Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_021_B15
(603 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q61879|MYH10_MOUSE Myosin-10 (Myosin heavy chain, nonmus... 81 2e-15
sp|P35580|MYH10_HUMAN Myosin-10 (Myosin heavy chain, nonmus... 81 2e-15
sp|Q8VDD5|MYH9_MOUSE Myosin-9 (Myosin heavy chain, nonmuscl... 81 2e-15
sp|Q9JLT0|MYH10_RAT Myosin-10 (Myosin heavy chain, nonmuscl... 81 2e-15
sp|Q62812|MYH9_RAT Myosin-9 (Myosin heavy chain, nonmuscle ... 81 2e-15
sp|Q27991|MYH10_BOVIN Myosin-10 (Myosin heavy chain, nonmus... 81 2e-15
sp|Q99105|MYSU_RABIT Myosin heavy chain, embryonic smooth m... 81 2e-15
sp|P35749|MYH11_HUMAN Myosin-11 (Myosin heavy chain, smooth... 80 3e-15
sp|P35579|MYH9_HUMAN Myosin-9 (Myosin heavy chain, nonmuscl... 80 5e-15
sp|P10587|MYH11_CHICK Myosin-11 (Myosin heavy chain, gizzar... 80 5e-15
>sp|Q61879|MYH10_MOUSE Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy
chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin
heavy chain, type B) (Nonmuscle myosin heavy chain-B)
(NMMHC-B)
Length = 1976
Score = 80.9 bits (198), Expect = 2e-15
Identities = 45/134 (33%), Positives = 70/134 (52%)
Frame = +1
Query: 1 LHEKIEELEVETGKKYKATVSAQQIKIQSLDAQLDAKIEEINQAXXXXXXXXXXXXXIMA 180
L K++ELE K+KAT+SA + KI L+ QL+ + +E A I
Sbjct: 1797 LKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFM 1856
Query: 181 LMVDEQRRADNAIEQIEKATGRYKKAERSLQMEQENNSALTTQNRRLQRDLEEVNETKEA 360
+ DE+R AD EQ+EKA R K+ +R L+ +E + R+LQR+L++ E E
Sbjct: 1857 QVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEG 1916
Query: 361 RDQEIKVLKTKVER 402
+E+ LK ++ R
Sbjct: 1917 LSREVSTLKNRLRR 1930
Score = 37.0 bits (84), Expect = 0.039
Identities = 39/179 (21%), Positives = 80/179 (44%), Gaps = 21/179 (11%)
Frame = +1
Query: 1 LHEKIEELEVETGKKYKATVSAQQIKIQSLDAQLDAK---IEEINQAXXXXXXXXXXXXX 171
L +++EE +V K + T + Q ++ L LD + + + +
Sbjct: 1404 LSQRLEE-KVLAYDKLEKTKNRLQQELDDLTVDLDHQRQIVSNLEKKQKKFDQLLAEEKG 1462
Query: 172 IMALMVDEQRRAD-NAIEQIEKATGRYKKAERSLQMEQENNSALTTQNRRLQRDLE---- 336
I A +E+ RA+ A E+ KA + E +L+ ++E QN++L+ D+E
Sbjct: 1463 ISARYAEERDRAEAEAREKETKALSLARALEEALEAKEE----FERQNKQLRADMEDLMS 1518
Query: 337 ----------EVNETKEARDQEIKVLKTKVERLERRVRT---GGREIEAMLQSFNFSFE 474
E+ ++K A +Q+++ ++T++E LE ++ +E +Q+ FE
Sbjct: 1519 SKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFE 1577
Score = 32.7 bits (73), Expect = 0.73
Identities = 38/177 (21%), Positives = 69/177 (38%), Gaps = 35/177 (19%)
Frame = +1
Query: 19 ELEVETGKKYKATVSAQQIKIQSLDAQLDAKIEEINQAXXXXXXXXXXXXXIMALMVDEQ 198
E E+E +K +A A + K++ L+A+IE N+A + A M D Q
Sbjct: 1602 EAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRK---LQAQMKDYQ 1658
Query: 199 RRADNAIEQIEKATGRYKKAERSLQM----------------------EQENN------- 291
R + A ++ + K++E+ L+ EQE +
Sbjct: 1659 RELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEIA 1718
