Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_D17
(822 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q90705|EF2_CHICK Elongation factor 2 (EF-2) 415 e-116
sp|P13639|EF2_HUMAN Elongation factor 2 (EF-2) 413 e-115
sp|P58252|EF2_MOUSE Elongation factor 2 (EF-2) 412 e-115
sp|P05086|EF2_MESAU Elongation factor 2 (EF-2) 412 e-115
sp|P05197|EF2_RAT Elongation factor 2 (EF-2) 412 e-115
sp|P09445|EF2_CRIGR Elongation factor 2 (EF-2) 405 e-113
sp|P29691|EF2_CAEEL Elongation factor 2 (EF-2) 401 e-111
sp|P13060|EF2_DROME Elongation factor 2 (EF-2) 395 e-110
sp|Q6BJ25|EF2_DEBHA Elongation factor 2 (EF-2) 351 1e-96
sp|O14460|EF2_SCHPO Elongation factor 2 (EF-2) 348 1e-95
>sp|Q90705|EF2_CHICK Elongation factor 2 (EF-2)
Length = 858
Score = 415 bits (1067), Expect = e-116
Identities = 189/264 (71%), Positives = 220/264 (83%)
Frame = +1
Query: 1 SPNKHNRLYMTATPMSEELSSDIDAGKITARSEIKERGRYLVETYDWDVTESRKIWCFGP 180
SPNKHNRLYM A P + L+ DID G+++AR E+K+R RYL E Y+WDVTE+RKIWCFGP
Sbjct: 595 SPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKQRARYLAEKYEWDVTEARKIWCFGP 654
Query: 181 DGNGPNLVVDVSKGVQYLNEIKDSVVAAFNWATKDGVLCEENMRGVRFNIHDVTLHADAI 360
DG GPN++ D++KGVQYLNEIKDSVVA F WATK+GVLCEENMRGVRF++HDVTLHADAI
Sbjct: 655 DGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGVLCEENMRGVRFDVHDVTLHADAI 714
Query: 361 HRGGGQIIPTARRCFYASVLTASPCLLEPVYQCEIQGPETALGGIYSTLNKRRGIIFSEM 540
HRGGGQIIPTARRC YA VLTA P L+EP+Y EIQ PE +GGIY LN++RG +F E
Sbjct: 715 HRGGGQIIPTARRCLYACVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEES 774
Query: 541 QVAGTPQYVVKAYLPVNESFNFTSELRAQTGGQAFPQCVFDHWQLFPGNPLDPLSKPGIT 720
QVAGTP +VVKAYLPVNESF FT++LR+ TGGQAFPQCVFDHWQ+ PG+P D S+P
Sbjct: 775 QVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDSASRPSQV 834
Query: 721 VKDTRKRKGLSEDVPLLDKFLDKL 792
V +TRKRKGL E +P LD FLDKL
Sbjct: 835 VAETRKRKGLKEGIPALDNFLDKL 858
>sp|P13639|EF2_HUMAN Elongation factor 2 (EF-2)
Length = 858
Score = 413 bits (1061), Expect = e-115
Identities = 188/264 (71%), Positives = 219/264 (82%)
Frame = +1
Query: 1 SPNKHNRLYMTATPMSEELSSDIDAGKITARSEIKERGRYLVETYDWDVTESRKIWCFGP 180
SPNKHNRLYM A P + L+ DID G+++AR E+K+R RYL E Y+WDV E+RKIWCFGP
Sbjct: 595 SPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKQRARYLAEKYEWDVAEARKIWCFGP 654
Query: 181 DGNGPNLVVDVSKGVQYLNEIKDSVVAAFNWATKDGVLCEENMRGVRFNIHDVTLHADAI 360
DG GPN++ D++KGVQYLNEIKDSVVA F WATK+G LCEENMRGVRF++HDVTLHADAI
Sbjct: 655 DGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAI 714
