Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_021_B04
(668 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P51893|SAHHA_XENLA Adenosylhomocysteinase A (S-adenosyl-... 275 8e-74
sp|O93477|SAHHB_XENLA Adenosylhomocysteinase B (S-adenosyl-... 274 2e-73
sp|P50247|SAHH_MOUSE Adenosylhomocysteinase (S-adenosyl-L-h... 269 6e-72
sp|P10760|SAHH_RAT Adenosylhomocysteinase (S-adenosyl-L-hom... 267 2e-71
sp|P23526|SAHH_HUMAN Adenosylhomocysteinase (S-adenosyl-L-h... 265 1e-70
sp|Q710C4|SAHH_PIG Adenosylhomocysteinase (S-adenosyl-L-hom... 264 2e-70
sp|P27604|SAHH_CAEEL Adenosylhomocysteinase (S-adenosyl-L-h... 261 9e-70
sp|Q27580|SAHH_DROME Adenosylhomocysteinase (S-adenosyl-L-h... 260 3e-69
sp|O76757|SAHH_ANOGA Adenosylhomocysteinase (S-adenosyl-L-h... 248 1e-65
sp|O13639|SAHH_SCHPO Adenosylhomocysteinase (S-adenosyl-L-h... 247 2e-65
>sp|P51893|SAHHA_XENLA Adenosylhomocysteinase A (S-adenosyl-L-homocysteine hydrolase A)
(AdoHcyase A)
Length = 433
Score = 275 bits (703), Expect = 8e-74
Identities = 132/162 (81%), Positives = 139/162 (85%)
Frame = +3
Query: 3 IFVTATGCKDIIVGRHFEQMLDDSIVCNIGHFDIEVEAKWLYENCKSKDTIKPQVDRYTL 182
IFVT TGC DI+ GRHFE M DDSIVCNIGHFDIE++ KWL EN K IKPQVDRY L
Sbjct: 272 IFVTTTGCADIVEGRHFENMKDDSIVCNIGHFDIELDVKWLNENAVKKVNIKPQVDRYLL 331
Query: 183 KNGRHIILLAEGRLVNLGCAHGHPSFVMSNSFTNQVLAQIELWTKTDQYKVGVYFLPKKL 362
KNGRHIILLAEGRLVNLGCA GHPSFVMSNSFTNQV+AQIELWT TD+Y VGVYFLPKKL
Sbjct: 332 KNGRHIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTNTDKYPVGVYFLPKKL 391
Query: 363 DEEVAQAHLEHLGVKLTKLTDSQADYLGIPIEGPFKPDHYRY 488
DE VA AHL+ LGVKLTKLTD QA YLG+ EGPFKPDHYRY
Sbjct: 392 DEAVAAAHLDKLGVKLTKLTDKQAKYLGLDKEGPFKPDHYRY 433
>sp|O93477|SAHHB_XENLA Adenosylhomocysteinase B (S-adenosyl-L-homocysteine hydrolase B)
(AdoHcyase B)
Length = 433
Score = 274 bits (700), Expect = 2e-73
Identities = 130/162 (80%), Positives = 139/162 (85%)
Frame = +3
Query: 3 IFVTATGCKDIIVGRHFEQMLDDSIVCNIGHFDIEVEAKWLYENCKSKDTIKPQVDRYTL 182
IFVT TGC DI+ GRHFE M DDSIVCNIGHFD+E++ KWL +N K IKPQVDRY L
Sbjct: 272 IFVTTTGCADIVEGRHFENMKDDSIVCNIGHFDVELDVKWLNDNAAKKINIKPQVDRYLL 331
Query: 183 KNGRHIILLAEGRLVNLGCAHGHPSFVMSNSFTNQVLAQIELWTKTDQYKVGVYFLPKKL 362
KNGRHIILLAEGRLVNLGCA GHPSFVMSNSFTNQV+AQIELWT TD+Y VGVYFLPKKL
Sbjct: 332 KNGRHIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTNTDKYPVGVYFLPKKL 391
