Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_021_M14
(681 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q19673|TYR3_CAEEL Putative tyrosinase-like protein tyr-3... 115 8e-26
sp|Q20191|NAS13_CAEEL Zinc metalloproteinase nas-13 precurs... 67 6e-11
sp|Q9QXX0|JAG1_MOUSE Jagged-1 precursor (Jagged1) 65 1e-10
sp|P78504|JAG1_HUMAN Jagged-1 precursor (Jagged1) (hJ1) (CD... 65 1e-10
sp|Q63722|JAG1_RAT Jagged-1 precursor (Jagged1) 65 1e-10
sp|Q90Y54|JAG1B_BRARE Jagged-1b precursor (Jagged1b) (Jagged3) 64 3e-10
sp|P34269|TYR1_CAEEL Putative tyrosinase-like protein tyr-1... 60 5e-09
sp|P55115|NAS15_CAEEL Zinc metalloproteinase nas-15 precurs... 57 3e-08
sp|Q6DI48|DLLA_BRARE Delta-like protein A precursor (DeltaA... 57 4e-08
sp|Q9QYE5|JAG2_MOUSE Jagged-2 precursor (Jagged2) 55 2e-07
>sp|Q19673|TYR3_CAEEL Putative tyrosinase-like protein tyr-3 precursor
Length = 683
Score = 115 bits (289), Expect = 8e-26
Identities = 64/212 (30%), Positives = 88/212 (41%), Gaps = 36/212 (16%)
Frame = +1
Query: 40 NCLNSHESCDTWADRGECASNPGYMLVSCKKACNVC----GKENKCADYRKRCPIMAKYG 207
+C N +E C W+ +GEC NP YM V CK +C C +C+D C + ++ G
Sbjct: 461 SCFNENECCGPWSAKGECQKNPVYMNVWCKASCRQCTPNYNINEECSDRHTNCAMWSRSG 520
Query: 208 LCESDPRFMLQNCKESCGVC---------------------------DGSSKNRP----- 291
C +P +M +NC+ SC C + +N P
Sbjct: 521 ECNKNPLWMSENCRSSCQKCGRSRAATCGGGGGADSISNPTTMPPATNNGQQNTPCDSPM 580
Query: 292 CVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISDPNCKDLQIHCLYWAN 471
C + +Q C WA +C +NP +M CK SC CR + P C D C WA
Sbjct: 581 CYNEDQCCPIWAQRGQCRSNPGYMTCQCKVSCGVCRP---NYVYGP-CADYHYDCAAWAR 636
Query: 472 AGECQLNPGWAKQNCPFSCQHCGGCRDLIQNC 567
GEC N W +NC SC C + L C
Sbjct: 637 RGECLKNK-WMPENCRRSCNTCVNQQQLAARC 667
Score = 103 bits (258), Expect = 3e-22
Identities = 62/203 (30%), Positives = 89/203 (43%), Gaps = 35/203 (17%)
Frame = +1
Query: 145 CGKENKCADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSK-NRPCVDANQDCAG 321
C EN+C C + G C+ +P +M CK SC C + N C D + +CA
Sbjct: 462 CFNENEC------CGPWSAKGECQKNPVYMNVWCKASCRQCTPNYNINEECSDRHTNCAM 515
Query: 322 WAASHECETNPSWMLYNCKKSCNHCRDAR---------LESISDPN-------------- 432
W+ S EC NP WM NC+ SC C +R +SIS+P
Sbjct: 516 WSRSGECNKNPLWMSENCRSSCQKCGRSRAATCGGGGGADSISNPTTMPPATNNGQQNTP 575
Query: 433 -----CKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHC------GGCRDLIQNCQNFA 579
C + C WA G+C+ NPG+ C SC C G C D +C +A
Sbjct: 576 CDSPMCYNEDQCCPIWAQRGQCRSNPGYMTCQCKVSCGVCRPNYVYGPCADYHYDCAAWA 635
Query: 580 NQGYCKTNEVYMNQSCKKTCGFC 648
+G C N+ +M ++C+++C C
Sbjct: 636 RRGECLKNK-WMPENCRRSCNTC 657
Score = 77.4 bits (189), Expect = 3e-14
Identities = 34/81 (41%), Positives = 44/81 (54%), Gaps = 3/81 (3%)
Frame = +1
Query: 34 NPNCLNSHESCDTWADRGECASNPGYMLVSCKKACNVCGKE---NKCADYRKRCPIMAKY 204
+P C N + C WA RG+C SNPGYM CK +C VC CADY C A+
