Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_021_I14
(846 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q96DB2|HDA11_HUMAN Histone deacetylase 11 (HD11) 271 2e-72
sp|Q9GKU5|HDA11_MACFA Histone deacetylase 11 (HD11) 271 2e-72
sp|Q91WA3|HDA11_MOUSE Histone deacetylase 11 (HD11) 266 5e-71
sp|P28606|YGLA_SYNP2 Hypothetical 34.1 kDa protein in glnA ... 128 2e-29
sp|Q56195|ACUC_STAXY Acetoin utilization protein acuC 88 3e-17
sp|Q8NW34|ACUC_STAAW Acetoin utilization protein acuC 86 1e-16
sp|O30107|Y130_ARCFU Hypothetical protein AF0130 85 2e-16
sp|P39067|ACUC_BACSU Acetoin utilization protein acuC 85 3e-16
sp|P64376|ACUC_STAAN Acetoin utilization protein acuC >gi|5... 83 1e-15
sp|Q92769|HDAC2_HUMAN Histone deacetylase 2 (HD2) 81 4e-15
>sp|Q96DB2|HDA11_HUMAN Histone deacetylase 11 (HD11)
Length = 347
Score = 271 bits (693), Expect = 2e-72
Identities = 140/266 (52%), Positives = 181/266 (68%), Gaps = 1/266 (0%)
Frame = +2
Query: 50 ITKNNITEAVEARDEELRIGHSSEYLNSLKKSLNVAKIVEVGLVAMIPNRFVQSRLLSKF 229
++ + + EA EA +E+L + H+ YLN LK S VA I E+ V +PN VQ ++L
Sbjct: 55 LSDSMLVEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPL 114
Query: 230 RYQVGGTIQAAKLALKRSWAINIGGGFHHASEDAGGGFCVYADISIAIKSI-QQENPDYK 406
R Q GGTI A KLA++R WAIN+GGGFHH S D GGGFC YADI++AIK + ++ +
Sbjct: 115 RTQTGGTIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISR 174
Query: 407 FMIIDLDAHQGNGHERDFTNDKNVFILDIYNEGIYPHDEEAKRGIDISVGLMSYTKDKEY 586
IIDLDAHQGNGHERDF +DK V+I+D+YN IYP D AK+ I V L T+D EY
Sbjct: 175 ATIIDLDAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEY 234
Query: 587 LEKLNENLDKAFDQFEPQLIVYNAGTDCLLGDPLGRLSISEKGIVDRDEIVFKKAKERKC 766
L+K+ N+ K+ + P ++VYNAGTD L GD LG LSIS GIV RDE+VF+ + R+
Sbjct: 235 LDKVERNIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRV 294
Query: 767 PIVMLTSGGYQHTNAAIIANSIWESF 844
PI+M+TSGGYQ A IIA+SI F
Sbjct: 295 PILMVTSGGYQKRTARIIADSILNLF 320
>sp|Q9GKU5|HDA11_MACFA Histone deacetylase 11 (HD11)
Length = 347
Score = 271 bits (693), Expect = 2e-72
Identities = 140/266 (52%), Positives = 181/266 (68%), Gaps = 1/266 (0%)
Frame = +2
Query: 50 ITKNNITEAVEARDEELRIGHSSEYLNSLKKSLNVAKIVEVGLVAMIPNRFVQSRLLSKF 229
++ + + EA EA +E+L + H+ YLN LK S VA I E+ V +PN VQ ++L
Sbjct: 55 LSDSMLVEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPL 114
