Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_021_B07
(788 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q61171|PRDX2_MOUSE Peroxiredoxin 2 (Thioredoxin peroxida... 278 2e-74
sp|Q90384|TDX_CYNPY Peroxiredoxin (Thioredoxin peroxidase) ... 277 2e-74
sp|Q9BGI3|PRDX2_BOVIN Peroxiredoxin 2 277 3e-74
sp|P35704|PRDX2_RAT Peroxiredoxin 2 (Thioredoxin peroxidase... 275 8e-74
sp|Q06830|PRDX1_HUMAN Peroxiredoxin 1 (Thioredoxin peroxida... 272 9e-73
sp|Q5E947|PRDX1_BOVIN Peroxiredoxin 1 271 1e-72
sp|P32119|PRDX2_HUMAN Peroxiredoxin 2 (Thioredoxin peroxida... 269 6e-72
sp|Q63716|PRDX1_RAT Peroxiredoxin 1 (Thioredoxin peroxidase... 268 1e-71
sp|Q9NL98|PRDX_ASCSU Peroxiredoxin (AsPrx) (Thioredoxin per... 265 8e-71
sp|P35700|PRDX1_MOUSE Peroxiredoxin 1 (Thioredoxin peroxida... 264 2e-70
>sp|Q61171|PRDX2_MOUSE Peroxiredoxin 2 (Thioredoxin peroxidase 1) (Thioredoxin-dependent
peroxide reductase 1) (Thiol-specific antioxidant
protein) (TSA)
Length = 198
Score = 278 bits (710), Expect = 2e-74
Identities = 129/188 (68%), Positives = 152/188 (80%)
Frame = +2
Query: 146 QPGHVAPPFTAKAVKSGEIIDLSLSDYIGKYVVLFFYPADFTFVCPTEIIAFSDRVNEFH 325
Q G AP FTA AV G ++ LSDY GKYVVLFFYP DFTFVCPTEIIAFSD +F
Sbjct: 7 QIGKSAPDFTATAVVDGAFKEIKLSDYRGKYVVLFFYPLDFTFVCPTEIIAFSDHAEDFR 66
Query: 326 EINCEVLACSTDSEFSHFAWTGTPRKKGGVGQLEIPLIADKTKSISKNYGVLKEDEGLAF 505
++ CEVL S DS+F+H AW TPRK+GG+G L IPL+AD TKS+S+NYGVLK DEG+A+
Sbjct: 67 KLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTKSLSQNYGVLKNDEGIAY 126
Query: 506 RGLFIISDKGLIRQMTINDMPVGRSIDETLRLVQAFQHTDIHGEVCPAGWKPGSKTIKPT 685
RGLFII KG++RQ+T+ND+PVGRS+DE LRLVQAFQ+TD HGEVCPAGWKPGS TIKP
Sbjct: 127 RGLFIIDAKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPGSDTIKPN 186
Query: 686 IQDAGEYF 709
+ D+ EYF
Sbjct: 187 VDDSKEYF 194
>sp|Q90384|TDX_CYNPY Peroxiredoxin (Thioredoxin peroxidase) (Thioredoxin-dependent
peroxide reductase) (Animal blastomere protein, 25 kDa)
(ABP-25)
Length = 200
Score = 277 bits (709), Expect = 2e-74
Identities = 132/189 (69%), Positives = 154/189 (81%), Gaps = 1/189 (0%)
Frame = +2
Query: 146 QPGHVAPPFTAKAVK-SGEIIDLSLSDYIGKYVVLFFYPADFTFVCPTEIIAFSDRVNEF 322
Q G AP F AKAV GE D+ L+DY GKYVV FFYP DFTFVCPTEIIAFSDR EF
Sbjct: 7 QIGKPAPEFQAKAVMPGGEFKDIKLADYRGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEF 66
Query: 323 HEINCEVLACSTDSEFSHFAWTGTPRKKGGVGQLEIPLIADKTKSISKNYGVLKEDEGLA 502
+INCE++A S DS F H AWT T RK+GG+G ++IPL+AD ++IS++YGVLKEDEG++
Sbjct: 67 RKINCELIAASVDSHFCHLAWTNTSRKEGGLGSMKIPLVADTKRTISQDYGVLKEDEGIS 126
Query: 503 FRGLFIISDKGLIRQMTINDMPVGRSIDETLRLVQAFQHTDIHGEVCPAGWKPGSKTIKP 682
FRGLFII DKG++RQ+TIND+PVGRS+DETLRLVQAFQHTD GEVCPAGWKPGS TIKP
Sbjct: 127 FRGLFIIDDKGILRQITINDLPVGRSVDETLRLVQAFQHTDKFGEVCPAGWKPGSDTIKP 186
