Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_021_D07
(825 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P63045|VAMP2_RAT Vesicle-associated membrane protein 2 (... 129 1e-29
sp|P63026|VAMP2_BOVIN Vesicle-associated membrane protein 2... 127 4e-29
sp|P23763|VAM1_HUMAN Vesicle-associated membrane protein 1 ... 122 2e-27
sp|P47194|SYB_LOLPE Synaptobrevin 122 2e-27
sp|Q62442|VAMP1_MOUSE Vesicle-associated membrane protein 1... 121 2e-27
sp|Q63666|VAMP1_RAT Vesicle-associated membrane protein 1 (... 118 2e-26
sp|P47193|VAMP2_XENLA Vesicle-associated membrane protein 2... 117 3e-26
sp|P13701|SYB_TORCA Synaptobrevin (Synaptic vesicle-associa... 117 3e-26
sp|P35589|SYB_APLCA Synaptobrevin 115 1e-25
sp|Q15836|VAM3_HUMAN Vesicle-associated membrane protein 3 ... 113 7e-25
>sp|P63045|VAMP2_RAT Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
sp|P63044|VAMP2_MOUSE Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Length = 116
Score = 129 bits (323), Expect = 1e-29
Identities = 67/94 (71%), Positives = 76/94 (80%), Gaps = 1/94 (1%)
Frame = +1
Query: 19 MAANSQTVPGGPPVGETAG-LPPSSNVSNKRLQQTQAQVDEIVDIMKSNVDKVLERDQKL 195
M+A + TVP P GE PP + SN+RLQQTQAQVDE+VDIM+ NVDKVLERDQKL
Sbjct: 1 MSATAATVPPAAPAGEGGPPAPPPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKL 60
Query: 196 SELDNRAEALQAGASQFEASAGKLKRKFWLKNLK 297
SELD+RA+ALQAGASQFE SA KLKRK+W KNLK
Sbjct: 61 SELDDRADALQAGASQFETSAAKLKRKYWWKNLK 94
>sp|P63026|VAMP2_BOVIN Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
sp|P63027|VAM2_HUMAN Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin 2)
Length = 116
Score = 127 bits (319), Expect = 4e-29
Identities = 66/94 (70%), Positives = 75/94 (79%), Gaps = 1/94 (1%)
Frame = +1
Query: 19 MAANSQTVPGGPPVGETAG-LPPSSNVSNKRLQQTQAQVDEIVDIMKSNVDKVLERDQKL 195
M+A + T P P GE PP + SN+RLQQTQAQVDE+VDIM+ NVDKVLERDQKL
Sbjct: 1 MSATAATAPPAAPAGEGGPPAPPPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKL 60
Query: 196 SELDNRAEALQAGASQFEASAGKLKRKFWLKNLK 297
SELD+RA+ALQAGASQFE SA KLKRK+W KNLK
Sbjct: 61 SELDDRADALQAGASQFETSAAKLKRKYWWKNLK 94
>sp|P23763|VAM1_HUMAN Vesicle-associated membrane protein 1 (VAMP-1) (Synaptobrevin 1)
Length = 118
Score = 122 bits (305), Expect = 2e-27
Identities = 62/87 (71%), Positives = 72/87 (82%)
Frame = +1
Query: 37 TVPGGPPVGETAGLPPSSNVSNKRLQQTQAQVDEIVDIMKSNVDKVLERDQKLSELDNRA 216
T PGG P G PP + SN+RLQQTQAQV+E+VDI++ NVDKVLERDQKLSELD+RA
Sbjct: 15 TAPGGGPPG-----PPPNMTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQKLSELDDRA 69
Query: 217 EALQAGASQFEASAGKLKRKFWLKNLK 297
+ALQAGASQFE+SA KLKRK+W KN K
Sbjct: 70 DALQAGASQFESSAAKLKRKYWWKNCK 96
>sp|P47194|SYB_LOLPE Synaptobrevin
Length = 125
Score = 122 bits (305), Expect = 2e-27
Identities = 66/98 (67%), Positives = 74/98 (75%), Gaps = 8/98 (8%)
Frame = +1
Query: 28 NSQTVPGGPPVG--ETAGL------PPSSNVSNKRLQQTQAQVDEIVDIMKSNVDKVLER 183
N Q PGGPP G + G PP +KRLQQTQAQV+E+VDIM+ NVDKVLER
Sbjct: 6 NPQAGPGGPPSGPPQPGGPPGPPQGPPQPVQQSKRLQQTQAQVEEVVDIMRVNVDKVLER 65
Query: 184 DQKLSELDNRAEALQAGASQFEASAGKLKRKFWLKNLK 297
D K+SELD+RA+ALQAGASQFEASAGKLKRKFW KN K
Sbjct: 66 DSKISELDDRADALQAGASQFEASAGKLKRKFWWKNCK 103
>sp|Q62442|VAMP1_MOUSE Vesicle-associated membrane protein 1 (VAMP-1) (Synaptobrevin-1)
Length = 118
Score = 121 bits (304), Expect = 2e-27
Identities = 62/85 (72%), Positives = 71/85 (83%)
