Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_021_O15
(550 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8TE73|DYH5_HUMAN Ciliary dynein heavy chain 5 (Axonemal... 170 2e-42
sp|Q8VHE6|DYH5_MOUSE Ciliary dynein heavy chain 5 (Axonemal... 169 4e-42
sp|P23098|DYHC_TRIGR Dynein beta chain, ciliary 88 2e-17
sp|P39057|DYHC_ANTCR Dynein beta chain, ciliary 88 2e-17
sp|Q9NYC9|DYH9_HUMAN Ciliary dynein heavy chain 9 (Axonemal... 82 1e-15
sp|Q39575|DYHG_CHLRE Dynein gamma chain, flagellar outer arm 79 7e-15
sp|Q9MBF8|DYH1B_CHLRE Dynein 1-beta heavy chain, flagellar ... 74 2e-13
sp|Q96DT5|DYH11_HUMAN Ciliary dynein heavy chain 11 (Axonem... 74 3e-13
sp|Q39565|DYHB_CHLRE Dynein beta chain, flagellar outer arm 73 5e-13
sp|Q9SMH3|DYH1A_CHLRE Dynein 1-alpha heavy chain, flagellar... 72 9e-13
>sp|Q8TE73|DYH5_HUMAN Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5)
(HL1)
Length = 4624
Score = 170 bits (431), Expect = 2e-42
Identities = 88/138 (63%), Positives = 103/138 (74%)
Frame = +2
Query: 2 AMRQEVTRAHKGWALDTVVLWNDVTKHMHDEINQPPSEGVYVYGLYLEGAGWDKRNSKLM 181
AMRQE+TRA+KGWALD +VL N+VTK M D+I+ PP+EGVYVYGLYLEGAGWDKRN KL+
Sbjct: 4494 AMRQEITRANKGWALDNMVLCNEVTKWMKDDISAPPTEGVYVYGLYLEGAGWDKRNMKLI 4553
Query: 182 ESKSKVLFELLPVIHIQAIDISKEGEIPKDLLKNMYQCPVYKKPRRTDLTFIASVYLRCP 361
ESK KVLFEL+PVI I A E +D Y CP+YKKP RTDL +IA+V LR
Sbjct: 4554 ESKPKVLFELMPVIRIYA-----ENNTLRD--PRFYSCPIYKKPVRTDLNYIAAVDLR-- 4604
Query: 362 PIKQADHWTLRAVALLCD 415
+ +HW LR VALLCD
Sbjct: 4605 TAQTPEHWVLRGVALLCD 4622
>sp|Q8VHE6|DYH5_MOUSE Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5)
(Mdnah5)
Length = 4621
Score = 169 bits (428), Expect = 4e-42
Identities = 87/138 (63%), Positives = 104/138 (75%)
Frame = +2
Query: 2 AMRQEVTRAHKGWALDTVVLWNDVTKHMHDEINQPPSEGVYVYGLYLEGAGWDKRNSKLM 181
AMRQE+TRA+KGWALD +VL N+VTK M D+I+ PP+EGVYVYGLYLEGAGWDKRN KL+
Sbjct: 4491 AMRQEITRANKGWALDNMVLCNEVTKFMKDDISAPPTEGVYVYGLYLEGAGWDKRNMKLI 4550
Query: 182 ESKSKVLFELLPVIHIQAIDISKEGEIPKDLLKNMYQCPVYKKPRRTDLTFIASVYLRCP 361
ESK KVLFEL+PVI I A E +D +Y CP+YKKP RTDL +IA+V L+
Sbjct: 4551 ESKPKVLFELMPVIRIFA-----ENNTARD--PRLYCCPIYKKPVRTDLNYIAAVDLK-- 4601
Query: 362 PIKQADHWTLRAVALLCD 415
+ +HW LR VALLCD
Sbjct: 4602 TAQAPEHWVLRGVALLCD 4619
>sp|P23098|DYHC_TRIGR Dynein beta chain, ciliary
Length = 4466
Score = 87.8 bits (216), Expect = 2e-17
Identities = 51/136 (37%), Positives = 81/136 (59%)
Frame = +2
Query: 2 AMRQEVTRAHKGWALDTVVLWNDVTKHMHDEINQPPSEGVYVYGLYLEGAGWDKRNSKLM 181
A+ Q + R ++ W LD + L DVTK ++ + P EG YV+GL++EGA WD + + +
Sbjct: 4338 AIMQSMARKNE-WPLDKMCLQCDVTKKNKEDFSSApreGSYVHGLFMEGARWDTQTNMIA 4396
Query: 182 ESKSKVLFELLPVIHIQAIDISKEGEIPKDLLKNMYQCPVYKKPRRTDLTFIASVYLRCP 361
