Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_C01
(542 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O60830|TI17B_HUMAN Mitochondrial import inner membrane t... 130 2e-30
sp|Q99595|TI17A_HUMAN Mitochondrial import inner membrane t... 129 4e-30
sp|Q9Z0V8|TI17A_MOUSE Mitochondrial import inner membrane t... 128 1e-29
sp|Q9VNA0|TI17A_DROME Probable mitochondrial import inner m... 128 1e-29
sp|Q9Z0V7|TI17B_MOUSE Mitochondrial import inner membrane t... 127 2e-29
sp|O35092|TI17A_RAT Mitochondrial import inner membrane tra... 127 2e-29
sp|Q9VGA2|TI17C_DROME Probable mitochondrial import inner m... 122 6e-28
sp|P39515|TIM17_YEAST Mitochondrial import inner membrane t... 118 8e-27
sp|P59670|TIM17_NEUCR Mitochondrial import inner membrane t... 118 1e-26
sp|O44477|TIM17_CAEEL Probable mitochondrial import inner m... 117 2e-26
>sp|O60830|TI17B_HUMAN Mitochondrial import inner membrane translocase subunit Tim17 B
(JM3)
Length = 172
Score = 130 bits (328), Expect = 2e-30
Identities = 65/139 (46%), Positives = 87/139 (62%), Gaps = 1/139 (0%)
Frame = -2
Query: 523 MDAY-RDPCPWRIFSDXXXXXXXXXXXXGLFNFVAGFKDAPSGLSKRLISAATRCKIRSP 347
M+ Y R+PCPWRI D G+F + GF++AP G+ RL +A +IR+P
Sbjct: 1 MEEYAREPCPWRIVDDCGGAFTMGVIGGGVFQAIKGFRNAPVGIRHRLRGSANAVRIRAP 60
Query: 346 VLGGSFAMWGGTFSCVDCALIYGRKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGA 167
+GGSFA+WGG FS +DC L+ R KEDP NSI +G +TG VLA R G + G A +G
Sbjct: 61 QIGGSFAVWGGLFSTIDCGLVRLRGKEDPWNSITSGALTGAVLAARSGPLAMVGSAMMGG 120
Query: 166 VLLGIIEGCGILFQRFSTQ 110
+LL +IEG GIL R++ Q
Sbjct: 121 ILLALIEGVGILLTRYTAQ 139
>sp|Q99595|TI17A_HUMAN Mitochondrial import inner membrane translocase subunit Tim17 A
(Inner membrane preprotein translocase Tim17a)
Length = 171
Score = 129 bits (325), Expect = 4e-30
Identities = 63/138 (45%), Positives = 88/138 (63%), Gaps = 1/138 (0%)
Frame = -2
Query: 523 MDAY-RDPCPWRIFSDXXXXXXXXXXXXGLFNFVAGFKDAPSGLSKRLISAATRCKIRSP 347
M+ Y R+PCPWRI D G+F + GF+++P G++ RL + T K R+P
Sbjct: 1 MEEYAREPCPWRIVDDCGGAFTMGTIGGGIFQAIKGFRNSPVGVNHRLRGSLTAIKTRAP 60
Query: 346 VLGGSFAMWGGTFSCVDCALIYGRKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGA 167
LGGSFA+WGG FS +DC+++ R KEDP NSI +G +TG +LA R G + G A +G
Sbjct: 61 QLGGSFAVWGGLFSMIDCSMVQVRGKEDPWNSITSGALTGAILAARNGPVAMVGSAAMGG 120
Query: 166 VLLGIIEGCGILFQRFST 113
+LL +IEG GIL RF++
Sbjct: 121 ILLALIEGAGILLTRFAS 138
>sp|Q9Z0V8|TI17A_MOUSE Mitochondrial import inner membrane translocase subunit Tim17 A
(Inner membrane preprotein translocase Tim17a)
Length = 171
Score = 128 bits (321), Expect = 1e-29
Identities = 63/138 (45%), Positives = 87/138 (63%), Gaps = 1/138 (0%)
Frame = -2
Query: 523 MDAY-RDPCPWRIFSDXXXXXXXXXXXXGLFNFVAGFKDAPSGLSKRLISAATRCKIRSP 347
M+ Y R+PCPWRI D G+F GF+++P G++ RL + T K R+P
Sbjct: 1 MEEYAREPCPWRIVDDCGGAFTMGTIGGGIFQAFKGFRNSPVGINHRLRGSLTAIKTRAP 60
Query: 346 VLGGSFAMWGGTFSCVDCALIYGRKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGA 167
