Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_020_I22
(822 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9JHW0|PSB7_RAT Proteasome subunit beta type 7 precursor... 274 2e-73
sp|Q99436|PSB7_HUMAN Proteasome subunit beta type 7 precurs... 272 9e-73
sp|P70195|PSB7_MOUSE Proteasome subunit beta type 7 precurs... 270 4e-72
sp|Q09841|PSB7_SCHPO Probable proteasome subunit beta type ... 250 3e-66
sp|Q7DLS1|PSB7B_ARATH Proteasome subunit beta type 7-B prec... 244 2e-64
sp|O23710|PSB7A_ARATH Proteasome subunit beta type 7-A prec... 243 5e-64
sp|P40306|PSB10_HUMAN Proteasome subunit beta type 10 precu... 239 9e-63
sp|O35955|PSBA_MOUSE Proteasome subunit beta type 10 precur... 239 9e-63
sp|P25043|PSB7_YEAST Proteasome component PUP1 precursor (M... 229 9e-60
sp|P93395|PSB6_TOBAC Proteasome subunit beta type 6 precurs... 110 4e-24
>sp|Q9JHW0|PSB7_RAT Proteasome subunit beta type 7 precursor (Proteasome subunit Z)
(Macropain chain Z) (Multicatalytic endopeptidase
complex chain Z)
Length = 277
Score = 274 bits (700), Expect = 2e-73
Identities = 133/232 (57%), Positives = 172/232 (74%)
Frame = +3
Query: 39 RMRKTGTTIVGVIYNEGVVLGADTRATEGNIVAEKNCQKIHYISDNIYCCGAGTAADTEF 218
+ RKTGTTI GV+Y +G+VLGADTRATEG +VA+KNC KIH+IS NIYCCGAGTAADT+
Sbjct: 38 KARKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDM 97
Query: 219 VTRNISSKIRIHHKLGDPRRKPRVVMATHMLKQYLFRYQGHVGAALILGGVDFEGAKLVS 398
T+ ISS + +H R PRVV A MLKQ LFRYQG++GAAL+LGGVD G L S
Sbjct: 98 TTQLISSNLELHSLTTG--RLPRVVTANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYS 155
Query: 399 IHPHGSSDAVPYAAMGSGSLAAISELESLYHPDLTKEEAMELVRRAIRKGIDHDMGSGSN 578
I+PHGS+D +PY MGSGSLAA++ E + PD+ +EEA +LV AI GI +D+GSGSN
Sbjct: 156 IYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKKLVSEAIAAGIFNDLGSGSN 215
Query: 579 VDLCIITKDGAENIRTYEEAHKKGVRFNKYQFPEGTTPLLKSIVRPVEMEIV 734
+DLC+I+K + +R Y +KKG RF +Y+ +GTT +L V P+E+E++
Sbjct: 216 IDLCVISKSKLDFLRPYSVPNKKGTRFGRYRCEKGTTAVLTEKVTPLELEVL 267
>sp|Q99436|PSB7_HUMAN Proteasome subunit beta type 7 precursor (Proteasome subunit Z)
(Macropain chain Z) (Multicatalytic endopeptidase
complex chain Z)
Length = 277
Score = 272 bits (695), Expect = 9e-73
Identities = 131/236 (55%), Positives = 173/236 (73%)
Frame = +3
Query: 39 RMRKTGTTIVGVIYNEGVVLGADTRATEGNIVAEKNCQKIHYISDNIYCCGAGTAADTEF 218
++RKTGTTI GV+Y +G+VLGADTRATEG +VA+KNC KIH+IS NIYCCGAGTAADT+
Sbjct: 38 KVRKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDM 97
