Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_021_L06 (809 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P07154|CATL_RAT Cathepsin L precursor (Major excreted pr... 258 1e-68 sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) ... 256 5e-68 sp|P06797|CATL_MOUSE Cathepsin L precursor (Major excreted ... 253 6e-67 sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted ... 251 2e-66 sp|P43236|CATK_RABIT Cathepsin K precursor (OC-2 protein) 250 3e-66 sp|P55097|CATK_MOUSE Cathepsin K precursor 249 6e-66 sp|P43235|CATK_HUMAN Cathepsin K precursor (Cathepsin O) (C... 249 6e-66 sp|P61277|CATK_MACMU Cathepsin K precursor >gi|47117667|sp|... 249 6e-66 sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathe... 249 8e-66 sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathe... 248 1e-65
>sp|P07154|CATL_RAT Cathepsin L precursor (Major excreted protein) (MEP) (Cyclic protein 2) (CP-2) [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 334 Score = 258 bits (660), Expect = 1e-68 Identities = 138/266 (51%), Positives = 179/266 (67%), Gaps = 1/266 (0%) Frame = +1 Query: 13 ITSVLLLFTILLRSSAFKFQINEELNDEWNLYKTRYQKSYLSIVELTRRIIWEENLRYIQ 192 +T +LLL + L ++ + ++ N +W+ +K+ +++ Y + E RR +WE+N+R IQ Sbjct: 1 MTPLLLLAVLCLGTALATPKFDQTFNAQWHQWKSTHRRLYGTNEEEWRRAVWEKNMRMIQ 60 Query: 193 HHNLEYDLGKHSYYLGVNEYADLTHEEFKIKFLGLKPIDRNYSRTIFMPPENMDNYPKSV 372 HN EY GKH + + +N + D+T+EEF+ G + R +F P M PK+V Sbjct: 61 LHNGEYSNGKHGFTMEMNAFGDMTNEEFRQIVNGYRHQKHKKGR-LFQEPL-MLQIPKTV 118 Query: 373 DWRKKGYVTPVKNQGQCGSCWSFSTTGALEGQHFRKRKQLVSLSEQQLVDCSKDYQNNGC 552 DWR+KG VTPVKNQGQCGSCW+FS +G LEGQ F K +L+SLSEQ LVDCS D N GC Sbjct: 119 DWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHDQGNQGC 178 Query: 553 NGGLMDNAFQYIQKY-GLESEADYPYTAMDGPCKYDSTKVVAHCTGFVDIKKGNEKDLTK 729 NGGLMD AFQYI++ GL+SE YPY A DG CKY + VA+ TGFVDI + EK L K Sbjct: 179 NGGLMDFAFQYIKENGGLDSEESYPYEAKDGSCKYRAEYAVANDTGFVDIPQ-QEKALMK 237 Query: 730 AVATVGPISVAIDASRPSFQLYKGGI 807 AVATVGPISVA+DAS PS Q Y GI Sbjct: 238 AVATVGPISVAMDASHPSLQFYSSGI 263
>sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) (Cathepsin U) Length = 334 Score = 256 bits (654), Expect = 5e-68 Identities = 136/266 (51%), Positives = 176/266 (66%), Gaps = 1/266 (0%) Frame = +1 Query: 13 ITSVLLLFTILLRSSAFKFQINEELNDEWNLYKTRYQKSYLSIVELTRRIIWEENLRYIQ 192 ++ VL F + + S+ KF N L+ +W +K +++ Y + E RR +WE+N++ I+ Sbjct: 3 LSLVLAAFCLGIASAVPKFDQN--LDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE 60 Query: 193 HHNLEYDLGKHSYYLGVNEYADLTHEEFKIKFLGLKPIDRNYSRTIFMPPENMDNYPKSV 