Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_021_M04
(880 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9UG63|ABCF2_HUMAN ATP-binding cassette sub-family F mem... 384 e-106
sp|Q99LE6|ABCF2_MOUSE ATP-binding cassette sub-family F mem... 383 e-106
sp|P40024|YEM6_YEAST Probable ATP-dependent transporter YER... 263 6e-70
sp|Q6MG08|ABCF1_RAT ATP-binding cassette sub-family F membe... 196 5e-50
sp|Q767L0|ABCF1_PIG ATP-binding cassette sub-family F member 1 195 1e-49
sp|Q6P542|ABCF1_MOUSE ATP-binding cassette sub-family F mem... 194 2e-49
sp|Q8NE71|ABCF1_HUMAN ATP-binding cassette sub-family F mem... 194 4e-49
sp|Q7YR37|ABCF1_PANTR ATP-binding cassette sub-family F mem... 194 4e-49
sp|P43535|GCN20_YEAST Protein GCN20 190 4e-48
sp|P44808|Y658_HAEIN Probable ABC transporter ATP-binding p... 174 2e-43
>sp|Q9UG63|ABCF2_HUMAN ATP-binding cassette sub-family F member 2 (Iron-inhibited ABC
transporter 2)
Length = 623
Score = 384 bits (985), Expect = e-106
Identities = 184/288 (63%), Positives = 224/288 (77%)
Frame = +2
Query: 5 NGCGKSTLFAVLSNNELPIPSHIDQFLLQREMPPSDKTALQAVMEADVEKIRLEKEAEYL 184
NG GKS L + + E+PIP HID + L REMPPSDKT L VME D E+ LEKEAE L
Sbjct: 120 NGIGKSMLLSAIGKREVPIPEHIDIYHLTREMPPSDKTPLHCVMEVDTERAMLEKEAERL 179
Query: 185 ALQDDTESQDRLIEVYERLXXXXXXXXXXXXXXXXFGLGFTKDMQNKEVKHFSGGWRMRI 364
A +D ++L+E+YERL GLGFT MQ K++K FSGGWRMR+
Sbjct: 180 AHED--AECEKLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRV 237
Query: 365 SLARALFVKPALLMLDEPTNHLDLNACVWLEKELSQYNRILLIISHSEDFLNGVCTNIVH 544
+LARALF++P +L+LDEPTNHLDL+ACVWLE+EL + RIL+++SHS+DFLNGVCTNI+H
Sbjct: 238 ALARALFIRPFMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIH 297
Query: 545 MQNKKLVYYGGNYDQYIMTKMELEENQMKKYKWEQDQMAHMKDYIARFGHGSRKLARQAQ 724
M NKKL YY GNYDQY+ T++ELEENQMK++ WEQDQ+AHMK+YIARFGHGS KLARQAQ
Sbjct: 298 MHNKKLKYYTGNYDQYVKTRLELEENQMKRFHWEQDQIAHMKNYIARFGHGSAKLARQAQ 357
Query: 725 SKEKTLKKMVDGGLTQKVIREKNLVFSFPSCGEIPPPVIQVQNVSFKY 868
SKEKTL+KM+ GLT++V+ +K L F FP CG+IPPPVI VQNVSFKY
Sbjct: 358 SKEKTLQKMMASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKY 405
Score = 56.6 bits (135), Expect = 9e-08
Identities = 31/115 (26%), Positives = 59/115 (51%), Gaps = 3/115 (2%)
Frame = +2
Query: 299 GFTKDMQNKEVKHFSGGWRMRISLARALFVKPALLMLDEPTNHLDLNACVWLEKELSQYN 478
G T Q +++ S G + R+ LA + P +L LDEPTNHLD+ L ++++
Sbjct: 504 GLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFLDEPTNHLDIETIDALADAINEFE 563
Query: 479 RILLIISHSEDFLNGVCTNIVHMQNKKLVYYGGN---YDQYIMTKMELEENQMKK 634
