Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_021_H01
(793 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q922H9|ZN330_MOUSE Zinc finger protein 330 (Nucleolar au... 359 4e-99
sp|O70524|ZN330_CRIGR Zinc finger protein 330 (Nucleolar au... 357 2e-98
sp|Q9Y3S2|ZN330_HUMAN Zinc finger protein 330 (Nucleolar au... 356 4e-98
sp|Q9VAU9|ZN330_DROME Zinc finger protein 330 homolog (Nucl... 355 6e-98
sp|Q60675|LAMA2_MOUSE Laminin alpha-2 chain precursor (Lami... 48 3e-05
sp|P15215|LAMC1_DROME Laminin gamma-1 chain precursor (Lami... 48 3e-05
sp|P24043|LAMA2_HUMAN Laminin alpha-2 chain precursor (Lami... 45 2e-04
sp|Q21313|LAML2_CAEEL Laminin-like protein K08C7.3 precursor 45 3e-04
sp|Q8CJ69|BMPER_MOUSE BMP-binding endothelial regulator pro... 40 0.009
sp|P18751|ZO71_XENLA Oocyte zinc finger protein XLCOF7.1 39 0.012
>sp|Q922H9|ZN330_MOUSE Zinc finger protein 330 (Nucleolar autoantigen 36)
Length = 316
Score = 359 bits (922), Expect = 4e-99
Identities = 151/222 (68%), Positives = 177/222 (79%)
Frame = +3
Query: 75 LYEHPCNSLMECDSCKRRQKNRAFCYFCYAIQRLPSCAHCGKQKCIMKGGDCLIKHVGIN 254
L +HPCN+ MECD C+RRQKNRAFCYFC ++Q+LP CA CGK KC+MK DC+IKH G+
Sbjct: 31 LAKHPCNASMECDKCQRRQKNRAFCYFCNSVQKLPICAQCGKTKCMMKSSDCVIKHAGVY 90
Query: 255 ATGMAMVGAVCDHCEAWVCHGANCVSVHGCECPLQNSDCVECQRGVWDHGGRIYICAFCD 434
+TG+AMVGA+CD CEAWVCHG C+S H C CPL +++CVEC+RGVWDHGGRI+ C+FC
Sbjct: 91 STGLAMVGAICDFCEAWVCHGRKCLSTHACACPLTDAECVECERGVWDHGGRIFSCSFCH 150
Query: 435 RYLCEDDQFEHQASCQRLDLETYKCVSCNRLGQFSCLRCKVCFCDEHIRRKGFKYDKNKN 614
+LCEDDQFEHQASCQ L+ ET+KCVSCNRLGQ SCLRCK CFCDEH R K FK +K K
Sbjct: 151 NFLCEDDQFEHQASCQVLEAETFKCVSCNRLGQHSCLRCKACFCDEHTRSKVFKQEKGKQ 210
Query: 615 LPCPKCGFETSETKDLSMSTKSYKYGRKGADEEQEDEDSDGY 740
PCPKCG ET ETKDLSMST+S K+GR+ EE D Y
Sbjct: 211 PPCPKCGHETQETKDLSMSTRSLKFGRQTGGEEDGASGYDAY 252
>sp|O70524|ZN330_CRIGR Zinc finger protein 330 (Nucleolar autoantigen 36)
Length = 317
Score = 357 bits (917), Expect = 2e-98
Identities = 151/222 (68%), Positives = 179/222 (80%)
Frame = +3
Query: 75 LYEHPCNSLMECDSCKRRQKNRAFCYFCYAIQRLPSCAHCGKQKCIMKGGDCLIKHVGIN 254
L +HPCN+ MECD C+RRQKNRAFCYFC ++Q+LP CA CGK KC+MK DC+IKH G+
Sbjct: 31 LAKHPCNASMECDKCQRRQKNRAFCYFCNSVQKLPICAQCGKTKCMMKSSDCVIKHAGVY 90
Query: 255 ATGMAMVGAVCDHCEAWVCHGANCVSVHGCECPLQNSDCVECQRGVWDHGGRIYICAFCD 434
+TG+AMVGA+CD CEAWVCHG C+S H C CPL +++CVEC+RGVWDHGGRI+ C+FC
Sbjct: 91 STGLAMVGAICDFCEAWVCHGRKCLSTHACACPLTDAECVECERGVWDHGGRIFSCSFCH 150
