Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_A15
(503 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q6P542|ABCF1_MOUSE ATP-binding cassette sub-family F mem... 196 2e-50
sp|Q6MG08|ABCF1_RAT ATP-binding cassette sub-family F membe... 195 6e-50
sp|Q8NE71|ABCF1_HUMAN ATP-binding cassette sub-family F mem... 192 4e-49
sp|Q7YR37|ABCF1_PANTR ATP-binding cassette sub-family F mem... 192 4e-49
sp|Q767L0|ABCF1_PIG ATP-binding cassette sub-family F member 1 192 4e-49
sp|P40024|YEM6_YEAST Probable ATP-dependent transporter YER... 128 7e-30
sp|Q9UG63|ABCF2_HUMAN ATP-binding cassette sub-family F mem... 118 9e-27
sp|Q99LE6|ABCF2_MOUSE ATP-binding cassette sub-family F mem... 118 9e-27
sp|P43535|GCN20_YEAST Protein GCN20 100 3e-21
sp|P63390|YHES_ECO57 Hypothetical ABC transporter ATP-bindi... 83 3e-16
>sp|Q6P542|ABCF1_MOUSE ATP-binding cassette sub-family F member 1
Length = 837
Score = 196 bits (499), Expect = 2e-50
Identities = 99/166 (59%), Positives = 123/166 (74%)
Frame = +1
Query: 1 DEDIGPTELLEKPKEYQVKFDFPNPQKLSGSILSLTNVSFAYSKTSTDLFTKVDFGVDMN 180
+E P ELL++PKEY V+F FP+P LS +L L V+F Y + LF +DFG+DM+
Sbjct: 585 EESQEPPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGY-EGQKPLFKNLDFGIDMD 643
Query: 181 SRVSIVGPNGVGKSTFLKLLTGEIEPTIGERSLNHRIKLGKYNQHSGDQLNMKETPVEYL 360
SR+ IVGPNGVGKST L LLTG++ PT GE NHR+K+G +NQ +QL+M+ETP EYL
Sbjct: 644 SRICIVGPNGVGKSTLLLLLTGKLTPTNGEMRKNHRLKIGFFNQQYAEQLHMEETPTEYL 703
Query: 361 RRLFNLGYQDARQNLGRFGLESHAHEIPNSSLSGGQRARVAFAQLA 498
+R FNL YQDAR+ LGRFGLESHAH I LSGGQ+ARV FA+LA
Sbjct: 704 QRSFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELA 749
Score = 40.0 bits (92), Expect = 0.003
Identities = 39/156 (25%), Positives = 58/156 (37%), Gaps = 31/156 (19%)
Frame = +1
Query: 118 FAYSKTSTDLFTKVDFGVDMNSRVSIVGPNGVGKSTFLKLLTG---EIEPTIGE------ 270
F+ S +LF D + R +VGPNG GK+T LK + I P I
Sbjct: 301 FSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQE 360
Query: 271 -------------RSLNHRIKLGKYNQHSGDQLNM-KETPVEYLRRLFN--------LGY 384
R+ R++L + + QL +T E L +++
Sbjct: 361 VVADETPAVQAVLRADTKRLRLLEEERRLQGQLEQGDDTAAEKLEKVYEELRATGAAAAE 420
Query: 385 QDARQNLGRFGLESHAHEIPNSSLSGGQRARVAFAQ 492
AR+ L G + P SGG R RV+ A+
Sbjct: 421 AKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLAR 456
>sp|Q6MG08|ABCF1_RAT ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50)
Length = 839
Score = 195 bits (495), Expect = 6e-50
Identities = 98/166 (59%), Positives = 123/166 (74%)
Frame = +1
Query: 1 DEDIGPTELLEKPKEYQVKFDFPNPQKLSGSILSLTNVSFAYSKTSTDLFTKVDFGVDMN 180
+E P ELL++P+EY V+F FP+P LS +L L V+F Y + LF +DFG+DM+
Sbjct: 587 EESQDPPELLKRpreYTVRFTFPDPPPLSPPVLGLHGVTFGY-EGQKPLFKNLDFGIDMD 645
