Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_020_P06
(765 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8R3I3|COG6_MOUSE Conserved oligomeric Golgi complex com... 178 1e-44
sp|Q9Y2V7|COG6_HUMAN Conserved oligomeric Golgi complex com... 177 2e-44
sp|Q9V564|COG6_DROME Putative conserved oligomeric Golgi co... 138 1e-32
sp|Q21270|COG6_CAEEL Putative conserved oligomeric Golgi co... 62 1e-09
sp|Q7NDH1|DNAK_GLOVI Chaperone protein dnaK (Heat shock pro... 31 4.2
sp|P51711|REP_BPHP1 Replication protein 30 5.5
sp|P31069|KCH_ECOLI Putative potassium channel protein 30 9.3
sp|Q18297|TRPA1_CAEEL Transient receptor potential cation c... 30 9.3
>sp|Q8R3I3|COG6_MOUSE Conserved oligomeric Golgi complex component 6
Length = 605
Score = 178 bits (452), Expect = 1e-44
Identities = 87/231 (37%), Positives = 147/231 (63%)
Frame = +2
Query: 2 LEKIETPQHNLAPTPAIQKTLRLLEEILTAQDVSMLPTSSNKSDLQQVLYTLIDPLLQYC 181
++K+E P +L P+ A+ +TL LL +IL + D S++P + ++D QVL +DPLLQ C
Sbjct: 374 MDKVELPPPDLGPSSALSQTLTLLRDILASHDSSVVPLDARQADFVQVLSCALDPLLQMC 433
Query: 182 CLSASSISPVEAAVYLCNCLYLYQTALAKFEYTDAKLEQIQGQLDANVDSLVSFQAGFVI 361
+SAS++ + A ++ N LY+ +T LA FE+TD +LE +Q Q++A++D+L++ QA +V+
Sbjct: 434 TVSASNLGTADMATFMVNSLYMMKTTLALFEFTDRRLEMLQFQIEAHLDTLINEQASYVL 493
Query: 362 RSSGLSVLYELVEQDNNDNNDIVLSDRVPELSVKKIMAQFDLFLAHPDTLMMPQLALLSS 541
GLS +Y ++Q D + + +++K MAQFD +L+ PD L+MPQL L S
Sbjct: 494 TRVGLSYIYNTIQQHRPDQGSLANMPNLDAVALKAAMAQFDRYLSAPDHLLMPQLNSLLS 553
Query: 542 IKLKDLIRRRSNDLVHSAYTRLFNAIRKPASGYTDPIVLVPRTPDQVADLI 694
+K+ I ++S +L+ AY + A+ P + Y DP ++ R+P+QV L+
Sbjct: 554 ATVKEQIIKQSTELICRAYAEVHAAVMNPDNAYKDPENILHRSPEQVKTLL 604
>sp|Q9Y2V7|COG6_HUMAN Conserved oligomeric Golgi complex component 6
Length = 605
Score = 177 bits (450), Expect = 2e-44
Identities = 86/231 (37%), Positives = 147/231 (63%)
Frame = +2
Query: 2 LEKIETPQHNLAPTPAIQKTLRLLEEILTAQDVSMLPTSSNKSDLQQVLYTLIDPLLQYC 181
++K+E P +L P+ A+ +TL LL E+L + D S++P + ++D QVL ++DPLLQ C
Sbjct: 374 MDKVELPPPDLGPSSALNQTLMLLREVLASHDSSVVPLDARQADFVQVLSCVLDPLLQMC 433
Query: 182 CLSASSISPVEAAVYLCNCLYLYQTALAKFEYTDAKLEQIQGQLDANVDSLVSFQAGFVI 361
+SAS++ + A ++ N LY+ +T LA FE+TD +LE +Q Q++A++D+L++ QA +V+
Sbjct: 434 TVSASNLGTADMATFMVNSLYMMKTTLALFEFTDRRLEMLQFQIEAHLDTLINEQASYVL 493
Query: 362 RSSGLSVLYELVEQDNNDNNDIVLSDRVPELSVKKIMAQFDLFLAHPDTLMMPQLALLSS 541
