Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_021_D08
(743 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P51893|SAHHA_XENLA Adenosylhomocysteinase A (S-adenosyl-... 312 5e-85
sp|O93477|SAHHB_XENLA Adenosylhomocysteinase B (S-adenosyl-... 312 7e-85
sp|P50247|SAHH_MOUSE Adenosylhomocysteinase (S-adenosyl-L-h... 310 3e-84
sp|P10760|SAHH_RAT Adenosylhomocysteinase (S-adenosyl-L-hom... 308 1e-83
sp|P27604|SAHH_CAEEL Adenosylhomocysteinase (S-adenosyl-L-h... 307 2e-83
sp|P23526|SAHH_HUMAN Adenosylhomocysteinase (S-adenosyl-L-h... 303 3e-82
sp|Q27580|SAHH_DROME Adenosylhomocysteinase (S-adenosyl-L-h... 302 5e-82
sp|Q710C4|SAHH_PIG Adenosylhomocysteinase (S-adenosyl-L-hom... 302 7e-82
sp|O76757|SAHH_ANOGA Adenosylhomocysteinase (S-adenosyl-L-h... 295 7e-80
sp|O13639|SAHH_SCHPO Adenosylhomocysteinase (S-adenosyl-L-h... 290 2e-78
>sp|P51893|SAHHA_XENLA Adenosylhomocysteinase A (S-adenosyl-L-homocysteine hydrolase A)
(AdoHcyase A)
Length = 433
Score = 312 bits (800), Expect = 5e-85
Identities = 149/194 (76%), Positives = 168/194 (86%)
Frame = +3
Query: 3 VLVSEIDPINALQAAMEGYEVTSVEEAVKKARIFVTATGCKDIIVGRHFEQMLDDSIVCN 182
V+++EIDPINALQAAMEGYEVT+++EA K+ IFVT TGC DI+ GRHFE M DDSIVCN
Sbjct: 240 VIITEIDPINALQAAMEGYEVTTMDEASKEGNIFVTTTGCADIVEGRHFENMKDDSIVCN 299
Query: 183 IGHFDIEVEAKWLYENCKSKDTIKPQVDRYTLKNGRHIILLAEGRLVNLGCAHGHPSFVM 362
IGHFDIE++ KWL EN K IKPQVDRY LKNGRHIILLAEGRLVNLGCA GHPSFVM
Sbjct: 300 IGHFDIELDVKWLNENAVKKVNIKPQVDRYLLKNGRHIILLAEGRLVNLGCAMGHPSFVM 359
Query: 363 SNSFTNQVLAQIELWTKTDQYKVGVYFLPKKLDEEVAQAHLEHLGVKLTKLTPEQSEYLS 542
SNSFTNQV+AQIELWT TD+Y VGVYFLPKKLDE VA AHL+ LGVKLTKLT +Q++YL
Sbjct: 360 SNSFTNQVMAQIELWTNTDKYPVGVYFLPKKLDEAVAAAHLDKLGVKLTKLTDKQAKYLG 419
Query: 543 VPIQGPYKPDHYRY 584
+ +GP+KPDHYRY
Sbjct: 420 LDKEGPFKPDHYRY 433
>sp|O93477|SAHHB_XENLA Adenosylhomocysteinase B (S-adenosyl-L-homocysteine hydrolase B)
(AdoHcyase B)
Length = 433
Score = 312 bits (799), Expect = 7e-85
Identities = 148/194 (76%), Positives = 168/194 (86%)
Frame = +3
Query: 3 VLVSEIDPINALQAAMEGYEVTSVEEAVKKARIFVTATGCKDIIVGRHFEQMLDDSIVCN 182
VL++EIDPINALQAAMEGYEVT+++EA K+ IFVT TGC DI+ GRHFE M DDSIVCN
Sbjct: 240 VLITEIDPINALQAAMEGYEVTTMDEASKEGNIFVTTTGCADIVEGRHFENMKDDSIVCN 299
Query: 183 IGHFDIEVEAKWLYENCKSKDTIKPQVDRYTLKNGRHIILLAEGRLVNLGCAHGHPSFVM 362
IGHFD+E++ KWL +N K IKPQVDRY LKNGRHIILLAEGRLVNLGCA GHPSFVM
Sbjct: 300 IGHFDVELDVKWLNDNAAKKINIKPQVDRYLLKNGRHIILLAEGRLVNLGCAMGHPSFVM 359
Query: 363 SNSFTNQVLAQIELWTKTDQYKVGVYFLPKKLDEEVAQAHLEHLGVKLTKLTPEQSEYLS 542
SNSFTNQV+AQIELWT TD+Y VGVYFLPKKLDE VA AHL+ LGVKLTKLT +Q++YL
Sbjct: 360 SNSFTNQVMAQIELWTNTDKYPVGVYFLPKKLDEAVAAAHLDKLGVKLTKLTDKQAKYLG 419