Query: 181 SRVSIVGPNGVGKSTFLKLLTGEIEPTIGERSLNHRIKLGKYNQHSGDQLNMKETPVEYL 360
SR+ IVGPNGVGKST L LLTG++ PT GE NHR+K+G +NQ +QL+M+ETP EYL
Sbjct: 646 SRICIVGPNGVGKSTLLLLLTGKLTPTNGEMRKNHRLKIGFFNQQYAEQLHMEETPTEYL 705
Query: 361 RRLFNLGYQDARQNLGRFGLESHAHEIPNSSLSGGQRARVAFAQLA 498
+R FNL YQDAR+ LGRFGLESHAH I LSGGQ+ARV FA+LA
Sbjct: 706 QRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELA 751
Score = 40.0 bits (92), Expect = 0.003
Identities = 39/156 (25%), Positives = 58/156 (37%), Gaps = 31/156 (19%)
Frame = +1
Query: 118 FAYSKTSTDLFTKVDFGVDMNSRVSIVGPNGVGKSTFLKLLTG---EIEPTIGE------ 270
F+ S +LF D + R +VGPNG GK+T LK + I P I
Sbjct: 303 FSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQE 362
Query: 271 -------------RSLNHRIKLGKYNQHSGDQLNM-KETPVEYLRRLFN--------LGY 384
R+ R++L + + QL +T E L +++
Sbjct: 363 VVADETPAVQAVLRADTKRLRLLEEEKRLQGQLEQGDDTAAEKLEKVYEELRATGAAAAE 422
Query: 385 QDARQNLGRFGLESHAHEIPNSSLSGGQRARVAFAQ 492
AR+ L G + P SGG R RV+ A+
Sbjct: 423 AKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLAR 458
>sp|Q8NE71|ABCF1_HUMAN ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50)
(TNF-alpha-stimulated ABC protein)
Length = 845
Score = 192 bits (488), Expect = 4e-49
Identities = 97/159 (61%), Positives = 119/159 (74%)
Frame = +1
Query: 22 ELLEKPKEYQVKFDFPNPQKLSGSILSLTNVSFAYSKTSTDLFTKVDFGVDMNSRVSIVG 201
ELL++PKEY V+F FP+P LS +L L V+F Y + LF +DFG+DM+SR+ IVG
Sbjct: 600 ELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGY-QGQKPLFKNLDFGIDMDSRICIVG 658
Query: 202 PNGVGKSTFLKLLTGEIEPTIGERSLNHRIKLGKYNQHSGDQLNMKETPVEYLRRLFNLG 381
PNGVGKST L LLTG++ PT GE NHR+K+G +NQ +QL M+ETP EYL+R FNL
Sbjct: 659 PNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRGFNLP 718
Query: 382 YQDARQNLGRFGLESHAHEIPNSSLSGGQRARVAFAQLA 498
YQDAR+ LGRFGLESHAH I LSGGQ+ARV FA+LA
Sbjct: 719 YQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELA 757
Score = 41.2 bits (95), Expect = 0.001
Identities = 40/156 (25%), Positives = 58/156 (37%), Gaps = 31/156 (19%)
Frame = +1
Query: 118 FAYSKTSTDLFTKVDFGVDMNSRVSIVGPNGVGKSTFLKLLTG---EIEPTIGE------ 270
F+ S +LF D + R +VGPNG GK+T LK + I P I
Sbjct: 309 FSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQE 368
Query: 271 -------------RSLNHRIKLGKYNQHSGDQLNM-KETPVEYLRRLFN--------LGY 384
R+ R+KL + + QL +T E L +++
Sbjct: 369 VVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKVYEELRATGAAAAE 428
Query: 385 QDARQNLGRFGLESHAHEIPNSSLSGGQRARVAFAQ 492
AR+ L G + P SGG R RV+ A+
Sbjct: 429 AKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLAR 464
>sp|Q7YR37|ABCF1_PANTR ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50)
Length = 807
Score = 192 bits (488), Expect = 4e-49
