Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_020_N18
(803 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q61166|MARE1_MOUSE Microtubule-associated protein RP/EB ... 237 2e-62
sp|Q66HR2|MARE1_RAT Microtubule-associated protein RP/EB fa... 235 1e-61
sp|Q6PER3|MARE3_MOUSE Microtubule-associated protein RP/EB ... 233 4e-61
sp|Q9UPY8|MARE3_HUMAN Microtubule-associated protein RP/EB ... 232 8e-61
sp|Q3ZBD9|MARE1_BOVIN Microtubule-associated protein RP/EB ... 231 1e-60
sp|Q5R7Z5|MARE1_PONPY Microtubule-associated protein RP/EB ... 229 5e-60
sp|Q15691|MARE1_HUMAN Microtubule-associated protein RP/EB ... 229 7e-60
sp|Q5ZLC7|MARE1_CHICK Microtubule-associated protein RP/EB ... 228 2e-59
sp|Q6P848|MARE1_XENTR Microtubule-associated protein RP/EB ... 228 2e-59
sp|Q6V291|MARE1_COTCO Microtubule-associated protein RP/EB ... 226 4e-59
>sp|Q61166|MARE1_MOUSE Microtubule-associated protein RP/EB family member 1 (APC-binding
protein EB1) (End-binding protein 1) (EB1)
Length = 268
Score = 237 bits (605), Expect = 2e-62
Identities = 133/257 (51%), Positives = 170/257 (66%), Gaps = 2/257 (0%)
Frame = +1
Query: 37 AVNVYSTNQTSDNVSRNDIIAWINGCLDVNVGKIEELCNGALYCHLMDMLFPGTLQFKKI 216
AVNVYST+ TSDN+SR+D++AWIN L +N+ KIE+LC+GA YC MDMLFPG++ KK+
Sbjct: 2 AVNVYSTSVTSDNLSRHDMLAWINESLQLNLTKIEQLCSGAAYCQFMDMLFPGSIALKKV 61
Query: 217 KFNTNLEHEYINNFKVLQSLFKKHGVDKEAPVSKLVKGKFQDNFEFVQWFKRFFDANYDG 396
KF LEHEYI NFK+LQ+ FK+ GVDK PV KLVKGKFQDNFEFVQWFK+FFDANYDG
Sbjct: 62 KFQAKLEHEYIQNFKILQAGFKRMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYDG 121
Query: 397 HEYDPLAARGGEIVQGTGRNAVKPSGDSLQRPNYSAPRR--ASATNAITKPTAVKQSTAP 570
EYDP+AAR G+ AV P SL P S P++ S+T A +P A +++TA
Sbjct: 122 KEYDPVAARQGQ------ETAVAP---SLVAPALSKPKKPLGSSTAAPQRPIATQRTTA- 171
Query: 571 KPAMIRPSAQPTQQSKVSPAGSHNSVTINGGDQAEVGKLRKAIESLTLQSEDDKTTIDNL 750
P A P K G NG D+A +L + ++ L K T+++L
Sbjct: 172 -----APKAGPGMVRKNPGVG-------NGDDEA--AELMQQVKVL-------KLTVEDL 210
Query: 751 MRERDFYFNKLRDIEVL 801
+ERDFYF KLR+IE++
Sbjct: 211 EKERDFYFGKLRNIELI 227
>sp|Q66HR2|MARE1_RAT Microtubule-associated protein RP/EB family member 1 (APC-binding
protein EB1) (End-binding protein 1) (EB1)
Length = 268
Score = 235 bits (599), Expect = 1e-61
Identities = 132/257 (51%), Positives = 169/257 (65%), Gaps = 2/257 (0%)
Frame = +1
Query: 37 AVNVYSTNQTSDNVSRNDIIAWINGCLDVNVGKIEELCNGALYCHLMDMLFPGTLQFKKI 216
AVNVYST+ TSDN+SR+D++AWIN L +N+ KIE+LC+GA YC MDMLFPG++ KK+
Sbjct: 2 AVNVYSTSVTSDNLSRHDMLAWINESLQLNLTKIEQLCSGAAYCQFMDMLFPGSIALKKV 61
Query: 217 KFNTNLEHEYINNFKVLQSLFKKHGVDKEAPVSKLVKGKFQDNFEFVQWFKRFFDANYDG 396