Sbjct: 578 SPMCYNEDQCCPIWAQRGQCRSNPGYMTCQCKVSCGVCRPNYVYGPCADYHYDCAAWARR 637
Query: 205 GLCESDPRFMLQNCKESCGVC 267
G C + ++M +NC+ SC C
Sbjct: 638 GECLKN-KWMPENCRRSCNTC 657
>sp|Q20191|NAS13_CAEEL Zinc metalloproteinase nas-13 precursor (Nematode astacin 13)
Length = 527
Score = 66.6 bits (161), Expect = 6e-11
Identities = 36/84 (42%), Positives = 41/84 (48%), Gaps = 5/84 (5%)
Frame = +1
Query: 160 KCADYRKRCPIMAKYGLCES--DPRFMLQNCKESCGVCDGSSKNRP-CVDANQDCAGWAA 330
KC D RK C +A+ G CES RFM +NC SCG C K + C DA C WA
Sbjct: 444 KCEDRRKDCEFLARAGHCESRFSIRFMTENCANSCGKCIAEEKRKEVCEDARTWCERWAN 503
Query: 331 SHECETN--PSWMLYNCKKSCNHC 396
S C +M C KSCN C
Sbjct: 504 SGMCNQTVFKDYMRQKCAKSCNFC 527
Score = 49.3 bits (116), Expect = 9e-06
Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 11/83 (13%)
Frame = +1
Query: 433 CKDLQIHCLYWANAGECQ--LNPGWAKQNCPFSCQHCGG-------CRDLIQNCQNFANQ 585
C+D + C + A AG C+ + + +NC SC C C D C+ +AN
Sbjct: 445 CEDRRKDCEFLARAGHCESRFSIRFMTENCANSCGKCIAEEKRKEVCEDARTWCERWANS 504
Query: 586 GYCKTN--EVYMNQSCKKTCGFC 648
G C + YM Q C K+C FC
Sbjct: 505 GMCNQTVFKDYMRQKCAKSCNFC 527
Score = 47.4 bits (111), Expect = 4e-05
Identities = 28/86 (32%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Frame = +1
Query: 292 CVDANQDCAGWAASHECETNPS--WMLYNCKKSCNHCRDARLESISDPNCKDLQIHCLYW 465
C D +DC A + CE+ S +M NC SC C E C+D + C W
Sbjct: 445 CEDRRKDCEFLARAGHCESRFSIRFMTENCANSCGKCI---AEEKRKEVCEDARTWCERW 501
Query: 466 ANAGECQ--LNPGWAKQNCPFSCQHC 537
AN+G C + + +Q C SC C
Sbjct: 502 ANSGMCNQTVFKDYMRQKCAKSCNFC 527
Score = 42.0 bits (97), Expect = 0.001
Identities = 25/83 (30%), Positives = 34/83 (40%), Gaps = 8/83 (9%)
Frame = +1
Query: 43 CLNSHESCDTWADRGECASNPG--YMLVSCKKACNVCGKENK----CADYRKRCPIMAKY 204
C + + C+ A G C S +M +C +C C E K C D R C A
Sbjct: 445 CEDRRKDCEFLARAGHCESRFSIRFMTENCANSCGKCIAEEKRKEVCEDARTWCERWANS 504
Query: 205 GLCESD--PRFMLQNCKESCGVC 267
G+C +M Q C +SC C
Sbjct: 505 GMCNQTVFKDYMRQKCAKSCNFC 527
Score = 31.2 bits (69), Expect = 2.6
Identities = 12/39 (30%), Positives = 23/39 (58%), Gaps = 2/39 (5%)
Frame = +1
Query: 538 GGCRDLIQNCQNFANQGYCKT--NEVYMNQSCKKTCGFC 648
G C D ++C+ A G+C++ + +M ++C +CG C
Sbjct: 443 GKCEDRRKDCEFLARAGHCESRFSIRFMTENCANSCGKC 481
>sp|Q9QXX0|JAG1_MOUSE Jagged-1 precursor (Jagged1)
Length = 1218
Score = 65.5 bits (158), Expect = 1e-10
Identities = 58/251 (23%), Positives = 92/251 (36%), Gaps = 44/251 (17%)
Frame = +1
Query: 31 SNPNCLNSHESC--DTWADRG---------ECASNPGYMLVSCKKACNVCGKENKCADYR 177
S PNC + +C D +RG EC +PG+ +C + C N +
Sbjct: 329 SGPNCEIAEHACLSDPCHNRGSCKETSSGFECECSPGWTGPTCSTNIDDCSPNN--CSHG 386
Query: 178 KRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPS 357
C + C P++ + C+ C+ +PCV+A + C AS+ C+ P
Sbjct: 387 GTCQDLVNGFKCVCPPQWTGKTCQLDANECEA----KPCVNA-RSCKNLIASYYCDCLPG 441
Query: 358 WMLYNCKKSCNHCRDARLESISDPNCKDLQI----------------------------- 450