Query: 292 ------SALTTQNRRLQRDLEEVNETKEARDQEIKVLKTKVERLERRVRTGGREIEA 444
SAL + RRL+ + ++ E E +++L + + +V T E+ A
Sbjct: 1719 NSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNTELAA 1775
>sp|P35580|MYH10_HUMAN Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy
chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin
heavy chain, type B) (Nonmuscle myosin heavy chain-B)
(NMMHC-B)
Length = 1976
Score = 80.9 bits (198), Expect = 2e-15
Identities = 45/134 (33%), Positives = 70/134 (52%)
Frame = +1
Query: 1 LHEKIEELEVETGKKYKATVSAQQIKIQSLDAQLDAKIEEINQAXXXXXXXXXXXXXIMA 180
L K++ELE K+KAT+SA + KI L+ QL+ + +E A I
Sbjct: 1797 LKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFM 1856
Query: 181 LMVDEQRRADNAIEQIEKATGRYKKAERSLQMEQENNSALTTQNRRLQRDLEEVNETKEA 360
+ DE+R AD EQ+EKA R K+ +R L+ +E + R+LQR+L++ E E
Sbjct: 1857 QVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEG 1916
Query: 361 RDQEIKVLKTKVER 402
+E+ LK ++ R
Sbjct: 1917 LSREVSTLKNRLRR 1930
Score = 35.0 bits (79), Expect = 0.15
Identities = 29/119 (24%), Positives = 58/119 (48%), Gaps = 18/119 (15%)
Frame = +1
Query: 172 IMALMVDEQRRAD-NAIEQIEKATGRYKKAERSLQMEQENNSALTTQNRRLQRDLE---- 336
I A +E+ RA+ A E+ KA + E +L+ ++E QN++L+ D+E
Sbjct: 1463 ISARYAEERDRAEAEAREKETKALSLARALEEALEAKEE----FERQNKQLRADMEDLMS 1518
Query: 337 ----------EVNETKEARDQEIKVLKTKVERLERRVRT---GGREIEAMLQSFNFSFE 474
E+ ++K A +Q+++ ++T++E LE ++ +E +Q+ FE
Sbjct: 1519 SKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFE 1577
Score = 32.7 bits (73), Expect = 0.73
Identities = 38/177 (21%), Positives = 69/177 (38%), Gaps = 35/177 (19%)
Frame = +1
Query: 19 ELEVETGKKYKATVSAQQIKIQSLDAQLDAKIEEINQAXXXXXXXXXXXXXIMALMVDEQ 198
E E+E +K +A A + K++ L+A+IE N+A + A M D Q
Sbjct: 1602 EAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRK---LQAQMKDYQ 1658
Query: 199 RRADNAIEQIEKATGRYKKAERSLQM----------------------EQENN------- 291
R + A ++ + K++E+ L+ EQE +
Sbjct: 1659 RELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEIT 1718
Query: 292 ------SALTTQNRRLQRDLEEVNETKEARDQEIKVLKTKVERLERRVRTGGREIEA 444
SAL + RRL+ + ++ E E +++L + + +V T E+ A
Sbjct: 1719 NSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAA 1775
>sp|Q8VDD5|MYH9_MOUSE Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy
chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin
heavy chain, type A) (Nonmuscle myosin heavy chain-A)
(NMMHC-A)
Length = 1960
Score = 80.9 bits (198), Expect = 2e-15
Identities = 43/134 (32%), Positives = 73/134 (54%)
Frame = +1
Query: 1 LHEKIEELEVETGKKYKATVSAQQIKIQSLDAQLDAKIEEINQAXXXXXXXXXXXXXIMA 180
L K++E+E KYKA+++A + KI L+ QLD + +E A ++
Sbjct: 1790 LKAKLQEMESAVKSKYKASIAALEAKIAQLEEQLDNETKERQAASKQVRRTEKKLKDVLL 1849
Query: 181 LMVDEQRRADNAIEQIEKATGRYKKAERSLQMEQENNSALTTQNRRLQRDLEEVNETKEA 360
+ DE+R A+ +Q +KA+ R K+ +R L+ +E R+LQR+LE+ ET +A
