Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_021_A16
(713 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9ULA0|DNPEP_HUMAN Aspartyl aminopeptidase 213 3e-55
sp|Q9Z2W0|DNPEP_MOUSE Aspartyl aminopeptidase 207 3e-53
sp|Q19087|DNPEP_CAEEL Putative aspartyl aminopeptidase 190 3e-48
sp|O36014|DNPEP_SCHPO Putative aspartyl aminopeptidase 170 4e-42
sp|Q87YC5|APEB_PSESM Probable M18-family aminopeptidase 2 159 9e-39
sp|Q9HYZ3|APEB_PSEAE Probable M18-family aminopeptidase 2 156 6e-38
sp|P38821|DNPEP_YEAST Putative aspartyl aminopeptidase 155 8e-38
sp|Q88M44|APEB_PSEPK Probable M18-family aminopeptidase 2 149 9e-36
sp|P59951|APEB_MYCBO Probable M18-family aminopeptidase 2 129 1e-29
sp|O06634|APEB_MYCTU Probable M18-family aminopeptidase 2 129 1e-29
>sp|Q9ULA0|DNPEP_HUMAN Aspartyl aminopeptidase
Length = 475
Score = 213 bits (543), Expect = 3e-55
Identities = 104/194 (53%), Positives = 144/194 (74%)
Frame = +3
Query: 3 SVSDDTNIRAVCLFDNEEIGSQSAQGAQSAFTELILRRVVNTICQNCGVASFSHYERAIA 182
S++ + ++R V L+DNEE+GS+SAQGAQS TEL+LRR+ + CQ+ + +E AI
Sbjct: 285 SLATEPHVRMVTLYDNEEVGSESAQGAQSLLTELVLRRI-SASCQHP-----TAFEEAIP 338
Query: 183 NSLLISADQAHGVHPNYEEKHERQHKPLPHQGIVLKINSNQRYASNAMTTSILREVANKS 362
S +ISAD AH VHPNY +KHE H+PL H+G V+K+NS QRYASNA++ +++REVANK
Sbjct: 339 KSFMISADMAHAVHPNYLDKHEENHRPLFHKGPVIKVNSKQRYASNAVSEALIREVANKV 398
Query: 363 EVPLQNFVVRQDMACGSTIGPIMSANMGLATVDVGGPQLSMHSCREMTDVSSVEQAVHLF 542
+VPLQ+ +VR D CG+TIGPI+++ +GL +D+G PQL+MHS REM + V Q + LF
Sbjct: 399 KVPLQDLMVRNDTPCGTTIGPILASRLGLRVLDLGSPQLAMHSIREMACTTGVLQTLTLF 458
Query: 543 KGFFNLYPDLSRRV 584
KGFF L+P LS +
Sbjct: 459 KGFFELFPSLSHNL 472
>sp|Q9Z2W0|DNPEP_MOUSE Aspartyl aminopeptidase
Length = 473
Score = 207 bits (526), Expect = 3e-53
Identities = 101/194 (52%), Positives = 138/194 (71%)
Frame = +3
Query: 3 SVSDDTNIRAVCLFDNEEIGSQSAQGAQSAFTELILRRVVNTICQNCGVASFSHYERAIA 182
S++ D ++R V L+DNEE+GS+SAQGAQS TELILRR+ + + +E AI
Sbjct: 283 SLARDPHVRMVTLYDNEEVGSESAQGAQSLLTELILRRI------SASPQRLTAFEEAIP 336
Query: 183 NSLLISADQAHGVHPNYEEKHERQHKPLPHQGIVLKINSNQRYASNAMTTSILREVANKS 362
S +ISAD AH VHPNY +KHE H+P H+G V+K+NS QRYASNA++ S++REVA +
Sbjct: 337 KSFMISADMAHAVHPNYSDKHEENHRPSFHKGPVIKVNSKQRYASNAVSESMIREVAGQV 396
Query: 363 EVPLQNFVVRQDMACGSTIGPIMSANMGLATVDVGGPQLSMHSCREMTDVSSVEQAVHLF 542
VPLQ+ +VR D CG+TIGPI+++ +GL +D+G PQL+MHS RE + V Q + LF