Query: 230 RYQVGGTIQAAKLALKRSWAINIGGGFHHASEDAGGGFCVYADISIAIKSI-QQENPDYK 406
R Q GGTI A KLA++R WAIN+GGGFHH S D GGGFC YADI++AIK + ++ +
Sbjct: 115 RTQTGGTIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISR 174
Query: 407 FMIIDLDAHQGNGHERDFTNDKNVFILDIYNEGIYPHDEEAKRGIDISVGLMSYTKDKEY 586
IIDLDAHQGNGHERDF +DK V+I+D+YN IYP D AK+ I V L T+D EY
Sbjct: 175 ATIIDLDAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEY 234
Query: 587 LEKLNENLDKAFDQFEPQLIVYNAGTDCLLGDPLGRLSISEKGIVDRDEIVFKKAKERKC 766
L+K+ N++K+ + P ++VYNAGTD L GD LG LSIS GIV RDE+VF+ + R
Sbjct: 235 LDKVERNIEKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRHV 294
Query: 767 PIVMLTSGGYQHTNAAIIANSIWESF 844
PI+M+TSGGYQ A IIA+SI F
Sbjct: 295 PILMVTSGGYQKRTARIIADSILNLF 320
>sp|Q91WA3|HDA11_MOUSE Histone deacetylase 11 (HD11)
Length = 347
Score = 266 bits (680), Expect = 5e-71
Identities = 138/257 (53%), Positives = 174/257 (67%), Gaps = 1/257 (0%)
Frame = +2
Query: 65 ITEAVEARDEELRIGHSSEYLNSLKKSLNVAKIVEVGLVAMIPNRFVQSRLLSKFRYQVG 244
+ EA EA +E+L + H+ YLN LK S VA I E+ V +PN VQ ++L R Q G
Sbjct: 60 LVEAREASEEDLLVVHTRRYLNELKWSFVVATITEIPPVIFLPNFLVQRKVLRPLRTQTG 119
Query: 245 GTIQAAKLALKRSWAINIGGGFHHASEDAGGGFCVYADISIAIKSI-QQENPDYKFMIID 421
GTI A KLA++R WAIN+GGGFHH S D GGGFC YADI++AIK + ++ + IID
Sbjct: 120 GTIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIID 179
Query: 422 LDAHQGNGHERDFTNDKNVFILDIYNEGIYPHDEEAKRGIDISVGLMSYTKDKEYLEKLN 601
LDAHQGNGHERDF DK V+I+D+YN IYP D AK I V L T+D+EYLEK+
Sbjct: 180 LDAHQGNGHERDFMGDKRVYIMDVYNRHIYPGDRFAKEAIRRKVELEWGTEDEEYLEKVE 239
Query: 602 ENLDKAFDQFEPQLIVYNAGTDCLLGDPLGRLSISEKGIVDRDEIVFKKAKERKCPIVML 781
N+ ++ + P ++VYNAGTD L GD LG LSIS GIV RDE+VF+ + PI+M+
Sbjct: 240 RNVRRSLQEHLPDVVVYNAGTDVLEGDRLGGLSISPAGIVKRDEVVFRVVRAHDIPILMV 299
Query: 782 TSGGYQHTNAAIIANSI 832
TSGGYQ A IIA+SI
Sbjct: 300 TSGGYQKRTARIIADSI 316
>sp|P28606|YGLA_SYNP2 Hypothetical 34.1 kDa protein in glnA 3'region
Length = 310
Score = 128 bits (321), Expect = 2e-29
Identities = 68/186 (36%), Positives = 102/186 (54%)
Frame = +2
Query: 239 VGGTIQAAKLALKRSWAINIGGGFHHASEDAGGGFCVYADISIAIKSIQQENPDYKFMII 418
VGGTI A+LAL+ A N GG HHA G GFC+ D++IA ++IQQ + +I+
Sbjct: 106 VGGTILTAQLALEHGLACNTAGGTHHAFPGYGSGFCILNDLAIATRTIQQRGLAQRILIV 165
Query: 419 DLDAHQGNGHERDFTNDKNVFILDIYNEGIYPHDEEAKRGIDISVGLMSYTKDKEYLEKL 598