Query: 363 DEEVAQAHLEHLGVKLTKLTDSQADYLGIPIEGPFKPDHYRY 488
DE VA AHL+ LGVKLTKLTD QA YLG+ EGPFKPDHYRY
Sbjct: 392 DEAVAAAHLDKLGVKLTKLTDKQAKYLGLDKEGPFKPDHYRY 433
>sp|P50247|SAHH_MOUSE Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase)
(AdoHcyase) (Liver copper binding protein) (CUBP)
Length = 432
Score = 269 bits (687), Expect = 6e-72
Identities = 128/162 (79%), Positives = 139/162 (85%)
Frame = +3
Query: 3 IFVTATGCKDIIVGRHFEQMLDDSIVCNIGHFDIEVEAKWLYENCKSKDTIKPQVDRYTL 182
IFVT TGC DII+GRHFEQM DD+IVCNIGHFD+E++ KWL EN K IKPQVDRY L
Sbjct: 271 IFVTTTGCVDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYWL 330
Query: 183 KNGRHIILLAEGRLVNLGCAHGHPSFVMSNSFTNQVLAQIELWTKTDQYKVGVYFLPKKL 362
KNGR IILLAEGRLVNLGCA GHPSFVMSNSFTNQV+AQIELWT D+Y VGV+FLPKKL
Sbjct: 331 KNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKL 390
Query: 363 DEEVAQAHLEHLGVKLTKLTDSQADYLGIPIEGPFKPDHYRY 488
DE VA+AHL L VKLTKLT+ QA YLG+PI GPFKPDHYRY
Sbjct: 391 DEAVAEAHLGKLNVKLTKLTEKQAQYLGMPINGPFKPDHYRY 432
>sp|P10760|SAHH_RAT Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase)
(AdoHcyase)
Length = 432
Score = 267 bits (683), Expect = 2e-71
Identities = 127/162 (78%), Positives = 138/162 (85%)
Frame = +3
Query: 3 IFVTATGCKDIIVGRHFEQMLDDSIVCNIGHFDIEVEAKWLYENCKSKDTIKPQVDRYTL 182
IFVT TGC DII+GRHFEQM DD+IVCNIGHFD+E++ KWL EN K IKPQVDRY L
Sbjct: 271 IFVTTTGCVDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYLL 330
Query: 183 KNGRHIILLAEGRLVNLGCAHGHPSFVMSNSFTNQVLAQIELWTKTDQYKVGVYFLPKKL 362
KNG IILLAEGRLVNLGCA GHPSFVMSNSFTNQV+AQIELWT D+Y VGV+FLPKKL
Sbjct: 331 KNGHRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKL 390
Query: 363 DEEVAQAHLEHLGVKLTKLTDSQADYLGIPIEGPFKPDHYRY 488
DE VA+AHL L VKLTKLT+ QA YLG+PI GPFKPDHYRY
Sbjct: 391 DEAVAEAHLGKLNVKLTKLTEKQAQYLGMPINGPFKPDHYRY 432
>sp|P23526|SAHH_HUMAN Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase)
(AdoHcyase)
Length = 432
Score = 265 bits (676), Expect = 1e-70
Identities = 126/162 (77%), Positives = 138/162 (85%)
Frame = +3
Query: 3 IFVTATGCKDIIVGRHFEQMLDDSIVCNIGHFDIEVEAKWLYENCKSKDTIKPQVDRYTL 182
IFVT TGC DII+GRHFEQM DD+IVCNIGHFD+E++ KWL EN K IKPQVDRY L
Sbjct: 271 IFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRL 330
Query: 183 KNGRHIILLAEGRLVNLGCAHGHPSFVMSNSFTNQVLAQIELWTKTDQYKVGVYFLPKKL 362
KNGR IILLAEGRLVNLGCA GHPSFVMSNSFTNQV+AQIELWT D+Y VGV+FLPKKL