Query: 361 HRGGGQIIPTARRCFYASVLTASPCLLEPVYQCEIQGPETALGGIYSTLNKRRGIIFSEM 540
HRGGGQIIPTARRC YASVLTA P L+EP+Y EIQ PE +GGIY LN++RG +F E
Sbjct: 715 HRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEES 774
Query: 541 QVAGTPQYVVKAYLPVNESFNFTSELRAQTGGQAFPQCVFDHWQLFPGNPLDPLSKPGIT 720
QVAGTP +VVKAYLPVNESF FT++LR+ TGGQAFPQCVFDHWQ+ PG+P D S+P
Sbjct: 775 QVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRPSQV 834
Query: 721 VKDTRKRKGLSEDVPLLDKFLDKL 792
V +TRKRKGL E +P LD FLDKL
Sbjct: 835 VAETRKRKGLKEGIPALDNFLDKL 858
>sp|P58252|EF2_MOUSE Elongation factor 2 (EF-2)
Length = 858
Score = 412 bits (1058), Expect = e-115
Identities = 188/264 (71%), Positives = 218/264 (82%)
Frame = +1
Query: 1 SPNKHNRLYMTATPMSEELSSDIDAGKITARSEIKERGRYLVETYDWDVTESRKIWCFGP 180
SPNKHNRLYM A P + L+ DID G+++AR E+K R RYL E Y+WDV E+RKIWCFGP
Sbjct: 595 SPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKARARYLAEKYEWDVAEARKIWCFGP 654
Query: 181 DGNGPNLVVDVSKGVQYLNEIKDSVVAAFNWATKDGVLCEENMRGVRFNIHDVTLHADAI 360
DG GPN++ D++KGVQYLNEIKDSVVA F WATK+G LCEENMRGVRF++HDVTLHADAI
Sbjct: 655 DGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAI 714
Query: 361 HRGGGQIIPTARRCFYASVLTASPCLLEPVYQCEIQGPETALGGIYSTLNKRRGIIFSEM 540
HRGGGQIIPTARRC YASVLTA P L+EP+Y EIQ PE +GGIY LN++RG +F E
Sbjct: 715 HRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEES 774
Query: 541 QVAGTPQYVVKAYLPVNESFNFTSELRAQTGGQAFPQCVFDHWQLFPGNPLDPLSKPGIT 720
QVAGTP +VVKAYLPVNESF FT++LR+ TGGQAFPQCVFDHWQ+ PG+P D S+P
Sbjct: 775 QVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRPSQV 834
Query: 721 VKDTRKRKGLSEDVPLLDKFLDKL 792
V +TRKRKGL E +P LD FLDKL
Sbjct: 835 VAETRKRKGLKEGIPALDNFLDKL 858
>sp|P05086|EF2_MESAU Elongation factor 2 (EF-2)
Length = 858
Score = 412 bits (1058), Expect = e-115
Identities = 188/264 (71%), Positives = 218/264 (82%)
Frame = +1
Query: 1 SPNKHNRLYMTATPMSEELSSDIDAGKITARSEIKERGRYLVETYDWDVTESRKIWCFGP 180
SPNKHNRLYM A P + L+ DID G+++AR E+K R RYL E Y+WDV E+RKIWCFGP
Sbjct: 595 SPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKARARYLAEKYEWDVAEARKIWCFGP 654
Query: 181 DGNGPNLVVDVSKGVQYLNEIKDSVVAAFNWATKDGVLCEENMRGVRFNIHDVTLHADAI 360
DG GPN++ D++KGVQYLNEIKDSVVA F WATK+G LCEENMRGVRF++HDVTLHADAI
Sbjct: 655 DGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAI 714
Query: 361 HRGGGQIIPTARRCFYASVLTASPCLLEPVYQCEIQGPETALGGIYSTLNKRRGIIFSEM 540
HRGGGQIIPTARRC YASVLTA P L+EP+Y EIQ PE +GGIY LN++RG +F E
Sbjct: 715 HRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEES 774
