Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_020_O12
(945 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O43772|MCAT_HUMAN Mitochondrial carnitine/acylcarnitine ... 366 e-101
sp|Q8HXY2|MCAT_MACFA Mitochondrial carnitine/acylcarnitine ... 363 e-100
sp|P97521|MCAT_RAT Mitochondrial carnitine/acylcarnitine ca... 359 7e-99
sp|Q9Z2Z6|MCAT_MOUSE Mitochondrial carnitine/acylcarnitine ... 357 2e-98
sp|Q9VQG4|COLT_DROME Congested-like trachea protein 322 1e-87
sp|Q27257|DIF1_CAEEL Protein dif-1 308 2e-83
sp|Q93XM7|MCAT_ARATH Mitochondrial carnitine/acylcarnitine ... 187 3e-47
sp|Q9WVD5|ORNT1_MOUSE Mitochondrial ornithine transporter 1... 160 6e-39
sp|Q9Y619|ORNT1_HUMAN Mitochondrial ornithine transporter 1... 158 2e-38
sp|Q12289|CRC1_YEAST Mitochondrial carnitine carrier 158 2e-38
>sp|O43772|MCAT_HUMAN Mitochondrial carnitine/acylcarnitine carrier protein
(Carnitine/acylcarnitine translocase) (CAC)
Length = 301
Score = 366 bits (939), Expect = e-101
Identities = 181/291 (62%), Positives = 213/291 (73%)
Frame = +1
Query: 10 KEIHPLKSFIAXXXXXXXXXXXXQPLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRN 189
K I PLK+ +A PLDT+KVRLQ P PG+PP+Y G DCF +TL
Sbjct: 6 KPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFR 65
Query: 190 EGPVGFYKGMAAPLIGVTPMFAVCFFGYNLGRKLQVKDENTPLTKPQIFAAGMLSGVFTT 369
EG G Y+GMAAP+IGVTPMFAVCFFG+ LG+KLQ K L+ PQ+FAAGMLSGVFTT
Sbjct: 66 EGITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDVLSYPQLFAAGMLSGVFTT 125
Query: 370 AIMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATG 549
IMTPGERIKCLLQ+Q +S E KY G D +KLY+E GIR IYKGT TL+RD+PA+G
Sbjct: 126 GIMTPGERIKCLLQIQASSGES-KYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASG 184
Query: 550 TYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGK 729
YFM+YEWLK I TPEG S LS R L AGGIAG+ NW V IPPD LKSR QTAP GK
Sbjct: 185 MYFMTYEWLKNIFTPEGKRVSELSAPRILVAGGIAGIFNWAVAIPPDVLKSRFQTAPPGK 244
Query: 730 YPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLN 882
YP+G R V RE++ +EG+ LY+G + V+IRAFPANAACFLG+EV++K LN
Sbjct: 245 YPNGFRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMKFLN 295
Score = 66.6 bits (161), Expect = 1e-10
Identities = 40/95 (42%), Positives = 52/95 (54%), Gaps = 5/95 (5%)
Frame = +1
Query: 616 LSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPE---GKYP--HGLRSVFREMMANEG 780
+SP + L AGG G+C V P DT+K RLQT P G+ P G FR+ + EG
Sbjct: 8 ISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREG 67
Query: 781 IVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLNK 885
I GLYRG++ +I P A CF G+ + KL K
Sbjct: 68 ITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQK 102
>sp|Q8HXY2|MCAT_MACFA Mitochondrial carnitine/acylcarnitine carrier protein
(Carnitine/acylcarnitine translocase) (CAC)
Length = 301
Score = 363 bits (933), Expect = e-100