KF LEHEYI NFK+LQ+ FK+ GVDK PV KLVKGKFQDNFEFVQWFK+FFDANYDG
Sbjct: 62 KFQAKLEHEYIQNFKILQAGFKRMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYDG 121
Query: 397 HEYDPLAARGGEIVQGTGRNAVKPSGDSLQRPNYSAPRR--ASATNAITKPTAVKQSTAP 570
EYDP+AAR G+ AV P SL P S P++ S + A +P A +++TA
Sbjct: 122 KEYDPVAARQGQ------ETAVAP---SLVAPALSKPKKPLGSGSAAPQRPIATQRTTA- 171
Query: 571 KPAMIRPSAQPTQQSKVSPAGSHNSVTINGGDQAEVGKLRKAIESLTLQSEDDKTTIDNL 750
P A P K G NG D+A +L + ++ L K T+++L
Sbjct: 172 -----APKAGPGMVRKNPGMG-------NGDDEA--AELMQQVKVL-------KLTVEDL 210
Query: 751 MRERDFYFNKLRDIEVL 801
+ERDFYF KLR+IE++
Sbjct: 211 EKERDFYFGKLRNIELI 227
>sp|Q6PER3|MARE3_MOUSE Microtubule-associated protein RP/EB family member 3 (End-binding
protein 3) (EB3) (EB1 protein family member 3) (EBF3)
(RP3)
sp|Q5XIT1|MARE3_RAT Microtubule-associated protein RP/EB family member 3 (End-binding
protein 3) (EB3) (EB1 protein family member 3) (EBF3)
(RP3)
Length = 281
Score = 233 bits (595), Expect = 4e-61
Identities = 126/258 (48%), Positives = 162/258 (62%), Gaps = 3/258 (1%)
Frame = +1
Query: 37 AVNVYSTNQTSDNVSRNDIIAWINGCLDVNVGKIEELCNGALYCHLMDMLFPGTLQFKKI 216
AVNVYST+ TS+N+SR+D++AW+N L +N KIE+LC+GA YC MDMLFPG + +K+
Sbjct: 2 AVNVYSTSVTSENLSRHDMLAWVNDSLHLNYTKIEQLCSGAAYCQFMDMLFPGCVHLRKV 61
Query: 217 KFNTNLEHEYINNFKVLQSLFKKHGVDKEAPVSKLVKGKFQDNFEFVQWFKRFFDANYDG 396
KF LEHEYI+NFKVLQ+ FKK GVDK PV KLVKGKFQDNFEF+QWFK+FFDANYDG
Sbjct: 62 KFQAKLEHEYIHNFKVLQAAFKKMGVDKIIPVEKLVKGKFQDNFEFIQWFKKFFDANYDG 121
Query: 397 HEYDPLAARGGEIVQGTGRNAVKPSGDSLQRPNYSAPRRASATNAITKPTAVKQSTAPKP 576
+Y+PL AR G+ V + S + + P+R S T T+ + S P
Sbjct: 122 KDYNPLLARQGQDVAPPPNPGDQIFNKSKKLIGTAVPQRTSPTGPKNMQTSGRLSNVAPP 181
Query: 577 AMIR---PSAQPTQQSKVSPAGSHNSVTINGGDQAEVGKLRKAIESLTLQSEDDKTTIDN 747
++R PSA+ NGG +A+ I L Q D K T+D
Sbjct: 182 CILRKNPPSAR------------------NGGHEADA-----QILELNQQLLDLKLTVDG 218
Query: 748 LMRERDFYFNKLRDIEVL 801
L +ERDFYF+KLRDIE++
Sbjct: 219 LEKERDFYFSKLRDIELI 236
>sp|Q9UPY8|MARE3_HUMAN Microtubule-associated protein RP/EB family member 3 (End-binding
protein 3) (EB3) (EB1 protein family member 3) (EBF3)
(RP3)
Length = 281
Score = 232 bits (592), Expect = 8e-61
Identities = 125/258 (48%), Positives = 161/258 (62%), Gaps = 3/258 (1%)
Frame = +1
Query: 37 AVNVYSTNQTSDNVSRNDIIAWINGCLDVNVGKIEELCNGALYCHLMDMLFPGTLQFKKI 216
AVNVYST+ TS+N+SR+D++AW+N L +N KIE+LC+GA YC MDMLFPG + +K+
Sbjct: 2 AVNVYSTSVTSENLSRHDMLAWVNDSLHLNYTKIEQLCSGAAYCQFMDMLFPGCVHLRKV 61
Query: 217 KFNTNLEHEYINNFKVLQSLFKKHGVDKEAPVSKLVKGKFQDNFEFVQWFKRFFDANYDG 396
KF LEHEYI+NFKVLQ+ FKK GVDK PV KLVKGKFQDNFEF+QWFK+FFDANYDG