Query: 541 QVAGTPQYVVKAYLPVNESFNFTSELRAQTGGQAFPQCVFDHWQLFPGNPLDPLSKPGIT 720
QVAGTP +VVKAYLPVNESF FT++LR+ TGGQAFPQCVFDHWQ+ PG+P D S+P
Sbjct: 775 QVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRPSQV 834
Query: 721 VKDTRKRKGLSEDVPLLDKFLDKL 792
V +TRKRKGL E +P LD FLDKL
Sbjct: 835 VAETRKRKGLKEGIPALDNFLDKL 858
>sp|P05197|EF2_RAT Elongation factor 2 (EF-2)
Length = 858
Score = 412 bits (1058), Expect = e-115
Identities = 188/264 (71%), Positives = 218/264 (82%)
Frame = +1
Query: 1 SPNKHNRLYMTATPMSEELSSDIDAGKITARSEIKERGRYLVETYDWDVTESRKIWCFGP 180
SPNKHNRLYM A P + L+ DID G+++AR E+K R RYL E Y+WDV E+RKIWCFGP
Sbjct: 595 SPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKARARYLAEKYEWDVAEARKIWCFGP 654
Query: 181 DGNGPNLVVDVSKGVQYLNEIKDSVVAAFNWATKDGVLCEENMRGVRFNIHDVTLHADAI 360
DG GPN++ D++KGVQYLNEIKDSVVA F WATK+G LCEENMRGVRF++HDVTLHADAI
Sbjct: 655 DGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAI 714
Query: 361 HRGGGQIIPTARRCFYASVLTASPCLLEPVYQCEIQGPETALGGIYSTLNKRRGIIFSEM 540
HRGGGQIIPTARRC YASVLTA P L+EP+Y EIQ PE +GGIY LN++RG +F E
Sbjct: 715 HRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEES 774
Query: 541 QVAGTPQYVVKAYLPVNESFNFTSELRAQTGGQAFPQCVFDHWQLFPGNPLDPLSKPGIT 720
QVAGTP +VVKAYLPVNESF FT++LR+ TGGQAFPQCVFDHWQ+ PG+P D S+P
Sbjct: 775 QVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRPSQV 834
Query: 721 VKDTRKRKGLSEDVPLLDKFLDKL 792
V +TRKRKGL E +P LD FLDKL
Sbjct: 835 VAETRKRKGLKEGIPALDNFLDKL 858
>sp|P09445|EF2_CRIGR Elongation factor 2 (EF-2)
Length = 858
Score = 405 bits (1041), Expect = e-113
Identities = 186/264 (70%), Positives = 216/264 (81%)
Frame = +1
Query: 1 SPNKHNRLYMTATPMSEELSSDIDAGKITARSEIKERGRYLVETYDWDVTESRKIWCFGP 180
SPNKHNRLYM A P + L+ DID G+++AR E+K R RYL E Y+WDV E+RKIWCFGP
Sbjct: 595 SPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKARARYLAEKYEWDVAEARKIWCFGP 654
Query: 181 DGNGPNLVVDVSKGVQYLNEIKDSVVAAFNWATKDGVLCEENMRGVRFNIHDVTLHADAI 360
DG GPN++ D++KGVQYLNEIKDSVVA F WATK+G LCEENMRGVRF++HDVTLHADAI
Sbjct: 655 DGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAI 714
Query: 361 HRGGGQIIPTARRCFYASVLTASPCLLEPVYQCEIQGPETALGGIYSTLNKRRGIIFSEM 540
HR GGQIIPTARRC YASVLTA P L+EP+Y EIQ PE +GGIY LN++RG +F E
Sbjct: 715 HRRGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEES 774
Query: 541 QVAGTPQYVVKAYLPVNESFNFTSELRAQTGGQAFPQCVFDHWQLFPGNPLDPLSKPGIT 720
QVAGTP +VVKAYLPVNESF FT++LR+ TGGQAFPQCVFDHWQ+ PG+P D S+
Sbjct: 775 QVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRGSQV 834
Query: 721 VKDTRKRKGLSEDVPLLDKFLDKL 792