372 HN EY GKH + + +N + D+T+EEF+ + +G + +F P +D PKSV Sbjct: 61 LHNGEYSQGKHGFTMAMNAFGDMTNEEFR-QMMGCFRNQKFRKGKVFREPLFLD-LPKSV 118 Query: 373 DWRKKGYVTPVKNQGQCGSCWSFSTTGALEGQHFRKRKQLVSLSEQQLVDCSKDYQNNGC 552 DWRKKGYVTPVKNQ QCGSCW+FS TGALEGQ FRK +LVSLSEQ LVDCS+ N GC Sbjct: 119 DWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGC 178 Query: 553 NGGLMDNAFQYIQKY-GLESEADYPYTAMDGPCKYDSTKVVAHCTGFVDIKKGNEKDLTK 729 NGG M AFQY+++ GL+SE YPY A+D CKY VA+ TGF + G EK L K Sbjct: 179 NGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMK 238 Query: 730 AVATVGPISVAIDASRPSFQLYKGGI 807 AVATVGPISVA+DA SFQ YK GI Sbjct: 239 AVATVGPISVAMDAGHSSFQFYKSGI 264
>sp|P06797|CATL_MOUSE Cathepsin L precursor (Major excreted protein) (MEP) (p39 cysteine proteinase) [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 334 Score = 253 bits (645), Expect = 6e-67 Identities = 137/263 (52%), Positives = 176/263 (66%), Gaps = 1/263 (0%) Frame = +1 Query: 22 VLLLFTILLRSSAFKFQINEELNDEWNLYKTRYQKSYLSIVELTRRIIWEENLRYIQHHN 201 +LLL + L ++ + ++ + EW+ +K+ +++ Y + E RR IWE+N+R IQ HN Sbjct: 4 LLLLAVLCLGTALATPKFDQTFSAEWHQWKSTHRRLYGTNEEEWRRAIWEKNMRMIQLHN 63 Query: 202 LEYDLGKHSYYLGVNEYADLTHEEFKIKFLGLKPIDRNYSRTIFMPPENMDNYPKSVDWR 381 EY G+H + + +N + D+T+EEF+ G + R +F P M PKSVDWR Sbjct: 64 GEYSNGQHGFSMEMNAFGDMTNEEFRQVVNGYRHQKHKKGR-LFQEPL-MLKIPKSVDWR 121 Query: 382 KKGYVTPVKNQGQCGSCWSFSTTGALEGQHFRKRKQLVSLSEQQLVDCSKDYQNNGCNGG 561 +KG VTPVKNQGQCGSCW+FS +G LEGQ F K +L+SLSEQ LVDCS N GCNGG Sbjct: 122 EKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHAQGNQGCNGG 181 Query: 562 LMDNAFQYIQKY-GLESEADYPYTAMDGPCKYDSTKVVAHCTGFVDIKKGNEKDLTKAVA 738 LMD AFQYI++ GL+SE YPY A DG CKY + VA+ TGFVDI + EK L KAVA Sbjct: 182 LMDFAFQYIKENGGLDSEESYPYEAKDGSCKYRAEFAVANDTGFVDIPQ-QEKALMKAVA 240 Query: 739 TVGPISVAIDASRPSFQLYKGGI 807 TVGPISVA+DAS PS Q Y GI Sbjct: 241 TVGPISVAMDASHPSLQFYSSGI 263
>sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted protein) (MEP) [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 333 Score = 251 bits (640), Expect = 2e-66 Identities = 137/265 (51%), Positives = 171/265 (64%), Gaps = 1/265 (0%) Frame = +1 Query: 16 TSVLLLFTILLRSSAFKFQINEELNDEWNLYKTRYQKSYLSIVELTRRIIWEENLRYIQH 195 T +L F + + S+ F + L +W +K + + Y E RR +WE+N++ I+ Sbjct: 4 TLILAAFCLGIASATLTF--DHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIEL 61 Query: 196 HNLEYDLGKHSYYLGVNEYADLTHEEFKIKFLGLKPIDRNYSRTIFMPPENMDNYPKSVD 375 HN EY GKHS+ + +N + D+T EEF+ G + + +F P + P+SVD Sbjct: 62 HNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGK-VFQEPLFYEA-PRSVD 