Frame = +1
Query: 43 PGGPPVGETAGLPPSSNVSNKRLQQTQAQVDEIVDIMKSNVDKVLERDQKLSELDNRAEA 222
PGG P G PP + SN+RLQQTQAQV+E+VDIM+ NVDKVLERDQKLSELD+RA+A
Sbjct: 17 PGGGPPG-----PPPNMTSNRRLQQTQAQVEEVVDIMRVNVDKVLERDQKLSELDDRADA 71
Query: 223 LQAGASQFEASAGKLKRKFWLKNLK 297
LQAGASQFE+SA KLKRK+W KN K
Sbjct: 72 LQAGASQFESSAAKLKRKYWWKNCK 96
>sp|Q63666|VAMP1_RAT Vesicle-associated membrane protein 1 (VAMP-1) (Synaptobrevin-1)
Length = 118
Score = 118 bits (295), Expect = 2e-26
Identities = 60/85 (70%), Positives = 70/85 (82%)
Frame = +1
Query: 43 PGGPPVGETAGLPPSSNVSNKRLQQTQAQVDEIVDIMKSNVDKVLERDQKLSELDNRAEA 222
PGG P G PP + SN+RLQQTQAQV+E+VDI++ NVDKVLERDQKLSELD+RA+A
Sbjct: 17 PGGGPPG-----PPPNTTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQKLSELDDRADA 71
Query: 223 LQAGASQFEASAGKLKRKFWLKNLK 297
LQAGAS FE+SA KLKRK+W KN K
Sbjct: 72 LQAGASVFESSAAKLKRKYWWKNCK 96
>sp|P47193|VAMP2_XENLA Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
(SYBII)
Length = 114
Score = 117 bits (294), Expect = 3e-26
Identities = 61/86 (70%), Positives = 70/86 (81%), Gaps = 3/86 (3%)
Frame = +1
Query: 49 GPPV---GETAGLPPSSNVSNKRLQQTQAQVDEIVDIMKSNVDKVLERDQKLSELDNRAE 219
GPP G+ A P + SN+RLQQTQAQVDE+VDIM+ NVDKVLERD KLSELD+RA+
Sbjct: 7 GPPAAAPGDGAPQGPPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDTKLSELDDRAD 66
Query: 220 ALQAGASQFEASAGKLKRKFWLKNLK 297
ALQAGASQFE SA KLKRK+W KN+K
Sbjct: 67 ALQAGASQFETSAAKLKRKYWWKNMK 92
>sp|P13701|SYB_TORCA Synaptobrevin (Synaptic vesicle-associated integral membrane
protein) (VAMP-1)
Length = 120
Score = 117 bits (294), Expect = 3e-26
Identities = 61/85 (71%), Positives = 72/85 (84%)
Frame = +1
Query: 43 PGGPPVGETAGLPPSSNVSNKRLQQTQAQVDEIVDIMKSNVDKVLERDQKLSELDNRAEA 222
P GPP G PP++ SN+RLQQTQAQV+E+VDI++ NVDKVLERDQKLSELD+RA+A
Sbjct: 20 PTGPP-----GAPPNTT-SNRRLQQTQAQVEEVVDIIRVNVDKVLERDQKLSELDDRADA 73
Query: 223 LQAGASQFEASAGKLKRKFWLKNLK 297
LQAGASQFE+SA KLKRK+W KN K
Sbjct: 74 LQAGASQFESSAAKLKRKYWWKNCK 98
>sp|P35589|SYB_APLCA Synaptobrevin
Length = 180
Score = 115 bits (289), Expect = 1e-25
Identities = 61/85 (71%), Positives = 70/85 (82%)
Frame = +1
Query: 43 PGGPPVGETAGLPPSSNVSNKRLQQTQAQVDEIVDIMKSNVDKVLERDQKLSELDNRAEA 222
PGGP G PP +KRLQQTQAQVDE+VDIM+ NV+KVL+RDQK+S+LD+RAEA
Sbjct: 5 PGGPQGGMQ---PpreQ--SKRLQQTQAQVDEVVDIMRVNVEKVLDRDQKISQLDDRAEA 59
Query: 223 LQAGASQFEASAGKLKRKFWLKNLK 297
LQAGASQFEASAGKLKRK+W KN K
Sbjct: 60 LQAGASQFEASAGKLKRKYWWKNCK 84
>sp|Q15836|VAM3_HUMAN Vesicle-associated membrane protein 3 (VAMP-3) (Synaptobrevin 3)
(Cellubrevin) (CEB)
Length = 100
Score = 113 bits (282), Expect = 7e-25
Identities = 56/73 (76%), Positives = 64/73 (87%)
Frame = +1
Query: 79 PPSSNVSNKRLQQTQAQVDEIVDIMKSNVDKVLERDQKLSELDNRAEALQAGASQFEASA 258
P ++ SN+RLQQTQ QVDE+VDIM+ NVDKVLERDQKLSELD+RA+ALQAGASQFE SA
Sbjct: 5 PTAATGSNRRLQQTQNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSA 64
Query: 259 GKLKRKFWLKNLK 297
KLKRK+W KN K
Sbjct: 65 AKLKRKYWWKNCK 77
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,355,867
Number of Sequences: 369166
Number of extensions: 1180728
Number of successful extensions: 3389
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3250
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3383
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7956112725
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)