V +TRKRKGL E +P LD FLDKL
Sbjct: 835 VAETRKRKGLKEGIPALDNFLDKL 858
>sp|P29691|EF2_CAEEL Elongation factor 2 (EF-2)
Length = 852
Score = 401 bits (1031), Expect = e-111
Identities = 189/264 (71%), Positives = 218/264 (82%)
Frame = +1
Query: 1 SPNKHNRLYMTATPMSEELSSDIDAGKITARSEIKERGRYLVETYDWDVTESRKIWCFGP 180
SPNKHNRL+ TA PM + L+ DI+ G + AR E K R + L E Y++DVTE+RKIWCFGP
Sbjct: 589 SPNKHNRLHCTAQPMPDGLADDIEGGTVNARDEFKARAKILAEKYEYDVTEARKIWCFGP 648
Query: 181 DGNGPNLVVDVSKGVQYLNEIKDSVVAAFNWATKDGVLCEENMRGVRFNIHDVTLHADAI 360
DG GPNL++DV+KGVQYLNEIKDSVVA F WAT++GVL +ENMRGVRFN+HDVTLHADAI
Sbjct: 649 DGTGPNLLMDVTKGVQYLNEIKDSVVAGFQWATREGVLSDENMRGVRFNVHDVTLHADAI 708
Query: 361 HRGGGQIIPTARRCFYASVLTASPCLLEPVYQCEIQGPETALGGIYSTLNKRRGIIFSEM 540
HRGGGQIIPTARR FYASVLTA P LLEPVY EIQ PE A+GGIY LN+RRG +F E
Sbjct: 709 HRGGGQIIPTARRVFYASVLTAEPRLLEPVYLVEIQCPEAAVGGIYGVLNRRRGHVFEES 768
Query: 541 QVAGTPQYVVKAYLPVNESFNFTSELRAQTGGQAFPQCVFDHWQLFPGNPLDPLSKPGIT 720
QV GTP +VVKAYLPVNESF FT++LR+ TGGQAFPQCVFDHWQ+ PG+PL+ +KP
Sbjct: 769 QVTGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQVLPGDPLEAGTKPNQI 828
Query: 721 VKDTRKRKGLSEDVPLLDKFLDKL 792
V DTRKRKGL E VP LD +LDK+
Sbjct: 829 VLDTRKRKGLKEGVPALDNYLDKM 852
>sp|P13060|EF2_DROME Elongation factor 2 (EF-2)
Length = 844
Score = 395 bits (1015), Expect = e-110
Identities = 183/264 (69%), Positives = 215/264 (81%)
Frame = +1
Query: 1 SPNKHNRLYMTATPMSEELSSDIDAGKITARSEIKERGRYLVETYDWDVTESRKIWCFGP 180
SPNKHNRL M A PM + L DID G ++A+ E K R RYL E YD+DVTE+RKIWCFGP
Sbjct: 581 SPNKHNRLLMKALPMPDGLPEDIDNGDVSAKDEFKARARYLSEKYDYDVTEARKIWCFGP 640
Query: 181 DGNGPNLVVDVSKGVQYLNEIKDSVVAAFNWATKDGVLCEENMRGVRFNIHDVTLHADAI 360
DG GPN ++D +K VQYLNEIKDSVVA F WA+K+G+L +EN+RGVRFNI+DVTLHADAI
Sbjct: 641 DGTGPNFILDCTKSVQYLNEIKDSVVAGFQWASKEGILADENLRGVRFNIYDVTLHADAI 700
Query: 361 HRGGGQIIPTARRCFYASVLTASPCLLEPVYQCEIQGPETALGGIYSTLNKRRGIIFSEM 540
HRGGGQIIPT RRC YA+ +TA P L+EPVY CEIQ PE A+GGIY LN+RRG +F E
Sbjct: 701 HRGGGQIIPTTRRCLYAAAITAKPRLMEPVYLCEIQCPEVAVGGIYGVLNRRRGHVFEEN 760
Query: 541 QVAGTPQYVVKAYLPVNESFNFTSELRAQTGGQAFPQCVFDHWQLFPGNPLDPLSKPGIT 720
QV GTP +VVKAYLPVNESF FT++LR+ TGGQAFPQCVFDHWQ+ PG+P +P SKP
Sbjct: 761 QVVGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQVLPGDPSEPSSKPYAI 820
Query: 721 VKDTRKRKGLSEDVPLLDKFLDKL 792
V+DTRKRKGL E +P L ++LDKL
Sbjct: 821 VQDTRKRKGLKEGLPDLSQYLDKL 844
>sp|Q6BJ25|EF2_DEBHA Elongation factor 2 (EF-2)
Length = 842
Score = 351 bits (901), Expect = 1e-96
Identities = 169/264 (64%), Positives = 200/264 (75%)