Query: 683 TIQDAGEYF 709
I + EYF
Sbjct: 187 DISKSKEYF 195
>sp|Q9BGI3|PRDX2_BOVIN Peroxiredoxin 2
Length = 199
Score = 277 bits (708), Expect = 3e-74
Identities = 128/193 (66%), Positives = 152/193 (78%)
Frame = +2
Query: 131 CKMLLQPGHVAPPFTAKAVKSGEIIDLSLSDYIGKYVVLFFYPADFTFVCPTEIIAFSDR 310
C G AP F A AV G ++ LSDY GKYVVLFFYP DFTFVCPTEI+AFSDR
Sbjct: 3 CVCKAHVGKPAPEFQATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIVAFSDR 62
Query: 311 VNEFHEINCEVLACSTDSEFSHFAWTGTPRKKGGVGQLEIPLIADKTKSISKNYGVLKED 490
EFH++NCEVL S DS+F+H AW TPRK+GG+G L IPL+AD T+ +S +YGVLKED
Sbjct: 63 AAEFHKLNCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRKLSSDYGVLKED 122
Query: 491 EGLAFRGLFIISDKGLIRQMTINDMPVGRSIDETLRLVQAFQHTDIHGEVCPAGWKPGSK 670
EG+A+RGLF+I KG++RQ+TIND+PVGRS+DE LRLVQAFQ+TD HGEVCPAGW PGS
Sbjct: 123 EGIAYRGLFVIDGKGVLRQVTINDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWTPGSD 182
Query: 671 TIKPTIQDAGEYF 709
TIKP + D+ EYF
Sbjct: 183 TIKPNVDDSKEYF 195
>sp|P35704|PRDX2_RAT Peroxiredoxin 2 (Thioredoxin peroxidase 1) (Thioredoxin-dependent
peroxide reductase 1) (Thiol-specific antioxidant
protein) (TSA)
Length = 198
Score = 275 bits (704), Expect = 8e-74
Identities = 127/186 (68%), Positives = 150/186 (80%)
Frame = +2
Query: 152 GHVAPPFTAKAVKSGEIIDLSLSDYIGKYVVLFFYPADFTFVCPTEIIAFSDRVNEFHEI 331
G AP FT AV G ++ LSDY GKYVVLFFYP DFTFVCPTEIIAFSD +F ++
Sbjct: 9 GKPAPDFTGTAVVDGAFKEIKLSDYRGKYVVLFFYPLDFTFVCPTEIIAFSDHAEDFRKL 68
Query: 332 NCEVLACSTDSEFSHFAWTGTPRKKGGVGQLEIPLIADKTKSISKNYGVLKEDEGLAFRG 511
CEVL S DS+F+H AW TPRK+GG+G L IPL+AD TKS+S+NYGVLK DEG+A+RG
Sbjct: 69 GCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTKSLSQNYGVLKNDEGIAYRG 128
Query: 512 LFIISDKGLIRQMTINDMPVGRSIDETLRLVQAFQHTDIHGEVCPAGWKPGSKTIKPTIQ 691
LFII KG++RQ+T+ND+PVGRS+DE LRLVQAFQ+TD HGEVCPAGWKPGS TIKP +
Sbjct: 129 LFIIDAKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPGSDTIKPNVD 188
Query: 692 DAGEYF 709
D+ EYF
Sbjct: 189 DSKEYF 194
>sp|Q06830|PRDX1_HUMAN Peroxiredoxin 1 (Thioredoxin peroxidase 2) (Thioredoxin-dependent
peroxide reductase 2) (Proliferation-associated protein
PAG) (Natural killer cell-enhancing factor A) (NKEF-A)
Length = 199
Score = 272 bits (695), Expect = 9e-73
Identities = 125/187 (66%), Positives = 152/187 (81%), Gaps = 1/187 (0%)
Frame = +2
Query: 152 GHVAPPFTAKAVK-SGEIIDLSLSDYIGKYVVLFFYPADFTFVCPTEIIAFSDRVNEFHE 328
GH AP F A AV G+ D+SLSDY GKYVV FFYP DFTFVCPTEIIAFSDR EF +
Sbjct: 9 GHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKK 68
Query: 329 INCEVLACSTDSEFSHFAWTGTPRKKGGVGQLEIPLIADKTKSISKNYGVLKEDEGLAFR 508
+NC+V+ S DS F H AW TP+K+GG+G + IPL++D ++I+++YGVLK DEG++FR
Sbjct: 69 LNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGISFR 128
Query: 509 GLFIISDKGLIRQMTINDMPVGRSIDETLRLVQAFQHTDIHGEVCPAGWKPGSKTIKPTI 688