WM NC + N C + +D +C+DL
Sbjct: 442 WMGQNCDININDCLG---QCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLN 498
Query: 451 --HCLYWANAGECQLNPGWAKQNCPFSCQHC--GGCRDLIQNCQNFANQGYCKTNEVYMN 618
HC N +C G++ C +C C++ Q C N A+ +CK E Y
Sbjct: 499 GGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQ-CYNRASDYFCKCPEDYEG 557
Query: 619 QSCKKTCGFCR 651
++C CR
Sbjct: 558 KNCSHLKDHCR 568
Score = 55.5 bits (132), Expect = 1e-07
Identities = 46/190 (24%), Positives = 71/190 (37%), Gaps = 7/190 (3%)
Frame = +1
Query: 43 CLNSHESCDTWADRGECASNPGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESD 222
CLN +T D+ +C+ GY +C+ A + C + C + R C + CE
Sbjct: 306 CLNRGTCSNTGPDKYQCSCPEGYSGPNCEIAEHAC-LSDPCHN-RGSCKETSSGFECECS 363
Query: 223 PRFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRD 402
P + C + C ++ + C +C P W C+ N C
Sbjct: 364 PGWTGPTCSTNIDDCSPNNCSH-----GGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA 418
Query: 403 ARLESISDPNCKDLQIHCLYWANAGECQLNPGWAKQNCPFS-------CQHCGGCRDLIQ 561
++ +CK+L I Y C PGW QNC + CQ+ CRDL+
Sbjct: 419 K--PCVNARSCKNL-IASYY------CDCLPGWMGQNCDININDCLGQCQNDASCRDLVN 469
Query: 562 NCQNFANQGY 591
+ GY
Sbjct: 470 GYRCICPPGY 479
Score = 38.1 bits (87), Expect = 0.021
Identities = 38/172 (22%), Positives = 61/172 (35%), Gaps = 9/172 (5%)
Frame = +1
Query: 139 NVCGKENKCADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSKNRPCVDANQDCA 318
NVCG KC K+ C+ + F C E+ C+ + PC + C
Sbjct: 597 NVCGPHGKCKSQSG-----GKF-TCDCNKGFTGTYCHENINDCESN----PCKNGGT-CI 645
Query: 319 GWAASHECETNPSWMLYNCKKSCNHCRDARLESISDPNCKDLQIHCLYWANAGECQLNPG 498
S++C + W +C+ + N C ++ C+DL N C G
Sbjct: 646 DGVNSYKCICSDGWEGAHCENNINDC--SQNPCHYGGTCRDL-------VNDFYCDCKNG 696
Query: 499 WAKQNC--------PFSCQHCGGCRDLIQNCQNFANQGYCKTN-EVYMNQSC 627
W + C +C + G C D + + G+ T + N SC
Sbjct: 697 WKGKTCHSRDSQCDEATCNNGGTCYDEVDTFKCMCPGGWEGTTCNIARNSSC 748
Score = 31.2 bits (69), Expect = 2.6
Identities = 28/129 (21%), Positives = 44/129 (34%), Gaps = 9/129 (6%)
Frame = +1
Query: 61 SCDTWADRGECASNPGYMLVSCKKACNVCGK---------ENKCADYRKRCPIMAKYGLC 213
SC + C PGY C++ + C +N+ ++ CP LC
Sbjct: 463 SCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLC 522
Query: 214 ESDPRFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNH 393
+ D + N PC + Q C A+ + C+ + NC +H
Sbjct: 523 QLDIDYCEPN---------------PCQNGAQ-CYNRASDYFCKCPEDYEGKNCSHLKDH 566
Query: 394 CRDARLESI 420
CR E I
Sbjct: 567 CRTTTCEVI 575
>sp|P78504|JAG1_HUMAN Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen)
Length = 1218
Score = 65.5 bits (158), Expect = 1e-10
Identities = 58/251 (23%), Positives = 92/251 (36%), Gaps = 44/251 (17%)
Frame = +1
Query: 31 SNPNCLNSHESC--DTWADRG---------ECASNPGYMLVSCKKACNVCGKENKCADYR 177
S PNC + +C D +RG EC +PG+ +C + C N +
Sbjct: 329 SGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNN--CSHG 386