Sbjct: 331 KNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKL 390
Query: 363 DEEVAQAHLEHLGVKLTKLTDSQADYLGIPIEGPFKPDHYRY 488
DE VA+AHL L VKLTKLT+ QA YLG+ +GPFKPDHYRY
Sbjct: 391 DEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY 432
>sp|Q710C4|SAHH_PIG Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase)
(AdoHcyase)
Length = 432
Score = 264 bits (674), Expect = 2e-70
Identities = 127/162 (78%), Positives = 137/162 (84%)
Frame = +3
Query: 3 IFVTATGCKDIIVGRHFEQMLDDSIVCNIGHFDIEVEAKWLYENCKSKDTIKPQVDRYTL 182
IFVT TGC DII+GRHFEQM DD+IVCNIGHFD+E++ KWL EN K IKPQVDRY L
Sbjct: 271 IFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYLL 330
Query: 183 KNGRHIILLAEGRLVNLGCAHGHPSFVMSNSFTNQVLAQIELWTKTDQYKVGVYFLPKKL 362
KNG IILLAEGRLVNLGCA GHPSFVMSNSFTNQVLAQIELWT D+Y VGV+FLPKKL
Sbjct: 331 KNGHRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVLAQIELWTHPDKYPVGVHFLPKKL 390
Query: 363 DEEVAQAHLEHLGVKLTKLTDSQADYLGIPIEGPFKPDHYRY 488
DE VA+AHL L VKLTKLT+ QA YLG+ EGPFKPDHYRY
Sbjct: 391 DEAVAEAHLGKLNVKLTKLTEKQAQYLGMSREGPFKPDHYRY 432
>sp|P27604|SAHH_CAEEL Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase)
(AdoHcyase) (Dumpy-14 protein)
Length = 437
Score = 261 bits (668), Expect = 9e-70
Identities = 121/165 (73%), Positives = 138/165 (83%), Gaps = 3/165 (1%)
Frame = +3
Query: 3 IFVTATGCKDIIVGRHFEQMLDDSIVCNIGHFDIEVEAKWLYENCKSKDTIKPQVDRYTL 182
I VT TGCKDI+ G+HFE + +D+IVCN+GHFD E++ KWL N KDTIKPQVDRYTL
Sbjct: 273 IIVTTTGCKDIVTGKHFELLPNDAIVCNVGHFDCEIDVKWLNTNATKKDTIKPQVDRYTL 332
Query: 183 KNGRHIILLAEGRLVNLGCAHGHPSFVMSNSFTNQVLAQIELWTK---TDQYKVGVYFLP 353
KNGRH+ILLAEGRLVNLGCA GHPSFVMSNSFTNQVLAQ+ELWTK +YK+G+Y LP
Sbjct: 333 KNGRHVILLAEGRLVNLGCATGHPSFVMSNSFTNQVLAQVELWTKFGTPQEYKLGLYVLP 392
Query: 354 KKLDEEVAQAHLEHLGVKLTKLTDSQADYLGIPIEGPFKPDHYRY 488
K LDEEVA HL LGVKLTKL+D QA YLG+P+ GP+KPDHYRY
Sbjct: 393 KTLDEEVAYLHLAQLGVKLTKLSDEQASYLGVPVAGPYKPDHYRY 437
>sp|Q27580|SAHH_DROME Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase)
(AdoHcyase)
Length = 432
Score = 260 bits (664), Expect = 3e-69
Identities = 122/162 (75%), Positives = 137/162 (84%)
Frame = +3
Query: 3 IFVTATGCKDIIVGRHFEQMLDDSIVCNIGHFDIEVEAKWLYENCKSKDTIKPQVDRYTL 182
IFVT TGC+DII H +QM DD+IVCNIGHFDIE++ WL N K K +KPQVDRYT+
Sbjct: 271 IFVTTTGCRDIITSVHLQQMPDDAIVCNIGHFDIEIDVDWLNANAKEKVNVKPQVDRYTM 330