++++SH + V I + + + + G+ Y +++ +K+ EE Q+ K
Sbjct: 564 GGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILAYKEHLKSKLVDEEPQLTK 618
>sp|Q99LE6|ABCF2_MOUSE ATP-binding cassette sub-family F member 2
Length = 628
Score = 383 bits (983), Expect = e-106
Identities = 183/288 (63%), Positives = 225/288 (78%)
Frame = +2
Query: 5 NGCGKSTLFAVLSNNELPIPSHIDQFLLQREMPPSDKTALQAVMEADVEKIRLEKEAEYL 184
NG GKS L + + E+PIP HID + L REMPPS+KT LQ VME D E+ LE+EAE L
Sbjct: 125 NGIGKSMLLSAIGKREVPIPEHIDIYHLTREMPPSEKTPLQCVMEVDTERAMLEREAERL 184
Query: 185 ALQDDTESQDRLIEVYERLXXXXXXXXXXXXXXXXFGLGFTKDMQNKEVKHFSGGWRMRI 364
A +D ++L+E+YERL GLGFT MQ K++K FSGGWRMR+
Sbjct: 185 AHED--AECEKLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRV 242
Query: 365 SLARALFVKPALLMLDEPTNHLDLNACVWLEKELSQYNRILLIISHSEDFLNGVCTNIVH 544
+LARALF++P +L+LDEPTNHLDL+ACVWLE+EL + RIL+++SHS+DFLNGVCTNI+H
Sbjct: 243 ALARALFIRPFMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIH 302
Query: 545 MQNKKLVYYGGNYDQYIMTKMELEENQMKKYKWEQDQMAHMKDYIARFGHGSRKLARQAQ 724
M NKKL YY GNYDQY+ T++ELEENQMK++ WEQDQ+AHMK+YIARFGHGS KLARQAQ
Sbjct: 303 MHNKKLKYYTGNYDQYVKTRLELEENQMKRFHWEQDQIAHMKNYIARFGHGSAKLARQAQ 362
Query: 725 SKEKTLKKMVDGGLTQKVIREKNLVFSFPSCGEIPPPVIQVQNVSFKY 868
SKEKTL+KM+ GLT++V+ +K L F FP CG+IPPPVI VQNVSFKY
Sbjct: 363 SKEKTLQKMMASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKY 410
Score = 56.6 bits (135), Expect = 9e-08
Identities = 31/115 (26%), Positives = 59/115 (51%), Gaps = 3/115 (2%)
Frame = +2
Query: 299 GFTKDMQNKEVKHFSGGWRMRISLARALFVKPALLMLDEPTNHLDLNACVWLEKELSQYN 478
G T Q +++ S G + R+ LA + P +L LDEPTNHLD+ L ++++
Sbjct: 509 GLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFLDEPTNHLDIETIDALADAINEFE 568
Query: 479 RILLIISHSEDFLNGVCTNIVHMQNKKLVYYGGN---YDQYIMTKMELEENQMKK 634
++++SH + V I + + + + G+ Y +++ +K+ EE Q+ K
Sbjct: 569 GGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILAYKEHLKSKLVDEEPQLTK 623
>sp|P40024|YEM6_YEAST Probable ATP-dependent transporter YER036C
Length = 610
Score = 263 bits (671), Expect = 6e-70
Identities = 138/294 (46%), Positives = 189/294 (64%), Gaps = 2/294 (0%)
Frame = +2
Query: 2 QNGCGKSTLFAVLSNNELPIPSHIDQFLLQREMPPSDKTALQAVM-EADVEKIRLEKEAE 178
+NGCGKST L+ E PIP HID +LL PS+ +AL V+ EA E R+E E
Sbjct: 115 ENGCGKSTFLKALATREYPIPEHIDIYLLDEPAEPSELSALDYVVTEAQHELKRIEDLVE 174
Query: 179 YLALQDDTESQDRLIE-VYERLXXXXXXXXXXXXXXXXFGLGFTKDMQNKEVKHFSGGWR 355
L+D ES+ L+E +YER+ GLGF K K+ K SGGW+
