Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_021_A06
(860 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5G265|NETR_SAGLB Neurotrypsin precursor 91 4e-18
sp|O08762|NETR_MOUSE Neurotrypsin precursor (Motopsin) (Bra... 90 7e-18
sp|Q5G269|NETR_PONPY Neurotrypsin precursor 88 3e-17
sp|Q5G268|NETR_HYLLE Neurotrypsin precursor 88 3e-17
sp|P56730|NETR_HUMAN Neurotrypsin precursor (Motopsin) (Ley... 88 3e-17
sp|Q5G271|NETR_PANTR Neurotrypsin precursor 87 5e-17
sp|Q5G270|NETR_GORGO Neurotrypsin precursor 87 6e-17
sp|Q5G266|NETR_TRAPH Neurotrypsin precursor 87 8e-17
sp|Q5G267|NETR_MACMU Neurotrypsin precursor 87 8e-17
sp|P03952|KLKB1_HUMAN Plasma kallikrein precursor (Plasma p... 85 3e-16
>sp|Q5G265|NETR_SAGLB Neurotrypsin precursor
Length = 875
Score = 90.9 bits (224), Expect = 4e-18
Identities = 79/293 (26%), Positives = 125/293 (42%), Gaps = 30/293 (10%)
Frame = +1
Query: 22 YGFGNKNFLLDYLYCNGNEDSIDDCPWQYWRLRNCYGNDVAGVYC-------AGNAS--- 171
+G G +D + C GNE S+ DC Q NC ++ AGV C +GN++
Sbjct: 555 FGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICDYFGKKASGNSNKES 614
Query: 172 ----CGEVYTEERNQLSSFGYNTTFGANPWQVRIIPRVANE----WCSGTIINKNWVLTS 327
CG R + G N+ G PWQV + + ++ C T+++ WVLT+
Sbjct: 615 LSSVCGLRLLHRRQKRIIGGKNSLRGGWPWQVSLRLKSSHRDGRLLCGATLLSSCWVLTA 674
Query: 328 ANCFTMSYDNFXXXXXXXXXXXXXXNWAYTNNI--NSVFIHPQYSAVTGDYNLALVKTSP 501
A+CF ++ + I + IH +Y + DY++ALV+
Sbjct: 675 AHCFKRYGNSTRNYAVRVGDYHTLVPEEFEEEIGVQEIVIHREYRPDSSDYDIALVRLQG 734
Query: 502 -----VAFDINVQPACLPSKNLVP--NSLDCITAGWNHKLETNSRPLLGKSVNLYNTTNC 660
F+ +V PACLP P + +C GW + SR L +++L C
Sbjct: 735 PEEQCARFNSHVLPACLPLWRERPQKTASNCYITGWGDTGQAYSRTLQQAAIHLLPKRFC 794
Query: 661 KSLTQFDDDKLARYFCSDNNMDSSAI--FNGESGGPLICSIDG-SKVIAGVVS 810
+ ++ R C+ N + + G+SGGPL+C G S V+ GV S
Sbjct: 795 EE--RYKGRFTGRMLCAGNLHEHKHVDSCQGDSGGPLMCERPGESWVVYGVTS 845
Score = 41.6 bits (96), Expect = 0.003
Identities = 19/45 (42%), Positives = 25/45 (55%)
Frame = +1
Query: 22 YGFGNKNFLLDYLYCNGNEDSIDDCPWQYWRLRNCYGNDVAGVYC 156
+G G+ +LD + C GNE SI+ CP W NC + AGV C
Sbjct: 335 FGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC 379
>sp|O08762|NETR_MOUSE Neurotrypsin precursor (Motopsin) (Brain-specific serine protease 3)
(BSSP-3)
Length = 761
Score = 90.1 bits (222), Expect = 7e-18
Identities = 82/293 (27%), Positives = 119/293 (40%), Gaps = 30/293 (10%)
Frame = +1
Query: 22 YGFGNKNFLLDYLYCNGNEDSIDDCPWQYWRLRNCYGNDVAGVYC---------AGN--- 165
+G G +D + C GNE ++ DC Q NC ++ AGV C +GN
Sbjct: 441 FGEGKGPIHMDNVKCTGNEKALADCVKQDIGRHNCRHSEDAGVICDYLEKKASSSGNKEM 500
