Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_E22
(489 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O61998|HSP90_BRUPA Heat shock protein 90 211 1e-54
sp|P07901|HS90A_MOUSE Heat shock protein HSP 90-alpha (HSP ... 210 1e-54
sp|P07900|HS90A_HUMAN Heat shock protein HSP 90-alpha (HSP 86) 209 2e-54
sp|P46633|HS90A_CRIGR Heat shock protein HSP 90-alpha (HSP 86) 209 4e-54
sp|O02705|HS90A_PIG Heat shock protein HSP 90-alpha (HSP 86) 208 6e-54
sp|P11501|HS90A_CHICK Heat shock protein HSP 90-alpha 207 1e-53
sp|P08238|HS90B_HUMAN Heat shock protein HSP 90-beta (HSP 8... 206 3e-53
sp|Q9GKX8|HS90B_HORSE Heat shock protein HSP 90-beta (HSP 84) 205 4e-53
sp|P11499|HS90B_MOUSE Heat shock protein HSP 90-beta (HSP 8... 205 4e-53
sp|O02192|HSP83_DROAV Heat shock protein 83 (HSP 82) 203 2e-52
>sp|O61998|HSP90_BRUPA Heat shock protein 90
Length = 717
Score = 211 bits (536), Expect = 1e-54
Identities = 109/147 (74%), Positives = 129/147 (87%), Gaps = 5/147 (3%)
Frame = +3
Query: 3 NRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKTLKAR 182
NRLVSSPCCIVTS+YGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHS++K L+ R
Sbjct: 572 NRLVSSPCCIVTSEYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVIKALRER 631
Query: 183 VDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHRMIKLGLGI-EDDDVEMDAT 359
V+ADKNDK+VKDLV+LL+ET+LLSSGF+LEDPQ+H +RI+RMIKLGL I ED++ E A+
Sbjct: 632 VEADKNDKTVKDLVVLLFETALLSSGFSLEDPQLHASRIYRMIKLGLDITEDEEEEAIAS 691
Query: 360 EAGD----VPVVASTAEEDAGKMEEVD 428
+G+ VP + AEEDA +MEEVD
Sbjct: 692 VSGEKDECVPNLVG-AEEDASRMEEVD 717
>sp|P07901|HS90A_MOUSE Heat shock protein HSP 90-alpha (HSP 86) (Tumor specific
transplantation 86 kDa antigen) (TSTA)
Length = 733
Score = 210 bits (535), Expect = 1e-54
Identities = 104/145 (71%), Positives = 125/145 (86%), Gaps = 3/145 (2%)
Frame = +3
Query: 3 NRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKTLKAR 182
NRLV+SPCCIVTS YGW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDHSI++TL+ +
Sbjct: 591 NRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQK 650
Query: 183 VDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHRMIKLGLGIEDDDVEMDATE 362
+ADKNDKSVKDLV+LLYET+LLSSGF+LEDPQ H NRI+RMIKLGLGI++DD +D T
Sbjct: 651 AEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTVDDTS 710
Query: 363 AG---DVPVVASTAEEDAGKMEEVD 428
A ++P + ++D +MEEVD
Sbjct: 711 AAVTEEMPPL--EGDDDTSRMEEVD 733
>sp|P07900|HS90A_HUMAN Heat shock protein HSP 90-alpha (HSP 86)
Length = 732
Score = 209 bits (533), Expect = 2e-54
Identities = 104/145 (71%), Positives = 124/145 (85%), Gaps = 3/145 (2%)
Frame = +3
Query: 3 NRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKTLKAR 182
NRLV+SPCCIVTS YGW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDHSI++TL+ +
Sbjct: 590 NRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQK 649
Query: 183 VDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHRMIKLGLGIEDDDVEMDATE 362
+ADKNDKSVKDLV+LLYET+LLSSGF+LEDPQ H NRI+RMIKLGLGI++DD D T
Sbjct: 650 AEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTS 709
Query: 363 AG---DVPVVASTAEEDAGKMEEVD 428
A ++P + ++D +MEEVD
Sbjct: 710 AAVTEEMPPL--EGDDDTSRMEEVD 732
>sp|P46633|HS90A_CRIGR Heat shock protein HSP 90-alpha (HSP 86)
Length = 733
Score = 209 bits (531), Expect = 4e-54
Identities = 103/145 (71%), Positives = 125/145 (86%), Gaps = 3/145 (2%)
Frame = +3
Query: 3 NRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKTLKAR 182
NRLV+SPCCIVTS YGW+ANMERI+KAQALRD+STMGYMAAKKHLEINPDHSI++TL+ +
Sbjct: 591 NRLVTSPCCIVTSTYGWTANMERIIKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQK 650
Query: 183 VDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHRMIKLGLGIEDDDVEMDATE 362
+ADKNDKSVKDLV+LLYET+LLSSGF+LEDPQ H NRI+RMIKLGLGI++DD +D T
Sbjct: 651 AEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTVDDTS 710
Query: 363 AG---DVPVVASTAEEDAGKMEEVD 428
A ++P + ++D +MEEVD
Sbjct: 711 AAVTEEMPPL--EGDDDTSRMEEVD 733
>sp|O02705|HS90A_PIG Heat shock protein HSP 90-alpha (HSP 86)
Length = 733
Score = 208 bits (529), Expect = 6e-54
Identities = 103/145 (71%), Positives = 124/145 (85%), Gaps = 3/145 (2%)
Frame = +3
Query: 3 NRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKTLKAR 182
NRLV+SPCCIVTS YGW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDHSI++TL+ +
Sbjct: 591 NRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQK 650
Query: 183 VDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHRMIKLGLGIEDDDVEMDATE 362
