Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_020_I05
(866 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9UG63|ABCF2_HUMAN ATP-binding cassette sub-family F mem... 443 e-124
sp|Q99LE6|ABCF2_MOUSE ATP-binding cassette sub-family F mem... 443 e-124
sp|P40024|YEM6_YEAST Probable ATP-dependent transporter YER... 279 8e-75
sp|P43535|GCN20_YEAST Protein GCN20 220 3e-57
sp|Q6MG08|ABCF1_RAT ATP-binding cassette sub-family F membe... 188 1e-47
sp|Q6P542|ABCF1_MOUSE ATP-binding cassette sub-family F mem... 187 2e-47
sp|Q8NE71|ABCF1_HUMAN ATP-binding cassette sub-family F mem... 186 7e-47
sp|Q7YR37|ABCF1_PANTR ATP-binding cassette sub-family F mem... 186 7e-47
sp|Q767L0|ABCF1_PIG ATP-binding cassette sub-family F member 1 186 9e-47
sp|P63390|YHES_ECO57 Hypothetical ABC transporter ATP-bindi... 159 9e-39
>sp|Q9UG63|ABCF2_HUMAN ATP-binding cassette sub-family F member 2 (Iron-inhibited ABC
transporter 2)
Length = 623
Score = 443 bits (1140), Expect = e-124
Identities = 208/287 (72%), Positives = 249/287 (86%)
Frame = +2
Query: 2 KKLVYYGGNYDQYIMTKMELEENQMKKYKWEQDQMAHMKDYIARFGHGSRKLARQAQSKE 181
KKL YY GNYDQY+ T++ELEENQMK++ WEQDQ+AHMK+YIARFGHGS KLARQAQSKE
Sbjct: 301 KKLKYYTGNYDQYVKTRLELEENQMKRFHWEQDQIAHMKNYIARFGHGSAKLARQAQSKE 360
Query: 182 KTLKKMVDGGLTQKVIREKNLVFSFPSCGEIPPPVIQVQNVSFKYGANKPLIYDNIDFGV 361
KTL+KM+ GLT++V+ +K L F FP CG+IPPPVI VQNVSFKY + P IY+N++FG+
Sbjct: 361 KTLQKMMASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGI 420
Query: 362 DLDTRVALVGPNGAGKSTLLKLIASELEPTDGLIRRHSKCRIGRYHQHLHEILDLNSTAL 541
DLDTRVALVGPNGAGKSTLLKL+ EL PTDG+IR+HS +IGRYHQHL E LDL+ + L
Sbjct: 421 DLDTRVALVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPL 480
Query: 542 EWMMKSFPHIKEKDEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLL 721
E+MMK +P IKEK+EMRK +GRYGLTG QQ+ PI++LSDGQ+CR+ AWLA PHML L
Sbjct: 481 EYMMKCYPEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFL 540
Query: 722 DEPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCD 862
DEPTNHLD+ETID+LADAINEFEGG++LVSHDFRLI +VA+EIWVC+
Sbjct: 541 DEPTNHLDIETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCE 587
Score = 59.7 bits (143), Expect = 1e-08
Identities = 58/184 (31%), Positives = 75/184 (40%), Gaps = 25/184 (13%)
Frame = +2
Query: 374 RVALVGPNGAGKSTLLKLIAS----------------ELEPTDGLIRRHSKCRIGRYHQH 505
R L+G NG GKS LL I E+ P+D H +
Sbjct: 113 RYGLIGLNGIGKSMLLSAIGKREVPIPEHIDIYHLTREMPPSDKT-PLHCVMEVDTERAM 171
Query: 506 LH---EILDLNSTALEWMMKSFPHIKEKD----EMRKK--LGRYGLTGGQQICPIKSLSD 658
L E L E +M+ + ++E D EMR L G T Q +K S
Sbjct: 172 LEKEAERLAHEDAECEKLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSG 231
Query: 659 GQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRV 838
G R R+ A P MLLLDEPTNHLDL+ L + + F+ L+LVSH + V
