Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_021_D17
(830 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9BXT6|M10L1_HUMAN Putative helicase Mov10l1 (Moloney le... 167 3e-41
sp|Q6J5K9|ARMI_DROME Probable RNA helicase armi (Armitage p... 162 1e-39
sp|Q99MV5|M10L1_MOUSE Putative helicase Mov10l1 (Moloney le... 131 2e-30
sp|Q8GYD9|SDE3_ARATH Probable RNA helicase SDE3 (Silencing ... 123 7e-28
sp|Q9HCE1|MOV10_HUMAN Putative helicase MOV-10 (Moloney leu... 119 8e-27
sp|P23249|MOV10_MOUSE Putative helicase MOV-10 (Moloney leu... 116 9e-26
sp|P34243|YKB7_YEAST Hypothetical 78.3 kDa protein in RAM2-... 59 2e-08
sp|Q9HEH1|RENT1_NEUCR Regulator of nonsense transcripts 1 h... 56 1e-07
sp|Q57568|Y104_METJA Hypothetical ATP-binding protein MJ0104 56 1e-07
sp|Q60560|SMBP2_MESAU DNA-binding protein SMUBP-2 (Immunogl... 56 1e-07
>sp|Q9BXT6|M10L1_HUMAN Putative helicase Mov10l1 (Moloney leukemia virus 10-like protein 1)
(MOV10-like 1)
Length = 1211
Score = 167 bits (424), Expect = 3e-41
Identities = 112/317 (35%), Positives = 165/317 (52%), Gaps = 43/317 (13%)
Frame = +1
Query: 1 INTKEEMKQFLLENVRLIRRRETFGIEVPGLSEGRPSLIVGDKVNVKVN*ET--AIVFSG 174
I + E+K++ + + L R + +EVPGL+EGRPSL GDK+ +K AI +
Sbjct: 543 IYAEMELKEYNMSGIILRRNGDLLVLEVPGLAEGRPSLYAGDKLILKTQEYNGHAIEYIS 602
Query: 175 TIEDILCDLIFVKFHETLHSNYTNEECTVTFGHSRLPFRRIHLGIEVGCGILGDRILFPE 354
+ +I + + +K + Y E V F ++R RR H +E LG ++LFPE
Sbjct: 603 YVTEIHEEDVTLKINPEFEQAYNFEPMDVEFTYNRTTSRRCHFALEHVIH-LGVKVLFPE 661
Query: 355 KIEMKPSQCV--------------------------------RLSRSGCNEISAINFVKV 438
+I ++ Q R G ++ +
Sbjct: 662 EIILQSPQVTGNWNHAQDTKSSGQSTSKKNRKTMTDQAEHGTEERRVGDKDLPVLAPFTA 721
Query: 439 EAYNML---------QLKFYNESLNELQRVAVLRILHGYSRPLPYILFGPPGTGKTVTLV 591
E + + +++F+N LNE Q++AV RIL G RPLPYILFGPPGTGKTVT++
Sbjct: 722 EMSDWVDEIQTPKARKMEFFNPVLNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTII 781
Query: 592 EAILQVYKNIPSSRILLCAPSNSAADLLCLRLDESVIIESGEMVRMNAFRRTILSEMSDK 771
EA+LQV+ +P SRIL+CAPSNSAADL+CLRL ES +++ MVR+NA R +
Sbjct: 782 EAVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKVLQPATMVRVNATCRF-------E 834
Query: 772 EPIPPRVLPYCKSIDDV 822
E + V PYC+ +D+
Sbjct: 835 EIVIDAVKPYCRDGEDI 851
>sp|Q6J5K9|ARMI_DROME Probable RNA helicase armi (Armitage protein)
Length = 1274
Score = 162 bits (409), Expect = 1e-39
Identities = 88/267 (32%), Positives = 151/267 (56%), Gaps = 7/267 (2%)
Frame = +1
Query: 37 ENVRLIRRRETFGIEVPGLSEGRPSLIVGDKVNV-----KVN*ETAIVFSGTIEDILCDL 201
+ +R E +++ L+E RPSL++GD + V + +T + G I +L D
Sbjct: 641 DRAHFLRDGEFLTLQIENLAERRPSLVIGDTLRVINPWSDPDSQTTKSYEGIIHKVLFDR 700
