Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_020_K21 (806 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q92743|HTRA1_HUMAN Serine protease HTRA1 precursor (L56) 54 4e-07 sp|P83105|HTRA4_HUMAN Probable serine protease HTRA4 precursor 52 2e-06 sp|P83110|HTRA3_HUMAN Probable serine protease HTRA3 precur... 51 3e-06 sp|Q9R118|HTRA1_MOUSE Serine protease HTRA1 precursor 50 6e-06 sp|Q9D236|HTRA3_MOUSE Probable serine protease HTRA3 precur... 47 5e-05 sp|Q9JIY5|HTRA2_MOUSE Serine protease HTRA2, mitochondrial ... 47 5e-05 sp|Q9PL97|DEGP_CHLMU Probable serine protease do-like precu... 47 6e-05 sp|P18584|DEGP_CHLTR Probable serine protease do-like precu... 47 8e-05 sp|Q9Z6T0|DEGP_CHLPN Probable serine protease do-like precu... 47 8e-05 sp|P26982|DEGP_SALTY Protease do precursor 46 1e-04
>sp|Q92743|HTRA1_HUMAN Serine protease HTRA1 precursor (L56) Length = 480 Score = 54.3 bits (129), Expect = 4e-07 Identities = 33/93 (35%), Positives = 46/93 (49%), Gaps = 6/93 (6%) Frame = +3 Query: 204 NDQINSFNFIADVVETITPSVVSITXXXXXXXXXXXXXXXX------DESGYILTNAHVV 365 N + +NFIADVVE I P+VV I E G I+TNAHVV Sbjct: 163 NSLRHKYNFIADVVEKIAPAVVHIELFRKLPFSKREVPVASGSGFIVSEDGLIVTNAHVV 222 Query: 366 VKNPYVSVALSDGQKFQGEVIAIDKTSDLALIK 464 V V L +G ++ ++ +D+ +D+ALIK Sbjct: 223 TNKHRVKVELKNGATYEAKIKDVDEKADIALIK 255
>sp|P83105|HTRA4_HUMAN Probable serine protease HTRA4 precursor Length = 476 Score = 52.0 bits (123), Expect = 2e-06 Identities = 32/94 (34%), Positives = 45/94 (47%), Gaps = 6/94 (6%) Frame = +3 Query: 219 SFNFIADVVETITPSVVSITXXXXXXXXXXXXXXXX------DESGYILTNAHVVVKNPY 380 ++NFIA VVE + PSVV + E G I+TNAHVV + Sbjct: 166 NYNFIAAVVEKVAPSVVHVQLWGRLLHGSRLVPVYSGSGFIVSEDGLIITNAHVVRNQQW 225 Query: 381 VSVALSDGQKFQGEVIAIDKTSDLALIKCNINQQ 482 + V L +G +++ V ID DLA+IK N + Sbjct: 226 IEVVLQNGARYEAVVKDIDLKLDLAVIKIESNAE 259
>sp|P83110|HTRA3_HUMAN Probable serine protease HTRA3 precursor (High-temperature requirement factor A3) (Pregnancy-related serine protease) Length = 453 Score = 51.2 bits (121), Expect = 3e-06 Identities = 35/93 (37%), Positives = 44/93 (47%), Gaps = 12/93 (12%) Frame = +3 Query: 222 FNFIADVVETITPSVVSI------TXXXXXXXXXXXXXXXXDESGYILTNAHVVVKN--- 374 FNFIADVVE I P+VV I E+G I+TNAHVV N Sbjct: 140 FNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSSGSGFIMSEAGLIITNAHVVSSNSAA 199 Query: 375 ---PYVSVALSDGQKFQGEVIAIDKTSDLALIK 464 + V L +G ++ + IDK SD+A IK Sbjct: 200 PGRQQLKVQLQNGDSYEATIKDIDKKSDIATIK 232
>sp|Q9R118|HTRA1_MOUSE Serine protease HTRA1 precursor Length = 480 Score = 50.4 bits (119), Expect = 6e-06 Identities = 31/93 (33%), Positives = 43/93 (46%), Gaps = 6/93 (6%) Frame = +3 Query: 204 NDQINSFNFIADVVETITPSVVS------ITXXXXXXXXXXXXXXXXDESGYILTNAHVV 365 N + +NFIADVVE P VV + E G I+TNAHVV Sbjct: 163 NSLRHKYNFIADVVEKFAPDVVKHELYRKLPFSKREVPVASGSGFIVSEDGLIVTNAHVV 222 Query: 366 VKNPYVSVALSDGQKFQGEVIAIDKTSDLALIK 464 V V L +G ++ + +D+ +D+ALIK Sbjct: 223 TNKNRVKVELKNGATYEAIIKDVDEKADIALIK 255
