Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_F19
(731 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q02874|H2AY_RAT Core histone macro-H2A.1 (Histone macroH... 124 3e-28
sp|Q9P0M6|H2AW_HUMAN Core histone macro-H2A.2 (Histone macr... 122 8e-28
sp|O75367|H2AY_HUMAN Core histone macro-H2A.1 (Histone macr... 120 3e-27
sp|P27325|H2A_URECA Histone H2A 93 6e-19
sp|P69139|H2A3_PSAMI Late histone H2A.3, gonadal >gi|597995... 93 8e-19
sp|P02269|H2A_ASTRU Histone H2A 92 1e-18
sp|P17317|H2AZ_HUMAN Histone H2A.z (H2A/z) 92 1e-18
sp|P04910|H2A2_SCHPO Histone H2A-beta (H2A.2) 92 1e-18
sp|Q9HGX4|H2A_AGABI Histone H2A 92 1e-18
sp|Q8X132|H2A_NEUCR Histone H2A 92 1e-18
>sp|Q02874|H2AY_RAT Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y)
(H2A/y)
Length = 371
Score = 124 bits (311), Expect = 3e-28
Identities = 85/252 (33%), Positives = 125/252 (49%), Gaps = 12/252 (4%)
Frame = +2
Query: 11 KKGFTKSKSQKAGLIFPVSRFHRYLKKQFPSSFRFKISIGAAVYAASVLEYLVAEIAEQA 190
KK S+S KAG+IFPV R RY+KK P +++I +GA VY A+VLEYL AEI E A
Sbjct: 8 KKSTKTSRSAKAGVIFPVGRMLRYIKKGHP---KYRIGVGAPVYMAAVLEYLTAEILELA 64
Query: 191 GNAARILKVKRINPRHIMLAISQDMEMNQALKHVILPSTGRPLNLPGK--PSKQNTKTEL 364
GNAAR K R+ PRHI+LA++ D E+NQ LK V + S G N+ + K+ +K +L
Sbjct: 65 GNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGSKGKL 124
Query: 365 KASI-------IKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQSNSLDV 523
+A I K + ++ V
Sbjct: 125 EAIITPPPAKKAKSPSQKKPVAKKTGGKKGARKSKKQGEVSKAASADSTTEGAPTDGFTV 184
Query: 524 LNERTLFLGQKLVVVQGDIVEMS---ADAVVHPTGGSYGFGGEVGCALSNKGGAELTNEV 694
L+ ++LFLGQKL ++ +I ++ +A+++PT ++G L KGG E V
Sbjct: 185 LSTKSLFLGQKLNLIHSEISNLAGFEVEAIINPTNADIDLKDDLGSTLEKKGGKEFVEAV 244
Query: 695 NKLRATKPSIKV 730
+LR ++V
Sbjct: 245 LELRKKNGPLEV 256
>sp|Q9P0M6|H2AW_HUMAN Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2)
Length = 372
Score = 122 bits (307), Expect = 8e-28
Identities = 88/253 (34%), Positives = 121/253 (47%), Gaps = 13/253 (5%)
Frame = +2
Query: 11 KKGFTKSKSQKAGLIFPVSRFHRYLKKQFPSSFRFKISIGAAVYAASVLEYLVAEIAEQA 190
KK S+S +AG+IFPV R RYLKK +F+++IS+GA VY A+V+EYL AEI E A
Sbjct: 8 KKMSKLSRSARAGVIFPVGRLMRYLKK---GTFKYRISVGAPVYMAAVIEYLAAEILELA 64
Query: 191 GNAARILKVKRINPRHIMLAISQDMEMNQALKHVILPSTG-RPLNLPGKPSKQNTKTELK 367
GNAAR K RI PRHI+LA++ D E+NQ LK V + S G P P +K+
Sbjct: 65 GNAARDNKKARIAPRHILLAVANDEELNQLLKGVTIASGGVLPRIHPELLAKKRGTKGKS 124
Query: 368 ASIIKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQSNS---------LD 520
+I+ SNS
Sbjct: 125 ETILSPPPEKRGRKATSGKKGGKKSKAAKPRTSKKSKPKDSDKEGTSNSTSEDGPGDGFT 184
Query: 521 VLNERTLFLGQKLVVVQGDIV---EMSADAVVHPTGGSYGFGGEVGCALSNKGGAELTNE 691
+L+ ++L LGQKL + Q DI M + +VHPT ++G AL GG E
Sbjct: 185 ILSSKSLVLGQKLSLTQSDISHIGSMRVEGIVHPTTAEIDLKEDIGKALEKAGGKEFLET 244
Query: 692 VNKLRATKPSIKV 730
V +LR ++ ++V
