Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_021_E20 (754 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9UHB6|EPLIN_HUMAN Epithelial protein lost in neoplasm 78 3e-14 sp|Q9ERG0|EPLIN_MOUSE Epithelial protein lost in neoplasm (... 78 3e-14 sp|P29675|SF3_HELAN Pollen-specific protein SF3 57 4e-08 sp|P34416|LASP1_CAEEL LIM and SH3 domain protein F42H10.3 55 2e-07 sp|Q14847|LASP1_HUMAN LIM and SH3 domain protein 1 (LASP-1)... 53 8e-07 sp|Q99MZ8|LASP1_RAT LIM and SH3 domain protein 1 (LASP-1) 53 8e-07 sp|Q61792|LASP1_MOUSE LIM and SH3 domain protein 1 (LASP-1)... 53 1e-06 sp|O94851|MICA2_HUMAN Protein MICAL-2 51 4e-06 sp|Q8BML1|MICA2_MOUSE Protein MICAL-2 50 6e-06 sp|Q7RTP6|MICA3_HUMAN Protein MICAL-3 49 1e-05
>sp|Q9UHB6|EPLIN_HUMAN Epithelial protein lost in neoplasm Length = 759 Score = 77.8 bits (190), Expect = 3e-14 Identities = 30/57 (52%), Positives = 41/57 (71%) Frame = +3 Query: 3 YPMEKLSTNDKIFHKTCFRCTKCKNALSTGNFSFNHGKPYCTPHYVELFKKRGRYDE 173 YPME+L N ++FH +CFRC+ C N LS G ++ HG+ YC PH+ +LFK +G YDE Sbjct: 398 YPMERLLANQQVFHISCFRCSYCNNKLSLGTYASLHGRIYCKPHFNQLFKSKGNYDE 454
>sp|Q9ERG0|EPLIN_MOUSE Epithelial protein lost in neoplasm (mEPLIN) Length = 753 Score = 77.8 bits (190), Expect = 3e-14 Identities = 30/57 (52%), Positives = 41/57 (71%) Frame = +3 Query: 3 YPMEKLSTNDKIFHKTCFRCTKCKNALSTGNFSFNHGKPYCTPHYVELFKKRGRYDE 173 YPME+L N ++FH +CFRC+ C N LS G ++ HG+ YC PH+ +LFK +G YDE Sbjct: 396 YPMERLLANQQVFHISCFRCSYCNNKLSLGTYASLHGRIYCKPHFNQLFKSKGNYDE 452
>sp|P29675|SF3_HELAN Pollen-specific protein SF3 Length = 219 Score = 57.4 bits (137), Expect = 4e-08 Identities = 27/103 (26%), Positives = 50/103 (48%) Frame = +3 Query: 3 YPMEKLSTNDKIFHKTCFRCTKCKNALSTGNFSFNHGKPYCTPHYVELFKKRGRYDEIDD 182 YP+E++ + +H+ CF+C +S N+ + G+ YC H+++LFKK+G Y +++ Sbjct: 118 YPIERVKVDGTAYHRACFKCCHGGCTISPSNYIAHEGRLYCKHHHIQLFKKKGNYSQLE- 176 Query: 183 NIENEILATNDISDVLTDELPAPDTTKNILAKFRDLQTGGNSN 311 +E + A PA T+N + + Q N Sbjct: 177 -VEETVAA------------PAESETQNTETQNAETQNADTQN 206
Score = 57.0 bits (136), Expect = 5e-08 Identities = 23/60 (38%), Positives = 35/60 (58%) Frame = +3 Query: 3 YPMEKLSTNDKIFHKTCFRCTKCKNALSTGNFSFNHGKPYCTPHYVELFKKRGRYDEIDD 182 Y ++KL N +++HK CFRC C + L NF+ G YC H+ +LFK+ G ++ D Sbjct: 19 YLVDKLVANQRVYHKACFRCHHCNSTLKLSNFNSFDGVVYCRHHFDQLFKRTGSLEKSFD 78
>sp|P34416|LASP1_CAEEL LIM and SH3 domain protein F42H10.3 Length = 335 Score = 55.1 bits (131), Expect = 2e-07 Identities = 21/45 (46%), Positives = 29/45 (64%) Frame = +3 Query: 3 YPMEKLSTNDKIFHKTCFRCTKCKNALSTGNFSFNHGKPYCTPHY 137 YP+E+L DK++HK CF+CT C L+ N+ +PYC PHY Sbjct: 15 YPVEELKCLDKVWHKQCFKCTVCGMTLNMKNYKGYDKRPYCDPHY 59
