Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_020_I01
(830 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9Y5Y2|NUBP2_HUMAN Nucleotide binding protein 2 (NBP 2) 222 9e-58
sp|Q9R060|NUBP1_MOUSE Nucleotide-binding protein 1 (NBP 1) 218 1e-56
sp|Q9R061|NUBP2_MOUSE Nucleotide binding protein 2 (NBP 2) 213 4e-55
sp|P53384|NUBP1_HUMAN Nucleotide-binding protein 1 (NBP 1) 207 4e-53
sp|P40558|YIA3_YEAST Hypothetical 31.9 kDa protein in BET1-... 206 5e-53
sp|P52920|NBP35_YEAST NBP35 protein 189 8e-48
sp|Q93459|MRPL_CAEEL Mrp-family putative nucleotide-binding... 188 1e-47
sp|Q57731|Y283_METJA Hypothetical ATP-binding protein MJ0283 171 2e-42
sp|Q9V0D9|Y851_PYRAB Hypothetical ATP-binding protein PYRAB... 160 4e-39
sp|O58667|Y949_PYRHO Hypothetical ATP-binding protein PH0949 155 2e-37
>sp|Q9Y5Y2|NUBP2_HUMAN Nucleotide binding protein 2 (NBP 2)
Length = 271
Score = 222 bits (566), Expect = 9e-58
Identities = 108/262 (41%), Positives = 166/262 (63%), Gaps = 1/262 (0%)
Frame = +3
Query: 6 IGNVKQIVFXXXXXXXXXXXTVATQLALSLWRSNHSVGLLDIDLCGPSIPRMLGVENKEV 185
+ V+ I+ T++T+LAL+L + VG+LD+DLCGPSIPRMLG + + V
Sbjct: 10 LAGVRHIILVLSGKGGVGKSTISTELALALRHAGKKVGILDVDLCGPSIPRMLGAQGRAV 69
Query: 186 RKCDSSWLPVYADAGSAESSPRFAVMSIGFLLARPTDSVIWKGAKKDSMIKSLLNQVQWG 365
+CD W PV+ D + S +MS+GFLL +P ++V+W+G KK+++IK ++ V WG
Sbjct: 70 HQCDRGWAPVFLDREQSIS-----LMSVGFLLEKPDEAVVWRGPKKNALIKQFVSDVAWG 124
Query: 366 SLDFLIIDTPPGTSDEKI-TLATVIKQQHLSRFSGAILVSTPQMVALSDVRKEISFYQKI 542
LD+L++DTPPGTSDE + T+ + Q L GA++V+TPQ V++ DVR+E++F +K
Sbjct: 125 ELDYLVVDTPPGTSDEHMATIEALRPYQPL----GALVVTTPQAVSVGDVRRELTFCRKT 180
Query: 543 NLPILGLIENMSGLCCPRCGNIDRVFSTGGGEALAAARQIPFLGCLPMLPDIAASADTDH 722
L ++G++ENMSG CP C VFS GGGE LA +PFLG +P+ P + + + H
Sbjct: 181 GLRVMGIVENMSGFTCPHCTECTSVFSRGGGEELAQLAGVPFLGSVPLDPALMRTLEEGH 240
Query: 723 GFLVKSGCCPSNSAFSDLMAKI 788
F+ + P+ +A + + KI
Sbjct: 241 DFIQEFPGSPAFAALTSIAQKI 262
>sp|Q9R060|NUBP1_MOUSE Nucleotide-binding protein 1 (NBP 1)
Length = 320
Score = 218 bits (556), Expect = 1e-56
Identities = 105/227 (46%), Positives = 150/227 (66%), Gaps = 2/227 (0%)
Frame = +3