Sbjct: 175 KTILEDGPESE--LLEPLYERMDSLDPDTFESRAAIILIGLGFNKKTILKKTKDMSGGWK 232
Query: 356 MRISLARALFVKPALLMLDEPTNHLDLNACVWLEKELSQYNRILLIISHSEDFLNGVCTN 535
MR++LA+ALFVKP LL+LD+PT HLDL ACVWLE+ L +++R L+++SHS+DFLNGVCTN
Sbjct: 233 MRVALAKALFVKPTLLLLDDPTAHLDLEACVWLEEYLKRFDRTLVLVSHSQDFLNGVCTN 292
Query: 536 IVHMQNKKLVYYGGNYDQYIMTKMELEENQMKKYKWEQDQMAHMKDYIARFGHGSRKLAR 715
++ M+ +KL YGGNYD Y T+ ELE NQMK+Y +Q+++ H+K +IA G + L +
Sbjct: 293 MIDMRAQKLTAYGGNYDSYHKTRSELETNQMKQYNKQQEEIQHIKKFIASAGTYA-NLVK 351
Query: 716 QAQSKEKTLKKMVDGGLTQKVIREKNLVFSFPSCGEIPPPVIQVQNVSFKYGAN 877
QA+S++K L KM GL Q V+ +K F FP +PPPV+ ++SF Y +N
Sbjct: 352 QAKSRQKILDKMEADGLVQPVVPDKVFSFRFPQVERLPPPVLAFDDISFHYESN 405
Score = 53.5 bits (127), Expect = 7e-07
Identities = 29/98 (29%), Positives = 52/98 (53%)
Frame = +2
Query: 299 GFTKDMQNKEVKHFSGGWRMRISLARALFVKPALLMLDEPTNHLDLNACVWLEKELSQYN 478
G T + Q ++ S G R R+ A +P +L+LDEPTN LD+ L ++++N
Sbjct: 503 GLTGEGQTVQMATLSEGQRSRVVFALLALEQPNVLLLDEPTNGLDIPTIDSLADAINEFN 562
Query: 479 RILLIISHSEDFLNGVCTNIVHMQNKKLVYYGGNYDQY 592
++++SH L+ + +I ++NK + G+ QY
Sbjct: 563 GGVVVVSHDFRLLDKIAQDIFVVENKTATRWDGSILQY 600
>sp|Q6MG08|ABCF1_RAT ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50)
Length = 839
Score = 196 bits (499), Expect = 5e-50
Identities = 115/307 (37%), Positives = 171/307 (55%), Gaps = 15/307 (4%)
Frame = +2
Query: 5 NGCGKSTLFAVLSNNELPIPSHIDQFLLQREMPPSDKTALQAVMEADVEKIRL---EKEA 175
NG GK+TL ++N L IP +ID L ++E+ + A+QAV+ AD +++RL EK
Sbjct: 332 NGKGKTTLLKHIANRALSIPPNIDVLLCEQEVVADETPAVQAVLRADTKRLRLLEEEKRL 391
Query: 176 EYLALQDDTESQDRLIEVYERLXXXXXXXXXXXXXXXXFGLGFTKDMQNKEVKHFSGGWR 355
+ Q D + ++L +VYE L GLGF +MQN+ + FSGGWR
Sbjct: 392 QGQLEQGDDTAAEKLEKVYEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWR 451
Query: 356 MRISLARALFVKPALLMLDEPTNHLDLNACVWLEKELSQYNRILLIISHSEDFLNGVCTN 535
MR+SLARALF++P LLMLDEPTNHLDLNA +WL L + + LLI+SH + FL+ VCT+
Sbjct: 452 MRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTD 511
Query: 536 IVHMQNKKLVYYGGNYDQYIMTKMELEENQMKKYKWEQDQMAHMKDYIARFGHGSRKLAR 715
I+H+ ++L YY GNY + + ++ +K+Y+ ++ ++ +K G S K A
Sbjct: 512 IIHLDTQRLHYYRGNYMTFKKMYQQKQKELLKQYEKQEKKLKELK-----AGGKSTKQA- 565
Query: 716 QAQSKEKTLKKM------------VDGGLTQKVIREKNLVFSFPSCGEIPPPVIQVQNVS 859
+ Q+KE +K D K RE + F+FP + PPV+ + V+
Sbjct: 566 EKQTKEVLTRKQQKCRRKNQDEESQDPPELLKRpreYTVRFTFPDPPPLSPPVLGLHGVT 625
Query: 860 FKYGANK 880
F Y K
Sbjct: 626 FGYEGQK 632
Score = 48.9 bits (115), Expect = 2e-05
Identities = 22/89 (24%), Positives = 48/89 (53%)
Frame = +2