Frame = +1
Query: 1 SPNKHNRLYMTATPMSEELSSDIDAGKITARSEIKERGRYLVETYDWDVTESRKIWCFGP 180
SPNKHNR+Y+ A P+ EE+S DI+ G I R + K R R L + + WDVT++RKIWCFGP
Sbjct: 579 SPNKHNRIYVKAQPIDEEVSLDIEKGVINPRDDFKARARILADNHGWDVTDARKIWCFGP 638
Query: 181 DGNGPNLVVDVSKGVQYLNEIKDSVVAAFNWATKDGVLCEENMRGVRFNIHDVTLHADAI 360
DGNGPNLVVD +K VQYLNEIKDSVVAAF WATK+G + EN+R VR NI DVTLHADAI
Sbjct: 639 DGNGPNLVVDQTKAVQYLNEIKDSVVAAFQWATKEGPIFGENVRSVRVNILDVTLHADAI 698
Query: 361 HRGGGQIIPTARRCFYASVLTASPCLLEPVYQCEIQGPETALGGIYSTLNKRRGIIFSEM 540
HRGGGQIIPT RR YAS+L A P + EPV+ EIQ PE A+GGIYS LNK+RG + SE
Sbjct: 699 HRGGGQIIPTMRRVTYASMLLAEPAIQEPVFLVEIQCPENAIGGIYSVLNKKRGQVISEE 758
Query: 541 QVAGTPQYVVKAYLPVNESFNFTSELRAQTGGQAFPQCVFDHWQLFPGNPLDPLSKPGIT 720
Q GTP + VKAYLPVNESF F+ ELR TGGQAFPQ +FDHW G+P DP SK G
Sbjct: 759 QRPGTPLFTVKAYLPVNESFGFSGELRQSTGGQAFPQLIFDHWANLNGDPTDPTSKVGTI 818
Query: 721 VKDTRKRKGLSEDVPLLDKFLDKL 792
VK+ R+R+G+ DVP +++ DKL
Sbjct: 819 VKEKRERQGMKPDVPGYEEYYDKL 842
>sp|O14460|EF2_SCHPO Elongation factor 2 (EF-2)
Length = 842
Score = 348 bits (893), Expect = 1e-95
Identities = 170/264 (64%), Positives = 198/264 (75%)
Frame = +1
Query: 1 SPNKHNRLYMTATPMSEELSSDIDAGKITARSEIKERGRYLVETYDWDVTESRKIWCFGP 180
SPNKHNR++MTA PMSEELS I+ G + R + K R R + + + WDVT++RKIWCFGP
Sbjct: 579 SPNKHNRIFMTAEPMSEELSVAIETGHVNPRDDFKVRARIMADEFGWDVTDARKIWCFGP 638
Query: 181 DGNGPNLVVDVSKGVQYLNEIKDSVVAAFNWATKDGVLCEENMRGVRFNIHDVTLHADAI 360
D G N+VVD +K V YLNEIKDSVVAAF WA+K+G + EEN+R RFNI DV LHADAI
Sbjct: 639 DTTGANVVVDQTKAVAYLNEIKDSVVAAFAWASKEGPMFEENLRSCRFNILDVVLHADAI 698
Query: 361 HRGGGQIIPTARRCFYASVLTASPCLLEPVYQCEIQGPETALGGIYSTLNKRRGIIFSEM 540
HRGGGQIIPTARR YAS L ASP + EPV+ EIQ E A+GGIYS LNK+RG +FSE
Sbjct: 699 HRGGGQIIPTARRVVYASTLLASPIIQEPVFLVEIQVSENAMGGIYSVLNKKRGHVFSEE 758
Query: 541 QVAGTPQYVVKAYLPVNESFNFTSELRAQTGGQAFPQCVFDHWQLFPGNPLDPLSKPGIT 720
Q GTP Y +KAYLPVNESF FT ELR T GQAFPQ VFDHW G+PLDP SKPG
Sbjct: 759 QRVGTPLYNIKAYLPVNESFGFTGELRQATAGQAFPQLVFDHWSPMSGDPLDPTSKPGQI 818
Query: 721 VKDTRKRKGLSEDVPLLDKFLDKL 792
V + RKRKGL E+VP ++ D+L
Sbjct: 819 VCEARKRKGLKENVPDYTEYYDRL 842
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 99,880,248
Number of Sequences: 369166
Number of extensions: 2117171
Number of successful extensions: 5523
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5179
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5363
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7907893860
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)