Identities = 179/291 (61%), Positives = 213/291 (73%)
Frame = +1
Query: 10 KEIHPLKSFIAXXXXXXXXXXXXQPLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRN 189
K I PLK+ +A PLDT+KVRLQ P PG+PP+Y G DCF +TL
Sbjct: 6 KPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFR 65
Query: 190 EGPVGFYKGMAAPLIGVTPMFAVCFFGYNLGRKLQVKDENTPLTKPQIFAAGMLSGVFTT 369
EG G Y+GMAAP+IGVTPMFAVCFFG+ LG+KLQ K L+ PQ+FAAGMLSG+FTT
Sbjct: 66 EGIRGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDVLSYPQLFAAGMLSGIFTT 125
Query: 370 AIMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATG 549
IMTPGERIKCLLQ+Q +S E KY G D +KLY+E GIR IYKGT TL+RD+PA+G
Sbjct: 126 GIMTPGERIKCLLQIQASSGET-KYTGTLDCAKKLYQEFGIRGIYKGTVVTLMRDVPASG 184
Query: 550 TYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGK 729
YFM+YEW+K I TPEG S LS R L AGGIAG+ NW V IPPD LKSR QTAP GK
Sbjct: 185 MYFMTYEWVKNIFTPEGKRVSELSVPRVLVAGGIAGIFNWAVAIPPDVLKSRFQTAPPGK 244
Query: 730 YPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLN 882
YP+G R V RE++ +EG+ LY+G + V+IRAFPANAACFLG+EV++K LN
Sbjct: 245 YPNGFRDVLRELIPDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMKFLN 295
Score = 65.5 bits (158), Expect = 2e-10
Identities = 40/95 (42%), Positives = 52/95 (54%), Gaps = 5/95 (5%)
Frame = +1
Query: 616 LSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPE---GKYP--HGLRSVFREMMANEG 780
+SP + L AGG G+C V P DT+K RLQT P G+ P G FR+ + EG
Sbjct: 8 ISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREG 67
Query: 781 IVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLNK 885
I GLYRG++ +I P A CF G+ + KL K
Sbjct: 68 IRGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQK 102
>sp|P97521|MCAT_RAT Mitochondrial carnitine/acylcarnitine carrier protein
(Carnitine/acylcarnitine translocase) (CAC)
Length = 301
Score = 359 bits (921), Expect = 7e-99
Identities = 174/291 (59%), Positives = 209/291 (71%)
Frame = +1
Query: 10 KEIHPLKSFIAXXXXXXXXXXXXQPLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRN 189
K I PLK+ +A PLDT+KVRLQ P PG+PP+Y G +DCF +TL
Sbjct: 6 KPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTIDCFRKTLFR 65
Query: 190 EGPVGFYKGMAAPLIGVTPMFAVCFFGYNLGRKLQVKDENTPLTKPQIFAAGMLSGVFTT 369
EG G Y+GMAAP+IGVTPMFAVCFFG+ LG++LQ K LT PQ+F AGMLSGVFTT
Sbjct: 66 EGITGLYRGMAAPIIGVTPMFAVCFFGFGLGKRLQQKSPEDELTYPQLFTAGMLSGVFTT 125
Query: 370 AIMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATG 549
IMTPGERIKCLLQ+Q AS KY G D +KLY+E GIR YKGTA TL+RD+PA+G
Sbjct: 126 GIMTPGERIKCLLQIQ-ASSGKNKYSGTLDCAKKLYQEFGIRGFYKGTALTLMRDVPASG 184
Query: 550 TYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGK 729
YFM+YEWLK + TP+G LS R L AGG G+ NW+V IPPD LKSR QTAP GK
Sbjct: 185 MYFMTYEWLKNLFTPQGKSVHDLSVPRVLVAGGFRGIFNWVVAIPPDVLKSRFQTAPPGK 244
Query: 730 YPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLN 882
