Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_021_M09
(879 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P37709|TRHY_RABIT Trichohyalin 63 1e-09
sp|P47460|HMW2_MYCGE Cytadherence high molecular weight pro... 60 6e-09
sp|P08799|MYS2_DICDI Myosin II heavy chain, non muscle 58 3e-08
sp|P22793|TRHY_SHEEP Trichohyalin 58 4e-08
sp|P46504|YLX8_CAEEL Hypothetical protein F23F12.8 in chrom... 56 2e-07
sp|Q07283|TRHY_HUMAN Trichohyalin 55 3e-07
sp|Q8K3M6|ERC2_RAT ERC protein 2 (CAZ-associated structural... 54 7e-07
sp|P53352|INCE_CHICK Inner centromere protein 53 1e-06
sp|Q6PH08|ERC2_MOUSE ERC protein 2 (CAZ-associated structur... 52 2e-06
sp|P53278|YG3A_YEAST Hypothetical 92.7 kDa protein in ASN2-... 52 2e-06
>sp|P37709|TRHY_RABIT Trichohyalin
Length = 1407
Score = 62.8 bits (151), Expect = 1e-09
Identities = 61/283 (21%), Positives = 134/283 (47%), Gaps = 8/283 (2%)
Frame = +3
Query: 6 EKIRKSKENVEFVKAQIKYNQQIKEKELKDWNVEGENIRRLAVAHALEKQRLDQIEREER 185
E+ RK +E + ++ + + +Q +E++L++ E + +RR E++R + E +
Sbjct: 625 ERERKLREEEQLLRQEEQELRQERERKLRE---EEQLLRREEQELRQERERKLREEEQLL 681
Query: 186 RFKMQEYMQQMDDVKKMREIDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXYDEKQNN 365
+ + +E +++ + +K+RE ++L +E+ E + E+
Sbjct: 682 QEREEERLRRQERARKLREEEQLLRQEEQELRQERERKLREEEQLLRREEQLLRQERDRK 741
Query: 366 LENIKNKL--SAQLKLKMDDEDLRIRNAIAEKEEKFQNDETDKEKKRQDTLKSIEDHRKN 539
L + L S + +L+ + + ++R E++ KF+ +E +++ ++ L+ E RK
Sbjct: 742 LREEEQLLQESEEERLRRQEREQQLRR---ERDRKFREEEQLLQEREEERLRRQERERK- 797
Query: 540 TMKALEEDQRLNKQRDLDSLLAR------KEADAILKENEDRRQKMRLTEAKKLAEEHLA 701
L E+++L ++R+ + L + +E + +L+E E+ R + + E K EE L
Sbjct: 798 ----LREEEQLLQEREEERLRRQERERKLREEEQLLQEREEERLRRQERERKLREEEQLL 853
Query: 702 TAKAIKDSDENSMMNKLKIMEENQKLLDLEESVFQEYARKVIE 830
++ E K+ EE Q L E+ + QE RK+ E
Sbjct: 854 R----QEEQELRQERARKLREEEQLLRQEEQELRQERDRKLRE 892
Score = 57.8 bits (138), Expect = 4e-08
Identities = 61/293 (20%), Positives = 129/293 (44%), Gaps = 22/293 (7%)
Frame = +3
Query: 18 KSKENVEFVKAQIKYNQQIKEKELKD-------WNVEGENIRRLAVAHALEKQRLDQIER 176
+ +E + Q + +Q +E+EL++ W E E+ RR A R Q+
Sbjct: 396 RRQEEQSLRQDQERRQRQERERELEEQARRQQQWQAEEESERRRQRLSARPSLRERQLRA 455
Query: 177 EERRFKMQEYMQQMDDVKKMREIDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXYDEK 356
EER+ + Q + ++ + ++ R+ +L+ E++E+++ +++
Sbjct: 456 EERQEQEQRFREEEEQRRERRQ--ELQFLEEEEQLQ------RRERAQQLQEEDSFQEDR 507
Query: 357 QNNLENIKNKLSAQLKLKMDDEDLRIRNAI----AEKEEKFQNDETDKEKKRQ------- 503
+ + + + ++ +E R R+ + ++E+ + +E +EK+RQ
Sbjct: 508 ERRRRQQEQRPGQTWRWQLQEEAQRRRHTLYAKPGQQEQLREEEELQREKRRQEREREYR 567
Query: 504 --DTLKSIEDHRKNTMKALEEDQRLNKQRDLDSLLARK--EADAILKENEDRRQKMRLTE 671
+ L+ ED ++ + + + L + R + L RK E + +L+E E+ R + + E
Sbjct: 568 EEEKLQREEDEKRRRQERERQYRELEELRQEEQLRDRKLREEEQLLQEREEERLRRQERE 627
Query: 672 AKKLAEEHLATAKAIKDSDENSMMNKLKIMEENQKLLDLEESVFQEYARKVIE 830
K EE L ++ E + K+ EE Q L E+ + QE RK+ E
Sbjct: 628 RKLREEEQLLR----QEEQELRQERERKLREEEQLLRREEQELRQERERKLRE 676
Score = 56.6 bits (135), Expect = 9e-08
Identities = 73/324 (22%), Positives = 144/324 (44%), Gaps = 49/324 (15%)
Frame = +3
Query: 6 EKIRKSKENVEFVKA--QIKYNQQIKEKELKDWNV----EGENIRRLAVAHALEKQRLDQ 167
E+ RK +E + ++ + + +Q +E++L++ E + +RR E+++L Q
Sbjct: 907 ERDRKLREEEQLLQESEEERLRRQERERKLREEEQLLRREEQELRRERARKLREEEQLLQ 966
Query: 168 IEREER-----------------RFKMQEYMQQMDDVKKMREIDKLKNEEDDEEIRIFXX 296
EER R + QE Q+ D +K RE ++L E ++E +R
Sbjct: 967 EREEERLRRQERARKLREEEQLLRREEQELRQERD--RKFREEEQLLQEREEERLR-RQE 1023
Query: 297 XXXXXXXXXXXXXXXXYDEKQNNLENIKNKLSAQLKLKMDDEDLRIRNAIAEKEEKFQND 476
+E+ + K +L Q++ + +++ LR + E++ KF+ +
Sbjct: 1024 RDRKFREEERQLRRQELEEQFRQERDRKFRLEEQIRQEKEEKQLRRQ----ERDRKFREE 1079
Query: 477 ETDKEK-KRQDTLKSIEDHRKNTMKAL---EEDQRLNKQ------RDLDSLLAR------ 608
E + + +R+ L+ D + + L E++RL +Q R+ + LL R
Sbjct: 1080 EQQRRRQEREQQLRRERDRKFREEEQLLQEREEERLRRQERARKLREEEQLLRREEQLLR 1139
Query: 609 -------KEADAILKENEDRRQKMRLTEAKKLAEEHLATAKAIKDSDENSMMNK---LKI 758
+E + +L+E+E+ R + + E K EE L +++ +E + + K+
Sbjct: 1140 QERDRKFREEEQLLQESEEERLRRQERERKLREEEQL-----LQEREEERLRRQERARKL 1194
Query: 759 MEENQKLLDLEESVFQEYARKVIE 830
EE Q L E+ + QE ARK+ E
Sbjct: 1195 REEEQLLRQEEQELRQERARKLRE 1218
Score = 53.9 bits (128), Expect = 6e-07
Identities = 54/283 (19%), Positives = 124/283 (43%), Gaps = 12/283 (4%)
Frame = +3
Query: 6 EKIRKSKENVEFVKAQIKYNQQIKEKELKD-----WNVEGENIRRLAVAHALEKQRLDQI 170
E+ RK +E + ++ + + +Q ++++ ++ E E +RR L ++
Sbjct: 1119 ERARKLREEEQLLRREEQLLRQERDRKFREEEQLLQESEEERLRRQERERKLREEEQLLQ 1178
Query: 171 EREERRFKMQEYMQQMDDVKKMREIDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXYD 350
EREE R + QE +K+RE ++L +E+ E +
Sbjct: 1179 EREEERLRRQER------ARKLREEEQLLRQEEQE------LRQERARKLREEEQLLRQE 1226
Query: 351 EKQNNLENIKNKLSAQLKLKMDDEDLRI-RNAIAEKEEKFQNDETDKEKKRQDTLKSIED 527
E++ E + + L+ ++++LR R+ +EE+ + ++ +RQ+ + + +
Sbjct: 1227 EQELRQERDRKFREEEQLLRREEQELRRERDRKFREEEQLLQEREEERLRRQERARKLRE 1286
Query: 528 HRKNTMKALEEDQRLNKQRD----LDSLLARKEADAILKE--NEDRRQKMRLTEAKKLAE 689
+ + +E+QRL ++RD + AR+E L+ ++ Q+ R +K E
Sbjct: 1287 EEEQLLFEEQEEQRLRQERDRRYRAEEQFAREEKSRRLERELRQEEEQRRRRERERKFRE 1346
Query: 690 EHLATAKAIKDSDENSMMNKLKIMEENQKLLDLEESVFQEYAR 818
E L + ++ ++ + + E+Q + E +++AR
Sbjct: 1347 EQL---RRQQEEEQRRRQLRERQFREDQSRRQVLEPGTRQFAR 1386
Score = 48.5 bits (114), Expect = 2e-05
Identities = 56/290 (19%), Positives = 129/290 (44%), Gaps = 18/290 (6%)
Frame = +3
Query: 6 EKIRKSKENVEFVKAQIKYNQQIKEKELKDWNVEGENIRRLAVAHALEKQ-----RLDQI 170
E+ R+ +E + ++ + +++ +E+E E E +RR A L ++ R +Q+
Sbjct: 1080 EQQRRRQEREQQLRRE--RDRKFREEEQLLQEREEERLRRQERARKLREEEQLLRREEQL 1137
Query: 171 EREERRFKMQEYMQQMDDV-----------KKMREIDKLKNEEDDEEIRIFXXXXXXXXX 317
R+ER K +E Q + + +K+RE ++L E ++E +R
Sbjct: 1138 LRQERDRKFREEEQLLQESEEERLRRQERERKLREEEQLLQEREEERLR----RQERARK 1193
Query: 318 XXXXXXXXXYDEKQNNLENIKNKLSAQLKLKMDDEDLRIRNAIAEKEEKFQNDETDKEKK 497
+E++ E + + L+ ++++LR E++ KF+ +E ++
Sbjct: 1194 LREEEQLLRQEEQELRQERARKLREEEQLLRQEEQELR-----QERDRKFREEEQLLRRE 1248