Sbjct: 1850 QVEDERRNAEQFKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADA 1909
Query: 361 RDQEIKVLKTKVER 402
++E+ LK K+ R
Sbjct: 1910 MNREVSSLKNKLRR 1923
Score = 36.6 bits (83), Expect = 0.050
Identities = 35/159 (22%), Positives = 67/159 (42%), Gaps = 14/159 (8%)
Frame = +1
Query: 58 VSAQQIKIQSLDAQLDAKIEEINQAXXXXXXXXXXXXXIMALMVDEQRRADNAIEQIEKA 237
++ Q +I L QL K EE+ A +A + +E + + A+++I +
Sbjct: 1064 IAELQAQIAELKMQLAKKEEELQAA--------------LARVEEEAAQKNMALKKIREL 1109
Query: 238 TGRYKKAERSLQMEQENNSALTTQNRRLQRDLEEVN--------------ETKEARDQEI 375
+ + + L+ E+ + + Q R L +LE + E + R+QE+
Sbjct: 1110 ETQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEV 1169
Query: 376 KVLKTKVERLERRVRTGGREIEAMLQSFNFSFEIAASPL 492
+LK + LE +T +I+ M Q + + E A L
Sbjct: 1170 SILK---KTLEDEAKTHEAQIQEMRQKHSQAVEELADQL 1205
>sp|Q9JLT0|MYH10_RAT Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy
chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin
heavy chain, type B) (Nonmuscle myosin heavy chain-B)
(NMMHC-B)
Length = 1976
Score = 80.9 bits (198), Expect = 2e-15
Identities = 45/134 (33%), Positives = 70/134 (52%)
Frame = +1
Query: 1 LHEKIEELEVETGKKYKATVSAQQIKIQSLDAQLDAKIEEINQAXXXXXXXXXXXXXIMA 180
L K++ELE K+KAT+SA + KI L+ QL+ + +E A I
Sbjct: 1797 LKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFM 1856
Query: 181 LMVDEQRRADNAIEQIEKATGRYKKAERSLQMEQENNSALTTQNRRLQRDLEEVNETKEA 360
+ DE+R AD EQ+EKA R K+ +R L+ +E + R+LQR+L++ E E
Sbjct: 1857 QVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEG 1916
Query: 361 RDQEIKVLKTKVER 402
+E+ LK ++ R
Sbjct: 1917 LSREVSTLKNRLRR 1930
Score = 37.0 bits (84), Expect = 0.039
Identities = 39/179 (21%), Positives = 80/179 (44%), Gaps = 21/179 (11%)
Frame = +1
Query: 1 LHEKIEELEVETGKKYKATVSAQQIKIQSLDAQLDAK---IEEINQAXXXXXXXXXXXXX 171
L +++EE +V K + T + Q ++ L LD + + + +
Sbjct: 1404 LSQRLEE-KVLAYDKLEKTKNRLQQELDDLTVDLDHQRQIVSNLEKKQKKFDQLLAEEKG 1462
Query: 172 IMALMVDEQRRAD-NAIEQIEKATGRYKKAERSLQMEQENNSALTTQNRRLQRDLE---- 336
I A +E+ RA+ A E+ KA + E +L+ ++E QN++L+ D+E
Sbjct: 1463 ISARYAEERDRAEAEAREKETKALSLARALEEALEAKEE----FERQNKQLRADMEDLMS 1518
Query: 337 ----------EVNETKEARDQEIKVLKTKVERLERRVRT---GGREIEAMLQSFNFSFE 474
E+ ++K A +Q+++ ++T++E LE ++ +E +Q+ FE
Sbjct: 1519 SKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFE 1577
Score = 32.7 bits (73), Expect = 0.73
Identities = 38/177 (21%), Positives = 69/177 (38%), Gaps = 35/177 (19%)
Frame = +1
Query: 19 ELEVETGKKYKATVSAQQIKIQSLDAQLDAKIEEINQAXXXXXXXXXXXXXIMALMVDEQ 198
E E+E +K +A A + K++ L+A+IE N+A + A M D Q
Sbjct: 1602 EAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRK---LQAQMKDYQ 1658
Query: 199 RRADNAIEQIEKATGRYKKAERSLQM----------------------EQENN------- 291
R + A ++ + K++E+ L+ EQE +
Sbjct: 1659 RELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEIA 1718