DLD HQG+G F +D VF ++ E +P K+ D+ +GL D YL+ L
Sbjct: 166 DLDVHQGDGTAFIFQDDPTVFTFSMHCEVNFP---SQKQRSDLDLGLPEGLDDDGYLQIL 222
Query: 599 NENLDKAFDQFEPQLIVYNAGTDCLLGDPLGRLSISEKGIVDRDEIVFKKAKERKCPIVM 778
+L+ Q +P L+ Y+AG D +GD LG+L+++ G+ R+ +V P+
Sbjct: 223 AHHLEDLLSQVKPDLVFYDAGVDTHVGDRLGKLAMTNTGLYRRERLVLSTCLAAGYPVAC 282
Query: 779 LTSGGY 796
+ GGY
Sbjct: 283 VIGGGY 288
>sp|Q56195|ACUC_STAXY Acetoin utilization protein acuC
Length = 385
Score = 88.2 bits (217), Expect = 3e-17
Identities = 64/252 (25%), Positives = 117/252 (46%), Gaps = 14/252 (5%)
Frame = +2
Query: 83 ARDEELRIGHSSEYLNSLKK-SLNVAKIVEVGLVAMIPNRFVQSRLLSKFRYQ-VGGTIQ 256
A D+EL + H+ +Y+ +++ S + E + +Q R++ K + VGG +
Sbjct: 56 ATDDELSLIHAYDYIQAIRHASHGILSENEAKKYGLDGEDTLQFRMMHKHSARIVGGALN 115
Query: 257 AAKLALKRSWA--INIGGGFHHASEDAGGGFCVYADISIAIKSIQQENPDYKFMIIDLDA 430
A + + ++GGG HH+ GFC+Y D++I I + Q+ + + + ID DA
Sbjct: 116 LADQIMSGTLTNGCHLGGGLHHSLPGRANGFCIYNDVAITISYLMQKY-NQRVLCIDTDA 174
Query: 431 HQGNGHERDFTNDKNVFILDIYNEG--IYP-------HDEEAKRGIDISVGLMSYTKDKE 583
H G+G + F + I I+ G ++P E G +++ L YT+D+
Sbjct: 175 HHGDGTQWSFYTNDQALIYSIHETGKFLFPGSGHYTERGAEKGFGYTVNIPLEPYTEDQS 234
Query: 584 YLEKLNENLDKAFDQFEPQLIVYNAGTDCLLGDPLGRLSISEKGIVDRDEIVFKKAKE-R 760
+L+ + ++ F+P +IV G D DPL +S + + + IV A
Sbjct: 235 FLDVFKQTIEPVVASFKPDIIVSVHGVDVHYLDPLTHMSCTLNTLYEIPYIVKSLADTYT 294
Query: 761 KCPIVMLTSGGY 796
+ ++M GGY
Sbjct: 295 QGKVIMFGGGGY 306
>sp|Q8NW34|ACUC_STAAW Acetoin utilization protein acuC
Length = 389
Score = 86.3 bits (212), Expect = 1e-16
Identities = 73/277 (26%), Positives = 126/277 (45%), Gaps = 22/277 (7%)
Frame = +2
Query: 32 SENLIN---ITKNNITEAVEARDEELRIGHSSEYLNSLKKS----LNVAKIVEVGLVAMI 190
+E L+N ++ I + A D+EL + H +Y+ ++K + ++ + + GL
Sbjct: 36 TELLLNANLLSPEQIVQPRIATDDELMLIHKYDYVEAIKHASHGIISEDEAKKYGL---- 91
Query: 191 PNRFVQSRLLSKFRYQ---VGGTIQAAKLAL--KRSWAINIGGGFHHASEDAGGGFCVYA 355
N S+ R+ VGG + A L + K ++GGG HHA GFC+Y
Sbjct: 92 -NDEENSQFKHMHRHSATIVGGALTLADLIMSGKVLNGCHLGGGLHHAQPGRASGFCIYN 150
Query: 356 DISIAIKSIQQENPDYKFMIIDLDAHQGNGHERDFTNDKNVFILDIYNEG--IYP----- 514
DI+I + + +E + + +IID DAH G+G + F D +V I+ G ++P
Sbjct: 151 DIAITAQYLAKEY-NQRVLIIDTDAHHGDGTQWSFYADNHVTTYSIHETGKFLFPGSGHY 209
Query: 515 --HDEEAKRGIDISVGLMSYTKDKEYLEKLNENLDKAFDQFEPQLIVYNAGTDCLLGDPL 688
E+ G ++V L YT+D +LE ++ F+P +I+ G D DPL
