Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_021_D10-2
(179 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P43236|CATK_RABIT Cathepsin K precursor (OC-2 protein) 45 5e-05
sp|P43235|CATK_HUMAN Cathepsin K precursor (Cathepsin O) (C... 45 7e-05
sp|P61277|CATK_MACMU Cathepsin K precursor >gi|47117667|sp|... 44 1e-04
sp|Q9GLE3|CATK_PIG Cathepsin K precursor 44 1e-04
sp|O35186|CATK_RAT Cathepsin K precursor 43 2e-04
sp|P25774|CATS_HUMAN Cathepsin S precursor 42 6e-04
sp|P12400|CTL2B_MOUSE CTLA-2-beta protein precursor 41 7e-04
sp|Q8HY82|CATS_SAIBB Cathepsin S precursor 41 0.001
sp|Q9QZE3|CATQ_RAT Cathepsin Q precursor 40 0.001
sp|P55097|CATK_MOUSE Cathepsin K precursor 40 0.002
>sp|P43236|CATK_RABIT Cathepsin K precursor (OC-2 protein)
Length = 329
Score = 45.1 bits (105), Expect = 5e-05
Identities = 23/57 (40%), Positives = 37/57 (64%), Gaps = 1/57 (1%)
Frame = +1
Query: 7 ILSLVVVAITAVPQKFSVNSELNEEWETYKTTFGRKYDELTD-ITRRLIWEQNLKYI 174
+L L VV+ P++ L+ +WE +K T+ ++Y+ D I+RRLIWE+NLK+I
Sbjct: 6 VLLLPVVSFALHPEEI-----LDTQWELWKKTYSKQYNSKVDEISRRLIWEKNLKHI 57
>sp|P43235|CATK_HUMAN Cathepsin K precursor (Cathepsin O) (Cathepsin X) (Cathepsin O2)
Length = 329
Score = 44.7 bits (104), Expect = 7e-05
Identities = 24/57 (42%), Positives = 35/57 (61%), Gaps = 1/57 (1%)
Frame = +1
Query: 7 ILSLVVVAITAVPQKFSVNSELNEEWETYKTTFGRKYDELTD-ITRRLIWEQNLKYI 174
+L L VV+ P++ L+ WE +K T ++Y+ D I+RRLIWE+NLKYI
Sbjct: 6 VLLLPVVSFALYPEEI-----LDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYI 57
>sp|P61277|CATK_MACMU Cathepsin K precursor
sp|P61276|CATK_MACFA Cathepsin K precursor
Length = 329
Score = 43.5 bits (101), Expect = 1e-04
Identities = 23/57 (40%), Positives = 35/57 (61%), Gaps = 1/57 (1%)
Frame = +1
Query: 7 ILSLVVVAITAVPQKFSVNSELNEEWETYKTTFGRKYDELTD-ITRRLIWEQNLKYI 174
+L L V++ P++ L+ WE +K T ++Y+ D I+RRLIWE+NLKYI
Sbjct: 6 VLLLPVMSFALYPEEI-----LDTHWELWKKTHRKQYNSKVDEISRRLIWEKNLKYI 57
>sp|Q9GLE3|CATK_PIG Cathepsin K precursor
Length = 330
Score = 43.5 bits (101), Expect = 1e-04
Identities = 22/58 (37%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Frame = +1
Query: 4 LILSLVVVAITAVPQKFSVNSELNEEWETYKTTFGRKYDELTD-ITRRLIWEQNLKYI 174
++L L V++ P++ L+ +WE +K T+ ++Y+ D I+RRLIWE+NLK+I
Sbjct: 6 VVLLLPVMSSALYPEEI-----LDTQWELWKKTYRKQYNSKVDEISRRLIWEKNLKHI 58
>sp|O35186|CATK_RAT Cathepsin K precursor
Length = 329
Score = 43.1 bits (100), Expect = 2e-04
Identities = 24/56 (42%), Positives = 35/56 (62%), Gaps = 1/56 (1%)
Frame = +1
