Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_020_M23 (813 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O00401|WASL_HUMAN Neural Wiskott-Aldrich syndrome protei... 54 5e-07 sp|Q91YD9|WASL_MOUSE Neural Wiskott-Aldrich syndrome protei... 54 5e-07 sp|Q95107|WASL_BOVIN Neural Wiskott-Aldrich syndrome protei... 54 5e-07 sp|O08816|WASL_RAT Neural Wiskott-Aldrich syndrome protein ... 54 5e-07 sp|P42768|WASP_HUMAN Wiskott-Aldrich syndrome protein (WASp) 47 8e-05 sp|P70315|WASP_MOUSE Wiskott-Aldrich syndrome protein homol... 47 8e-05 sp|O13731|UBR11_SCHPO Ubiquitin-protein ligase E3 component... 31 3.5 sp|O14604|TYBY_HUMAN Thymosin beta-4, Y-chromosomal 31 4.6 sp|P20065|TYB4_MOUSE Thymosin beta-4 (T beta 4) [Contains: ... 30 6.0 sp|P55308|CATA2_HORVU Catalase isozyme 2 30 6.0
>sp|O00401|WASL_HUMAN Neural Wiskott-Aldrich syndrome protein (N-WASP) Length = 505 Score = 53.9 bits (128), Expect = 5e-07 Identities = 34/88 (38%), Positives = 47/88 (53%), Gaps = 3/88 (3%) Frame = -3 Query: 811 TKNDISIPTNFQHLDHMGL--NDHFFTSENDENLKKYFKGTQF-EHLLEDKNNLKDIYDF 641 TK DI P+NFQH+ H+G N F + D LK F E L+D+ K IYDF Sbjct: 199 TKADIGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCGISEAQLKDRETSKVIYDF 258 Query: 640 VEKHGGMSKLETEMKQKENKERRAPAIP 557 +EK GG+ ++ E++ R+AP P Sbjct: 259 IEKTGGVEAVKNELR------RQAPPPP 280
>sp|Q91YD9|WASL_MOUSE Neural Wiskott-Aldrich syndrome protein (N-WASP) Length = 501 Score = 53.9 bits (128), Expect = 5e-07 Identities = 34/88 (38%), Positives = 47/88 (53%), Gaps = 3/88 (3%) Frame = -3 Query: 811 TKNDISIPTNFQHLDHMGL--NDHFFTSENDENLKKYFKGTQF-EHLLEDKNNLKDIYDF 641 TK DI P+NFQH+ H+G N F + D LK F E L+D+ K IYDF Sbjct: 196 TKADIGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCGISEAQLKDRETSKVIYDF 255 Query: 640 VEKHGGMSKLETEMKQKENKERRAPAIP 557 +EK GG+ ++ E++ R+AP P Sbjct: 256 IEKTGGVEAVKNELR------RQAPPPP 277
>sp|Q95107|WASL_BOVIN Neural Wiskott-Aldrich syndrome protein (N-WASP) Length = 505 Score = 53.9 bits (128), Expect = 5e-07 Identities = 34/88 (38%), Positives = 47/88 (53%), Gaps = 3/88 (3%) Frame = -3 Query: 811 TKNDISIPTNFQHLDHMGL--NDHFFTSENDENLKKYFKGTQF-EHLLEDKNNLKDIYDF 641 TK DI P+NFQH+ H+G N F + D LK F E L+D+ K IYDF Sbjct: 199 TKADIGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCGISEAQLKDRETSKVIYDF 258 Query: 640 VEKHGGMSKLETEMKQKENKERRAPAIP 557 +EK GG+ ++ E++ R+AP P Sbjct: 259 IEKTGGVEAVKNELR------RQAPPPP 280
>sp|O08816|WASL_RAT Neural Wiskott-Aldrich syndrome protein (N-WASP) Length = 501 Score = 53.9 bits (128), Expect = 5e-07 Identities = 34/88 (38%), Positives = 47/88 (53%), Gaps = 3/88 (3%) Frame = -3 Query: 811 TKNDISIPTNFQHLDHMGL--NDHFFTSENDENLKKYFKGTQF-EHLLEDKNNLKDIYDF 641 TK DI P+NFQH+ H+G N F + D LK F E L+D+ K IYDF Sbjct: 196 TKADIGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCGISEAQLKDRETSKVIYDF 255 Query: 640 VEKHGGMSKLETEMKQKENKERRAPAIP 557 +EK GG+ ++ E++ R+AP P Sbjct: 256 IEKTGGVEAVKNELR------RQAPPPP 277