Sbjct: 210 TERGEDIGYGHTVNVPLEPYTEDASFLECFKLTVEPVVKSFKPDIILSVNGVDIHYRDPL 269
Query: 689 GRLSISEKGIVDRDEIV-FKKAKERKCPIVMLTSGGY 796
L+ + + + V + ++M GGY
Sbjct: 270 THLNCTLHSLYEIPYFVKYLADSYTNGKVIMFGGGGY 306
>sp|O30107|Y130_ARCFU Hypothetical protein AF0130
Length = 359
Score = 85.1 bits (209), Expect = 2e-16
Identities = 73/272 (26%), Positives = 128/272 (47%), Gaps = 19/272 (6%)
Frame = +2
Query: 65 ITEAVEARDEELRIGHSSEYLNSLKKSLNVAKIVEVGLVAMIPNRFVQSRLLSKFRYQVG 244
+ E +A E++ H+ EY+ L+ I++ IP LL+ G
Sbjct: 47 LLEPFKASLEDVLEVHTEEYVRFLEMESKKGGIIDFD--TNIPVGVFDRALLA-----AG 99
Query: 245 GTIQAAKLALKR----SWAINIGGGFHHASEDAGGGFCVYADISIAIKSIQQENPDYKFM 412
G I+AA+ L + ++A+ G HHA G GFC +++I +K + ++ + +
Sbjct: 100 GAIRAAQAVLNKECENAFAMIRPPG-HHAKPYIGAGFCYLNNMAIMVKWLLKQGFE-RIA 157
Query: 413 IIDLDAHQGNGHERDFTNDKNVFILDIYNEGIYP---HDEEAK----RGIDISVGLMSYT 571
I+D DAH G+G + F ND V + + +YP + EE G +++ L T
Sbjct: 158 ILDWDAHHGDGTQEIFYNDDRVLFISTHQMPLYPGTGYPEECGTGKGEGYTVNIPLPPGT 217
Query: 572 KDKEYLEKLNENLDKAFDQFEPQLIVYNAGTDCLLGDPLGRLSISEKGIVDRDEIVFKKA 751
D+ Y+ ++E ++ ++F+PQ I +AG D DP+ L+++ +G + A
Sbjct: 218 GDEGYMMVIDEIIEPVVNEFKPQFIAISAGQDNHFTDPITSLALTARGYAEMMRRAVAMA 277
Query: 752 KERKCP--IVMLTSGGYQ------HTNAAIIA 823
E+ C +V + GGY +TN IIA
Sbjct: 278 -EKHCDGRLVAVLEGGYSVEGALPYTNLGIIA 308
>sp|P39067|ACUC_BACSU Acetoin utilization protein acuC
Length = 387
Score = 84.7 bits (208), Expect = 3e-16
Identities = 63/221 (28%), Positives = 103/221 (46%), Gaps = 15/221 (6%)
Frame = +2
Query: 83 ARDEELRIGHSSEYLNSLKKS----LNVAKIVEVGLVAMIPNRFVQSRLLSKFRYQVGGT 250
A +EEL + H+ +Y+ ++K + L + GL F + VGGT
Sbjct: 52 ASEEELSLVHTDDYIQAVKLAGAGKLPAEEGESYGLGTEDTPVFAGMHEAASLL--VGGT 109
Query: 251 IQAAKLALKRS--WAINIGGGFHHASEDAGGGFCVYADISIAIKSIQQENPDYKFMIIDL 424
+ AA + A N+GGG HH GFC+Y D ++AI+ IQ++ + + ID
Sbjct: 110 LTAADWVMSGQALHAANLGGGLHHGFRGRASGFCIYNDSAVAIQYIQKKY-SARVLYIDT 168
Query: 425 DAHQGNGHERDFTNDKNVFILDIYNEG--IYPHDEEAKR-------GIDISVGLMSYTKD 577
DAH G+G + F ++ +V L I+ G ++P + + G ++ L ++T+D
Sbjct: 169 DAHHGDGVQFTFYDNPDVCTLSIHETGRYLFPGTGQIQEKGSGKGYGYSFNIPLDAFTED 228
Query: 578 KEYLEKLNENLDKAFDQFEPQLIVYNAGTDCLLGDPLGRLS 700
+LE + FEP +I+ G D DPL LS
Sbjct: 229 DSFLEAYRTAASEVAAYFEPDVIISQNGADAHYYDPLTHLS 269
>sp|P64376|ACUC_STAAN Acetoin utilization protein acuC
sp|P64375|ACUC_STAAM Acetoin utilization protein acuC