Query: 219 VTRNISSKIRIHHKLGDPRRKPRVVMATHMLKQYLFRYQGHVGAALILGGVDFEGAKLVS 398
T+ ISS + +H R PRVV A MLKQ LFRYQG++GAAL+LGGVD G L S
Sbjct: 98 TTQLISSNLELHSL--STGRLPRVVTANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYS 155
Query: 399 IHPHGSSDAVPYAAMGSGSLAAISELESLYHPDLTKEEAMELVRRAIRKGIDHDMGSGSN 578
I+PHGS+D +PY MGSGSLAA++ E + PD+ +EEA LV AI GI +D+GSGSN
Sbjct: 156 IYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSN 215
Query: 579 VDLCIITKDGAENIRTYEEAHKKGVRFNKYQFPEGTTPLLKSIVRPVEMEIVSTRI 746
+DLC+I+K+ + +R Y +KKG R +Y+ +GTT +L + P+E+E++ +
Sbjct: 216 IDLCVISKNKLDFLRPYTVPNKKGTRLGRYRCEKGTTAVLTEKITPLEIEVLEETV 271
>sp|P70195|PSB7_MOUSE Proteasome subunit beta type 7 precursor (Proteasome subunit Z)
(Macropain chain Z) (Multicatalytic endopeptidase
complex chain Z)
Length = 277
Score = 270 bits (690), Expect = 4e-72
Identities = 131/236 (55%), Positives = 172/236 (72%)
Frame = +3
Query: 39 RMRKTGTTIVGVIYNEGVVLGADTRATEGNIVAEKNCQKIHYISDNIYCCGAGTAADTEF 218
+ RKTGTTI GV+Y +G+VLGADTRATEG +VA+KNC KIH+IS NIYCCGAGTAADT+
Sbjct: 38 KARKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDM 97
Query: 219 VTRNISSKIRIHHKLGDPRRKPRVVMATHMLKQYLFRYQGHVGAALILGGVDFEGAKLVS 398
T+ ISS + +H R PRVV A MLKQ LFRYQG++GAAL+LGGVD G L S
Sbjct: 98 TTQLISSNLELHSLTTG--RLPRVVTANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYS 155
Query: 399 IHPHGSSDAVPYAAMGSGSLAAISELESLYHPDLTKEEAMELVRRAIRKGIDHDMGSGSN 578
I+PHGS+D +PY MGSGSLAA++ E + PD+ +EEA +LV AI GI +D+GSGSN
Sbjct: 156 IYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKKLVSEAIAAGIFNDLGSGSN 215
Query: 579 VDLCIITKDGAENIRTYEEAHKKGVRFNKYQFPEGTTPLLKSIVRPVEMEIVSTRI 746
+DLC+I+K + +R + +KKG R +Y+ +GTT +L V P+E+E++ +
Sbjct: 216 IDLCVISKSKLDFLRPFSVPNKKGTRLGRYRCEKGTTAVLTEKVTPLEIEVLEETV 271
>sp|Q09841|PSB7_SCHPO Probable proteasome subunit beta type 7 precursor
Length = 267
Score = 250 bits (639), Expect = 3e-66
Identities = 132/249 (53%), Positives = 173/249 (69%)
Frame = +3
Query: 33 TSRMRKTGTTIVGVIYNEGVVLGADTRATEGNIVAEKNCQKIHYISDNIYCCGAGTAADT 212
T + TGTTIVGVI + +VLGADTRAT G I+A+KNC+K+H IS NI+C GAGTAADT
Sbjct: 28 TPKATSTGTTIVGVIAKDCIVLGADTRATAGPIIADKNCKKLHLISPNIWCAGAGTAADT 87
Query: 213 EFVTRNISSKIRIHHKLGDPRRKPRVVMATHMLKQYLFRYQGHVGAALILGGVDFEGAKL 392
EFVT ISS I +H + RKPRVV A MLKQ+LFRYQGH+GA L+LGG D +G L
Sbjct: 88 EFVTSMISSNIELHSLYTN--RKPRVVTALTMLKQHLFRYQGHIGAYLVLGGYDCKGPHL 145
Query: 393 VSIHPHGSSDAVPYAAMGSGSLAAISELESLYHPDLTKEEAMELVRRAIRKGIDHDMGSG 572