Query: 166 --ASCGEVYTEERNQLSSFGYNTTFGANPWQVRIIPRVANE----WCSGTIINKNWVLTS 327
+ CG R + G N+ GA PWQ + R A+ C T+++ WVLT+
Sbjct: 501 LSSGCGLRLLHRRQKRIIGGNNSLRGAWPWQASLRLRSAHGDGRLLCGATLLSSCWVLTA 560
Query: 328 ANCFTMSYDNFXXXXXXXXXXXXXXNWAYTNNI--NSVFIHPQYSAVTGDYNLALVKTSP 501
A+CF +N + I + IH Y DY++ALV+
Sbjct: 561 AHCFKRYGNNSRSYAVRVGDYHTLVPEEFEQEIGVQQIVIHRNYRPDRSDYDIALVRLQG 620
Query: 502 -----VAFDINVQPACLPSKNLVP--NSLDCITAGWNHKLETNSRPLLGKSVNLYNTTNC 660
+V PACLP P + +C GW SR L +V L C
Sbjct: 621 PGEQCARLSTHVLPACLPLWRERPQKTASNCHITGWGDTGRAYSRTLQQAAVPLLPKRFC 680
Query: 661 KSLTQFDDDKLARYFCSDNNMDSSAI--FNGESGGPLIC-SIDGSKVIAGVVS 810
K ++ R C+ N + + + G+SGGPL+C D S V+ GV S
Sbjct: 681 KE--RYKGLFTGRMLCAGNLQEDNRVDSCQGDSGGPLMCEKPDESWVVYGVTS 731
Score = 42.7 bits (99), Expect = 0.001
Identities = 20/45 (44%), Positives = 25/45 (55%)
Frame = +1
Query: 22 YGFGNKNFLLDYLYCNGNEDSIDDCPWQYWRLRNCYGNDVAGVYC 156
+G G+ LLD + C GNE SI+ CP W NC + AGV C
Sbjct: 221 FGEGSGPILLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC 265
>sp|Q5G269|NETR_PONPY Neurotrypsin precursor
Length = 877
Score = 88.2 bits (217), Expect = 3e-17
Identities = 80/294 (27%), Positives = 122/294 (41%), Gaps = 31/294 (10%)
Frame = +1
Query: 22 YGFGNKNFLLDYLYCNGNEDSIDDCPWQYWRLRNCYGNDVAGVYC-------AGNAS--- 171
+G G +D + C GNE S+ DC Q NC ++ AGV C +GN++
Sbjct: 557 FGEGKGPIHVDNVRCTGNERSLADCIKQDIGRHNCRHSEDAGVICDYFGKKASGNSNKES 616
Query: 172 ----CGEVYTEERNQLSSFGYNTTFGANPWQVRIIPRVANE----WCSGTIINKNWVLTS 327
CG R + G N+ G PWQV + + ++ C T+++ WVLT+
Sbjct: 617 LSSVCGLRLLHRRQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTA 676
Query: 328 ANCFTMSYDNF---XXXXXXXXXXXXXXNWAYTNNINSVFIHPQYSAVTGDYNLALVKTS 498
A+CF Y N + + + IH +Y + DY++ALV+
Sbjct: 677 AHCF-KRYGNSTRNYAVRVGDYHTLVPEEFEEEVGVQQIVIHREYRPDSSDYDIALVRLQ 735
Query: 499 P-----VAFDINVQPACLPSKNLVP--NSLDCITAGWNHKLETNSRPLLGKSVNLYNTTN 657
F +V PACLP P + +C GW SR L ++ L
Sbjct: 736 GPEEQCARFSSHVLPACLPLWRERPQKTASNCYITGWGDTGRAYSRTLQQAAIPLLPKRF 795
Query: 658 CKSLTQFDDDKLARYFCSDNNMDSSAI--FNGESGGPLICSIDG-SKVIAGVVS 810
C+ ++ R C+ N + + G+SGGPL+C G S V+ GV S
Sbjct: 796 CEE--RYKGXFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTS 847
Score = 41.6 bits (96), Expect = 0.003
Identities = 19/45 (42%), Positives = 25/45 (55%)
Frame = +1
Query: 22 YGFGNKNFLLDYLYCNGNEDSIDDCPWQYWRLRNCYGNDVAGVYC 156
+G G+ +LD + C GNE SI+ CP W NC + AGV C
Sbjct: 337 FGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC 381
>sp|Q5G268|NETR_HYLLE Neurotrypsin precursor
Length = 875