119 Query: 376 WRKKGYVTPVKNQGQCGSCWSFSTTGALEGQHFRKRKQLVSLSEQQLVDCSKDYQNNGCN 555 WR+KGYVTPVKNQGQCGSCW+FS TGALEGQ FRK +L+SLSEQ LVDCS N GCN Sbjct: 120 WREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCN 179 Query: 556 GGLMDNAFQYIQ-KYGLESEADYPYTAMDGPCKYDSTKVVAHCTGFVDIKKGNEKDLTKA 732 GGLMD AFQY+Q GL+SE YPY A + CKY+ VA+ TGFVDI K EK L KA Sbjct: 180 GGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QEKALMKA 238 Query: 733 VATVGPISVAIDASRPSFQLYKGGI 807 VATVGPISVAIDA SF YK GI Sbjct: 239 VATVGPISVAIDAGHESFLFYKEGI 263
>sp|P43236|CATK_RABIT Cathepsin K precursor (OC-2 protein) Length = 329 Score = 250 bits (639), Expect = 3e-66 Identities = 133/262 (50%), Positives = 170/262 (64%), Gaps = 3/262 (1%) Frame = +1 Query: 31 LFTILLRSSAFKFQINEELNDEWNLYKTRYQKSYLSIV-ELTRRIIWEENLRYIQHHNLE 207 L +LL +F E L+ +W L+K Y K Y S V E++RR+IWE+NL++I HNLE Sbjct: 4 LKVLLLPVVSFALHPEEILDTQWELWKKTYSKQYNSKVDEISRRLIWEKNLKHISIHNLE 63 Query: 208 YDLGKHSYYLGVNEYADLTHEEFKIKFLGLK-PIDRNYSRTIFMPPENMDNYPKSVDWRK 384 LG H+Y L +N D+T EE K GLK P R++S P+ P S+D+RK Sbjct: 64 ASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPPSRSHSNDTLYIPDWEGRTPDSIDYRK 123 Query: 385 KGYVTPVKNQGQCGSCWSFSTTGALEGQHFRKRKQLVSLSEQQLVDCSKDYQNNGCNGGL 564 KGYVTPVKNQGQCGSCW+FS+ GALEGQ +K +L++LS Q LVDC +N GC GG Sbjct: 124 KGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVS--ENYGCGGGY 181 Query: 565 MDNAFQYIQK-YGLESEADYPYTAMDGPCKYDSTKVVAHCTGFVDIKKGNEKDLTKAVAT 741 M NAFQY+Q+ G++SE YPY D C Y+ T A C G+ +I +GNEK L +AVA Sbjct: 182 MTNAFQYVQRNRGIDSEDAYPYVGQDESCMYNPTGKAAKCRGYREIPEGNEKALKRAVAR 241 Query: 742 VGPISVAIDASRPSFQLYKGGI 807 VGP+SVAIDAS SFQ Y G+ Sbjct: 242 VGPVSVAIDASLTSFQFYSKGV 263
>sp|P55097|CATK_MOUSE Cathepsin K precursor Length = 329 Score = 249 bits (636), Expect = 6e-66 Identities = 132/259 (50%), Positives = 168/259 (64%), Gaps = 3/259 (1%) Frame = +1 Query: 40 ILLRSSAFKFQINEELNDEWNLYKTRYQKSYLSIV-ELTRRIIWEENLRYIQHHNLEYDL 216 +LL +F E L+ +W L+K +QK Y S V E++RR+IWE+NL+ I HNLE L Sbjct: 7 LLLPMVSFALSPEEMLDTQWELWKKTHQKQYNSKVDEISRRLIWEKNLKQISAHNLEASL 66 Query: 217 GKHSYYLGVNEYADLTHEEFKIKFLGLK-PIDRNYSRTIFMPPENMDNYPKSVDWRKKGY 393 G H+Y L +N D+T EE K GL+ P R+YS PE P S+D+RKKGY Sbjct: 67 GVHTYELAMNHLGDMTSEEVVQKMTGLRIPPSRSYSNDTLYTPEWEGRVPDSIDYRKKGY 126 Query: 394 VTPVKNQGQCGSCWSFSTTGALEGQHFRKRKQLVSLSEQQLVDCSKDYQNNGCNGGLMDN 573 VTPVKNQGQCGSCW+FS+ GALEGQ +K +L++LS Q LVDC +N GC GG M Sbjct: 127 VTPVKNQGQCGSCWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVT--ENYGCGGGYMTT 184 Query: 574 AFQYIQKY-GLESEADYPYTAMDGPCKYDSTKVVAHCTGFVDIKKGNEKDLTKAVATVGP 750 AFQY+Q+ G++SE YPY D C Y++T A C G+ +I GNEK L +AVA VGP Sbjct: 185 AFQYVQQNGGIDSEDAYPYVGQDESCMYNATAKAAKCRGYREIPVGNEKALKRAVARVGP 244 Query: 751 ISVAIDASRPSFQLYKGGI 807 ISV+IDAS SFQ Y G+ Sbjct: 245 ISVSIDASLASFQFYSRGV 263