Query: 178 KRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPS 357
C + C P++ + C+ C+ +PCV+A + C AS+ C+ P
Sbjct: 387 GTCQDLVNGFKCVCPPQWTGKTCQLDANECEA----KPCVNA-KSCKNLIASYYCDCLPG 441
Query: 358 WMLYNCKKSCNHCRDARLESISDPNCKDLQI----------------------------- 450
WM NC + N C + +D +C+DL
Sbjct: 442 WMGQNCDININDCLG---QCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLN 498
Query: 451 --HCLYWANAGECQLNPGWAKQNCPFSCQHC--GGCRDLIQNCQNFANQGYCKTNEVYMN 618
HC N +C G++ C +C C++ Q C N A+ +CK E Y
Sbjct: 499 GGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQ-CYNRASDYFCKCPEDYEG 557
Query: 619 QSCKKTCGFCR 651
++C CR
Sbjct: 558 KNCSHLKDHCR 568
Score = 55.5 bits (132), Expect = 1e-07
Identities = 46/190 (24%), Positives = 71/190 (37%), Gaps = 7/190 (3%)
Frame = +1
Query: 43 CLNSHESCDTWADRGECASNPGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESD 222
CLN +T D+ +C+ GY +C+ A + C + C + R C + CE
Sbjct: 306 CLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHAC-LSDPCHN-RGSCKETSLGFECECS 363
Query: 223 PRFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRD 402
P + C + C ++ + C +C P W C+ N C
Sbjct: 364 PGWTGPTCSTNIDDCSPNNCSH-----GGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA 418
Query: 403 ARLESISDPNCKDLQIHCLYWANAGECQLNPGWAKQNCPFS-------CQHCGGCRDLIQ 561
++ +CK+L I Y C PGW QNC + CQ+ CRDL+
Sbjct: 419 K--PCVNAKSCKNL-IASYY------CDCLPGWMGQNCDININDCLGQCQNDASCRDLVN 469
Query: 562 NCQNFANQGY 591
+ GY
Sbjct: 470 GYRCICPPGY 479
Score = 31.2 bits (69), Expect = 2.6
Identities = 48/237 (20%), Positives = 81/237 (34%), Gaps = 40/237 (16%)
Frame = +1
Query: 61 SCDTWADRGECASNPGYMLVSCKKACNVCGK---------ENKCADYRKRCPIMAKYGLC 213
SC + C PGY C++ + C +N+ ++ CP LC
Sbjct: 463 SCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLC 522
Query: 214 ESDPRFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNH 393
+ D + N PC + Q C A+ + C+ + NC +H
Sbjct: 523 QLDIDYCEPN---------------PCQNGAQ-CYNRASDYFCKCPEDYEGKNCSHLKDH 566
Query: 394 CRDARLESI--------SDPNCKDLQI--------HCLYWANAG---ECQLNPGWAKQNC 516
CR E I S+ + ++ H + +G C N G+ C
Sbjct: 567 CRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYC 626
Query: 517 PFS--------CQHCGGCRDLIQNCQNFANQG----YCKTNEVYMNQSCKKTCGFCR 651
+ C++ G C D + + + + G YC+TN +Q+ G CR
Sbjct: 627 HENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCR 683
>sp|Q63722|JAG1_RAT Jagged-1 precursor (Jagged1)
Length = 1219
Score = 65.5 bits (158), Expect = 1e-10
Identities = 58/251 (23%), Positives = 92/251 (36%), Gaps = 44/251 (17%)
Frame = +1
Query: 31 SNPNCLNSHESC--DTWADRG---------ECASNPGYMLVSCKKACNVCGKENKCADYR 177
S PNC + +C D +RG EC +PG+ +C + C N +
Sbjct: 329 SGPNCEIAEHACLSDPCHNRGSCKETSSGFECECSPGWTGPTCSTNIDDCSPNN--CSHG 386
Query: 178 KRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPS 357
C + C P++ + C+ C+ +PCV+A + C AS+ C+ P