Query: 292 ------SALTTQNRRLQRDLEEVNETKEARDQEIKVLKTKVERLERRVRTGGREIEA 444
SAL + RRL+ + ++ E E +++L + + +V T E+ A
Sbjct: 1719 NSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNTELAA 1775
>sp|Q62812|MYH9_RAT Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy
chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin
heavy chain, type A) (Nonmuscle myosin heavy chain-A)
(NMMHC-A)
Length = 1961
Score = 80.9 bits (198), Expect = 2e-15
Identities = 43/134 (32%), Positives = 73/134 (54%)
Frame = +1
Query: 1 LHEKIEELEVETGKKYKATVSAQQIKIQSLDAQLDAKIEEINQAXXXXXXXXXXXXXIMA 180
L K++E+E KYKA+++A + KI L+ QLD + +E A ++
Sbjct: 1791 LKAKLQEMESAVKSKYKASIAALEAKIAQLEEQLDNETKERQAASKQVRRAEKKLKDVLL 1850
Query: 181 LMVDEQRRADNAIEQIEKATGRYKKAERSLQMEQENNSALTTQNRRLQRDLEEVNETKEA 360
+ DE+R A+ +Q +KA+ R K+ +R L+ +E R+LQR+LE+ ET +A
Sbjct: 1851 QVEDERRNAEQFKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADA 1910
Query: 361 RDQEIKVLKTKVER 402
++E+ LK K+ R
Sbjct: 1911 MNREVSSLKNKLRR 1924
Score = 35.0 bits (79), Expect = 0.15
Identities = 35/159 (22%), Positives = 66/159 (41%), Gaps = 14/159 (8%)
Frame = +1
Query: 58 VSAQQIKIQSLDAQLDAKIEEINQAXXXXXXXXXXXXXIMALMVDEQRRADNAIEQIEKA 237
++ Q +I L QL K EE+ A +A + +E + + A+++I +
Sbjct: 1064 IAELQAQIAELKMQLAKKEEELQAA--------------LARVEEEAAQKNMALKKIREL 1109
Query: 238 TGRYKKAERSLQMEQENNSALTTQNRRLQRDLEEVN--------------ETKEARDQEI 375
+ + + L+ E+ + Q R L +LE + E + R+QE+
Sbjct: 1110 ETQISELQEDLESERACRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEV 1169
Query: 376 KVLKTKVERLERRVRTGGREIEAMLQSFNFSFEIAASPL 492
+LK + LE +T +I+ M Q + + E A L
Sbjct: 1170 SILK---KTLEDEAKTHEAQIQEMRQKHSQAVEELAEQL 1205
>sp|Q27991|MYH10_BOVIN Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy
chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin
heavy chain, type B) (Nonmuscle myosin heavy chain-B)
(NMMHC-B)
Length = 1976
Score = 80.9 bits (198), Expect = 2e-15
Identities = 45/134 (33%), Positives = 70/134 (52%)
Frame = +1
Query: 1 LHEKIEELEVETGKKYKATVSAQQIKIQSLDAQLDAKIEEINQAXXXXXXXXXXXXXIMA 180
L K++ELE K+KAT+SA + KI L+ QL+ + +E A I
Sbjct: 1797 LKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFM 1856
Query: 181 LMVDEQRRADNAIEQIEKATGRYKKAERSLQMEQENNSALTTQNRRLQRDLEEVNETKEA 360
+ DE+R AD EQ+EKA R K+ +R L+ +E + R+LQR+L++ E E
Sbjct: 1857 QVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEG 1916
Query: 361 RDQEIKVLKTKVER 402
+E+ LK ++ R
Sbjct: 1917 LSREVSTLKNRLRR 1930
Score = 35.8 bits (81), Expect = 0.086
Identities = 39/179 (21%), Positives = 77/179 (43%), Gaps = 21/179 (11%)
Frame = +1
Query: 1 LHEKIEELEVETGKKYKATVSAQQIKIQSLDAQLDAK---IEEINQAXXXXXXXXXXXXX 171
L +++EE + K K QQ ++ L LD + + + +
Sbjct: 1404 LSQRLEEKALAYDKLEKTKTRLQQ-ELDDLLVDLDHQRQIVSNLEKKQKKFDQLLAEEKN 1462
Query: 172 IMALMVDEQRRAD-NAIEQIEKATGRYKKAERSLQMEQENNSALTTQNRRLQRDLE---- 336
