Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_021_G12
(854 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P50458|LHX2_HUMAN LIM/homeobox protein Lhx2 (Homeobox pr... 121 2e-27
sp|Q9Z0S2|LHX2_MOUSE LIM/homeobox protein Lhx2 121 3e-27
sp|Q9NQ69|LHX9_HUMAN LIM/homeobox protein Lhx9 117 3e-26
sp|Q9WUH2|LHX9_MOUSE LIM/homeobox protein Lhx9 117 4e-26
sp|P36198|LHX2_RAT LIM/homeobox protein Lhx2 (Homeobox prot... 115 2e-25
sp|P29673|APTE_DROME Protein apterous 112 1e-24
sp|Q8IRC7|AWH_DROME LIM/homeobox protein Awh (Protein arrow... 74 5e-13
sp|O88706|LHX6_MOUSE LIM/homeobox protein Lhx6 72 3e-12
sp|O35652|LHX8_MOUSE LIM/homeobox protein Lhx8 (LIM homeodo... 71 3e-12
sp|Q9UPM6|LHX61_HUMAN LIM/homeobox protein Lhx6.1 (Lhx6) 71 4e-12
>sp|P50458|LHX2_HUMAN LIM/homeobox protein Lhx2 (Homeobox protein LH-2)
Length = 406
Score = 121 bits (304), Expect = 2e-27
Identities = 74/149 (49%), Positives = 94/149 (63%), Gaps = 2/149 (1%)
Frame = +1
Query: 52 RQKRVRTSFKHQQLRTMKAYFSMNHNPDSKDLRQLSQKTGLSKRVLQVWFQNARAKFRRS 231
+ KR+RTSFKH QLRTMK+YF++NHNPD+KDL+QL+QKTGL+KRVLQVWFQNARAKFRR+
Sbjct: 265 KTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRN 324
Query: 232 LCRQ--TGVMCGPSANQLQMPNVFDDNSLISIDKNGNYSTKTKMTTFNDISSSILNHSVQ 405
L RQ TGV A LQ S +S N + S + TT D++S L
Sbjct: 325 LLRQENTGVDKSTDA-ALQTGTPSGPASELS---NASLSPSSTPTTLTDLTSPTLPTVTS 380
Query: 406 NNHRLCSMNELNYQNQNTNGPLQTTMTNL 492
+ + N + + P QTT+TNL
Sbjct: 381 ----VLTSVPGNLEGHEPHSPSQTTLTNL 405
>sp|Q9Z0S2|LHX2_MOUSE LIM/homeobox protein Lhx2
Length = 406
Score = 121 bits (303), Expect = 3e-27
Identities = 74/149 (49%), Positives = 94/149 (63%), Gaps = 2/149 (1%)
Frame = +1
Query: 52 RQKRVRTSFKHQQLRTMKAYFSMNHNPDSKDLRQLSQKTGLSKRVLQVWFQNARAKFRRS 231
+ KR+RTSFKH QLRTMK+YF++NHNPD+KDL+QL+QKTGL+KRVLQVWFQNARAKFRR+
Sbjct: 265 KTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRN 324
Query: 232 LCRQ--TGVMCGPSANQLQMPNVFDDNSLISIDKNGNYSTKTKMTTFNDISSSILNHSVQ 405
L RQ TGV A LQ S +S N + S + TT D++S L
Sbjct: 325 LLRQENTGVDKTSDAT-LQTGTPSGPASELS---NASLSPSSTPTTLTDLTSPTLPTVTS 380
Query: 406 NNHRLCSMNELNYQNQNTNGPLQTTMTNL 492
+ + N + + P QTT+TNL
Sbjct: 381 ----VLTSVPGNLEGHEPHSPSQTTLTNL 405
>sp|Q9NQ69|LHX9_HUMAN LIM/homeobox protein Lhx9
Length = 388
Score = 117 bits (294), Expect = 3e-26
Identities = 67/148 (45%), Positives = 89/148 (60%), Gaps = 1/148 (0%)
Frame = +1
Query: 52 RQKRVRTSFKHQQLRTMKAYFSMNHNPDSKDLRQLSQKTGLSKRVLQVWFQNARAKFRRS 231
+ KR+RTSFKH QLRTMK+YF++NHNPD+KDL+QL+QKTGL+KRVLQVWFQNARAKFRR+
Sbjct: 257 KTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRN 316
Query: 232 LCRQ-TGVMCGPSANQLQMPNVFDDNSLISIDKNGNYSTKTKMTTFNDISSSILNHSVQN 408
L RQ G + L P D +L + TT D+++ +
Sbjct: 317 LLRQENGGVDKADGTSLPAPPSADSGAL---------TPPGTATTLTDLTNPTIT----- 362
Query: 409 NHRLCSMNELNYQNQNTNGPLQTTMTNL 492
+ + N + + P QTT+TNL
Sbjct: 363 ---VVTSVTSNMDSHESGSPSQTTLTNL 387
>sp|Q9WUH2|LHX9_MOUSE LIM/homeobox protein Lhx9
Length = 388
Score = 117 bits (293), Expect = 4e-26
Identities = 67/148 (45%), Positives = 88/148 (59%), Gaps = 1/148 (0%)
Frame = +1
Query: 52 RQKRVRTSFKHQQLRTMKAYFSMNHNPDSKDLRQLSQKTGLSKRVLQVWFQNARAKFRRS 231
+ KR+RTSFKH QLRTMK+YF++NHNPD+KDL+QL+QKTGL+KRVLQVWFQNARAKFRR+
Sbjct: 257 KTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRN 316
Query: 232 LCRQ-TGVMCGPSANQLQMPNVFDDNSLISIDKNGNYSTKTKMTTFNDISSSILNHSVQN 408
L RQ G + L P D +L T T +T + + +++ +
Sbjct: 317 LLRQENGGVDKADGTSLPAPPSADSGALTP------PGTATTLTDLTNPTVTVVTTVIS- 369