YP+G R V RE++ EG+ LY+G + V+IRAFPANAACFLG+E+ +K+LN
Sbjct: 245 YPNGFRDVLRELIREEGVTSLYKGFNAVMIRAFPANAACFLGFEIPMKILN 295
Score = 65.5 bits (158), Expect = 2e-10
Identities = 39/95 (41%), Positives = 52/95 (54%), Gaps = 5/95 (5%)
Frame = +1
Query: 616 LSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPE---GKYP--HGLRSVFREMMANEG 780
+SP + L AGG G+C V P DT+K RLQT P G+ P G FR+ + EG
Sbjct: 8 ISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTIDCFRKTLFREG 67
Query: 781 IVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLNK 885
I GLYRG++ +I P A CF G+ + +L K
Sbjct: 68 ITGLYRGMAAPIIGVTPMFAVCFFGFGLGKRLQQK 102
>sp|Q9Z2Z6|MCAT_MOUSE Mitochondrial carnitine/acylcarnitine carrier protein
(Carnitine/acylcarnitine translocase) (CAC) (mCAC)
Length = 301
Score = 357 bits (917), Expect = 2e-98
Identities = 174/291 (59%), Positives = 208/291 (71%)
Frame = +1
Query: 10 KEIHPLKSFIAXXXXXXXXXXXXQPLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRN 189
K I P K+ +A PLDT+KVRLQ P G+PP+Y G +DCF +TL
Sbjct: 6 KPISPFKNLLAGGFGGMCLVFVGHPLDTVKVRLQTQPPSLSGQPPMYSGTLDCFRKTLMR 65
Query: 190 EGPVGFYKGMAAPLIGVTPMFAVCFFGYNLGRKLQVKDENTPLTKPQIFAAGMLSGVFTT 369
EG G Y+GMAAP+IGVTPMFAVCFFG+ LG+KLQ K L+ PQ+F AGMLSGVFTT
Sbjct: 66 EGITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKSPEDELSYPQLFTAGMLSGVFTT 125
Query: 370 AIMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATG 549
IMTPGERIKCLLQ+Q +S E KY G D +KLY+E GIR YKGT TL+RD+PA+G
Sbjct: 126 GIMTPGERIKCLLQIQASSGEN-KYSGTLDCAKKLYQEFGIRGFYKGTVLTLMRDVPASG 184
Query: 550 TYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGK 729
YFM+YEWLK + TPEG S LS R L AGG AG+ NW V IPPD LKSR QTAP GK
Sbjct: 185 MYFMTYEWLKNLFTPEGKSVSDLSVPRILVAGGFAGIFNWAVAIPPDVLKSRFQTAPPGK 244
Query: 730 YPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLN 882
YP+G R V RE++ EG+ LY+G + V+IRAFPANAACFLG+E+++K LN
Sbjct: 245 YPNGFRDVLRELIREEGVTSLYKGFNAVMIRAFPANAACFLGFEIAMKFLN 295
Score = 69.7 bits (169), Expect = 1e-11
Identities = 41/95 (43%), Positives = 52/95 (54%), Gaps = 5/95 (5%)
Frame = +1
Query: 616 LSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAP---EGKYP--HGLRSVFREMMANEG 780
+SP + L AGG GMC V P DT+K RLQT P G+ P G FR+ + EG
Sbjct: 8 ISPFKNLLAGGFGGMCLVFVGHPLDTVKVRLQTQPPSLSGQPPMYSGTLDCFRKTLMREG 67
Query: 781 IVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLNK 885
I GLYRG++ +I P A CF G+ + KL K
Sbjct: 68 ITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQK 102
>sp|Q9VQG4|COLT_DROME Congested-like trachea protein
Length = 306
Score = 322 bits (825), Expect = 1e-87
Identities = 154/295 (52%), Positives = 206/295 (69%)
Frame = +1
Query: 4 THKEIHPLKSFIAXXXXXXXXXXXXQPLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTL 183
T ++ +P+KSF+ PLDT+KVRLQ MP P PGE P+Y+G DC +T+