Sbjct: 232 GWRMRVALARALFIRPFMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGV 291
Query: 839 AEEI 850
I
Sbjct: 292 CTNI 295
>sp|Q99LE6|ABCF2_MOUSE ATP-binding cassette sub-family F member 2
Length = 628
Score = 443 bits (1140), Expect = e-124
Identities = 208/287 (72%), Positives = 249/287 (86%)
Frame = +2
Query: 2 KKLVYYGGNYDQYIMTKMELEENQMKKYKWEQDQMAHMKDYIARFGHGSRKLARQAQSKE 181
KKL YY GNYDQY+ T++ELEENQMK++ WEQDQ+AHMK+YIARFGHGS KLARQAQSKE
Sbjct: 306 KKLKYYTGNYDQYVKTRLELEENQMKRFHWEQDQIAHMKNYIARFGHGSAKLARQAQSKE 365
Query: 182 KTLKKMVDGGLTQKVIREKNLVFSFPSCGEIPPPVIQVQNVSFKYGANKPLIYDNIDFGV 361
KTL+KM+ GLT++V+ +K L F FP CG+IPPPVI VQNVSFKY + P IY+N++FG+
Sbjct: 366 KTLQKMMASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGI 425
Query: 362 DLDTRVALVGPNGAGKSTLLKLIASELEPTDGLIRRHSKCRIGRYHQHLHEILDLNSTAL 541
DLDTRVALVGPNGAGKSTLLKL+ EL PTDG+IR+HS +IGRYHQHL E LDL+ + L
Sbjct: 426 DLDTRVALVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPL 485
Query: 542 EWMMKSFPHIKEKDEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLL 721
E+MMK +P IKEK+EMRK +GRYGLTG QQ+ PI++LSDGQ+CR+ AWLA PHML L
Sbjct: 486 EYMMKCYPEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFL 545
Query: 722 DEPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCD 862
DEPTNHLD+ETID+LADAINEFEGG++LVSHDFRLI +VA+EIWVC+
Sbjct: 546 DEPTNHLDIETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCE 592
Score = 57.0 bits (136), Expect = 7e-08
Identities = 57/183 (31%), Positives = 73/183 (39%), Gaps = 24/183 (13%)
Frame = +2
Query: 374 RVALVGPNGAGKSTLLKLIASELEPTDGLIRRHSKCR---------------IGRYHQHL 508
R L+G NG GKS LL I P I + R + L
Sbjct: 118 RYGLIGLNGIGKSMLLSAIGKREVPIPEHIDIYHLTREMPPSEKTPLQCVMEVDTERAML 177
Query: 509 H---EILDLNSTALEWMMKSFPHIKEKD----EMRKK--LGRYGLTGGQQICPIKSLSDG 661
E L E +M+ + ++E D EMR L G T Q +K S G
Sbjct: 178 EREAERLAHEDAECEKLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGG 237
Query: 662 QRCRIIFAWLAEGCPHMLLLDEPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRVA 841
R R+ A P MLLLDEPTNHLDL+ L + + F+ L+LVSH + V
Sbjct: 238 WRMRVALARALFIRPFMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVC 297
Query: 842 EEI 850
I
Sbjct: 298 TNI 300
>sp|P40024|YEM6_YEAST Probable ATP-dependent transporter YER036C
Length = 610
Score = 279 bits (713), Expect = 8e-75
Identities = 141/290 (48%), Positives = 204/290 (70%), Gaps = 2/290 (0%)
Frame = +2
Query: 2 KKLVYYGGNYDQYIMTKMELEENQMKKYKWEQDQMAHMKDYIARFGHGSRKLARQAQSKE 181
+KL YGGNYD Y T+ ELE NQMK+Y +Q+++ H+K +IA G + L +QA+S++
Sbjct: 299 QKLTAYGGNYDSYHKTRSELETNQMKQYNKQQEEIQHIKKFIASAGTYAN-LVKQAKSRQ 357
Query: 182 KTLKKMVDGGLTQKVIREKNLVFSFPSCGEIPPPVIQVQNVSFKYGAN-KPLIYDNIDFG 358
K L KM GL Q V+ +K F FP +PPPV+ ++SF Y +N +Y++++FG
Sbjct: 358 KILDKMEADGLVQPVVPDKVFSFRFPQVERLPPPVLAFDDISFHYESNPSENLYEHLNFG 417
Query: 359 VDLDTRVALVGPNGAGKSTLLKLIASELEPTDGLIRRHSKCRIGRYHQHLHEILDLNSTA 538