Query: 543 VPIQGPYKPDHYRY 584
+ +GP+KPDHYRY
Sbjct: 420 LDKEGPFKPDHYRY 433
>sp|P50247|SAHH_MOUSE Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase)
(AdoHcyase) (Liver copper binding protein) (CUBP)
Length = 432
Score = 310 bits (793), Expect = 3e-84
Identities = 147/194 (75%), Positives = 168/194 (86%)
Frame = +3
Query: 3 VLVSEIDPINALQAAMEGYEVTSVEEAVKKARIFVTATGCKDIIVGRHFEQMLDDSIVCN 182
V+++EIDPINALQAAMEGYEVT+++EA K+ IFVT TGC DII+GRHFEQM DD+IVCN
Sbjct: 239 VIITEIDPINALQAAMEGYEVTTMDEACKEGNIFVTTTGCVDIILGRHFEQMKDDAIVCN 298
Query: 183 IGHFDIEVEAKWLYENCKSKDTIKPQVDRYTLKNGRHIILLAEGRLVNLGCAHGHPSFVM 362
IGHFD+E++ KWL EN K IKPQVDRY LKNGR IILLAEGRLVNLGCA GHPSFVM
Sbjct: 299 IGHFDVEIDVKWLNENAVEKVNIKPQVDRYWLKNGRRIILLAEGRLVNLGCAMGHPSFVM 358
Query: 363 SNSFTNQVLAQIELWTKTDQYKVGVYFLPKKLDEEVAQAHLEHLGVKLTKLTPEQSEYLS 542
SNSFTNQV+AQIELWT D+Y VGV+FLPKKLDE VA+AHL L VKLTKLT +Q++YL
Sbjct: 359 SNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLG 418
Query: 543 VPIQGPYKPDHYRY 584
+PI GP+KPDHYRY
Sbjct: 419 MPINGPFKPDHYRY 432
>sp|P10760|SAHH_RAT Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase)
(AdoHcyase)
Length = 432
Score = 308 bits (789), Expect = 1e-83
Identities = 146/194 (75%), Positives = 167/194 (86%)
Frame = +3
Query: 3 VLVSEIDPINALQAAMEGYEVTSVEEAVKKARIFVTATGCKDIIVGRHFEQMLDDSIVCN 182
V+++EIDPINALQAAMEGYEVT+++EA K+ IFVT TGC DII+GRHFEQM DD+IVCN
Sbjct: 239 VIITEIDPINALQAAMEGYEVTTMDEACKEGNIFVTTTGCVDIILGRHFEQMKDDAIVCN 298
Query: 183 IGHFDIEVEAKWLYENCKSKDTIKPQVDRYTLKNGRHIILLAEGRLVNLGCAHGHPSFVM 362
IGHFD+E++ KWL EN K IKPQVDRY LKNG IILLAEGRLVNLGCA GHPSFVM
Sbjct: 299 IGHFDVEIDVKWLNENAVEKVNIKPQVDRYLLKNGHRIILLAEGRLVNLGCAMGHPSFVM 358
Query: 363 SNSFTNQVLAQIELWTKTDQYKVGVYFLPKKLDEEVAQAHLEHLGVKLTKLTPEQSEYLS 542
SNSFTNQV+AQIELWT D+Y VGV+FLPKKLDE VA+AHL L VKLTKLT +Q++YL
Sbjct: 359 SNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLG 418
Query: 543 VPIQGPYKPDHYRY 584
+PI GP+KPDHYRY
Sbjct: 419 MPINGPFKPDHYRY 432
>sp|P27604|SAHH_CAEEL Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase)
(AdoHcyase) (Dumpy-14 protein)
Length = 437
Score = 307 bits (787), Expect = 2e-83
Identities = 146/197 (74%), Positives = 166/197 (84%), Gaps = 3/197 (1%)
Frame = +3
Query: 3 VLVSEIDPINALQAAMEGYEVTSVEEAVKKARIFVTATGCKDIIVGRHFEQMLDDSIVCN 182
V+V+EIDPINALQAAMEGYEVT++EEA KA I VT TGCKDI+ G+HFE + +D+IVCN
Sbjct: 241 VIVTEIDPINALQAAMEGYEVTTLEEAAPKANIIVTTTGCKDIVTGKHFELLPNDAIVCN 300
Query: 183 IGHFDIEVEAKWLYENCKSKDTIKPQVDRYTLKNGRHIILLAEGRLVNLGCAHGHPSFVM 362
+GHFD E++ KWL N KDTIKPQVDRYTLKNGRH+ILLAEGRLVNLGCA GHPSFVM
Sbjct: 301 VGHFDCEIDVKWLNTNATKKDTIKPQVDRYTLKNGRHVILLAEGRLVNLGCATGHPSFVM 360
