Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_021_F14
(561 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q66S03|NATTE_THANI Nattectin precursor 44 3e-04
sp|P98110|LYAM2_PIG E-selectin precursor (Endothelial leuko... 44 4e-04
sp|P27113|LYAM2_RABIT E-selectin precursor (Endothelial leu... 42 0.001
sp|P22897|MANR1_HUMAN Macrophage mannose receptor precursor... 40 0.003
sp|P33730|LYAM2_CANFA E-selectin precursor (Endothelial leu... 40 0.003
sp|P16581|LYAM2_HUMAN E-selectin precursor (Endothelial leu... 40 0.004
sp|P98105|LYAM2_RAT E-selectin precursor (Endothelial leuko... 40 0.004
sp|P81397|RHCA_AGKRH Rhodocetin alpha subunit 39 0.007
sp|Q95LG1|LYAM2_HORSE E-selectin precursor (Endothelial leu... 39 0.011
sp|P49260|PLA2R_RABIT 180 kDa secretory phospholipase A2 re... 38 0.015
>sp|Q66S03|NATTE_THANI Nattectin precursor
Length = 159
Score = 43.9 bits (102), Expect = 3e-04
Identities = 39/138 (28%), Positives = 56/138 (40%), Gaps = 2/138 (1%)
Frame = +1
Query: 4 GDKMFAFVHGDIDARMNFTDAEEFCSNFSLHRNNSDSHLASIQNQTEVNLIQNWILNL-- 177
G + F F G +D + AE C +LASI N+ E N I + I L
Sbjct: 39 GSRCFTFHRGSMD----WASAEAACIR-------KGGNLASIHNRREQNFITHLIHKLSG 87
Query: 178 EKKSFWIGGEIICSMNALLDRMFLLHWISNDKVEFTNFKVPNYNVKNMKVTEKRCVSVDH 357
E + WIGG +A+ + M W +D +F N+K + V + C +
Sbjct: 88 ENRRTWIGGN-----DAVKEGM----WFWSDGSKF-NYKGWKKGQPDKHVPAEHCAETNF 137
Query: 358 KNGMWGVHHCSEKKFFLC 411
K W C K+ FLC
Sbjct: 138 KGAFWNNALCKVKRSFLC 155
>sp|P98110|LYAM2_PIG E-selectin precursor (Endothelial leukocyte adhesion molecule 1)
(ELAM-1) (Leukocyte-endothelial cell adhesion molecule
2) (LECAM2)
Length = 484
Score = 43.5 bits (101), Expect = 4e-04
Identities = 38/130 (29%), Positives = 51/130 (39%), Gaps = 7/130 (5%)
Frame = +1
Query: 49 MNFTDAEEFCSNFSLHRNNSDSHLASIQNQTEVNLIQNWILNLEKKSFWIGGEIICSMNA 228
M F DA +C +HL +IQN E+ + N N +WIG I +N
Sbjct: 32 MTFDDASAYCQQ-------RYTHLVAIQNHAEIEYL-NSTFNYSASYYWIG---IRKING 80
Query: 229 LLDRMFLLHWISNDKV---EFTNFKVPNYNVKNMKVTEKRCVSV----DHKNGMWGVHHC 387
WI K E TN+ N K + + CV + D +G W C
Sbjct: 81 TWT------WIGTKKALTPEATNWAPGE---PNNKQSNEDCVEIYIKRDKDSGKWNDERC 131
Query: 388 SEKKFFLCLT 417
S+KK LC T
Sbjct: 132 SKKKLALCYT 141
>sp|P27113|LYAM2_RABIT E-selectin precursor (Endothelial leukocyte adhesion molecule 1)
(ELAM-1) (Leukocyte-endothelial cell adhesion molecule
2) (LECAM2)
Length = 551
Score = 41.6 bits (96), Expect = 0.001
Identities = 35/127 (27%), Positives = 53/127 (41%), Gaps = 4/127 (3%)
Frame = +1
Query: 49 MNFTDAEEFCSNFSLHRNNSDSHLASIQNQTEVNLIQNWILNLEKKSFWIGGEIICSMNA 228
M + +A +C + +HL +IQN+ E++ + N IL+ +WIG I +N
Sbjct: 33 MTYDEASAYCQQ-------NYTHLVAIQNKEEIDYL-NSILDYSPSYYWIG---IRKVNN 81