I A +E+ RA+ A E+ KA + E +L+ +E QN++L+ D+E
Sbjct: 1463 ISARYAEERDRAEAEAREKETKALSLARALEEALEAREEAER----QNKQLRADMEDLMS 1518
Query: 337 ----------EVNETKEARDQEIKVLKTKVERLERRVRT---GGREIEAMLQSFNFSFE 474
E+ ++K A +Q+++ ++T++E LE ++ +E +Q+ FE
Sbjct: 1519 SKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFE 1577
Score = 32.7 bits (73), Expect = 0.73
Identities = 38/177 (21%), Positives = 69/177 (38%), Gaps = 35/177 (19%)
Frame = +1
Query: 19 ELEVETGKKYKATVSAQQIKIQSLDAQLDAKIEEINQAXXXXXXXXXXXXXIMALMVDEQ 198
E E+E +K +A A + K++ L+A+IE N+A + A M D Q
Sbjct: 1602 EAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRK---LQAQMKDYQ 1658
Query: 199 RRADNAIEQIEKATGRYKKAERSLQM----------------------EQENN------- 291
R + A ++ + K++E+ L+ EQE +
Sbjct: 1659 RELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEIA 1718
Query: 292 ------SALTTQNRRLQRDLEEVNETKEARDQEIKVLKTKVERLERRVRTGGREIEA 444
SAL + RRL+ + ++ E E +++L + + +V T E+ A
Sbjct: 1719 NSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNTELAA 1775
>sp|Q99105|MYSU_RABIT Myosin heavy chain, embryonic smooth muscle isoform
Length = 501
Score = 80.9 bits (198), Expect = 2e-15
Identities = 45/134 (33%), Positives = 70/134 (52%)
Frame = +1
Query: 1 LHEKIEELEVETGKKYKATVSAQQIKIQSLDAQLDAKIEEINQAXXXXXXXXXXXXXIMA 180
L K++ELE K+KAT+SA + KI L+ QL+ + +E A I
Sbjct: 322 LKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFM 381
Query: 181 LMVDEQRRADNAIEQIEKATGRYKKAERSLQMEQENNSALTTQNRRLQRDLEEVNETKEA 360
+ DE+R AD EQ+EKA R K+ +R L+ +E + R+LQR+L++ E E
Sbjct: 382 QVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEG 441
Query: 361 RDQEIKVLKTKVER 402
+E+ LK ++ R
Sbjct: 442 LSREVSTLKNRLRR 455
Score = 33.1 bits (74), Expect = 0.56
Identities = 37/177 (20%), Positives = 68/177 (38%), Gaps = 35/177 (19%)
Frame = +1
Query: 19 ELEVETGKKYKATVSAQQIKIQSLDAQLDAKIEEINQAXXXXXXXXXXXXXIMALMVDEQ 198
E E+E +K +A A + K++ L+A+IE N+A + A M D Q
Sbjct: 127 EAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARERRVKQLRR---LQAQMKDYQ 183
Query: 199 RRADNA------------------------IEQIEKATGRYKKAERSLQMEQEN------ 288
R + A I Q+++ ++A R + E++
Sbjct: 184 RELEEARGSRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEIA 243
Query: 289 -----NSALTTQNRRLQRDLEEVNETKEARDQEIKVLKTKVERLERRVRTGGREIEA 444
SAL + RRL+ + ++ E E +++L + + +V T E+ A
Sbjct: 244 NSASGKSALLDEKRRLEARMRQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAA 300
Score = 30.8 bits (68), Expect = 2.8
Identities = 23/84 (27%), Positives = 44/84 (52%), Gaps = 3/84 (3%)
Frame = +1
Query: 214 AIEQIEKATGRYKKAERSLQMEQENNSALTTQNRRLQRDLEEVNETKEARDQEIKVLKTK 393
A E+ KA + E +L+ ++E QN++L+ D+E++ +K+ + + L+
Sbjct: 3 AREKETKALSLSRALEEALEAKEE----FERQNKQLRADMEDLMSSKDDVGKNVHELEKS 58
Query: 394 VERLERRV---RTGGREIEAMLQS 456
LE++V RT E+E LQ+
Sbjct: 59 KRALEQQVEEMRTQLEELEDELQA 82