Sbjct: 9 TERKANPVKSFLTGGFGGICNVLSGHPLDTIKVRLQTMPRPAPGEQPLYRGTFDCAAKTI 68
Query: 184 RNEGPVGFYKGMAAPLIGVTPMFAVCFFGYNLGRKLQVKDENTPLTKPQIFAAGMLSGVF 363
+NEG G YKGM+APL GV P+FA+CF GY LG++LQ + E+ LT PQIF AG SG+F
Sbjct: 69 KNEGVRGLYKGMSAPLTGVAPIFAMCFAGYALGKRLQQRGEDAKLTYPQIFVAGSFSGLF 128
Query: 364 TTAIMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPA 543
+T IM PGERIK LLQ Q KY G D KLYKEGG+RS++KG+ AT+LRD+PA
Sbjct: 129 STLIMAPGERIKVLLQTQQGQGGERKYNGMIDCAGKLYKEGGLRSVFKGSCATMLRDLPA 188
Query: 544 TGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPE 723
G YF+ YE L+++ + + +S T+FAGG+AGM W++ +P D LKSRLQ+APE
Sbjct: 189 NGLYFLVYEALQDVAKSK-SETGQISTASTIFAGGVAGMAYWILGMPADVLKSRLQSAPE 247
Query: 724 GKYPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLNKV 888
G Y HG+RSVF++++ +G + LYRGV+P+++RAFPANAACF G E++ K N V
Sbjct: 248 GTYKHGIRSVFKDLIVKDGPLALYRGVTPIMLRAFPANAACFFGIELANKFFNIV 302
>sp|Q27257|DIF1_CAEEL Protein dif-1
Length = 312
Score = 308 bits (788), Expect = 2e-83
Identities = 158/284 (55%), Positives = 198/284 (69%), Gaps = 2/284 (0%)
Frame = +1
Query: 25 LKSFIAXXXXXXXXXXXXQPLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVG 204
L +FIA P DT+KVR+Q MP+PKPGE P + G +DC +T+ EG
Sbjct: 5 LLNFIAGGVGGSCTVIVGHPFDTVKVRIQTMPMPKPGEKPQFTGALDCVKRTVSKEGFFA 64
Query: 205 FYKGMAAPLIGVTPMFAVCFFGYNLGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTP 384
YKGMAAPL+GV+P+FAV F G +G+ LQ D + +T Q AG L+GVFTT +M P
Sbjct: 65 LYKGMAAPLVGVSPLFAVFFGGCAVGKWLQQTDPSQEMTFIQNANAGALAGVFTTIVMVP 124
Query: 385 GERIKCLLQVQ--GASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYF 558
GERIKCLLQVQ G++ Y GP DV++KLYK+GGI SIY+GT ATLLRDIPA+ Y
Sbjct: 125 GERIKCLLQVQQAGSAGSGVHYDGPLDVVKKLYKQGGISSIYRGTGATLLRDIPASAAYL 184
Query: 559 MSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPH 738
YE+LK+ + EG ++ LSPG TL AGG+AG+ NW VCIP D LKSRLQTAPEGKYP
Sbjct: 185 SVYEYLKKKFSGEGAQRT-LSPGATLMAGGLAGIANWGVCIPADVLKSRLQTAPEGKYPD 243
Query: 739 GLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYEVSL 870
G+R V RE++ EG L++G PV++RAFPANAACF G E++L
Sbjct: 244 GIRGVLREVLREEGPRALFKGFWPVMLRAFPANAACFFGLELTL 287
>sp|Q93XM7|MCAT_ARATH Mitochondrial carnitine/acylcarnitine carrier-like protein (A BOUT
DE SOUFFLE) (Carnitine/acylcarnitine translocase-like
protein) (CAC-like protein)
Length = 300
Score = 187 bits (476), Expect = 3e-47
Identities = 113/274 (41%), Positives = 144/274 (52%), Gaps = 12/274 (4%)
Frame = +1
Query: 82 PLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAVC 261
P DT+KV+LQ+ P P PG+ P Y G +D QT+ +EG G YKGM APL V AV
Sbjct: 24 PFDTIKVKLQSQPTPAPGQLPRYTGAIDAVKQTVASEGTKGLYKGMGAPLATVAAFNAVL 83
Query: 262 FFGYNLGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQGASK---- 429
F L + PLT Q F AG +G + + P E IKC LQ QGA
Sbjct: 84 FTVRGQMEGLLRSEAGVPLTISQQFVAGAGAGFAVSFLACPTELIKCRLQAQGALAGAST 143