Query: 229 LLDRMFLLHWISNDKVEFTNFKVPNYNVKNMKVTEKRCVSVDHKN----GMWGVHHCSEK 396
+ W+ K K N K + CV + K GMW CS+K
Sbjct: 82 VWI------WVGTHKPLTEGAKNWAPGEPNNKQNNEDCVEIYIKRPKDTGMWNDERCSKK 135
Query: 397 KFFLCLT 417
K LC T
Sbjct: 136 KLALCYT 142
>sp|P22897|MANR1_HUMAN Macrophage mannose receptor precursor (MMR) (CD206 antigen)
Length = 1456
Score = 40.4 bits (93), Expect = 0.003
Identities = 28/131 (21%), Positives = 56/131 (42%)
Frame = +1
Query: 40 DARMNFTDAEEFCSNFSLHRNNSDSHLASIQNQTEVNLIQNWILNLEKKSFWIGGEIICS 219
D + F+ +E N + L SIQ+++E + ++ + +S + G +I
Sbjct: 809 DYQYYFSKEKETMDNARAFCKRNFGDLVSIQSESEKKFLWKYVNRNDAQSAYFIGLLIS- 867
Query: 220 MNALLDRMFLLHWISNDKVEFTNFKVPNYNVKNMKVTEKRCVSVDHKNGMWGVHHCSEKK 399
LD+ F W+ KV++ ++ N N ++ CV++ +G W +C
Sbjct: 868 ----LDKKFA--WMDGSKVDYVSWATGEPNFAN---EDENCVTMYSNSGFWNDINCGYPN 918
Query: 400 FFLCLTKNQLV 432
F+C N +
Sbjct: 919 AFICQRHNSSI 929
Score = 39.7 bits (91), Expect = 0.005
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 1/101 (0%)
Frame = +1
Query: 112 SHLASIQNQTEVNLIQNWILNLEKKS-FWIGGEIICSMNALLDRMFLLHWISNDKVEFTN 288
S L SI++ E + + + L+ K+ FWIG + ++ +L WI+N V F N
Sbjct: 1268 SSLVSIESAAESSFLSYRVEPLKSKTNFWIG------LFRNVEGTWL--WINNSPVSFVN 1319
Query: 289 FKVPNYNVKNMKVTEKRCVSVDHKNGMWGVHHCSEKKFFLC 411
+N + CV++ +G W HCS K ++C
Sbjct: 1320 -----WNTGDPSGERNDCVALHASSGFWSNIHCSSYKGYIC 1355
Score = 37.4 bits (85), Expect = 0.026
Identities = 28/121 (23%), Positives = 53/121 (43%), Gaps = 2/121 (1%)
Frame = +1
Query: 55 FTDAEEFCSNFSLHRNNSDSHLASIQNQTEVNLIQNWILNLEKKSFWIGGEIICSMNALL 234
F +A + C NN +++L +I+++ E + +++ +K FW G I +
Sbjct: 525 FAEANQTC-------NNENAYLTTIEDRYEQAFLTSFVGLRPEKYFWTGLSDIQTKGT-- 575
Query: 235 DRMFLLHWISNDKVEFTNFKVPNYNVKNMKVTEKRCVSV--DHKNGMWGVHHCSEKKFFL 408
W ++V FT++ +M + CV++ G+W V C EK F+
Sbjct: 576 -----FQWTIEEEVRFTHWN------SDMPGRKPGCVAMRTGIAGGLWDVLKCDEKAKFV 624
Query: 409 C 411
C
Sbjct: 625 C 625
Score = 33.5 bits (75), Expect = 0.37
Identities = 29/123 (23%), Positives = 50/123 (40%), Gaps = 6/123 (4%)
Frame = +1
Query: 79 SNFSLHRNNSDSHLASIQNQTEVNLIQNWILNLEKKSFWIGGEI------ICSMNALLDR 240
S++SL R H A + +LI + + W+ E I + L D
Sbjct: 1105 SSYSLMRQKFQWHEAETYCKLHNSLIASILDPYSNAFAWLQMETSNERVWIALNSNLTDN 1164
Query: 241 MFLLHWISNDKVEFTNFKVPNYNVKNMKVTEKRCVSVDHKNGMWGVHHCSEKKFFLCLTK 420
+ W +V +TN+ +K+ CV +D +G W HC+E +FLC
Sbjct: 1165 QYT--WTDKWRVRYTNWAADEPKLKSA------CVYLD-LDGYWKTAHCNESFYFLCKRS 1215
Query: 421 NQL 429
+++
Sbjct: 1216 DEI 1218
>sp|P33730|LYAM2_CANFA E-selectin precursor (Endothelial leukocyte adhesion molecule 1)
(ELAM-1) (Leukocyte-endothelial cell adhesion molecule
2) (LECAM2)
Length = 611
Score = 40.4 bits (93), Expect = 0.003