>sp|Q14847|LASP1_HUMAN LIM and SH3 domain protein 1 (LASP-1) (MLN 50) Length = 261 Score = 53.1 bits (126), Expect = 8e-07 Identities = 21/45 (46%), Positives = 26/45 (57%) Frame = +3 Query: 3 YPMEKLSTNDKIFHKTCFRCTKCKNALSTGNFSFNHGKPYCTPHY 137 YP EK++ DK +HK CF C CK L+ N+ KPYC HY Sbjct: 13 YPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHY 57
>sp|Q99MZ8|LASP1_RAT LIM and SH3 domain protein 1 (LASP-1) Length = 263 Score = 53.1 bits (126), Expect = 8e-07 Identities = 21/45 (46%), Positives = 26/45 (57%) Frame = +3 Query: 3 YPMEKLSTNDKIFHKTCFRCTKCKNALSTGNFSFNHGKPYCTPHY 137 YP EK++ DK +HK CF C CK L+ N+ KPYC HY Sbjct: 13 YPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHY 57
>sp|Q61792|LASP1_MOUSE LIM and SH3 domain protein 1 (LASP-1) (MLN 50) Length = 263 Score = 52.8 bits (125), Expect = 1e-06 Identities = 21/45 (46%), Positives = 26/45 (57%) Frame = +3 Query: 3 YPMEKLSTNDKIFHKTCFRCTKCKNALSTGNFSFNHGKPYCTPHY 137 YP EK++ DK +HK CF C CK L+ N+ KPYC HY Sbjct: 13 YPTEKVNCLDKYWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHY 57
>sp|O94851|MICA2_HUMAN Protein MICAL-2 Length = 1124 Score = 50.8 bits (120), Expect = 4e-06 Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 5/70 (7%) Frame = +3 Query: 3 YPMEKLSTNDKIFHKTCFRCTKCKNALSTGNFSF--NHGKPYCTPHYVEL---FKKRGRY 167 Y ME+LS FH+ CFRC+ C L ++F + GK YC PH++ K+R R Sbjct: 1010 YVMERLSAEGHFFHRECFRCSICATTLRLAAYTFDCDEGKFYCKPHFIHCKTNSKQRKRR 1069 Query: 168 DEIDDNIENE 197 E+ E E Sbjct: 1070 AELKQQREEE 1079
>sp|Q8BML1|MICA2_MOUSE Protein MICAL-2 Length = 960 Score = 50.1 bits (118), Expect = 6e-06 Identities = 26/70 (37%), Positives = 37/70 (52%), Gaps = 5/70 (7%) Frame = +3 Query: 3 YPMEKLSTNDKIFHKTCFRCTKCKNALSTGNFSF--NHGKPYCTPHYVEL---FKKRGRY 167 Y +E+LS FH+ CFRC+ C L ++F + GK YC PH+V K+R R Sbjct: 761 YMIERLSAEGHFFHQECFRCSVCSATLRLAAYAFDCDEGKFYCKPHFVHCKTSSKQRKRR 820 Query: 168 DEIDDNIENE 197 E++ E E Sbjct: 821 AELNQQREEE 830
>sp|Q7RTP6|MICA3_HUMAN Protein MICAL-3 Length = 976 Score = 48.9 bits (115), Expect = 1e-05 Identities = 20/47 (42%), Positives = 28/47 (59%), Gaps = 2/47 (4%) Frame = +3 Query: 3 YPMEKLSTNDKIFHKTCFRCTKCKNALSTGNFSFN--HGKPYCTPHY 137 Y ME+LS K FH++CF+C C L ++++ GK YC PHY Sbjct: 800 YVMERLSAEGKFFHRSCFKCEYCATTLRLSAYAYDIEDGKFYCKPHY 846
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 89,231,218 Number of Sequences: 369166 Number of extensions: 1901536 Number of successful extensions: 5503 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5165 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5498 length of database: 68,354,980 effective HSP length: 108 effective length of database: 48,403,600 effective search space used: 6873311200 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)