Identities = 97/159 (61%), Positives = 119/159 (74%)
Frame = +1
Query: 22 ELLEKPKEYQVKFDFPNPQKLSGSILSLTNVSFAYSKTSTDLFTKVDFGVDMNSRVSIVG 201
ELL++PKEY V+F FP+P LS +L L V+F Y + LF +DFG+DM+SR+ IVG
Sbjct: 562 ELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGY-EGQKPLFKNLDFGIDMDSRICIVG 620
Query: 202 PNGVGKSTFLKLLTGEIEPTIGERSLNHRIKLGKYNQHSGDQLNMKETPVEYLRRLFNLG 381
PNGVGKST L LLTG++ PT GE NHR+K+G +NQ +QL M+ETP EYL+R FNL
Sbjct: 621 PNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRGFNLP 680
Query: 382 YQDARQNLGRFGLESHAHEIPNSSLSGGQRARVAFAQLA 498
YQDAR+ LGRFGLESHAH I LSGGQ+ARV FA+LA
Sbjct: 681 YQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELA 719
Score = 41.6 bits (96), Expect = 0.001
Identities = 40/156 (25%), Positives = 59/156 (37%), Gaps = 31/156 (19%)
Frame = +1
Query: 118 FAYSKTSTDLFTKVDFGVDMNSRVSIVGPNGVGKSTFLKLLTG---EIEPTIGE------ 270
F+ S +LF D + + R +VGPNG GK+T LK + I P I
Sbjct: 271 FSISAHGKELFVNADLYIVASRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQE 330
Query: 271 -------------RSLNHRIKLGKYNQHSGDQLNM-KETPVEYLRRLFN--------LGY 384
R+ R+KL + + QL +T E L +++
Sbjct: 331 VVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKVYEELRATGAAAAE 390
Query: 385 QDARQNLGRFGLESHAHEIPNSSLSGGQRARVAFAQ 492
AR+ L G + P SGG R RV+ A+
Sbjct: 391 AKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLAR 426
>sp|Q767L0|ABCF1_PIG ATP-binding cassette sub-family F member 1
Length = 807
Score = 192 bits (488), Expect = 4e-49
Identities = 97/159 (61%), Positives = 119/159 (74%)
Frame = +1
Query: 22 ELLEKPKEYQVKFDFPNPQKLSGSILSLTNVSFAYSKTSTDLFTKVDFGVDMNSRVSIVG 201
ELL++PKEY V+F FP+P LS +L L V+F Y + LF +DFG+DM+SR+ IVG
Sbjct: 562 ELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGY-EGQKPLFKNLDFGIDMDSRICIVG 620
Query: 202 PNGVGKSTFLKLLTGEIEPTIGERSLNHRIKLGKYNQHSGDQLNMKETPVEYLRRLFNLG 381
PNGVGKST L LLTG++ PT GE NHR+K+G +NQ +QL M+ETP EYL+R FNL
Sbjct: 621 PNGVGKSTLLLLLTGKLTPTRGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRGFNLP 680
Query: 382 YQDARQNLGRFGLESHAHEIPNSSLSGGQRARVAFAQLA 498
YQDAR+ LGRFGLESHAH I LSGGQ+ARV FA+LA
Sbjct: 681 YQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELA 719
Score = 40.0 bits (92), Expect = 0.003
Identities = 39/156 (25%), Positives = 58/156 (37%), Gaps = 31/156 (19%)
Frame = +1
Query: 118 FAYSKTSTDLFTKVDFGVDMNSRVSIVGPNGVGKSTFLKLLTG---EIEPTIGE------ 270
F+ S +LF D + R +VGPNG GK+T LK + I P I
Sbjct: 271 FSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQE 330
Query: 271 -------------RSLNHRIKLGKYNQHSGDQLNM-KETPVEYLRRLFN--------LGY 384
R+ R+KL + + QL +T + L +++
Sbjct: 331 VVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAADRLEKVYEELRATGAAAAE 390
