Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_D14
(564 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P61291|PSME3_PIG Proteasome activator complex subunit 3 ... 147 1e-35
sp|Q06323|PSME1_HUMAN Proteasome activator complex subunit ... 109 4e-24
sp|P58238|PSME1_MACFA Proteasome activator complex subunit ... 109 4e-24
sp|Q4U5R3|PSME1_BOVIN Proteasome activator complex subunit ... 107 3e-23
sp|Q64L94|PSE1_PIG Proteasome activator complex subunit 1 (... 106 3e-23
sp|P97371|PSME1_MOUSE Proteasome activator complex subunit ... 105 6e-23
sp|Q63797|PSME1_RAT Proteasome activator complex subunit 1 ... 105 6e-23
sp|Q63798|PSME2_RAT Proteasome activator complex subunit 2 ... 99 7e-21
sp|P97372|PSME2_MOUSE Proteasome activator complex subunit ... 97 4e-20
sp|Q9UL46|PSE2_HUMAN Proteasome activator complex subunit 2... 96 5e-20
>sp|P61291|PSME3_PIG Proteasome activator complex subunit 3 (Proteasome activator
28-gamma subunit) (PA28gamma) (PA28g) (Activator of
multicatalytic protease subunit 3)
sp|P61290|PSME3_MOUSE Proteasome activator complex subunit 3 (Proteasome activator
28-gamma subunit) (PA28gamma) (PA28g) (Activator of
multicatalytic protease subunit 3) (11S regulator
complex gamma subunit) (REG-gamma) (Ki nuclear
autoantigen)
sp|P61289|PSME3_HUMAN Proteasome activator complex subunit 3 (Proteasome activator
28-gamma subunit) (PA28gamma) (PA28g) (Activator of
multicatalytic protease subunit 3) (11S regulator
complex gamma subunit) (REG-gamma) (Ki nuclear
autoantigen)
Length = 254
Score = 147 bits (372), Expect = 1e-35
Identities = 66/133 (49%), Positives = 100/133 (75%)
Frame = +2
Query: 8 LRPHITRLMEEALQVRLWIQFNIPKIEDGNNFGVGIQEEVLGEAVSIEKDASNFLEQMSR 187
++P I L+E+ V++W+Q IP+IEDGNNFGV IQEE + E ++E +A+++L+Q+SR
Sbjct: 122 VKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQISR 181
Query: 188 YHISRAKMLTKVIKFPNIMDYHECVKNADEMQAISLRYIVMEMRNHYAILHDMINKNLER 367
Y+I+RAK+++K+ K+P++ DY V DE + ISLR I+ E+RN Y LHDMI KN+E+
Sbjct: 182 YYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIEK 241
Query: 368 IKIPRSNNTISMY 406
IK PRS+N ++Y
Sbjct: 242 IKRPRSSNAETLY 254
>sp|Q06323|PSME1_HUMAN Proteasome activator complex subunit 1 (Proteasome activator
28-alpha subunit) (PA28alpha) (PA28a) (Activator of
multicatalytic protease subunit 1) (11S regulator
complex alpha subunit) (REG-alpha) (Interferon gamma
up-regulated I-5111 protein) (IGUP I-5111)
Length = 249
Score = 109 bits (273), Expect = 4e-24
Identities = 54/133 (40%), Positives = 79/133 (59%)
Frame = +2
Query: 8 LRPHITRLMEEALQVRLWIQFNIPKIEDGNNFGVGIQEEVLGEAVSIEKDASNFLEQMSR 187
L+P I ++E+ V W+Q IP+IEDGNNFGV +QE+V S+ F Q+S+
Sbjct: 117 LKPEIKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQISK 176
Query: 188 YHISRAKMLTKVIKFPNIMDYHECVKNADEMQAISLRYIVMEMRNHYAILHDMINKNLER 367
Y R +TK K P++ DY + V DE + +R +VME+RN YA+L+D+I KN E+
Sbjct: 177 YFSERGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYAVLYDIILKNFEK 236
Query: 368 IKIPRSNNTISMY 406
+K PR +Y
Sbjct: 237 LKKPRGETKGMIY 249
>sp|P58238|PSME1_MACFA Proteasome activator complex subunit 1 (Proteasome activator
28-alpha subunit) (PA28alpha) (PA28a) (Activator of
multicatalytic protease subunit 1) (11S regulator
complex alpha subunit) (REG-alpha)
Length = 249
Score = 109 bits (273), Expect = 4e-24