Sbjct: 245 VKELRKSQGPLEV 257
>sp|O75367|H2AY_HUMAN Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y)
(H2A/y)
Length = 372
Score = 120 bits (302), Expect = 3e-27
Identities = 85/253 (33%), Positives = 125/253 (49%), Gaps = 13/253 (5%)
Frame = +2
Query: 11 KKGFTKSKSQKAGLIFPVSRFHRYLKKQFPSSFRFKISIGAAVYAASVLEYLVAEIAEQA 190
KK S+S KAG+IFPV R RY+KK P +++I +GA VY A+VLEYL AEI E A
Sbjct: 8 KKSTKTSRSAKAGVIFPVGRMLRYIKKGHP---KYRIGVGAPVYMAAVLEYLTAEILELA 64
Query: 191 GNAARILKVKRINPRHIMLAISQDMEMNQALKHVILPSTGRPLNLPGK--PSKQNTKTEL 364
GNAAR K R+ PRHI+LA++ D E+NQ LK V + S G N+ + K+ +K +L
Sbjct: 65 GNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGSKGKL 124
Query: 365 KASIIKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQSNSLD-------- 520
+A I S ++ +
Sbjct: 125 EAIITPPPAKKAKSPSQKKPVSKKAGGKKGARKSKKKQGEVSKAASADSTTEGTPADGFT 184
Query: 521 VLNERTLFLGQKLVVVQGDIVEMS---ADAVVHPTGGSYGFGGEVGCALSNKGGAELTNE 691
VL+ ++LFLGQKL ++ +I ++ +A+++PT ++G L KGG E
Sbjct: 185 VLSTKSLFLGQKLNLIHSEISNLAGFEVEAIINPTNADIDPKDDLGNTLEKKGGKEFVEA 244
Query: 692 VNKLRATKPSIKV 730
V +LR ++V
Sbjct: 245 VLELRKKNGPLEV 257
>sp|P27325|H2A_URECA Histone H2A
Length = 125
Score = 93.2 bits (230), Expect = 6e-19
Identities = 56/118 (47%), Positives = 71/118 (60%), Gaps = 4/118 (3%)
Frame = +2
Query: 14 KGFTKSKSQKAGLIFPVSRFHRYLKKQFPSSFRFKISIGAAVYAASVLEYLVAEIAEQAG 193
KG +KS+S +AGL FPV R HR L+K ++ +I GA VY A+V+EYL AE+ E AG
Sbjct: 11 KGKSKSRSSRAGLQFPVGRIHRLLRK---GNYAERIGAGAPVYLAAVMEYLAAEVLELAG 67
Query: 194 NAARILKVKRINPRHIMLAISQDMEMNQALKHVILPSTGRPLNLPG----KPSKQNTK 355
NAAR K RI PRH+ LAI D E+N+ L V + G N+ K S Q TK
Sbjct: 68 NAARDNKKTRIIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLPKKSSQKTK 125
>sp|P69139|H2A3_PSAMI Late histone H2A.3, gonadal
sp|P69140|H2A_PARAN Histone H2A, gonadal
Length = 126
Score = 92.8 bits (229), Expect = 8e-19
Identities = 55/119 (46%), Positives = 73/119 (61%), Gaps = 5/119 (4%)
Frame = +2
Query: 14 KGFTKSKSQKAGLIFPVSRFHRYLKKQFPSSFRFKISIGAAVYAASVLEYLVAEIAEQAG 193
KG KS+S +AGL FPV R HR+L+K ++ ++ GA VY A+VLEYL AEI E AG
Sbjct: 11 KGKAKSRSSRAGLQFPVGRVHRFLRK---GNYANRVGAGAPVYLAAVLEYLAAEILELAG 67
Query: 194 NAARILKVKRINPRHIMLAISQDMEMNQALKHVILPSTG-----RPLNLPGKPSKQNTK 355
NAAR K RI PRH+ LAI D E+N+ L V + G + + LP K +++K
Sbjct: 68 NAARDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTGSKSSK 126
>sp|P02269|H2A_ASTRU Histone H2A
Length = 124
Score = 92.4 bits (228), Expect = 1e-18
Identities = 53/111 (47%), Positives = 70/111 (63%), Gaps = 5/111 (4%)
Frame = +2
Query: 26 KSKSQKAGLIFPVSRFHRYLKKQFPSSFRFKISIGAAVYAASVLEYLVAEIAEQAGNAAR 205
KS+S +AGL FPV R HR+L+K ++ ++ GA VY A+V+EYL AEI E AGNAAR
Sbjct: 14 KSRSSRAGLQFPVGRVHRFLRK---GNYAERVGAGAPVYLAAVMEYLAAEILELAGNAAR 70
Query: 206 ILKVKRINPRHIMLAISQDMEMNQALKHVILPSTG-----RPLNLPGKPSK 343
K RINPRH+ LAI D E+N+ L V + G + + LP K +K