GLS +Y V+Q + + + +++K M QFD +L+ PD L++PQL L S
Sbjct: 494 TRVGLSYIYNTVQQHKPEQGSLANMPNLDSVTLKAAMVQFDRYLSAPDNLLIPQLNFLLS 553
Query: 542 IKLKDLIRRRSNDLVHSAYTRLFNAIRKPASGYTDPIVLVPRTPDQVADLI 694
+K+ I ++S +LV AY ++ A+ P + Y DP ++ R+P QV L+
Sbjct: 554 ATVKEQIVKQSTELVCRAYGEVYAAVMNPINEYKDPENILHRSPQQVQTLL 604
>sp|Q9V564|COG6_DROME Putative conserved oligomeric Golgi complex component 6
Length = 630
Score = 138 bits (348), Expect = 1e-32
Identities = 71/228 (31%), Positives = 136/228 (59%)
Frame = +2
Query: 11 IETPQHNLAPTPAIQKTLRLLEEILTAQDVSMLPTSSNKSDLQQVLYTLIDPLLQYCCLS 190
+E PQ +L P P++ + L +L+EIL+ + ++D+ +++ +IDPLLQ S
Sbjct: 413 LEPPQRDLVPPPSVARLLNMLKEILSVATM----VDGRQADITKIVSCVIDPLLQSVQES 468
Query: 191 ASSISPVEAAVYLCNCLYLYQTALAKFEYTDAKLEQIQGQLDANVDSLVSFQAGFVIRSS 370
A+ + V+ VYL NCL+ Q++LA +EY D ++E++Q Q DA +D+L S QA ++ +
Sbjct: 469 AAHLPTVDMGVYLLNCLHHMQSSLAVYEYMDERVERLQAQSDAQLDTLTSEQASSLVANL 528
Query: 371 GLSVLYELVEQDNNDNNDIVLSDRVPELSVKKIMAQFDLFLAHPDTLMMPQLALLSSIKL 550
L +Y +++ + + ++ +K M++ D FL PD L++PQ+ L+ S
Sbjct: 529 NLGPIYAILQSNQS---------KIETNLLKIFMSKMDAFLELPDVLLLPQVQLIMSSSH 579
Query: 551 KDLIRRRSNDLVHSAYTRLFNAIRKPASGYTDPIVLVPRTPDQVADLI 694
+ +++RS +++ + Y +++ + PA+G+ P L+ RTP+QVA ++
Sbjct: 580 RAAVQKRSFNVIVAIYKQIYERVHDPANGFEQPEQLLHRTPEQVAHIL 627
>sp|Q21270|COG6_CAEEL Putative conserved oligomeric Golgi complex component 6
Length = 642
Score = 62.4 bits (150), Expect = 1e-09
Identities = 50/223 (22%), Positives = 106/223 (47%), Gaps = 10/223 (4%)
Frame = +2
Query: 2 LEKIETPQHNLAPTPAIQKTLRLLEEILTAQ----DVSMLPTSSNKSDLQQVLYTLIDPL 169
+ K+ +P ++L P P +++ L L +++ D+++L + +++ +++PL
Sbjct: 394 MRKMTSPHYDLLPVPEVRQCLSLYHGLISIAVKTGDLNLL------LEPERIYEYVLEPL 447
Query: 170 LQYCCLSASSI-SPVEAAVYLCNCLYLYQTALAKFEYTDAKLEQIQGQLDANVDSLVSFQ 346
+Q LSA+ + S +E +V+ NCL + ++A+++ K+E I ++ N D LVS Q
Sbjct: 448 IQTVQLSATRLKSDIEVSVFTINCLTVIRSAISEISAFKKKIEMIDAMIEGNSDVLVSVQ 507
Query: 347 AGFVIRSSGLSVLYELVEQDN-NDNNDIVLSDRVPELSVKKIMAQFDLFL----AHPDTL 511
++ SG+ LY+ N + + + +V + + F +L + T
Sbjct: 508 VSEMLEKSGILELYQKFNAVNPAEKKPLSTLPGLESTTVGEAIVMFTQYLHNHASSDHTY 567
Query: 512 MMPQLALLSSIKLKDLIRRRSNDLVHSAYTRLFNAIRKPASGY 640
+ Q L S + + IR R+ Y + + + P +GY
Sbjct: 568 DIDQQILASEERQR--IRERNTLEFLKVYKMIVDRLGNPTNGY 608