Query: 430 -----EPPKYKGPGDVIRK-LYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILT 591
KY GP DV R L EGG R ++KG T R++P T F +YE K L
Sbjct: 144 TSSVVAAVKYGGPMDVARHVLRSEGGARGLFKGLFPTFAREVPGNATMFAAYEAFKRFLA 203
Query: 592 PEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPH--GLRSVFREM 765
G D S L G + AGG+AG W + P D +KS LQ + K P G FR++
Sbjct: 204 -GGSDTSSLGQGSLIMAGGVAGASFWGIVYPTDVVKSVLQ-VDDYKNPRYTGSMDAFRKI 261
Query: 766 MANEGIVGLYRGVSPVLIRAFPANAACFLGYEVS 867
+ +EG+ GLY+G P + R+ PANAACFL YE++
Sbjct: 262 LKSEGVKGLYKGFGPAMARSVPANAACFLAYEMT 295
Score = 67.0 bits (162), Expect = 7e-11
Identities = 43/149 (28%), Positives = 68/149 (45%), Gaps = 2/149 (1%)
Frame = +1
Query: 148 YKGLVDCFLQTLRNEGPV-GFYKGMAAPLIGVTPMFAVCFFGYNLGRKLQVKDENTP-LT 321
Y G +D LR+EG G +KG+ P A F Y ++ +T L
Sbjct: 153 YGGPMDVARHVLRSEGGARGLFKGLFPTFAREVPGNATMFAAYEAFKRFLAGGSDTSSLG 212
Query: 322 KPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLYKEGGIRSI 501
+ + AG ++G I+ P + +K +LQV P+Y G D RK+ K G++ +
Sbjct: 213 QGSLIMAGGVAGASFWGIVYPTDVVKSVLQVDDYKN--PRYTGSMDAFRKILKSEGVKGL 270
Query: 502 YKGTAATLLRDIPATGTYFMSYEWLKEIL 588
YKG + R +PA F++YE + L
Sbjct: 271 YKGFGPAMARSVPANAACFLAYEMTRSSL 299
Score = 58.2 bits (139), Expect = 3e-08
Identities = 53/197 (26%), Positives = 79/197 (40%), Gaps = 16/197 (8%)
Frame = +1
Query: 337 AAGMLSGVFTTAIMTPGERIKCLLQVQG--ASKEPPKYKGPGDVIRKLYKEGGIRSIYKG 510
A+G + G + P + IK LQ Q A + P+Y G D +++ G + +YKG
Sbjct: 9 ASGTVGGAAQLVVGHPFDTIKVKLQSQPTPAPGQLPRYTGAIDAVKQTVASEGTKGLYKG 68
Query: 511 TAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPD 690
A L F ++ +L E G +S + AG AG + P +
Sbjct: 69 MGAPLATVAAFNAVLFTVRGQMEGLLRSEAGVPLTIS--QQFVAGAGAGFAVSFLACPTE 126
Query: 691 TLKSRLQT-------------APEGKYPHGLRSVFREMMANEGIV-GLYRGVSPVLIRAF 828
+K RLQ KY G V R ++ +EG GL++G+ P R
Sbjct: 127 LIKCRLQAQGALAGASTTSSVVAAVKYG-GPMDVARHVLRSEGGARGLFKGLFPTFAREV 185
Query: 829 PANAACFLGYEVSLKLL 879
P NA F YE + L
Sbjct: 186 PGNATMFAAYEAFKRFL 202
Score = 40.8 bits (94), Expect = 0.006
Identities = 23/68 (33%), Positives = 30/68 (44%)
Frame = +1
Query: 82 PLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAVC 261
P D +K LQ P Y G +D F + L++EG G YKG + P A C
Sbjct: 233 PTDVVKSVLQVDDYKNPR----YTGSMDAFRKILKSEGVKGLYKGFGPAMARSVPANAAC 288
Query: 262 FFGYNLGR 285
F Y + R
Sbjct: 289 FLAYEMTR 296
>sp|Q9WVD5|ORNT1_MOUSE Mitochondrial ornithine transporter 1 (Solute carrier family 25
member 15)
Length = 301
Score = 160 bits (404), Expect = 6e-39
Identities = 97/275 (35%), Positives = 138/275 (50%), Gaps = 8/275 (2%)
Frame = +1
Query: 79 QPLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAV 258
QP DT+KV++Q P +Y+GL DC L+T G GFYKG + LI +V
Sbjct: 28 QPFDTMKVKMQTFP-------DLYRGLTDCCLKTYSQVGFRGFYKGTSPALIANIAENSV 80
Query: 259 CFFGYN----LGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQ----V 414