Sbjct: 71 DNKKTRINPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLPKKTAK 121
>sp|P17317|H2AZ_HUMAN Histone H2A.z (H2A/z)
Length = 128
Score = 92.0 bits (227), Expect = 1e-18
Identities = 54/111 (48%), Positives = 71/111 (63%), Gaps = 3/111 (2%)
Frame = +2
Query: 29 SKSQKAGLIFPVSRFHRYLKKQFPSSFRFKISIGAAVYAASVLEYLVAEIAEQAGNAARI 208
S+SQ+AGL FPV R HR+LK + S R + AAVY+A++LEYL AE+ E AGNA++
Sbjct: 19 SRSQRAGLQFPVGRIHRHLKSRTTSHGR--VGATAAVYSAAILEYLTAEVLELAGNASKD 76
Query: 209 LKVKRINPRHIMLAISQDMEMNQALKHVILPSTGRP---LNLPGKPSKQNT 352
LKVKRI PRH+ LAI D E++ +K I P +L GK +Q T
Sbjct: 77 LKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKT 127
>sp|P04910|H2A2_SCHPO Histone H2A-beta (H2A.2)
Length = 131
Score = 92.0 bits (227), Expect = 1e-18
Identities = 55/117 (47%), Positives = 70/117 (59%), Gaps = 10/117 (8%)
Frame = +2
Query: 26 KSKSQKAGLIFPVSRFHRYLKKQFPSSFRFKISIGAAVYAASVLEYLVAEIAEQAGNAAR 205
+S+S KAGL FPV R HR L+K ++ ++ GA VY A+VLEYL AEI E AGNAAR
Sbjct: 17 QSRSAKAGLAFPVGRVHRLLRK---GNYAQRVGAGAPVYLAAVLEYLAAEILELAGNAAR 73
Query: 206 ILKVKRINPRHIMLAISQDMEMNQALKHVILPSTGRPLNL----------PGKPSKQ 346
K RI PRH+ LAI D E+N+ L HV + G N+ GKPS++
Sbjct: 74 DNKKTRIIPRHLQLAIRNDEELNKLLGHVTIAQGGVVPNINAHLLPKQSGKGKPSQE 130
>sp|Q9HGX4|H2A_AGABI Histone H2A
Length = 139
Score = 92.0 bits (227), Expect = 1e-18
Identities = 55/110 (50%), Positives = 69/110 (62%), Gaps = 5/110 (4%)
Frame = +2
Query: 29 SKSQKAGLIFPVSRFHRYLKKQFPSSFRFKISIGAAVYAASVLEYLVAEIAEQAGNAARI 208
S+S KAGL FPV R HR LKK ++ ++ GA VY A+VLEYL AEI E AGNAAR
Sbjct: 22 SRSSKAGLQFPVGRVHRLLKK---GNYAQRVGAGAPVYMAAVLEYLAAEILELAGNAARD 78
Query: 209 LKVKRINPRHIMLAISQDMEMNQALKHVILPSTG-----RPLNLPGKPSK 343
K +RI PRH+ LAI D E+++ L +V++ G P LP K SK
Sbjct: 79 NKKQRIVPRHLQLAIRNDEELHKLLGNVVISQGGVVPHIAPELLPSKSSK 128
>sp|Q8X132|H2A_NEUCR Histone H2A
Length = 134
Score = 92.0 bits (227), Expect = 1e-18
Identities = 59/121 (48%), Positives = 74/121 (61%), Gaps = 8/121 (6%)
Frame = +2
Query: 26 KSKSQKAGLIFPVSRFHRYLKKQFPSSFRFKISIGAAVYAASVLEYLVAEIAEQAGNAAR 205
+S+S KAGL FPV R HR L+K ++ ++ GA VY A+VLEYL AEI E AGNAAR
Sbjct: 18 QSRSSKAGLAFPVGRVHRLLRK---GNYAQRVGAGAPVYLAAVLEYLAAEILELAGNAAR 74
Query: 206 ILKVKRINPRHIMLAISQDMEMNQALKHV------ILPSTGRPLNLPGKPSK--QNTKTE 361
K RI PRH+ LAI D E+N+ L HV +LP+ + L LP K K +N E
Sbjct: 75 DNKKTRIIPRHLQLAIRNDEELNKLLGHVTIAQGGVLPNIHQNL-LPKKTGKTGKNASQE 133
Query: 362 L 364
L
Sbjct: 134 L 134
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,622,319
Number of Sequences: 369166
Number of extensions: 1145703
Number of successful extensions: 3726
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3491
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3630
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6534486000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)