Query: 498 RQDTLKSIEDHRKNTMKALE--EDQRLNKQRDLDSLLARKEADAILKENEDRRQKMRLTE 671
Q+ + + + + L+ E++RL +Q L R+E + +L E ++ ++ + +
Sbjct: 1249 EQELRRERDRKFREEEQLLQEREEERLRRQERARKL--REEEEQLLFEEQEEQRLRQERD 1306
Query: 672 AKKLAEEHLATAKAIKDSDENSMMNKLKIMEENQKLLDLEESVFQEYARK 821
+ AEE A ++ + +L+ EE ++ + E +E R+
Sbjct: 1307 RRYRAEEQFA-----REEKSRRLERELRQEEEQRRRRERERKFREEQLRR 1351
Score = 47.8 bits (112), Expect = 4e-05
Identities = 58/324 (17%), Positives = 141/324 (43%), Gaps = 41/324 (12%)
Frame = +3
Query: 6 EKIRKSKENVEFVKAQIKYNQQIKEKELKDWNVEGENIRRLAVAHALEKQRLDQIEREER 185
E+ R+ + Q + Q ++++ ++ E + +RR +QRL+Q ER E+
Sbjct: 222 EQQRRERREQHERALQEEEEQLLRQRRWREEpreQQQLRRELEEIREREQRLEQEERREQ 281
Query: 186 RFKMQEYMQQMD--DVKKMREIDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXYDEKQ 359
+ + ++ ++Q + + + RE+++++ E ++++
Sbjct: 282 QLRREQRLEQEERREQQLRRELEEIREREQ------------------------RLEQEE 317
Query: 360 NNLENIKNKLSAQLKLKMDDEDLRIRNAIAEKEEK----FQNDETDKEKKRQDTL----- 512
+ ++ + + +LK + E++R R E+EE+ + ++ ++R ++L
Sbjct: 318 RREQRLEQEERREQQLKRELEEIREREQRLEQEERREQLLAEEVREQARERGESLTRRWQ 377
Query: 513 ------------KSIEDHRKNTMKALEED----QRLNKQRDLDSLLARKEADAILKENED 644
K R+ ++L +D QR ++R+L+ R++ +E+E
Sbjct: 378 RQLESEAGARQSKVYSRPRRQEEQSLRQDQERRQRQERERELEEQARRQQQWQAEEESER 437
Query: 645 RRQKM----RLTEAKKLAEEHLATAKAIKDSDE--NSMMNKLKIMEENQKL--------L 782
RRQ++ L E + AEE + ++ +E +L+ +EE ++L L
Sbjct: 438 RRQRLSARPSLRERQLRAEERQEQEQRFREEEEQRRERRQELQFLEEEEQLQRRERAQQL 497
Query: 783 DLEESVFQEYARKVIEHCEKGGRT 854
E+S ++ R+ + ++ G+T
Sbjct: 498 QEEDSFQEDRERRRRQQEQRPGQT 521
Score = 44.7 bits (104), Expect = 3e-04
Identities = 48/277 (17%), Positives = 127/277 (45%), Gaps = 1/277 (0%)
Frame = +3
Query: 15 RKSKENVEFVKAQIKYNQQIKEKELKDWNVEGENIRRLAVAHALEKQRLDQIEREERRFK 194
R ++ +E +A+ + ++ K ++ +++ +E E +RR + R ++ +R ERR +
Sbjct: 173 RLQRQELEERRAEEEQLRRRKGRDAEEF-IEEEQLRRREQQELKRELREEEQQRRERREQ 231
Query: 195 MQEYMQQMDDVKKMREIDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXYDEKQNNLEN 374
+ +Q+ ++ + +R+ + EE E+ ++ +++ +
Sbjct: 232 HERALQE-EEEQLLRQ--RRWREEpreQQQLRRELEEIREREQRLEQEERREQQLRREQR 288
Query: 375 IKNKLSAQLKLKMDDEDLRIRNAIAEKEEKFQNDETDKEKKRQDTLKSIEDHRKNTMKAL 554
++ + + +L+ + E++R R E+EE+ + +E++ Q + +E+ R
Sbjct: 289 LEQEERREQQLRRELEEIREREQRLEQEERREQRLEQEERREQQLKRELEEIR------- 341
Query: 555 EEDQRLNKQRDLDSLLARKEADAILKENED-RRQKMRLTEAKKLAEEHLATAKAIKDSDE 731
E +QRL ++ + LLA + + + E R+ R E++ A + ++ + +E
Sbjct: 342 EREQRLEQEERREQLLAEEVREQARERGESLTRRWQRQLESEAGARQSKVYSRP-RRQEE 400
Query: 732 NSMMNKLKIMEENQKLLDLEESVFQEYARKVIEHCEK 842
S+ + + ++ +LEE ++ + E E+
Sbjct: 401 QSLRQDQERRQRQERERELEEQARRQQQWQAEEESER 437
>sp|P47460|HMW2_MYCGE Cytadherence high molecular weight protein 2 (Cytadherence accessory
protein 2)
Length = 1805
Score = 60.5 bits (145), Expect = 6e-09
Identities = 66/254 (25%), Positives = 114/254 (44%), Gaps = 25/254 (9%)
Frame = +3
Query: 147 EKQRLDQIER---EERRFKMQEYMQQMDDVKKMREI-DKLKNEEDDEEIRIFXXXXXXXX 314
+K+ LDQ+ + +ER +E+ + + V+K +EI K + +
Sbjct: 628 QKETLDQLTKSFEQERLINQREHKELVASVEKQKEILGKKLQDFSQTSLNASKNLAEREM 687
Query: 315 XXXXXXXXXXYDEKQ-----NNLENIKNKLSAQLKLKMDDEDLRIRNAIAEKEEKFQNDE 479
EKQ NN E I+ L AQL ++ E ++NA ++ F ND
Sbjct: 688 AIKFKEKEIEATEKQLLNDVNNAEVIQADL-AQLNQSLNQERSELQNA-KQRIADFHNDS 745
Query: 480 TDKE-------KKRQDTLKSIEDHRK-----NTMKALEEDQRLNKQRDLDSLLARK---E 614
K +KR L+++E ++K N E +LN+++ L +K E
Sbjct: 746 LKKLNEYELSLQKRLQELQTLEANQKQHSYQNQAYFEGELDKLNREKQAFLNLRKKQTME 805
Query: 615 ADAILKENEDRRQKMRLTEAKKLAEEH-LATAKAIKDSDENSMMNKLKIMEENQKLLDLE 791
DAI + D+ Q + + +A+ + H L A D+D+ S+ ++L ++E QKL+DLE
Sbjct: 806 VDAIKQRLSDKHQALNMQQAELDRKTHELNNAFLNHDADQKSLQDQLATVKETQKLIDLE 865
Query: 792 ESVFQEYARKVIEH 833
S E R+ E+
Sbjct: 866 RSALLEKQREFAEN 879
Score = 38.9 bits (89), Expect = 0.019
Identities = 49/234 (20%), Positives = 102/234 (43%), Gaps = 4/234 (1%)
Frame = +3
Query: 15 RKSKENVEFVKAQIKYNQQIKEKELKDWNVEGENIRRLAVAHALEKQRLDQIEREERRFK 194
RK+K N +F K + ++ + + LK LE Q+ Q + FK
Sbjct: 1373 RKTKLNNDFAKFS-RQREEFENQRLK----------------LLELQKTLQTQTNSNNFK 1415
Query: 195 MQEYMQQMDDVKK-MREIDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXYDEKQNNLE 371
+ + + K+ M E++ K E D + R++ K+ +
Sbjct: 1416 TKAIQEIENSYKRGMEELNFQKKEFDKNKSRLYEYFRKMRDEIERKESQVKLVLKETQRK 1475
Query: 372 -NIKNKLSAQLKLKMDDEDLRIRNAIAEKEEKFQN-DETDKEKKRQDTLKSIEDHRKNTM 545
N+ + +L ++ + D + + A K++ Q+ D T+K++K + L + +++
Sbjct: 1476 ANLLEAQANKLNIEKNTIDFKEKELKAFKDKVDQDIDSTNKQRKELNEL--LNENKLLQQ 1533
Query: 546 KALEEDQRLNKQRDLDSLLARKEADAILKENEDRRQK-MRLTEAKKLAEEHLAT 704
+E ++ +N + DSLL K+ + I ++ D+ + +RL + KLAE+ T
Sbjct: 1534 SLIERERAINSK---DSLL-NKKIETIKRQLHDKEMRVLRLVDRMKLAEQKYQT 1583
Score = 30.4 bits (67), Expect = 6.8
Identities = 49/241 (20%), Positives = 96/241 (39%), Gaps = 10/241 (4%)
Frame = +3
Query: 6 EKIRKSKENVEFVKA----QIKYNQQIKEKELKDWNVEGENIRRLAVAHALEKQRLDQIE 173
EK R+ ENV K + Q+I E K + + + L +A + ++
Sbjct: 871 EKQREFAENVAGFKRHWSNKTSQLQKIYELTKKQESEQTQKETELKIAFS-------DLQ 923
Query: 174 REERRFKMQEYMQQMDDVKKMREIDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXYDE 353
++ + F++Q+ + K RE+DKL + + ++ + D
Sbjct: 924 KDYQVFELQKDQEFRQIEAKQRELDKLAEKNNQVKLEL--------------------DN 963
Query: 354 KQNNLENIK-NKLSAQLKLKMDDEDLRIRNAIAEKEEKFQNDETDKEKKRQDTLKSI--- 521
+ L+N K + + AQL+L+ + L + ++ F K+R+ K I
Sbjct: 964 RFQALQNQKQDTVQAQLELEREQHQLNL------EQTAFNQANESLLKQREQLTKKIQAF 1017
Query: 522 --EDHRKNTMKALEEDQRLNKQRDLDSLLARKEADAILKENEDRRQKMRLTEAKKLAEEH 695
E ++N AL+ + K++D RK+ + + + ++ EAKK E
Sbjct: 1018 HYELKKRNQFLALKGKRLFAKEQDQQ----RKDQEINWRFKQFEKEYTDFDEAKKRELEE 1073
Query: 696 L 698
L
Sbjct: 1074 L 1074
>sp|P08799|MYS2_DICDI Myosin II heavy chain, non muscle
Length = 2116
Score = 58.2 bits (139), Expect = 3e-08
Identities = 66/298 (22%), Positives = 129/298 (43%), Gaps = 20/298 (6%)
Frame = +3
Query: 6 EKIRKSKENVEFVKAQIK-YNQQIKEKELKDWNVEGENIRRLAVAHALEKQRLDQIEREE 182
E +K ++V+ +K Q++ +++ E E +E EN LA A K R + E++