+ADKNDKSVKDLV+LLYET+LLSSGF+LEDPQ H NRI+RMIKLGLGI++DD D +
Sbjct: 651 AEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDSS 710
Query: 363 AG---DVPVVASTAEEDAGKMEEVD 428
A ++P + ++D +MEEVD
Sbjct: 711 AAVTEEMPPL--EGDDDTSRMEEVD 733
>sp|P11501|HS90A_CHICK Heat shock protein HSP 90-alpha
Length = 728
Score = 207 bits (527), Expect = 1e-53
Identities = 102/143 (71%), Positives = 122/143 (85%), Gaps = 1/143 (0%)
Frame = +3
Query: 3 NRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKTLKAR 182
NRLV+SPCCIVTS YGW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDHSI++TL+ +
Sbjct: 586 NRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQK 645
Query: 183 VDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHRMIKLGLGIEDDDVEM-DAT 359
+ADKNDKSVKDLV+LLYET+LLSSGF+LEDPQ H NRI+RMIKLGLGI++DD +A+
Sbjct: 646 AEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDTAAEEAS 705
Query: 360 EAGDVPVVASTAEEDAGKMEEVD 428
A + ++D +MEEVD
Sbjct: 706 PAVTEEMPPLEGDDDTSRMEEVD 728
>sp|P08238|HS90B_HUMAN Heat shock protein HSP 90-beta (HSP 84) (HSP 90)
Length = 724
Score = 206 bits (523), Expect = 3e-53
Identities = 102/145 (70%), Positives = 124/145 (85%), Gaps = 3/145 (2%)
Frame = +3
Query: 3 NRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKTLKAR 182
NRLVSSPCCIVTS YGW+ANMERIMKAQALRD+STMGYM AKKHLEINPDH I++TL+ +
Sbjct: 582 NRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQK 641
Query: 183 VDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHRMIKLGLGIEDDDV---EMD 353
+ADKNDK+VKDLV+LL+ET+LLSSGF+LEDPQ H NRI+RMIKLGLGI++D+V E +
Sbjct: 642 AEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVAAEEPN 701
Query: 354 ATEAGDVPVVASTAEEDAGKMEEVD 428
A ++P + +EDA +MEEVD
Sbjct: 702 AAVPDEIPPL--EGDEDASRMEEVD 724
>sp|Q9GKX8|HS90B_HORSE Heat shock protein HSP 90-beta (HSP 84)
Length = 724
Score = 205 bits (522), Expect = 4e-53
Identities = 102/145 (70%), Positives = 123/145 (84%), Gaps = 3/145 (2%)
Frame = +3
Query: 3 NRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKTLKAR 182
NRLVSSPCCIVTS YGW+ANMERIMKAQALRD+STMGYM AKKHLEINPDH I++TL+ +
Sbjct: 582 NRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQK 641
Query: 183 VDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHRMIKLGLGIEDDDV---EMD 353
+ADKNDK+VKDLV+LL+ET+LLSSGF+LEDPQ H NRI+RMIKLGLGI++D+V E
Sbjct: 642 AEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVAAEEPS 701
Query: 354 ATEAGDVPVVASTAEEDAGKMEEVD 428
A ++P + +EDA +MEEVD
Sbjct: 702 AAVPDEIPPL--EGDEDASRMEEVD 724
>sp|P11499|HS90B_MOUSE Heat shock protein HSP 90-beta (HSP 84) (Tumor-specific
transplantation 84 kDa antigen) (TSTA)
Length = 724
Score = 205 bits (522), Expect = 4e-53
Identities = 102/145 (70%), Positives = 123/145 (84%), Gaps = 3/145 (2%)
Frame = +3
Query: 3 NRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKTLKAR 182
NRLVSSPCCIVTS YGW+ANMERIMKAQALRD+STMGYM AKKHLEINPDH I++TL+ +
Sbjct: 582 NRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQK 641
Query: 183 VDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHRMIKLGLGIEDDDV---EMD 353
+ADKNDK+VKDLV+LL+ET+LLSSGF+LEDPQ H NRI+RMIKLGLGI++D+V E
Sbjct: 642 AEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVTAEEPS 701
Query: 354 ATEAGDVPVVASTAEEDAGKMEEVD 428
A ++P + +EDA +MEEVD
Sbjct: 702 AAVPDEIPPL--EGDEDASRMEEVD 724
>sp|O02192|HSP83_DROAV Heat shock protein 83 (HSP 82)
Length = 716
Score = 203 bits (517), Expect = 2e-52
Identities = 102/144 (70%), Positives = 120/144 (83%), Gaps = 2/144 (1%)
Frame = +3
Query: 3 NRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKTLKAR 182
NRLV SPCCIVTSQ+GWSANMERIMKAQALRD++TMGYMA KK LEINPDH I++TL+ +
Sbjct: 574 NRLVDSPCCIVTSQFGWSANMERIMKAQALRDTATMGYMAGKKQLEINPDHPIVETLRQK 633
Query: 183 VDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHRMIKLGLGIEDDD--VEMDA 356
DADKNDK+VKDLV+LL+ETSLLSSGF+L+ PQVH +RI+RMIKLGLGI++D+ DA
Sbjct: 634 ADADKNDKAVKDLVILLFETSLLSSGFSLDSPQVHASRIYRMIKLGLGIDEDEPMTTEDA 693
Query: 357 TEAGDVPVVASTAEEDAGKMEEVD 428
AGD P + EDA MEEVD
Sbjct: 694 QSAGDAPSLVEDT-EDASHMEEVD 716
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,434,506
Number of Sequences: 369166
Number of extensions: 821850
Number of successful extensions: 2444
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2334
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2377
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 2970720600
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)