Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_021_G06 (848 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P61589|RHOA_RAT Transforming protein RhoA >gi|13633865|s... 310 3e-84 sp|P61586|RHOA_HUMAN Transforming protein RhoA (H12) >gi|47... 310 4e-84 sp|P01122|RHO_APLCA RAS-like GTP-binding protein RHO 308 1e-83 sp|P24406|RHOA_CANFA Transforming protein RhoA (Rho1) 307 2e-83 sp|P48148|RHO1_DROME Ras-like GTP-binding protein Rho1 307 2e-83 sp|Q22038|RHOA_CAEEL RAS-like GTP-binding protein RhoA 301 1e-81 sp|P08134|RHOC_HUMAN Rho-related GTP-binding protein RhoC (... 301 2e-81 sp|P62747|RHOB_RAT Rho-related GTP-binding protein RhoB >gi... 295 8e-80 sp|P22122|RHO_DISOM RAS-like GTP-binding protein O-RHO 295 1e-79 sp|Q9C3Y4|RHOA_EMENI Protein rhoA (Rho1 protein homolog) 256 6e-68
>sp|P61589|RHOA_RAT Transforming protein RhoA sp|Q9QUI0|RHOA_MOUSE Transforming protein RhoA Length = 193 Score = 310 bits (794), Expect = 3e-84 Identities = 156/191 (81%), Positives = 167/191 (87%), Gaps = 1/191 (0%) Frame = +3 Query: 36 SIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKSVELALWDTAG 215 +IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD K VELALWDTAG Sbjct: 3 AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAG 62 Query: 216 QEDYDRLRPLSYPDTDVILMCFSIDSIDSLENIPEKWTPEVKHFCQNVPIILVGNKKDLR 395 QEDYDRLRPLSYPDTDVILMCFSIDS DSLENIPEKWTPEVKHFC NVPIILVGNKKDLR Sbjct: 63 QEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLR 122 Query: 396 NEESSRKD-GKNKVEIVKFEDGKAMAERIGAFAYIECSAKTKDGVREVFETATKAALQSX 572 N+E +R++ K K E VK E+G+ MA RIGAF Y+ECSAKTKDGVREVFE AT+AALQ+ Sbjct: 123 NDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQAR 182 Query: 573 XXXXGFKCELL 605 C +L Sbjct: 183 RGKKKSGCLIL 193
>sp|P61586|RHOA_HUMAN Transforming protein RhoA (H12) sp|P61585|RHOA_BOVIN Transforming protein RhoA (Gb) (p21) Length = 193 Score = 310 bits (793), Expect = 4e-84 Identities = 154/179 (86%), Positives = 164/179 (91%), Gaps = 1/179 (0%) Frame = +3 Query: 36 SIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKSVELALWDTAG 215 +IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD K VELALWDTAG Sbjct: 3 AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAG 62 Query: 216 QEDYDRLRPLSYPDTDVILMCFSIDSIDSLENIPEKWTPEVKHFCQNVPIILVGNKKDLR 395 QEDYDRLRPLSYPDTDVILMCFSIDS DSLENIPEKWTPEVKHFC NVPIILVGNKKDLR Sbjct: 63 QEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLR 122 Query: 396 NEESSRKD-GKNKVEIVKFEDGKAMAERIGAFAYIECSAKTKDGVREVFETATKAALQS 569 N+E +R++ K K E VK E+G+ MA RIGAF Y+ECSAKTKDGVREVFE AT+AALQ+ Sbjct: 123 NDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQA 181
>sp|P01122|RHO_APLCA RAS-like GTP-binding protein RHO Length = 192 Score = 308 bits (789), Expect = 1e-83 Identities = 151/178 (84%), Positives = 167/178 (93%), Gaps = 1/178 (0%) Frame = +3 Query: 36 SIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKSVELALWDTAG 215 +IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD K VELALWDTAG Sbjct: 3 AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAG 62 Query: 216 QEDYDRLRPLSYPDTDVILMCFSIDSIDSLENIPEKWTPEVKHFCQNVPIILVGNKKDLR 395 QEDYDRLRPLSYPDTDVILMCFSIDS DSLENIPEKWTPEV+HFC NVPIILVGNKKDLR Sbjct: 63 QEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPNVPIILVGNKKDLR 122 Query: 396 NEESSRKD-GKNKVEIVKFEDGKAMAERIGAFAYIECSAKTKDGVREVFETATKAALQ 566 N+ES++++ K K E V+ EDG+AMAE+I A++Y+ECSAKTK+GVR+VFETAT+AALQ Sbjct: 123 NDESTKRELMKMKQEPVRPEDGRAMAEKINAYSYLECSAKTKEGVRDVFETATRAALQ 180
