Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_021_H06 (336 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P04069|CBPB_ASTFL Carboxypeptidase B 60 2e-09 sp|P42788|CBPZ_SIMVI Zinc carboxypeptidase 47 1e-05 sp|Q7TPZ8|CBPA1_MOUSE Carboxypeptidase A1 precursor 46 3e-05 sp|P00731|CBPA1_RAT Carboxypeptidase A1 precursor 46 3e-05 sp|P00730|CBPA1_BOVIN Carboxypeptidase A1 precursor 45 5e-05 sp|Q6P8K8|CBPA4_MOUSE Carboxypeptidase A4 precursor 44 9e-05 sp|Q9JHH6|CBPB2_MOUSE Carboxypeptidase B2 precursor (Carbox... 44 2e-04 sp|Q96IY4|CBPB2_HUMAN Carboxypeptidase B2 precursor (Carbox... 43 2e-04 sp|P09954|CBPA1_PIG Carboxypeptidase A1 precursor 43 2e-04 sp|O02350|CBPA_ANOGA Zinc carboxypeptidase A precursor 43 2e-04
>sp|P04069|CBPB_ASTFL Carboxypeptidase B Length = 303 Score = 60.1 bits (144), Expect = 2e-09 Identities = 39/94 (41%), Positives = 51/94 (54%), Gaps = 1/94 (1%) Frame = +2 Query: 2 NSARGLVPNYETFY-VGSPPELLYAAAGGAYDWIKTKTKVKYAYTLELRPSREYTTGLAG 178 N+ L + T Y +GS +YAAAGG+ DW K + VKYAYT+ELR TG G Sbjct: 218 NAVDALTAVHGTRYEIGSSTNTIYAAAGGSDDWAKGEGGVKYAYTIELR-----DTGNYG 272 Query: 179 FLAPISYISRSGEEVYAGLLATVQAMTN*TKSKY 280 FL P + I +GEE + G V+ + N K Y Sbjct: 273 FLLPENQIIPTGEETFEG----VKVVANFVKDTY 302
>sp|P42788|CBPZ_SIMVI Zinc carboxypeptidase Length = 304 Score = 47.0 bits (110), Expect = 1e-05 Identities = 29/73 (39%), Positives = 38/73 (52%), Gaps = 1/73 (1%) Frame = +2 Query: 5 SARGLVPNYETFY-VGSPPELLYAAAGGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGF 181 +AR L Y T Y VG+ + +Y A+GG+ DW + AYT ELRP G GF Sbjct: 214 AARSLAQRYGTDYTVGNIYDAIYPASGGSMDWAYDTLDIPIAYTYELRP----RDGWNGF 269 Query: 182 LAPISYISRSGEE 220 P + I +GEE Sbjct: 270 QLPANQIIPTGEE 282
>sp|Q7TPZ8|CBPA1_MOUSE Carboxypeptidase A1 precursor Length = 419 Score = 45.8 bits (107), Expect = 3e-05 Identities = 27/67 (40%), Positives = 37/67 (55%) Frame = +2 Query: 38 FYVGSPPELLYAAAGGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGFLAPISYISRSGE 217 F GS + +Y A+G DW ++ +KY++T ELR TGL GFL P S I + E Sbjct: 348 FKYGSIIDTIYQASGSTIDWTYSQG-IKYSFTFELRD-----TGLRGFLLPASQIIPTAE 401 Query: 218 EVYAGLL 238 E + LL Sbjct: 402 ETWLALL 408
>sp|P00731|CBPA1_RAT Carboxypeptidase A1 precursor Length = 419 Score = 45.8 bits (107), Expect = 3e-05 Identities = 27/67 (40%), Positives = 37/67 (55%) Frame = +2 Query: 38 FYVGSPPELLYAAAGGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGFLAPISYISRSGE 217 F GS + +Y A+G DW ++ +KY++T ELR TGL GFL P S I + E Sbjct: 348 FKYGSIIDTIYQASGSTIDWTYSQG-IKYSFTFELRD-----TGLRGFLLPASQIIPTAE 401 Query: 218 EVYAGLL 238 E + LL Sbjct: 402 ETWLALL 408
>sp|P00730|CBPA1_BOVIN Carboxypeptidase A1 precursor Length = 419 Score = 45.1 bits (105), Expect = 5e-05 Identities = 29/79 (36%), Positives = 41/79 (51%), Gaps = 1/79 (1%) Frame = +2 Query: 29 YETFY-VGSPPELLYAAAGGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGFLAPISYIS 205 Y T Y GS +Y A+GG+ DW +KY++T ELR TG GFL P S I Sbjct: 344 YGTSYKYGSIITTIYQASGGSIDW-SYNQGIKYSFTFELR-----DTGRYGFLLPASQII 397 Query: 206 RSGEEVYAGLLATVQAMTN 262 + +E + G+L ++ N Sbjct: 398 PTAQETWLGVLTIMEHTLN 416
