Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_021_D07 (825 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P63045|VAMP2_RAT Vesicle-associated membrane protein 2 (... 129 1e-29 sp|P63026|VAMP2_BOVIN Vesicle-associated membrane protein 2... 127 4e-29 sp|P23763|VAM1_HUMAN Vesicle-associated membrane protein 1 ... 122 2e-27 sp|P47194|SYB_LOLPE Synaptobrevin 122 2e-27 sp|Q62442|VAMP1_MOUSE Vesicle-associated membrane protein 1... 121 2e-27 sp|Q63666|VAMP1_RAT Vesicle-associated membrane protein 1 (... 118 2e-26 sp|P47193|VAMP2_XENLA Vesicle-associated membrane protein 2... 117 3e-26 sp|P13701|SYB_TORCA Synaptobrevin (Synaptic vesicle-associa... 117 3e-26 sp|P35589|SYB_APLCA Synaptobrevin 115 1e-25 sp|Q15836|VAM3_HUMAN Vesicle-associated membrane protein 3 ... 113 7e-25
>sp|P63045|VAMP2_RAT Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2) sp|P63044|VAMP2_MOUSE Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2) Length = 116 Score = 129 bits (323), Expect = 1e-29 Identities = 67/94 (71%), Positives = 76/94 (80%), Gaps = 1/94 (1%) Frame = +1 Query: 19 MAANSQTVPGGPPVGETAG-LPPSSNVSNKRLQQTQAQVDEIVDIMKSNVDKVLERDQKL 195 M+A + TVP P GE PP + SN+RLQQTQAQVDE+VDIM+ NVDKVLERDQKL Sbjct: 1 MSATAATVPPAAPAGEGGPPAPPPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKL 60 Query: 196 SELDNRAEALQAGASQFEASAGKLKRKFWLKNLK 297 SELD+RA+ALQAGASQFE SA KLKRK+W KNLK Sbjct: 61 SELDDRADALQAGASQFETSAAKLKRKYWWKNLK 94
>sp|P63026|VAMP2_BOVIN Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2) sp|P63027|VAM2_HUMAN Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin 2) Length = 116 Score = 127 bits (319), Expect = 4e-29 Identities = 66/94 (70%), Positives = 75/94 (79%), Gaps = 1/94 (1%) Frame = +1 Query: 19 MAANSQTVPGGPPVGETAG-LPPSSNVSNKRLQQTQAQVDEIVDIMKSNVDKVLERDQKL 195 M+A + T P P GE PP + SN+RLQQTQAQVDE+VDIM+ NVDKVLERDQKL Sbjct: 1 MSATAATAPPAAPAGEGGPPAPPPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKL 60 Query: 196 SELDNRAEALQAGASQFEASAGKLKRKFWLKNLK 297 SELD+RA+ALQAGASQFE SA KLKRK+W KNLK Sbjct: 61 SELDDRADALQAGASQFETSAAKLKRKYWWKNLK 94
>sp|P23763|VAM1_HUMAN Vesicle-associated membrane protein 1 (VAMP-1) (Synaptobrevin 1) Length = 118 Score = 122 bits (305), Expect = 2e-27 Identities = 62/87 (71%), Positives = 72/87 (82%) Frame = +1 Query: 37 TVPGGPPVGETAGLPPSSNVSNKRLQQTQAQVDEIVDIMKSNVDKVLERDQKLSELDNRA 216 T PGG P G PP + SN+RLQQTQAQV+E+VDI++ NVDKVLERDQKLSELD+RA Sbjct: 15 TAPGGGPPG-----PPPNMTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQKLSELDDRA 69 Query: 217 EALQAGASQFEASAGKLKRKFWLKNLK 297 +ALQAGASQFE+SA KLKRK+W KN K Sbjct: 70 DALQAGASQFESSAAKLKRKYWWKNCK 96
>sp|P47194|SYB_LOLPE Synaptobrevin Length = 125 Score = 122 bits (305), Expect = 2e-27 Identities = 66/98 (67%), Positives = 74/98 (75%), Gaps = 8/98 (8%) Frame = +1 Query: 28 NSQTVPGGPPVG--ETAGL------PPSSNVSNKRLQQTQAQVDEIVDIMKSNVDKVLER 183 N Q PGGPP G + G PP +KRLQQTQAQV+E+VDIM+ NVDKVLER Sbjct: 6 NPQAGPGGPPSGPPQPGGPPGPPQGPPQPVQQSKRLQQTQAQVEEVVDIMRVNVDKVLER 65 Query: 184 DQKLSELDNRAEALQAGASQFEASAGKLKRKFWLKNLK 297 D K+SELD+RA+ALQAGASQFEASAGKLKRKFW KN K Sbjct: 66 DSKISELDDRADALQAGASQFEASAGKLKRKFWWKNCK 103