Query: 326 EVKHFSGGWRMRISLARALFVKPALLMLDEPTNHLDLNACVWLEKELSQYNRILLIISHS 505
++ SGG + R+ A +P +L+LDEPTN+LD+ + L + +++Y ++++SH
Sbjct: 733 QICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHD 792
Query: 506 EDFLNGVCTNIVHMQNKKLVYYGGNYDQY 592
+ + ++ + + G++D Y
Sbjct: 793 ARLITETNCQLWVVEEQSVSQIDGDFDDY 821
>sp|Q767L0|ABCF1_PIG ATP-binding cassette sub-family F member 1
Length = 807
Score = 195 bits (496), Expect = 1e-49
Identities = 113/306 (36%), Positives = 175/306 (57%), Gaps = 14/306 (4%)
Frame = +2
Query: 5 NGCGKSTLFAVLSNNELPIPSHIDQFLLQREMPPSDKTALQAVMEADVEKIRLEKEAEYL 184
NG GK+TL ++N L IP +ID L ++E+ + A+QAV+ AD ++++L +E L
Sbjct: 300 NGKGKTTLLKHIANRALSIPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRL 359
Query: 185 ALQ----DDTESQDRLIEVYERLXXXXXXXXXXXXXXXXFGLGFTKDMQNKEVKHFSGGW 352
Q DDT + DRL +VYE L GLGF +MQN+ + FSGGW
Sbjct: 360 QGQLEQGDDTAA-DRLEKVYEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGW 418
Query: 353 RMRISLARALFVKPALLMLDEPTNHLDLNACVWLEKELSQYNRILLIISHSEDFLNGVCT 532
RMR+SLARALF++P LLMLDEPTNHLDLNA +WL L + + LLI+SH + FL+ VCT
Sbjct: 419 RMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCT 478
Query: 533 NIVHMQNKKLVYYGGNYDQYIMTKMELEENQMKKYKWEQDQMAHMKDYIARFGHGSRKLA 712
+I+H+ ++L YY GNY + + ++ +K+Y+ ++ ++ +K G +++
Sbjct: 479 DIIHLDAQRLHYYRGNYMTFKKMYQQKQKELLKQYEKQEKKLKELK----AGGKSTKQAE 534
Query: 713 RQ-----AQSKEKTLKKMVDGGLTQ-----KVIREKNLVFSFPSCGEIPPPVIQVQNVSF 862
+Q + ++K +K D + K +E + F+FP + PPV+ + V+F
Sbjct: 535 KQTKEALTRKQQKCRRKNQDEESQEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTF 594
Query: 863 KYGANK 880
Y K
Sbjct: 595 GYEGQK 600
Score = 51.2 bits (121), Expect = 4e-06
Identities = 44/197 (22%), Positives = 82/197 (41%), Gaps = 1/197 (0%)
Frame = +2
Query: 5 NGCGKSTLFAVLSNNELPIPSHIDQFLLQREMPPSDKTALQAVMEADVEKIRLEKE-AEY 181
NG GKSTL +L+ P + EM + + + + E++R+E+ EY
Sbjct: 622 NGVGKSTLLLLLTGKLTPT---------RGEMRKNHRLKIGFFNQQYAEQLRMEETPTEY 672
Query: 182 LALQDDTESQDRLIEVYERLXXXXXXXXXXXXXXXXFGLGFTKDMQNKEVKHFSGGWRMR 361
L + QD FGL ++ SGG + R
Sbjct: 673 LQRGFNLPYQDA------------------RKCLGRFGL--ESHAHTIQICKLSGGQKAR 712
Query: 362 ISLARALFVKPALLMLDEPTNHLDLNACVWLEKELSQYNRILLIISHSEDFLNGVCTNIV 541
+ A +P +L+LDEPTN+LD+ + L + +++Y ++++SH + +
Sbjct: 713 VVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLW 772
Query: 542 HMQNKKLVYYGGNYDQY 592
++ + + G++D Y
Sbjct: 773 VVEEQSVSQIDGDFDDY 789
>sp|Q6P542|ABCF1_MOUSE ATP-binding cassette sub-family F member 1
Length = 837
Score = 194 bits (494), Expect = 2e-49