>sp|Q7NDH1|DNAK_GLOVI Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa
protein) (HSP70)
Length = 638
Score = 30.8 bits (68), Expect = 4.2
Identities = 19/57 (33%), Positives = 31/57 (54%)
Frame = +2
Query: 50 IQKTLRLLEEILTAQDVSMLPTSSNKSDLQQVLYTLIDPLLQYCCLSASSISPVEAA 220
I+ ++ L E L+ +D+ + +S K+DLQQ +Y L L Q S ++ P E A
Sbjct: 559 IEGLIKDLREALSREDMDKV--ASLKADLQQAVYDLSSKLYQQSAPSGAAAGPDEGA 613
>sp|P51711|REP_BPHP1 Replication protein
Length = 775
Score = 30.4 bits (67), Expect = 5.5
Identities = 28/146 (19%), Positives = 65/146 (44%), Gaps = 12/146 (8%)
Frame = +2
Query: 197 SISPVEAAVYLCNCLYLYQTALAKFEYTDAKLEQIQGQLDANVDSLVSFQAGFVIRSSGL 376
++ P + + Y L L+ T FE+ + KLE + Q + +A ++ G
Sbjct: 40 TLLPFDESCYTPLQLELFATNPVDFEFIEQKLENLPRQRQREYFRKLYLKAYRSVKDDG- 98
Query: 377 SVLYELVEQDNNDNNDIVLSDRVPELSVKKIMAQFDL-------FLAHPDTLM-----MP 520
S+ + L + ND + + ++ ++K+ +Q+++ F+ P L+ M
Sbjct: 99 SIAFLLGNKQRRHANDYLRD--ILDVRLQKVFSQYNVNVDFLQAFINTPQWLLSVKDEMQ 156
Query: 521 QLALLSSIKLKDLIRRRSNDLVHSAY 598
Q S++ ++ + + N+L +S +
Sbjct: 157 QAVQFSTVPTREELAKHYNELHYSGF 182
>sp|P31069|KCH_ECOLI Putative potassium channel protein
Length = 417
Score = 29.6 bits (65), Expect = 9.3
Identities = 22/88 (25%), Positives = 43/88 (48%), Gaps = 9/88 (10%)
Frame = +2
Query: 290 LEQIQGQLDANVDSLVS-FQAGFVIRSSGLSVLYELVEQDNND--NNDIVLSDRVPELSV 460
++Q++ +L N D + V++ +G+ ++ +ND N +VLS + V
Sbjct: 280 IKQLEQRLGDNADVIPGDSNDSSVLKKAGIDRCRAILALSDNDADNAFVVLSAKDMSSDV 339
Query: 461 KKIMAQFD------LFLAHPDTLMMPQL 526
K ++A D + + HPD ++ PQL
Sbjct: 340 KTVLAVSDSKNLNKIKMVHPDIILSPQL 367
>sp|Q18297|TRPA1_CAEEL Transient receptor potential cation channel subfamily A member 1
homolog
Length = 1193
Score = 29.6 bits (65), Expect = 9.3
Identities = 16/48 (33%), Positives = 26/48 (54%)
Frame = +2
Query: 266 KFEYTDAKLEQIQGQLDANVDSLVSFQAGFVIRSSGLSVLYELVEQDN 409
K + AKL+ IQ +D + V +A ++GL++ EL E+DN
Sbjct: 1146 KLQNQAAKLKNIQENIDVMYEKQVRLEAIIAKLATGLNINIELEEKDN 1193
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 84,388,065
Number of Sequences: 369166
Number of extensions: 1651455
Number of successful extensions: 4415
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 4304
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4413
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7066925600
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)