>sp|P42768|WASP_HUMAN Wiskott-Aldrich syndrome protein (WASp) Length = 502 Score = 46.6 bits (109), Expect = 8e-05 Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 3/78 (3%) Frame = -3 Query: 811 TKNDISIPTNFQHLDHMGLNDH--FFTSENDENLKKYFKGTQF-EHLLEDKNNLKDIYDF 641 +K DI P+ F+H+ H+G + F + D +L+ F E L D K IYDF Sbjct: 234 SKADIGAPSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDF 293 Query: 640 VEKHGGMSKLETEMKQKE 587 +E GG+ + EM+++E Sbjct: 294 IEDQGGLEAVRQEMRRQE 311
>sp|P70315|WASP_MOUSE Wiskott-Aldrich syndrome protein homolog (WASp) Length = 520 Score = 46.6 bits (109), Expect = 8e-05 Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 3/78 (3%) Frame = -3 Query: 811 TKNDISIPTNFQHLDHMGLNDH--FFTSENDENLKKYFKGTQF-EHLLEDKNNLKDIYDF 641 +K DI P+ F+H+ H+G + F + D +L+ F E L D K IYDF Sbjct: 236 SKADIGAPSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDF 295 Query: 640 VEKHGGMSKLETEMKQKE 587 +E GG+ + EM+++E Sbjct: 296 IEDQGGLEAVRQEMRRQE 313
>sp|O13731|UBR11_SCHPO Ubiquitin-protein ligase E3 component N-recognin-11 (N-end-recognizing protein 11) Length = 2052 Score = 31.2 bits (69), Expect = 3.5 Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 3/51 (5%) Frame = -3 Query: 691 FEHLLEDKNNLKDIYDFVEKHGGMSKLETE-MKQKENKERRA--PAIPKNT 548 F+H L+D N++ D+ DF + + L E M+ +EN+ A P + +NT Sbjct: 435 FDHPLDDDNDVNDLLDFETEREDIDDLTDEVMETEENEAAEADYPGVNRNT 485
>sp|O14604|TYBY_HUMAN Thymosin beta-4, Y-chromosomal Length = 44 Score = 30.8 bits (68), Expect = 4.6 Identities = 14/30 (46%), Positives = 18/30 (60%) Frame = -3 Query: 313 LSEIVKFDTKKLKNNQNNPRPPLKSKEANE 224 ++EI KFD KLK + + PL SKE E Sbjct: 7 MAEIEKFDKSKLKKTETQEKNPLSSKETIE 36
>sp|P20065|TYB4_MOUSE Thymosin beta-4 (T beta 4) [Contains: Hematopoietic system regulatory peptide (Seraspenide)] Length = 50 Score = 30.4 bits (67), Expect = 6.0 Identities = 14/30 (46%), Positives = 18/30 (60%) Frame = -3 Query: 313 LSEIVKFDTKKLKNNQNNPRPPLKSKEANE 224 ++EI KFD KLK + + PL SKE E Sbjct: 13 MAEIEKFDKSKLKKTETQEKNPLPSKETIE 42
>sp|P55308|CATA2_HORVU Catalase isozyme 2 Length = 494 Score = 30.4 bits (67), Expect = 6.0 Identities = 10/24 (41%), Positives = 18/24 (75%) Frame = -3 Query: 805 NDISIPTNFQHLDHMGLNDHFFTS 734 +D+ IPT+++H+D G+N + F S Sbjct: 191 DDVGIPTDYRHMDGFGVNTYTFVS 214
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 68,079,351 Number of Sequences: 369166 Number of extensions: 1052584 Number of successful extensions: 3176 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3097 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3168 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 7763237265 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)