Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_021_C01
(706 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q90705|EF2_CHICK Elongation factor 2 (EF-2) 360 3e-99
sp|P58252|EF2_MOUSE Elongation factor 2 (EF-2) 357 1e-98
sp|P13639|EF2_HUMAN Elongation factor 2 (EF-2) 357 1e-98
sp|P05086|EF2_MESAU Elongation factor 2 (EF-2) 357 1e-98
sp|P05197|EF2_RAT Elongation factor 2 (EF-2) 357 1e-98
sp|P29691|EF2_CAEEL Elongation factor 2 (EF-2) 354 1e-97
sp|P09445|EF2_CRIGR Elongation factor 2 (EF-2) 351 1e-96
sp|P13060|EF2_DROME Elongation factor 2 (EF-2) 348 1e-95
sp|Q6BJ25|EF2_DEBHA Elongation factor 2 (EF-2) 306 5e-83
sp|O23755|EF2_BETVU Elongation factor 2 (EF-2) 301 9e-82
>sp|Q90705|EF2_CHICK Elongation factor 2 (EF-2)
Length = 858
Score = 360 bits (923), Expect = 3e-99
Identities = 163/220 (74%), Positives = 187/220 (85%)
Frame = +2
Query: 11 YDWDVTESRKIWCFGPDGNGPNLVVDVSKGVQYLNEIKDSVVAAFNWATKDGVLCEENMR 190
Y+WDVTE+RKIWCFGPDG GPN++ D++KGVQYLNEIKDSVVA F WATK+GVLCEENMR
Sbjct: 639 YEWDVTEARKIWCFGPDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGVLCEENMR 698
Query: 191 GVRFNIHDVTLHADAIHRGGGQIIPTARRCFYASVLTASPCLLEPVYQCEIQGPETALGG 370
GVRF++HDVTLHADAIHRGGGQIIPTARRC YA VLTA P L+EP+Y EIQ PE +GG
Sbjct: 699 GVRFDVHDVTLHADAIHRGGGQIIPTARRCLYACVLTAQPRLMEPIYLVEIQCPEQVVGG 758
Query: 371 IYSTLNKRRGIIFSEMQVAGTPQYVVKAYLPVNESFNFTSELRAQTGGQAFPQCVFDHWQ 550
IY LN++RG +F E QVAGTP +VVKAYLPVNESF FT++LR+ TGGQAFPQCVFDHWQ
Sbjct: 759 IYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQ 818
Query: 551 LFPGNPLDPLSKPGITVKDTRKRKGLSEDVPLLDKFLDKL 670
+ PG+P D S+P V +TRKRKGL E +P LD FLDKL
Sbjct: 819 ILPGDPFDSASRPSQVVAETRKRKGLKEGIPALDNFLDKL 858
>sp|P58252|EF2_MOUSE Elongation factor 2 (EF-2)
Length = 858
Score = 357 bits (917), Expect = 1e-98
Identities = 162/220 (73%), Positives = 186/220 (84%)
Frame = +2
Query: 11 YDWDVTESRKIWCFGPDGNGPNLVVDVSKGVQYLNEIKDSVVAAFNWATKDGVLCEENMR 190
Y+WDV E+RKIWCFGPDG GPN++ D++KGVQYLNEIKDSVVA F WATK+G LCEENMR
Sbjct: 639 YEWDVAEARKIWCFGPDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMR 698
Query: 191 GVRFNIHDVTLHADAIHRGGGQIIPTARRCFYASVLTASPCLLEPVYQCEIQGPETALGG 370
GVRF++HDVTLHADAIHRGGGQIIPTARRC YASVLTA P L+EP+Y EIQ PE +GG
Sbjct: 699 GVRFDVHDVTLHADAIHRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGG 758
Query: 371 IYSTLNKRRGIIFSEMQVAGTPQYVVKAYLPVNESFNFTSELRAQTGGQAFPQCVFDHWQ 550
IY LN++RG +F E QVAGTP +VVKAYLPVNESF FT++LR+ TGGQAFPQCVFDHWQ
Sbjct: 759 IYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQ 818
Query: 551 LFPGNPLDPLSKPGITVKDTRKRKGLSEDVPLLDKFLDKL 670
+ PG+P D S+P V +TRKRKGL E +P LD FLDKL
Sbjct: 819 ILPGDPFDNSSRPSQVVAETRKRKGLKEGIPALDNFLDKL 858
>sp|P13639|EF2_HUMAN Elongation factor 2 (EF-2)
Length = 858