Query: 202 IFVKFHETLHSNYTNEECTVTFGHSRLPFRRIHLGIEVGCGILGDRILFPEKIEMKPSQC 381
I +KFH + Y E+ + F SR FR+ H I G++G+ LFP K+ + +
Sbjct: 701 ILLKFHSSFQEKYNGEDYRLEFYFSRYSFRKQHHAISKIVGVMGEDFLFPSKVTKRENPQ 760
Query: 382 VRLSRSGCNEISAINFVKVEAYNML--QLKFYNESLNELQRVAVLRILHGYSRPLPYILF 555
+ + ++K + + +L++YN+SLN +Q+ AV IL G + +PY+LF
Sbjct: 761 LDV------------YMKDDDMYLYDSKLEWYNQSLNSIQKRAVFNILRGEAENIPYVLF 808
Query: 556 GPPGTGKTVTLVEAILQVYKNIPSSRILLCAPSNSAADLLCLRLDESVIIESGEMVRMNA 735
GPPG+GKT+TL+E +LQ+ +N+P +RIL+ PSNS+ADL+ RL +S + G+ +R+ +
Sbjct: 809 GPPGSGKTMTLIETLLQLVRNLPGARILVGTPSNSSADLVTKRLIDSKALLQGDFIRLVS 868
Query: 736 FRRTILSEMSDKEPIPPRVLPYCKSID 816
+ + +K+ IPP ++ YC + D
Sbjct: 869 YNQV------EKDLIPPEIMSYCATSD 889
>sp|Q99MV5|M10L1_MOUSE Putative helicase Mov10l1 (Moloney leukemia virus 10-like protein 1)
(MOV10-like 1) (Cardiac helicase activated by MEF2
protein) (Cardiac-specific RNA helicase)
Length = 1187
Score = 131 bits (330), Expect = 2e-30
Identities = 68/120 (56%), Positives = 87/120 (72%)
Frame = +1
Query: 463 KFYNESLNELQRVAVLRILHGYSRPLPYILFGPPGTGKTVTLVEAILQVYKNIPSSRILL 642
+F+N LNE Q++AV RIL G RPLPYILFGPPGTGKTVT++EA+LQV+ +P SRIL+
Sbjct: 741 EFFNPVLNENQKLAVRRILSGDCRPLPYILFGPPGTGKTVTIIEAVLQVHYALPDSRILV 800
Query: 643 CAPSNSAADLLCLRLDESVIIESGEMVRMNAFRRTILSEMSDKEPIPPRVLPYCKSIDDV 822
CAPSNSAADL+CLRL ES + + MVR+NA R +E I + PYC+ +D+
Sbjct: 801 CAPSNSAADLVCLRLHESKVPKPAAMVRVNATCRF-------EETIIDAIKPYCRDGEDI 853
Score = 61.2 bits (147), Expect = 3e-09
Identities = 41/128 (32%), Positives = 68/128 (53%), Gaps = 2/128 (1%)
Frame = +1
Query: 1 INTKEEMKQFLLENVRLIRRRETFGIEVPGLSEGRPSLIVGDKVNVKVN*ET--AIVFSG 174
I+ + E+K++ + V L R+ + +EVPGL+E RPSL GDK+ +K I + G
Sbjct: 483 IHAEIELKEYNMSRVVLKRKGDLLVLEVPGLAESRPSLYAGDKLILKSQEYNGHVIEYIG 542
Query: 175 TIEDILCDLIFVKFHETLHSNYTNEECTVTFGHSRLPFRRIHLGIEVGCGILGDRILFPE 354
+ +I + + +K + Y E V F ++R RR H +E LG ++LFPE
Sbjct: 543 YVMEIHEEDVTLKLNPGFEQMYNFEPMDVEFTYNRTTSRRCHYALEQVIH-LGVKVLFPE 601
Query: 355 KIEMKPSQ 378
+I ++ Q
Sbjct: 602 EIILQSPQ 609
>sp|Q8GYD9|SDE3_ARATH Probable RNA helicase SDE3 (Silencing defective protein 3)
Length = 1002
Score = 123 bits (308), Expect = 7e-28
Identities = 91/276 (32%), Positives = 140/276 (50%), Gaps = 8/276 (2%)
Frame = +1
Query: 1 INTKEEMKQFLLENVRLIRRRETFGIEVPGLSEGRPSLIVGDKVNVK--VN*ETAIVFSG 174
+ +E+M+ + +ENV + RR +EVPGL+E RPSL+ GD + V+ + T + G
Sbjct: 258 LQLEEDMRAYDMENVSMKRRGIYLSLEVPGLAERRPSLVHGDFIFVRHAYDDGTDHAYQG 317
Query: 175 TIEDILCDLIFVKFHETLHSNYT-NEECTVTFGHSRLPFRRIHLGIEVGCGILGDRILFP 351
+ + D + +KF H +T V F ++R+ RR++ ++ +L LFP