>sp|Q62442|VAMP1_MOUSE Vesicle-associated membrane protein 1 (VAMP-1) (Synaptobrevin-1) Length = 118 Score = 121 bits (304), Expect = 2e-27 Identities = 62/85 (72%), Positives = 71/85 (83%) Frame = +1 Query: 43 PGGPPVGETAGLPPSSNVSNKRLQQTQAQVDEIVDIMKSNVDKVLERDQKLSELDNRAEA 222 PGG P G PP + SN+RLQQTQAQV+E+VDIM+ NVDKVLERDQKLSELD+RA+A Sbjct: 17 PGGGPPG-----PPPNMTSNRRLQQTQAQVEEVVDIMRVNVDKVLERDQKLSELDDRADA 71 Query: 223 LQAGASQFEASAGKLKRKFWLKNLK 297 LQAGASQFE+SA KLKRK+W KN K Sbjct: 72 LQAGASQFESSAAKLKRKYWWKNCK 96
>sp|Q63666|VAMP1_RAT Vesicle-associated membrane protein 1 (VAMP-1) (Synaptobrevin-1) Length = 118 Score = 118 bits (295), Expect = 2e-26 Identities = 60/85 (70%), Positives = 70/85 (82%) Frame = +1 Query: 43 PGGPPVGETAGLPPSSNVSNKRLQQTQAQVDEIVDIMKSNVDKVLERDQKLSELDNRAEA 222 PGG P G PP + SN+RLQQTQAQV+E+VDI++ NVDKVLERDQKLSELD+RA+A Sbjct: 17 PGGGPPG-----PPPNTTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQKLSELDDRADA 71 Query: 223 LQAGASQFEASAGKLKRKFWLKNLK 297 LQAGAS FE+SA KLKRK+W KN K Sbjct: 72 LQAGASVFESSAAKLKRKYWWKNCK 96
>sp|P47193|VAMP2_XENLA Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2) (SYBII) Length = 114 Score = 117 bits (294), Expect = 3e-26 Identities = 61/86 (70%), Positives = 70/86 (81%), Gaps = 3/86 (3%) Frame = +1 Query: 49 GPPV---GETAGLPPSSNVSNKRLQQTQAQVDEIVDIMKSNVDKVLERDQKLSELDNRAE 219 GPP G+ A P + SN+RLQQTQAQVDE+VDIM+ NVDKVLERD KLSELD+RA+ Sbjct: 7 GPPAAAPGDGAPQGPPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDTKLSELDDRAD 66 Query: 220 ALQAGASQFEASAGKLKRKFWLKNLK 297 ALQAGASQFE SA KLKRK+W KN+K Sbjct: 67 ALQAGASQFETSAAKLKRKYWWKNMK 92
>sp|P13701|SYB_TORCA Synaptobrevin (Synaptic vesicle-associated integral membrane protein) (VAMP-1) Length = 120 Score = 117 bits (294), Expect = 3e-26 Identities = 61/85 (71%), Positives = 72/85 (84%) Frame = +1 Query: 43 PGGPPVGETAGLPPSSNVSNKRLQQTQAQVDEIVDIMKSNVDKVLERDQKLSELDNRAEA 222 P GPP G PP++ SN+RLQQTQAQV+E+VDI++ NVDKVLERDQKLSELD+RA+A Sbjct: 20 PTGPP-----GAPPNTT-SNRRLQQTQAQVEEVVDIIRVNVDKVLERDQKLSELDDRADA 73 Query: 223 LQAGASQFEASAGKLKRKFWLKNLK 297 LQAGASQFE+SA KLKRK+W KN K Sbjct: 74 LQAGASQFESSAAKLKRKYWWKNCK 98
>sp|P35589|SYB_APLCA Synaptobrevin Length = 180 Score = 115 bits (289), Expect = 1e-25 Identities = 61/85 (71%), Positives = 70/85 (82%) Frame = +1 Query: 43 PGGPPVGETAGLPPSSNVSNKRLQQTQAQVDEIVDIMKSNVDKVLERDQKLSELDNRAEA 222 PGGP G PP +KRLQQTQAQVDE+VDIM+ NV+KVL+RDQK+S+LD+RAEA Sbjct: 5 PGGPQGGMQ---PpreQ--SKRLQQTQAQVDEVVDIMRVNVEKVLDRDQKISQLDDRAEA 59 Query: 223 LQAGASQFEASAGKLKRKFWLKNLK 297 LQAGASQFEASAGKLKRK+W KN K Sbjct: 60 LQAGASQFEASAGKLKRKYWWKNCK 84
>sp|Q15836|VAM3_HUMAN Vesicle-associated membrane protein 3 (VAMP-3) (Synaptobrevin 3) (Cellubrevin) (CEB) Length = 100 Score = 113 bits (282), Expect = 7e-25 Identities = 56/73 (76%), Positives = 64/73 (87%) Frame = +1 Query: 79 PPSSNVSNKRLQQTQAQVDEIVDIMKSNVDKVLERDQKLSELDNRAEALQAGASQFEASA 258 P ++ SN+RLQQTQ QVDE+VDIM+ NVDKVLERDQKLSELD+RA+ALQAGASQFE SA Sbjct: 5 PTAATGSNRRLQQTQNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSA 64 Query: 259 GKLKRKFWLKNLK 297 KLKRK+W KN K Sbjct: 65 AKLKRKYWWKNCK 77
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 72,355,867 Number of Sequences: 369166 Number of extensions: 1180728 Number of successful extensions: 3389 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3250 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3383 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 7956112725 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)