+++ K L +PVI I+AI + K+ +N+Y+CPVYK +R TF+ + L+
Sbjct: 4397 DARLKELAPNMPVIFIKAIPVDKQD------TRNIYECPVYKTKQRGP-TFVWTFNLKSK 4449
Query: 362 PIKQADHWTLRAVALL 409
++A WTL VALL
Sbjct: 4450 --EKAAKWTLAGVALL 4463
>sp|P39057|DYHC_ANTCR Dynein beta chain, ciliary
Length = 4466
Score = 87.8 bits (216), Expect = 2e-17
Identities = 51/136 (37%), Positives = 81/136 (59%)
Frame = +2
Query: 2 AMRQEVTRAHKGWALDTVVLWNDVTKHMHDEINQPPSEGVYVYGLYLEGAGWDKRNSKLM 181
A+ Q + R ++ W LD + L DVTK ++ + P EG YV+GL++EGA WD + + +
Sbjct: 4338 AIMQSMARKNE-WPLDKMCLQCDVTKKNKEDFSSApreGSYVHGLFMEGARWDTQTNMIA 4396
Query: 182 ESKSKVLFELLPVIHIQAIDISKEGEIPKDLLKNMYQCPVYKKPRRTDLTFIASVYLRCP 361
+++ K L +PVI I+AI + K+ +N+Y+CPVYK +R TF+ + L+
Sbjct: 4397 DARLKELAPNMPVIFIKAIPVDKQD------TRNIYECPVYKTKQRGP-TFVWTFNLKSK 4449
Query: 362 PIKQADHWTLRAVALL 409
++A WTL VALL
Sbjct: 4450 --EKAAKWTLAGVALL 4463
>sp|Q9NYC9|DYH9_HUMAN Ciliary dynein heavy chain 9 (Axonemal beta dynein heavy chain 9)
Length = 4486
Score = 81.6 bits (200), Expect = 1e-15
Identities = 48/136 (35%), Positives = 74/136 (54%)
Frame = +2
Query: 2 AMRQEVTRAHKGWALDTVVLWNDVTKHMHDEINQPPSEGVYVYGLYLEGAGWDKRNSKLM 181
A+ Q R ++ W LD + L D+TK +E PP EG Y++GL++EGA WD + +
Sbjct: 4358 AIMQSTARKNE-WPLDQIALQCDMTKKNREEFRSPpreGAYIHGLFMEGACWDTQAGIIT 4416
Query: 182 ESKSKVLFELLPVIHIQAIDISKEGEIPKDLLKNMYQCPVYKKPRRTDLTFIASVYLRCP 361
E+K K L +PV+ I+AI K+ +++Y CPVYK +R T++ + L+
Sbjct: 4417 EAKLKDLTPPMPVMFIKAIPADKQD------CRSVYSCPVYKTSQRGP-TYVWTFNLKTK 4469
Query: 362 PIKQADHWTLRAVALL 409
+ W L VALL
Sbjct: 4470 --ENPSKWVLAGVALL 4483
>sp|Q39575|DYHG_CHLRE Dynein gamma chain, flagellar outer arm
Length = 4485
Score = 79.0 bits (193), Expect = 7e-15
Identities = 55/142 (38%), Positives = 78/142 (54%), Gaps = 5/142 (3%)
Frame = +2
Query: 2 AMRQEVTRAHKG-WALDTVVLWNDVTKHMHD--EINQPPSEGVYVYGLYLEGAGWDKRNS 172
AM+QEV R H+ WALD VV+ ++VT D + + EGVYVYGLYL+ D R +
Sbjct: 4351 AMKQEVNRKHRDKWALDDVVMSSEVTHRPKDFESLKEGAPEGVYVYGLYLD-LRLDGREN 4409
Query: 173 KLMESKSKVLFELLPVIHIQAIDISKEGEIPKDLLKN-MYQCP-VYKKPRRTDLTFIASV 346
+LM+S K LF LPV+H+ +G + KD ++ +Y+ P Y+ R L FI +
Sbjct: 4410 RLMDSDPKKLFNPLPVLHV-------DGVLAKDKKRSGLYEAPKPYRVKARKGLNFITTF 4462
Query: 347 YLRCPPIKQADHWTLRAVALLC 412
+R K W L V +LC
Sbjct: 4463 SVRTEDDK--SKWILPGVGILC 4482
>sp|Q9MBF8|DYH1B_CHLRE Dynein 1-beta heavy chain, flagellar inner arm I1 complex (1-beta
DHC) (Dynein 1, subspecies f)
Length = 4513
Score = 73.9 bits (180), Expect = 2e-13
Identities = 44/110 (40%), Positives = 57/110 (51%), Gaps = 4/110 (3%)
Frame = +2
Query: 92 EINQPPSEGVYVYGLYLEGAGWDKRNSKLMESKSKVLFELLPVIHIQAIDISKEGEIPKD 271
EIN PP EGVY+ GL+LEGAGWD N L E L +P++ + + E K
Sbjct: 4406 EINAPPKEGVYIKGLFLEGAGWDFENGCLCEPNPMELIVPMPILLFRPV------ENKKR 4459