Sbjct: 387 GTCQDLVNGFKCVCPPQWTGKTCQLDANECEA----KPCVNA-RSCKNLIASYYCDCLPG 441
Query: 358 WMLYNCKKSCNHCRDARLESISDPNCKDLQI----------------------------- 450
WM NC + N C + +D +C+DL
Sbjct: 442 WMGQNCDININDCLG---QCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLN 498
Query: 451 --HCLYWANAGECQLNPGWAKQNCPFSCQHC--GGCRDLIQNCQNFANQGYCKTNEVYMN 618
HC N +C G++ C +C C++ Q C N A+ +CK E Y
Sbjct: 499 GGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQ-CYNRASDYFCKCPEDYEG 557
Query: 619 QSCKKTCGFCR 651
++C CR
Sbjct: 558 KNCSHLKDHCR 568
Score = 55.5 bits (132), Expect = 1e-07
Identities = 46/190 (24%), Positives = 71/190 (37%), Gaps = 7/190 (3%)
Frame = +1
Query: 43 CLNSHESCDTWADRGECASNPGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESD 222
CLN +T D+ +C+ GY +C+ A + C + C + R C + CE
Sbjct: 306 CLNRGTCSNTGPDKYQCSCPEGYSGPNCEIAEHAC-LSDPCHN-RGSCKETSSGFECECS 363
Query: 223 PRFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRD 402
P + C + C ++ + C +C P W C+ N C
Sbjct: 364 PGWTGPTCSTNIDDCSPNNCSH-----GGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA 418
Query: 403 ARLESISDPNCKDLQIHCLYWANAGECQLNPGWAKQNCPFS-------CQHCGGCRDLIQ 561
++ +CK+L I Y C PGW QNC + CQ+ CRDL+
Sbjct: 419 K--PCVNARSCKNL-IASYY------CDCLPGWMGQNCDININDCLGQCQNDASCRDLVN 469
Query: 562 NCQNFANQGY 591
+ GY
Sbjct: 470 GYRCICPPGY 479
Score = 41.6 bits (96), Expect = 0.002
Identities = 46/218 (21%), Positives = 76/218 (34%), Gaps = 23/218 (10%)
Frame = +1
Query: 43 CLNSHESCDTWADRGECASNPGYMLVSCKKAC--------------NVCGKENKCADYRK 180
C +E + + C + P ++ SC A NVCG KC
Sbjct: 551 CPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKC----- 605
Query: 181 RCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSW 360
+ K+ C+ + F C E+ C+G+ PC + C S++C + W
Sbjct: 606 KSESGGKF-TCDCNKGFTGTYCHENINDCEGN----PCTNGGT-CIDGVNSYKCICSDGW 659
Query: 361 MLYNCKKSCNHCRDARLESISDPNCKDLQIHCLYWANAGECQLNPGWAKQNC-------- 516
+C+ + N C ++ C+DL N C GW + C
Sbjct: 660 EGAHCENNINDC--SQNPCHYGGTCRDL-------VNDFYCDCKNGWKGKTCHSRDSQCD 710
Query: 517 PFSCQHCGGCRDLIQNCQNFANQGYCKTN-EVYMNQSC 627
+C + G C D + + G+ T + N SC
Sbjct: 711 EATCNNGGTCYDEVDTFKCMCPGGWEGTTCNIARNSSC 748
Score = 30.8 bits (68), Expect = 3.4
Identities = 28/129 (21%), Positives = 44/129 (34%), Gaps = 9/129 (6%)
Frame = +1
Query: 61 SCDTWADRGECASNPGYMLVSCKKACNVCGK---------ENKCADYRKRCPIMAKYGLC 213
SC + C PGY C++ + C +N+ ++ CP LC
Sbjct: 463 SCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLC 522
Query: 214 ESDPRFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNH 393
+ D + N PC + Q C A+ + C+ + NC +H
Sbjct: 523 QLDIDYCEPN---------------PCQNGAQ-CYNRASDYFCKCPEDYEGKNCSHLKDH 566
Query: 394 CRDARLESI 420
CR E I
Sbjct: 567 CRTTPCEVI 575
>sp|Q90Y54|JAG1B_BRARE Jagged-1b precursor (Jagged1b) (Jagged3)
Length = 1213
Score = 64.3 bits (155), Expect = 3e-10