Query: 435 RYLCEDDQFEHQASCQRLDLETYKCVSCNRLGQFSCLRCKVCFCDEHIRRKGFKYDKNKN 614
+LCEDDQFEHQASCQ L+ ET+KCVSCNRLGQ SCLRCK CFCDEH R K FK +K K
Sbjct: 151 NFLCEDDQFEHQASCQVLEAETFKCVSCNRLGQHSCLRCKACFCDEHTRSKVFKQEKGKQ 210
Query: 615 LPCPKCGFETSETKDLSMSTKSYKYGRKGADEEQEDEDSDGY 740
PCPKCG ET ETKDLSMST+S K+GR+ E E + + GY
Sbjct: 211 PPCPKCGHETQETKDLSMSTRSLKFGRQTGGE--EGDGASGY 250
>sp|Q9Y3S2|ZN330_HUMAN Zinc finger protein 330 (Nucleolar autoantigen 36)
Length = 320
Score = 356 bits (914), Expect = 4e-98
Identities = 150/222 (67%), Positives = 179/222 (80%)
Frame = +3
Query: 75 LYEHPCNSLMECDSCKRRQKNRAFCYFCYAIQRLPSCAHCGKQKCIMKGGDCLIKHVGIN 254
L +HPCN+ MECD C+RRQKNRAFCYFC ++Q+LP CA CGK KC+MK DC+IKH G+
Sbjct: 31 LAKHPCNASMECDKCQRRQKNRAFCYFCNSVQKLPICAQCGKTKCMMKSSDCVIKHAGVY 90
Query: 255 ATGMAMVGAVCDHCEAWVCHGANCVSVHGCECPLQNSDCVECQRGVWDHGGRIYICAFCD 434
+TG+AMVGA+CD CEAWVCHG C+S H C CPL +++CVEC+RGVWDHGGRI+ C+FC
Sbjct: 91 STGLAMVGAICDFCEAWVCHGRKCLSTHACACPLTDAECVECERGVWDHGGRIFSCSFCH 150
Query: 435 RYLCEDDQFEHQASCQRLDLETYKCVSCNRLGQFSCLRCKVCFCDEHIRRKGFKYDKNKN 614
+LCEDDQFEHQASCQ L+ ET+KCVSCNRLGQ SCLRCK CFCD+H R K FK +K K
Sbjct: 151 NFLCEDDQFEHQASCQVLEAETFKCVSCNRLGQHSCLRCKACFCDDHTRSKVFKQEKGKQ 210
Query: 615 LPCPKCGFETSETKDLSMSTKSYKYGRKGADEEQEDEDSDGY 740
PCPKCG ET ETKDLSMST+S K+GR+ E E + + GY
Sbjct: 211 PPCPKCGHETQETKDLSMSTRSLKFGRQTGGE--EGDGASGY 250
>sp|Q9VAU9|ZN330_DROME Zinc finger protein 330 homolog (Nucleolar autoantigen 36 homolog)
Length = 315
Score = 355 bits (912), Expect = 6e-98
Identities = 145/233 (62%), Positives = 187/233 (80%)
Frame = +3
Query: 51 KFNSLQKTLYEHPCNSLMECDSCKRRQKNRAFCYFCYAIQRLPSCAHCGKQKCIMKGGDC 230
+ S + L + PCN+ MECD C+++QK+RAFCYFC +IQRLP CA CGK KC++K GDC
Sbjct: 21 EIRSREVPLADLPCNAPMECDKCEKKQKSRAFCYFCQSIQRLPICAQCGKIKCMLKTGDC 80
Query: 231 LIKHVGINATGMAMVGAVCDHCEAWVCHGANCVSVHGCECPLQNSDCVECQRGVWDHGGR 410
++KH G+ TG+ MVGA+CD CEAWVCHG C+ H C CPLQN+ C+EC+RGVW+HGGR
Sbjct: 81 VVKHPGVYTTGLGMVGAICDFCEAWVCHGRKCLQNHACTCPLQNATCLECERGVWEHGGR 140
Query: 411 IYICAFCDRYLCEDDQFEHQASCQRLDLETYKCVSCNRLGQFSCLRCKVCFCDEHIRRKG 590
I+ C+FC+ +LCEDDQFEHQASCQ L+ E YKC SCN+LGQ+SCLRCK C+C++H+RRKG
Sbjct: 141 IFKCSFCNGFLCEDDQFEHQASCQVLESENYKCQSCNKLGQYSCLRCKTCYCEDHVRRKG 200
Query: 591 FKYDKNKNLPCPKCGFETSETKDLSMSTKSYKYGRKGADEEQEDEDSDGYSFG 749
FKYDKNK +PCPKC ++TS TKDLSMST+S+K+GR+ +DE+ G +G
Sbjct: 201 FKYDKNKPIPCPKCNYDTSVTKDLSMSTRSHKFGRQQQGGNSDDEEGYGGYYG 253