+I HGSSD +PY A+GSGSLAAIS LE+ Y PDL + EAMELV+ AI GI +D+GSG
Sbjct: 146 FTIAAHGSSDKLPYVALGSGSLAAISVLETKYQPDLERHEAMELVKEAIEAGIFNDLGSG 205
Query: 573 SNVDLCIITKDGAENIRTYEEAHKKGVRFNKYQFPEGTTPLLKSIVRPVEMEIVSTRIIR 752
SN DL +I ++ A R Y + +++ + +KY + GTT +LK +I ++
Sbjct: 206 SNCDLVVIDEEKATPYRGYSKPNERATKQSKYTYDRGTTAVLKE-------DIYKFVTVQ 258
Query: 753 DLPQEEMEI 779
DL + ++++
Sbjct: 259 DLDEMQVDV 267
>sp|Q7DLS1|PSB7B_ARATH Proteasome subunit beta type 7-B precursor (Proteasome subunit beta
type 2) (20S proteasome beta subunit B-2) (Proteasome
component FC)
Length = 274
Score = 244 bits (624), Expect = 2e-64
Identities = 130/231 (56%), Positives = 168/231 (72%), Gaps = 2/231 (0%)
Frame = +3
Query: 48 KTGTTIVGVIYNEGVVLGADTRATEGNIVAEKNCQKIHYISDNIYCCGAGTAADTEFVTR 227
KTGTTIVG+I+ +GV+LGADTRATEG IVA+KNC+KIHY++ NIYCCGAGTAADTE VT
Sbjct: 37 KTGTTIVGLIFKDGVILGADTRATEGPIVADKNCEKIHYMAPNIYCCGAGTAADTEAVTD 96
Query: 228 NISSKIRIHHKLGDPRRKPRVVMATHMLKQYLFRYQGHVGAALILGGVDFEGAKLVSIHP 407
+SS++R+H R RVV A +LK++LF YQGHV AAL+LGGVD G L +I+P
Sbjct: 97 MVSSQLRLHRY--QTGRDSRVVTALTLLKKHLFSYQGHVSAALVLGGVDITGPHLHTIYP 154
Query: 408 HGSSDAVPYAAMGSGSLAAISELESLYHPDLTKEEAMELVRRAIRKGIDHDMGSGSNVDL 587
HGS+D +P+A MGSGSLAA+S E+ Y LT++E ++LV AI GI +D+GSGSNVD+
Sbjct: 155 HGSTDTLPFATMGSGSLAAMSVFEAKYKEGLTRDEGIKLVAEAICSGIFNDLGSGSNVDI 214
Query: 588 CIITKDGAENIRTYEEAHKKGVRFNK-YQFPEGTTPLLKSIVRPVE-MEIV 734
C+ITK E +R Y E + + +K Y F + T LL I +E +EIV
Sbjct: 215 CVITKGHKEYLRNYMEPNPRTYVSSKGYSFTKKTEVLLTKITPLLERVEIV 265
>sp|O23710|PSB7A_ARATH Proteasome subunit beta type 7-A precursor (Proteasome subunit beta
type 2) (20S proteasome beta subunit B-1) (Proteasome
component FA) (Proteasome component FB)
Length = 273
Score = 243 bits (620), Expect = 5e-64
Identities = 125/226 (55%), Positives = 164/226 (72%), Gaps = 1/226 (0%)
Frame = +3
Query: 48 KTGTTIVGVIYNEGVVLGADTRATEGNIVAEKNCQKIHYISDNIYCCGAGTAADTEFVTR 227
KTGTTIVG+I+ +GV+LGADTRATEG IVA+KNC+KIHY++ NIYCCGAGTAADTE VT
Sbjct: 37 KTGTTIVGLIFKDGVILGADTRATEGPIVADKNCEKIHYMAPNIYCCGAGTAADTEAVTD 96
Query: 228 NISSKIRIHHKLGDPRRKPRVVMATHMLKQYLFRYQGHVGAALILGGVDFEGAKLVSIHP 407
+SS++R+H R RV+ A +LK++LF YQGHV AAL+LGGVD G L +I+P
Sbjct: 97 MVSSQLRLHRY--QTGRDSRVITALTLLKKHLFSYQGHVSAALVLGGVDITGPHLHTIYP 154
Query: 408 HGSSDAVPYAAMGSGSLAAISELESLYHPDLTKEEAMELVRRAIRKGIDHDMGSGSNVDL 587
HGS+D +P+A MGSGSLAA+S E+ Y LT++E ++LV +I GI +D+GSGSNVD+
Sbjct: 155 HGSTDTLPFATMGSGSLAAMSVFEAKYKEGLTRDEGIKLVAESICSGIFNDLGSGSNVDI 214