Score = 357 bits (917), Expect = 1e-98
Identities = 162/220 (73%), Positives = 186/220 (84%)
Frame = +2
Query: 11 YDWDVTESRKIWCFGPDGNGPNLVVDVSKGVQYLNEIKDSVVAAFNWATKDGVLCEENMR 190
Y+WDV E+RKIWCFGPDG GPN++ D++KGVQYLNEIKDSVVA F WATK+G LCEENMR
Sbjct: 639 YEWDVAEARKIWCFGPDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMR 698
Query: 191 GVRFNIHDVTLHADAIHRGGGQIIPTARRCFYASVLTASPCLLEPVYQCEIQGPETALGG 370
GVRF++HDVTLHADAIHRGGGQIIPTARRC YASVLTA P L+EP+Y EIQ PE +GG
Sbjct: 699 GVRFDVHDVTLHADAIHRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGG 758
Query: 371 IYSTLNKRRGIIFSEMQVAGTPQYVVKAYLPVNESFNFTSELRAQTGGQAFPQCVFDHWQ 550
IY LN++RG +F E QVAGTP +VVKAYLPVNESF FT++LR+ TGGQAFPQCVFDHWQ
Sbjct: 759 IYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQ 818
Query: 551 LFPGNPLDPLSKPGITVKDTRKRKGLSEDVPLLDKFLDKL 670
+ PG+P D S+P V +TRKRKGL E +P LD FLDKL
Sbjct: 819 ILPGDPFDNSSRPSQVVAETRKRKGLKEGIPALDNFLDKL 858
>sp|P05086|EF2_MESAU Elongation factor 2 (EF-2)
Length = 858
Score = 357 bits (917), Expect = 1e-98
Identities = 162/220 (73%), Positives = 186/220 (84%)
Frame = +2
Query: 11 YDWDVTESRKIWCFGPDGNGPNLVVDVSKGVQYLNEIKDSVVAAFNWATKDGVLCEENMR 190
Y+WDV E+RKIWCFGPDG GPN++ D++KGVQYLNEIKDSVVA F WATK+G LCEENMR
Sbjct: 639 YEWDVAEARKIWCFGPDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMR 698
Query: 191 GVRFNIHDVTLHADAIHRGGGQIIPTARRCFYASVLTASPCLLEPVYQCEIQGPETALGG 370
GVRF++HDVTLHADAIHRGGGQIIPTARRC YASVLTA P L+EP+Y EIQ PE +GG
Sbjct: 699 GVRFDVHDVTLHADAIHRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGG 758
Query: 371 IYSTLNKRRGIIFSEMQVAGTPQYVVKAYLPVNESFNFTSELRAQTGGQAFPQCVFDHWQ 550
IY LN++RG +F E QVAGTP +VVKAYLPVNESF FT++LR+ TGGQAFPQCVFDHWQ
Sbjct: 759 IYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQ 818
Query: 551 LFPGNPLDPLSKPGITVKDTRKRKGLSEDVPLLDKFLDKL 670
+ PG+P D S+P V +TRKRKGL E +P LD FLDKL
Sbjct: 819 ILPGDPFDNSSRPSQVVAETRKRKGLKEGIPALDNFLDKL 858
>sp|P05197|EF2_RAT Elongation factor 2 (EF-2)
Length = 858
Score = 357 bits (917), Expect = 1e-98
Identities = 162/220 (73%), Positives = 186/220 (84%)
Frame = +2
Query: 11 YDWDVTESRKIWCFGPDGNGPNLVVDVSKGVQYLNEIKDSVVAAFNWATKDGVLCEENMR 190
Y+WDV E+RKIWCFGPDG GPN++ D++KGVQYLNEIKDSVVA F WATK+G LCEENMR
Sbjct: 639 YEWDVAEARKIWCFGPDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMR 698
Query: 191 GVRFNIHDVTLHADAIHRGGGQIIPTARRCFYASVLTASPCLLEPVYQCEIQGPETALGG 370
GVRF++HDVTLHADAIHRGGGQIIPTARRC YASVLTA P L+EP+Y EIQ PE +GG
Sbjct: 699 GVRFDVHDVTLHADAIHRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGG 758
Query: 371 IYSTLNKRRGIIFSEMQVAGTPQYVVKAYLPVNESFNFTSELRAQTGGQAFPQCVFDHWQ 550
IY LN++RG +F E QVAGTP +VVKAYLPVNESF FT++LR+ TGGQAFPQCVFDHWQ
Sbjct: 759 IYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQ 818