>sp|Q9D236|HTRA3_MOUSE Probable serine protease HTRA3 precursor (High-temperature requirement factor A3) (Toll-associated serine protease) Length = 460 Score = 47.4 bits (111), Expect = 5e-05 Identities = 34/92 (36%), Positives = 43/92 (46%), Gaps = 12/92 (13%) Frame = +3 Query: 222 FNFIADVVETITPSVVSI------TXXXXXXXXXXXXXXXXDESGYILTNAHVVVKNPYV 383 FNFIADVVE I P+VV I E+G I+TNAHVV + Sbjct: 146 FNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSSGSGFIMSEAGLIVTNAHVVSSSSTA 205 Query: 384 S------VALSDGQKFQGEVIAIDKTSDLALI 461 S V L +G ++ + IDK SD+A I Sbjct: 206 SGRQQLKVQLQNGDAYEATIQDIDKKSDIATI 237
>sp|Q9JIY5|HTRA2_MOUSE Serine protease HTRA2, mitochondrial precursor (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI) Length = 458 Score = 47.4 bits (111), Expect = 5e-05 Identities = 32/106 (30%), Positives = 45/106 (42%), Gaps = 6/106 (5%) Frame = +3 Query: 165 LKPILSVNAASSRNDQINSFNFIADVVETITPSVVSITXXXXXXXXXXXXXXXXDES--- 335 L +L+ A + +NFIADVVE P+VV I Sbjct: 128 LSTVLAAVPAPPPTSPRSQYNFIADVVEKTAPAVVYIEILDRHPFSGREVPISNGSGFVV 187 Query: 336 ---GYILTNAHVVVKNPYVSVALSDGQKFQGEVIAIDKTSDLALIK 464 G I+TNAHVV V V L G ++ V A+D +D+A ++ Sbjct: 188 ASDGLIVTNAHVVADRRRVRVRLPSGDTYEAMVTAVDPVADIATLR 233
>sp|Q9PL97|DEGP_CHLMU Probable serine protease do-like precursor Length = 497 Score = 47.0 bits (110), Expect = 6e-05 Identities = 21/45 (46%), Positives = 30/45 (66%) Frame = +3 Query: 330 ESGYILTNAHVVVKNPYVSVALSDGQKFQGEVIAIDKTSDLALIK 464 E GY++TN HVV + V L DGQK+ ++I +D +DLA+IK Sbjct: 134 EDGYVVTNHHVVEDAGKIHVTLHDGQKYTAKIIGLDPKTDLAVIK 178
>sp|P18584|DEGP_CHLTR Probable serine protease do-like precursor (59 kDa immunogenic protein) (SK59) Length = 497 Score = 46.6 bits (109), Expect = 8e-05 Identities = 20/45 (44%), Positives = 30/45 (66%) Frame = +3 Query: 330 ESGYILTNAHVVVKNPYVSVALSDGQKFQGEVIAIDKTSDLALIK 464 E GY++TN HVV + V L DGQK+ +++ +D +DLA+IK Sbjct: 134 EDGYVVTNHHVVEDAGKIHVTLHDGQKYTAKIVGLDPKTDLAVIK 178
>sp|Q9Z6T0|DEGP_CHLPN Probable serine protease do-like precursor Length = 488 Score = 46.6 bits (109), Expect = 8e-05 Identities = 25/50 (50%), Positives = 31/50 (62%) Frame = +3 Query: 336 GYILTNAHVVVKNPYVSVALSDGQKFQGEVIAIDKTSDLALIKCNINQQN 485 GYI+TN HVV + V L DGQK+ VI +D +DLA+IK I QN Sbjct: 127 GYIVTNNHVVEDTGKIHVTLHDGQKYPATVIGLDPKTDLAVIK--IKSQN 174
>sp|P26982|DEGP_SALTY Protease do precursor Length = 475 Score = 45.8 bits (107), Expect = 1e-04 Identities = 21/43 (48%), Positives = 29/43 (67%) Frame = +3 Query: 336 GYILTNAHVVVKNPYVSVALSDGQKFQGEVIAIDKTSDLALIK 464 GY++TN HVV + V LSDG+KF +V+ D SD+ALI+ Sbjct: 125 GYVVTNNHVVDNASVIKVQLSDGRKFDAKVVGKDPRSDIALIQ 167
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 85,331,904 Number of Sequences: 369166 Number of extensions: 1579802 Number of successful extensions: 3820 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3693 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3809 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 7666799535 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)