Sbjct: 62 KFQAKLEHEYIHNFKVLQAAFKKMGVDKIIPVEKLVKGKFQDNFEFIQWFKKFFDANYDG 121
Query: 397 HEYDPLAARGGEIVQGTGRNAVKPSGDSLQRPNYSAPRRASATNAITKPTAVKQSTAPKP 576
+Y+PL AR G+ V + S + + P+R S T T+ + S P
Sbjct: 122 KDYNPLLARQGQDVAPPPNPGDQIFNKSKKLIGTAVPQRTSPTGPKNMQTSGRLSNVAPP 181
Query: 577 AMIR---PSAQPTQQSKVSPAGSHNSVTINGGDQAEVGKLRKAIESLTLQSEDDKTTIDN 747
++R PSA+ NGG + + I L Q D K T+D
Sbjct: 182 CILRKNPPSAR------------------NGGHETDA-----QILELNQQLVDLKLTVDG 218
Query: 748 LMRERDFYFNKLRDIEVL 801
L +ERDFYF+KLRDIE++
Sbjct: 219 LEKERDFYFSKLRDIELI 236
>sp|Q3ZBD9|MARE1_BOVIN Microtubule-associated protein RP/EB family member 1 (APC-binding
protein EB1) (End-binding protein 1) (EB1)
Length = 268
Score = 231 bits (590), Expect = 1e-60
Identities = 123/255 (48%), Positives = 161/255 (63%)
Frame = +1
Query: 37 AVNVYSTNQTSDNVSRNDIIAWINGCLDVNVGKIEELCNGALYCHLMDMLFPGTLQFKKI 216
AVNVYST+ TSDN+SR+D++AWIN L +N+ KIE+LC+GA YC MDMLFPG++ KK+
Sbjct: 2 AVNVYSTSVTSDNLSRHDMLAWINESLQLNLTKIEQLCSGAAYCQFMDMLFPGSIALKKV 61
Query: 217 KFNTNLEHEYINNFKVLQSLFKKHGVDKEAPVSKLVKGKFQDNFEFVQWFKRFFDANYDG 396
KF LEHEYI NFK+LQ+ FK+ GVDK PV KLVKGKFQDNFEFVQWFK+FFDANYDG
Sbjct: 62 KFQAKLEHEYIQNFKILQAGFKRMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYDG 121
Query: 397 HEYDPLAARGGEIVQGTGRNAVKPSGDSLQRPNYSAPRRASATNAITKPTAVKQSTAPKP 576
EYDP+AAR G+ ++ P+ AP A+ KP S++ P
Sbjct: 122 KEYDPVAARQGQ--------------ETAMAPSLVAP-------ALNKPKKPLSSSSAAP 160
Query: 577 AMIRPSAQPTQQSKVSPAGSHNSVTINGGDQAEVGKLRKAIESLTLQSEDDKTTIDNLMR 756
+ + T K P + + GD E +L + + L K T+++L +
Sbjct: 161 QRPITTHRTTATPKAGPGVVRKNPGVGNGDD-EAAELMQQVNVL-------KLTVEDLEK 212
Query: 757 ERDFYFNKLRDIEVL 801
ERDFYF KLR+IE++
Sbjct: 213 ERDFYFGKLRNIELI 227
>sp|Q5R7Z5|MARE1_PONPY Microtubule-associated protein RP/EB family member 1 (APC-binding
protein EB1) (End-binding protein 1) (EB1)
Length = 268
Score = 229 bits (585), Expect = 5e-60
Identities = 126/256 (49%), Positives = 164/256 (64%), Gaps = 1/256 (0%)
Frame = +1
Query: 37 AVNVYSTNQTSDNVSRNDIIAWINGCLDVNVGKIEELCNGALYCHLMDMLFPGTLQFKKI 216
AVNVYST+ TSDN+SR+D++AWIN L +N+ KIE+LC+GA YC MDMLFPG++ KK+
Sbjct: 2 AVNVYSTSVTSDNLSRHDMLAWINESLQLNLTKIEQLCSGAAYCQFMDMLFPGSIALKKV 61
Query: 217 KFNTNLEHEYINNFKVLQSLFKKHGVDKEAPVSKLVKGKFQDNFEFVQWFKRFFDANYDG 396
KF LEHEYI NFK+LQ+ FK+ GVDK PV KLVKGKFQDNFEFVQWFK+FFDANYDG
Sbjct: 62 KFQAKLEHEYIQNFKILQAGFKRMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYDG 121
Query: 397 HEYDPLAARGGEIVQGTGRNAVKPSGDSLQRPNYSAPRR-ASATNAITKPTAVKQSTAPK 573
+YDP+AAR G+ AV P SL P + P++ S+++A + Q TA