>sp|Q60675|LAMA2_MOUSE Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy
chain)
Length = 3106
Score = 48.1 bits (113), Expect = 3e-05
Identities = 55/200 (27%), Positives = 68/200 (34%), Gaps = 24/200 (12%)
Frame = +3
Query: 105 ECDSCKRRQKN--RAFCYFCYAIQRLPSCAHCGKQKCIMKGGDCLIKHVGINATGMAMVG 278
+CD C N C C C+H G C K G C+ N TG
Sbjct: 991 KCDRCAHGYFNFQEGGCIAC-------DCSHLGNN-CDPKTGQCICPP---NTTGEK--- 1036
Query: 279 AVCDHC--EAWV------CHGANCVSVHG-----------CEC--PLQNSDCVECQRGVW 395
C C W C NC +V C C C EC RG W
Sbjct: 1037 --CSECLPNTWGHSIVTGCKVCNCSTVGSLASQCNVNTGQCSCHPKFSGMKCSECSRGHW 1094
Query: 396 DHGGRIYICAFCDRYLCEDDQFEHQASCQRLDLETYKCVSCNRLGQFSC-LRCKVCFCDE 572
++ +C CD +L D +C DLET KC ++ GQ SC + + CD
Sbjct: 1095 NYP----LCTLCDCFLPGTDA----TTC---DLETRKCSCSDQTGQCSCKVNVEGVHCD- 1142
Query: 573 HIRRKGFKYDKNKNLPCPKC 632
R F D L C C
Sbjct: 1143 RCRPGKFGLDAKNPLGCSSC 1162
Score = 30.0 bits (66), Expect = 7.5
Identities = 27/106 (25%), Positives = 34/106 (32%), Gaps = 6/106 (5%)
Frame = +3
Query: 84 HPCNSLMECDSCKRRQKNRAFCYFCYAIQRLPSCAHCG----KQKCIMKGGDCLIKHVGI 251
HP S M+C C R N C C C K C + G C K +
Sbjct: 1078 HPKFSGMKCSECSRGHWNYPLCTLCDCFLPGTDATTCDLETRKCSCSDQTGQCSCK---V 1134
Query: 252 NATGMAMVGAVCDHCE--AWVCHGANCVSVHGCECPLQNSDCVECQ 383
N G+ CD C + N + C C S C E +
Sbjct: 1135 NVEGVH-----CDRCRPGKFGLDAKNPLGCSSCYCFGVTSQCSEAK 1175
>sp|P15215|LAMC1_DROME Laminin gamma-1 chain precursor (Laminin B2 chain)
Length = 1639
Score = 47.8 bits (112), Expect = 3e-05
Identities = 44/147 (29%), Positives = 59/147 (40%), Gaps = 15/147 (10%)
Frame = +3
Query: 228 CLIKHVGINATGMAMVGAVCDHCEAWVCHG-------ANCVSVHG-CECP--LQNSDCVE 377
CL H G +A+ CD C + C V G C+C + DC E
Sbjct: 883 CLSGHFG---DPLALPHGRCDRCSCYEAGTEQDEQSITRCDQVTGQCQCKPNVIGRDCGE 939
Query: 378 CQRGVWD----HGGRIYICAFCDRYLCEDDQFEHQASCQRLDLETYKCVSC-NRLGQFSC 542
CQ G ++ +G +C Y D++ Q C R + +C C N FS
Sbjct: 940 CQPGYFNIRSGNGCENCLCDPVGSYNSTCDRYSGQCHC-RPGVMGQRCDQCENYFYGFSS 998
Query: 543 LRCKVCFCDEHIRRKGFKYDKNKNLPC 623
CK C CDE KGF+ D+N PC
Sbjct: 999 EGCKPCECDES-GSKGFQCDQNGQCPC 1024
>sp|P24043|LAMA2_HUMAN Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy
chain)
Length = 3110
Score = 45.1 bits (105), Expect = 2e-04
Identities = 49/192 (25%), Positives = 63/192 (32%), Gaps = 16/192 (8%)
Frame = +3
Query: 105 ECDSCKRRQKN--RAFCYFCYAIQRLPSCAHCGKQKCIMKGGDCLIKHVGINATGMAMVG 278
+CD C N C C C+H G C K G C+ I