Sbjct: 1755 EAKKKLTDDVDTLKKQLEDEKKKLNESERAKKRLESENEDFLAKLDAEVKNR-SRAEKDR 1813
Query: 183 RRFK--MQEYMQQMDD---VKKMREIDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXY 347
++++ +++ +++D K EI K E+ +E+R
Sbjct: 1814 KKYEKDLKDTKYKLNDEAATKTQTEIGAAKLEDQIDELR--------SKLEQEQAKATQA 1865
Query: 348 DEKQNNLENIKNKLSAQL------KLKMDDEDLRIRNAIAEKEEKFQNDETDKEKKRQDT 509
D+ + LE + L AQ+ K++++ E + + E E + E K + Q
Sbjct: 1866 DKSKKTLEGEIDNLRAQIEDEGKIKMRLEKEKRALEGELEELRETVEEAEDSKSEAEQSK 1925
Query: 510 LK---SIEDHRKNTMKALE-----EDQRLNKQRDLDSLLARKEADAILKENEDRRQKMRL 665
+ED R+N K ++ ED + N QR++ R E ++I + N DR +K
Sbjct: 1926 RLVELELEDARRNLQKEIDAKEIAEDAKSNLQREIVEAKGRLEEESIARTNSDRSRKRLE 1985
Query: 666 TEAKKLAEEHLATAKAIKDSDENSMMNKLKIMEENQKLLDLEESVFQEYARKVIEHCE 839
E L + A KA + + + ++ E +K + E++ +E+ V+E E
Sbjct: 1986 AEIDALTAQVDAEQKAKNQQIKENKKIETELKEYRKKFGESEKTKTKEFL--VVEKLE 2041
Score = 39.3 bits (90), Expect = 0.015
Identities = 60/283 (21%), Positives = 128/283 (45%), Gaps = 14/283 (4%)
Frame = +3
Query: 18 KSKENVEFVKAQIKYNQQ-IKEKELKDWNVEGENIRRLAVAHALEKQRLDQIEREERRFK 194
K + ++E ++ QI Q I + E +EGE + RL E+ +E+++++ +
Sbjct: 1147 KQESDMEALRNQISELQSTIAKLEKIKSTLEGE-VARLQGELEAEQLAKSNVEKQKKKVE 1205
Query: 195 MQ---EYMQQMDDVKKMREIDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXYDEKQNN 365
+ + Q ++ + +DKLK + + E + + E N
Sbjct: 1206 LDLEDKSAQLAEETAAKQALDKLKKKLEQELSEVQTQLSEANNKNVNSDSTNKHLETSFN 1265
Query: 366 LENIKNKLSAQLKLKMDDEDLRIRNAIAEKEEKFQNDETDKEKKRQDTLKSIEDHRKNTM 545
N+K +L A+ K K E R+ E E K N++ ++EKK++++ + + + +
Sbjct: 1266 --NLKLELEAEQKAKQALEKKRLG---LESELKHVNEQLEEEKKQKESNEKRKVDLEKEV 1320
Query: 546 KALEE--DQRLNKQRDLDSLLARKEADAILKENEDRRQKMRLTEAKKLAEEHLATAKAIK 719
L++ ++ + ++ + +KE++ +E +RQ + ++ + E L T +A
Sbjct: 1321 SELKDQIEEEVASKKAVTEAKNKKESEL----DEIKRQYADVVSSRDKSVEQLKTLQAKN 1376
Query: 720 DSDENS---MMNKLKIMEENQKL--LDLEESV---FQEYARKV 824
+ N+ +L E ++K DLEE+V +E A+KV
Sbjct: 1377 EELRNTAEEAEGQLDRAERSKKKAEFDLEEAVKNLEEETAKKV 1419
Score = 37.0 bits (84), Expect = 0.072
Identities = 54/264 (20%), Positives = 111/264 (42%), Gaps = 6/264 (2%)
Frame = +3
Query: 21 SKENVEFVKAQIKYNQQIKEKELKDWNVEGENIRRLAVAHALEKQRLDQIEREERRFKMQ 200
SK+ +E K +++ + E EL + + EN++ +K+ +++ R+ ++
Sbjct: 885 SKDALEAQKRELEIRVEDMESELDEKKLALENLQN-------QKRSVEEKVRD-----LE 932
Query: 201 EYMQQMDDVKKMREIDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXYDEKQNNLENIK 380
E +Q+ ++ E K K EE+ EE++ DE Q +E +
Sbjct: 933 EELQEEQKLRNTLEKLKKKYEEELEEMK----RVNDGQSDTISRLEKIKDELQKEVEELT 988
Query: 381 NKLSAQLKLK--MDDEDLRIRNAIAEKEEKFQNDETDK-EKKRQDTLKSIEDHRKNTMKA 551
S + K K ++ +R+++ + + + ++ DK E RQ K +E+ K +A
Sbjct: 989 ESFSEESKDKGVLEKTRVRLQSELDDLTVRLDSETKDKSELLRQK--KKLEEELKQVQEA 1046
Query: 552 LEEDQRLN-KQRDLDSLLARKEADAILKENEDRRQKMRLTEAKKLAEEHLATAKAIKDSD 728
L + Q + L + + K N + + + ++KK E L D +
Sbjct: 1047 LAAETAAKLAQEAANKKLQGEYTELNEKFNSEVTARSNVEKSKKTLESQLVAVNNELDEE 1106
Query: 729 ENSMMNKLKIMEENQKLLD--LEE 794
+ + +E+ +K LD LEE
Sbjct: 1107 KKNR----DALEKKKKALDAMLEE 1126
Score = 33.5 bits (75), Expect = 0.80
Identities = 61/289 (21%), Positives = 120/289 (41%), Gaps = 23/289 (7%)
Frame = +3
Query: 6 EKIRKSKENVEFVKAQ--------IKYNQQIKE--KELKDWNVEGENIRRLAVAHALEKQ 155
E IRK ++ ++A+ IK ++ K K+ D + E +R V K+
Sbjct: 1533 EFIRKKDAEIDDLRARLDRETESRIKSDEDKKNTRKQFADLEAKVEEAQREVVTIDRLKK 1592
Query: 156 RLD--------QIEREER-RFKMQEYMQQMDD-VKKMREIDKLKNEEDDEEIRIFXXXXX 305
+L+ Q++ E + R K+++ ++++ + + R ++ ++ DEEIR
Sbjct: 1593 KLESDIIDLSTQLDTETKSRIKIEKSKKKLEQTLAERRAAEEGSSKAADEEIR------- 1645
Query: 306 XXXXXXXXXXXXXYDEKQNNLENIKNKLSAQLKLKMDDEDLRIRNAIAEKEEKFQN--DE 479
DE + L++ + L+A K +I++ +AE +E + DE
Sbjct: 1646 -------KQVWQEVDELRAQLDSERAALNASEK--------KIKSLVAEVDEVKEQLEDE 1690
Query: 480 TDKEKKRQDTLKSIEDHRKNTMKALEEDQRLNKQ-RDLDSLLARKEADAILKENEDRRQK 656
+ K +++E + LEE++ + D L + D K + + Q
Sbjct: 1691 ILAKDKLVKAKRALEVELEEVRDQLEEEEDSRSELEDSKRRLTTEVEDIKKKYDAEVEQN 1750
Query: 657 MRLTEAKKLAEEHLATAKAIKDSDENSMMNKLKIMEENQKLLDLEESVF 803
+L EAKK + + T K + ++ KL E +K L+ E F
Sbjct: 1751 TKLDEAKKKLTDDVDTLKKQLEDEK----KKLNESERAKKRLESENEDF 1795
>sp|P22793|TRHY_SHEEP Trichohyalin
Length = 1549
Score = 57.8 bits (138), Expect = 4e-08
Identities = 62/286 (21%), Positives = 131/286 (45%), Gaps = 17/286 (5%)
Frame = +3
Query: 6 EKIRKSKENVEFVKAQIKYNQQIKEKELKDWNVEGENIRRLAVAHALEKQRLDQIEREER 185
E+ RK +E + ++ + K +Q +E +L+ E R+ L ++R +Q+ R+ER
Sbjct: 1196 ERDRKFREEEQLLQEREKLRRQEREPQLRQ-----ERDRKFHEEEQLLQEREEQLRRQER 1250
Query: 186 RFKMQEYMQQMDDVKKMREIDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXYDEKQNN 365
K +E Q + + RE ++L+ +E D + R E++
Sbjct: 1251 DRKFREEAQLLQE----RE-EQLRRQERDRKFR----------------------EEEQL 1283
Query: 366 LENIKNKLSAQLKLKMDDEDLRIRNAIAEKEEKFQNDETDKE-KKRQDTLKSIED----- 527
L+ + +L Q + + E+ ++ + E+EE+ + E D++ ++ + LK E+
Sbjct: 1284 LQEREEQLRRQERDRKFREEEQL---LQEREEQLRRQERDRKFREEEQLLKESEEQLRRQ 1340
Query: 528 ------HRKNTMKALEEDQRLNKQRDLDSLLARKE-ADAILKENEDRRQKMR----LTEA 674
H K + E+Q+L +Q +L+ + +++E +E E RRQ+ R L E
Sbjct: 1341 ERDRKFHEKEHLLREREEQQLRRQ-ELEGVFSQEEQLRRAEQEEEQRRQRQRDRKFLEEE 1399
Query: 675 KKLAEEHLATAKAIKDSDENSMMNKLKIMEENQKLLDLEESVFQEY 812
+ L E + +++ D + + ++ E Q+ L + + Q+Y
Sbjct: 1400 QSLQREREEEKRRVQEQDRKFLEQEEQLHREEQEELRRRQQLDQQY 1445
Score = 53.9 bits (128), Expect = 6e-07
Identities = 57/278 (20%), Positives = 121/278 (43%), Gaps = 20/278 (7%)
Frame = +3
Query: 66 QQIKEKELKDWNVEGENIRRLAVAHALEKQRLDQIEREERRFKMQEYMQQMDDVKKMREI 245
Q+ K + ++W + + LE+++ + ER +R+F+ +E + + +K+R +
Sbjct: 900 QEEKREREQEWRSRQKRDSQFPAEQLLEREQQKETERRDRKFREEEQLLKGQREEKIRYL 959
Query: 246 DK-LKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXYDEKQNNLENIKNKLSAQLKLKMDDE 422
++ K E+++++R E++ L +++ + +L +
Sbjct: 960 EEDRKFREEEQQLRRL--------------------EREQQLRQERDRKFRE-ELSRQER 998
Query: 423 DLRIR---NAIAEKEEKFQNDETDKEKKRQDTLKSIEDHRKNTMKALEEDQRLNKQRDL- 590
D + R + E+EE+ + E D++ + ++ L R+ ++ E D++ ++ L
Sbjct: 999 DRKFREEEQLLQEREEQLRRQERDRKFREEEQLL---QEREEQLRRQERDRKFREEEQLL 1055