Sbjct: 122 KDYDPVAARQGQ------ETAVAP---SLVAPALNKPKKPLSSSSAAPQRPISTQRTAAA 172
Query: 574 PAMIRPSAQPTQQSKVSPAGSHNSVTINGGDQAEVGKLRKAIESLTLQSEDDKTTIDNLM 753
P K P + + GD E +L + + L K T+++L
Sbjct: 173 P-------------KAGPGVVRKNPGVGNGDD-EAAELMQQVNVL-------KLTVEDLE 211
Query: 754 RERDFYFNKLRDIEVL 801
+ERDFYF KLR+IE++
Sbjct: 212 KERDFYFGKLRNIELI 227
>sp|Q15691|MARE1_HUMAN Microtubule-associated protein RP/EB family member 1 (APC-binding
protein EB1) (End-binding protein 1) (EB1)
Length = 268
Score = 229 bits (584), Expect = 7e-60
Identities = 128/257 (49%), Positives = 168/257 (65%), Gaps = 2/257 (0%)
Frame = +1
Query: 37 AVNVYSTNQTSDNVSRNDIIAWINGCLDVNVGKIEELCNGALYCHLMDMLFPGTLQFKKI 216
AVNVYST+ TSDN+SR+D++AWIN L +N+ KIE+LC+GA YC MDMLFPG++ KK+
Sbjct: 2 AVNVYSTSVTSDNLSRHDMLAWINESLQLNLTKIEQLCSGAAYCQFMDMLFPGSIALKKV 61
Query: 217 KFNTNLEHEYINNFKVLQSLFKKHGVDKEAPVSKLVKGKFQDNFEFVQWFKRFFDANYDG 396
KF LEHEYI NFK+LQ+ FK+ GVDK PV KLVKGKFQDNFEFVQWFK+FFDANYDG
Sbjct: 62 KFQAKLEHEYIQNFKILQAGFKRMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYDG 121
Query: 397 HEYDPLAARGGEIVQGTGRNAVKPSGDSLQRPNYSAPRR--ASATNAITKPTAVKQSTAP 570
+YDP+AAR G+ AV P SL P + P++ S++ A +P + +++ A
Sbjct: 122 KDYDPVAARQGQ------ETAVAP---SLVAPALNKPKKPLTSSSAAPQRPISTQRTAA- 171
Query: 571 KPAMIRPSAQPTQQSKVSPAGSHNSVTINGGDQAEVGKLRKAIESLTLQSEDDKTTIDNL 750
P A P K G NG D+A +L + + L K T+++L
Sbjct: 172 -----APKAGPGVVRKNPGVG-------NGDDEA--AELMQQVNVL-------KLTVEDL 210
Query: 751 MRERDFYFNKLRDIEVL 801
+ERDFYF KLR+IE++
Sbjct: 211 EKERDFYFGKLRNIELI 227
>sp|Q5ZLC7|MARE1_CHICK Microtubule-associated protein RP/EB family member 1
Length = 258
Score = 228 bits (580), Expect = 2e-59
Identities = 126/255 (49%), Positives = 159/255 (62%)
Frame = +1
Query: 37 AVNVYSTNQTSDNVSRNDIIAWINGCLDVNVGKIEELCNGALYCHLMDMLFPGTLQFKKI 216
AVNVYST+ TSDN+SR+D++AWIN L + + KIE+LC+GA YC MDMLFPG++ KK+
Sbjct: 2 AVNVYSTSVTSDNLSRHDMLAWINESLQLTLTKIEQLCSGAAYCQFMDMLFPGSVALKKV 61
Query: 217 KFNTNLEHEYINNFKVLQSLFKKHGVDKEAPVSKLVKGKFQDNFEFVQWFKRFFDANYDG 396
KF LEHEYI NFKVLQ+ FK+ GVDK PV KLVKGKFQDNFEFVQWFK+FFDANYDG
Sbjct: 62 KFQAKLEHEYIQNFKVLQAGFKRMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYDG 121
Query: 397 HEYDPLAARGGEIVQGTGRNAVKPSGDSLQRPNYSAPRRASATNAITKPTAVKQSTAPKP 576
EYDP+AAR G PN AP + KP K+ AP+
Sbjct: 122 KEYDPVAAR---------------QGQETVAPNLVAP-------VVNKP---KKPLAPQR 156
Query: 577 AMIRPSAQPTQQSKVSPAGSHNSVTINGGDQAEVGKLRKAIESLTLQSEDDKTTIDNLMR 756
++ Q++ +P GS V GD G IE + + K T+++L +
Sbjct: 157 PIV------AQRTPATPKGSTGMVKKAAGDDESAG----LIEQINVL----KLTVEDLEK 202
Query: 757 ERDFYFNKLRDIEVL 801
ERDFYF KLR+IE++
Sbjct: 203 ERDFYFGKLRNIELI 217