Sbjct: 318 FVHRVEADEVHMKFASEFHQRHTAGSVYNVRFTYNRINTRRLYQAVDAA-EMLDPNFLFP 376
Query: 352 EKIEMKPSQCVRLSRSGCNEISAINFVKVEAYNMLQLKFYNESLNELQRVAVLRILHGYS 531
SG I FV + + +LN Q ++ +L
Sbjct: 377 SL------------HSGKRMIKTKPFVPI-----------SPALNAEQICSIEMVLGCKG 413
Query: 532 RPLPYILFGPPGTGKTVTLVEAILQVYKNIPSSRILLCAPSNSAAD-----LLCLRLDES 696
P PY++ GPPGTGKT+TLVEAI+Q+Y ++R+L+CAPSNSAAD LLCL E
Sbjct: 414 AP-PYVIHGPPGTGKTMTLVEAIVQLYTTQRNARVLVCAPSNSAADHILEKLLCL---EG 469
Query: 697 VIIESGEMVRMNAFRRTILSEMSDKEPIPPRVLPYC 804
V I+ E+ R+NA R+ E I P ++ +C
Sbjct: 470 VRIKDNEIFRLNAATRSY-------EEIKPEIIRFC 498
>sp|Q9HCE1|MOV10_HUMAN Putative helicase MOV-10 (Moloney leukemia virus 10 protein)
Length = 1003
Score = 119 bits (299), Expect = 8e-27
Identities = 86/250 (34%), Positives = 124/250 (49%), Gaps = 7/250 (2%)
Frame = +1
Query: 76 IEVPGLSEGRPSLIVGDKVNVKVN*ET----AIVFSGTIEDILCDLIFVKFHETLHSNYT 243
+EVPG++E RPS++ GD + ++ ET I + G + + D + + F +L S +
Sbjct: 379 LEVPGVTESRPSVLRGDHLFALLSSETHQEDPITYKGFVHKVELDRVKLSFSMSLLSRFV 438
Query: 244 NE-ECTVTFGHSRLPFRRIHLGIEVGCGILGDRILFPEKIEMKPSQCVRLSRSGCNEISA 420
+ V F +R P R H +E + G +L+P + P L
Sbjct: 439 DGLTFKVNFTFNRQPLRVQHRALE----LTGRWLLWPMLFPVAPRDVPLLPSD------- 487
Query: 421 INFVKVEAYNMLQLKFYNESL--NELQRVAVLRILHGYSRPLPYILFGPPGTGKTVTLVE 594
++LK Y+ SL N Q A+ I+ G +RP PYI+FGPPGTGKTVTLVE
Sbjct: 488 -----------VKLKLYDRSLESNPEQLQAMRHIVTGTTRPAPYIIFGPPGTGKTVTLVE 536
Query: 595 AILQVYKNIPSSRILLCAPSNSAADLLCLRLDESVIIESGEMVRMNAFRRTILSEMSDKE 774
AI QV K++P + IL CAPSNS ADLLC RL V + + +L+ D
Sbjct: 537 AIKQVVKHLPKAHILACAPSNSGADLLCQRL----------RVHLPSSIYRLLAPSRDIR 586
Query: 775 PIPPRVLPYC 804
+P + P C
Sbjct: 587 MVPEDIKPCC 596
>sp|P23249|MOV10_MOUSE Putative helicase MOV-10 (Moloney leukemia virus 10 protein)
Length = 1004
Score = 116 bits (290), Expect = 9e-26
Identities = 80/211 (37%), Positives = 114/211 (54%), Gaps = 7/211 (3%)
Frame = +1
Query: 76 IEVPGLSEGRPSLIVGDKVNVKVN*ETA----IVFSGTIEDILCDLIFVKFHETLHSNYT 243
+EVPG++E RPS++ GD + ++ ET + + G + + D + + F +L S +
Sbjct: 380 LEVPGVAESRPSVLRGDHLFALLSSETQQDDPVTYKGFVHKVELDRVKLSFSTSLLSRFV 439
Query: 244 NE-ECTVTFGHSRLPFRRIHLGIEVGCGILGDRILFPEKIEMKPSQCVRLSRSGCNEISA 420
+ V F +R P R H +E + G +L+P + S+ V L S
Sbjct: 440 DGLTFKVNFTFNRQPLRVQHRALE----LTGRWVLWPMLFPVA-SRGVSLLPSD------ 488
Query: 421 INFVKVEAYNMLQLKFYNESL--NELQRVAVLRILHGYSRPLPYILFGPPGTGKTVTLVE 594
++ K Y+ SL N Q A+ I+ G +RP PYI+FGPPGTGKTVTLVE
Sbjct: 489 -----------VKFKLYDRSLESNPEQLQAMKHIVRGTTRPAPYIIFGPPGTGKTVTLVE 537
Query: 595 AILQVYKNIPSSRILLCAPSNSAADLLCLRL 687
AI QV K++P + IL CAPSNS ADLLC RL