>sp|P24406|RHOA_CANFA Transforming protein RhoA (Rho1) Length = 193 Score = 307 bits (787), Expect = 2e-83 Identities = 153/179 (85%), Positives = 163/179 (91%), Gaps = 1/179 (0%) Frame = +3 Query: 36 SIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKSVELALWDTAG 215 +IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD K VELALWDTAG Sbjct: 3 AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAG 62 Query: 216 QEDYDRLRPLSYPDTDVILMCFSIDSIDSLENIPEKWTPEVKHFCQNVPIILVGNKKDLR 395 QEDYDRLRPLSYPDTDVILMCFSIDS DSLENIPEKWTPEVKHFC NVPIILVGNKKDLR Sbjct: 63 QEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLR 122 Query: 396 NEESSRKD-GKNKVEIVKFEDGKAMAERIGAFAYIECSAKTKDGVREVFETATKAALQS 569 N+E +R++ K K E VK +G+ MA RIGAF Y+ECSAKTKDGVREVFE AT+AALQ+ Sbjct: 123 NDEHTRRELAKMKQEPVKPTEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQA 181
>sp|P48148|RHO1_DROME Ras-like GTP-binding protein Rho1 Length = 192 Score = 307 bits (787), Expect = 2e-83 Identities = 151/179 (84%), Positives = 166/179 (92%), Gaps = 1/179 (0%) Frame = +3 Query: 33 TSIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKSVELALWDTA 212 T+IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD K VELALWDTA Sbjct: 2 TTIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTA 61 Query: 213 GQEDYDRLRPLSYPDTDVILMCFSIDSIDSLENIPEKWTPEVKHFCQNVPIILVGNKKDL 392 GQEDYDRLRPLSYPDTDVILMCFS+DS DSLENIPEKWTPEVKHFC NVPIILVGNKKDL Sbjct: 62 GQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDL 121 Query: 393 RNEESSRKD-GKNKVEIVKFEDGKAMAERIGAFAYIECSAKTKDGVREVFETATKAALQ 566 RN+ ++ +D K K E VK ++G+AMAE+I AFAY+ECSAK+K+GVR+VFETAT+AALQ Sbjct: 122 RNDPNTIRDLAKMKQEPVKPQEGRAMAEKINAFAYLECSAKSKEGVRDVFETATRAALQ 180
>sp|Q22038|RHOA_CAEEL RAS-like GTP-binding protein RhoA Length = 192 Score = 301 bits (772), Expect = 1e-81 Identities = 152/191 (79%), Positives = 168/191 (87%), Gaps = 1/191 (0%) Frame = +3 Query: 36 SIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKSVELALWDTAG 215 +IRKKLVIVGDGACGKTCLLIVFSKDQFP+VYVPTVFENYVADIEVD K VELALWDTAG Sbjct: 3 AIRKKLVIVGDGACGKTCLLIVFSKDQFPDVYVPTVFENYVADIEVDGKQVELALWDTAG 62 Query: 216 QEDYDRLRPLSYPDTDVILMCFSIDSIDSLENIPEKWTPEVKHFCQNVPIILVGNKKDLR 395 QEDYDRLRPLSYPDTDVILMCFSIDS DSLENIPEKWTPEV+HFC NVPIILVGNK+DLR Sbjct: 63 QEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPNVPIILVGNKRDLR 122 Query: 396 NE-ESSRKDGKNKVEIVKFEDGKAMAERIGAFAYIECSAKTKDGVREVFETATKAALQSX 572 ++ ++ R+ K K E VK E G+A+AE+IGAFAY+ECSAKTKDG+REVFE AT+AALQ Sbjct: 123 SDPQTVRELAKMKQEPVKPEQGRAIAEQIGAFAYLECSAKTKDGIREVFEKATQAALQQK 182 Query: 573 XXXXGFKCELL 605 KC +L Sbjct: 183 KKKKS-KCMIL 192
>sp|P08134|RHOC_HUMAN Rho-related GTP-binding protein RhoC (H9) sp|Q62159|RHOC_MOUSE Rho-related GTP-binding protein RhoC (Silica-induced gene 61 protein) (SIG-61) Length = 193 Score = 301 bits (771), Expect = 2e-81 Identities = 148/178 (83%), Positives = 160/178 (89%), Gaps = 1/178 (0%) Frame = +3 Query: 36 SIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKSVELALWDTAG 215 +IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY+ADIEVD K VELALWDTAG Sbjct: 3 AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAG 62 Query: 216 QEDYDRLRPLSYPDTDVILMCFSIDSIDSLENIPEKWTPEVKHFCQNVPIILVGNKKDLR 395 QEDYDRLRPLSYPDTDVILMCFSIDS DSLENIPEKWTPEVKHFC NVPIILVGNKKDLR Sbjct: 63 QEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLR 122 Query: 396 NEESSRKD-GKNKVEIVKFEDGKAMAERIGAFAYIECSAKTKDGVREVFETATKAALQ 566 +E +R++ K K E V+ E+G+ MA RI AF Y+ECSAKTK+GVREVFE AT+A LQ Sbjct: 123 QDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ 180