Query: 588 CIITKDGAENIRTYEEAHKKGVRFNK-YQFPEGTTPLLKSIVRPVE 722
C+ITK E +R Y E + + +K Y F + T LL I +E
Sbjct: 215 CVITKGNKEYLRNYMEPNPRTYVSSKGYSFTKKTEVLLTKITPLLE 260
>sp|P40306|PSB10_HUMAN Proteasome subunit beta type 10 precursor (Proteasome MECl-1)
(Macropain subunit MECl-1) (Multicatalytic endopeptidase
complex subunit MECl-1)
Length = 273
Score = 239 bits (609), Expect = 9e-63
Identities = 115/234 (49%), Positives = 160/234 (68%)
Frame = +3
Query: 45 RKTGTTIVGVIYNEGVVLGADTRATEGNIVAEKNCQKIHYISDNIYCCGAGTAADTEFVT 224
RKTGTTI G+++ +GV+LGADTRAT ++VA+K+C+KIH+I+ IYCCGAG AAD E T
Sbjct: 36 RKTGTTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEMTT 95
Query: 225 RNISSKIRIHHKLGDPRRKPRVVMATHMLKQYLFRYQGHVGAALILGGVDFEGAKLVSIH 404
R ++SK+ +H R+PRV T +L+Q LFRYQGHVGA+LI+GGVD G +L +H
Sbjct: 96 RMVASKMELHAL--STGREPRVATVTRILRQTLFRYQGHVGASLIVGGVDLTGPQLYGVH 153
Query: 405 PHGSSDAVPYAAMGSGSLAAISELESLYHPDLTKEEAMELVRRAIRKGIDHDMGSGSNVD 584
PHGS +P+ A+GSG AA++ LE + P++T E A L+ A+ GI D+GSG NVD
Sbjct: 154 PHGSYSRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEAVTAGILGDLGSGGNVD 213
Query: 585 LCIITKDGAENIRTYEEAHKKGVRFNKYQFPEGTTPLLKSIVRPVEMEIVSTRI 746
C+ITK GA+ +RT + R +Y F GTT +L V+P+ +E+V +
Sbjct: 214 ACVITKTGAKLLRTLSSPTEPVKRSGRYHFVPGTTAVLTQTVKPLTLELVEETV 267
>sp|O35955|PSBA_MOUSE Proteasome subunit beta type 10 precursor (Proteasome MECl-1)
(Macropain subunit MECl-1) (Multicatalytic endopeptidase
complex subunit MECl-1)
Length = 273
Score = 239 bits (609), Expect = 9e-63
Identities = 116/234 (49%), Positives = 160/234 (68%)
Frame = +3
Query: 45 RKTGTTIVGVIYNEGVVLGADTRATEGNIVAEKNCQKIHYISDNIYCCGAGTAADTEFVT 224
RKTGTTI G+++ +GV+LGADTRAT ++VA+K+C+KIH+I+ IYCCGAG AADTE T
Sbjct: 36 RKTGTTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADTEMTT 95
Query: 225 RNISSKIRIHHKLGDPRRKPRVVMATHMLKQYLFRYQGHVGAALILGGVDFEGAKLVSIH 404
R +SK+ +H R+PRV T +L+Q LFRYQGHVGA+L++GGVD G +L +H
Sbjct: 96 RMAASKMELHAL--STGREPRVATVTRILRQTLFRYQGHVGASLVVGGVDLNGPQLYEVH 153
Query: 405 PHGSSDAVPYAAMGSGSLAAISELESLYHPDLTKEEAMELVRRAIRKGIDHDMGSGSNVD 584
PHGS +P+ A+GSG AA++ LE + P++T E A EL+ AI GI D+GSG NVD
Sbjct: 154 PHGSYSRLPFTALGSGQGAAVALLEDRFQPNMTLEAAQELLVEAITAGILSDLGSGGNVD 213
Query: 585 LCIITKDGAENIRTYEEAHKKGVRFNKYQFPEGTTPLLKSIVRPVEMEIVSTRI 746
C+IT GA+ R + R +Y+F GTTP+L VRP+ +E++ +
Sbjct: 214 ACVITAGGAKLQRALSTPTEPVQRAGRYRFAPGTTPVLTREVRPLTLELLEETV 267
>sp|P25043|PSB7_YEAST Proteasome component PUP1 precursor (Macropain subunit PUP1)