Identities = 55/241 (22%), Positives = 87/241 (36%), Gaps = 38/241 (15%)
Frame = +1
Query: 43 CLNSHESCDTWADRGECASNPGYMLVSCKKACNVCGKENKCAD----------YRKRC-- 186
CLN +T D+ +C+ GY V+C++A + C N CA+ Y C
Sbjct: 303 CLNGGTCSNTGPDKYQCSCEDGYSGVNCERAEHAC-LSNPCANGGTCKETSQGYECHCAI 361
Query: 187 ---------------PIMAKYG----------LCESDPRFMLQNCKESCGVCDGSSKNRP 291
P K+G C P + + C+ C+ ++P
Sbjct: 362 GWSGTSCEINVDDCTPNQCKHGGTCQDLVNGFKCACPPHWTGKTCQIDANECE----DKP 417
Query: 292 CVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISDPNCKDLQIHCLYWAN 471
CV+A + C ++ CE P W NC + N C+ + ++ CKDL N
Sbjct: 418 CVNA-KSCHNLIGAYFCECLPGWSGQNCDININDCKG---QCLNGGTCKDL-------VN 466
Query: 472 AGECQLNPGWAKQNCPFSCQHCGGCRDLI-QNCQNFANQGYCKTNEVYMNQSCKKTCGFC 648
C PG+ + C C L CQ+ N C + Q C+ +C
Sbjct: 467 GYRCLCPPGYTGEQCEKDVDECASSPCLNGGRCQDEVNGFQCLCPAGFSGQLCQLDIDYC 526
Query: 649 R 651
+
Sbjct: 527 K 527
Score = 33.1 bits (74), Expect = 0.69
Identities = 50/239 (20%), Positives = 83/239 (34%), Gaps = 24/239 (10%)
Frame = +1
Query: 4 CQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYMLVSCKKACNVCGKENKCADYRKR 183
C+ D S+P CLN C + +C G+ C+ + C K N C + +
Sbjct: 481 CEKDVDECASSP-CLNGGR-CQDEVNGFQCLCPAGFSGQLCQLDIDYC-KPNPCQN-GAQ 536
Query: 184 CPIMAKYGLCESDPRFMLQNCKE--------SCGVCDG-----SSKNRP----------C 294
C +A C+ + +NC SC V D +S + P C
Sbjct: 537 CFNLASDYFCKCPDDYEGKNCSHLKDHCRTTSCQVIDSCTVAVASNSTPEGVRYISSNVC 596
Query: 295 VDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISDPNCKDLQIHCLYWANA 474
+ + CE + C ++ N C S+P C++ C+ N
Sbjct: 597 GPHGRCRSQAGGQFTCECQEGFRGTYCHENINDCE-------SNP-CRNGGT-CIDKVNV 647
Query: 475 GECQLNPGWAKQNCPFSCQHCGGCRDLIQN-CQNFANQGYCKTNEVYMNQSCKKTCGFC 648
+C GW +C + C L + CQ+ N YC+ + ++C C
Sbjct: 648 YQCICADGWEGVHCEINIDDCSLNPCLNKGACQDLVNDFYCECRNGWKGKTCHSRDSQC 706
Score = 32.3 bits (72), Expect = 1.2
Identities = 25/119 (21%), Positives = 45/119 (37%)
Frame = +1
Query: 49 NSHESCDTWADRGECASNPGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESDPR 228
N+ +C D +C +PG+ +C A N N C + C + C
Sbjct: 712 NNGGTCHDEGDTFKCRCSPGWEGATCNIAKNSSCLPNPC-ENGGTCVVNGDSFNCVCKEG 770
Query: 229 FMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDA 405
+ C E+ C+ PC ++ C + CE P + +C+ + N C+ +
Sbjct: 771 WEGSTCTENTNDCN----PHPCYNSG-TCVDGENWYRCECAPGFAGPDCRININECQSS 824
>sp|P34269|TYR1_CAEEL Putative tyrosinase-like protein tyr-1 precursor
Length = 601
Score = 60.1 bits (144), Expect = 5e-09
Identities = 23/81 (28%), Positives = 40/81 (49%)
Frame = +1
Query: 154 ENKCADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAAS 333
++ C + C ++ C ++ +M + C++SCG+C + NR C D + CA W
Sbjct: 477 QSNCYNEDPCCNQWSRQNECRTNTVYMNRYCRKSCGLCQSNDNNRGCHDRHISCAYWRGQ 536
Query: 334 HECETNPSWMLYNCKKSCNHC 396
+ C WM NC+ +C C
Sbjct: 537 NFCTRRRQWMAENCQATCGWC 557
Score = 58.9 bits (141), Expect = 1e-08
Identities = 29/98 (29%), Positives = 43/98 (43%)