F Y + RK+ D+ L+ Q AAG + F ++ P E +KC LQ +
Sbjct: 81 LFMCYGFCQQVVRKVVGLDQQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRLQTMYEM 140
Query: 415 QGASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTP 594
+ + K V+++++++ G Y G ++TLLR++P +F YE L
Sbjct: 141 ETSGKIAASQNTVWSVVKEIFRKDGPLGFYHGLSSTLLREVPGYFFFFGGYE-LSRSFFA 199
Query: 595 EGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMAN 774
G K L P + +GG G+C WL P D +KSR+Q GL F ++ N
Sbjct: 200 SGRSKDELGPVPLMLSGGFGGICLWLAVYPVDCIKSRIQVLSMTGKQTGLVRTFLSIVKN 259
Query: 775 EGIVGLYRGVSPVLIRAFPANAACFLGYEVSLKLL 879
EGI LY G+ P +IRAFPAN A FL YE S KL+
Sbjct: 260 EGITALYSGLKPTMIRAFPANGALFLAYEYSRKLM 294
Score = 41.2 bits (95), Expect = 0.004
Identities = 27/85 (31%), Positives = 39/85 (45%)
Frame = +1
Query: 634 LFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPV 813
L AG G L P DT+K ++QT P+ GL + + G G Y+G SP
Sbjct: 13 LTAGAAGGTACVLTGQPFDTMKVKMQTFPD--LYRGLTDCCLKTYSQVGFRGFYKGTSPA 70
Query: 814 LIRAFPANAACFLGYEVSLKLLNKV 888
LI N+ F+ Y +++ KV
Sbjct: 71 LIANIAENSVLFMCYGFCQQVVRKV 95
Score = 39.3 bits (90), Expect = 0.016
Identities = 22/72 (30%), Positives = 32/72 (44%)
Frame = +1
Query: 82 PLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAVC 261
P+D +K R+Q + + GLV FL ++NEG Y G+ +I P
Sbjct: 229 PVDCIKSRIQVLSMTGK-----QTGLVRTFLSIVKNEGITALYSGLKPTMIRAFPANGAL 283
Query: 262 FFGYNLGRKLQV 297
F Y RKL +
Sbjct: 284 FLAYEYSRKLMM 295
>sp|Q9Y619|ORNT1_HUMAN Mitochondrial ornithine transporter 1 (Solute carrier family 25,
member 15)
Length = 301
Score = 158 bits (400), Expect = 2e-38
Identities = 97/275 (35%), Positives = 136/275 (49%), Gaps = 8/275 (2%)
Frame = +1
Query: 79 QPLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAV 258
QP DT+KV++Q P +Y+GL DC L+T G GFYKG + LI +V
Sbjct: 28 QPFDTMKVKMQTFP-------DLYRGLTDCCLKTYSQVGFRGFYKGTSPALIANIAENSV 80
Query: 259 CFFGYN----LGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQ----V 414
F Y + RK+ D+ L+ Q AAG + F ++ P E +KC LQ +
Sbjct: 81 LFMCYGFCQQVVRKVAGLDKQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRLQTMYEM 140
Query: 415 QGASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTP 594
+ + K VI+ + ++ G Y G ++TLLR++P +F YE L
Sbjct: 141 ETSGKIAKSQNTVWSVIKSILRKDGPLGFYHGLSSTLLREVPGYFFFFGGYE-LSRSFFA 199
Query: 595 EGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMAN 774
G K L P + +GG+ G+C WL P D +KSR+Q G F ++ N
Sbjct: 200 SGRSKDELGPVPLMLSGGVGGICLWLAVYPVDCIKSRIQVLSMSGKQAGFIRTFINVVKN 259
Query: 775 EGIVGLYRGVSPVLIRAFPANAACFLGYEVSLKLL 879
EGI LY G+ P +IRAFPAN A FL YE S KL+
Sbjct: 260 EGITALYSGLKPTMIRAFPANGALFLAYEYSRKLM 294
Score = 41.2 bits (95), Expect = 0.004
Identities = 27/85 (31%), Positives = 39/85 (45%)
Frame = +1
Query: 634 LFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPV 813