Sbjct: 538 AIKQVVKHLPKAHILACAPSNSGADLLCQRL 568
>sp|P34243|YKB7_YEAST Hypothetical 78.3 kDa protein in RAM2-ATP7 intergenic region
Length = 683
Score = 58.5 bits (140), Expect = 2e-08
Identities = 38/110 (34%), Positives = 59/110 (53%), Gaps = 5/110 (4%)
Frame = +1
Query: 466 FYNESLNELQRVAVLRILHGYSRPLPYILFGPPGTGKTVTLVEAILQVYKNIPSSRILLC 645
F N +LN+ Q+ A+ ++ I+ GPPGTGKT TL+E I Q+ P RIL+C
Sbjct: 203 FLNPNLNDSQKTAINFAINNDLT----IIHGPPGTGKTFTLIELIQQLLIKNPEERILIC 258
Query: 646 APSNSAADLLCLRL----DESVIIESGEMVR-MNAFRRTILSEMSDKEPI 780
PSN + D + RL ++++ G R +++ +R L +S K I
Sbjct: 259 GPSNISVDTILERLTPLVPNNLLLRIGHPARLLDSNKRHSLDILSKKNTI 308
>sp|Q9HEH1|RENT1_NEUCR Regulator of nonsense transcripts 1 homolog
Length = 1093
Score = 56.2 bits (134), Expect = 1e-07
Identities = 38/94 (40%), Positives = 52/94 (55%)
Frame = +1
Query: 463 KFYNESLNELQRVAVLRILHGYSRPLPYILFGPPGTGKTVTLVEAILQVYKNIPSSRILL 642
KF+ L EL + I S PL I GPPGTGKTVT I + K + +S++L+
Sbjct: 447 KFHVPGLPELNASQIAAIKQVLSNPLSLIQ-GPPGTGKTVTSATIIYHLAK-MSNSQVLV 504
Query: 643 CAPSNSAADLLCLRLDESVIIESGEMVRMNAFRR 744
CAPSN A D LC R+ + + ++VR+ A R
Sbjct: 505 CAPSNVAVDQLCERIHRTGL----KVVRLTAKSR 534
>sp|Q57568|Y104_METJA Hypothetical ATP-binding protein MJ0104
Length = 663
Score = 56.2 bits (134), Expect = 1e-07
Identities = 33/72 (45%), Positives = 49/72 (68%)
Frame = +1
Query: 454 LQLKFYNESLNELQRVAVLRILHGYSRPLPYILFGPPGTGKTVTLVEAILQVYKNIPSSR 633
++L+FY+++LNE Q++AV + + SR L Y++ GPPGTGKT T+ E I+Q K +
Sbjct: 176 IKLEFYDKNLNESQKLAVKKAV--LSRDL-YLIHGPPGTGKTRTITEVIVQEVK-FNKHK 231
Query: 634 ILLCAPSNSAAD 669
+L A SN AAD
Sbjct: 232 VLATADSNIAAD 243
>sp|Q60560|SMBP2_MESAU DNA-binding protein SMUBP-2 (Immunoglobulin mu-binding protein 2)
(SMUBP-2) (Insulin II gene enhancer-binding protein)
(RIPE3B-binding complex 3B2 p110 subunit) (RIP-1)
Length = 989
Score = 55.8 bits (133), Expect = 1e-07
Identities = 36/74 (48%), Positives = 44/74 (59%)
Frame = +1
Query: 466 FYNESLNELQRVAVLRILHGYSRPLPYILFGPPGTGKTVTLVEAILQVYKNIPSSRILLC 645
FYN +L+ Q+ AV L ++ I+ GPPGTGKT T+VE ILQ K +IL C
Sbjct: 186 FYNTALDPSQKEAVSFAL---AQKEVAIIHGPPGTGKTTTVVEIILQAVKQ--GLKILCC 240
Query: 646 APSNSAADLLCLRL 687
APSN A D L RL
Sbjct: 241 APSNVAVDNLVERL 254
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,334,835
Number of Sequences: 369166
Number of extensions: 1853948
Number of successful extensions: 7187
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6783
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7156
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8052550455
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)