Identities = 34/127 (26%), Positives = 49/127 (38%), Gaps = 4/127 (3%)
Frame = +1
Query: 49 MNFTDAEEFCSNFSLHRNNSDSHLASIQNQTEVNLIQNWILNLEKKSFWIGGEIICSMNA 228
M F +A +C +HL +IQNQ E+ + N + +WIG I +N
Sbjct: 32 MTFDEASTYCQQ-------RYTHLVAIQNQEEIKYL-NSMFTYTPTYYWIG---IRKVNK 80
Query: 229 LLDRMFLLHWISNDKVEFTNFKVPNYNVKNMKVTEKRCVSV----DHKNGMWGVHHCSEK 396
WI K+ K N K ++ CV + D +G W C +K
Sbjct: 81 KWT------WIGTQKLLTEEAKNWAPGEPNNKQNDEDCVEIYIKRDKDSGKWNDERCDKK 134
Query: 397 KFFLCLT 417
K LC T
Sbjct: 135 KLALCYT 141
>sp|P16581|LYAM2_HUMAN E-selectin precursor (Endothelial leukocyte adhesion molecule 1)
(ELAM-1) (Leukocyte-endothelial cell adhesion molecule
2) (LECAM2) (CD62E antigen)
Length = 610
Score = 40.0 bits (92), Expect = 0.004
Identities = 32/127 (25%), Positives = 51/127 (40%), Gaps = 4/127 (3%)
Frame = +1
Query: 49 MNFTDAEEFCSNFSLHRNNSDSHLASIQNQTEVNLIQNWILNLEKKSFWIGGEIICSMNA 228
M + +A +C +HL +IQN+ E+ + N IL+ +WIG + ++
Sbjct: 31 MTYDEASAYCQQ-------RYTHLVAIQNKEEIEYL-NSILSYSPSYYWIGIRKVNNVWV 82
Query: 229 LLDRMFLLHWISNDKVEFTNFKVPNYNVKNMKVTEKRCVSVDHKN----GMWGVHHCSEK 396
W+ K K N + ++ CV + K GMW CS+K
Sbjct: 83 ---------WVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREKDVGMWNDERCSKK 133
Query: 397 KFFLCLT 417
K LC T
Sbjct: 134 KLALCYT 140
>sp|P98105|LYAM2_RAT E-selectin precursor (Endothelial leukocyte adhesion molecule 1)
(ELAM-1) (Leukocyte-endothelial cell adhesion molecule
2) (LECAM2)
Length = 549
Score = 40.0 bits (92), Expect = 0.004
Identities = 35/140 (25%), Positives = 53/140 (37%), Gaps = 4/140 (2%)
Frame = +1
Query: 10 KMFAFVHGDIDARMNFTDAEEFCSNFSLHRNNSDSHLASIQNQTEVNLIQNWILNLEKKS 189
K A+ + M + +A +C +HL +IQN+ E+N + N L
Sbjct: 18 KSIAWYYNASSELMTYDEASAYCQR-------DYTHLVAIQNKEEINYL-NSTLRYSPSY 69
Query: 190 FWIGGEIICSMNALLDRMFLLHWISNDKVEFTNFKVPNYNVKNMKVTEKRCVSV----DH 357
+WIG I +N + W+ K K N K + CV +
Sbjct: 70 YWIG---IRKVNNVWI------WVGTQKPLTEEAKNWAPGEPNNKQRNEDCVEIYIQRPK 120
Query: 358 KNGMWGVHHCSEKKFFLCLT 417
+GMW C +KK LC T
Sbjct: 121 DSGMWNDERCDKKKLALCYT 140
>sp|P81397|RHCA_AGKRH Rhodocetin alpha subunit
Length = 133
Score = 39.3 bits (90), Expect = 0.007
Identities = 30/127 (23%), Positives = 53/127 (41%), Gaps = 5/127 (3%)
Frame = +1
Query: 46 RMNFTDAEEFCSNFSLHRNNSDSHLASIQNQTEVNLIQNWILN-LEKKSF--WIGGEIIC 216
+ + +AE FC+ ++HL S++N+ E + + N E K + WIG +I
Sbjct: 20 KKTWEEAERFCTE-----QEKEAHLVSMENRLEAVFVDMVMENNFENKIYRSWIGLKIEN 74
Query: 217 SMNALLDRMFLLHWISNDKVEFTNFKVPNYNVKNMKVTEKRCVSVDHKNGM--WGVHHCS 390
+ L W + + N P ++C +DH++G+ W C
Sbjct: 75 K-----GQRSNLEWSDGSSISYENLYEPYM---------EKCFLMDHQSGLPKWHTADCE 120
Query: 391 EKKFFLC 411
EK F+C
Sbjct: 121 EKNVFMC 127
>sp|Q95LG1|LYAM2_HORSE E-selectin precursor (Endothelial leukocyte adhesion molecule 1)