Sbjct: 995 KCDRCAHGYFNFQEGGCTAC-------ECSHLGNN-CDPKTGRCICPPNTIGEKCSKCAP 1046
Query: 279 AVCDHCEAWVCHGANCVSVHG-----------CEC--PLQNSDCVECQRGVWDHGGRIYI 419
H C NC +V C C + C EC RG W++
Sbjct: 1047 NTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPR---- 1102
Query: 420 CAFCDRYLCEDDQFEHQASCQRLDLETYKCVSCNRLGQFSC-LRCKVCFCDEHIRRKGFK 596
C CD +L D +C D ET KC ++ GQ +C + + CD R F
Sbjct: 1103 CNLCDCFLPGTD----ATTC---DSETKKCSCSDQTGQCTCKVNVEGIHCD-RCRPGKFG 1154
Query: 597 YDKNKNLPCPKC 632
D L C C
Sbjct: 1155 LDAKNPLGCSSC 1166
>sp|Q21313|LAML2_CAEEL Laminin-like protein K08C7.3 precursor
Length = 3672
Score = 44.7 bits (104), Expect = 3e-04
Identities = 41/158 (25%), Positives = 56/158 (35%), Gaps = 32/158 (20%)
Frame = +3
Query: 183 CAHCGKQKCIMKGGDCLIKHVGINATGMAMVGAVCDHC--EAW------VCHGANC-VSV 335
C+ CG Q C K G C K IN G + CD C + W C G +C +
Sbjct: 1992 CSQCGSQYCDNKSGGCECK---INVEGDS-----CDRCKPDHWGFSKCQGCQGCHCGTAA 2043
Query: 336 HGCECPLQNSDCV-----------ECQRGVWDHGGRIYICAFCDRYLCEDDQF------- 461
+C ++N C C+ G W++G CD+ CE D
Sbjct: 2044 FNTQCNVENGQCTCRPGATGMRCEHCEHGYWNYGEH-----GCDKCDCEADLSMGTVCDV 2098
Query: 462 -EHQASCQRLDLETYKCVSC----NRLGQFSCLRCKVC 560
Q CQ +C C R+ + C RC C
Sbjct: 2099 RTGQCHCQE-GATGSRCDQCLPSYLRIPTYGCRRCDEC 2135
>sp|Q8CJ69|BMPER_MOUSE BMP-binding endothelial regulator protein precursor (Bone
morphogenetic protein-binding endothelial cell
precursor-derived regulator) (Crossveinless-2 protein)
(mCV2)
Length = 685
Score = 39.7 bits (91), Expect = 0.009
Identities = 40/180 (22%), Positives = 64/180 (35%), Gaps = 18/180 (10%)
Frame = +3
Query: 147 CYFCYAIQRLPSCAHCGKQKCIMKGGDCLIKHVGINATGMAMVGAVCDHCEAWVCHGANC 326
C C + + +C ++KC + DC A + GA C+ C+ G
Sbjct: 67 CIMCVCLNKEVTCK---REKCPVLSRDC--------ALAIKQRGACCERCKGCTHEGRTY 115
Query: 327 VSVHGCECPLQNSDCVECQRGV---------------WDHGGRIYICAFCDRYLCEDDQF 461
S + P + +CQ GV +H G C C + E Q+
Sbjct: 116 NSSFKWQTPAEPCVLRQCQEGVVTESEVRCVVHCKNPAEHQGA--CCPTCPGCVFEGVQY 173
Query: 462 EHQASCQRLDLETYKCVSCNRL-GQFSCLR--CKVCFCDEHIRRKGFKYDKNKNLPCPKC 632
Q E KC++C+ + G+ C+R C + C +H+ CPKC
Sbjct: 174 REGEEFQP---EGNKCITCSCVGGRTQCVREVCPILSCPQHLSH------TPSGQCCPKC 224
>sp|P18751|ZO71_XENLA Oocyte zinc finger protein XLCOF7.1
Length = 898
Score = 39.3 bits (90), Expect = 0.012
Identities = 43/206 (20%), Positives = 74/206 (35%), Gaps = 10/206 (4%)
Frame = +3
Query: 96 SLMECDSCKRRQKNRAFCYFCYAIQRLPSCAHCGKQKCIMKGGDCLIKHVGINATGMAMV 275
S EC C + A + ++ C+ CGK C D L H +
