Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_A11
(546 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q13637|RAB32_HUMAN Ras-related protein Rab-32 246 3e-65
sp|Q9CZE3|RAB32_MOUSE Ras-related protein Rab-32 244 8e-65
sp|Q8QZZ8|RAB38_MOUSE Ras-related protein Rab-38 242 5e-64
sp|P57729|RAB38_HUMAN Ras-related protein Rab-38 (Antigen N... 240 1e-63
sp|Q91YQ1|RAB7L_MOUSE Ras-related protein Rab-7L1 (Rab-7-li... 196 3e-50
sp|O14966|RAB7L_HUMAN Ras-related protein Rab-7L1 (Rab-7-li... 195 7e-50
sp|O94655|YPT7_SCHPO Ras-related protein ypt7 131 1e-30
sp|Q9C2L8|RAB7_NEUCR Probable Ras-related protein Rab7 124 2e-28
sp|P32939|YPT7_YEAST GTP-binding protein YPT7 120 2e-27
sp|P36411|RAB7_DICDI Ras-related protein Rab7 120 3e-27
>sp|Q13637|RAB32_HUMAN Ras-related protein Rab-32
Length = 225
Score = 246 bits (628), Expect = 3e-65
Identities = 120/173 (69%), Positives = 143/173 (82%)
Frame = +3
Query: 27 KEYLFKVRVIGELGAGKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRLQLWD 206
+E+LFKV VIGELG GKTSIIKRYVH+ FSQHYRATIGVDFALKVL WD ++VRLQLWD
Sbjct: 22 REHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWD 81
Query: 207 IAGQERFGNMLRVYYKDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIPCILL 386
IAGQERFGNM RVYYK+A+GAF+V+D++R+STFEAV+KWK DLDSKV PNG PIP +LL
Sbjct: 82 IAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAVLL 141
Query: 387 GNKSDCEREGRLSDTNYLDQFVNEHGFVKRFDTSAKENIGIDEAANALVDKML 545
NK D ++ S + +DQF EHGF F+TSAK+NI I+EAA LV+K+L
Sbjct: 142 ANKCDQNKDSSQSPSQ-VDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKIL 193
>sp|Q9CZE3|RAB32_MOUSE Ras-related protein Rab-32
Length = 223
Score = 244 bits (624), Expect = 8e-65
Identities = 118/173 (68%), Positives = 142/173 (82%)
Frame = +3
Query: 27 KEYLFKVRVIGELGAGKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRLQLWD 206
+E+LFKV VIGELG GKTSIIKRYVH+ FSQHYRATIGVDFALKVL WD ++VRLQLWD
Sbjct: 20 REHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWD 79
Query: 207 IAGQERFGNMLRVYYKDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIPCILL 386
IAGQERFGNM RVYYK+A+GAF+V+D++R+STF+AV+KWK DLDSKV PNG PIP +LL
Sbjct: 80 IAGQERFGNMTRVYYKEALGAFVVFDISRSSTFDAVLKWKNDLDSKVHLPNGSPIPAVLL 139
Query: 387 GNKSDCEREGRLSDTNYLDQFVNEHGFVKRFDTSAKENIGIDEAANALVDKML 545
NK D +++ S + +DQF +HGF F+TSAK+NI IDEA LV+ ML
Sbjct: 140 ANKCDQKKDNSQSPSQ-MDQFCKDHGFTGWFETSAKDNINIDEATRFLVENML 191
>sp|Q8QZZ8|RAB38_MOUSE Ras-related protein Rab-38
Length = 211
Score = 242 bits (617), Expect = 5e-64
Identities = 119/177 (67%), Positives = 141/177 (79%)
Frame = +3
Query: 15 QMTEKEYLFKVRVIGELGAGKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRL 194
Q KE+L+K+ VIG+LG GKTSIIKRYVH+ FS HYRATIGVDFALKVL WD +VVRL
Sbjct: 2 QTPHKEHLYKLLVIGDLGVGKTSIIKRYVHQNFSSHYRATIGVDFALKVLHWDPETVVRL 61
Query: 195 QLWDIAGQERFGNMLRVYYKDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIP 374
QLWDIAGQERFGNM RVYY++AMGAFIV+DVTR +TFEAV KWK DLDSK+T PNG P+
Sbjct: 62 QLWDIAGQERFGNMTRVYYREAMGAFIVFDVTRPATFEAVAKWKNDLDSKLTLPNGKPVS 121
Query: 375 CILLGNKSDCEREGRLSDTNYLDQFVNEHGFVKRFDTSAKENIGIDEAANALVDKML 545