GLFII DKG++RQ+T+ND+PVGRS+DETLRLVQAFQ TD HGEVCPAGWKPGS TIKP +
Sbjct: 129 GLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDV 188
Query: 689 QDAGEYF 709
Q + EYF
Sbjct: 189 QKSKEYF 195
>sp|Q5E947|PRDX1_BOVIN Peroxiredoxin 1
Length = 199
Score = 271 bits (693), Expect = 1e-72
Identities = 126/187 (67%), Positives = 152/187 (81%), Gaps = 1/187 (0%)
Frame = +2
Query: 152 GHVAPPFTAKAVK-SGEIIDLSLSDYIGKYVVLFFYPADFTFVCPTEIIAFSDRVNEFHE 328
GH AP F A AV G+ D+SL+DY GKYVV FFYP DFTFVCPTEIIAFSDR EF +
Sbjct: 9 GHRAPQFKATAVMPDGQFKDISLADYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKK 68
Query: 329 INCEVLACSTDSEFSHFAWTGTPRKKGGVGQLEIPLIADKTKSISKNYGVLKEDEGLAFR 508
+NC+V+ S DS F H AW TP+K+GG+G + IPLI+D ++I+++YGVLK DEG++FR
Sbjct: 69 LNCQVIGASVDSHFCHLAWINTPKKQGGLGPMNIPLISDPKRTIAQDYGVLKADEGISFR 128
Query: 509 GLFIISDKGLIRQMTINDMPVGRSIDETLRLVQAFQHTDIHGEVCPAGWKPGSKTIKPTI 688
GLFII DKG++RQ+TIND+PVGRS+DETLRLVQAFQ TD HGEVCPAGWKPGS TIKP +
Sbjct: 129 GLFIIDDKGILRQITINDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDV 188
Query: 689 QDAGEYF 709
Q + EYF
Sbjct: 189 QKSKEYF 195
>sp|P32119|PRDX2_HUMAN Peroxiredoxin 2 (Thioredoxin peroxidase 1) (Thioredoxin-dependent
peroxide reductase 1) (Thiol-specific antioxidant
protein) (TSA) (PRP) (Natural killer cell-enhancing
factor B) (NKEF-B)
Length = 198
Score = 269 bits (688), Expect = 6e-72
Identities = 124/186 (66%), Positives = 150/186 (80%)
Frame = +2
Query: 152 GHVAPPFTAKAVKSGEIIDLSLSDYIGKYVVLFFYPADFTFVCPTEIIAFSDRVNEFHEI 331
G AP F A AV G ++ LSDY GKYVVLFFYP DFTFVCPTEIIAFS+R +F ++
Sbjct: 9 GKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSNRAEDFRKL 68
Query: 332 NCEVLACSTDSEFSHFAWTGTPRKKGGVGQLEIPLIADKTKSISKNYGVLKEDEGLAFRG 511
CEVL S DS+F+H AW TPRK+GG+G L IPL+AD T+ +S++YGVLK DEG+A+RG
Sbjct: 69 GCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLKTDEGIAYRG 128
Query: 512 LFIISDKGLIRQMTINDMPVGRSIDETLRLVQAFQHTDIHGEVCPAGWKPGSKTIKPTIQ 691
LFII KG++RQ+T+ND+PVGRS+DE LRLVQAFQ+TD HGEVCPAGWKPGS TIKP +
Sbjct: 129 LFIIDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPGSDTIKPNVD 188
Query: 692 DAGEYF 709
D+ EYF
Sbjct: 189 DSKEYF 194
>sp|Q63716|PRDX1_RAT Peroxiredoxin 1 (Thioredoxin peroxidase 2) (Thioredoxin-dependent
peroxide reductase 2) (Heme-binding 23 kDa protein)
(HBP23)
Length = 199
Score = 268 bits (685), Expect = 1e-71
Identities = 124/187 (66%), Positives = 150/187 (80%), Gaps = 1/187 (0%)
Frame = +2
Query: 152 GHVAPPFTAKAVK-SGEIIDLSLSDYIGKYVVLFFYPADFTFVCPTEIIAFSDRVNEFHE 328
GH AP F A AV G+ D+SLSDY GKYVV FFYP DFTFVCPTEIIAFSDR EF +
Sbjct: 9 GHPAPSFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKK 68
Query: 329 INCEVLACSTDSEFSHFAWTGTPRKKGGVGQLEIPLIADKTKSISKNYGVLKEDEGLAFR 508