Query: 363 SNSFTNQVLAQIELWTK---TDQYKVGVYFLPKKLDEEVAQAHLEHLGVKLTKLTPEQSE 533
SNSFTNQVLAQ+ELWTK +YK+G+Y LPK LDEEVA HL LGVKLTKL+ EQ+
Sbjct: 361 SNSFTNQVLAQVELWTKFGTPQEYKLGLYVLPKTLDEEVAYLHLAQLGVKLTKLSDEQAS 420
Query: 534 YLSVPIQGPYKPDHYRY 584
YL VP+ GPYKPDHYRY
Sbjct: 421 YLGVPVAGPYKPDHYRY 437
>sp|P23526|SAHH_HUMAN Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase)
(AdoHcyase)
Length = 432
Score = 303 bits (776), Expect = 3e-82
Identities = 144/194 (74%), Positives = 166/194 (85%)
Frame = +3
Query: 3 VLVSEIDPINALQAAMEGYEVTSVEEAVKKARIFVTATGCKDIIVGRHFEQMLDDSIVCN 182
V+++EIDPINALQAAMEGYEVT+++EA ++ IFVT TGC DII+GRHFEQM DD+IVCN
Sbjct: 239 VIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCN 298
Query: 183 IGHFDIEVEAKWLYENCKSKDTIKPQVDRYTLKNGRHIILLAEGRLVNLGCAHGHPSFVM 362
IGHFD+E++ KWL EN K IKPQVDRY LKNGR IILLAEGRLVNLGCA GHPSFVM
Sbjct: 299 IGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVM 358
Query: 363 SNSFTNQVLAQIELWTKTDQYKVGVYFLPKKLDEEVAQAHLEHLGVKLTKLTPEQSEYLS 542
SNSFTNQV+AQIELWT D+Y VGV+FLPKKLDE VA+AHL L VKLTKLT +Q++YL
Sbjct: 359 SNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLG 418
Query: 543 VPIQGPYKPDHYRY 584
+ GP+KPDHYRY
Sbjct: 419 MSCDGPFKPDHYRY 432
>sp|Q27580|SAHH_DROME Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase)
(AdoHcyase)
Length = 432
Score = 302 bits (774), Expect = 5e-82
Identities = 144/194 (74%), Positives = 166/194 (85%)
Frame = +3
Query: 3 VLVSEIDPINALQAAMEGYEVTSVEEAVKKARIFVTATGCKDIIVGRHFEQMLDDSIVCN 182
V+V+E+DPINALQAAMEGYEVT++EEA K+A IFVT TGC+DII H +QM DD+IVCN
Sbjct: 239 VIVTEVDPINALQAAMEGYEVTTMEEASKEASIFVTTTGCRDIITSVHLQQMPDDAIVCN 298
Query: 183 IGHFDIEVEAKWLYENCKSKDTIKPQVDRYTLKNGRHIILLAEGRLVNLGCAHGHPSFVM 362
IGHFDIE++ WL N K K +KPQVDRYT+++G+HIILLAEGRLVNLGCAHGHPSFVM
Sbjct: 299 IGHFDIEIDVDWLNANAKEKVNVKPQVDRYTMQSGKHIILLAEGRLVNLGCAHGHPSFVM 358
Query: 363 SNSFTNQVLAQIELWTKTDQYKVGVYFLPKKLDEEVAQAHLEHLGVKLTKLTPEQSEYLS 542
SNSFTNQVLAQIELWTK+D+Y VGV+ LPK LDEEVA HLE LGVKLTKLT +Q+ YL
Sbjct: 359 SNSFTNQVLAQIELWTKSDKYAVGVHVLPKILDEEVASLHLEKLGVKLTKLTEKQATYLG 418
Query: 543 VPIQGPYKPDHYRY 584
V GP+KPDHYRY
Sbjct: 419 VSQTGPFKPDHYRY 432
>sp|Q710C4|SAHH_PIG Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase)
(AdoHcyase)
Length = 432
Score = 302 bits (773), Expect = 7e-82
Identities = 144/194 (74%), Positives = 166/194 (85%)
Frame = +3
Query: 3 VLVSEIDPINALQAAMEGYEVTSVEEAVKKARIFVTATGCKDIIVGRHFEQMLDDSIVCN 182
V+++EIDPINALQAAMEGYEVT+++EA ++ IFVT TGC DII+GRHFEQM DD+IVCN
Sbjct: 239 VIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCN 298
Query: 183 IGHFDIEVEAKWLYENCKSKDTIKPQVDRYTLKNGRHIILLAEGRLVNLGCAHGHPSFVM 362
