Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_021_G06
(848 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P61589|RHOA_RAT Transforming protein RhoA >gi|13633865|s... 310 3e-84
sp|P61586|RHOA_HUMAN Transforming protein RhoA (H12) >gi|47... 310 4e-84
sp|P01122|RHO_APLCA RAS-like GTP-binding protein RHO 308 1e-83
sp|P24406|RHOA_CANFA Transforming protein RhoA (Rho1) 307 2e-83
sp|P48148|RHO1_DROME Ras-like GTP-binding protein Rho1 307 2e-83
sp|Q22038|RHOA_CAEEL RAS-like GTP-binding protein RhoA 301 1e-81
sp|P08134|RHOC_HUMAN Rho-related GTP-binding protein RhoC (... 301 2e-81
sp|P62747|RHOB_RAT Rho-related GTP-binding protein RhoB >gi... 295 8e-80
sp|P22122|RHO_DISOM RAS-like GTP-binding protein O-RHO 295 1e-79
sp|Q9C3Y4|RHOA_EMENI Protein rhoA (Rho1 protein homolog) 256 6e-68
>sp|P61589|RHOA_RAT Transforming protein RhoA
sp|Q9QUI0|RHOA_MOUSE Transforming protein RhoA
Length = 193
Score = 310 bits (794), Expect = 3e-84
Identities = 156/191 (81%), Positives = 167/191 (87%), Gaps = 1/191 (0%)
Frame = +3
Query: 36 SIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKSVELALWDTAG 215
+IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD K VELALWDTAG
Sbjct: 3 AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAG 62
Query: 216 QEDYDRLRPLSYPDTDVILMCFSIDSIDSLENIPEKWTPEVKHFCQNVPIILVGNKKDLR 395
QEDYDRLRPLSYPDTDVILMCFSIDS DSLENIPEKWTPEVKHFC NVPIILVGNKKDLR
Sbjct: 63 QEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLR 122
Query: 396 NEESSRKD-GKNKVEIVKFEDGKAMAERIGAFAYIECSAKTKDGVREVFETATKAALQSX 572
N+E +R++ K K E VK E+G+ MA RIGAF Y+ECSAKTKDGVREVFE AT+AALQ+
Sbjct: 123 NDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQAR 182
Query: 573 XXXXGFKCELL 605
C +L
Sbjct: 183 RGKKKSGCLIL 193
>sp|P61586|RHOA_HUMAN Transforming protein RhoA (H12)
sp|P61585|RHOA_BOVIN Transforming protein RhoA (Gb) (p21)
Length = 193
Score = 310 bits (793), Expect = 4e-84
Identities = 154/179 (86%), Positives = 164/179 (91%), Gaps = 1/179 (0%)
Frame = +3
Query: 36 SIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKSVELALWDTAG 215
+IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD K VELALWDTAG
Sbjct: 3 AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAG 62
Query: 216 QEDYDRLRPLSYPDTDVILMCFSIDSIDSLENIPEKWTPEVKHFCQNVPIILVGNKKDLR 395
QEDYDRLRPLSYPDTDVILMCFSIDS DSLENIPEKWTPEVKHFC NVPIILVGNKKDLR
Sbjct: 63 QEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLR 122
Query: 396 NEESSRKD-GKNKVEIVKFEDGKAMAERIGAFAYIECSAKTKDGVREVFETATKAALQS 569
N+E +R++ K K E VK E+G+ MA RIGAF Y+ECSAKTKDGVREVFE AT+AALQ+
Sbjct: 123 NDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQA 181
>sp|P01122|RHO_APLCA RAS-like GTP-binding protein RHO
Length = 192
Score = 308 bits (789), Expect = 1e-83
Identities = 151/178 (84%), Positives = 167/178 (93%), Gaps = 1/178 (0%)
Frame = +3
Query: 36 SIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKSVELALWDTAG 215
+IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD K VELALWDTAG
Sbjct: 3 AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAG 62
Query: 216 QEDYDRLRPLSYPDTDVILMCFSIDSIDSLENIPEKWTPEVKHFCQNVPIILVGNKKDLR 395
QEDYDRLRPLSYPDTDVILMCFSIDS DSLENIPEKWTPEV+HFC NVPIILVGNKKDLR
Sbjct: 63 QEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPNVPIILVGNKKDLR 122
Query: 396 NEESSRKD-GKNKVEIVKFEDGKAMAERIGAFAYIECSAKTKDGVREVFETATKAALQ 566
N+ES++++ K K E V+ EDG+AMAE+I A++Y+ECSAKTK+GVR+VFETAT+AALQ