Query: 591 ---DSLLARKEADAILKENE------DRRQKMRLTEAKKLAEEHLATAKAIK---DSDEN 734
+ L R+E D +E E +R Q++R +K EE L + + E
Sbjct: 1056 QEREEQLRRQERDRKFREEEQQLRLLEREQQLRQERNRKFREEQLLREREEQLRLQEGEP 1115
Query: 735 SMMNK--LKIMEENQKLLDLEESV-FQEYARKVIEHCE 839
+ K K EE Q L + EE + QE RK E +
Sbjct: 1116 QLRQKRDRKFHEEEQLLQEREEQLRRQERDRKFREEAQ 1153
Score = 49.3 bits (116), Expect = 1e-05
Identities = 63/299 (21%), Positives = 124/299 (41%), Gaps = 41/299 (13%)
Frame = +3
Query: 69 QIKEKELKDWNVEGENIRRLAVAHALEKQRLDQIEREERRFKMQE---YMQQMDDVKKMR 239
Q +E++L+ E R+ + K+R +Q+ R+ER K +E +Q+ +++++
Sbjct: 1133 QEREEQLR----RQERDRKFREEAQILKEREEQLRRQERDRKFREEEQLLQEREELRRQE 1188
Query: 240 EIDKLKNEED---DEEIRIFXXXXXXXXXXXXXXXXXXYDEKQNNLENIKNKLSAQLKLK 410
+L+ E D EE ++ D K + E + + QL+ +
Sbjct: 1189 REPQLRQERDRKFREEEQLLQEREKLRRQEREPQLRQERDRKFHEEEQLLQEREEQLRRQ 1248
Query: 411 MDDEDLRIR-NAIAEKEEKFQNDETDKE--------KKRQDTLKSIEDHRK--------- 536
D R + E+EE+ + E D++ ++R++ L+ E RK
Sbjct: 1249 ERDRKFREEAQLLQEREEQLRRQERDRKFREEEQLLQEREEQLRRQERDRKFREEEQLLQ 1308
Query: 537 ---NTMKALEEDQRLNKQRDL----DSLLARKEADA-------ILKENEDRRQKMRLTEA 674
++ E D++ ++ L + L R+E D +L+E E+++ + + E
Sbjct: 1309 EREEQLRRQERDRKFREEEQLLKESEEQLRRQERDRKFHEKEHLLREREEQQLRRQELEG 1368
Query: 675 KKLAEEHLATAKAIKDSDENSMMNKLKIMEENQKL---LDLEESVFQEYARKVIEHCEK 842
EE L A+ ++ K +EE Q L + E+ QE RK +E E+
Sbjct: 1369 VFSQEEQLRRAEQ-EEEQRRQRQRDRKFLEEEQSLQREREEEKRRVQEQDRKFLEQEEQ 1426
Score = 47.4 bits (111), Expect = 5e-05
Identities = 57/284 (20%), Positives = 122/284 (42%), Gaps = 12/284 (4%)
Frame = +3
Query: 6 EKIRKSKENVEFVKAQIKYNQQIKEKELKDWNVEGENIRRLAVAHA--LEKQRL---DQI 170
EK R+ +E ++ + +++ ++ ++E + E RR LEK L +Q+
Sbjct: 406 EKRRQERER-QYREVELQREEERLQREEEQLQREEREKRRRQEREKQYLEKVELWEEEQL 464
Query: 171 EREERRFKMQEYMQQMDDVKKMREIDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXYD 350
+REER + QE +Q + ++RE ++L+ +E ++ Y
Sbjct: 465 QREEREKRRQEREKQYLEKVELREEEQLQRQEREKR---------------RQERERQYL 509
Query: 351 EKQNNLENIKNKLSAQLKLKMDDEDLRIRNAIAEKEEKFQNDETDKEKKRQDT--LKSIE 524
EK E + + + K + + E + ++EE+ Q E +K ++ ++ L+ +E
Sbjct: 510 EKVELQEEEQLQREEREKRRQERERQYLEKVELQEEEQLQRQEREKRRQEREKQYLEKVE 569
Query: 525 DHRKNTMKALEEDQRLNKQRD--LDSLLARKEADAILKENEDRRQ---KMRLTEAKKLAE 689
+ ++ E +R ++ L+ + ++E +E E RRQ + L + + E
Sbjct: 570 LQEEEQLQRQERQKRRQEREKQYLEKVELQEEEQLQRQEREKRRQERERQYLEKVELQEE 629
Query: 690 EHLATAKAIKDSDENSMMNKLKIMEENQKLLDLEESVFQEYARK 821
E + + K E K ++ ++ L EE + +E K
Sbjct: 630 EQVQRQEREKRRQERERQYLEKELQRQEERLQEEEQLLREEREK 673
Score = 47.4 bits (111), Expect = 5e-05
Identities = 60/295 (20%), Positives = 130/295 (44%), Gaps = 16/295 (5%)
Frame = +3
Query: 6 EKIRKSKENVEFVKAQIKYNQQIKEKELKDWNVEGENIRRLAVAHALEKQRL---DQIER 176
EK R+ +E K +++ +Q++ +E + E E + L +++RL +Q+ R
Sbjct: 610 EKRRQERERQYLEKVELQEEEQVQRQEREKRRQERER-QYLEKELQRQEERLQEEEQLLR 668
Query: 177 EERRFKMQEYMQQMDDVKKMREIDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXYDEK 356
EER + QE +Q + +++E ++L+ EE E+ R EK
Sbjct: 669 EEREKRRQERERQYLEKVELQEEEQLQREE-REKRRQERERQYLEKEELQRQEERLQREK 727
Query: 357 QNNLENIKNKLSAQLKLKMDDEDLRIRNAIAEKEEKFQNDETDKEKKRQDTLKSIEDHRK 536
+ + K + K +E+L+ ++E++ ++ +K + + E+ +
Sbjct: 728 EQLQREDREKRRQVRERKYLEEELQQEEDRLQREKQLLREDREKRQYLEKVELQREEEQL 787
Query: 537 NTMKALEEDQRLNKQRDL---DSLLARKEADAILKENEDRRQKMRLTEAKKLAEEHLATA 707
K +E +R ++ +L + L RKE +E E RR++ + ++ + L
Sbjct: 788 QREKRRQERERQYREEELLREEERLHRKEQQLQREECEKRRRQELERQLEEEELQRLDRK 847
Query: 708 KAIKDSDENS-------MMNKLKIMEENQKLLD---LEESVFQEYARKVIEHCEK 842
+ +D D++ + +K + +E + LD + ES FQ+ R + + E+
Sbjct: 848 RQFRDDDQHQNEVRNSRVYSKHRENKEKSRQLDDSWVRESQFQQDLRPLQDEQEE 902
Score = 42.4 bits (98), Expect = 0.002
Identities = 52/251 (20%), Positives = 109/251 (43%), Gaps = 20/251 (7%)
Frame = +3
Query: 6 EKIRKSKENVEFVKAQIKYNQQIKEKELKDWNVEGENIRRLAVAHALEKQRLDQIEREER 185
E+ RK +E + + Q +E++L+ E R+ L ++R +Q+ R+ER
Sbjct: 1249 ERDRKFREEAQLL--------QEREEQLR----RQERDRKFREEEQLLQEREEQLRRQER 1296
Query: 186 RFKMQE---YMQQMDDVKKMREIDKLKNEED------DEEIRIFXXXXXXXXXXXXXXXX 338
K +E +Q+ ++ + +E D+ EE+ +E++R
Sbjct: 1297 DRKFREEEQLLQEREEQLRRQERDRKFREEEQLLKESEEQLRRQERDRKFHEKEHLLRER 1356
Query: 339 XXYDEKQNNLENIKNKLSAQLKLKMDDEDLRIRNA---IAEKEEKFQNDETDKEKKRQDT 509
++ LE + ++ + + ++E R R E+E+ Q + +++++ Q+
Sbjct: 1357 EEQQLRRQELEGVFSQEEQLRRAEQEEEQRRQRQRDRKFLEEEQSLQREREEEKRRVQEQ 1416
Query: 510 ----LKSIEDHRKNTMKALEEDQRLNKQRDLDSLLARKEA----DAILKENEDRRQKMRL 665
L+ E + + L Q+L++Q + AR+E + L++ E RR++ R
Sbjct: 1417 DRKFLEQEEQLHREEQEELRRRQQLDQQYRAEEQFAREEKRRRQEQELRQEEQRRRQER- 1475
Query: 666 TEAKKLAEEHL 698
E K EE L
Sbjct: 1476 -ERKFREEEQL 1485
Score = 41.2 bits (95), Expect = 0.004
Identities = 63/291 (21%), Positives = 124/291 (42%), Gaps = 31/291 (10%)
Frame = +3
Query: 51 QIKYNQQIKEKELKDWNVEGE------NIRRLAVAHALEKQRLDQIEREERRFKMQEYMQ 212
+ + Q ++E+E + EGE R+ L ++R +Q+ R+ER K +E Q
Sbjct: 1094 KFREEQLLREREEQLRLQEGEPQLRQKRDRKFHEEEQLLQEREEQLRRQERDRKFREEAQ 1153
Query: 213 QMDDVKKMREIDKLKNEEDD----EEIRIFXXXXXXXXXXXXXXXXXXYDEKQNNLENI- 377
+ K RE ++L+ +E D EE ++ D K E +
Sbjct: 1154 ----ILKERE-EQLRRQERDRKFREEEQLLQEREELRRQEREPQLRQERDRKFREEEQLL 1208
Query: 378 -------KNKLSAQLKLKMDDEDLRIRNAIAEKEEKFQNDETDKEKKRQDTLKSIEDHRK 536
+ + QL+ + D + + E+EE+ + E D++ + + L R+
Sbjct: 1209 QEREKLRRQEREPQLRQERDRKFHEEEQLLQEREEQLRRQERDRKFREEAQLL---QERE 1265
Query: 537 NTMKALEEDQRLNKQRDL----DSLLARKEADAILKENE----DRRQKMRLTEA-KKLAE 689
++ E D++ ++ L + L R+E D +E E +R +++R E +K E
Sbjct: 1266 EQLRRQERDRKFREEEQLLQEREEQLRRQERDRKFREEEQLLQEREEQLRRQERDRKFRE 1325
Query: 690 EHLATAKAIKDSDENSMMNKLKIMEENQKLLD----LEESVFQEYARKVIE 830
E + +K+S+E +L+ E ++K + L E Q+ R+ +E
Sbjct: 1326 EE----QLLKESEE-----QLRRQERDRKFHEKEHLLREREEQQLRRQELE 1367
Score = 38.1 bits (87), Expect = 0.033
Identities = 54/277 (19%), Positives = 121/277 (43%), Gaps = 9/277 (3%)
Frame = +3
Query: 18 KSKENVEFVKAQIKYNQQIKEKELKDWNVEGENIRRLAVAHALEKQRLDQIEREERRFKM 197
K +E E + + ++ +Q +++E + VE + +R + E+ +L + E +E + +