VD+D+R+ALVGPNG GKSTLLK++ EL P G + RH+ ++G Y QH + LDL +A
Sbjct: 418 VDMDSRIALVGPNGVGKSTLLKIMTGELTPQSGRVSRHTHVKLGVYSQHSQDQLDLTKSA 477
Query: 539 LEWMMKSFPHIKEKDEM-RKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHML 715
LE++ + +I + + R +LGRYGLTG Q + +LS+GQR R++FA LA P++L
Sbjct: 478 LEFVRDKYSNISQDFQFWRGQLGRYGLTGEGQTVQMATLSEGQRSRVVFALLALEQPNVL 537
Query: 716 LLDEPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCDH 865
LLDEPTN LD+ TIDSLADAINEF GG+++VSHDFRL+ ++A++I+V ++
Sbjct: 538 LLDEPTNGLDIPTIDSLADAINEFNGGVVVVSHDFRLLDKIAQDIFVVEN 587
Score = 50.1 bits (118), Expect = 8e-06
Identities = 56/205 (27%), Positives = 91/205 (44%), Gaps = 29/205 (14%)
Frame = +2
Query: 287 IQVQNVSFKYGANKPLIYDNIDFGVDLD--TRVALVGPNGAGKSTLLKLIA--------- 433
I++ +VS + K LI D+ G++L+ R L+G NG GKST LK +A
Sbjct: 82 IKLSSVSLLFHG-KVLIQDS---GLELNYGRRYGLLGENGCGKSTFLKALATREYPIPEH 137
Query: 434 ------------SELEPTDGLIRRHSKCRIGRYHQHLHEILDLNSTALEWMMKSFPHIKE 577
SEL D ++ ++ + R + + + + E + + +
Sbjct: 138 IDIYLLDEPAEPSELSALDYVVTE-AQHELKRIEDLVEKTILEDGPESELLEPLYERMDS 196
Query: 578 KD----EMRKKLGRYGLTGGQQ--ICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNH 739
D E R + GL ++ + K +S G + R+ A P +LLLD+PT H
Sbjct: 197 LDPDTFESRAAIILIGLGFNKKTILKKTKDMSGGWKMRVALAKALFVKPTLLLLDDPTAH 256
Query: 740 LDLETIDSLADAINEFEGGLLLVSH 814
LDLE L + + F+ L+LVSH
Sbjct: 257 LDLEACVWLEEYLKRFDRTLVLVSH 281
>sp|P43535|GCN20_YEAST Protein GCN20
Length = 752
Score = 220 bits (561), Expect = 3e-57
Identities = 113/288 (39%), Positives = 187/288 (64%), Gaps = 1/288 (0%)
Frame = +2
Query: 2 KKLVYYGG-NYDQYIMTKMELEENQMKKYKWEQDQMAHMKDYIARFGHGSRKLARQAQSK 178
++L YY G ++D + TK E +N ++Y + H++++I ++ + + K +++AQS+
Sbjct: 440 ERLDYYRGQDFDTFYTTKEERRKNAQREYDNQMVYRKHLQEFIDKYRYNAAK-SQEAQSR 498
Query: 179 EKTLKKMVDGGLTQKVIREKNLVFSFPSCGEIPPPVIQVQNVSFKYGANKPLIYDNIDFG 358
K L+K+ + + ++K + F FP C ++ PP+IQ+Q+VSF Y N L+ D ++
Sbjct: 499 IKKLEKLP---VLEPPEQDKTIDFKFPECDKLSPPIIQLQDVSFGYDENNLLLKD-VNLD 554
Query: 359 VDLDTRVALVGPNGAGKSTLLKLIASELEPTDGLIRRHSKCRIGRYHQHLHEILDLNSTA 538
V +D+R+ALVG NG GK+TLLK++ +L P G + R+ + RIG + QH + +DL ++A
Sbjct: 555 VQMDSRIALVGANGCGKTTLLKIMMEQLRPLKGFVSRNPRLRIGYFTQHHVDSMDLTTSA 614
Query: 539 LEWMMKSFPHIKEKDEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLL 718
++WM KSFP K +E R+ LG +G+TG + ++ LS GQ+ R+ FA L PH+L+
Sbjct: 615 VDWMSKSFPG-KTDEEYRRHLGSFGITGTLGLQKMQLLSGGQKSRVAFAALCLNNPHILV 673
Query: 719 LDEPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCD 862
LDEP+NHLD +D+L +A+ F GG+L+VSHD +I V +EIWV +
Sbjct: 674 LDEPSNHLDTTGLDALVEALKNFNGGVLMVSHDISVIDSVCKEIWVSE 721
Score = 53.1 bits (126), Expect = 1e-06
Identities = 64/222 (28%), Positives = 87/222 (39%), Gaps = 50/222 (22%)
Frame = +2
Query: 335 IYDNIDFGVDLDTRVALVGPNGAGKSTLLKLIAS-ELEPTDGLIRRHSKCRI-GRYHQHL 508