Identities = 54/133 (40%), Positives = 79/133 (59%)
Frame = +2
Query: 8 LRPHITRLMEEALQVRLWIQFNIPKIEDGNNFGVGIQEEVLGEAVSIEKDASNFLEQMSR 187
L+P I ++E+ V W+Q IP+IEDGNNFGV +QE+V S+ F Q+S+
Sbjct: 117 LKPEIKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQISK 176
Query: 188 YHISRAKMLTKVIKFPNIMDYHECVKNADEMQAISLRYIVMEMRNHYAILHDMINKNLER 367
Y R +TK K P++ DY + V DE + +R +VME+RN YA+L+D+I KN E+
Sbjct: 177 YFSERGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYAVLYDIILKNFEK 236
Query: 368 IKIPRSNNTISMY 406
+K PR +Y
Sbjct: 237 LKKPRGETKGMIY 249
>sp|Q4U5R3|PSME1_BOVIN Proteasome activator complex subunit 1 (Proteasome activator
28-alpha subunit) (PA28alpha) (PA28a)
Length = 249
Score = 107 bits (266), Expect = 3e-23
Identities = 52/133 (39%), Positives = 79/133 (59%)
Frame = +2
Query: 8 LRPHITRLMEEALQVRLWIQFNIPKIEDGNNFGVGIQEEVLGEAVSIEKDASNFLEQMSR 187
++P I ++E+ V W+Q IP+IEDGNNFGV +QE+V ++ F Q+S+
Sbjct: 117 VKPEIKDVIEKLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTALHTKLEGFHTQISK 176
Query: 188 YHISRAKMLTKVIKFPNIMDYHECVKNADEMQAISLRYIVMEMRNHYAILHDMINKNLER 367
Y R +TK K P++ DY + V DE + +R +VME+RN YA+L+D+I KN E+
Sbjct: 177 YFSERGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYAVLYDIILKNFEK 236
Query: 368 IKIPRSNNTISMY 406
+K PR +Y
Sbjct: 237 LKKPRGETKGMIY 249
>sp|Q64L94|PSE1_PIG Proteasome activator complex subunit 1 (Proteasome activator
28-alpha subunit) (PA28alpha) (PA28a)
Length = 249
Score = 106 bits (265), Expect = 3e-23
Identities = 52/133 (39%), Positives = 78/133 (58%)
Frame = +2
Query: 8 LRPHITRLMEEALQVRLWIQFNIPKIEDGNNFGVGIQEEVLGEAVSIEKDASNFLEQMSR 187
L+P I ++E+ V W+Q IP+IEDGNNFGV +QE+V ++ F Q+S+
Sbjct: 117 LKPEIKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTALHTKLEGFHTQISK 176
Query: 188 YHISRAKMLTKVIKFPNIMDYHECVKNADEMQAISLRYIVMEMRNHYAILHDMINKNLER 367
Y R + K K P++ DY + V DE + +R +VME+RN YA+L+D+I KN E+
Sbjct: 177 YFSERGDAVAKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYAVLYDIILKNFEK 236
Query: 368 IKIPRSNNTISMY 406
+K PR +Y
Sbjct: 237 LKKPRGETKGMIY 249
>sp|P97371|PSME1_MOUSE Proteasome activator complex subunit 1 (Proteasome activator
28-alpha subunit) (PA28alpha) (PA28a) (Activator of
multicatalytic protease subunit 1) (11S regulator
complex alpha subunit) (REG-alpha)
Length = 249
Score = 105 bits (263), Expect = 6e-23
Identities = 52/133 (39%), Positives = 77/133 (57%)
Frame = +2
Query: 8 LRPHITRLMEEALQVRLWIQFNIPKIEDGNNFGVGIQEEVLGEAVSIEKDASNFLEQMSR 187
L+P I + E+ V W+Q IP+IEDGNNFGV +QE+V ++ F Q+S+
Sbjct: 117 LKPEIKDVTEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTNLHTKLEGFHTQISK 176
Query: 188 YHISRAKMLTKVIKFPNIMDYHECVKNADEMQAISLRYIVMEMRNHYAILHDMINKNLER 367
Y R + K K P++ DY + V DE + +R +VME+RN YA+L+D+I KN E+
Sbjct: 177 YFSERGDAVAKAAKQPHVGDYRQLVHELDEAEYQEIRLMVMEIRNAYAVLYDIILKNFEK 236
Query: 368 IKIPRSNNTISMY 406
+K PR +Y
Sbjct: 237 LKKPRGETKGMIY 249
>sp|Q63797|PSME1_RAT Proteasome activator complex subunit 1 (Proteasome activator
28-alpha subunit) (PA28alpha) (PA28a) (Activator of
multicatalytic protease subunit 1) (11S regulator
complex alpha subunit) (REG-alpha)
Length = 249
Score = 105 bits (263), Expect = 6e-23
Identities = 52/133 (39%), Positives = 77/133 (57%)
Frame = +2
Query: 8 LRPHITRLMEEALQVRLWIQFNIPKIEDGNNFGVGIQEEVLGEAVSIEKDASNFLEQMSR 187