Score = 88.2 bits (217), Expect = 3e-17
Identities = 79/293 (26%), Positives = 122/293 (41%), Gaps = 30/293 (10%)
Frame = +1
Query: 22 YGFGNKNFLLDYLYCNGNEDSIDDCPWQYWRLRNCYGNDVAGVYC-------AGNAS--- 171
+G G +D + C GNE S+ DC Q NC ++ AGV C +GN++
Sbjct: 555 FGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICDYFGKKASGNSNKES 614
Query: 172 ----CGEVYTEERNQLSSFGYNTTFGANPWQVRIIPRVANE----WCSGTIINKNWVLTS 327
CG R + G N+ G PWQV + + ++ C T+++ WVLT+
Sbjct: 615 LSSVCGLRLLHRRQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTA 674
Query: 328 ANCFTMSYDNFXXXXXXXXXXXXXXNWAYTNNI--NSVFIHPQYSAVTGDYNLALVKTSP 501
A+CF ++ + I + IH +Y + DY++ALV+
Sbjct: 675 AHCFKRYGNSTRNYAVRVGDYHTLVPEEFEEEIGVQQIVIHREYRPDSSDYDIALVRLQG 734
Query: 502 -----VAFDINVQPACLPSKNLVP--NSLDCITAGWNHKLETNSRPLLGKSVNLYNTTNC 660
F +V PACLP P + +C GW SR L ++ L C
Sbjct: 735 PEEQCARFSSHVLPACLPLWRERPQKTASNCYITGWGDTGRAYSRTLQQAAIPLLPKRFC 794
Query: 661 KSLTQFDDDKLARYFCSDNNMDSSAI--FNGESGGPLICSIDG-SKVIAGVVS 810
+ ++ R C+ N + + G+SGGPL+C G S V+ GV S
Sbjct: 795 EE--RYKGRFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTS 845
Score = 41.6 bits (96), Expect = 0.003
Identities = 19/45 (42%), Positives = 25/45 (55%)
Frame = +1
Query: 22 YGFGNKNFLLDYLYCNGNEDSIDDCPWQYWRLRNCYGNDVAGVYC 156
+G G+ +LD + C GNE SI+ CP W NC + AGV C
Sbjct: 335 FGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC 379
>sp|P56730|NETR_HUMAN Neurotrypsin precursor (Motopsin) (Leydin)
Length = 875
Score = 87.8 bits (216), Expect = 3e-17
Identities = 81/297 (27%), Positives = 122/297 (41%), Gaps = 34/297 (11%)
Frame = +1
Query: 22 YGFGNKNFLLDYLYCNGNEDSIDDCPWQYWRLRNCYGNDVAGVYC-------AGNAS--- 171
+G G +D + C GNE S+ DC Q NC ++ AGV C +GN++
Sbjct: 555 FGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICDYFGKKASGNSNKES 614
Query: 172 ----CGEVYTEERNQLSSFGYNTTFGANPWQVRIIPRVANE----WCSGTIINKNWVLTS 327
CG R + G N+ G PWQV + + ++ C T+++ WVLT+
Sbjct: 615 LSSVCGLRLLHRRQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTA 674
Query: 328 ANCF------TMSYDNFXXXXXXXXXXXXXXNWAYTNNINSVFIHPQYSAVTGDYNLALV 489
A+CF T SY + + + IH +Y DY++ALV
Sbjct: 675 AHCFKRYGNSTRSY----AVRVGDYHTLVPEEFEEEIGVQQIVIHREYRPDRSDYDIALV 730
Query: 490 KTSP-----VAFDINVQPACLPSKNLVP--NSLDCITAGWNHKLETNSRPLLGKSVNLYN 648
+ F +V PACLP P + +C GW SR L ++ L
Sbjct: 731 RLQGPEEQCARFSSHVLPACLPLWRERPQKTASNCYITGWGDTGRAYSRTLQQAAIPLLP 790
Query: 649 TTNCKSLTQFDDDKLARYFCSDNNMDSSAI--FNGESGGPLICSIDG-SKVIAGVVS 810
C+ ++ R C+ N + + G+SGGPL+C G S V+ GV S
Sbjct: 791 KRFCEE--RYKGRFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTS 845