I N + R LVG NG GKSTLL+ ++ EL + H + + G + L
Sbjct: 214 ILSNAQLTLSFGHRYGLVGQNGIGKSTLLRALSRRELNVPKHVSILHVEQELRGDDTKAL 273
Query: 509 HEILDLN---STALEWMMKSFPHIKEKDEMR----------KKLGR-------------- 607
+LD + L K +KE D +R KKL
Sbjct: 274 QSVLDADVWRKQLLSEEAKINERLKEMDVLRQEFEEDSLEVKKLDNEREDLDNHLIQISD 333
Query: 608 ------------------YGL---TGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLD 724
YGL T QQ P S S G R R+ A P +LLLD
Sbjct: 334 KLVDMESDKAEARAASILYGLGFSTEAQQQ-PTNSFSGGWRMRLSLARALFCQPDLLLLD 392
Query: 725 EPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRVAEEI 850
EP+N LD+ +I LA+ + + +L VSHD + VA +I
Sbjct: 393 EPSNMLDVPSIAYLAEYLKTYPNTVLTVSHDRAFLNEVATDI 434
>sp|Q6MG08|ABCF1_RAT ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50)
Length = 839
Score = 188 bits (478), Expect = 1e-47
Identities = 111/299 (37%), Positives = 177/299 (59%), Gaps = 12/299 (4%)
Frame = +2
Query: 2 KKLVYYGGNYDQYIMTKMELEENQMKKYKWEQDQMAHMKDYIARFGHGSRKLARQAQSKE 181
++L YY GNY + + ++ +K+Y+ ++ ++ +K G S K A + Q+KE
Sbjct: 518 QRLHYYRGNYMTFKKMYQQKQKELLKQYEKQEKKLKELKA-----GGKSTKQAEK-QTKE 571
Query: 182 KTLKKMV------------DGGLTQKVIREKNLVFSFPSCGEIPPPVIQVQNVSFKYGAN 325
+K D K RE + F+FP + PPV+ + V+F Y
Sbjct: 572 VLTRKQQKCRRKNQDEESQDPPELLKRpreYTVRFTFPDPPPLSPPVLGLHGVTFGYEGQ 631
Query: 326 KPLIYDNIDFGVDLDTRVALVGPNGAGKSTLLKLIASELEPTDGLIRRHSKCRIGRYHQH 505
KPL + N+DFG+D+D+R+ +VGPNG GKSTLL L+ +L PT+G +R++ + +IG ++Q
Sbjct: 632 KPL-FKNLDFGIDMDSRICIVGPNGVGKSTLLLLLTGKLTPTNGEMRKNHRLKIGFFNQQ 690
Query: 506 LHEILDLNSTALEWMMKSFPHIKEKDEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFA 685
E L + T E++ + F ++ +D RK LGR+GL I LS GQ+ R++FA
Sbjct: 691 YAEQLHMEETPTEYLQRGF-NLPYQDA-RKCLGRFGLESHAHTIQICKLSGGQKARVVFA 748
Query: 686 WLAEGCPHMLLLDEPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCD 862
LA P +L+LDEPTN+LD+E+ID+L +AINE++G +++VSHD RLI ++WV +
Sbjct: 749 ELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVE 807
Score = 70.9 bits (172), Expect = 4e-12
Identities = 72/269 (26%), Positives = 115/269 (42%), Gaps = 38/269 (14%)
Frame = +2
Query: 158 ARQAQSKEKTLKKMVDGGLTQKVIREKNLV---FSFPSCGEIPPPVIQVQNVS------F 310
A ++ ++K LKK +D + ++ N FS S E+ ++N S F
Sbjct: 245 AHLSKKEKKKLKKQMDYERQVESLKAANAAENDFSV-SQAEVSSRQAMLENASDIKLEKF 303
Query: 311 KYGANKPLIYDNIDFGVDLDTRVALVGPNGAGKSTLLK---------------------L 427
A+ ++ N D + R LVGPNG GK+TLLK +
Sbjct: 304 SISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQEV 363
Query: 428 IASELEPTDGLIRRHSK-CRIGRYHQHLHEILDL-NSTALEWMMKSFPHIKE------KD 583
+A E ++R +K R+ + L L+ + TA E + K + ++ +
Sbjct: 364 VADETPAVQAVLRADTKRLRLLEEEKRLQGQLEQGDDTAAEKLEKVYEELRATGAAAAEA 423
Query: 584 EMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETIDS 763
+ R+ L G Q P + S G R R+ A P +L+LDEPTNHLDL +