>sp|P35749|MYH11_HUMAN Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC)
Length = 1972
Score = 80.5 bits (197), Expect = 3e-15
Identities = 45/151 (29%), Positives = 77/151 (50%), Gaps = 5/151 (3%)
Frame = +1
Query: 1 LHEKIEELEVETGKKYKATVSAQQIKIQSLDAQLDAKIEEINQAXXXXXXXXXXXXXIMA 180
L K+ E+E K+K+T++A + KI L+ Q++ + E A I+
Sbjct: 1797 LRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILL 1856
Query: 181 LMVDEQRRADNAIEQIEKATGRYKKAERSLQMEQENNSALTTQNRRLQRDLEEVNETKEA 360
+ DE++ A+ EQ EK R K+ +R L+ +E + + R+LQR+L+E E+ EA
Sbjct: 1857 QVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEA 1916
Query: 361 RDQEIKVLKTKVERLERRV-----RTGGREI 438
+E+ LK+K+ R R+GGR +
Sbjct: 1917 MGREVNALKSKLRRGNETSFVPSRRSGGRRV 1947
Score = 37.4 bits (85), Expect = 0.029
Identities = 36/163 (22%), Positives = 65/163 (39%), Gaps = 14/163 (8%)
Frame = +1
Query: 7 EKIEELEVETGKKYKATVSAQQIKIQSLDAQLDAKIEEINQAXXXXXXXXXXXXXIMALM 186
EK++ + ++ Q +I L QL K EE+ A +A +
Sbjct: 1054 EKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA--------------LARL 1099
Query: 187 VDEQRRADNAIEQIEKATGRYKKAERSLQMEQENNSALTTQNRRLQRDLEEVN------- 345
DE + +NA+++I + G + L E+ + Q R L +LE +
Sbjct: 1100 DDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1159
Query: 346 -------ETKEARDQEIKVLKTKVERLERRVRTGGREIEAMLQ 453
E + R+QE+ VLK + L+ R+ +++ M Q
Sbjct: 1160 DSTATQQELRAKREQEVTVLK---KALDEETRSHEAQVQEMRQ 1199
Score = 35.0 bits (79), Expect = 0.15
Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 8/97 (8%)
Frame = +1
Query: 190 DEQRRADNAIEQIEKATGRYKKAERSLQME----QENNSA---LTTQNRRLQRDLEEV-N 345
+EQ + +++ KAT + ++ L E Q+N SA L QN+ L+ L E+
Sbjct: 1747 EEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEG 1806
Query: 346 ETKEARDQEIKVLKTKVERLERRVRTGGREIEAMLQS 456
K I L+ K+ +LE +V RE +A +S
Sbjct: 1807 AVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS 1843
Score = 33.5 bits (75), Expect = 0.43
Identities = 31/149 (20%), Positives = 60/149 (40%), Gaps = 2/149 (1%)
Frame = +1
Query: 1 LHEKIEELEVETGKKYKATVSAQQIK--IQSLDAQLDAKIEEINQAXXXXXXXXXXXXXI 174
LHE ELE E ++ A + ++++ ++ L+ Q D+ I+ +A
Sbjct: 1598 LHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDF 1657
Query: 175 MALMVDEQRRADNAIEQIEKATGRYKKAERSLQMEQENNSALTTQNRRLQRDLEEVNETK 354
+ D + D ++ + K E L QE+ +A ++ + EE+ E
Sbjct: 1658 QRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL 1717
Query: 355 EARDQEIKVLKTKVERLERRVRTGGREIE 441
+ L+ + RLE R+ E+E
Sbjct: 1718 ASSLSGRNALQDEKRRLEARIAQLEEELE 1746
>sp|P35579|MYH9_HUMAN Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy
chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin
heavy chain, type A) (Nonmuscle myosin heavy chain-A)
(NMMHC-A)
Length = 1960
Score = 79.7 bits (195), Expect = 5e-15
Identities = 43/134 (32%), Positives = 73/134 (54%)
Frame = +1
Query: 1 LHEKIEELEVETGKKYKATVSAQQIKIQSLDAQLDAKIEEINQAXXXXXXXXXXXXXIMA 180