Identities = 112/306 (36%), Positives = 175/306 (57%), Gaps = 14/306 (4%)
Frame = +2
Query: 5 NGCGKSTLFAVLSNNELPIPSHIDQFLLQREMPPSDKTALQAVMEADVEKIRLEKEAEYL 184
NG GK+TL ++N L IP +ID L ++E+ + A+QAV+ AD +++RL +E L
Sbjct: 330 NGKGKTTLLKHIANRALSIPPNIDVLLCEQEVVADETPAVQAVLRADTKRLRLLEEERRL 389
Query: 185 ALQ----DDTESQDRLIEVYERLXXXXXXXXXXXXXXXXFGLGFTKDMQNKEVKHFSGGW 352
Q DDT ++ +L +VYE L GLGF +MQN+ + FSGGW
Sbjct: 390 QGQLEQGDDTAAE-KLEKVYEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGW 448
Query: 353 RMRISLARALFVKPALLMLDEPTNHLDLNACVWLEKELSQYNRILLIISHSEDFLNGVCT 532
RMR+SLARALF++P LLMLDEPTNHLDLNA +WL L + + LLI+SH + FL+ VCT
Sbjct: 449 RMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCT 508
Query: 533 NIVHMQNKKLVYYGGNYDQYIMTKMELEENQMKKYKWEQDQMAHMKDYIARFGHGSRKLA 712
+I+H+ ++L YY GNY + + ++ +K+Y+ ++ ++ +K G +++
Sbjct: 509 DIIHLDTQRLHYYRGNYMTFKKMYQQKQKELLKQYEKQEKKLKELK----AGGKSTKQAE 564
Query: 713 RQ-----AQSKEKTLKKMVDGGLTQ-----KVIREKNLVFSFPSCGEIPPPVIQVQNVSF 862
+Q + ++K +K D + K +E + F+FP + PPV+ + V+F
Sbjct: 565 KQTKEVLTRKQQKCRRKNQDEESQEPPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTF 624
Query: 863 KYGANK 880
Y K
Sbjct: 625 GYEGQK 630
Score = 48.1 bits (113), Expect = 3e-05
Identities = 43/197 (21%), Positives = 79/197 (40%), Gaps = 1/197 (0%)
Frame = +2
Query: 5 NGCGKSTLFAVLSNNELPIPSHIDQFLLQREMPPSDKTALQAVMEADVEKIRLEKE-AEY 181
NG GKSTL +L+ P EM + + + + E++ +E+ EY
Sbjct: 652 NGVGKSTLLLLLTGKLTPTNG---------EMRKNHRLKIGFFNQQYAEQLHMEETPTEY 702
Query: 182 LALQDDTESQDRLIEVYERLXXXXXXXXXXXXXXXXFGLGFTKDMQNKEVKHFSGGWRMR 361
L + QD FGL ++ SGG + R
Sbjct: 703 LQRSFNLPYQDA------------------RKCLGRFGL--ESHAHTIQICKLSGGQKAR 742
Query: 362 ISLARALFVKPALLMLDEPTNHLDLNACVWLEKELSQYNRILLIISHSEDFLNGVCTNIV 541
+ A +P +L+LDEPTN+LD+ + L + ++ Y ++++SH + +
Sbjct: 743 VVFAELACREPDVLILDEPTNNLDIESIDALGEAINDYKGAVIVVSHDARLITETNCQLW 802
Query: 542 HMQNKKLVYYGGNYDQY 592
++ + + G++D Y
Sbjct: 803 VVEEQGVSQIDGDFDDY 819
>sp|Q8NE71|ABCF1_HUMAN ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50)
(TNF-alpha-stimulated ABC protein)
Length = 845
Score = 194 bits (492), Expect = 4e-49
Identities = 112/306 (36%), Positives = 175/306 (57%), Gaps = 14/306 (4%)
Frame = +2
Query: 5 NGCGKSTLFAVLSNNELPIPSHIDQFLLQREMPPSDKTALQAVMEADVEKIRLEKEAEYL 184
NG GK+TL ++N L IP +ID L ++E+ + A+QAV+ AD ++++L +E L
Sbjct: 338 NGKGKTTLLKHIANRALSIPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRL 397
Query: 185 ALQ----DDTESQDRLIEVYERLXXXXXXXXXXXXXXXXFGLGFTKDMQNKEVKHFSGGW 352