Score = 41.6 bits (96), Expect = 0.003
Identities = 19/45 (42%), Positives = 25/45 (55%)
Frame = +1
Query: 22 YGFGNKNFLLDYLYCNGNEDSIDDCPWQYWRLRNCYGNDVAGVYC 156
+G G+ +LD + C GNE SI+ CP W NC + AGV C
Sbjct: 335 FGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC 379
>sp|Q5G271|NETR_PANTR Neurotrypsin precursor
Length = 875
Score = 87.4 bits (215), Expect = 5e-17
Identities = 81/297 (27%), Positives = 122/297 (41%), Gaps = 34/297 (11%)
Frame = +1
Query: 22 YGFGNKNFLLDYLYCNGNEDSIDDCPWQYWRLRNCYGNDVAGVYC-------AGNAS--- 171
+G G +D + C GNE S+ DC Q NC ++ AGV C +GN++
Sbjct: 555 FGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICDYFGKKASGNSNKES 614
Query: 172 ----CGEVYTEERNQLSSFGYNTTFGANPWQVRIIPRVANE----WCSGTIINKNWVLTS 327
CG R + G N+ G PWQV + + ++ C T+++ WVLT+
Sbjct: 615 LSSVCGLRLLHRRQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTA 674
Query: 328 ANCF------TMSYDNFXXXXXXXXXXXXXXNWAYTNNINSVFIHPQYSAVTGDYNLALV 489
A+CF T SY + + + IH +Y DY++ALV
Sbjct: 675 AHCFKRYGNSTRSY----AVRVGDYHTLVPEEFEEEIGVQQIVIHREYRPDRSDYDIALV 730
Query: 490 KTSP-----VAFDINVQPACLPSKNLVP--NSLDCITAGWNHKLETNSRPLLGKSVNLYN 648
+ F +V PACLP P + +C GW SR L ++ L
Sbjct: 731 RLQGPEEQCARFSSHVLPACLPLWRERPQKTASNCYITGWGDTGRAYSRTLQQAAIPLLP 790
Query: 649 TTNCKSLTQFDDDKLARYFCSDNNMDSSAI--FNGESGGPLICSIDG-SKVIAGVVS 810
C+ ++ R C+ N + + G+SGGPL+C G S V+ GV S
Sbjct: 791 KRFCEE--RYKRRFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTS 845
Score = 41.6 bits (96), Expect = 0.003
Identities = 19/45 (42%), Positives = 25/45 (55%)
Frame = +1
Query: 22 YGFGNKNFLLDYLYCNGNEDSIDDCPWQYWRLRNCYGNDVAGVYC 156
+G G+ +LD + C GNE SI+ CP W NC + AGV C
Sbjct: 335 FGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC 379
>sp|Q5G270|NETR_GORGO Neurotrypsin precursor
Length = 876
Score = 87.0 bits (214), Expect = 6e-17
Identities = 79/293 (26%), Positives = 120/293 (40%), Gaps = 30/293 (10%)
Frame = +1
Query: 22 YGFGNKNFLLDYLYCNGNEDSIDDCPWQYWRLRNCYGNDVAGVYC-------AGNAS--- 171
+G G +D + C GNE S+ DC Q NC ++ AGV C +GN++
Sbjct: 556 FGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICDYFGKKASGNSNKES 615
Query: 172 ----CGEVYTEERNQLSSFGYNTTFGANPWQVRIIPRV----ANEWCSGTIINKNWVLTS 327
CG R + G N+ G PWQV + + C T+++ WVLT+
Sbjct: 616 LSSVCGLRLLHRRQKRIIGGKNSLRGGWPWQVSLRLKSYHGDGRLLCGATLLSSCWVLTA 675
Query: 328 ANCFTMSYDNFXXXXXXXXXXXXXXNWAYTNNI--NSVFIHPQYSAVTGDYNLALVKTSP 501
A+CF ++ + I + IH +Y + DY++ALV+
Sbjct: 676 AHCFKRYGNSTRNYAVRVGDYHTLVPEEFEEEIGVQQIVIHREYRPDSSDYDIALVRLQG 735