>sp|Q6P8K8|CBPA4_MOUSE Carboxypeptidase A4 precursor Length = 420 Score = 44.3 bits (103), Expect = 9e-05 Identities = 31/79 (39%), Positives = 40/79 (50%), Gaps = 1/79 (1%) Frame = +2 Query: 2 NSARGLVPNYETFY-VGSPPELLYAAAGGAYDWIKTKTKVKYAYTLELRPSREYTTGLAG 178 N+A+ L T Y VG +Y A+G + DW +KYA+T ELR TG G Sbjct: 336 NAAQALASLSGTKYRVGPTCTTVYPASGSSVDWAYDNG-IKYAFTFELR-----DTGYYG 389 Query: 179 FLAPISYISRSGEEVYAGL 235 FL P S I + EE + GL Sbjct: 390 FLLPASQIIPTAEETWLGL 408
>sp|Q9JHH6|CBPB2_MOUSE Carboxypeptidase B2 precursor (Carboxypeptidase U) (Thrombin-activatable fibrinolysis inhibitor) (TAFI) (Carboxypeptidase R) (CPR) Length = 422 Score = 43.5 bits (101), Expect = 2e-04 Identities = 30/71 (42%), Positives = 37/71 (52%), Gaps = 1/71 (1%) Frame = +2 Query: 26 NYETFYV-GSPPELLYAAAGGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGFLAPISYI 202 N T Y GS E LY A GG+ DWI +KY++T+ELR TG GFL P YI Sbjct: 347 NKNTRYTHGSGSESLYLAPGGSDDWI-YDLGIKYSFTIELR-----DTGRYGFLLPERYI 400 Query: 203 SRSGEEVYAGL 235 + E A + Sbjct: 401 KPTCAEALAAI 411
>sp|Q96IY4|CBPB2_HUMAN Carboxypeptidase B2 precursor (Carboxypeptidase U) (Thrombin-activatable fibrinolysis inhibitor) (TAFI) (Plasma carboxypeptidase B) (pCPB) Length = 423 Score = 43.1 bits (100), Expect = 2e-04 Identities = 26/63 (41%), Positives = 33/63 (52%) Frame = +2 Query: 47 GSPPELLYAAAGGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGFLAPISYISRSGEEVY 226 G E LY A GG DWI +KY++T+ELR TG GFL P YI + E + Sbjct: 356 GHGSETLYLAPGGGDDWI-YDLGIKYSFTIELR-----DTGTYGFLLPERYIKPTCREAF 409 Query: 227 AGL 235 A + Sbjct: 410 AAV 412
>sp|P09954|CBPA1_PIG Carboxypeptidase A1 precursor Length = 419 Score = 43.1 bits (100), Expect = 2e-04 Identities = 26/75 (34%), Positives = 38/75 (50%) Frame = +2 Query: 38 FYVGSPPELLYAAAGGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGFLAPISYISRSGE 217 F GS +Y A+GG DW + +KY+++ ELR TG GFL P S I + + Sbjct: 348 FQYGSIITTIYQASGGTIDWTYNQ-GIKYSFSFELR-----DTGRYGFLLPASQIIPTAQ 401 Query: 218 EVYAGLLATVQAMTN 262 E + LL ++ N Sbjct: 402 ETWLALLTIMEHTLN 416
>sp|O02350|CBPA_ANOGA Zinc carboxypeptidase A precursor Length = 433 Score = 43.1 bits (100), Expect = 2e-04 Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 1/83 (1%) Frame = +2 Query: 5 SARGLVPNYETFY-VGSPPELLYAAAGGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGF 181 + + L Y T Y G+ + +Y A+G + DW VK AYT ELRP + GF Sbjct: 342 TVKSLAKRYGTQYKYGNVIDAIYPASGSSVDWSYGAQDVKIAYTYELRPDGD---AWNGF 398 Query: 182 LAPISYISRSGEEVYAGLLATVQ 250 + P + I +GEE L+ ++ Sbjct: 399 VLPPNEIVPTGEETLDSLITLLE 421
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 33,680,330 Number of Sequences: 369166 Number of extensions: 538534 Number of successful extensions: 1294 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 1272 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1283 length of database: 68,354,980 effective HSP length: 79 effective length of database: 53,760,915 effective search space used: 1720349280 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)