IGHFD+E++ KWL EN K IKPQVDRY LKNG IILLAEGRLVNLGCA GHPSFVM
Sbjct: 299 IGHFDVEIDVKWLNENAVEKVNIKPQVDRYLLKNGHRIILLAEGRLVNLGCAMGHPSFVM 358
Query: 363 SNSFTNQVLAQIELWTKTDQYKVGVYFLPKKLDEEVAQAHLEHLGVKLTKLTPEQSEYLS 542
SNSFTNQVLAQIELWT D+Y VGV+FLPKKLDE VA+AHL L VKLTKLT +Q++YL
Sbjct: 359 SNSFTNQVLAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLG 418
Query: 543 VPIQGPYKPDHYRY 584
+ +GP+KPDHYRY
Sbjct: 419 MSREGPFKPDHYRY 432
>sp|O76757|SAHH_ANOGA Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase)
(AdoHcyase)
Length = 432
Score = 295 bits (756), Expect = 7e-80
Identities = 142/194 (73%), Positives = 161/194 (82%)
Frame = +3
Query: 3 VLVSEIDPINALQAAMEGYEVTSVEEAVKKARIFVTATGCKDIIVGRHFEQMLDDSIVCN 182
VL++EIDPINALQAAMEG EVT++EEA K+A+IFVT TGC DII+G HF M DDSIVCN
Sbjct: 239 VLITEIDPINALQAAMEGKEVTTMEEASKEAQIFVTTTGCTDIIMGEHFLNMKDDSIVCN 298
Query: 183 IGHFDIEVEAKWLYENCKSKDTIKPQVDRYTLKNGRHIILLAEGRLVNLGCAHGHPSFVM 362
IGHFD E+ WL EN K IKPQVDRY L NG HIILLAEGRLVNLGCA GH SFVM
Sbjct: 299 IGHFDCEINVTWLQENAVEKVNIKPQVDRYRLANGNHIILLAEGRLVNLGCAMGHSSFVM 358
Query: 363 SNSFTNQVLAQIELWTKTDQYKVGVYFLPKKLDEEVAQAHLEHLGVKLTKLTPEQSEYLS 542
SNSFTNQVLAQIELWT +QY +GV+ LPKKLD+EVA HL+ LGVKLTKL+ Q EYL+
Sbjct: 359 SNSFTNQVLAQIELWTNREQYAIGVHVLPKKLDDEVAALHLDKLGVKLTKLSARQPEYLN 418
Query: 543 VPIQGPYKPDHYRY 584
+P++GPYKP+HYRY
Sbjct: 419 LPVEGPYKPEHYRY 432
>sp|O13639|SAHH_SCHPO Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase)
(AdoHcyase)
Length = 433
Score = 290 bits (743), Expect = 2e-78
Identities = 138/194 (71%), Positives = 160/194 (82%)
Frame = +3
Query: 3 VLVSEIDPINALQAAMEGYEVTSVEEAVKKARIFVTATGCKDIIVGRHFEQMLDDSIVCN 182
V+V+E+DPINALQAAM+G+EVT++EEAVK+ +IFVT TGC+DII G HF +M +DSIVCN
Sbjct: 240 VIVTEVDPINALQAAMDGFEVTTMEEAVKEGQIFVTTTGCRDIIRGEHFNEMKEDSIVCN 299
Query: 183 IGHFDIEVEAKWLYENCKSKDTIKPQVDRYTLKNGRHIILLAEGRLVNLGCAHGHPSFVM 362
IGHFD+E++ WL N K IKPQVDRY LKNGRHIILLA+GRLVNLGCA GHPSFVM
Sbjct: 300 IGHFDVEIDVAWLKANAKDVVNIKPQVDRYELKNGRHIILLADGRLVNLGCATGHPSFVM 359
Query: 363 SNSFTNQVLAQIELWTKTDQYKVGVYFLPKKLDEEVAQAHLEHLGVKLTKLTPEQSEYLS 542
S SFTNQVLAQI LWT Y +GV+ LPKKLDEEVA+ HL LGVKLT LT QS+YL
Sbjct: 360 SCSFTNQVLAQIALWTDNTSYPLGVHMLPKKLDEEVARLHLGKLGVKLTTLTSVQSDYLG 419
Query: 543 VPIQGPYKPDHYRY 584
+P+ GPYK DHYRY
Sbjct: 420 IPVDGPYKADHYRY 433
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,976,625
Number of Sequences: 369166
Number of extensions: 1813315
Number of successful extensions: 4787
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4537
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4681
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6728100400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)