Q DDT ++ RL +VYE L GLGF +MQN+ + FSGGW
Sbjct: 398 QGQLEQGDDTAAE-RLEKVYEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGW 456
Query: 353 RMRISLARALFVKPALLMLDEPTNHLDLNACVWLEKELSQYNRILLIISHSEDFLNGVCT 532
RMR+SLARALF++P LLMLDEPTNHLDLNA +WL L + + LLI+SH + FL+ VCT
Sbjct: 457 RMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCT 516
Query: 533 NIVHMQNKKLVYYGGNYDQYIMTKMELEENQMKKYKWEQDQMAHMKDYIARFGHGSRKLA 712
+I+H+ ++L YY GNY + + ++ +K+Y+ ++ ++ +K G +++
Sbjct: 517 DIIHLDAQRLHYYRGNYMTFKKMYQQKQKELLKQYEKQEKKLKELK----AGGKSTKQAE 572
Query: 713 RQ-----AQSKEKTLKKMVDGGLTQ-----KVIREKNLVFSFPSCGEIPPPVIQVQNVSF 862
+Q + ++K +K D + K +E + F+FP + PPV+ + V+F
Sbjct: 573 KQTKEALTRKQQKCRRKNQDEESQEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTF 632
Query: 863 KYGANK 880
Y K
Sbjct: 633 GYQGQK 638
Score = 49.3 bits (116), Expect = 1e-05
Identities = 43/197 (21%), Positives = 81/197 (41%), Gaps = 1/197 (0%)
Frame = +2
Query: 5 NGCGKSTLFAVLSNNELPIPSHIDQFLLQREMPPSDKTALQAVMEADVEKIRLEKE-AEY 181
NG GKSTL +L+ P EM + + + + E++R+E+ EY
Sbjct: 660 NGVGKSTLLLLLTGKLTPTHG---------EMRKNHRLKIGFFNQQYAEQLRMEETPTEY 710
Query: 182 LALQDDTESQDRLIEVYERLXXXXXXXXXXXXXXXXFGLGFTKDMQNKEVKHFSGGWRMR 361
L + QD FGL ++ SGG + R
Sbjct: 711 LQRGFNLPYQDA------------------RKCLGRFGL--ESHAHTIQICKLSGGQKAR 750
Query: 362 ISLARALFVKPALLMLDEPTNHLDLNACVWLEKELSQYNRILLIISHSEDFLNGVCTNIV 541
+ A +P +L+LDEPTN+LD+ + L + +++Y ++++SH + +
Sbjct: 751 VVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLW 810
Query: 542 HMQNKKLVYYGGNYDQY 592
++ + + G+++ Y
Sbjct: 811 VVEEQSVSQIDGDFEDY 827
>sp|Q7YR37|ABCF1_PANTR ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50)
Length = 807
Score = 194 bits (492), Expect = 4e-49
Identities = 112/306 (36%), Positives = 175/306 (57%), Gaps = 14/306 (4%)
Frame = +2
Query: 5 NGCGKSTLFAVLSNNELPIPSHIDQFLLQREMPPSDKTALQAVMEADVEKIRLEKEAEYL 184
NG GK+TL ++N L IP +ID L ++E+ + A+QAV+ AD ++++L +E L
Sbjct: 300 NGKGKTTLLKHIANRALSIPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRL 359
Query: 185 ALQ----DDTESQDRLIEVYERLXXXXXXXXXXXXXXXXFGLGFTKDMQNKEVKHFSGGW 352
Q DDT ++ RL +VYE L GLGF +MQN+ + FSGGW
Sbjct: 360 QGQLEQGDDTAAE-RLEKVYEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGW 418
Query: 353 RMRISLARALFVKPALLMLDEPTNHLDLNACVWLEKELSQYNRILLIISHSEDFLNGVCT 532
RMR+SLARALF++P LLMLDEPTNHLDLNA +WL L + + LLI+SH + FL+ VCT
Sbjct: 419 RMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCT 478
Query: 533 NIVHMQNKKLVYYGGNYDQYIMTKMELEENQMKKYKWEQDQMAHMKDYIARFGHGSRKLA 712
