RG+SL +DD ++ SK+YR+ A +N
Sbjct: 130 VQDNLDQLNQELVGVKQIMSKNIEDLLYRGDSLEKMDDMSNSLKISSKKYRKSAQKINFD 189
Query: 610 SIYVKY 627
+ +Y
Sbjct: 190 LLISQY 195
>sp|P22214|SEC22_YEAST Protein transport protein SEC22 (Protein SLY2)
Length = 214
Score = 109 bits (272), Expect = 8e-24
Identities = 60/186 (32%), Positives = 102/186 (54%), Gaps = 1/186 (0%)
Frame = +1
Query: 73 DGLVLAASMQEDEKIIKSLNHYQCQAKQLLKKFNNLSPSVGSIESDSYMFHYFIDREVCC 252
DGL L S+ + SL + + K ++ + S + ++ES S+ HY V
Sbjct: 11 DGLPLCTSVDNEND--PSLFEQKQKVKIVVSRLTPQSATEATLESGSFEIHYLKKSMVYY 68
Query: 253 IILTEKEFSKKMAFAFLTDIMGEFYNEHGSKIGIVS-RPYAFIEFDRYIQKAKKIYTDTR 429
++ E + + +AF++L DI EF + ++ + RPY F+ FD ++Q KK Y+D +
Sbjct: 69 FVICESGYPRNLAFSYLNDIAQEFEHSFANEYPKPTVRPYQFVNFDNFLQMTKKSYSDKK 128
Query: 430 TSRNISQLNYELKDVQRIMVKNIDDVIQRGESLSILDDKLTNISSLSKRYRQDATYLNLK 609
N+ QLN EL V++IM KNI+D++ RG+SL + D +++ SKRYR+ A +N
Sbjct: 129 VQDNLDQLNQELVGVKQIMSKNIEDLLYRGDSLDKMSDMSSSLKETSKRYRKSAQKINFD 188
Query: 610 SIYVKY 627
+ +Y
Sbjct: 189 LLISQY 194
>sp|Q9SIQ9|V712_ARATH Vesicle-associated membrane protein 712 (AtVAMP712)
Length = 219
Score = 76.3 bits (186), Expect = 7e-14
Identities = 42/152 (27%), Positives = 77/152 (50%)
Frame = +1
Query: 148 AKQLLKKFNNLSPSVGSIESDSYMFHYFIDREVCCIILTEKEFSKKMAFAFLTDIMGEFY 327
AKQ+L+K S S D Y+FH + + + +++ +++ F+FL DI F
Sbjct: 29 AKQILEKIPGNGDSHVSYSQDRYVFHVKRTDGLTVLCMADEDAGRRIPFSFLEDIHQRFV 88
Query: 328 NEHGSKIGIVSRPYAFIEFDRYIQKAKKIYTDTRTSRNISQLNYELKDVQRIMVKNIDDV 507
+G I EF R + + + Y++ + IS++ E+ V+ +M++NID++
Sbjct: 89 RTYGRAIHSAQAYAMNDEFSRVLNQQIEYYSNDPNADTISRIKGEMNQVRDVMIENIDNI 148
Query: 508 IQRGESLSILDDKLTNISSLSKRYRQDATYLN 603
+ RGE L +L DK N+ + R+R+ N
Sbjct: 149 LDRGERLELLVDKTANMQGNTFRFRKQTRRFN 180
>sp|O49377|V711_ARATH Vesicle-associated membrane protein 711 (AtVAMP711) (v-SNARE
synaptobrevin 7C) (AtVAMP7C)
Length = 219
Score = 74.3 bits (181), Expect = 3e-13
Identities = 43/148 (29%), Positives = 75/148 (50%)
Frame = +1
Query: 148 AKQLLKKFNNLSPSVGSIESDSYMFHYFIDREVCCIILTEKEFSKKMAFAFLTDIMGEFY 327
AKQ+L+K + S S D Y+FH + + + E+ +++ FAFL DI F
Sbjct: 29 AKQILEKVPGDNDSNVSYSQDRYVFHVKRTDGLTVLCMAEETAGRRIPFAFLEDIHQRFV 88
Query: 328 NEHGSKIGIVSRPYAFIEFDRYIQKAKKIYTDTRTSRNISQLNYELKDVQRIMVKNIDDV 507
+G + EF R + + Y++ + I+++ E+ V+ +M++NID V
Sbjct: 89 RTYGRAVHTALAYAMNEEFSRVLSQQIDYYSNDPNADRINRIKGEMNQVRGVMIENIDKV 148
Query: 508 IQRGESLSILDDKLTNISSLSKRYRQDA 591
+ RGE L +L DK N+ + R+R+ A
Sbjct: 149 LDRGERLELLVDKTANMQGNTFRFRKQA 176
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,631,022
Number of Sequences: 369166
Number of extensions: 1200804
Number of successful extensions: 3023
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2940
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3006
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 5927776870
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)