Query: 114 VGLLDIDLCGPSIPRMLGVENKEVRKCDSSWLPVYADAGSAESSPRFAVMSIGFLLARPT 293
V LLDID+CGPSIP+++G+E ++V + S W PVY D VMS+GFLL+ P
Sbjct: 87 VALLDIDICGPSIPKIMGLEGEQVHQSGSGWSPVYVD-------DNLGVMSVGFLLSSPD 139
Query: 294 DSVIWKGAKKDSMIKSLLNQVQWGSLDFLIIDTPPGTSDEKITLATVIKQQHLSRFSGAI 473
D+VIW+G KK+ MIK L V WG +D+LI+DTPPGTSDE +++ + H+ GA+
Sbjct: 140 DAVIWRGPKKNGMIKQFLRDVDWGDVDYLIVDTPPGTSDEHLSVVQYLAAAHI---DGAV 196
Query: 474 LVSTPQMVALSDVRKEISFYQKINLPILGLIENMSGLCCPRCGNIDRVF--STGGGEALA 647
+++TPQ VAL DVRKEISF K+ LPI+G++ENMSG CP+C ++F +TGG EA+
Sbjct: 197 ILTTPQEVALQDVRKEISFCHKVKLPIIGVVENMSGFICPKCKKESQIFPPTTGGAEAMC 256
Query: 648 AARQIPFLGCLPMLPDIAASADTDHGFLVKSGCCPSNSAFSDLMAKI 788
+IP LG +P+ P I S D F V++ P+ +A+ ++ +I
Sbjct: 257 QDLRIPLLGKVPLDPHIGKSCDKGQSFFVEAPDSPATAAYRSIIQRI 303
>sp|Q9R061|NUBP2_MOUSE Nucleotide binding protein 2 (NBP 2)
Length = 275
Score = 213 bits (543), Expect = 4e-55
Identities = 104/257 (40%), Positives = 158/257 (61%)
Frame = +3
Query: 6 IGNVKQIVFXXXXXXXXXXXTVATQLALSLWRSNHSVGLLDIDLCGPSIPRMLGVENKEV 185
+ V+ I+ T++T+LAL+L VG+LD+DLCGPSIP ML + K V
Sbjct: 14 LAGVRHIILVLSGKGGVGKSTISTELALALRHQGKKVGILDVDLCGPSIPHMLRAQGKAV 73
Query: 186 RKCDSSWLPVYADAGSAESSPRFAVMSIGFLLARPTDSVIWKGAKKDSMIKSLLNQVQWG 365
+CD+ W+PV+ D + S +MS+GFLL P ++V+W+G KK ++IK ++ V WG
Sbjct: 74 HQCDNGWVPVFVDQEQSIS-----LMSVGFLLENPDEAVVWRGPKKHALIKQFVSDVAWG 128
Query: 366 SLDFLIIDTPPGTSDEKITLATVIKQQHLSRFSGAILVSTPQMVALSDVRKEISFYQKIN 545
LD+L++DTPPGTSDE + ++ R GA++V+TPQ V++ DVR+E++F +K
Sbjct: 129 QLDYLVVDTPPGTSDEHMATMEALRPY---RPLGALVVTTPQAVSIGDVRRELTFCKKTG 185
Query: 546 LPILGLIENMSGLCCPRCGNIDRVFSTGGGEALAAARQIPFLGCLPMLPDIAASADTDHG 725
L ++G+IENMSG CP C VFS+G GE LA +PFLG +P+ + S +
Sbjct: 186 LQVIGVIENMSGFTCPHCAECTNVFSSGSGEELARLAGVPFLGSVPLDSQLTRSLEEGRD 245
Query: 726 FLVKSGCCPSNSAFSDL 776
F+ + P ++A+S L
Sbjct: 246 FIQE---FPKSTAYSAL 259
>sp|P53384|NUBP1_HUMAN Nucleotide-binding protein 1 (NBP 1)
Length = 320
Score = 207 bits (526), Expect = 4e-53
Identities = 96/231 (41%), Positives = 149/231 (64%), Gaps = 2/231 (0%)
Frame = +3
Query: 105 NHSVGLLDIDLCGPSIPRMLGVENKEVRKCDSSWLPVYADAGSAESSPRFAVMSIGFLLA 284
N + LLDID+CGPSIP+++G+E ++V + S W PVY + VMS+GFLL+