Query: 10 LSLVVVAITAVPQKFSVNSELNEEWETYKTTFGRKYDELTD-ITRRLIWEQNLKYI 174
L L VV+ P++ L+ +WE +K T G++Y+ D I+RRLIWE+NLK I
Sbjct: 7 LLLPVVSFALSPEE-----TLDTQWELWKKTHGKQYNSKVDEISRRLIWEKNLKKI 57
>sp|P25774|CATS_HUMAN Cathepsin S precursor
Length = 331
Score = 41.6 bits (96), Expect = 6e-04
Identities = 20/57 (35%), Positives = 36/57 (63%), Gaps = 1/57 (1%)
Frame = +1
Query: 7 ILSLVVVAITAVPQKFSVNSELNEEWETYKTTFGRKYDELTD-ITRRLIWEQNLKYI 174
++ +++V +AV Q + L+ W +K T+G++Y E + RRLIWE+NLK++
Sbjct: 4 LVCVLLVCSSAVAQLHK-DPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFV 59
>sp|P12400|CTL2B_MOUSE CTLA-2-beta protein precursor
Length = 141
Score = 41.2 bits (95), Expect = 7e-04
Identities = 21/59 (35%), Positives = 35/59 (59%)
Frame = +1
Query: 1 ILILSLVVVAITAVPQKFSVNSELNEEWETYKTTFGRKYDELTDITRRLIWEQNLKYIQ 177
+ +L L + ++A P S + L+ EW+ +KTTF + Y + RRL+WE+N K I+
Sbjct: 20 VFLLILCLGMMSAAP---SPDPSLDNEWKEWKTTFAKAYSLDEERHRRLMWEENKKKIE 75
>sp|Q8HY82|CATS_SAIBB Cathepsin S precursor
Length = 330
Score = 40.8 bits (94), Expect = 0.001
Identities = 20/57 (35%), Positives = 35/57 (61%), Gaps = 1/57 (1%)
Frame = +1
Query: 7 ILSLVVVAITAVPQKFSVNSELNEEWETYKTTFGRKYDELTD-ITRRLIWEQNLKYI 174
++ ++ V +AV Q + L+ W +K T+G++Y E + RRLIWE+NLK++
Sbjct: 4 LVCVLFVCSSAVTQLHK-DPTLDHHWNLWKKTYGKQYKEKNEEAVRRLIWEKNLKFV 59
>sp|Q9QZE3|CATQ_RAT Cathepsin Q precursor
Length = 343
Score = 40.4 bits (93), Expect = 0.001
Identities = 14/54 (25%), Positives = 34/54 (62%)
Frame = +1
Query: 16 LVVVAITAVPQKFSVNSELNEEWETYKTTFGRKYDELTDITRRLIWEQNLKYIQ 177
LV++ + VP +++ L+ +W+ +K + + Y ++ +R++WE+N+K I+
Sbjct: 7 LVILCLGVVPGASALDLSLDVQWQEWKIKYEKLYSPEEEVLKRVVWEENVKKIE 60
>sp|P55097|CATK_MOUSE Cathepsin K precursor
Length = 329
Score = 39.7 bits (91), Expect = 0.002
Identities = 22/56 (39%), Positives = 34/56 (60%), Gaps = 1/56 (1%)
Frame = +1
Query: 10 LSLVVVAITAVPQKFSVNSELNEEWETYKTTFGRKYDELTD-ITRRLIWEQNLKYI 174
L L +V+ P++ L+ +WE +K T ++Y+ D I+RRLIWE+NLK I
Sbjct: 7 LLLPMVSFALSPEEM-----LDTQWELWKKTHQKQYNSKVDEISRRLIWEKNLKQI 57
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,322,751
Number of Sequences: 369166
Number of extensions: 197648
Number of successful extensions: 705
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 690
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 703
length of database: 68,354,980
effective HSP length: 32
effective length of database: 62,443,460
effective search space used: 1685973420
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)