Query: 502 -----VAFDINVQPACLPSKNLVP--NSLDCITAGWNHKLETNSRPLLGKSVNLYNTTNC 660
F +V PACLP P + +C GW SR L ++ L C
Sbjct: 736 PEEQCARFSSHVLPACLPLWRERPQKTASNCYITGWGDTGRAYSRTLQQAAIPLLPKRFC 795
Query: 661 KSLTQFDDDKLARYFCSDNNMDSSAI--FNGESGGPLICSIDG-SKVIAGVVS 810
+ ++ R C+ N + + G+SGGPL+C G S V+ GV S
Sbjct: 796 EE--RYKGRFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTS 846
Score = 41.6 bits (96), Expect = 0.003
Identities = 19/45 (42%), Positives = 25/45 (55%)
Frame = +1
Query: 22 YGFGNKNFLLDYLYCNGNEDSIDDCPWQYWRLRNCYGNDVAGVYC 156
+G G+ +LD + C GNE SI+ CP W NC + AGV C
Sbjct: 336 FGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC 380
>sp|Q5G266|NETR_TRAPH Neurotrypsin precursor
Length = 875
Score = 86.7 bits (213), Expect = 8e-17
Identities = 78/293 (26%), Positives = 121/293 (41%), Gaps = 30/293 (10%)
Frame = +1
Query: 22 YGFGNKNFLLDYLYCNGNEDSIDDCPWQYWRLRNCYGNDVAGVYC-------AGNAS--- 171
+G G +D + C GNE S+ DC Q NC ++ AGV C +GN++
Sbjct: 555 FGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICDYFGKKASGNSNKES 614
Query: 172 ----CGEVYTEERNQLSSFGYNTTFGANPWQVRIIPRVANE----WCSGTIINKNWVLTS 327
CG R + G N+ G PWQV + + ++ C T+++ WVLT+
Sbjct: 615 LSSVCGLRLLHRRQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTA 674
Query: 328 ANCFTMSYDNFXXXXXXXXXXXXXXNWAYTNNI--NSVFIHPQYSAVTGDYNLALVKTSP 501
A+CF ++ + I + IH +Y + DY++ALV+
Sbjct: 675 AHCFKRYGNSTRNYAVRVGDYHTLVPEEFEEEIGVQQIVIHREYRPDSSDYDIALVRLQG 734
Query: 502 -----VAFDINVQPACLPSKNLVP--NSLDCITAGWNHKLETNSRPLLGKSVNLYNTTNC 660
F +V PACLP P + +C GW SR L ++ L C
Sbjct: 735 PEEQCARFSSHVLPACLPFWRERPQKTASNCYITGWGDTGRAYSRTLQQAAIPLLPKRFC 794
Query: 661 KSLTQFDDDKLARYFCSDNNMDSSAI--FNGESGGPLICSIDG-SKVIAGVVS 810
+ ++ R C+ N + + G+SGGPL+C G S + GV S
Sbjct: 795 EE--RYKGRFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWAVYGVTS 845
Score = 41.6 bits (96), Expect = 0.003
Identities = 19/45 (42%), Positives = 25/45 (55%)
Frame = +1
Query: 22 YGFGNKNFLLDYLYCNGNEDSIDDCPWQYWRLRNCYGNDVAGVYC 156
+G G+ +LD + C GNE SI+ CP W NC + AGV C
Sbjct: 335 FGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC 379
>sp|Q5G267|NETR_MACMU Neurotrypsin precursor
Length = 875
Score = 86.7 bits (213), Expect = 8e-17
Identities = 78/293 (26%), Positives = 121/293 (41%), Gaps = 30/293 (10%)
Frame = +1
Query: 22 YGFGNKNFLLDYLYCNGNEDSIDDCPWQYWRLRNCYGNDVAGVYC-------AGNAS--- 171
+G G +D + C GNE S+ DC Q NC ++ AGV C +GN++
Sbjct: 555 FGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICDYFGKKASGNSNKES 614
Query: 172 ----CGEVYTEERNQLSSFGYNTTFGANPWQVRIIPRVANE----WCSGTIINKNWVLTS 327