+I+H+ ++L YY GNY + + ++ +K+Y+ ++ ++ +K G +++
Sbjct: 479 DIIHLDAQRLHYYRGNYMTFKKMYQQKQKELLKQYEKQEKKLKELK----AGGKSTKQAE 534
Query: 713 RQ-----AQSKEKTLKKMVDGGLTQ-----KVIREKNLVFSFPSCGEIPPPVIQVQNVSF 862
+Q + ++K +K D + K +E + F+FP + PPV+ + V+F
Sbjct: 535 KQTKEALTRKQQKCRRKNQDEESQEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTF 594
Query: 863 KYGANK 880
Y K
Sbjct: 595 GYEGQK 600
Score = 49.3 bits (116), Expect = 1e-05
Identities = 43/197 (21%), Positives = 81/197 (41%), Gaps = 1/197 (0%)
Frame = +2
Query: 5 NGCGKSTLFAVLSNNELPIPSHIDQFLLQREMPPSDKTALQAVMEADVEKIRLEKE-AEY 181
NG GKSTL +L+ P EM + + + + E++R+E+ EY
Sbjct: 622 NGVGKSTLLLLLTGKLTPTHG---------EMRKNHRLKIGFFNQQYAEQLRMEETPTEY 672
Query: 182 LALQDDTESQDRLIEVYERLXXXXXXXXXXXXXXXXFGLGFTKDMQNKEVKHFSGGWRMR 361
L + QD FGL ++ SGG + R
Sbjct: 673 LQRGFNLPYQDA------------------RKCLGRFGL--ESHAHTIQICKLSGGQKAR 712
Query: 362 ISLARALFVKPALLMLDEPTNHLDLNACVWLEKELSQYNRILLIISHSEDFLNGVCTNIV 541
+ A +P +L+LDEPTN+LD+ + L + +++Y ++++SH + +
Sbjct: 713 VVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLW 772
Query: 542 HMQNKKLVYYGGNYDQY 592
++ + + G+++ Y
Sbjct: 773 VVEEQSVSQIDGDFEDY 789
>sp|P43535|GCN20_YEAST Protein GCN20
Length = 752
Score = 190 bits (483), Expect = 4e-48
Identities = 110/316 (34%), Positives = 179/316 (56%), Gaps = 24/316 (7%)
Frame = +2
Query: 2 QNGCGKSTLFAVLSNNELPIPSHIDQFLLQREMPPSDKTALQAVMEADV----------- 148
QNG GKSTL LS EL +P H+ +++E+ D ALQ+V++ADV
Sbjct: 233 QNGIGKSTLLRALSRRELNVPKHVSILHVEQELRGDDTKALQSVLDADVWRKQLLSEEAK 292
Query: 149 --------EKIRLEKEAEYLALQD-DTESQD---RLIEVYERLXXXXXXXXXXXXXXXXF 292
+ +R E E + L ++ D E +D LI++ ++L +
Sbjct: 293 INERLKEMDVLRQEFEEDSLEVKKLDNEREDLDNHLIQISDKLVDMESDKAEARAASILY 352
Query: 293 GLGFTKDMQNKEVKHFSGGWRMRISLARALFVKPALLMLDEPTNHLDLNACVWLEKELSQ 472
GLGF+ + Q + FSGGWRMR+SLARALF +P LL+LDEP+N LD+ + +L + L
Sbjct: 353 GLGFSTEAQQQPTNSFSGGWRMRLSLARALFCQPDLLLLDEPSNMLDVPSIAYLAEYLKT 412
Query: 473 YNRILLIISHSEDFLNGVCTNIVHMQNKKLVYY-GGNYDQYIMTKMELEENQMKKYKWEQ 649
Y +L +SH FLN V T+I++ N++L YY G ++D + TK E +N ++Y +
Sbjct: 413 YPNTVLTVSHDRAFLNEVATDIIYQHNERLDYYRGQDFDTFYTTKEERRKNAQREYDNQM 472
Query: 650 DQMAHMKDYIARFGHGSRKLARQAQSKEKTLKKMVDGGLTQKVIREKNLVFSFPSCGEIP 829
H++++I ++ + + K +++AQS+ K L+K+ + + ++K + F FP C ++
Sbjct: 473 VYRKHLQEFIDKYRYNAAK-SQEAQSRIKKLEKL---PVLEPPEQDKTIDFKFPECDKLS 528
Query: 830 PPVIQVQNVSFKYGAN 877
PP+IQ+Q+VSF Y N
Sbjct: 529 PPIIQLQDVSFGYDEN 544
Score = 53.1 bits (126), Expect = 1e-06