Sbjct: 84 NTQIALLDIDICGPSIPKIMGLEGEQVHQSGSGWSPVYVE-------DNLGVMSVGFLLS 136
Query: 285 RPTDSVIWKGAKKDSMIKSLLNQVQWGSLDFLIIDTPPGTSDEKITLATVIKQQHLSRFS 464
P D+VIW+G KK+ MIK L V WG +D+LI+DTPPGTSDE +++ + H+
Sbjct: 137 SPDDAVIWRGPKKNGMIKQFLRDVDWGEVDYLIVDTPPGTSDEHLSVVRYLATAHI---D 193
Query: 465 GAILVSTPQMVALSDVRKEISFYQKINLPILGLIENMSGLCCPRCGNIDRVF--STGGGE 638
GA++++TPQ ++L DVRKEI+F +K+ LPI+G++ENMS CP+C ++F +TGG E
Sbjct: 194 GAVIITTPQELSLQDVRKEINFCRKVKLPIIGVVENMSPFICPKCKKESQIFPPTTGGAE 253
Query: 639 ALAAARQIPFLGCLPMLPDIAASADTDHGFLVKSGCCPSNSAFSDLMAKIE 791
+ ++P LG +P+ P I + D F + + P+ A+ ++ +I+
Sbjct: 254 LMCQDLEVPLLGRVPLDPLIGKNCDKGQSFFIDAPDSPATLAYRSIIQRIQ 304
>sp|P40558|YIA3_YEAST Hypothetical 31.9 kDa protein in BET1-PAN1 intergenic region
Length = 293
Score = 206 bits (525), Expect = 5e-53
Identities = 112/268 (41%), Positives = 161/268 (60%), Gaps = 7/268 (2%)
Frame = +3
Query: 6 IGNVKQIVFXXXXXXXXXXXTVATQLALSLWRSNHSVGLLDIDLCGPSIPRMLGVENKEV 185
+ +K I+ +V TQ AL+L VG+LDIDL GPS+PRM G+EN+ +
Sbjct: 13 LAGIKHIILILSGKGGVGKSSVTTQTALTLCSMGFKVGVLDIDLTGPSLPRMFGLENESI 72
Query: 186 RKCDSSWLPVYADAGSAESSPRFAVMSIGFLLARPTDSVIWKGAKKDSMIKSLLNQVQWG 365
+ W PV + S S +V+S+GFLL +SVIW+G KK SMIK ++ V WG
Sbjct: 73 YQGPEGWQPVKVETNSTGS---LSVISLGFLLGDRGNSVIWRGPKKTSMIKQFISDVAWG 129
Query: 366 SLDFLIIDTPPGTSDEKITLATVIKQQHLSRFSGAILVSTPQMVALSDVRKEISFYQKIN 545
LD+L+IDTPPGTSDE I++A ++ S+ G I+V+TPQ VA +DV+KEI+F +K++
Sbjct: 130 ELDYLLIDTPPGTSDEHISIAEELRY---SKPDGGIVVTTPQSVATADVKKEINFCKKVD 186
Query: 546 LPILGLIENMSGLCCPRCGNIDRVFSTGGGEALAAARQIPFLGCLP-------MLPDIAA 704
L ILG+IENMSG CP C +FS+GGG+ L+ +P+LG +P M+ + +
Sbjct: 187 LKILGIIENMSGFVCPHCAECTNIFSSGGGKRLSEQFSVPYLGNVPIDPKFVEMIENQVS 246
Query: 705 SADTDHGFLVKSGCCPSNSAFSDLMAKI 788
S T +S CP F ++M K+
Sbjct: 247 SKKTLVEMYRESSLCP---IFEEIMKKL 271
>sp|P52920|NBP35_YEAST NBP35 protein
Length = 328
Score = 189 bits (480), Expect = 8e-48
Identities = 99/219 (45%), Positives = 135/219 (61%), Gaps = 2/219 (0%)
Frame = +3
Query: 114 VGLLDIDLCGPSIPRMLGVENKEVRKCDSSWLPVYADAGSAESSPRFAVMSIGFLLARPT 293
VG +D+D+CGPS+P MLG + V + +S W PVY + A MSI ++L