Query: 183 KNGRHIILLAEGRLVNLGCAHGHPSFVMSNSFTNQVLAQIELWTKTDQYKVGVYFLPKKL 362
++G+HIILLAEGRLVNLGCAHGHPSFVMSNSFTNQVLAQIELWTK+D+Y VGV+ LPK L
Sbjct: 331 QSGKHIILLAEGRLVNLGCAHGHPSFVMSNSFTNQVLAQIELWTKSDKYAVGVHVLPKIL 390
Query: 363 DEEVAQAHLEHLGVKLTKLTDSQADYLGIPIEGPFKPDHYRY 488
DEEVA HLE LGVKLTKLT+ QA YLG+ GPFKPDHYRY
Sbjct: 391 DEEVASLHLEKLGVKLTKLTEKQATYLGVSQTGPFKPDHYRY 432
>sp|O76757|SAHH_ANOGA Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase)
(AdoHcyase)
Length = 432
Score = 248 bits (632), Expect = 1e-65
Identities = 117/162 (72%), Positives = 130/162 (80%)
Frame = +3
Query: 3 IFVTATGCKDIIVGRHFEQMLDDSIVCNIGHFDIEVEAKWLYENCKSKDTIKPQVDRYTL 182
IFVT TGC DII+G HF M DDSIVCNIGHFD E+ WL EN K IKPQVDRY L
Sbjct: 271 IFVTTTGCTDIIMGEHFLNMKDDSIVCNIGHFDCEINVTWLQENAVEKVNIKPQVDRYRL 330
Query: 183 KNGRHIILLAEGRLVNLGCAHGHPSFVMSNSFTNQVLAQIELWTKTDQYKVGVYFLPKKL 362
NG HIILLAEGRLVNLGCA GH SFVMSNSFTNQVLAQIELWT +QY +GV+ LPKKL
Sbjct: 331 ANGNHIILLAEGRLVNLGCAMGHSSFVMSNSFTNQVLAQIELWTNREQYAIGVHVLPKKL 390
Query: 363 DEEVAQAHLEHLGVKLTKLTDSQADYLGIPIEGPFKPDHYRY 488
D+EVA HL+ LGVKLTKL+ Q +YL +P+EGP+KP+HYRY
Sbjct: 391 DDEVAALHLDKLGVKLTKLSARQPEYLNLPVEGPYKPEHYRY 432
>sp|O13639|SAHH_SCHPO Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase)
(AdoHcyase)
Length = 433
Score = 247 bits (630), Expect = 2e-65
Identities = 117/162 (72%), Positives = 131/162 (80%)
Frame = +3
Query: 3 IFVTATGCKDIIVGRHFEQMLDDSIVCNIGHFDIEVEAKWLYENCKSKDTIKPQVDRYTL 182
IFVT TGC+DII G HF +M +DSIVCNIGHFD+E++ WL N K IKPQVDRY L
Sbjct: 272 IFVTTTGCRDIIRGEHFNEMKEDSIVCNIGHFDVEIDVAWLKANAKDVVNIKPQVDRYEL 331
Query: 183 KNGRHIILLAEGRLVNLGCAHGHPSFVMSNSFTNQVLAQIELWTKTDQYKVGVYFLPKKL 362
KNGRHIILLA+GRLVNLGCA GHPSFVMS SFTNQVLAQI LWT Y +GV+ LPKKL
Sbjct: 332 KNGRHIILLADGRLVNLGCATGHPSFVMSCSFTNQVLAQIALWTDNTSYPLGVHMLPKKL 391
Query: 363 DEEVAQAHLEHLGVKLTKLTDSQADYLGIPIEGPFKPDHYRY 488
DEEVA+ HL LGVKLT LT Q+DYLGIP++GP+K DHYRY
Sbjct: 392 DEEVARLHLGKLGVKLTTLTSVQSDYLGIPVDGPYKADHYRY 433
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,221,561
Number of Sequences: 369166
Number of extensions: 1521753
Number of successful extensions: 3798
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3605
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3698
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5657676120
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)