>sp|Q6P848|MARE1_XENTR Microtubule-associated protein RP/EB family member 1
Length = 269
Score = 228 bits (580), Expect = 2e-59
Identities = 125/255 (49%), Positives = 158/255 (61%)
Frame = +1
Query: 37 AVNVYSTNQTSDNVSRNDIIAWINGCLDVNVGKIEELCNGALYCHLMDMLFPGTLQFKKI 216
AVNVYST+ TSDN+SR+D++AWIN L +N+ KIE+LC+G++YC MDMLFPG++ KK+
Sbjct: 2 AVNVYSTSVTSDNLSRHDMLAWINESLQLNLTKIEQLCSGSVYCQFMDMLFPGSVVLKKV 61
Query: 217 KFNTNLEHEYINNFKVLQSLFKKHGVDKEAPVSKLVKGKFQDNFEFVQWFKRFFDANYDG 396
KF LEHEYI NFKVLQ+ FKK GVDK PV KLVKGKFQDNFEFVQWFK+FFDANYDG
Sbjct: 62 KFQAKLEHEYIQNFKVLQAGFKKMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYDG 121
Query: 397 HEYDPLAARGGEIVQGTGRNAVKPSGDSLQRPNYSAPRRASATNAITKPTAVKQSTAPKP 576
+YDP+AAR G+ +S P +AP + Q T P
Sbjct: 122 KDYDPVAARQGQ--------------ESAPVPVLAAPVLNKPKKPLGSGNTAPQRTVPVQ 167
Query: 577 AMIRPSAQPTQQSKVSPAGSHNSVTINGGDQAEVGKLRKAIESLTLQSEDDKTTIDNLMR 756
+ P Q PA T+ GD E +L + I L K T+++L +
Sbjct: 168 RTAVSNKPPAQGISKKPA------TVGNGDD-ESAELIQQINVL-------KITVEDLEK 213
Query: 757 ERDFYFNKLRDIEVL 801
ERDFYF KLR+IE++
Sbjct: 214 ERDFYFGKLRNIELI 228
>sp|Q6V291|MARE1_COTCO Microtubule-associated protein RP/EB family member 1
Length = 263
Score = 226 bits (577), Expect = 4e-59
Identities = 124/255 (48%), Positives = 155/255 (60%)
Frame = +1
Query: 37 AVNVYSTNQTSDNVSRNDIIAWINGCLDVNVGKIEELCNGALYCHLMDMLFPGTLQFKKI 216
AVNVYST+ TSDN+SR+D++AWIN L + + KIE+LC+GA YC MDMLFPG++ KK+
Sbjct: 2 AVNVYSTSVTSDNLSRHDMLAWINESLQLTLTKIEQLCSGAAYCQFMDMLFPGSVALKKV 61
Query: 217 KFNTNLEHEYINNFKVLQSLFKKHGVDKEAPVSKLVKGKFQDNFEFVQWFKRFFDANYDG 396
KF LEHEYI NFKVLQ+ FK+ GVDK PV KLVKGKFQDNFEFVQWFK+FFDANYDG
Sbjct: 62 KFQAKLEHEYIQNFKVLQAGFKRMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYDG 121
Query: 397 HEYDPLAARGGEIVQGTGRNAVKPSGDSLQRPNYSAPRRASATNAITKPTAVKQSTAPKP 576
EYDP+AAR G PN AP N KP + +P
Sbjct: 122 KEYDPVAAR---------------QGQETVAPNLVAP----VMNKPKKPLGTGSAAPQRP 162
Query: 577 AMIRPSAQPTQQSKVSPAGSHNSVTINGGDQAEVGKLRKAIESLTLQSEDDKTTIDNLMR 756
+ Q++ +P G V GD G IE + + K T+++L +
Sbjct: 163 IV-------AQRTPATPKGGTGMVKKAAGDDESAG----LIEQINVL----KLTVEDLEK 207
Query: 757 ERDFYFNKLRDIEVL 801
ERDFYF KLR+IE++
Sbjct: 208 ERDFYFGKLRNIELI 222
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,138,217
Number of Sequences: 369166
Number of extensions: 1710609
Number of successful extensions: 6145
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5762
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6104
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7618580670
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)