+NC+V+ S DS F H AW TP+K+GG+G + IPL++D ++I+++YGVLK DEG++FR
Sbjct: 69 LNCQVIGASVDSHFCHLAWINTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGISFR 128
Query: 509 GLFIISDKGLIRQMTINDMPVGRSIDETLRLVQAFQHTDIHGEVCPAGWKPGSKTIKPTI 688
GLFII DKG++RQ+TIND+PVGRS+DE LRLVQAFQ TD HGEVCPAGWKPGS TIKP +
Sbjct: 129 GLFIIDDKGILRQITINDLPVGRSVDEILRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDV 188
Query: 689 QDAGEYF 709
+ EYF
Sbjct: 189 NKSKEYF 195
>sp|Q9NL98|PRDX_ASCSU Peroxiredoxin (AsPrx) (Thioredoxin peroxidase)
Length = 195
Score = 265 bits (678), Expect = 8e-71
Identities = 122/187 (65%), Positives = 152/187 (81%)
Frame = +2
Query: 152 GHVAPPFTAKAVKSGEIIDLSLSDYIGKYVVLFFYPADFTFVCPTEIIAFSDRVNEFHEI 331
G AP FTA AV G+ +SLSDY GKYVVLFFYP DFTFVCPTEIIAFS+ V EF ++
Sbjct: 7 GKPAPEFTATAVVDGDFKSISLSDYKGKYVVLFFYPMDFTFVCPTEIIAFSEHVGEFKKL 66
Query: 332 NCEVLACSTDSEFSHFAWTGTPRKKGGVGQLEIPLIADKTKSISKNYGVLKEDEGLAFRG 511
EVLA STDS+FSH AW TPRK+GG+G+++IP+I+D IS++YGVLKED+G+A+RG
Sbjct: 67 GVEVLAASTDSQFSHLAWINTPRKQGGLGEMKIPIISDNNHQISRDYGVLKEDDGIAYRG 126
Query: 512 LFIISDKGLIRQMTINDMPVGRSIDETLRLVQAFQHTDIHGEVCPAGWKPGSKTIKPTIQ 691
LFII KG++RQ+T+ND+PVGRS+ ETLRLVQAFQ D HGEVCPAGW PG+ TIKP ++
Sbjct: 127 LFIIDPKGILRQITVNDLPVGRSVTETLRLVQAFQFVDKHGEVCPAGWTPGADTIKPGVK 186
Query: 692 DAGEYFQ 712
++ YF+
Sbjct: 187 ESKAYFE 193
>sp|P35700|PRDX1_MOUSE Peroxiredoxin 1 (Thioredoxin peroxidase 2) (Thioredoxin-dependent
peroxide reductase 2) (Osteoblast-specific factor 3)
(OSF-3) (Macrophage 23 kDa stress protein)
Length = 199
Score = 264 bits (674), Expect = 2e-70
Identities = 122/187 (65%), Positives = 151/187 (80%), Gaps = 1/187 (0%)
Frame = +2
Query: 152 GHVAPPFTAKAVK-SGEIIDLSLSDYIGKYVVLFFYPADFTFVCPTEIIAFSDRVNEFHE 328
G+ AP F A AV G+ D+SLS+Y GKYVV FFYP DFTFVCPTEIIAFSDR +EF +
Sbjct: 9 GYPAPNFKATAVMPDGQFKDISLSEYKGKYVVFFFYPLDFTFVCPTEIIAFSDRADEFKK 68
Query: 329 INCEVLACSTDSEFSHFAWTGTPRKKGGVGQLEIPLIADKTKSISKNYGVLKEDEGLAFR 508
+NC+V+ S DS F H AW TP+K+GG+G + IPLI+D ++I+++YGVLK DEG++FR
Sbjct: 69 LNCQVIGASVDSHFCHLAWINTPKKQGGLGPMNIPLISDPKRTIAQDYGVLKADEGISFR 128
Query: 509 GLFIISDKGLIRQMTINDMPVGRSIDETLRLVQAFQHTDIHGEVCPAGWKPGSKTIKPTI 688
GLFII DKG++RQ+TIND+PVGRS+DE +RLVQAFQ TD HGEVCPAGWKPGS TIKP +
Sbjct: 129 GLFIIDDKGILRQITINDLPVGRSVDEIIRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDV 188
Query: 689 QDAGEYF 709
+ EYF
Sbjct: 189 NKSKEYF 195
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,569,882
Number of Sequences: 369166
Number of extensions: 2091286
Number of successful extensions: 5843
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5626
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5762
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7454154400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)