Length = 389
Score = 82.8 bits (203), Expect = 1e-15
Identities = 58/198 (29%), Positives = 92/198 (46%), Gaps = 12/198 (6%)
Frame = +2
Query: 239 VGGTIQAAKLAL--KRSWAINIGGGFHHASEDAGGGFCVYADISIAIKSIQQENPDYKFM 412
VGG + A L + K ++GGG HHA GFC+Y DI+I + I +E + + +
Sbjct: 110 VGGALTLADLIMSGKVLNGCHLGGGLHHAQPGRASGFCIYNDIAITAQYIAKEY-NQRVL 168
Query: 413 IIDLDAHQGNGHERDFTNDKNVFILDIYNEG--IYP-------HDEEAKRGIDISVGLMS 565
IID DAH G+G + F D +V I+ G ++P E+ G ++V L
Sbjct: 169 IIDTDAHHGDGTQWSFYADNHVTTYSIHETGKFLFPGSGHYTERGEDIGYGHTVNVPLEP 228
Query: 566 YTKDKEYLEKLNENLDKAFDQFEPQLIVYNAGTDCLLGDPLGRLSISEKGIVDRDEIV-F 742
YT+D +LE ++ F+P +I+ G D DPL L+ + + + V +
Sbjct: 229 YTEDASFLECFKLTVEPVVKSFKPDIILSVNGVDIHYRDPLTHLNCTLHSLYEIPYFVKY 288
Query: 743 KKAKERKCPIVMLTSGGY 796
++M GGY
Sbjct: 289 LADSYTNGKVIMFGGGGY 306
>sp|Q92769|HDAC2_HUMAN Histone deacetylase 2 (HD2)
Length = 488
Score = 80.9 bits (198), Expect = 4e-15
Identities = 76/273 (27%), Positives = 115/273 (42%), Gaps = 20/273 (7%)
Frame = +2
Query: 56 KNNITEAVEARDEELRIGHSSEYLNSLKKSLNVAKIVEVGLVAMIPNRF-------VQSR 214
K I +A EE+ HS EY+ L+ S+ + E RF V
Sbjct: 51 KMEIYRPHKATAEEMTKYHSDEYIKFLR-SIRPDNMSEYSKQMQ---RFNVGEDCPVFDG 106
Query: 215 LLSKFRYQVGGTIQAA-KLALKRS-WAINIGGGFHHASEDAGGGFCVYADISIAIKSIQQ 388
L + GG++ A KL +++ A+N GG HHA + GFC DI +AI + +
Sbjct: 107 LFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLK 166
Query: 389 ENPDYKFMIIDLDAHQGNGHERDFTNDKNVFILDIYNEGIY-PHDEEAKRGIDISVGLMS 565
+ + + ID+D H G+G E F V + + G Y P + + DI G
Sbjct: 167 YH--QRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLR---DIGAGKGK 221
Query: 566 Y----------TKDKEYLEKLNENLDKAFDQFEPQLIVYNAGTDCLLGDPLGRLSISEKG 715
Y D+ Y + + K + ++P +V G D L GD LG +++ KG
Sbjct: 222 YYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKG 281
Query: 716 IVDRDEIVFKKAKERKCPIVMLTSGGYQHTNAA 814
E+V K P++ML GGY N A
Sbjct: 282 HAKCVEVV----KTFNLPLLMLGGGGYTIRNVA 310
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,224,890
Number of Sequences: 369166
Number of extensions: 1792664
Number of successful extensions: 5216
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4919
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5106
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8293644780
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)