Query: 551 LFPGNPLDPLSKPGITVKDTRKRKGLSEDVPLLDKFLDKL 670
+ PG+P D S+P V +TRKRKGL E +P LD FLDKL
Sbjct: 819 ILPGDPFDNSSRPSQVVAETRKRKGLKEGIPALDNFLDKL 858
>sp|P29691|EF2_CAEEL Elongation factor 2 (EF-2)
Length = 852
Score = 354 bits (909), Expect = 1e-97
Identities = 166/220 (75%), Positives = 189/220 (85%)
Frame = +2
Query: 11 YDWDVTESRKIWCFGPDGNGPNLVVDVSKGVQYLNEIKDSVVAAFNWATKDGVLCEENMR 190
Y++DVTE+RKIWCFGPDG GPNL++DV+KGVQYLNEIKDSVVA F WAT++GVL +ENMR
Sbjct: 633 YEYDVTEARKIWCFGPDGTGPNLLMDVTKGVQYLNEIKDSVVAGFQWATREGVLSDENMR 692
Query: 191 GVRFNIHDVTLHADAIHRGGGQIIPTARRCFYASVLTASPCLLEPVYQCEIQGPETALGG 370
GVRFN+HDVTLHADAIHRGGGQIIPTARR FYASVLTA P LLEPVY EIQ PE A+GG
Sbjct: 693 GVRFNVHDVTLHADAIHRGGGQIIPTARRVFYASVLTAEPRLLEPVYLVEIQCPEAAVGG 752
Query: 371 IYSTLNKRRGIIFSEMQVAGTPQYVVKAYLPVNESFNFTSELRAQTGGQAFPQCVFDHWQ 550
IY LN+RRG +F E QV GTP +VVKAYLPVNESF FT++LR+ TGGQAFPQCVFDHWQ
Sbjct: 753 IYGVLNRRRGHVFEESQVTGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQ 812
Query: 551 LFPGNPLDPLSKPGITVKDTRKRKGLSEDVPLLDKFLDKL 670
+ PG+PL+ +KP V DTRKRKGL E VP LD +LDK+
Sbjct: 813 VLPGDPLEAGTKPNQIVLDTRKRKGLKEGVPALDNYLDKM 852
>sp|P09445|EF2_CRIGR Elongation factor 2 (EF-2)
Length = 858
Score = 351 bits (900), Expect = 1e-96
Identities = 160/220 (72%), Positives = 184/220 (83%)
Frame = +2
Query: 11 YDWDVTESRKIWCFGPDGNGPNLVVDVSKGVQYLNEIKDSVVAAFNWATKDGVLCEENMR 190
Y+WDV E+RKIWCFGPDG GPN++ D++KGVQYLNEIKDSVVA F WATK+G LCEENMR
Sbjct: 639 YEWDVAEARKIWCFGPDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMR 698
Query: 191 GVRFNIHDVTLHADAIHRGGGQIIPTARRCFYASVLTASPCLLEPVYQCEIQGPETALGG 370
GVRF++HDVTLHADAIHR GGQIIPTARRC YASVLTA P L+EP+Y EIQ PE +GG
Sbjct: 699 GVRFDVHDVTLHADAIHRRGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGG 758
Query: 371 IYSTLNKRRGIIFSEMQVAGTPQYVVKAYLPVNESFNFTSELRAQTGGQAFPQCVFDHWQ 550
IY LN++RG +F E QVAGTP +VVKAYLPVNESF FT++LR+ TGGQAFPQCVFDHWQ
Sbjct: 759 IYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQ 818
Query: 551 LFPGNPLDPLSKPGITVKDTRKRKGLSEDVPLLDKFLDKL 670
+ PG+P D S+ V +TRKRKGL E +P LD FLDKL
Sbjct: 819 ILPGDPFDNSSRGSQVVAETRKRKGLKEGIPALDNFLDKL 858
>sp|P13060|EF2_DROME Elongation factor 2 (EF-2)
Length = 844
Score = 348 bits (892), Expect = 1e-95
Identities = 159/223 (71%), Positives = 187/223 (83%)
Frame = +2
Query: 2 SRTYDWDVTESRKIWCFGPDGNGPNLVVDVSKGVQYLNEIKDSVVAAFNWATKDGVLCEE 181
S YD+DVTE+RKIWCFGPDG GPN ++D +K VQYLNEIKDSVVA F WA+K+G+L +E
Sbjct: 622 SEKYDYDVTEARKIWCFGPDGTGPNFILDCTKSVQYLNEIKDSVVAGFQWASKEGILADE 681
Query: 182 NMRGVRFNIHDVTLHADAIHRGGGQIIPTARRCFYASVLTASPCLLEPVYQCEIQGPETA 361
N+RGVRFNI+DVTLHADAIHRGGGQIIPT RRC YA+ +TA P L+EPVY CEIQ PE A
Sbjct: 682 NLRGVRFNIYDVTLHADAIHRGGGQIIPTTRRCLYAAAITAKPRLMEPVYLCEIQCPEVA 741