LGGSFA+WGG FS +DC+++ R KEDP NSI +G +TG +LA R G + G A +G
Sbjct: 61 QLGGSFAVWGGLFSTIDCSMVQIRGKEDPWNSITSGALTGAILAARNGPVAMVGSAAMGG 120
Query: 166 VLLGIIEGCGILFQRFST 113
+LL +IEG GIL RF++
Sbjct: 121 ILLALIEGAGILLTRFAS 138
>sp|Q9VNA0|TI17A_DROME Probable mitochondrial import inner membrane translocase subunit
Tim17 1
Length = 179
Score = 128 bits (321), Expect = 1e-29
Identities = 64/156 (41%), Positives = 90/156 (57%)
Frame = -2
Query: 511 RDPCPWRIFSDXXXXXXXXXXXXGLFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLGGS 332
R+PCP+RI D G F + GF++APSGL RL + RS ++GG+
Sbjct: 6 REPCPFRIVEDCGGAFAMGALGGGAFQAIKGFRNAPSGLGYRLSGGLAAVRARSGLVGGN 65
Query: 331 FAMWGGTFSCVDCALIYGRKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGAVLLGI 152
FA+WG TFS +DC+L+Y RKKEDP N+I++G TGG+LA R G + + A VG LL +
Sbjct: 66 FAVWGATFSAIDCSLVYFRKKEDPWNAIISGATTGGILAARTGLTSMLSSALVGGALLAL 125
Query: 151 IEGCGILFQRFSTQAIVEESMPDNNQTISHQSLGLQ 44
IEG GI+ +S + + S + Q + L Q
Sbjct: 126 IEGVGIVVSHYSADSYRQVSPVERQQRYKQELLRQQ 161
>sp|Q9Z0V7|TI17B_MOUSE Mitochondrial import inner membrane translocase subunit Tim17 B
Length = 172
Score = 127 bits (319), Expect = 2e-29
Identities = 63/139 (45%), Positives = 85/139 (61%), Gaps = 1/139 (0%)
Frame = -2
Query: 523 MDAY-RDPCPWRIFSDXXXXXXXXXXXXGLFNFVAGFKDAPSGLSKRLISAATRCKIRSP 347
M+ Y R+PCPWRI D G+F + GF++AP G+ R + +IR+P
Sbjct: 1 MEEYAREPCPWRIVDDCGGAFTMGVIGGGVFQAIKGFRNAPVGIRHRFRGSVNAVRIRAP 60
Query: 346 VLGGSFAMWGGTFSCVDCALIYGRKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGA 167
+GGSFA+WGG FS +DC L+ R KEDP NSI +G +TG VLA R G + G A +G
Sbjct: 61 QIGGSFAVWGGLFSTIDCGLVRLRGKEDPWNSISSGALTGAVLAARSGPLAMVGSAMMGG 120
Query: 166 VLLGIIEGCGILFQRFSTQ 110
+LL +IEG GIL R++ Q
Sbjct: 121 ILLALIEGVGILLTRYTAQ 139
>sp|O35092|TI17A_RAT Mitochondrial import inner membrane translocase subunit Tim17 A
(Inner membrane preprotein translocase Tim17a)
Length = 171
Score = 127 bits (319), Expect = 2e-29
Identities = 63/138 (45%), Positives = 86/138 (62%), Gaps = 1/138 (0%)
Frame = -2
Query: 523 MDAY-RDPCPWRIFSDXXXXXXXXXXXXGLFNFVAGFKDAPSGLSKRLISAATRCKIRSP 347
M+ Y R+PCPWRI D G+F GF+++P G++ RL + T K R+P
Sbjct: 1 MEEYAREPCPWRIVDDCGGAFTMGTIGGGIFQAFKGFRNSPVGVNHRLRGSLTAIKTRAP 60
Query: 346 VLGGSFAMWGGTFSCVDCALIYGRKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGA 167
LGGSFA+WGG FS +DC ++ R KEDP NSI +G +TG +LA R G + G A +G
Sbjct: 61 QLGGSFAVWGGLFSTIDCGMVQIRGKEDPWNSITSGALTGAILAARNGPVAMVGSAAMGG 120
Query: 166 VLLGIIEGCGILFQRFST 113
+LL +IEG GIL RF++
Sbjct: 121 ILLALIEGAGILLTRFAS 138
>sp|Q9VGA2|TI17C_DROME Probable mitochondrial import inner membrane translocase subunit
Tim17 3
Length = 222
Score = 122 bits (306), Expect = 6e-28
Identities = 60/129 (46%), Positives = 80/129 (62%)
Frame = -2
Query: 523 MDAYRDPCPWRIFSDXXXXXXXXXXXXGLFNFVAGFKDAPSGLSKRLISAATRCKIRSPV 344
M+ R PCP RI D LF F+ GF++AP+GL +RL K+R+P
Sbjct: 1 MEYNRQPCPIRIVEDCGCAFMMGTIGGSLFEFLKGFRNAPTGLQRRLYGGIDLVKMRTPS 60
Query: 343 LGGSFAMWGGTFSCVDCALIYGRKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGAV 164