Query: 272 LLKNMYQCPVYKKPRRTDL----TFIASVYLRCPPIKQADHWTLRAVALL 409
K +Y CP+Y P RT +F+ +V LR DHW +R ALL
Sbjct: 4460 TAKGIYTCPLYLYPLRTGTRERPSFMINVDLRSGS-ADPDHWIMRGTALL 4508
>sp|Q96DT5|DYH11_HUMAN Ciliary dynein heavy chain 11 (Axonemal beta dynein heavy chain 11)
Length = 4523
Score = 73.6 bits (179), Expect = 3e-13
Identities = 46/139 (33%), Positives = 73/139 (52%), Gaps = 1/139 (0%)
Frame = +2
Query: 2 AMRQEVTRAHKGWALDTVVLWNDVTKHMHDEINQPPSEGVYVYGLYLEGAGWDKRNSKLM 181
A+ Q + R ++ W LD L DVTK ++ PP EG Y++GL++EGA WD + ++
Sbjct: 4395 AIMQTMARKNE-WPLDKTRLTADVTKKTKEDYGHPpreGAYLHGLFMEGARWDTQAGTIV 4453
Query: 182 ESKSKVLFELLPVIHIQAIDISKEGEIPKDLLKNMYQCPVYKKPRRTDLTFIASVY-LRC 358
E++ K L +PVI +A + ++ K Y+CPVY RT L + ++ R
Sbjct: 4454 EARLKELACPMPVIFAKATPVDRQE------TKQTYECPVY----RTKLRGPSYIWTFRL 4503
Query: 359 PPIKQADHWTLRAVALLCD 415
++ W L VALL +
Sbjct: 4504 KSEEKTAKWVLAGVALLLE 4522
>sp|Q39565|DYHB_CHLRE Dynein beta chain, flagellar outer arm
Length = 4568
Score = 72.8 bits (177), Expect = 5e-13
Identities = 46/135 (34%), Positives = 68/135 (50%), Gaps = 1/135 (0%)
Frame = +2
Query: 14 EVTRAHKGWALDTVVLWNDVTKHMHDEINQPPSEGVYVYGLYLEGAGWDKRNSKLMESKS 193
+ T W LD V+ +VTK D+I +G +++GL LEGA WD + L +SK
Sbjct: 4442 QATARRNDWPLDKTVIITEVTKKQPDQIEANSRDGAFIHGLTLEGARWDDKIGALDDSKP 4501
Query: 194 KVLFELLPVIHIQAIDISKEGEIPKDLLKNMYQCPVY-KKPRRTDLTFIASVYLRCPPIK 370
K LF +PVI ++A+ K +K++Y+CPVY + R + F A + + IK
Sbjct: 4502 KELFCPMPVILVRAVTQDKAE------MKDVYKCPVYTTEARFREEVFEAQLKSKHTEIK 4555
Query: 371 QADHWTLRAVALLCD 415
W L V L D
Sbjct: 4556 ----WVLAGVCLFLD 4566
>sp|Q9SMH3|DYH1A_CHLRE Dynein 1-alpha heavy chain, flagellar inner arm I1 complex (1-alpha
DHC) (Dynein 1, subspecies f)
Length = 4625
Score = 72.0 bits (175), Expect = 9e-13
Identities = 43/128 (33%), Positives = 65/128 (50%), Gaps = 2/128 (1%)
Frame = +2
Query: 32 KGWALDTVVLWNDVTKHMHD-EINQPPSEGVYVYGLYLEGAGWDKRNSKLMESKSKVLFE 208
KGW LD L+ VTK ++++ P G Y+ GLYLEGA WD S+L + KVL
Sbjct: 4499 KGWPLDKSTLYTKVTKFTDPYQVSERPKYGCYMSGLYLEGAAWDLEASQLRKQDPKVLVN 4558
Query: 209 LLPVIHIQAIDISKEGEIPKDLLKNMYQCPVYKKPRRTDLTFIASVY-LRCPPIKQADHW 385
LP++ + I+ +K L N ++ PVY R + + V+ + + HW
Sbjct: 4559 ELPILQVIPIEANKL------KLANTFRAPVYVTQARRNAMGVGLVFDADLASAEHSSHW 4612
Query: 386 TLRAVALL 409
L+ VAL+
Sbjct: 4613 VLQGVALV 4620
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,017,519
Number of Sequences: 369166
Number of extensions: 1260545
Number of successful extensions: 3104
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3047
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3090
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 3833118120
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)