Sbjct: 123 NDESTKRELMKMKQEPVRPEDGRAMAEKINAYSYLECSAKTKEGVRDVFETATRAALQ 180
>sp|P24406|RHOA_CANFA Transforming protein RhoA (Rho1)
Length = 193
Score = 307 bits (787), Expect = 2e-83
Identities = 153/179 (85%), Positives = 163/179 (91%), Gaps = 1/179 (0%)
Frame = +3
Query: 36 SIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKSVELALWDTAG 215
+IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD K VELALWDTAG
Sbjct: 3 AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAG 62
Query: 216 QEDYDRLRPLSYPDTDVILMCFSIDSIDSLENIPEKWTPEVKHFCQNVPIILVGNKKDLR 395
QEDYDRLRPLSYPDTDVILMCFSIDS DSLENIPEKWTPEVKHFC NVPIILVGNKKDLR
Sbjct: 63 QEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLR 122
Query: 396 NEESSRKD-GKNKVEIVKFEDGKAMAERIGAFAYIECSAKTKDGVREVFETATKAALQS 569
N+E +R++ K K E VK +G+ MA RIGAF Y+ECSAKTKDGVREVFE AT+AALQ+
Sbjct: 123 NDEHTRRELAKMKQEPVKPTEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQA 181
>sp|P48148|RHO1_DROME Ras-like GTP-binding protein Rho1
Length = 192
Score = 307 bits (787), Expect = 2e-83
Identities = 151/179 (84%), Positives = 166/179 (92%), Gaps = 1/179 (0%)
Frame = +3
Query: 33 TSIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKSVELALWDTA 212
T+IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD K VELALWDTA
Sbjct: 2 TTIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTA 61
Query: 213 GQEDYDRLRPLSYPDTDVILMCFSIDSIDSLENIPEKWTPEVKHFCQNVPIILVGNKKDL 392
GQEDYDRLRPLSYPDTDVILMCFS+DS DSLENIPEKWTPEVKHFC NVPIILVGNKKDL
Sbjct: 62 GQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDL 121
Query: 393 RNEESSRKD-GKNKVEIVKFEDGKAMAERIGAFAYIECSAKTKDGVREVFETATKAALQ 566
RN+ ++ +D K K E VK ++G+AMAE+I AFAY+ECSAK+K+GVR+VFETAT+AALQ
Sbjct: 122 RNDPNTIRDLAKMKQEPVKPQEGRAMAEKINAFAYLECSAKSKEGVRDVFETATRAALQ 180
>sp|Q22038|RHOA_CAEEL RAS-like GTP-binding protein RhoA
Length = 192
Score = 301 bits (772), Expect = 1e-81
Identities = 152/191 (79%), Positives = 168/191 (87%), Gaps = 1/191 (0%)
Frame = +3
Query: 36 SIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKSVELALWDTAG 215
+IRKKLVIVGDGACGKTCLLIVFSKDQFP+VYVPTVFENYVADIEVD K VELALWDTAG
Sbjct: 3 AIRKKLVIVGDGACGKTCLLIVFSKDQFPDVYVPTVFENYVADIEVDGKQVELALWDTAG 62
Query: 216 QEDYDRLRPLSYPDTDVILMCFSIDSIDSLENIPEKWTPEVKHFCQNVPIILVGNKKDLR 395
QEDYDRLRPLSYPDTDVILMCFSIDS DSLENIPEKWTPEV+HFC NVPIILVGNK+DLR
Sbjct: 63 QEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPNVPIILVGNKRDLR 122
Query: 396 NE-ESSRKDGKNKVEIVKFEDGKAMAERIGAFAYIECSAKTKDGVREVFETATKAALQSX 572
++ ++ R+ K K E VK E G+A+AE+IGAFAY+ECSAKTKDG+REVFE AT+AALQ
Sbjct: 123 SDPQTVRELAKMKQEPVKPEQGRAIAEQIGAFAYLECSAKTKDGIREVFEKATQAALQQK 182
Query: 573 XXXXGFKCELL 605
KC +L
Sbjct: 183 KKKKS-KCMIL 192
>sp|P08134|RHOC_HUMAN Rho-related GTP-binding protein RhoC (H9)
sp|Q62159|RHOC_MOUSE Rho-related GTP-binding protein RhoC (Silica-induced gene 61
protein) (SIG-61)
Length = 193
Score = 301 bits (771), Expect = 2e-81
Identities = 148/178 (83%), Positives = 160/178 (89%), Gaps = 1/178 (0%)
Frame = +3
Query: 36 SIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKSVELALWDTAG 215
+IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY+ADIEVD K VELALWDTAG
Sbjct: 3 AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAG 62
Query: 216 QEDYDRLRPLSYPDTDVILMCFSIDSIDSLENIPEKWTPEVKHFCQNVPIILVGNKKDLR 395
QEDYDRLRPLSYPDTDVILMCFSIDS DSLENIPEKWTPEVKHFC NVPIILVGNKKDLR