Query: 385 QDARQNLGRFGLESHAHEIPNSSLSGGQRARVAFAQ 492
AR+ L G + P SGG R RV+ A+
Sbjct: 391 AKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLAR 426
>sp|P40024|YEM6_YEAST Probable ATP-dependent transporter YER036C
Length = 610
Score = 128 bits (322), Expect = 7e-30
Identities = 68/152 (44%), Positives = 102/152 (67%), Gaps = 4/152 (2%)
Frame = +1
Query: 58 FDFPNPQKLSGSILSLTNVSFAY-SKTSTDLFTKVDFGVDMNSRVSIVGPNGVGKSTFLK 234
F FP ++L +L+ ++SF Y S S +L+ ++FGVDM+SR+++VGPNGVGKST LK
Sbjct: 380 FRFPQVERLPPPVLAFDDISFHYESNPSENLYEHLNFGVDMDSRIALVGPNGVGKSTLLK 439
Query: 235 LLTGEIEPTIGERSLNHRIKLGKYNQHSGDQLNMKETPVEYLRRLFNLGYQDA---RQNL 405
++TGE+ P G S + +KLG Y+QHS DQL++ ++ +E++R ++ QD R L
Sbjct: 440 IMTGELTPQSGRVSRHTHVKLGVYSQHSQDQLDLTKSALEFVRDKYSNISQDFQFWRGQL 499
Query: 406 GRFGLESHAHEIPNSSLSGGQRARVAFAQLAL 501
GR+GL + ++LS GQR+RV FA LAL
Sbjct: 500 GRYGLTGEGQTVQMATLSEGQRSRVVFALLAL 531
Score = 30.8 bits (68), Expect = 1.9
Identities = 15/29 (51%), Positives = 20/29 (68%), Gaps = 2/29 (6%)
Frame = +1
Query: 160 DFGVDMN--SRVSIVGPNGVGKSTFLKLL 240
D G+++N R ++G NG GKSTFLK L
Sbjct: 99 DSGLELNYGRRYGLLGENGCGKSTFLKAL 127
>sp|Q9UG63|ABCF2_HUMAN ATP-binding cassette sub-family F member 2 (Iron-inhibited ABC
transporter 2)
Length = 623
Score = 118 bits (295), Expect = 9e-27
Identities = 59/151 (39%), Positives = 96/151 (63%), Gaps = 2/151 (1%)
Frame = +1
Query: 52 VKFDFPNPQKLSGSILSLTNVSFAYSKTSTDLFTKVDFGVDMNSRVSIVGPNGVGKSTFL 231
+ F FP K+ ++ + NVSF Y+K ++ ++FG+D+++RV++VGPNG GKST L
Sbjct: 381 LSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGIDLDTRVALVGPNGAGKSTLL 440
Query: 232 KLLTGEIEPTIGERSLNHRIKLGKYNQHSGDQLNMKETPVEYLRRLFN--LGYQDARQNL 405
KLLTGE+ PT G + +K+G+Y+QH +QL++ +P+EY+ + + ++ R+ +
Sbjct: 441 KLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPLEYMMKCYPEIKEKEEMRKII 500
Query: 406 GRFGLESHAHEIPNSSLSGGQRARVAFAQLA 498
GR+GL P +LS GQ+ RV A LA
Sbjct: 501 GRYGLTGKQQVSPIRNLSDGQKCRVCLAWLA 531
>sp|Q99LE6|ABCF2_MOUSE ATP-binding cassette sub-family F member 2
Length = 628
Score = 118 bits (295), Expect = 9e-27
Identities = 59/151 (39%), Positives = 96/151 (63%), Gaps = 2/151 (1%)
Frame = +1
Query: 52 VKFDFPNPQKLSGSILSLTNVSFAYSKTSTDLFTKVDFGVDMNSRVSIVGPNGVGKSTFL 231
+ F FP K+ ++ + NVSF Y+K ++ ++FG+D+++RV++VGPNG GKST L
Sbjct: 386 LSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGIDLDTRVALVGPNGAGKSTLL 445
Query: 232 KLLTGEIEPTIGERSLNHRIKLGKYNQHSGDQLNMKETPVEYLRRLFN--LGYQDARQNL 405
KLLTGE+ PT G + +K+G+Y+QH +QL++ +P+EY+ + + ++ R+ +
Sbjct: 446 KLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPLEYMMKCYPEIKEKEEMRKII 505
Query: 406 GRFGLESHAHEIPNSSLSGGQRARVAFAQLA 498
GR+GL P +LS GQ+ RV A LA