>sp|P43235|CATK_HUMAN Cathepsin K precursor (Cathepsin O) (Cathepsin X) (Cathepsin O2) Length = 329 Score = 249 bits (636), Expect = 6e-66 Identities = 133/262 (50%), Positives = 170/262 (64%), Gaps = 3/262 (1%) Frame = +1 Query: 31 LFTILLRSSAFKFQINEELNDEWNLYKTRYQKSYLSIV-ELTRRIIWEENLRYIQHHNLE 207 L +LL +F E L+ W L+K ++K Y + V E++RR+IWE+NL+YI HNLE Sbjct: 4 LKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLE 63 Query: 208 YDLGKHSYYLGVNEYADLTHEEFKIKFLGLK-PIDRNYSRTIFMPPENMDNYPKSVDWRK 384 LG H+Y L +N D+T EE K GLK P+ + S PE P SVD+RK Sbjct: 64 ASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRK 123 Query: 385 KGYVTPVKNQGQCGSCWSFSTTGALEGQHFRKRKQLVSLSEQQLVDCSKDYQNNGCNGGL 564 KGYVTPVKNQGQCGSCW+FS+ GALEGQ +K +L++LS Q LVDC +N+GC GG Sbjct: 124 KGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVS--ENDGCGGGY 181 Query: 565 MDNAFQYIQK-YGLESEADYPYTAMDGPCKYDSTKVVAHCTGFVDIKKGNEKDLTKAVAT 741 M NAFQY+QK G++SE YPY + C Y+ T A C G+ +I +GNEK L +AVA Sbjct: 182 MTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVAR 241 Query: 742 VGPISVAIDASRPSFQLYKGGI 807 VGP+SVAIDAS SFQ Y G+ Sbjct: 242 VGPVSVAIDASLTSFQFYSKGV 263
>sp|P61277|CATK_MACMU Cathepsin K precursor sp|P61276|CATK_MACFA Cathepsin K precursor Length = 329 Score = 249 bits (636), Expect = 6e-66 Identities = 133/262 (50%), Positives = 170/262 (64%), Gaps = 3/262 (1%) Frame = +1 Query: 31 LFTILLRSSAFKFQINEELNDEWNLYKTRYQKSYLSIV-ELTRRIIWEENLRYIQHHNLE 207 L +LL +F E L+ W L+K ++K Y S V E++RR+IWE+NL+YI HNLE Sbjct: 4 LKVLLLPVMSFALYPEEILDTHWELWKKTHRKQYNSKVDEISRRLIWEKNLKYISIHNLE 63 Query: 208 YDLGKHSYYLGVNEYADLTHEEFKIKFLGLK-PIDRNYSRTIFMPPENMDNYPKSVDWRK 384 LG H+Y L +N D+T+EE K GLK P + S P+ P SVD+RK Sbjct: 64 ASLGVHTYELAMNHLGDMTNEEVVQKMTGLKVPASHSRSNDTLYIPDWEGRAPDSVDYRK 123 Query: 385 KGYVTPVKNQGQCGSCWSFSTTGALEGQHFRKRKQLVSLSEQQLVDCSKDYQNNGCNGGL 564 KGYVTPVKNQGQCGSCW+FS+ GALEGQ +K +L++LS Q LVDC +N+GC GG Sbjct: 124 KGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVS--ENDGCGGGY 181 Query: 565 MDNAFQYIQK-YGLESEADYPYTAMDGPCKYDSTKVVAHCTGFVDIKKGNEKDLTKAVAT 741 M NAFQY+QK G++SE YPY + C Y+ T A C G+ +I +GNEK L +AVA Sbjct: 182 MTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVAR 241 Query: 742 VGPISVAIDASRPSFQLYKGGI 807 VGP+SVAIDAS SFQ Y G+ Sbjct: 242 VGPVSVAIDASLTSFQFYSKGV 263
>sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 334 Score = 249 bits (635), Expect = 8e-66 Identities = 134/248 (54%), Positives = 166/248 (66%), Gaps = 2/248 (0%) Frame = +1 Query: 70 QINEELNDEWNLYKTRYQKSYLSIVELTRRIIWEENLRYIQHHNLEYDLGKHSYYLGVNE 249 +++ L+ W+ +K +++ Y E RR +WE+N + I HN EY GKH++ + +N Sbjct: 20 KLDPNLDAHWHQWKATHRRLYGMNEEEWRRAVWEKNKKIIDLHNQEYSEGKHAFRMAMNA 79 Query: 250 YADLTHEEFKIKFLGLKPIDRNYSRTIFMPPENMDNYPKSVDWRKKGYVTPVKNQGQCGS 429 + D+T+EEF+ G + ++ +F P +D PKSVDW KKGYVTPVKNQGQCGS Sbjct: 80 FGDMTNEEFRQVMNGFQN-QKHKKGKLFHEPLLVD-VPKSVDWTKKGYVTPVKNQGQCGS 137 Query: 430 CWSFSTTGALEGQHFRKRKQLVSLSEQQLVDCSKDYQNNGCNGGLMDNAFQYIQ-KYGLE 606 CW+FS TGALEGQ FRK +LVSLSEQ LVDCS+ N GCNGGLMDNAFQYI+ GL+ Sbjct: 138 CWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRAQGNQGCNGGLMDNAFQYIKDNGGLD 197 Query: 607 SEADYPYTAMD-GPCKYDSTKVVAHCTGFVDIKKGNEKDLTKAVATVGPISVAIDASRPS 783 SE YPY A D C Y A+ TGFVDI + EK L KAVATVGPISVAIDA S Sbjct: 198 SEESYPYLATDTNSCNYKPECSAANDTGFVDIPQ-REKALMKAVATVGPISVAIDAGHTS 256 Query: 784 FQLYKGGI 807 FQ YK GI Sbjct: 257 FQFYKSGI 264
>sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 339 Score = 248 bits (634), Expect = 1e-65 Identities = 130/250 (52%), Positives = 168/250 (67%), Gaps = 9/250 (3%) Frame = +1 Query: 85 LNDEWNLYKTRYQKSYLSIVELTRRI-IWEENLRYIQHHNLEYDLGKHSYYLGVNEYADL 261 + +EW+ YK +++K+Y + VE R+ I+ EN I HN + GK SY LG+N+YAD+ Sbjct: 24 IKEEWHTYKLQHRKNYANEVEERFRMKIFNENRHKIAKHNQLFAQGKVSYKLGLNKYADM 83 Query: 262 THEEFKIKFLGLKPIDRNYSR-------TIFMPPENMDNYPKSVDWRKKGYVTPVKNQGQ 420 H EFK G R R ++PP ++ PKSVDWR+ G VT VK+QG Sbjct: 84 LHHEFKETMNGYNHTLRQLMRERTGLVGATYIPPAHV-TVPKSVDWREHGAVTGVKDQGH 142 Query: 421 CGSCWSFSTTGALEGQHFRKRKQLVSLSEQQLVDCSKDYQNNGCNGGLMDNAFQYIQ-KY 597 CGSCW+FS+TGALEGQHFRK LVSLSEQ LVDCS Y NNGCNGGLMDNAF+YI+ Sbjct: 143 CGSCWAFSSTGALEGQHFRKAGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNG 202 Query: 598 GLESEADYPYTAMDGPCKYDSTKVVAHCTGFVDIKKGNEKDLTKAVATVGPISVAIDASR 777 G+++E YPY +D C ++ + A TGFVDI +G+E+ + KAVAT+GP+SVAIDAS Sbjct: 203 GIDTEKSYPYEGIDDSCHFNKATIGATDTGFVDIPEGDEEKMKKAVATMGPVSVAIDASH 262 Query: 778 PSFQLYKGGI 807 SFQLY G+ Sbjct: 263 ESFQLYSEGV 272
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 90,066,907 Number of Sequences: 369166 Number of extensions: 1844330 Number of successful extensions: 5528 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4910 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5100 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 7715018400 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)