L AG G L P DT+K ++QT P+ GL + + G G Y+G SP
Sbjct: 13 LTAGAAGGTACVLTGQPFDTMKVKMQTFPD--LYRGLTDCCLKTYSQVGFRGFYKGTSPA 70
Query: 814 LIRAFPANAACFLGYEVSLKLLNKV 888
LI N+ F+ Y +++ KV
Sbjct: 71 LIANIAENSVLFMCYGFCQQVVRKV 95
Score = 37.0 bits (84), Expect = 0.081
Identities = 19/72 (26%), Positives = 31/72 (43%)
Frame = +1
Query: 82 PLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAVC 261
P+D +K R+Q + + G + F+ ++NEG Y G+ +I P
Sbjct: 229 PVDCIKSRIQVLSMSGK-----QAGFIRTFINVVKNEGITALYSGLKPTMIRAFPANGAL 283
Query: 262 FFGYNLGRKLQV 297
F Y RKL +
Sbjct: 284 FLAYEYSRKLMM 295
>sp|Q12289|CRC1_YEAST Mitochondrial carnitine carrier
Length = 327
Score = 158 bits (400), Expect = 2e-38
Identities = 108/300 (36%), Positives = 151/300 (50%), Gaps = 13/300 (4%)
Frame = +1
Query: 25 LKSFIAXXXXXXXXXXXXQPLDTLKVRLQAMPIPKPGEP--PVYKGLVDCFLQTLRNEGP 198
+KSF+A P D +KVR Q + K TL
Sbjct: 36 IKSFVAGGVGGVCAVFTGHPFDLIKVRCQNGQANSTVHAITNIIKEAKTQVKGTLFTNSV 95
Query: 199 VGFYKGMAAPLIGVTPMFAVCFFGYNLGRKL----QVKDENTPLTKPQIFAAGMLSGVFT 366
GFYKG+ PL+GVTP+FAV F+GY++G+KL + + LT Q+ AAG +S + T
Sbjct: 96 KGFYKGVIPPLLGVTPIFAVSFWGYDVGKKLVTFNNKQGGSNELTMGQMAAAGFISAIPT 155
Query: 367 TAIMTPGERIKCLLQVQGASKEPPKYKGPG-DVIRKLYKEGGIRSIYKGTAATLLRDIPA 543
T + P ER+K +LQ KG + + KEGGI S++KG+ ATL RD P
Sbjct: 156 TLVTAPTERVKVVLQTSS--------KGSFIQAAKTIVKEGGIASLFKGSLATLARDGPG 207
Query: 544 TGTYFMSYEWLKEILT-----PEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRL 708
+ YF SYE K L + G ++ AGGIAGM WL P DT+K++L
Sbjct: 208 SALYFASYEISKNYLNSRQPRQDAGKDEPVNILNVCLAGGIAGMSMWLAVFPIDTIKTKL 267
Query: 709 QTAPEGKYPHGLRSVFREM-MANEGIVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLNK 885
Q + + + S +E+ + GI G + G+ P L+R+FPANAA FLG E++ L K
Sbjct: 268 QASSTRQ---NMLSATKEIYLQRGGIKGFFPGLGPALLRSFPANAATFLGVEMTHSLFKK 324
Score = 37.4 bits (85), Expect = 0.062
Identities = 34/151 (22%), Positives = 59/151 (39%), Gaps = 9/151 (5%)
Frame = +1
Query: 175 QTLRNEGPVG-FYKGMAAPLIGVTPMFAVCFFGYNLGRKL-------QVKDENTPLTKPQ 330
+T+ EG + +KG A L P A+ F Y + + Q ++ P+
Sbjct: 182 KTIVKEGGIASLFKGSLATLARDGPGSALYFASYEISKNYLNSRQPRQDAGKDEPVNILN 241
Query: 331 IFAAGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLY-KEGGIRSIYK 507
+ AG ++G+ + P + IK LQ + +++Y + GGI+ +
Sbjct: 242 VCLAGGIAGMSMWLAVFPIDTIKTKLQASSTRQNMLS------ATKEIYLQRGGIKGFFP 295
Query: 508 GTAATLLRDIPATGTYFMSYEWLKEILTPEG 600
G LLR PA F+ E + G
Sbjct: 296 GLGPALLRSFPANAATFLGVEMTHSLFKKYG 326
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 114,611,903
Number of Sequences: 369166
Number of extensions: 2595200
Number of successful extensions: 7453
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6233
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6748
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9798962520
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)