Query: 362 LGGIYSTLNKRRGIIFSEMQVAGTPQYVVKAYLPVNESFNFTSELRAQTGGQAFPQCVFD 541
+GGIY LN+RRG +F E QV GTP +VVKAYLPVNESF FT++LR+ TGGQAFPQCVFD
Sbjct: 742 VGGIYGVLNRRRGHVFEENQVVGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFD 801
Query: 542 HWQLFPGNPLDPLSKPGITVKDTRKRKGLSEDVPLLDKFLDKL 670
HWQ+ PG+P +P SKP V+DTRKRKGL E +P L ++LDKL
Sbjct: 802 HWQVLPGDPSEPSSKPYAIVQDTRKRKGLKEGLPDLSQYLDKL 844
>sp|Q6BJ25|EF2_DEBHA Elongation factor 2 (EF-2)
Length = 842
Score = 306 bits (783), Expect = 5e-83
Identities = 147/220 (66%), Positives = 171/220 (77%)
Frame = +2
Query: 11 YDWDVTESRKIWCFGPDGNGPNLVVDVSKGVQYLNEIKDSVVAAFNWATKDGVLCEENMR 190
+ WDVT++RKIWCFGPDGNGPNLVVD +K VQYLNEIKDSVVAAF WATK+G + EN+R
Sbjct: 623 HGWDVTDARKIWCFGPDGNGPNLVVDQTKAVQYLNEIKDSVVAAFQWATKEGPIFGENVR 682
Query: 191 GVRFNIHDVTLHADAIHRGGGQIIPTARRCFYASVLTASPCLLEPVYQCEIQGPETALGG 370
VR NI DVTLHADAIHRGGGQIIPT RR YAS+L A P + EPV+ EIQ PE A+GG
Sbjct: 683 SVRVNILDVTLHADAIHRGGGQIIPTMRRVTYASMLLAEPAIQEPVFLVEIQCPENAIGG 742
Query: 371 IYSTLNKRRGIIFSEMQVAGTPQYVVKAYLPVNESFNFTSELRAQTGGQAFPQCVFDHWQ 550
IYS LNK+RG + SE Q GTP + VKAYLPVNESF F+ ELR TGGQAFPQ +FDHW
Sbjct: 743 IYSVLNKKRGQVISEEQRPGTPLFTVKAYLPVNESFGFSGELRQSTGGQAFPQLIFDHWA 802
Query: 551 LFPGNPLDPLSKPGITVKDTRKRKGLSEDVPLLDKFLDKL 670
G+P DP SK G VK+ R+R+G+ DVP +++ DKL
Sbjct: 803 NLNGDPTDPTSKVGTIVKEKRERQGMKPDVPGYEEYYDKL 842
>sp|O23755|EF2_BETVU Elongation factor 2 (EF-2)
Length = 843
Score = 301 bits (772), Expect = 9e-82
Identities = 146/220 (66%), Positives = 167/220 (75%)
Frame = +2
Query: 11 YDWDVTESRKIWCFGPDGNGPNLVVDVSKGVQYLNEIKDSVVAAFNWATKDGVLCEENMR 190
Y WD ++KIWCFGP+ GPN+VVD+ KGVQYLNEIKDSVVA F WA+K+G L EENMR
Sbjct: 624 YGWDKDLAKKIWCFGPETTGPNMVVDMCKGVQYLNEIKDSVVAGFQWASKEGALAEENMR 683
Query: 191 GVRFNIHDVTLHADAIHRGGGQIIPTARRCFYASVLTASPCLLEPVYQCEIQGPETALGG 370
G+ F + DV LH DAIHRGGGQIIPTARR FYAS LTA P LLEPVY EIQ PE ALGG
Sbjct: 684 GICFEVCDVVLHTDAIHRGGGQIIPTARRVFYASQLTAKPRLLEPVYLVEIQAPENALGG 743
Query: 371 IYSTLNKRRGIIFSEMQVAGTPQYVVKAYLPVNESFNFTSELRAQTGGQAFPQCVFDHWQ 550
IYS LN++RG +F EMQ GTP Y +KAYLPV ESF F+S LRA T GQAFPQCVFDHW+
Sbjct: 744 IYSVLNQKRGHVFEEMQRPGTPLYNIKAYLPVVESFGFSSTLRASTSGQAFPQCVFDHWE 803
Query: 551 LFPGNPLDPLSKPGITVKDTRKRKGLSEDVPLLDKFLDKL 670
+ P +PL+ S+ V RKRKGL E + L +F DKL
Sbjct: 804 MMPSDPLEAGSQASTLVSVIRKRKGLKEQMTPLSEFEDKL 843
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,306,798
Number of Sequences: 369166
Number of extensions: 1910256
Number of successful extensions: 4870
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4571
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4737
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6170718545
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)