+LL NK D ++ +++ +DQF EHGFV F+TSAKENI IDEA+ LV +L
Sbjct: 122 VVLLANKCDQGKDVLMNNGLKMDQFCKEHGFVGWFETSAKENINIDEASRCLVKHIL 178
>sp|P57729|RAB38_HUMAN Ras-related protein Rab-38 (Antigen NY-MEL-1)
Length = 211
Score = 240 bits (613), Expect = 1e-63
Identities = 118/177 (66%), Positives = 141/177 (79%)
Frame = +3
Query: 15 QMTEKEYLFKVRVIGELGAGKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRL 194
Q KE+L+K+ VIG+LG GKTSIIKRYVH+ FS HYRATIGVDFALKVL WD +VVRL
Sbjct: 2 QAPHKEHLYKLLVIGDLGVGKTSIIKRYVHQNFSSHYRATIGVDFALKVLHWDPETVVRL 61
Query: 195 QLWDIAGQERFGNMLRVYYKDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIP 374
QLWDIAGQERFGNM RVYY++AMGAFIV+DVTR +TFEAV KWK DLDSK++ PNG P+
Sbjct: 62 QLWDIAGQERFGNMTRVYYREAMGAFIVFDVTRPATFEAVAKWKNDLDSKLSLPNGKPVS 121
Query: 375 CILLGNKSDCEREGRLSDTNYLDQFVNEHGFVKRFDTSAKENIGIDEAANALVDKML 545
+LL NK D ++ +++ +DQF EHGFV F+TSAKENI IDEA+ LV +L
Sbjct: 122 VVLLANKCDQGKDVLMNNGLKMDQFCKEHGFVGWFETSAKENINIDEASRCLVKHIL 178
>sp|Q91YQ1|RAB7L_MOUSE Ras-related protein Rab-7L1 (Rab-7-like protein 1)
Length = 204
Score = 196 bits (498), Expect = 3e-50
Identities = 94/176 (53%), Positives = 127/176 (72%)
Frame = +3
Query: 18 MTEKEYLFKVRVIGELGAGKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRLQ 197
M +++LFKV V+G+ GKTS+++RY FS+HY++T+GVDFALKVL W DS +VRLQ
Sbjct: 1 MGSRDHLFKVLVVGDAAVGKTSLVQRYSQDSFSKHYKSTVGVDFALKVLQWSDSEMVRLQ 60
Query: 198 LWDIAGQERFGNMLRVYYKDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIPC 377
LWDIAGQERF +M R+YY+DA I++DVT A+TF +WK+DLDSK+T P+G+P+PC
Sbjct: 61 LWDIAGQERFTSMTRLYYRDASACVIMFDVTNATTFSNSQRWKQDLDSKLTLPSGEPVPC 120
Query: 378 ILLGNKSDCEREGRLSDTNYLDQFVNEHGFVKRFDTSAKENIGIDEAANALVDKML 545
+LL NKSD D +D+F E+GF +TS KEN I+EA LV+KM+
Sbjct: 121 LLLANKSDLSPWAVSRD--QIDRFSKENGFTGWTETSVKENKNINEAMRVLVEKMM 174
>sp|O14966|RAB7L_HUMAN Ras-related protein Rab-7L1 (Rab-7-like protein 1)
Length = 203
Score = 195 bits (495), Expect = 7e-50
Identities = 91/176 (51%), Positives = 126/176 (71%)
Frame = +3
Query: 18 MTEKEYLFKVRVIGELGAGKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRLQ 197
M +++LFKV V+G+ GKTS+++RY FS+HY++T+GVDFALKVL W D +VRLQ
Sbjct: 1 MGSRDHLFKVLVVGDAAVGKTSLVQRYSQDSFSKHYKSTVGVDFALKVLQWSDYEIVRLQ 60
Query: 198 LWDIAGQERFGNMLRVYYKDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIPC 377
LWDIAGQERF +M R+YY+DA I++DVT A+TF +WK+DLDSK+T PNG+P+PC
Sbjct: 61 LWDIAGQERFTSMTRLYYRDASACVIMFDVTNATTFSNSQRWKQDLDSKLTLPNGEPVPC 120
Query: 378 ILLGNKSDCEREGRLSDTNYLDQFVNEHGFVKRFDTSAKENIGIDEAANALVDKML 545
+LL NK C+ + +D+F E+GF +TS KEN I+EA L++KM+
Sbjct: 121 LLLANK--CDLSPWAVSRDQIDRFSKENGFTGWTETSVKENKNINEAMRVLIEKMM 174
>sp|O94655|YPT7_SCHPO Ras-related protein ypt7
Length = 205
Score = 131 bits (329), Expect = 1e-30
Identities = 70/165 (42%), Positives = 101/165 (61%)
Frame = +3
Query: 24 EKEYLFKVRVIGELGAGKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRLQLW 203
+K++L KV ++GE G GKTSI+ +YV++ FS+ Y+ATIG DF K + DD VV LQLW
Sbjct: 4 KKKHLLKVIILGESGVGKTSIMNQYVNRKFSKDYKATIGADFLTKEVLVDDK-VVTLQLW 62