Sbjct: 397 GVPLQDLMVRNDSPCGTTIGPILASRLGLRVLDLGSPQLAMHSIRETACTTGVLQTLTLF 456
Query: 543 KGFFNLYPDLSRRV 584
KGFF L+P +SR +
Sbjct: 457 KGFFELFPSVSRNL 470
>sp|Q19087|DNPEP_CAEEL Putative aspartyl aminopeptidase
Length = 470
Score = 190 bits (483), Expect = 3e-48
Identities = 95/184 (51%), Positives = 123/184 (66%)
Frame = +3
Query: 3 SVSDDTNIRAVCLFDNEEIGSQSAQGAQSAFTELILRRVVNTICQNCGVASFSHYERAIA 182
S +D IR FDNEE+GS SA GA S+FTE +LRR+ S + +E AI
Sbjct: 283 SFKNDPQIRIAACFDNEEVGSDSAMGASSSFTEFVLRRL-------SAGGSTTAFEEAIG 335
Query: 183 NSLLISADQAHGVHPNYEEKHERQHKPLPHQGIVLKINSNQRYASNAMTTSILREVANKS 362
S+LISADQAH HPNY KHE H+P H G+V+K+N NQRYA+ + T + L++VA ++
Sbjct: 336 KSMLISADQAHATHPNYSAKHEENHRPAFHGGVVVKVNVNQRYATTSTTHAALKQVAFEA 395
Query: 363 EVPLQNFVVRQDMACGSTIGPIMSANMGLATVDVGGPQLSMHSCREMTDVSSVEQAVHLF 542
+VPLQ VVR D CGST+GPI++ +GL TVDVG PQL+MHS RE D SS+ QA L+
Sbjct: 396 QVPLQVVVVRNDSPCGSTVGPILATKLGLQTVDVGCPQLAMHSIREFADTSSIYQATTLY 455
Query: 543 KGFF 554
F+
Sbjct: 456 STFY 459
>sp|O36014|DNPEP_SCHPO Putative aspartyl aminopeptidase
Length = 467
Score = 170 bits (430), Expect = 4e-42
Identities = 87/196 (44%), Positives = 129/196 (65%)
Frame = +3
Query: 3 SVSDDTNIRAVCLFDNEEIGSQSAQGAQSAFTELILRRVVNTICQNCGVASFSHYERAIA 182
S+ +++ +R V FD+EEIGS SAQGA+S F +L+R IC+ G S S + ++
Sbjct: 276 SLDNESCVRVVPSFDHEEIGSVSAQGAESTFLPAVLQR----ICE-LGKES-SLFSISMV 329
Query: 183 NSLLISADQAHGVHPNYEEKHERQHKPLPHQGIVLKINSNQRYASNAMTTSILREVANKS 362
S L+SAD AH +HPNY ++E + P ++G V+K+N+NQRY +N+ +L++VA +
Sbjct: 330 KSFLVSADMAHAMHPNYSSRYENSNTPFLNKGTVIKVNANQRYTTNSAGIVLLKKVAQLA 389
Query: 363 EVPLQNFVVRQDMACGSTIGPIMSANMGLATVDVGGPQLSMHSCREMTDVSSVEQAVHLF 542
+VP+Q+FVVR D CGSTIGP ++A G+ T+D+G P LSMHSCREM E AV LF
Sbjct: 390 DVPIQSFVVRNDSPCGSTIGPKLAAMTGMRTLDLGNPMLSMHSCREMCGSKDFEYAVVLF 449
Query: 543 KGFFNLYPDLSRRVTL 590
FF + +L ++ +
Sbjct: 450 SSFFQNFANLEEKIII 465
>sp|Q87YC5|APEB_PSESM Probable M18-family aminopeptidase 2
Length = 429
Score = 159 bits (401), Expect = 9e-39
Identities = 84/182 (46%), Positives = 114/182 (62%)
Frame = +3
Query: 9 SDDTNIRAVCLFDNEEIGSQSAQGAQSAFTELILRRVVNTICQNCGVASFSHYERAIANS 188
SD+T + VC D+EE+GS SA GA A E I++R++ S Y R I S
Sbjct: 253 SDETAL-LVCT-DHEEVGSSSACGADGAMLEQIVQRLL---------PSSEDYVRTIQKS 301
Query: 189 LLISADQAHGVHPNYEEKHERQHKPLPHQGIVLKINSNQRYASNAMTTSILREVANKSEV 368
LLISAD AHG+HPNY +KH+ H P + G V+K+NSNQRYA+N+ T R + EV
Sbjct: 302 LLISADNAHGIHPNYADKHDANHGPKLNAGPVIKVNSNQRYATNSETAGFFRHLCMAEEV 361