CG R + G N+ G PWQV + + ++ C T+++ WVLT+
Sbjct: 615 LSSVCGLRLLHRRQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTA 674
Query: 328 ANCFTMSYDNFXXXXXXXXXXXXXXNWAYTNNI--NSVFIHPQYSAVTGDYNLALVKTSP 501
A+CF ++ + I + IH +Y + DY++ALV+
Sbjct: 675 AHCFKRYGNSTRNYAVRVGDYHTLVPEEFEEEIGVQQIVIHREYRPDSSDYDIALVRLQG 734
Query: 502 -----VAFDINVQPACLPSKNLVP--NSLDCITAGWNHKLETNSRPLLGKSVNLYNTTNC 660
F +V PACLP P + +C GW SR L ++ L C
Sbjct: 735 PEEQCARFSSHVLPACLPFWRERPQKTASNCYITGWGDTGRAYSRTLQQAAIPLLPKRFC 794
Query: 661 KSLTQFDDDKLARYFCSDNNMDSSAI--FNGESGGPLICSIDG-SKVIAGVVS 810
+ ++ R C+ N + + G+SGGPL+C G S + GV S
Sbjct: 795 EE--RYKGRFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWAVYGVTS 845
Score = 41.6 bits (96), Expect = 0.003
Identities = 19/45 (42%), Positives = 25/45 (55%)
Frame = +1
Query: 22 YGFGNKNFLLDYLYCNGNEDSIDDCPWQYWRLRNCYGNDVAGVYC 156
+G G+ +LD + C GNE SI+ CP W NC + AGV C
Sbjct: 335 FGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC 379
>sp|P03952|KLKB1_HUMAN Plasma kallikrein precursor (Plasma prekallikrein) (Kininogenin)
(Fletcher factor) [Contains: Plasma kallikrein heavy
chain; Plasma kallikrein light chain]
Length = 638
Score = 84.7 bits (208), Expect = 3e-16
Identities = 64/255 (25%), Positives = 110/255 (43%), Gaps = 8/255 (3%)
Frame = +1
Query: 118 RNCYGNDVAGVYCAGNASCGE--VYTEERNQLSSFGYNTTFGANPWQVRIIPRVANE--W 285
R YG + Y + G+ V T + + G N+++G PWQV + ++ +
Sbjct: 359 RIAYGTQGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHL 418
Query: 286 CSGTIINKNWVLTSANCFT-MSYDNFXXXXXXXXXXXXXXNWAYTNNINSVFIHPQYSAV 462
C G++I WVLT+A+CF + + + I + IH Y
Sbjct: 419 CGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVS 478
Query: 463 TGDYNLALVKT-SPVAFDINVQPACLPSKNLVPNSL-DCITAGWNHKLETNSRPLLGKSV 636
G++++AL+K +P+ + +P CLPSK +C GW E + + V
Sbjct: 479 EGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKV 538
Query: 637 NLYNTTNCKSLTQFDDDKLA-RYFCSDNNMDSSAIFNGESGGPLICSIDGSKVIAGVVSK 813
N+ TN + ++ D K+ R C+ G+SGGPL+C +G + G+ S
Sbjct: 539 NIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSW 598
Query: 814 SINSARATSIRLFTR 858
AR ++T+
Sbjct: 599 GEGCARREQPGVYTK 613
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 105,681,954
Number of Sequences: 369166
Number of extensions: 2239834
Number of successful extensions: 6470
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5578
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6006
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8534739105
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)