Sbjct: 424 KARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIW 483
Query: 764 LADAINEFEGGLLLVSHDFRLIGRVAEEI 850
L + + + LL+VSHD + V +I
Sbjct: 484 LNNYLQGWRKTLLIVSHDQGFLDDVCTDI 512
>sp|Q6P542|ABCF1_MOUSE ATP-binding cassette sub-family F member 1
Length = 837
Score = 187 bits (476), Expect = 2e-47
Identities = 106/297 (35%), Positives = 180/297 (60%), Gaps = 10/297 (3%)
Frame = +2
Query: 2 KKLVYYGGNYDQYIMTKMELEENQMKKYKWEQDQMAHMKDYIARFGHGSRKLARQAQS-- 175
++L YY GNY + + ++ +K+Y+ ++ ++ +K G +++ +Q +
Sbjct: 516 QRLHYYRGNYMTFKKMYQQKQKELLKQYEKQEKKLKELK----AGGKSTKQAEKQTKEVL 571
Query: 176 ---KEKTLKKMVDGGLTQ-----KVIREKNLVFSFPSCGEIPPPVIQVQNVSFKYGANKP 331
++K +K D + K +E + F+FP + PPV+ + V+F Y KP
Sbjct: 572 TRKQQKCRRKNQDEESQEPPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYEGQKP 631
Query: 332 LIYDNIDFGVDLDTRVALVGPNGAGKSTLLKLIASELEPTDGLIRRHSKCRIGRYHQHLH 511
L + N+DFG+D+D+R+ +VGPNG GKSTLL L+ +L PT+G +R++ + +IG ++Q
Sbjct: 632 L-FKNLDFGIDMDSRICIVGPNGVGKSTLLLLLTGKLTPTNGEMRKNHRLKIGFFNQQYA 690
Query: 512 EILDLNSTALEWMMKSFPHIKEKDEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWL 691
E L + T E++ +SF ++ +D RK LGR+GL I LS GQ+ R++FA L
Sbjct: 691 EQLHMEETPTEYLQRSF-NLPYQDA-RKCLGRFGLESHAHTIQICKLSGGQKARVVFAEL 748
Query: 692 AEGCPHMLLLDEPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCD 862
A P +L+LDEPTN+LD+E+ID+L +AIN+++G +++VSHD RLI ++WV +
Sbjct: 749 ACREPDVLILDEPTNNLDIESIDALGEAINDYKGAVIVVSHDARLITETNCQLWVVE 805
Score = 70.9 bits (172), Expect = 4e-12
Identities = 72/269 (26%), Positives = 115/269 (42%), Gaps = 38/269 (14%)
Frame = +2
Query: 158 ARQAQSKEKTLKKMVDGGLTQKVIREKNLV---FSFPSCGEIPPPVIQVQNVS------F 310
A ++ ++K LKK +D + ++ N FS S E+ ++N S F
Sbjct: 243 ANLSKKEKKKLKKQMDYERQVESLKAANAAENDFSV-SQAEVSSRQAMLENASDIKLEKF 301
Query: 311 KYGANKPLIYDNIDFGVDLDTRVALVGPNGAGKSTLLK---------------------L 427
A+ ++ N D + R LVGPNG GK+TLLK +
Sbjct: 302 SISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQEV 361
Query: 428 IASELEPTDGLIRRHSK-CRIGRYHQHLHEILDL-NSTALEWMMKSFPHIKE------KD 583
+A E ++R +K R+ + L L+ + TA E + K + ++ +
Sbjct: 362 VADETPAVQAVLRADTKRLRLLEEERRLQGQLEQGDDTAAEKLEKVYEELRATGAAAAEA 421
Query: 584 EMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETIDS 763
+ R+ L G Q P + S G R R+ A P +L+LDEPTNHLDL +
Sbjct: 422 KARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIW 481
Query: 764 LADAINEFEGGLLLVSHDFRLIGRVAEEI 850
L + + + LL+VSHD + V +I
Sbjct: 482 LNNYLQGWRKTLLIVSHDQGFLDDVCTDI 510
>sp|Q8NE71|ABCF1_HUMAN ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50)
(TNF-alpha-stimulated ABC protein)
Length = 845
Score = 186 bits (472), Expect = 7e-47
Identities = 106/297 (35%), Positives = 178/297 (59%), Gaps = 10/297 (3%)
Frame = +2
Query: 2 KKLVYYGGNYDQYIMTKMELEENQMKKYKWEQDQMAHMKDYIARFGHGSRKLARQAQS-- 175
++L YY GNY + + ++ +K+Y+ ++ ++ +K G +++ +Q +