Query: 369 PLQNFVVRQDMACGSTIGPIMSANMGLATVDVGGPQLSMHSCREMTDVSSVEQAVHLFKG 548
P+Q+FVVR DM CGSTIGPI ++++G+ TVD+G P +MHS RE+ + V +
Sbjct: 362 PVQSFVVRSDMGCGSTIGPITASHLGIRTVDIGLPTFAMHSIRELAGSHDLAHLVKVLGA 421
Query: 549 FF 554
F+
Sbjct: 422 FY 423
>sp|Q9HYZ3|APEB_PSEAE Probable M18-family aminopeptidase 2
Length = 429
Score = 156 bits (394), Expect = 6e-38
Identities = 82/180 (45%), Positives = 109/180 (60%)
Frame = +3
Query: 15 DTNIRAVCLFDNEEIGSQSAQGAQSAFTELILRRVVNTICQNCGVASFSHYERAIANSLL 194
D N VC D+EE+GS S GA F E +LRR++ + RAI SLL
Sbjct: 254 DENCILVCT-DHEEVGSCSHCGADGPFLEQVLRRLL---------PEGDAFSRAIQRSLL 303
Query: 195 ISADQAHGVHPNYEEKHERQHKPLPHQGIVLKINSNQRYASNAMTTSILREVANKSEVPL 374
+SAD AHGVHPNY ++H+ H P + G V+KINSNQRYA+N+ T R + SEVP+
Sbjct: 304 VSADNAHGVHPNYADRHDANHGPALNGGPVIKINSNQRYATNSETAGFFRHLCQDSEVPV 363
Query: 375 QNFVVRQDMACGSTIGPIMSANMGLATVDVGGPQLSMHSCREMTDVSSVEQAVHLFKGFF 554
Q+FV R DM CGSTIGPI ++ +G+ TVD+G P +MHS RE+ + V + F+
Sbjct: 364 QSFVTRSDMGCGSTIGPITASQVGVRTVDIGLPTFAMHSIRELAGSHDLAHLVKVLGAFY 423
>sp|P38821|DNPEP_YEAST Putative aspartyl aminopeptidase
Length = 490
Score = 155 bits (393), Expect = 8e-38
Identities = 87/200 (43%), Positives = 121/200 (60%), Gaps = 5/200 (2%)
Frame = +3
Query: 6 VSDDTNIRAVCLFDNEEIGSQSAQGAQSAFTELILRRVVNTICQNCGVASFSH-YERAI- 179
+ ++ IR + FD+EEIGS SAQGA S F IL R+ +I + G + AI
Sbjct: 293 IDRESGIRLMACFDHEEIGSSSAQGADSNFLPNILERL--SILKGDGSDQTKPLFHSAIL 350
Query: 180 ---ANSLLISADQAHGVHPNYEEKHERQHKPLPHQGIVLKINSNQRYASNAMTTSILREV 350
A S +S+D AH VHPNY K+E QHKPL G V+KIN+NQRY +N+ +++ +
Sbjct: 351 ETSAKSFFLSSDVAHAVHPNYANKYESQHKPLLGGGPVIKINANQRYMTNSPGLVLVKRL 410
Query: 351 ANKSEVPLQNFVVRQDMACGSTIGPIMSANMGLATVDVGGPQLSMHSCREMTDVSSVEQA 530
A ++VPLQ FVV D CGSTIGPI+++ G+ T+D+G P LSMHS RE + +E
Sbjct: 411 AEAAKVPLQLFVVANDSPCGSTIGPILASKTGIRTLDLGNPVLSMHSIRETGGSADLEFQ 470
Query: 531 VHLFKGFFNLYPDLSRRVTL 590
+ LFK FF Y + + +
Sbjct: 471 IKLFKEFFERYTSIESEIVV 490
>sp|Q88M44|APEB_PSEPK Probable M18-family aminopeptidase 2
Length = 429
Score = 149 bits (375), Expect = 9e-36
Identities = 79/182 (43%), Positives = 111/182 (60%)
Frame = +3
Query: 9 SDDTNIRAVCLFDNEEIGSQSAQGAQSAFTELILRRVVNTICQNCGVASFSHYERAIANS 188
SD+T + VC D+EE+GS SA GA E L+R++ Y R + S
Sbjct: 253 SDETCV-LVCN-DHEEVGSCSACGADGPMLEQTLQRLL---------PDGDTYVRTVQRS 301
Query: 189 LLISADQAHGVHPNYEEKHERQHKPLPHQGIVLKINSNQRYASNAMTTSILREVANKSEV 368