L K++E+E KYKA+++A + KI L+ QLD + +E A ++
Sbjct: 1790 LKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLL 1849
Query: 181 LMVDEQRRADNAIEQIEKATGRYKKAERSLQMEQENNSALTTQNRRLQRDLEEVNETKEA 360
+ DE+R A+ +Q +KA+ R K+ +R L+ +E R+LQR+LE+ ET +A
Sbjct: 1850 QVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADA 1909
Query: 361 RDQEIKVLKTKVER 402
++E+ LK K+ R
Sbjct: 1910 MNREVSSLKNKLRR 1923
Score = 38.1 bits (87), Expect = 0.017
Identities = 35/159 (22%), Positives = 67/159 (42%), Gaps = 14/159 (8%)
Frame = +1
Query: 58 VSAQQIKIQSLDAQLDAKIEEINQAXXXXXXXXXXXXXIMALMVDEQRRADNAIEQIEKA 237
++ Q +I L QL K EE+ A +A + +E + + A+++I +
Sbjct: 1064 IAELQAQIAELKMQLAKKEEELQAA--------------LARVEEEAAQKNMALKKIREL 1109
Query: 238 TGRYKKAERSLQMEQENNSALTTQNRRLQRDLEEVN--------------ETKEARDQEI 375
+ + + L+ E+ + + Q R L +LE + E + R+QE+
Sbjct: 1110 ESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEV 1169
Query: 376 KVLKTKVERLERRVRTGGREIEAMLQSFNFSFEIAASPL 492
+LK + LE +T +I+ M Q + + E A L
Sbjct: 1170 NILK---KTLEEEAKTHEAQIQEMRQKHSQAVEELAEQL 1205
>sp|P10587|MYH11_CHICK Myosin-11 (Myosin heavy chain, gizzard smooth muscle)
Length = 1979
Score = 79.7 bits (195), Expect = 5e-15
Identities = 45/152 (29%), Positives = 80/152 (52%), Gaps = 6/152 (3%)
Frame = +1
Query: 1 LHEKIEELEVETGKKYKATVSAQQIKIQSLDAQLDAKIEEINQAXXXXXXXXXXXXXIMA 180
L K++E+E K+K+T++A + KI SL+ QL+ + E A +
Sbjct: 1803 LRSKLQEMEGAVKSKFKSTIAALEAKIASLEEQLEQEAREKQAAAKTLRQKDKKLKDALL 1862
Query: 181 LMVDEQRRADNAIEQIEKATGRYKKAERSLQMEQENNSALTTQNRRLQRDLEEVNETKEA 360
+ DE+++A+ +Q EK R K+ +R L+ +E + + R+LQR+L+E E+ +A
Sbjct: 1863 QVEDERKQAEQYKDQAEKGNLRLKQLKRQLEEAEEESQRINANRRKLQRELDEATESNDA 1922
Query: 361 RDQEIKVLKTKVERLERRV------RTGGREI 438
+E+ LK+K+ R V R+GGR +
Sbjct: 1923 LGREVAALKSKLRRGNEPVSFAPPRRSGGRRV 1954
Score = 33.1 bits (74), Expect = 0.56
Identities = 35/149 (23%), Positives = 72/149 (48%), Gaps = 10/149 (6%)
Frame = +1
Query: 1 LHEKIEELEVETGKKYKATVSAQQIKIQSLDAQLDAKIEEINQAXXXXXXXXXXXXXIMA 180
LHE+I EL+ + + KA ++ ++ ++Q+ A+L+ + + N A +
Sbjct: 1073 LHEQIAELQAQIAE-LKAQLAKKEEELQAALARLEDETSQKNNALKKIRELESHISDLQE 1131
Query: 181 LMVDEQRRADNAIEQIEKATGRYKKAERSLQMEQENNSALTTQNRR---------LQRDL 333
+ + ++ A N E+ ++ +A ++ ++E ++ T Q R L+R L
Sbjct: 1132 DL-ESEKAARNKAEKQKRDLSEELEALKT-ELEDTLDTTATQQELRAKREQEVTVLKRAL 1189
Query: 334 EEVNETKEARDQEIKVLKTK-VERLERRV 417
EE T EA+ QE++ T+ VE L ++
Sbjct: 1190 EEETRTHEAQVQEMRQKHTQAVEELTEQL 1218
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,336,499
Number of Sequences: 369166
Number of extensions: 915141
Number of successful extensions: 4597
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3975
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4537
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4650991475
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)