Sbjct: 506 GRYGLTGKQQVSPIRNLSDGQKCRVCLAWLA 536
>sp|P43535|GCN20_YEAST Protein GCN20
Length = 752
Score = 100 bits (248), Expect = 3e-21
Identities = 58/161 (36%), Positives = 96/161 (59%), Gaps = 2/161 (1%)
Frame = +1
Query: 25 LLEKPKEYQ-VKFDFPNPQKLSGSILSLTNVSFAYSKTSTDLFTKVDFGVDMNSRVSIVG 201
+LE P++ + + F FP KLS I+ L +VSF Y + + L V+ V M+SR+++VG
Sbjct: 507 VLEPPEQDKTIDFKFPECDKLSPPIIQLQDVSFGYDENNL-LLKDVNLDVQMDSRIALVG 565
Query: 202 PNGVGKSTFLKLLTGEIEPTIGERSLNHRIKLGKYNQHSGDQLNMKETPVEYLRRLF-NL 378
NG GK+T LK++ ++ P G S N R+++G + QH D +++ + V+++ + F
Sbjct: 566 ANGCGKTTLLKIMMEQLRPLKGFVSRNPRLRIGYFTQHHVDSMDLTTSAVDWMSKSFPGK 625
Query: 379 GYQDARQNLGRFGLESHAHEIPNSSLSGGQRARVAFAQLAL 501
++ R++LG FG+ LSGGQ++RVAFA L L
Sbjct: 626 TDEEYRRHLGSFGITGTLGLQKMQLLSGGQKSRVAFAALCL 666
Score = 28.5 bits (62), Expect = 9.5
Identities = 18/75 (24%), Positives = 31/75 (41%), Gaps = 4/75 (5%)
Frame = +1
Query: 31 EKPKEYQVKFDFPNPQKLSGSILSLTNVSF----AYSKTSTDLFTKVDFGVDMNSRVSIV 198
+K ++Y F NP + S ++ Y + + + R +V
Sbjct: 172 QKEEDYDSFFLQINPLEFGSSAGKSKDIHIDTFDLYVGDGQRILSNAQLTLSFGHRYGLV 231
Query: 199 GPNGVGKSTFLKLLT 243
G NG+GKST L+ L+
Sbjct: 232 GQNGIGKSTLLRALS 246
>sp|P63390|YHES_ECO57 Hypothetical ABC transporter ATP-binding protein yheS
sp|P63389|YHES_ECOLI Hypothetical ABC transporter ATP-binding protein yheS
Length = 637
Score = 83.2 bits (204), Expect = 3e-16
Identities = 50/146 (34%), Positives = 72/146 (49%), Gaps = 1/146 (0%)
Frame = +1
Query: 55 KFDFPNPQKLSGSILSLTNVSFAYSKTSTDLFTKVDFGVDMNSRVSIVGPNGVGKSTFLK 234
+F F P+ L +L + VS Y + + + SR+ ++G NG GKST +K
Sbjct: 299 RFSFRAPESLPNPLLKMEKVSAGYGDRI--ILDSIKLNLVPGSRIGLLGRNGAGKSTLIK 356
Query: 235 LLTGEIEPTIGERSLNHRIKLGKYNQHSGDQLNMKETPVEYLRRLFNLGY-QDARQNLGR 411
LL GE+ P GE L IKLG + QH + L E+P+++L RL Q R LG
Sbjct: 357 LLAGELAPVSGEIGLAKGIKLGYFAQHQLEYLRADESPIQHLARLAPQELEQKLRDYLGG 416
Query: 412 FGLESHAHEIPNSSLSGGQRARVAFA 489
FG + SGG++AR+ A
Sbjct: 417 FGFQGDKVTEETRRFSGGEKARLVLA 442
Score = 32.7 bits (73), Expect = 0.50
Identities = 18/50 (36%), Positives = 25/50 (50%)
Frame = +1
Query: 169 VDMNSRVSIVGPNGVGKSTFLKLLTGEIEPTIGERSLNHRIKLGKYNQHS 318
++ +V +VG NG GKST L LL EI G + +L NQ +
Sbjct: 24 INPGQKVGLVGKNGCGKSTLLALLKNEISADGGSYTFPGSWQLAWVNQET 73
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.315 0.135 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,025,174
Number of Sequences: 369166
Number of extensions: 1183067
Number of successful extensions: 6225
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5370
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6017
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 3218280650
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)