L+P I ++E+ V W+Q IP+IEDGNNFGV +Q +V S+ F Q+S+
Sbjct: 117 LKPEIKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQAKVFELMTSLHTKLEGFQTQISK 176
Query: 188 YHISRAKMLTKVIKFPNIMDYHECVKNADEMQAISLRYIVMEMRNHYAILHDMINKNLER 367
Y R + K K P++ DY + V DE + +R +VME+RN YA+L+D+I KN E+
Sbjct: 177 YFSERGDAVAKAAKQPHVGDYRQLVHELDEAEYQEIRLMVMEIRNAYAVLYDIILKNFEK 236
Query: 368 IKIPRSNNTISMY 406
+K PR +Y
Sbjct: 237 LKKPRGETKGMIY 249
>sp|Q63798|PSME2_RAT Proteasome activator complex subunit 2 (Proteasome activator
28-beta subunit) (PA28beta) (PA28b) (Activator of
multicatalytic protease subunit 2) (11S regulator
complex beta subunit) (REG-beta)
Length = 238
Score = 99.0 bits (245), Expect = 7e-21
Identities = 52/134 (38%), Positives = 77/134 (57%)
Frame = +2
Query: 5 ILRPHITRLMEEALQVRLWIQFNIPKIEDGNNFGVGIQEEVLGEAVSIEKDASNFLEQMS 184
+++P + L E+ + V WIQ IPKIEDGN+FGV IQE+VL +++ F +S
Sbjct: 105 LVKPEVWTLKEKCILVITWIQHLIPKIEDGNDFGVAIQEKVLERVNAVKTKVEAFQTAIS 164
Query: 185 RYHISRAKMLTKVIKFPNIMDYHECVKNADEMQAISLRYIVMEMRNHYAILHDMINKNLE 364
+Y R + K K ++MDY V DE +LR +V+++R YA LH +I+ NLE
Sbjct: 165 KYFSERGDAVAKASKDTHVMDYRALVHERDEAAYGALRAMVLDLRAFYAELHHIISSNLE 224
Query: 365 RIKIPRSNNTISMY 406
+I P+ SMY
Sbjct: 225 KIVNPKGEEKPSMY 238
>sp|P97372|PSME2_MOUSE Proteasome activator complex subunit 2 (Proteasome activator
28-beta subunit) (PA28beta) (PA28b) (Activator of
multicatalytic protease subunit 2) (11S regulator
complex beta subunit) (REG-beta)
Length = 239
Score = 96.7 bits (239), Expect = 4e-20
Identities = 51/134 (38%), Positives = 77/134 (57%)
Frame = +2
Query: 5 ILRPHITRLMEEALQVRLWIQFNIPKIEDGNNFGVGIQEEVLGEAVSIEKDASNFLEQMS 184
+++P + L E+ + V WIQ IPKIEDGN+FGV IQE+VL +++ F +S
Sbjct: 106 LVKPEVWTLKEKCILVITWIQHLIPKIEDGNDFGVAIQEKVLERVNAVKTKVEAFQTTIS 165
Query: 185 RYHISRAKMLTKVIKFPNIMDYHECVKNADEMQAISLRYIVMEMRNHYAILHDMINKNLE 364
+Y R + K K ++MDY V DE +LR +V+++R YA L+ +I+ NLE
Sbjct: 166 KYFSERGDAVAKASKDTHVMDYRALVHERDEAAYGALRAMVLDLRAFYAELYHIISSNLE 225
Query: 365 RIKIPRSNNTISMY 406
+I P+ SMY
Sbjct: 226 KIVNPKGEEKPSMY 239
>sp|Q9UL46|PSE2_HUMAN Proteasome activator complex subunit 2 (Proteasome activator
28-beta subunit) (PA28beta) (PA28b) (Activator of
multicatalytic protease subunit 2) (11S regulator
complex beta subunit) (REG-beta)
Length = 239
Score = 96.3 bits (238), Expect = 5e-20
Identities = 51/134 (38%), Positives = 76/134 (56%)
Frame = +2
Query: 5 ILRPHITRLMEEALQVRLWIQFNIPKIEDGNNFGVGIQEEVLGEAVSIEKDASNFLEQMS 184
+++P + L E+ + V WIQ IPKIEDGN+FGV IQE+VL +++ F +S
Sbjct: 106 LVKPEVWTLKEKCILVITWIQHLIPKIEDGNDFGVAIQEKVLERVNAVKTKVEAFQTTIS 165
Query: 185 RYHISRAKMLTKVIKFPNIMDYHECVKNADEMQAISLRYIVMEMRNHYAILHDMINKNLE 364
+Y R + K K ++MDY V DE LR +V+++R YA L+ +I+ NLE
Sbjct: 166 KYFSERGDAVAKASKETHVMDYRALVHERDEAAYGELRAMVLDLRAFYAELYHIISSNLE 225
Query: 365 RIKIPRSNNTISMY 406
+I P+ SMY
Sbjct: 226 KIVNPKGEEKPSMY 239
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,455,327
Number of Sequences: 369166
Number of extensions: 997826
Number of successful extensions: 2326
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2267
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2326
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 4078830820
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)