Sbjct: 176 KGRELEELLNREQRFERQ-EQRERQRLQVEQQQRQRGELRERQEEVQLQKRETQELQRER 234
Query: 198 QEYMQQMDDVKKMREIDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXYDEKQNNLENI 377
E QQ+ K+ E L+ E ++E+R +E E+
Sbjct: 235 LEEEQQLQKQKRGLEERLLEQERREQELR-RKEQERREQQLRQEQEEATQEEISERGESR 293
Query: 378 KNKLSAQLKLKMDDEDLRIRNAIAEKEEKFQNDETDKEKKRQDTLKSIEDHRKNTMKALE 557
++ QL+ + D ++ + +E++ + E + +++Q+ S E +++L+
Sbjct: 294 TSRCQWQLESEADARQRKVYSRPHRQEQQSRRQEQELLERQQEQQISEE------VQSLQ 347
Query: 558 ED---QRLNKQRDLDS---LLARKEADA---ILKENEDRRQKMRLTEAKKLAEEHLATAK 710
ED QRL +++ D +E+ L +R+++R E +L EE L K
Sbjct: 348 EDQGRQRLKQEQRYDQNWRWQLEEESQRRRYTLYAKPAQREQVREEEQLRLKEEKLQREK 407
Query: 711 AIKDSDENSMMNKLKIMEENQKLLDLEESVFQEYARK 821
+ + ++++ E ++L EE + +E K
Sbjct: 408 --RRQERERQYREVELQREEERLQREEEQLQREEREK 442
Score = 32.7 bits (73), Expect = 1.4
Identities = 39/204 (19%), Positives = 88/204 (43%), Gaps = 17/204 (8%)
Frame = +3
Query: 6 EKIRKSKENVEFVKAQIKYNQQIKEKELKDWNVEGENIRRLAVAHALEKQRLDQIEREER 185
E+ RK +E + +K +Q++ +E E E++ R L +Q L+ + +E
Sbjct: 1318 ERDRKFREEEQLLKES---EEQLRRQERDRKFHEKEHLLREREEQQLRRQELEGVFSQEE 1374
Query: 186 RFKMQEY-----MQQMDDVKKMREIDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXYD 350
+ + E Q+ D K + E L+ E ++E+ R+ +
Sbjct: 1375 QLRRAEQEEEQRRQRQRDRKFLEEEQSLQREREEEKRRV-----QEQDRKFLEQEEQLHR 1429
Query: 351 EKQNNLEN---------IKNKLSAQLKLKMDDEDLRI--RNAIAEKEEKFQNDETDKEKK 497
E+Q L + + + + K + +++LR + E+E KF+ +E + ++
Sbjct: 1430 EEQEELRRRQQLDQQYRAEEQFAREEKRRRQEQELRQEEQRRRQERERKFREEEQLRRQQ 1489
Query: 498 RQDTLKSIE-DHRKNTMKALEEDQ 566
+++ + E D +++ + EED+
Sbjct: 1490 QEEQKRRQERDVQQSRRQVWEEDK 1513
>sp|P46504|YLX8_CAEEL Hypothetical protein F23F12.8 in chromosome III precursor
Length = 887
Score = 55.8 bits (133), Expect = 2e-07
Identities = 50/263 (19%), Positives = 118/263 (44%), Gaps = 32/263 (12%)
Frame = +3
Query: 138 HALEKQRLDQIEREERRF-KMQEYMQQMDDVKKMREIDKLKNEEDDEEIR---------I 287
H ++ Q+ +++ +F KM++ + + +K RE+++ + E+ E R I
Sbjct: 300 HIVQHQKTVSERQQQEKFEKMEQERLRQEKEEKARELERRRKLEESETARQAELDRQATI 359
Query: 288 FXXXXXXXXXXXXXXXXXXYDEKQNNLENIKNKLSA----------QLKLKMDDEDLRIR 437
+ +EK+ E ++ + A +L+L+ ++ R+R
Sbjct: 360 YAEQERMAMERNRELERIRLEEKKRENERVRQEEIAMEISKIRELERLQLERQRKNERVR 419
Query: 438 NAI-AEKEEKFQNDETDK----EKKRQDTLKSIEDHRKNTMKALEEDQRLNKQRDLDSLL 602
+ A ++ K Q +E + +K + ++ E+ R+ ++ LEE++ +R L
Sbjct: 420 QELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLRVLEEERARELERVRQEEL 479
Query: 603 ARKEADAILKENEDRRQKMRLTEAKKLAEEHLATAKAIKDSDENSMMNKLKIMEENQK-- 776
R+ IL++ E+ ++K +L + ++ E+ A ++ NK K++EE K
Sbjct: 480 ERQHQMEILRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMKENKQKMIEEKNKRK 539
Query: 777 -----LLDLEESVFQEYARKVIE 830
+ D + ++++E R++ E
Sbjct: 540 MLEKEMEDRQNAIYEEEERRIAE 562
Score = 51.2 bits (121), Expect = 4e-06
Identities = 62/289 (21%), Positives = 131/289 (45%), Gaps = 25/289 (8%)
Frame = +3
Query: 3 AEKIRKSKENVEFVKAQIKYNQQIKEKELKDWNVEGENIRRLAVAHA-----------LE 149
AE R++ E + ++ N++++ L++ E E +R+ +A LE
Sbjct: 351 AELDRQATIYAEQERMAMERNRELERIRLEEKKRENERVRQEEIAMEISKIRELERLQLE 410
Query: 150 KQRLDQIEREE----RRFKMQEYMQQMDDVKKMREIDKLKNEED--DEEIRIFXXXXXXX 311
+QR ++ R+E R++K+QE +Q ++ E+++++ +E+ E++R+
Sbjct: 411 RQRKNERVRQELEAARKYKLQEEERQRKIQQQKVEMEQIRQQEEARQEQLRVLEEERARE 470
Query: 312 XXXXXXXXXXXYDEKQNNLENIKNKLSAQLKLKMD--------DEDLRIRNAIAEKEEKF 467
E+Q+ +E ++ + Q K K++ E + I EKE K
Sbjct: 471 LERVRQEEL----ERQHQMEILRQQEEDQKKKKLEKDREQREQQEAEELNRMIIEKEMKE 526
Query: 468 QNDETDKEKKRQDTLKSIEDHRKNTMKALEEDQRLNKQRDLDSLLARKEADAILKENEDR 647
+ +EK ++ L+ + R+N + EE + ++R RK+ E E+R
Sbjct: 527 NKQKMIEEKNKRKMLEKEMEDRQNAIYEEEERRIAEEER-------RKQI-----EIEER 574
Query: 648 RQKMRLTEAKKLAEEHLATAKAIKDSDENSMMNKLKIMEENQKLLDLEE 794
R R+ + +A E + A++ E M+ ++K E+ +K L+ +E
Sbjct: 575 R---RIQQQIMIATEERSRLDAME--REREMLRQIKESEKQRKELERQE 618
>sp|Q07283|TRHY_HUMAN Trichohyalin
Length = 1898
Score = 54.7 bits (130), Expect = 3e-07
Identities = 64/295 (21%), Positives = 124/295 (42%), Gaps = 20/295 (6%)
Frame = +3
Query: 6 EKIRKSKENVEFVKAQIKYNQQIKEKELK-DWNVEGENIRRLAVAHALEKQRLDQIEREE 182
E+ + +E ++ K + +Y + + +LK W E EN A+ ++ RE
Sbjct: 1154 ERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKEN--------AVRDNKVYCKGREN 1205
Query: 183 RRFKMQEYMQQMDDVKKMREIDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXYDEKQN 362
+F+ E Q+ D + +++ L E+ + + + ++
Sbjct: 1206 EQFRQLED-SQVRDRQSQQDLQHLLGEQQERD---------REQERRRWQQANRHFPEEE 1255
Query: 363 NLENIKNKLSAQLKLKMDDEDLRIRNAIAEKEEKFQNDETDK----------EKKRQDTL 512
LE + K + + K +E +R E+EEK + ETD+ E++ Q L
Sbjct: 1256 QLEREEQKEAKRRDRKSQEEKQLLRE---EREEKRRRQETDRKFREEEQLLQEREEQPLL 1312
Query: 513 KSIED---------HRKNTMKALEEDQRLNKQRDLDSLLARKEADAILKENEDRRQKMRL 665
+ D H++ K LEE+QRL ++R+ L ++E L+E R+++R
Sbjct: 1313 RQERDRKFREEELLHQEQGRKFLEEEQRLREERERKFL--KEEQQLRLEE----REQLRQ 1366
Query: 666 TEAKKLAEEHLATAKAIKDSDENSMMNKLKIMEENQKLLDLEESVFQEYARKVIE 830
+K EE ++ +D +++ E +K L+ E+ + QE RK E
Sbjct: 1367 DRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFRE 1421
Score = 49.3 bits (116), Expect = 1e-05
Identities = 52/261 (19%), Positives = 117/261 (44%), Gaps = 8/261 (3%)
Frame = +3
Query: 15 RKSKENVEFVKAQIKYNQQIKEKELKDWNVEGENIRRLAVAHALEKQRLDQIEREERRFK 194
R+ + E +A+ + Q K E +++ E E +RR + LE +R + E++++R +
Sbjct: 177 RQEWQEREERRAEEEQLQSCKGHETEEFPDE-EQLRRREL---LELRRKGREEKQQQRRE 232
Query: 195 MQEYMQQMDDVKKMR--------EIDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXYD 350
Q+ + Q ++ K+ R E +KL+ EE + + +
Sbjct: 233 RQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQE 292
Query: 351 EKQNNLENIKNKLSAQLKLKMDDEDLRIRNAIAEKEEKFQNDETDKEKKRQDTLKSIEDH 530
E+Q + +L + +L+ E+ R R E+ E+ + E +E++ Q + E+
Sbjct: 293 EEQQ-----QQRLRREQQLRRKQEEER-REQQEERREQQERREQQEERREQQLRREQEER 346
Query: 531 RKNTMKALEEDQRLNKQRDLDSLLARKEADAILKENEDRRQKMRLTEAKKLAEEHLATAK 710
R+ ++ +E++R +Q + R+E ++ E+RR++ E + E+ L +
Sbjct: 347 REQQLRREQEEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQ 406