Query: 204 DIAGQERFGNMLRVYYKDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIPCIL 383
D AGQERF ++ +Y+ A +VYDV + +FE + W+ + + + N + P IL
Sbjct: 63 DTAGQERFQSLGVAFYRGADCCVLVYDVNNSKSFETLDSWRDEFLIQASPSNPETFPFIL 122
Query: 384 LGNKSDCEREGRLSDTNYLDQFVNEHGFVKRFDTSAKENIGIDEA 518
LGNK D E + R+ + F G + F+TSAKE I + EA
Sbjct: 123 LGNKVDVEEQKRMVSKSKALAFCQARGEIPYFETSAKEAINVQEA 167
>sp|Q9C2L8|RAB7_NEUCR Probable Ras-related protein Rab7
Length = 205
Score = 124 bits (310), Expect = 2e-28
Identities = 65/175 (37%), Positives = 101/175 (57%)
Frame = +3
Query: 21 TEKEYLFKVRVIGELGAGKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRLQL 200
+ K+ L KV ++G+ G GKTS++ +YV+K FS Y+ATIG DF + + DD V +QL
Sbjct: 3 SRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSASYKATIGADFLTREVLVDDRQVT-MQL 61
Query: 201 WDIAGQERFGNMLRVYYKDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIPCI 380
WD AGQERF ++ +Y+ A +VYDV + +F+A+ W+ + + + + D P +
Sbjct: 62 WDTAGQERFQSLGVAFYRGADCCVLVYDVNNSKSFDALDSWRDEFLIQASPRDPDNFPFV 121
Query: 381 LLGNKSDCEREGRLSDTNYLDQFVNEHGFVKRFDTSAKENIGIDEAANALVDKML 545
+LGNK D E R+ T F G + F+TSAKE I +++A + L
Sbjct: 122 VLGNKIDMEESKRVISTKRAMTFCQSKGNIPYFETSAKEAINVEQAFEVIARNAL 176
>sp|P32939|YPT7_YEAST GTP-binding protein YPT7
Length = 208
Score = 120 bits (302), Expect = 2e-27
Identities = 61/166 (36%), Positives = 93/166 (56%)
Frame = +3
Query: 21 TEKEYLFKVRVIGELGAGKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRLQL 200
+ K+ + KV ++G+ G GKTS++ RYV+ +SQ Y+ATIG DF K + D V +Q+
Sbjct: 3 SRKKNILKVIILGDSGVGKTSLMHRYVNDKYSQQYKATIGADFLTKEVTVDGDKVATMQV 62
Query: 201 WDIAGQERFGNMLRVYYKDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIPCI 380
WD AGQERF ++ +Y+ A +VYDVT AS+FE + W+ + + + P +
Sbjct: 63 WDTAGQERFQSLGVAFYRGADCCVLVYDVTNASSFENIKSWRDEFLVHANVNSPETFPFV 122
Query: 381 LLGNKSDCEREGRLSDTNYLDQFVNEHGFVKRFDTSAKENIGIDEA 518
+LGNK D E ++ + G + F TSAK I +D A
Sbjct: 123 ILGNKIDAEESKKIVSEKSAQELAKSLGDIPLFLTSAKNAINVDTA 168
>sp|P36411|RAB7_DICDI Ras-related protein Rab7
Length = 203
Score = 120 bits (300), Expect = 3e-27
Identities = 66/166 (39%), Positives = 98/166 (59%)
Frame = +3
Query: 21 TEKEYLFKVRVIGELGAGKTSIIKRYVHKFFSQHYRATIGVDFALKVLPWDDSSVVRLQL 200
T+K+ L KV ++G+ G GKTS++ +YV+K FS Y+ATIG DF K L DD VV +Q+
Sbjct: 3 TKKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKELMVDDR-VVTMQI 61
Query: 201 WDIAGQERFGNMLRVYYKDAMGAFIVYDVTRASTFEAVVKWKKDLDSKVTQPNGDPIPCI 380
WD AGQERF ++ +Y+ A + YDV A TFE + W+ + + + D P +
Sbjct: 62 WDTAGQERFQSLGVAFYRGADCCVLCYDVNVAKTFENLDSWRDEFLIQAGPRDPDNFPFV 121
Query: 381 LLGNKSDCEREGRLSDTNYLDQFVNEHGFVKRFDTSAKENIGIDEA 518
+LGNK D E + R+ + G + F+TSAKE I +++A
Sbjct: 122 VLGNKIDLENQ-RVVSQKRAASWCQSKGNIPYFETSAKEAINVEQA 166
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,517,823
Number of Sequences: 369166
Number of extensions: 1353541
Number of successful extensions: 5287
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4645
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4773
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 3783975580
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)