Sbjct: 524 QRLHYYRGNYMTFKKMYQQKQKELLKQYEKQEKKLKELK----AGGKSTKQAEKQTKEAL 579
Query: 176 ---KEKTLKKMVDGGLTQ-----KVIREKNLVFSFPSCGEIPPPVIQVQNVSFKYGANKP 331
++K +K D + K +E + F+FP + PPV+ + V+F Y KP
Sbjct: 580 TRKQQKCRRKNQDEESQEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKP 639
Query: 332 LIYDNIDFGVDLDTRVALVGPNGAGKSTLLKLIASELEPTDGLIRRHSKCRIGRYHQHLH 511
L + N+DFG+D+D+R+ +VGPNG GKSTLL L+ +L PT G +R++ + +IG ++Q
Sbjct: 640 L-FKNLDFGIDMDSRICIVGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYA 698
Query: 512 EILDLNSTALEWMMKSFPHIKEKDEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWL 691
E L + T E++ + F ++ +D RK LGR+GL I LS GQ+ R++FA L
Sbjct: 699 EQLRMEETPTEYLQRGF-NLPYQDA-RKCLGRFGLESHAHTIQICKLSGGQKARVVFAEL 756
Query: 692 AEGCPHMLLLDEPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCD 862
A P +L+LDEPTN+LD+E+ID+L +AINE++G +++VSHD RLI ++WV +
Sbjct: 757 ACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVE 813
Score = 66.6 bits (161), Expect = 8e-11
Identities = 58/210 (27%), Positives = 91/210 (43%), Gaps = 29/210 (13%)
Frame = +2
Query: 308 FKYGANKPLIYDNIDFGVDLDTRVALVGPNGAGKSTLLK--------------------- 424
F A+ ++ N D + R LVGPNG GK+TLLK
Sbjct: 309 FSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQE 368
Query: 425 LIASELEPTDGLIRRHSK-CRIGRYHQHLHEILDL-NSTALEWMMKSFPHIKE------K 580
++A E ++R +K ++ + L L+ + TA E + K + ++ +
Sbjct: 369 VVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKVYEELRATGAAAAE 428
Query: 581 DEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETID 760
+ R+ L G Q P + S G R R+ A P +L+LDEPTNHLDL +
Sbjct: 429 AKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVI 488
Query: 761 SLADAINEFEGGLLLVSHDFRLIGRVAEEI 850
L + + + LL+VSHD + V +I
Sbjct: 489 WLNNYLQGWRKTLLIVSHDQGFLDDVCTDI 518
>sp|Q7YR37|ABCF1_PANTR ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50)
Length = 807
Score = 186 bits (472), Expect = 7e-47
Identities = 106/297 (35%), Positives = 178/297 (59%), Gaps = 10/297 (3%)
Frame = +2
Query: 2 KKLVYYGGNYDQYIMTKMELEENQMKKYKWEQDQMAHMKDYIARFGHGSRKLARQAQS-- 175
++L YY GNY + + ++ +K+Y+ ++ ++ +K G +++ +Q +
Sbjct: 486 QRLHYYRGNYMTFKKMYQQKQKELLKQYEKQEKKLKELK----AGGKSTKQAEKQTKEAL 541
Query: 176 ---KEKTLKKMVDGGLTQ-----KVIREKNLVFSFPSCGEIPPPVIQVQNVSFKYGANKP 331
++K +K D + K +E + F+FP + PPV+ + V+F Y KP
Sbjct: 542 TRKQQKCRRKNQDEESQEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYEGQKP 601
Query: 332 LIYDNIDFGVDLDTRVALVGPNGAGKSTLLKLIASELEPTDGLIRRHSKCRIGRYHQHLH 511
L + N+DFG+D+D+R+ +VGPNG GKSTLL L+ +L PT G +R++ + +IG ++Q
Sbjct: 602 L-FKNLDFGIDMDSRICIVGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYA 660
Query: 512 EILDLNSTALEWMMKSFPHIKEKDEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWL 691
E L + T E++ + F ++ +D RK LGR+GL I LS GQ+ R++FA L