Identities = 33/100 (33%), Positives = 51/100 (51%), Gaps = 1/100 (1%)
Frame = +2
Query: 290 FGLGFTKDMQNKEVKHFSGGWRMRISLARALFVKPALLMLDEPTNHLDLNACVWLEKELS 469
FG+ T +Q ++ SGG + R++ A P +L+LDEP+NHLD L + L
Sbjct: 637 FGITGTLGLQKMQL--LSGGQKSRVAFAALCLNNPHILVLDEPSNHLDTTGLDALVEALK 694
Query: 470 QYNRILLIISHSEDFLNGVCTNI-VHMQNKKLVYYGGNYD 586
+N +L++SH ++ VC I V Q + G YD
Sbjct: 695 NFNGGVLMVSHDISVIDSVCKEIWVSEQGTVKRFEGTIYD 734
>sp|P44808|Y658_HAEIN Probable ABC transporter ATP-binding protein HI0658
Length = 638
Score = 174 bits (442), Expect = 2e-43
Identities = 102/296 (34%), Positives = 165/296 (55%), Gaps = 6/296 (2%)
Frame = +2
Query: 2 QNGCGKSTLFAVLSNNELP------IPSHIDQFLLQREMPPSDKTALQAVMEADVEKIRL 163
+NGCGKS+LFA+L +P P++ + +E P D +A+ V++ D E RL
Sbjct: 35 KNGCGKSSLFALLKKELMPEGGEVNYPANWRVSWVNQETPALDISAIDYVIQGDREYCRL 94
Query: 164 EKEAEYLALQDDTESQDRLIEVYERLXXXXXXXXXXXXXXXXFGLGFTKDMQNKEVKHFS 343
+++ E ++D + + ++ +L GLGF+++ + VK FS
Sbjct: 95 QQKLERANERNDGNA---IARIHGQLETLDAWTIQSRAASLLHGLGFSQEETIQPVKAFS 151
Query: 344 GGWRMRISLARALFVKPALLMLDEPTNHLDLNACVWLEKELSQYNRILLIISHSEDFLNG 523
GGWRMR++LA+AL LL+LDEPTNHLDL+A +WLE+ L QY L++ISH DFL+
Sbjct: 152 GGWRMRLNLAQALLCPSDLLLLDEPTNHLDLDAVIWLERWLVQYQGTLVLISHDRDFLDP 211
Query: 524 VCTNIVHMQNKKLVYYGGNYDQYIMTKMELEENQMKKYKWEQDQMAHMKDYIARFGHGSR 703
+ T I+H++N+KL Y G+Y + + + Q Y+ +Q +++H++ YI RF +
Sbjct: 212 IVTKILHIENQKLNEYTGDYSSFEVQRATKLAQQTAMYRQQQQKISHLQKYIDRFKAKAT 271
Query: 704 KLARQAQSKEKTLKKMVDGGLTQKVIREKNLVFSFPSCGEIPPPVIQVQNVSFKYG 871
K A+QAQS+ K L++M L + F F +P P++ ++ S YG
Sbjct: 272 K-AKQAQSRMKALERM---ELIAPAYVDNPFTFEFRPPQSLPNPLVMIEQASAGYG 323
Score = 68.9 bits (167), Expect = 2e-11
Identities = 40/113 (35%), Positives = 60/113 (53%)
Frame = +2
Query: 302 FTKDMQNKEVKHFSGGWRMRISLARALFVKPALLMLDEPTNHLDLNACVWLEKELSQYNR 481
F D N+ VK FSGG + R+ LA ++ +P LL+LDEPTNHLDL+ L + L Y
Sbjct: 423 FHGDKVNQAVKSFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALVDYEG 482
Query: 482 ILLIISHSEDFLNGVCTNIVHMQNKKLVYYGGNYDQYIMTKMELEENQMKKYK 640
L+++SH L + +KK+ + G+ + Y K E+N + K
Sbjct: 483 SLVVVSHDRHLLRNTVEEFYLVHDKKVEEFKGDLEDY--QKWLSEQNSTSENK 533
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,000,736
Number of Sequences: 369166
Number of extensions: 1814612
Number of successful extensions: 6604
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5865
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6516
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8742211660
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)