Sbjct: 63 QEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLR 122
Query: 396 NEESSRKD-GKNKVEIVKFEDGKAMAERIGAFAYIECSAKTKDGVREVFETATKAALQ 566
+E +R++ K K E V+ E+G+ MA RI AF Y+ECSAKTK+GVREVFE AT+A LQ
Sbjct: 123 QDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ 180
>sp|P62747|RHOB_RAT Rho-related GTP-binding protein RhoB
sp|P62746|RHOB_MOUSE Rho-related GTP-binding protein RhoB
sp|P62745|RHOB_HUMAN Rho-related GTP-binding protein RhoB (H6)
Length = 196
Score = 295 bits (756), Expect = 8e-80
Identities = 145/178 (81%), Positives = 160/178 (89%), Gaps = 1/178 (0%)
Frame = +3
Query: 36 SIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKSVELALWDTAG 215
+IRKKLV+VGDGACGKTCLLIVFSKD+FPEVYVPTVFENYVADIEVD K VELALWDTAG
Sbjct: 3 AIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDTAG 62
Query: 216 QEDYDRLRPLSYPDTDVILMCFSIDSIDSLENIPEKWTPEVKHFCQNVPIILVGNKKDLR 395
QEDYDRLRPLSYPDTDVILMCFS+DS DSLENIPEKW PEVKHFC NVPIILV NKKDLR
Sbjct: 63 QEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKDLR 122
Query: 396 NEESSRKD-GKNKVEIVKFEDGKAMAERIGAFAYIECSAKTKDGVREVFETATKAALQ 566
++E R + + K E V+ +DG+AMA RI A+ Y+ECSAKTK+GVREVFETAT+AALQ
Sbjct: 123 SDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ 180
>sp|P22122|RHO_DISOM RAS-like GTP-binding protein O-RHO
Length = 192
Score = 295 bits (755), Expect = 1e-79
Identities = 148/190 (77%), Positives = 159/190 (83%)
Frame = +3
Query: 36 SIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKSVELALWDTAG 215
+IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD K VELALWDTAG
Sbjct: 3 AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAG 62
Query: 216 QEDYDRLRPLSYPDTDVILMCFSIDSIDSLENIPEKWTPEVKHFCQNVPIILVGNKKDLR 395
QEDYDRLRPLSYPDTDVILMCFSIDS DSLENIPEKWTPEVKHFC N+PIILVGNKK
Sbjct: 63 QEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNIPIILVGNKKTAG 122
Query: 396 NEESSRKDGKNKVEIVKFEDGKAMAERIGAFAYIECSAKTKDGVREVFETATKAALQSXX 575
+E + R+ K K E VK +D K M RI AF Y+ECSAKTK+GVREVFE A++AALQ+
Sbjct: 123 DEHTRRELAKMKQEPVKPDDAKEMGSRIKAFGYLECSAKTKEGVREVFELASRAALQAKK 182
Query: 576 XXXGFKCELL 605
C LL
Sbjct: 183 TKSKSPCLLL 192
>sp|Q9C3Y4|RHOA_EMENI Protein rhoA (Rho1 protein homolog)
Length = 193
Score = 256 bits (654), Expect = 6e-68
Identities = 126/190 (66%), Positives = 152/190 (80%), Gaps = 1/190 (0%)
Frame = +3
Query: 39 IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKSVELALWDTAGQ 218
IR+KLVIVGDGACGKTCLLIVFSK FPEVYVPTVFENYVAD+EVD K VELALWDTAGQ
Sbjct: 4 IRRKLVIVGDGACGKTCLLIVFSKGTFPEVYVPTVFENYVADVEVDGKHVELALWDTAGQ 63
Query: 219 EDYDRLRPLSYPDTDVILMCFSIDSIDSLENIPEKWTPEVKHFCQNVPIILVGNKKDLRN 398
EDYDRLRPLSYPD+ VIL+CF++DS DSL+N+ EKW EV HFCQ +PIILVG KKDLR+
Sbjct: 64 EDYDRLRPLSYPDSHVILICFAVDSPDSLDNVQEKWISEVLHFCQGLPIILVGCKKDLRH 123
Query: 399 EESSRKD-GKNKVEIVKFEDGKAMAERIGAFAYIECSAKTKDGVREVFETATKAALQSXX 575
+ + ++ K + V E G+ + ++IGA+ Y+ECSA+T +GVREVFE AT+AAL +
Sbjct: 124 DPKTIEELNKTSQKPVTPEQGEEVRKKIGAYKYLECSARTNEGVREVFEAATRAALLTKT 183
Query: 576 XXXGFKCELL 605
KC +L
Sbjct: 184 HKSKKKCSIL 193
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 83,694,156
Number of Sequences: 369166
Number of extensions: 1513470
Number of successful extensions: 6052
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5240
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5380
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8341863645
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)