Sbjct: 661 EQLRMEETPTEYLQRGF-NLPYQDA-RKCLGRFGLESHAHTIQICKLSGGQKARVVFAEL 718
Query: 692 AEGCPHMLLLDEPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCD 862
A P +L+LDEPTN+LD+E+ID+L +AINE++G +++VSHD RLI ++WV +
Sbjct: 719 ACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVE 775
Score = 67.0 bits (162), Expect = 6e-11
Identities = 58/210 (27%), Positives = 91/210 (43%), Gaps = 29/210 (13%)
Frame = +2
Query: 308 FKYGANKPLIYDNIDFGVDLDTRVALVGPNGAGKSTLLK--------------------- 424
F A+ ++ N D + R LVGPNG GK+TLLK
Sbjct: 271 FSISAHGKELFVNADLYIVASRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQE 330
Query: 425 LIASELEPTDGLIRRHSK-CRIGRYHQHLHEILDL-NSTALEWMMKSFPHIKE------K 580
++A E ++R +K ++ + L L+ + TA E + K + ++ +
Sbjct: 331 VVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKVYEELRATGAAAAE 390
Query: 581 DEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETID 760
+ R+ L G Q P + S G R R+ A P +L+LDEPTNHLDL +
Sbjct: 391 AKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVI 450
Query: 761 SLADAINEFEGGLLLVSHDFRLIGRVAEEI 850
L + + + LL+VSHD + V +I
Sbjct: 451 WLNNYLQGWRKTLLIVSHDQGFLDDVCTDI 480
>sp|Q767L0|ABCF1_PIG ATP-binding cassette sub-family F member 1
Length = 807
Score = 186 bits (471), Expect = 9e-47
Identities = 106/297 (35%), Positives = 178/297 (59%), Gaps = 10/297 (3%)
Frame = +2
Query: 2 KKLVYYGGNYDQYIMTKMELEENQMKKYKWEQDQMAHMKDYIARFGHGSRKLARQAQS-- 175
++L YY GNY + + ++ +K+Y+ ++ ++ +K G +++ +Q +
Sbjct: 486 QRLHYYRGNYMTFKKMYQQKQKELLKQYEKQEKKLKELK----AGGKSTKQAEKQTKEAL 541
Query: 176 ---KEKTLKKMVDGGLTQ-----KVIREKNLVFSFPSCGEIPPPVIQVQNVSFKYGANKP 331
++K +K D + K +E + F+FP + PPV+ + V+F Y KP
Sbjct: 542 TRKQQKCRRKNQDEESQEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYEGQKP 601
Query: 332 LIYDNIDFGVDLDTRVALVGPNGAGKSTLLKLIASELEPTDGLIRRHSKCRIGRYHQHLH 511
L + N+DFG+D+D+R+ +VGPNG GKSTLL L+ +L PT G +R++ + +IG ++Q
Sbjct: 602 L-FKNLDFGIDMDSRICIVGPNGVGKSTLLLLLTGKLTPTRGEMRKNHRLKIGFFNQQYA 660
Query: 512 EILDLNSTALEWMMKSFPHIKEKDEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWL 691
E L + T E++ + F ++ +D RK LGR+GL I LS GQ+ R++FA L
Sbjct: 661 EQLRMEETPTEYLQRGF-NLPYQDA-RKCLGRFGLESHAHTIQICKLSGGQKARVVFAEL 718
Query: 692 AEGCPHMLLLDEPTNHLDLETIDSLADAINEFEGGLLLVSHDFRLIGRVAEEIWVCD 862
A P +L+LDEPTN+LD+E+ID+L +AINE++G +++VSHD RLI ++WV +
Sbjct: 719 ACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVE 775
Score = 65.5 bits (158), Expect = 2e-10
Identities = 57/210 (27%), Positives = 91/210 (43%), Gaps = 29/210 (13%)
Frame = +2
Query: 308 FKYGANKPLIYDNIDFGVDLDTRVALVGPNGAGKSTLLK--------------------- 424
F A+ ++ N D + R LVGPNG GK+TLLK
Sbjct: 271 FSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQE 330
Query: 425 LIASELEPTDGLIRRHSK-CRIGRYHQHLHEILDL-NSTALEWMMKSFPHIKE------K 580
++A E ++R +K ++ + L L+ + TA + + K + ++ +