(Proteinase YSCE subunit PUP1) (Multicatalytic
endopeptidase complex subunit PUP1)
Length = 261
Score = 229 bits (583), Expect = 9e-60
Identities = 131/246 (53%), Positives = 170/246 (69%), Gaps = 3/246 (1%)
Frame = +3
Query: 51 TGTTIVGVIYNEGVVLGADTRATEGNIVAEKNCQKIHYISDNIYCCGAGTAADTEFVTRN 230
TGTTIVGV +N GVV+ ADTR+T+G IVA+KNC K+H IS I+C GAGTAADTE VT+
Sbjct: 28 TGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQL 87
Query: 231 ISSKIRIHHKLGDPRRKPRVVMATHMLKQYLFRYQGHVGAALILGGVDFEGAKLVSIHPH 410
I S I +H R+PRVV A MLKQ+LF+YQGH+GA LI+ GVD G+ L SIH H
Sbjct: 88 IGSNIELHSLYTS--REPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAH 145
Query: 411 GSSDAVPYAAMGSGSLAAISELESLYHPDLTKEEAMELVRRAIRKGIDHDMGSGSNVDLC 590
GS+D Y ++GSGSLAA++ LES + DLTKEEA++L AI+ GI +D+GSGSNVD+C
Sbjct: 146 GSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVC 205
Query: 591 I--ITKDGAENIRTYEEAHKKGVRFNKYQFPEGTTPLLK-SIVRPVEMEIVSTRIIRDLP 761
+ I KD AE +R Y + + + Y+FP GTT +LK SIV I D+
Sbjct: 206 VMEIGKD-AEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVN-----------ICDIQ 253
Query: 762 QEEMEI 779
+E+++I
Sbjct: 254 EEQVDI 259
>sp|P93395|PSB6_TOBAC Proteasome subunit beta type 6 precursor (Proteasome delta chain)
(Tobacco cryptogein-induced protein 7) (tcI 7)
Length = 234
Score = 110 bits (276), Expect = 4e-24
Identities = 69/188 (36%), Positives = 103/188 (54%), Gaps = 2/188 (1%)
Frame = +3
Query: 54 GTTIVGVIYNEGVVLGADTRATEGNIVAEKNCQKIHYISDNIYCCGAGTAADTEFVTRNI 233
GTTI+GV YN GVVLGAD+R + G VA + KI ++DN+Y C +G+AAD++ V+ +
Sbjct: 13 GTTIIGVTYNGGVVLGADSRTSTGMYVANRASDKITQLTDNVYVCRSGSAADSQIVSDYV 72
Query: 234 SSKIRIHH-KLGDPRRKPRVVMATHMLKQYLFRYQGHVGAALILGGVD-FEGAKLVSIHP 407
+ H +LG P V +A ++ + + + + +I+GG D +EG K+ I P
Sbjct: 73 RYFLHQHTIQLGQP---ATVKVAANLTRLLSYNNKDRLQTGMIIGGWDKYEGGKIYGIPP 129
Query: 408 HGSSDAVPYAAMGSGSLAAISELESLYHPDLTKEEAMELVRRAIRKGIDHDMGSGSNVDL 587
G+ P+A GSGS + + +T+EEA +LV A+ I D SG V
Sbjct: 130 GGTVLEQPFAIGGSGSSYLYGFFDQAWKEGMTQEEAEKLVVTAVSLAIARDGASGGVVRT 189
Query: 588 CIITKDGA 611
I KDGA
Sbjct: 190 VTINKDGA 197
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,717,343
Number of Sequences: 369166
Number of extensions: 1644731
Number of successful extensions: 4831
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4620
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4727
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7907893860
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)