Sbjct: 455 SCSECGKCFTNHSHFAHHQMIHTGEKPFCCSKCGK--CFASSSD-LTFHRRTHTREKTFS 511
Query: 276 GAVCDHCEAWVCHGANCVSVHGCECPLQNSDCVEC---QRGVWDHGGRIYI------CAF 428
+ C C + H A +H E P S+C +C G+ H R ++ C+
Sbjct: 512 CSECGKCFSNHSHLARHQMIHTGEKPFCCSECGKCFSSSSGLTAHQQRTHMKVKPFSCSA 571
Query: 429 CDRYLCEDDQFEHQASCQRLDLETYKCVSCNRLGQFSCLRCKVCFCD-EHIRRKGFKYDK 605
C + R L ++ + FSC C+ CF + ++ R +
Sbjct: 572 CGKCFSN-----------RSHLIRHQMIHTGEK-PFSCFECRKCFSNPSNLARHQMTHTG 619
Query: 606 NKNLPCPKCGFETSETKDLSMSTKSY 683
K C +CG + + DL+ +++
Sbjct: 620 EKPFSCSECGKCFASSSDLTFHHRTH 645
Score = 36.2 bits (82), Expect = 0.10
Identities = 44/189 (23%), Positives = 62/189 (32%), Gaps = 10/189 (5%)
Frame = +3
Query: 96 SLMECDSCKRRQKNRAFCYFCYAIQRLPSCAHCGKQKCIMKGGDCLIKHVGINATGMAMV 275
S EC C + F + + ++ SC+ CGK C K L+ H +
Sbjct: 624 SCSECGKCFASSSDLTFHHRTHTGEKPFSCSECGK--CYSKKSS-LVHHQRTHTGEKPFS 680
Query: 276 GAVCDHCEAWVCHGANCVSVHGCECPLQNSDCVEC-------QRGVWDHGGRIYI-CAFC 431
+ CD C A H E S+C +C R H G I C C
Sbjct: 681 CSKCDKCFASSSELNIHQRTHTGEKAFSCSECGKCFTNRSQLSRHQMIHTGEKPISCPEC 740
Query: 432 DRYLCEDDQFE-HQASCQRLDLETYKCVSCNRLGQFSCLRCKVCFCD-EHIRRKGFKYDK 605
+ Q HQ R+ + FSCL C CF + + R +
Sbjct: 741 EECFVSSSQLTAHQQQAHRM------------VKPFSCLECGKCFSNRSNFARHQMIHTG 788
Query: 606 NKNLPCPKC 632
K C +C
Sbjct: 789 EKPFSCSEC 797
Score = 32.7 bits (73), Expect = 1.2
Identities = 40/183 (21%), Positives = 58/183 (31%), Gaps = 4/183 (2%)
Frame = +3
Query: 96 SLMECDSCKRRQKNRAFCYFCYAIQRLPSCAHCGKQKCIMKGGDCLIKHVGINATGMAMV 275
S EC C N A + ++ SC+ CG KC D H T
Sbjct: 596 SCFECRKCFSNPSNLARHQMTHTGEKPFSCSECG--KCFASSSDLTFHH----RTHTGEK 649
Query: 276 GAVCDHCEAWVCHGANCVSVHGCECPLQNSDCVECQRGVWDHGGRIYICAFCDRYLCEDD 455
C C +C + S V QR G + + C+ CD+
Sbjct: 650 PFSCSECG---------------KCYSKKSSLVHHQR--THTGEKPFSCSKCDKCFASSS 692
Query: 456 QFE-HQASCQRLDLETYKCVSCNRLGQ--FSCLRCKVCFCD-EHIRRKGFKYDKNKNLPC 623
+ HQ + G+ FSC C CF + + R + K + C
Sbjct: 693 ELNIHQRT---------------HTGEKAFSCSECGKCFTNRSQLSRHQMIHTGEKPISC 737
Query: 624 PKC 632
P+C
Sbjct: 738 PEC 740
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 91,283,041
Number of Sequences: 369166
Number of extensions: 2136257
Number of successful extensions: 7589
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6926
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7537
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7425705210
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)