Query: 409 NHRLCSMNELNYQNQNTNGPLQTTMTNL 492
N + P QTT+TNL
Sbjct: 370 ----------NMDSHEPGSPSQTTLTNL 387
>sp|P36198|LHX2_RAT LIM/homeobox protein Lhx2 (Homeobox protein LH-2)
Length = 426
Score = 115 bits (288), Expect = 2e-25
Identities = 66/115 (57%), Positives = 81/115 (70%), Gaps = 2/115 (1%)
Frame = +1
Query: 52 RQKRVRTSFKHQQLRTMKAYFSMNHNPDSKDLRQLSQKTGLSKRVLQVWFQNARAKFRRS 231
+ KR+RTSFKH QLRTMK+YF++NHNPD+KDL+QL+QKTGL+KRVLQVWFQNARAKFRR+
Sbjct: 263 KTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRN 322
Query: 232 LCRQ--TGVMCGPSANQLQMPNVFDDNSLISIDKNGNYSTKTKMTTFNDISSSIL 390
L RQ TGV A LQ S +S N + S + TT D++S L
Sbjct: 323 LLRQENTGVDKTSDAT-LQTGTPSGPASELS---NASLSPSSTPTTLTDLTSPTL 373
>sp|P29673|APTE_DROME Protein apterous
Length = 469
Score = 112 bits (281), Expect = 1e-24
Identities = 52/70 (74%), Positives = 63/70 (90%)
Frame = +1
Query: 40 SNNLRQKRVRTSFKHQQLRTMKAYFSMNHNPDSKDLRQLSQKTGLSKRVLQVWFQNARAK 219
S++ R KR+RTSFKH QLRTMK+YF++NHNPD+KDL+QLSQKTGL KRVLQVWFQNARAK
Sbjct: 362 SSSSRTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLSQKTGLPKRVLQVWFQNARAK 421
Query: 220 FRRSLCRQTG 249
+RR + +Q G
Sbjct: 422 WRRMMMKQDG 431
>sp|Q8IRC7|AWH_DROME LIM/homeobox protein Awh (Protein arrowhead)
Length = 275
Score = 73.9 bits (180), Expect = 5e-13
Identities = 39/112 (34%), Positives = 65/112 (58%), Gaps = 6/112 (5%)
Frame = +1
Query: 19 QGLSKKGSNNLRQKRVRTSFKHQQLRTMKAYFSMNHNPDSKDLRQLSQKTGLSKRVLQVW 198
+G G + + KRVRT+F +QL+ ++A F ++ NPD +DL +++ TGLSKRV QVW
Sbjct: 136 EGCDGDGYHKSKTKRVRTTFTEEQLQVLQANFQIDSNPDGQDLERIASVTGLSKRVTQVW 195
Query: 199 FQNARAKFRRSLCRQTGVMCGPSAN------QLQMPNVFDDNSLISIDKNGN 336
FQN+RA+ ++ + + P + LQ+ F +N+ + NG+
Sbjct: 196 FQNSRARQKKHIHAGKNKIREPEGSSFARHINLQLTYSFQNNAQNPMHLNGS 247
>sp|O88706|LHX6_MOUSE LIM/homeobox protein Lhx6
Length = 361
Score = 71.6 bits (174), Expect = 3e-12
Identities = 36/93 (38%), Positives = 59/93 (63%)
Frame = +1
Query: 28 SKKGSNNLRQKRVRTSFKHQQLRTMKAYFSMNHNPDSKDLRQLSQKTGLSKRVLQVWFQN 207
S++ S KR RTSF +QL+ M+A F+ ++NPD++ L++L+ TGLS+RV+QVWFQN
Sbjct: 228 SEQDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQN 287
Query: 208 ARAKFRRSLCRQTGVMCGPSANQLQMPNVFDDN 306
RA+ ++ + GP ++P+ D+
Sbjct: 288 CRARHKKHTPQHPVRPLGPPT---RLPSALSDD 317
>sp|O35652|LHX8_MOUSE LIM/homeobox protein Lhx8 (LIM homeodomain Lhx7) (L3)
Length = 367
Score = 71.2 bits (173), Expect = 3e-12
Identities = 30/57 (52%), Positives = 47/57 (82%)
Frame = +1
Query: 58 KRVRTSFKHQQLRTMKAYFSMNHNPDSKDLRQLSQKTGLSKRVLQVWFQNARAKFRR 228
KR RTSF QL+ M+A F+ ++NPD++ L++L+++TGLS+RV+QVWFQN RA+ ++
Sbjct: 247 KRARTSFTADQLQVMQAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRARHKK 303
>sp|Q9UPM6|LHX61_HUMAN LIM/homeobox protein Lhx6.1 (Lhx6)
Length = 363
Score = 70.9 bits (172), Expect = 4e-12
Identities = 32/67 (47%), Positives = 50/67 (74%)
Frame = +1
Query: 28 SKKGSNNLRQKRVRTSFKHQQLRTMKAYFSMNHNPDSKDLRQLSQKTGLSKRVLQVWFQN 207
S++ S KR RTSF +QL+ M+A F+ ++NPD++ L++L+ TGLS+RV+QVWFQN
Sbjct: 210 SEQDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQN 269
Query: 208 ARAKFRR 228
RA+ ++
Sbjct: 270 CRARHKK 276
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,090,203
Number of Sequences: 369166
Number of extensions: 1917407
Number of successful extensions: 6740
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5766
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6652
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8438301375
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)