>sp|P62747|RHOB_RAT Rho-related GTP-binding protein RhoB sp|P62746|RHOB_MOUSE Rho-related GTP-binding protein RhoB sp|P62745|RHOB_HUMAN Rho-related GTP-binding protein RhoB (H6) Length = 196 Score = 295 bits (756), Expect = 8e-80 Identities = 145/178 (81%), Positives = 160/178 (89%), Gaps = 1/178 (0%) Frame = +3 Query: 36 SIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKSVELALWDTAG 215 +IRKKLV+VGDGACGKTCLLIVFSKD+FPEVYVPTVFENYVADIEVD K VELALWDTAG Sbjct: 3 AIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDTAG 62 Query: 216 QEDYDRLRPLSYPDTDVILMCFSIDSIDSLENIPEKWTPEVKHFCQNVPIILVGNKKDLR 395 QEDYDRLRPLSYPDTDVILMCFS+DS DSLENIPEKW PEVKHFC NVPIILV NKKDLR Sbjct: 63 QEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKDLR 122 Query: 396 NEESSRKD-GKNKVEIVKFEDGKAMAERIGAFAYIECSAKTKDGVREVFETATKAALQ 566 ++E R + + K E V+ +DG+AMA RI A+ Y+ECSAKTK+GVREVFETAT+AALQ Sbjct: 123 SDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ 180
>sp|P22122|RHO_DISOM RAS-like GTP-binding protein O-RHO Length = 192 Score = 295 bits (755), Expect = 1e-79 Identities = 148/190 (77%), Positives = 159/190 (83%) Frame = +3 Query: 36 SIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKSVELALWDTAG 215 +IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD K VELALWDTAG Sbjct: 3 AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAG 62 Query: 216 QEDYDRLRPLSYPDTDVILMCFSIDSIDSLENIPEKWTPEVKHFCQNVPIILVGNKKDLR 395 QEDYDRLRPLSYPDTDVILMCFSIDS DSLENIPEKWTPEVKHFC N+PIILVGNKK Sbjct: 63 QEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNIPIILVGNKKTAG 122 Query: 396 NEESSRKDGKNKVEIVKFEDGKAMAERIGAFAYIECSAKTKDGVREVFETATKAALQSXX 575 +E + R+ K K E VK +D K M RI AF Y+ECSAKTK+GVREVFE A++AALQ+ Sbjct: 123 DEHTRRELAKMKQEPVKPDDAKEMGSRIKAFGYLECSAKTKEGVREVFELASRAALQAKK 182 Query: 576 XXXGFKCELL 605 C LL Sbjct: 183 TKSKSPCLLL 192
>sp|Q9C3Y4|RHOA_EMENI Protein rhoA (Rho1 protein homolog) Length = 193 Score = 256 bits (654), Expect = 6e-68 Identities = 126/190 (66%), Positives = 152/190 (80%), Gaps = 1/190 (0%) Frame = +3 Query: 39 IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKSVELALWDTAGQ 218 IR+KLVIVGDGACGKTCLLIVFSK FPEVYVPTVFENYVAD+EVD K VELALWDTAGQ Sbjct: 4 IRRKLVIVGDGACGKTCLLIVFSKGTFPEVYVPTVFENYVADVEVDGKHVELALWDTAGQ 63 Query: 219 EDYDRLRPLSYPDTDVILMCFSIDSIDSLENIPEKWTPEVKHFCQNVPIILVGNKKDLRN 398 EDYDRLRPLSYPD+ VIL+CF++DS DSL+N+ EKW EV HFCQ +PIILVG KKDLR+ Sbjct: 64 EDYDRLRPLSYPDSHVILICFAVDSPDSLDNVQEKWISEVLHFCQGLPIILVGCKKDLRH 123 Query: 399 EESSRKD-GKNKVEIVKFEDGKAMAERIGAFAYIECSAKTKDGVREVFETATKAALQSXX 575 + + ++ K + V E G+ + ++IGA+ Y+ECSA+T +GVREVFE AT+AAL + Sbjct: 124 DPKTIEELNKTSQKPVTPEQGEEVRKKIGAYKYLECSARTNEGVREVFEAATRAALLTKT 183 Query: 576 XXXGFKCELL 605 KC +L Sbjct: 184 HKSKKKCSIL 193
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 83,694,156 Number of Sequences: 369166 Number of extensions: 1513470 Number of successful extensions: 6052 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5240 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5380 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 8341863645 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)