Query: 711 AIKDSDENSMMNKLKIMEENQ 773
++ E + + ++ E Q
Sbjct: 407 QLR--REQQLRREQQLRREQQ 425
Score = 48.9 bits (115), Expect = 2e-05
Identities = 55/294 (18%), Positives = 133/294 (45%), Gaps = 6/294 (2%)
Frame = +3
Query: 6 EKIRKSKENVEFVKAQIKYNQQIK-EKELKDWNVEGENIRRLAVAHALEKQRLDQIEREE 182
+++R+ +E E + Q++ QQ++ E++L+ + +RR ++ R +Q R E
Sbjct: 375 QQLRREQEE-ERREQQLRREQQLRREQQLR----REQQLRREQQLRREQQLRREQQLRRE 429
Query: 183 RRFKMQEYMQQMDDVKKMREIDK--LKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXYDEK 356
++ + ++ +++ +++ +E ++ K+E++ E R+ + ++
Sbjct: 430 QQLRREQQLRREQQLRREQEEERHEQKHEQERREQRL----------KREQEERRDWLKR 479
Query: 357 QNNLENIKNKLSAQLKLKMDDEDLRIRNAIAEKEEKFQNDETDKEKKRQDTLKSIEDHRK 536
+ E + + Q + +E+ R R E+EE+ +E++ Q + E+ R+
Sbjct: 480 EEETERHEQERRKQQLKRDQEEERRERWLKLEEEER----REQQERREQQLRREQEERRE 535
Query: 537 NTMKALEEDQRLNKQRDLDSLLARKE---ADAILKENEDRRQKMRLTEAKKLAEEHLATA 707
+K EE++RL ++ + L R++ + +LK E++R + E + E+
Sbjct: 536 QRLKRQEEEERLQQRLRSEQQLRREQEERLEQLLKREEEKRLEQERREQRLKREQEERRD 595
Query: 708 KAIKDSDENSMMNKLKIMEENQKLLDLEESVFQEYARKVIEHCEKGGRTHILLK 869
+ +K +E + + + EE + Q R+ +E E+ R LK
Sbjct: 596 QLLKREEER---------RQQRLKREQEERLEQRLKREEVERLEQEERRDERLK 640
Score = 47.4 bits (111), Expect = 5e-05
Identities = 45/229 (19%), Positives = 101/229 (44%), Gaps = 23/229 (10%)
Frame = +3
Query: 45 KAQIKYNQQIKEKELKDWNVEGENIRRLAVAHALEKQRLDQIEREERRFKMQE----YMQ 212
K Q+K +Q+ + +E W E RR ++ R +Q ER E+R K QE Q
Sbjct: 492 KQQLKRDQEEERRER--WLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQ 549
Query: 213 QMDDVKKMRE-----IDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXYDEKQNNLENI 377
++ +++R +++L E+++ + E++ + +
Sbjct: 550 RLRSEQQLRREQEERLEQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRL 609
Query: 378 KNKLSAQLKLKMDDEDLRIRNAIAEKEEKFQNDETDKEKKRQDTLKSIE----------- 524
K + +L+ ++ E++ ++E+ + +E ++E+ R + LKS E
Sbjct: 610 KREQEERLEQRLKREEVERLEQEERRDERLKREEPEEER-RHELLKSEEQEERRHEQLRR 668
Query: 525 ---DHRKNTMKALEEDQRLNKQRDLDSLLARKEADAILKENEDRRQKMR 662
+ R+ +K EE++RL ++ + R+E + +E E R++++
Sbjct: 669 EQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIK 717
Score = 46.6 bits (109), Expect = 9e-05
Identities = 53/315 (16%), Positives = 134/315 (42%), Gaps = 33/315 (10%)
Frame = +3
Query: 6 EKIRKSKENVEFVKAQIKYNQQIKEKELKDWNVEGENIRRLAVAHALEKQRLDQIEREER 185
+++R+ ++ E + +++ QQ++ K+ E RR +++R +Q ER E+
Sbjct: 284 QELRRERQEEEQQQQRLRREQQLRRKQ--------EEERR-----EQQEERREQQERREQ 330
Query: 186 RFKMQEYMQQMDDVKKMREIDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXYDEKQNN 365
+ + +E QQ+ ++ R +L+ E+++E +E++
Sbjct: 331 QEERRE--QQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQEEERREQ 388
Query: 366 LENIKNKLSAQLKLKMD-----------------------------DEDLRIRNAIAEKE 458
+ +L + +L+ + ++ LR + ++
Sbjct: 389 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 448
Query: 459 EKFQNDETDKEKKRQDTLKSIEDHRKNTMKALEEDQRLNKQRDLDSLLARKEADA----I 626
E+ ++++ ++++R+ LK ++ R++ +K EE +R ++R L +E + +
Sbjct: 449 EEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWL 508
Query: 627 LKENEDRRQKMRLTEAKKLAEEHLATAKAIKDSDENSMMNKLKIMEENQKLLDLEESVFQ 806
E E+RR++ E + E+ + +K +E + + ++ E Q + EE + Q
Sbjct: 509 KLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQ-RLRSEQQLRREQEERLEQ 567
Query: 807 EYARKVIEHCEKGGR 851
R+ + E+ R
Sbjct: 568 LLKREEEKRLEQERR 582
Score = 45.4 bits (106), Expect = 2e-04
Identities = 53/285 (18%), Positives = 124/285 (43%)
Frame = +3
Query: 6 EKIRKSKENVEFVKAQIKYNQQIKEKELKDWNVEGENIRRLAVAHALEKQRLDQIEREER 185
E+ RK + + + K ++ + +++ L++ E E ++R E++ + + +ER
Sbjct: 896 EEERKRRRHTLYAKPALQEQLRKEQQLLQE---EEEELQR-------EEREKRRRQEQER 945
Query: 186 RFKMQEYMQQMDDVKKMREIDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXYDEKQNN 365
+++ +E +QQ ++ E +K + +E + + R EK+
Sbjct: 946 QYREEEQLQQEEEQLLREEREKRRRQERERQYR-----KDKKLQQKEEQLLGEEPEKRRR 1000
Query: 366 LENIKNKLSAQLKLKMDDEDLRIRNAIAEKEEKFQNDETDKEKKRQDTLKSIEDHRKNTM 545
E K K + +L+ ++E L + E+ EK + E +++ +++D L+ E+
Sbjct: 1001 QEREK-KYREEEELQQEEEQL-----LREEREKRRRQEWERQYRKKDELQQEEEQLLREE 1054
Query: 546 KALEEDQRLNKQRDLDSLLARKEADAILKENEDRRQKMRLTEAKKLAEEHLATAKAIKDS 725
+ Q +Q + L ++E + +E E RR++ + +K E + +++
Sbjct: 1055 REKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREE 1114
Query: 726 DENSMMNKLKIMEENQKLLDLEESVFQEYARKVIEHCEKGGRTHI 860
E + +E ++ EE + QE + + E EK R +
Sbjct: 1115 PEK------RRRQERERQCREEEELQQEEEQLLREEREKRRRQEL 1153
Score = 44.7 bits (104), Expect = 3e-04
Identities = 46/223 (20%), Positives = 96/223 (43%), Gaps = 7/223 (3%)
Frame = +3
Query: 147 EKQRLDQIEREERRFKMQEYMQQMDDVKKMREIDKLKNEEDDEEIRIFXXXXXXXXXXXX 326
E++R E ++ R + +E ++Q D K E +L +E D + R
Sbjct: 1344 ERERKFLKEEQQLRLEEREQLRQDRDRKFREEEQQLSRQERDRKFR-----EEEQQVRRQ 1398
Query: 327 XXXXXXYDEKQNNLENIKNKLSAQLKLKMDDEDLRIRNA-----IAEKEEKFQNDETDKE 491
+E+Q + K + +L + E+ ++ E+E++ + E D+
Sbjct: 1399 ERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDR- 1457
Query: 492 KKRQDTLKSIEDHRKNTMKALEEDQRLNKQRDLDSLLARKEADAILKENEDRRQ--KMRL 665
K R+ L+S E RK LEE+Q+L++Q+ L ++ + + RRQ +
Sbjct: 1458 KFREQELRSQEPERK----FLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKF 1513
Query: 666 TEAKKLAEEHLATAKAIKDSDENSMMNKLKIMEENQKLLDLEE 794
E ++L +E + ++ D + + K+ + Q+ +E+
Sbjct: 1514 REEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMED 1556
Score = 43.9 bits (102), Expect = 6e-04
Identities = 51/289 (17%), Positives = 121/289 (41%), Gaps = 17/289 (5%)
Frame = +3
Query: 6 EKIRKSKENVEFVKAQIKYNQQIKEKELKD----WNVEGENIR---RLAVAHALEKQRLD 164
E+ R+ + +++ + + + QQ +E++ +D W E ++ R RL+ L +QR
Sbjct: 755 EEKRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRER 814
Query: 165 QIEREERRFKMQEYMQQMDDVKKMREIDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXX 344
Q+ EER+ + Q ++ + ++ K+ R + + E++
Sbjct: 815 QLRAEERQQREQRFLPEEEE-KEQRGRQRREREKE------------------------- 848
Query: 345 YDEKQNNLENIKNKLSAQLKLKMDDEDLRIRNAIAEKEEKFQNDETDKEKKRQDTLK--- 515
L+ ++E L+ R + +E+ + D+E++RQ+ +