+ GSFA+WG TFS VDCAL++ R++ED NSIL+G TGG+LA R G +A A VG +
Sbjct: 61 IAGSFAVWGATFSTVDCALVHYRQREDAWNSILSGAATGGILAARNGIRAMANSALVGCL 120
Query: 163 LLGIIEGCG 137
+L +IEG G
Sbjct: 121 VLAMIEGAG 129
>sp|P39515|TIM17_YEAST Mitochondrial import inner membrane translocase subunit TIM17
(Mitochondrial protein import protein 2) (Mitochondrial
inner membrane protein MIM17)
Length = 158
Score = 118 bits (296), Expect = 8e-27
Identities = 59/135 (43%), Positives = 83/135 (61%)
Frame = -2
Query: 520 DAYRDPCPWRIFSDXXXXXXXXXXXXGLFNFVAGFKDAPSGLSKRLISAATRCKIRSPVL 341
D RDPCP I +D +++ + GF+++P G +R A + K R+PVL
Sbjct: 4 DHSRDPCPIVILNDFGGAFAMGAIGGVVWHGIKGFRNSPLG--ERGSGAMSAIKARAPVL 61
Query: 340 GGSFAMWGGTFSCVDCALIYGRKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGAVL 161
GG+F +WGG FS DCA+ RK+EDP N+I+AG TGG LA+RGGW + A L
Sbjct: 62 GGNFGVWGGLFSTFDCAVKAVRKREDPWNAIIAGFFTGGALAVRGGWRHTRNSSITCACL 121
Query: 160 LGIIEGCGILFQRFS 116
LG+IEG G++FQR++
Sbjct: 122 LGVIEGVGLMFQRYA 136
>sp|P59670|TIM17_NEUCR Mitochondrial import inner membrane translocase subunit tim-17
Length = 155
Score = 118 bits (295), Expect = 1e-26
Identities = 68/155 (43%), Positives = 90/155 (58%), Gaps = 3/155 (1%)
Frame = -2
Query: 523 MDAYRDPCPWRIFSDXXXXXXXXXXXXGLFNFVAGFKDAPSGLSKRLISAATRCKIRSPV 344
MD RDPCPW I +D +++ + GF+++P G +R I A T K+R+P
Sbjct: 1 MDHTRDPCPWVILNDFGGAFAMGAIGGTIWHGIKGFRNSPYG--ERRIGAITAIKMRAPA 58
Query: 343 LGGSFAMWGGTFSCVDCALIYGRK-KEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGA 167
LGG+F +WGG FS DCA+ R KEDP NSILAG TGG LA+RGG+ A A
Sbjct: 59 LGGNFGVWGGLFSTFDCAIKGLRNHKEDPWNSILAGFFTGGALAVRGGYKAARNGAIGCA 118
Query: 166 VLLGIIEGCGILFQRFSTQAIVEE--SMPDNNQTI 68
VLL +IEG GI FQ+ A E + P +N+ +
Sbjct: 119 VLLAVIEGVGIGFQKMLAGATKLEAPAPPPSNEKV 153
>sp|O44477|TIM17_CAEEL Probable mitochondrial import inner membrane translocase subunit
Tim17
Length = 181
Score = 117 bits (292), Expect = 2e-26
Identities = 64/159 (40%), Positives = 94/159 (59%), Gaps = 1/159 (0%)
Frame = -2
Query: 523 MDAY-RDPCPWRIFSDXXXXXXXXXXXXGLFNFVAGFKDAPSGLSKRLISAATRCKIRSP 347
M+ Y R+PCP+RI D +F G+K+A G K+L+ ++RS
Sbjct: 1 MEEYTREPCPYRIGDDIGSAFAMGLVGGSIFQAFGGYKNAAKG--KKLVGMMREVRMRST 58
Query: 346 VLGGSFAMWGGTFSCVDCALIYGRKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGA 167
+ G FA WGG FS +DC L+ RKKEDPINSI++GG+TG +LAIR G +AG A +G+
Sbjct: 59 LTGVQFAAWGGMFSTIDCCLVAIRKKEDPINSIVSGGLTGALLAIRSGPKVMAGSAILGS 118
Query: 166 VLLGIIEGCGILFQRFSTQAIVEESMPDNNQTISHQSLG 50
V+L +IEG G++ R+ A+++ + P +SLG
Sbjct: 119 VILAMIEGVGLVTTRW-MGAMMDPTQPPPEALDDPRSLG 156
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,993,194
Number of Sequences: 369166
Number of extensions: 1281600
Number of successful extensions: 3951
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3673
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3912
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 3734833040
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)