Sbjct: 331 VVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAADRLEKVYEELRATGAAAAE 390
Query: 581 DEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETID 760
+ R+ L G Q P + S G R R+ A P +L+LDEPTNHLDL +
Sbjct: 391 AKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVI 450
Query: 761 SLADAINEFEGGLLLVSHDFRLIGRVAEEI 850
L + + + LL+VSHD + V +I
Sbjct: 451 WLNNYLQGWRKTLLIVSHDQGFLDDVCTDI 480
>sp|P63390|YHES_ECO57 Hypothetical ABC transporter ATP-binding protein yheS
sp|P63389|YHES_ECOLI Hypothetical ABC transporter ATP-binding protein yheS
Length = 637
Score = 159 bits (402), Expect = 9e-39
Identities = 95/280 (33%), Positives = 160/280 (57%)
Frame = +2
Query: 17 YGGNYDQYIMTKMELEENQMKKYKWEQDQMAHMKDYIARFGHGSRKLARQAQSKEKTLKK 196
Y GNY + + + Q Y+ +Q+++AH++ YI RF + K A+QAQS+ K L++
Sbjct: 227 YTGNYSSFEVQRATRLAQQQAMYESQQERVAHLQSYIDRFRAKATK-AKQAQSRIKMLER 285
Query: 197 MVDGGLTQKVIREKNLVFSFPSCGEIPPPVIQVQNVSFKYGANKPLIYDNIDFGVDLDTR 376
M L + FSF + +P P+++++ VS YG +I D+I + +R
Sbjct: 286 ME---LIAPAHVDNPFRFSFRAPESLPNPLLKMEKVSAGYGDR--IILDSIKLNLVPGSR 340
Query: 377 VALVGPNGAGKSTLLKLIASELEPTDGLIRRHSKCRIGRYHQHLHEILDLNSTALEWMMK 556
+ L+G NGAGKSTL+KL+A EL P G I ++G + QH E L + + ++ + +
Sbjct: 341 IGLLGRNGAGKSTLIKLLAGELAPVSGEIGLAKGIKLGYFAQHQLEYLRADESPIQHLAR 400
Query: 557 SFPHIKEKDEMRKKLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTN 736
P E+ ++R LG +G G + + S G++ R++ A + P++LLLDEPTN
Sbjct: 401 LAPQELEQ-KLRDYLGGFGFQGDKVTEETRRFSGGEKARLVLALIVWQRPNLLLLDEPTN 459
Query: 737 HLDLETIDSLADAINEFEGGLLLVSHDFRLIGRVAEEIWV 856
HLDL+ +L +A+ EFEG L++VSHD L+ +++++
Sbjct: 460 HLDLDMRQALTEALIEFEGALVVVSHDRHLLRSTTDDLYL 499
Score = 64.3 bits (155), Expect = 4e-10
Identities = 52/205 (25%), Positives = 84/205 (40%), Gaps = 32/205 (15%)
Frame = +2
Query: 332 LIYDNIDFGVDLDTRVALVGPNGAGKSTLLKLIASELEPTDGLIRRHSKCRIGRYHQHLH 511
++ DN ++ +V LVG NG GKSTLL L+ +E+ G ++ +Q
Sbjct: 15 VLLDNATATINPGQKVGLVGKNGCGKSTLLALLKNEISADGGSYTFPGSWQLAWVNQ--- 71
Query: 512 EILDLNSTALEWMMKSFPHIKE--------------------------------KDEMRK 595
E L ALE+++ ++ +
Sbjct: 72 ETPALPQAALEYVIDGDREYRQLEAQLHDANERNDGHAIATIHGKLDAIDAWSIRSRAAS 131
Query: 596 KLGRYGLTGGQQICPIKSLSDGQRCRIIFAWLAEGCPHMLLLDEPTNHLDLETIDSLADA 775
L G + Q P+ S G R R+ A +LLLDEPTNHLDL+ + L
Sbjct: 132 LLHGLGFSNEQLERPVSDFSGGWRMRLNLAQALICRSDLLLLDEPTNHLDLDAVIWLEKW 191
Query: 776 INEFEGGLLLVSHDFRLIGRVAEEI 850
+ ++G L+L+SHD + + ++I
Sbjct: 192 LKSYQGTLILISHDRDFLDPIVDKI 216
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 96,595,028
Number of Sequences: 369166
Number of extensions: 1973183
Number of successful extensions: 10867
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 8992
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10372
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8550075140
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)