Sbjct: 849 ------------------LQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRQEQRRDQK 890
Query: 516 ---SIEDHRKNTMKALEEDQRLNKQRDLDSLLARKEADAILKENEDRR----QKMRLTEA 674
+E+ RK L L +Q + L ++E + + +E ++R Q+ + E
Sbjct: 891 WRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREE 950
Query: 675 KKLAEEHLATAKAIKDSDENSMMNKLKIMEENQKLLDLEESVFQEYARK 821
++L +E + ++ ++ + + +++KL EE + E K
Sbjct: 951 EQLQQEEEQLLR--EEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEK 997
Score = 43.5 bits (101), Expect = 8e-04
Identities = 43/239 (17%), Positives = 108/239 (45%), Gaps = 11/239 (4%)
Frame = +3
Query: 6 EKIRKSKENVEFVKAQIKYNQQIKEKELKD-----WNVEGENIRRLAVAHALEKQRLDQI 170
+++R+ + +F++ + + +Q E++ ++ E E +RR + ++ +
Sbjct: 1653 QQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRP 1712
Query: 171 EREERRFKMQE---YMQQMDDVKKMREIDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXX 341
EREE++ + QE ++ + +++ RE +L+++E D + R
Sbjct: 1713 EREEQQLRRQERDRKFREEEQLRQGREEQQLRSQESDRKFR------------------- 1753
Query: 342 XYDEKQNNLENIKNKLSAQL---KLKMDDEDLRIRNAIAEKEEKFQNDETDKEKKRQDTL 512
+E+Q E + +L Q K + ++E L++ E++E+ E D++ + ++
Sbjct: 1754 --EEEQLRQEREEQQLRPQQRDGKYRWEEEQLQL-----EEQEQRLRQERDRQYRAEEQF 1806
Query: 513 KSIEDHRKNTMKALEEDQRLNKQRDLDSLLARKEADAILKENEDRRQKMRLTEAKKLAE 689
+ E R+ + +E+++ +Q E + L+E RRQ+ +++ E
Sbjct: 1807 ATQEKSRREEQELWQEEEQKRRQ----------ERERKLREEHIRRQQKEEQRHRQVGE 1855
Score = 42.7 bits (99), Expect = 0.001
Identities = 63/301 (20%), Positives = 136/301 (45%), Gaps = 26/301 (8%)
Frame = +3
Query: 6 EKIRKSKENVEFVKAQIKYNQQIKEKELKDWNVEGENIRRLAVAHALEKQRLDQ-IEREE 182
E+ RK +E + V+ Q + + ++E++ + E R+ L ++R +Q + R+E
Sbjct: 1383 ERDRKFREEEQQVRRQERERKFLEEEQ----QLRQERHRKFREEEQLLQEREEQQLHRQE 1438
Query: 183 RRFKMQEYMQQM---DDVKKMREIDKLKNEEDD----EEIRIFXXXXXXXXXXXXXXXXX 341
R K E QQ+ + +K RE +L+++E + EE +
Sbjct: 1439 RDRKFLEEEQQLRRQERDRKFRE-QELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLR 1497
Query: 342 XYDEKQNNLENIKNKLSAQLKLKMDDEDLRIRNAIAEKEEKFQNDETDKEKKRQDTLKSI 521
+ Q ++ K + +L+ + E+ ++ E++ KF+ +E K ++++ K +
Sbjct: 1498 RQERGQQRRQDRDRKFREEEQLRQEREEQQLSR--QERDRKFRLEE-QKVRRQEQERKFM 1554
Query: 522 EDHR-----------KNTMKALEEDQRLNKQRDLDSLLARKEADAILKENE------DRR 650
ED + + + ED++L ++R+ + L R+E D E E +R
Sbjct: 1555 EDEQQLRRQEGQQQLRQEDRKFREDEQLLQERE-EQQLHRQERDRKFLEEEPQLRRQERE 1613
Query: 651 QKMRLTEAKKLAEEHLATAKAIKDSDENSMMNKLKIMEENQKLLDLEESV-FQEYARKVI 827
Q++R +K EE + +++ +E +L+ E ++K + E+ + QE RK +
Sbjct: 1614 QQLRHDRDRKFREEE----QLLQEGEE----QQLRRQERDRKFREEEQQLRRQERERKFL 1665
Query: 828 E 830
+
Sbjct: 1666 Q 1666
Score = 42.4 bits (98), Expect = 0.002
Identities = 45/231 (19%), Positives = 104/231 (45%), Gaps = 4/231 (1%)
Frame = +3
Query: 150 KQRLDQIEREERRFKMQEYMQQMDDVKKMREIDKLKNEEDDEEIRIFXXXXXXXXXXXXX 329
+Q +Q+ REER + ++ +++ ++ + K K DE+ R
Sbjct: 1134 QQEEEQLLREEREKRRRQELERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAV 1193
Query: 330 XXXXXYDEKQNNLENIKNKLSAQLKLKMDDEDLRIRNAIAEKEEKFQNDETDKEKKRQDT 509
Y + + N E + +Q++ + +DL ++ + E++E+ D+E++R+
Sbjct: 1194 RDNKVYCKGREN-EQFRQLEDSQVRDRQSQQDL--QHLLGEQQER------DREQERR-R 1243
Query: 510 LKSIEDHRKNTMKALEEDQRLNKQRDLDSLLARKEADAILKENEDRRQKM----RLTEAK 677
+ H + E+Q+ K+RD S ++E + +E E++R++ + E +
Sbjct: 1244 WQQANRHFPEEEQLEREEQKEAKRRDRKS---QEEKQLLREEREEKRRRQETDRKFREEE 1300
Query: 678 KLAEEHLATAKAIKDSDENSMMNKLKIMEENQKLLDLEESVFQEYARKVIE 830
+L +E ++ D +L E+ +K L+ E+ + +E RK ++
Sbjct: 1301 QLLQEREEQPLLRQERDRKFREEELLHQEQGRKFLEEEQRLREERERKFLK 1351
Score = 41.6 bits (96), Expect = 0.003
Identities = 45/257 (17%), Positives = 107/257 (41%), Gaps = 2/257 (0%)
Frame = +3
Query: 57 KYNQQIKEKELKDWNVEGENIRRLAVAHALEKQRLDQIEREERRFKMQEYMQQMDDVKKM 236
+ +Q +E+EL + + E RL +QR Q EE + QE+ ++ + +
Sbjct: 138 RQKRQEQERELAEGEEQSEKQERL-------EQRDRQRRDEELWRQRQEWQEREERRAEE 190
Query: 237 REIDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXYDEKQNNLENIKNKLSAQLKLKMD 416
++ K E +E F +EKQ ++++ + +
Sbjct: 191 EQLQSCKGHETEE----FPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQE----EE 242
Query: 417 DEDLRIRNAIAEKEE-KFQNDETDKEKKRQDTLKSIEDHRKNTMKALEEDQRLNKQR-DL 590
+++ R R + KEE K Q +E ++++ Q+ + + + ++ +++ +QR
Sbjct: 243 EKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRR 302
Query: 591 DSLLARKEADAILKENEDRRQKMRLTEAKKLAEEHLATAKAIKDSDENSMMNKLKIMEEN 770
+ L RK+ + ++ E+RR++ E ++ E + + ++ + + E
Sbjct: 303 EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQ 362
Query: 771 QKLLDLEESVFQEYARK 821
Q + EE ++ R+
Sbjct: 363 QLRREQEEERREQQLRR 379
>sp|Q8K3M6|ERC2_RAT ERC protein 2 (CAZ-associated structural protein 1) (CAST1) (Cast)
(Cytomatrix protein p110)
Length = 957
Score = 53.5 bits (127), Expect = 7e-07
Identities = 67/299 (22%), Positives = 132/299 (44%), Gaps = 22/299 (7%)
Frame = +3
Query: 12 IRKSKENVEFVKAQIKYNQQIKEKELKDWNVEGENIRRLAVAHALEKQRLDQIERE--ER 185
IR ++ ++ +KA N + +E+E+K V + + + + KQ L + E E
Sbjct: 394 IRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKNDQLKQELSKKESELLAL 453
Query: 186 RFKMQEYMQQMDDVKKMREIDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXY-DEKQN 362
+ K++ Q D K+ I+ LK +E R + ++K
Sbjct: 454 QTKLETLSNQNSDCKQ--HIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTK 511
Query: 363 NLENI---KNKLSAQLKLKMDDEDLRIR--NAIAEKEEKFQNDETDKEKKR---QDTLKS 518
L+++ K L+ +++ D +++ R N + +K E Q DK+K+ +D +KS
Sbjct: 512 QLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKS 571
Query: 519 IEDHRKNT---MKALEED--------QRLNKQRDLDSLLARKEADAILKENEDRRQKMRL 665
++ NT + LEE +RL +QR+ D +E ++ KEN+D ++K+
Sbjct: 572 LQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNA 631
Query: 666 TEAKKLAEEHLATAKAIKDSDENSMMNKLKIMEENQKLLDLEESVFQEYARKVIEHCEK 842
+A+ +E ++ D E++ ++ + KL LE ++ Q+ E C K
Sbjct: 632 LQAELTEKE-----SSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKK-----EECNK 680
Score = 34.7 bits (78), Expect = 0.36
Identities = 41/189 (21%), Positives = 84/189 (44%), Gaps = 5/189 (2%)
Frame = +3
Query: 9 KIRKSKENVEFVK-AQIKYNQQIKEKELKDWNVEGENIRRLAVAHALEKQRLDQIEREER 185