Frame = +1
Query: 292 CVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISDPNCKDLQIHCLYWAN 471
C + + C W+ +EC TN +M C+KSC C+ + ++ C D I C YW
Sbjct: 480 CYNEDPCCNQWSRQNECRTNTVYMNRYCRKSCGLCQ----SNDNNRGCHDRHISCAYWRG 535
Query: 472 AGECQLNPGWAKQNCPFSCQHCGGCRDLIQNCQNFANQ 585
C W +NC +C C + Q C + A Q
Sbjct: 536 QNFCTRRRQWMAENCQATCGWCN--MNEAQLCASVARQ 571
Score = 57.0 bits (136), Expect = 4e-08
Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +1
Query: 40 NCLNSHESCDTWADRGECASNPGYMLVSCKKACNVCGKENK---CADYRKRCPIMAKYGL 210
NC N C+ W+ + EC +N YM C+K+C +C + C D C
Sbjct: 479 NCYNEDPCCNQWSRQNECRTNTVYMNRYCRKSCGLCQSNDNNRGCHDRHISCAYWRGQNF 538
Query: 211 CESDPRFMLQNCKESCGVCD 270
C ++M +NC+ +CG C+
Sbjct: 539 CTRRRQWMAENCQATCGWCN 558
Score = 50.4 bits (119), Expect = 4e-06
Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 6/79 (7%)
Frame = +1
Query: 430 NCKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHCG------GCRDLIQNCQNFANQGY 591
NC + C W+ EC+ N + + C SC C GC D +C + Q +
Sbjct: 479 NCYNEDPCCNQWSRQNECRTNTVYMNRYCRKSCGLCQSNDNNRGCHDRHISCAYWRGQNF 538
Query: 592 CKTNEVYMNQSCKKTCGFC 648
C +M ++C+ TCG+C
Sbjct: 539 CTRRRQWMAENCQATCGWC 557
Score = 42.4 bits (98), Expect = 0.001
Identities = 14/29 (48%), Positives = 21/29 (72%)
Frame = +1
Query: 565 CQNFANQGYCKTNEVYMNQSCKKTCGFCR 651
C ++ Q C+TN VYMN+ C+K+CG C+
Sbjct: 487 CNQWSRQNECRTNTVYMNRYCRKSCGLCQ 515
>sp|P55115|NAS15_CAEEL Zinc metalloproteinase nas-15 precursor (Nematode astacin 15)
Length = 571
Score = 57.4 bits (137), Expect = 3e-08
Identities = 49/218 (22%), Positives = 72/218 (33%), Gaps = 53/218 (24%)
Frame = +1
Query: 43 CLNSHESCDTWADRGECASNPGYMLVSCKKACNVC--GKENK------------------ 162
C N CD A +G C NPG+M +C +C +C KE +
Sbjct: 354 CRNLRGDCDDLAKQGWCIRNPGWMRANCPISCGMCIPTKETQKPYVQTTTQAATTTARPQ 413
Query: 163 -----------------------CADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVC-- 267
C D R C ++ C+ FM C +SCG C
Sbjct: 414 KPVTQPIQPLPPVPPLPPTTPEDCEDLRVDCLVLVSQRYCKISQNFMKSYCAKSCGFCFK 473
Query: 268 ---DGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESIS----D 426
NRP V + + +P+ + K+ S
Sbjct: 474 PPPTEIPDNRPTVVTTRPLVTLPPAVIRSRSPAPPVSTTTKAAPTTSTTSAAPYSPTPLP 533
Query: 427 PNCKDLQIHCLYWANAGECQ-LNPGWAKQNCPFSCQHC 537
C D + C +W +AG C+ + + K+NCP SC C
Sbjct: 534 SECSDRKHFCSHWKSAGFCEGIFMNYMKKNCPASCGLC 571
Score = 52.8 bits (125), Expect = 8e-07
Identities = 31/118 (26%), Positives = 41/118 (34%), Gaps = 46/118 (38%)
Frame = +1
Query: 433 CKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHC------------------------- 537
C++L+ C A G C NPGW + NCP SC C
Sbjct: 354 CRNLRGDCDDLAKQGWCIRNPGWMRANCPISCGMCIPTKETQKPYVQTTTQAATTTARPQ 413
Query: 538 ---------------------GGCRDLIQNCQNFANQGYCKTNEVYMNQSCKKTCGFC 648
C DL +C +Q YCK ++ +M C K+CGFC
Sbjct: 414 KPVTQPIQPLPPVPPLPPTTPEDCEDLRVDCLVLVSQRYCKISQNFMKSYCAKSCGFC 471