L++SAD AHGVHPNY +KH+ H P + G V+K+N+NQRYA+N+ T R + EV
Sbjct: 302 LMVSADNAHGVHPNYADKHDGNHGPKLNAGPVIKVNNNQRYATNSETAGFFRHLCMAEEV 361
Query: 369 PLQNFVVRQDMACGSTIGPIMSANMGLATVDVGGPQLSMHSCREMTDVSSVEQAVHLFKG 548
P+Q+FVVR DM CGSTIGPI ++++G+ TVD+G P +MHS RE+ + V +
Sbjct: 362 PVQSFVVRSDMGCGSTIGPITASHLGVRTVDIGLPTFAMHSIRELCGSHDLAHLVKVLTA 421
Query: 549 FF 554
F+
Sbjct: 422 FY 423
>sp|P59951|APEB_MYCBO Probable M18-family aminopeptidase 2
Length = 433
Score = 129 bits (323), Expect = 1e-29
Identities = 68/176 (38%), Positives = 100/176 (56%), Gaps = 3/176 (1%)
Frame = +3
Query: 24 IRAVCLFDNEEIGSQSAQGAQSAFTELILRRVVNTICQNCGVASFSHYERAIANSLLISA 203
+ + +FD+EE+GS S GAQS +L R+V + + R + S+L SA
Sbjct: 255 VPVLAIFDHEEVGSASGHGAQSDLLSSVLERIVLA-----AGGTREDFLRRLTTSMLASA 309
Query: 204 DQAHGVHPNYEEKHERQHKPLPHQGIVLKINSNQRYASNAMTTSILREVANKSEVPLQNF 383
D AH HPNY ++HE H + G VLK++ N RYA++ T + ++ VP+Q +
Sbjct: 310 DMAHATHPNYPDRHEPSHPIEVNAGPVLKVHPNLRYATDGRTAAAFALACQRAGVPMQRY 369
Query: 384 VVRQDMACGSTIGPIMSANMGLATVDVGGPQLSMHSCREMT---DVSSVEQAVHLF 542
R D+ CGSTIGP+ +A G+ TVDVG QL+MHS RE+ DV++ A+ F
Sbjct: 370 EHRADLPCGSTIGPLAAARTGIPTVDVGAAQLAMHSARELMGAHDVAAYSAALQAF 425
>sp|O06634|APEB_MYCTU Probable M18-family aminopeptidase 2
Length = 433
Score = 129 bits (323), Expect = 1e-29
Identities = 68/176 (38%), Positives = 100/176 (56%), Gaps = 3/176 (1%)
Frame = +3
Query: 24 IRAVCLFDNEEIGSQSAQGAQSAFTELILRRVVNTICQNCGVASFSHYERAIANSLLISA 203
+ + +FD+EE+GS S GAQS +L R+V + + R + S+L SA
Sbjct: 255 VPVLAIFDHEEVGSASGHGAQSDLLSSVLERIVLA-----AGGTREDFLRRLTTSMLASA 309
Query: 204 DQAHGVHPNYEEKHERQHKPLPHQGIVLKINSNQRYASNAMTTSILREVANKSEVPLQNF 383
D AH HPNY ++HE H + G VLK++ N RYA++ T + ++ VP+Q +
Sbjct: 310 DMAHATHPNYPDRHEPSHPIEVNAGPVLKVHPNLRYATDGRTAAAFALACQRAGVPMQRY 369
Query: 384 VVRQDMACGSTIGPIMSANMGLATVDVGGPQLSMHSCREMT---DVSSVEQAVHLF 542
R D+ CGSTIGP+ +A G+ TVDVG QL+MHS RE+ DV++ A+ F
Sbjct: 370 EHRADLPCGSTIGPLAAARTGIPTVDVGAAQLAMHSARELMGAHDVAAYSAALQAF 425
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82,424,294
Number of Sequences: 369166
Number of extensions: 1700278
Number of successful extensions: 4342
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4130
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4324
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6316483550
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)