+I K EN + K +I + + + +KD N + N++ LEK++ Q+ E R
Sbjct: 731 EILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKH---NQQLEKKKNAQLLEEVR 787
Query: 186 R--FKMQEYMQQMDDVKKMREIDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXYDEKQ 359
R F M + Q + + M ++K + E D + R+ EK+
Sbjct: 788 RREFSMVDNSQHLQIEELMNALEKTRQELDATKARLASTQQSLA-------------EKE 834
Query: 360 NNLENIKNKLSAQLKLKMDDEDLRIRNAIAEKEEKFQNDE--TDKEKKRQDTLKSIEDHR 533
+L N++ + QL+ ++ + + AI+EK+ E K+KK Q+ + +++ +
Sbjct: 835 AHLANLRMERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREK 894
Query: 534 KNTMKALEE 560
+ L++
Sbjct: 895 DRLVHQLKQ 903
>sp|P53352|INCE_CHICK Inner centromere protein
Length = 877
Score = 53.1 bits (126), Expect = 1e-06
Identities = 54/259 (20%), Positives = 120/259 (46%), Gaps = 8/259 (3%)
Frame = +3
Query: 42 VKAQIKYNQQIKEKELKDWNVEGENIRRLAVAHALEKQRLDQIEREERRFKMQEYMQQMD 221
+K+ IKYN ++ + + + +R+ A L KQ+ +E E++R + + +++ +
Sbjct: 488 IKSFIKYNTPLQHDPKEKERQKLQALRKKEEAEQLRKQK---VEEEKKRRQEEAKLRREE 544
Query: 222 DVKKMREI-DKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXYDEKQNNLENIKNKLSAQ 398
++K+ + ++ + E++ + RI +EK K A+
Sbjct: 545 RLRKVLQARERAEQLEEERKRRIEQKLALFDEKTEKAREERLAEEKIKKRAAAKKMEEAE 604
Query: 399 LKLKMDDEDLRIRNAIAEKEEKFQNDETDKEKK--RQDTLKSIEDHR-----KNTMKALE 557
+ + DE+ R + A+ ++EE+ ++ E ++KK Q+ + I + R + A E
Sbjct: 605 ARRR-QDEEARKQKALQQEEEERRHKELMQKKKEEEQERARKIAEQRQAEQEREKQLAAE 663
Query: 558 EDQRLNKQRDLDSLLARKEADAILKENEDRRQKMRLTEAKKLAEEHLATAKAIKDSDENS 737
+Q K+++ R +A+ K+ E + + RL + A+E L K+ +E
Sbjct: 664 REQERKKEQERKKEEERIQAE---KQREQQEKAARLQKEVLAAKEQLQKEMEKKEKEE-Q 719
Query: 738 MMNKLKIMEENQKLLDLEE 794
++ ++K E+ QK L E+
Sbjct: 720 LLAEMKRQEQEQKKLPEEQ 738
Score = 43.5 bits (101), Expect = 8e-04
Identities = 34/167 (20%), Positives = 76/167 (45%), Gaps = 2/167 (1%)
Frame = +3
Query: 75 KEKELKDWNVEGENIRRLAVAHALEKQRLDQIEREERRFKMQEYMQQMDDVKKMREIDKL 254
K ++ ++ + E I++ A A +E+ + + EE R Q+ +QQ ++ ++ +E+ +
Sbjct: 577 KTEKAREERLAEEKIKKRAAAKKMEEAEARRRQDEEAR--KQKALQQEEEERRHKELMQK 634
Query: 255 KNEEDDEEIRIFXXXXXXXXXXXXXXXXXXYDEKQNNLENIK--NKLSAQLKLKMDDEDL 428
K EE+ E R E++ E K ++ A+ + + ++
Sbjct: 635 KKEEEQERARKIAEQRQAEQEREKQLAAEREQERKKEQERKKEEERIQAEKQREQQEKAA 694
Query: 429 RIRNAIAEKEEKFQNDETDKEKKRQDTLKSIEDHRKNTMKALEEDQR 569
R++ + +E+ Q + KEK+ Q L + ++ K L E+Q+
Sbjct: 695 RLQKEVLAAKEQLQKEMEKKEKEEQ--LLAEMKRQEQEQKKLPEEQK 739
>sp|Q6PH08|ERC2_MOUSE ERC protein 2 (CAZ-associated structural protein 1) (CAST1)
Length = 957
Score = 52.4 bits (124), Expect = 2e-06
Identities = 68/299 (22%), Positives = 131/299 (43%), Gaps = 22/299 (7%)
Frame = +3
Query: 12 IRKSKENVEFVKAQIKYNQQIKEKELKDWNVEGENIRRLAVAHALEKQRLDQIERE--ER 185
IR ++ V+ +KA N + +E+E+K V + + + KQ L + E E
Sbjct: 394 IRDLEDEVQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLAL 453
Query: 186 RFKMQEYMQQMDDVKKMREIDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXY-DEKQN 362
+ K++ Q D K+ I+ LK +E R + ++K
Sbjct: 454 QTKLETLSNQNSDCKQ--HIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTK 511
Query: 363 NLENI---KNKLSAQLKLKMDDEDLRIR--NAIAEKEEKFQNDETDKEKKR---QDTLKS 518
L+++ K L+ +++ D +++ R N + +K E Q DK+K+ +D +KS
Sbjct: 512 QLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKS 571
Query: 519 IEDHRKNT---MKALEED--------QRLNKQRDLDSLLARKEADAILKENEDRRQKMRL 665
++ NT + LEE +RL +QR+ D +E ++ KEN+D ++K+
Sbjct: 572 LQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNA 631
Query: 666 TEAKKLAEEHLATAKAIKDSDENSMMNKLKIMEENQKLLDLEESVFQEYARKVIEHCEK 842
+A+ +E ++ D E++ ++ + KL LE ++ Q+ E C K
Sbjct: 632 LQAELTEKE-----SSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKK-----EECNK 680
Score = 31.2 bits (69), Expect = 4.0
Identities = 40/189 (21%), Positives = 83/189 (43%), Gaps = 5/189 (2%)
Frame = +3
Query: 9 KIRKSKENVEFVK-AQIKYNQQIKEKELKDWNVEGENIRRLAVAHALEKQRLDQIEREER 185
+I K EN + K +I + + + +KD N + + L LEK++ Q+ E R
Sbjct: 731 EILKEVENEKNDKDKKIAELESLTLRHMKDQN---KKVANLKYNQQLEKKKNAQLLEEVR 787
Query: 186 RFK--MQEYMQQMDDVKKMREIDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXYDEKQ 359
R + M + Q + + M ++K + E D + R+ EK+
Sbjct: 788 RREDSMVDNSQHLQIEELMNALEKTRQELDATKARLASTQQSLA-------------EKE 834
Query: 360 NNLENIKNKLSAQLKLKMDDEDLRIRNAIAEKEEKFQNDE--TDKEKKRQDTLKSIEDHR 533
+L N++ + QL+ ++ + + AI+EK+ E K+KK Q+ + +++ +
Sbjct: 835 AHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREK 894
Query: 534 KNTMKALEE 560
+ L++
Sbjct: 895 DRLVHQLKQ 903
>sp|P53278|YG3A_YEAST Hypothetical 92.7 kDa protein in ASN2-PHB1 intergenic region
Length = 816
Score = 52.4 bits (124), Expect = 2e-06
Identities = 61/270 (22%), Positives = 124/270 (45%), Gaps = 16/270 (5%)
Frame = +3
Query: 45 KAQIKYNQQIKEKELKDWNVEGENIRRLAVAHALEKQRLDQIEREERRFKMQEYMQQMDD 224
K ++ N+ +K+ + D N E N ++L + E + +++ + E + + +
Sbjct: 482 KIEVSKNRLVKK--IIDVNAEHNN-KKLMILKDTENMKNQKLQEKN------EVLDKQTN 532
Query: 225 VKKMREIDKLKNEEDDEEIRIFXXXXXXXXXXXXXXXXXXYDEKQNNLENIKNKLSAQLK 404
VK EID L NE+ + + +++ NL N+ +L AQ+
Sbjct: 533 VKS--EIDDLNNEKTNVQ--------------------KEFNDWTTNLSNLSQQLDAQI- 569
Query: 405 LKMDDEDLRIRNAIAEKEEKFQNDETDKEKKRQDTLKSIEDHRK------NTMKALEEDQ 566
+I N I K+ K QN+ + EKK++D + E+++K ++++E +
Sbjct: 570 -------FKI-NQINLKQGKVQNEIDNLEKKKEDLVTQTEENKKLHEKNVQVLESVENKE 621
Query: 567 RLNKQRDLDSLLAR--KEADAILKENEDRRQKM-----RLTEAKKLAEEHL-ATAKAIKD 722
L + D+D+ ++ E I +EN + + ++ RL + ++ EE L A+ K
Sbjct: 622 YLPQINDIDNQISSLLNEVTIIKQENANEKTQLSAITKRLEDERRAHEEQLKLEAEERKR 681
Query: 723 SDENSMMNKLKIMEE--NQKLLDLEESVFQ 806
+EN + + + +EE +Q LD E+ + Q
Sbjct: 682 KEENLLEKQRQELEEQAHQAQLDHEQQITQ 711
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,829,024
Number of Sequences: 369166
Number of extensions: 1032913
Number of successful extensions: 8579
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6533
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7994
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8742211660
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)