(ELAM-1) (Leukocyte-endothelial cell adhesion molecule
2) (LECAM2)
Length = 610
Score = 38.5 bits (88), Expect = 0.011
Identities = 36/127 (28%), Positives = 50/127 (39%), Gaps = 4/127 (3%)
Frame = +1
Query: 49 MNFTDAEEFCSNFSLHRNNSDSHLASIQNQTEVNLIQNWILNLEKKSFWIGGEIICSMNA 228
M F +A +C +HL +IQNQ E+ + N I N +WIG +
Sbjct: 31 MTFDEASAYCQQ-------RYTHLVAIQNQEEIKYL-NSIFNHSPSYYWIG------IRK 76
Query: 229 LLDRMFLLHWISNDKVEFTNFKVPNYNVKNMKVTEKRCVSVDHKN----GMWGVHHCSEK 396
+ D+ WI K K N K E CV + K G W +C++K
Sbjct: 77 VNDKWV---WIGTQKPLTEEAKNWAPGEPNNKQNED-CVEIYIKRYKDAGKWNDENCNKK 132
Query: 397 KFFLCLT 417
K LC T
Sbjct: 133 KLALCYT 139
>sp|P49260|PLA2R_RABIT 180 kDa secretory phospholipase A2 receptor precursor (PLA2-R)
Length = 1458
Score = 38.1 bits (87), Expect = 0.015
Identities = 33/127 (25%), Positives = 50/127 (39%), Gaps = 1/127 (0%)
Frame = +1
Query: 67 EEFCSNFSLHRN-NSDSHLASIQNQTEVNLIQNWILNLEKKSFWIGGEIICSMNALLDRM 243
EE N +LH +S+S L I + EV + + N WIG S N
Sbjct: 393 EEKTWNEALHSCLSSNSTLIDIGSLAEVEFLVTLLGNENASETWIG----LSSNTF---P 445
Query: 244 FLLHWISNDKVEFTNFKVPNYNVKNMKVTEKRCVSVDHKNGMWGVHHCSEKKFFLCLTKN 423
W + V FTN+ + + + CVS + G W V C E F++C
Sbjct: 446 VSFEWSNGSSVIFTNWHTLEPQIFPNR--SQLCVSAEQSEGHWKVTDCEETHFYVCKKPG 503
Query: 424 QLVIEKE 444
++ + E
Sbjct: 504 HVLSDAE 510
Score = 32.3 bits (72), Expect = 0.82
Identities = 19/71 (26%), Positives = 29/71 (40%)
Frame = +1
Query: 250 LHWISNDKVEFTNFKVPNYNVKNMKVTEKRCVSVDHKNGMWGVHHCSEKKFFLCLTKNQL 429
L W V + N+ ++M +RC + G+W CS +C K
Sbjct: 884 LRWRDGTPVIYQNWD--KERDRSMNNQSQRCAFISSITGLWDREECSVSMPSICKRKTFW 941
Query: 430 VIEKEFTAPEK 462
VIEKE P++
Sbjct: 942 VIEKEKDTPKQ 952
Score = 28.9 bits (63), Expect = 9.1
Identities = 26/132 (19%), Positives = 57/132 (43%), Gaps = 1/132 (0%)
Frame = +1
Query: 52 NFTDAEEFCSNFSLHRNNSDSHLASIQNQTEVNLIQNWILNLEKKSFWIGGEI-ICSMNA 228
+F A EFC S+L +I+++ E + L ++ F G + + +NA
Sbjct: 1270 SFEAAHEFCKK-------EGSNLLTIKDEAENSF-------LLEEPFAFGASVQMVWLNA 1315
Query: 229 LLDRMFLLHWISNDKVEFTNFKVPNYNVKNMKVTEKRCVSVDHKNGMWGVHHCSEKKFFL 408
D + W+ + +N+ + ++ + + +C+++ G+W + C + F+
Sbjct: 1316 QFDNE-TVKWLDGTPADQSNWGIRKPDMAHFE--PHQCLALRIPEGVWQLSPCQKNMGFI 1372
Query: 409 CLTKNQLVIEKE 444
C K + KE
Sbjct: 1373 CKMKADIHTVKE 1384
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,111,677
Number of Sequences: 369166
Number of extensions: 1003093
Number of successful extensions: 2732
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2649
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2720
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 4029688280
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)