Score = 51.2 bits (121), Expect = 2e-06
Identities = 35/131 (26%), Positives = 56/131 (42%), Gaps = 2/131 (1%)
Frame = +1
Query: 151 KENKCADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSK-NRPCVDANQDCAGWA 327
K ++C + R C +AK G C +P +M NC SCG+C + + +P V A
Sbjct: 350 KPSECRNLRGDCDDLAKQGWCIRNPGWMRANCPISCGMCIPTKETQKPYVQTTTQAATTT 409
Query: 328 A-SHECETNPSWMLYNCKKSCNHCRDARLESISDPNCKDLQIHCLYWANAGECQLNPGWA 504
A + T P L L + +C+DL++ CL + C+++ +
Sbjct: 410 ARPQKPVTQPIQPLPPVPP---------LPPTTPEDCEDLRVDCLVLVSQRYCKISQNFM 460
Query: 505 KQNCPFSCQHC 537
K C SC C
Sbjct: 461 KSYCAKSCGFC 471
>sp|Q6DI48|DLLA_BRARE Delta-like protein A precursor (DeltaA protein)
Length = 772
Score = 57.0 bits (136), Expect = 4e-08
Identities = 54/224 (24%), Positives = 81/224 (36%), Gaps = 9/224 (4%)
Frame = +1
Query: 7 QDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYMLVSCKKACNVCGKENKCADYRKRC 186
QD+ + P CLN +T C+ PG+ SC+ N C N C + C
Sbjct: 289 QDLNYCTHHKP-CLNGATCSNTGQGSYTCSCRPGFSGASCEIEVNEC-TGNPCRN-GGSC 345
Query: 187 PIMAKYGLCESDPRFMLQNCKESCGVC-DGSSKNRPCVDANQDCAGWAASHECETNPSWM 363
M C P F +NC+ S C DG PC + + + C+ +
Sbjct: 346 TDMENTYSCTCPPGFYGKNCELSAMTCADG-----PCFNGGRCADNPDGGYFCQCPTGYA 400
Query: 364 LYNCKKSCNHCRDARLESISDPNCKDLQIHCLYWANAGECQLNPGWAKQNCP-------- 519
+NC+K +HC S C + C+ N+ CQ G+ NC
Sbjct: 401 GFNCEKKIDHC--------SSSPCSN-GARCVDLVNSYLCQCPDGFTGMNCDRAGDECSM 451
Query: 520 FSCQHCGGCRDLIQNCQNFANQGYCKTNEVYMNQSCKKTCGFCR 651
+ CQ+ G CQ A+ C Y ++C C+
Sbjct: 452 YPCQNGG-------TCQEGASGYMCTCPPGYTGRNCSSPVSRCQ 488
>sp|Q9QYE5|JAG2_MOUSE Jagged-2 precursor (Jagged2)
Length = 1247
Score = 55.1 bits (131), Expect = 2e-07
Identities = 47/199 (23%), Positives = 72/199 (36%), Gaps = 12/199 (6%)
Frame = +1
Query: 31 SNPNCLNSHESCDTWADRGECASNPGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGL 210
S+ C+N + D+ CA GY+ +C++A + C N CA+ G
Sbjct: 313 SHHPCVNGGTCINAEPDQYLCACPDGYLGKNCERAEHACAS-NPCANG----------GS 361
Query: 211 CESDPRFMLQNCKE-----SCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNC 375
C P +C +C + + PC A C EC W+ C
Sbjct: 362 CHEVPSGFECHCPSGWSGPTCALDIDECASNPCA-AGGTCVDQVDGFECICPEQWVGATC 420
Query: 376 KKSCNHCRDARLESISDPNCKDLQIHCLYWANAGECQLNPGWAKQNCPFS-------CQH 534
+ N C ++ +CK+L C PGW NC + CQH
Sbjct: 421 QLDANECEGK--PCLNAFSCKNL-------IGGYYCDCLPGWKGINCQININDCHGQCQH 471
Query: 535 CGGCRDLIQNCQNFANQGY 591
G C+DL+ Q +G+
Sbjct: 472 GGTCKDLVNGYQCVCPRGF 490
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 84,129,399
Number of Sequences: 369166
Number of extensions: 1927743
Number of successful extensions: 6432
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5170
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6037
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 5782011865
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)