Sbjct: 105 VGAMDLDICGPSLPHMLGCIKETVHESNSGWTPVYV-------TDNLATMSIQYMLPEDD 157
Query: 294 DSVIWKGAKKDSMIKSLLNQVQWGSLDFLIIDTPPGTSDEKITLATVIKQQHLSRFSGAI 473
++IW+G+KK+ +IK L V W LD+L+IDTPPGTSDE I++ +++ S GA+
Sbjct: 158 SAIIWRGSKKNLLIKKFLKDVDWDKLDYLVIDTPPGTSDEHISINKYMRE---SGIDGAL 214
Query: 474 LVSTPQMVALSDVRKEISFYQKINLPILGLIENMSGLCCPRCGNIDRVF--STGGGEALA 647
+V+TPQ VAL DVRKEI F +K + ILGL+ENMSG CP C ++F +TGGGEAL
Sbjct: 215 VVTTPQEVALLDVRKEIDFCKKAGINILGLVENMSGFVCPNCKGESQIFKATTGGGEALC 274
Query: 648 AARQIPFLGCLPMLPDIAASADTDHGFLVKSGCCPSNSA 764
I FLG +P+ P I S D FL P++SA
Sbjct: 275 KELGIKFLGSVPLDPRIGKSCDMGESFLDNYPDSPASSA 313
>sp|Q93459|MRPL_CAEEL Mrp-family putative nucleotide-binding protein F10G8.6
Length = 313
Score = 188 bits (478), Expect = 1e-47
Identities = 103/245 (42%), Positives = 142/245 (57%), Gaps = 3/245 (1%)
Frame = +3
Query: 66 TVATQLALSLWRS-NHSVGLLDIDLCGPSIPRMLGVENKEVRKCDSSWLPVYADAGSAES 242
T+ + LA +L + V +LD+D+CGPS PRM+GVE++EV W PV
Sbjct: 74 TLTSNLARALASDPSKQVAILDVDICGPSQPRMMGVEDEEVHNSADGWTPVGIQ------ 127
Query: 243 SPRFAVMSIGFLLARPTDSVIWKGAKKDSMIKSLLNQVQWGSLDFLIIDTPPGTSDEKIT 422
P +MSI FLL D+VIW+GA+K+ MIK L V WG +D+L+IDTPPGTSDE I+
Sbjct: 128 -PNLTLMSIAFLLGDKNDAVIWRGARKNGMIKQFLKDVDWGEVDYLLIDTPPGTSDEHIS 186
Query: 423 LATVIKQQHLSRFSGAILVSTPQMVALSDVRKEISFYQKINLPILGLIENMSGLCCPRCG 602
L + Q GA++VSTPQ V+L DVRKE+SF K +PILG++ENM+ CP C
Sbjct: 187 LVQFLLQ--AGPLDGALIVSTPQEVSLLDVRKEVSFCVKTKVPILGVVENMARFVCPNCA 244
Query: 603 NIDRVF--STGGGEALAAARQIPFLGCLPMLPDIAASADTDHGFLVKSGCCPSNSAFSDL 776
+ +F STGG E + + L LP+ P +A + D F + +F DL
Sbjct: 245 HTTLLFPTSTGGAEQMCKDSNLELLAQLPLEPALAKALDNGEDFFETNPDSTLAKSFLDL 304
Query: 777 MAKIE 791
K++
Sbjct: 305 AEKVK 309
>sp|Q57731|Y283_METJA Hypothetical ATP-binding protein MJ0283
Length = 290
Score = 171 bits (433), Expect = 2e-42
Identities = 94/241 (39%), Positives = 135/241 (56%)
Frame = +3
Query: 66 TVATQLALSLWRSNHSVGLLDIDLCGPSIPRMLGVENKEVRKCDSSWLPVYADAGSAESS 245
TV LA +L VG+LD D+ GP+IP+MLGVEN + + P+ G
Sbjct: 55 TVTVNLAAALNLMGKKVGVLDADIHGPNIPKMLGVENTQPMAGPAGIFPIVTKDG----- 109
Query: 246 PRFAVMSIGFLLARPTDSVIWKGAKKDSMIKSLLNQVQWGSLDFLIIDTPPGTSDEKITL 425
MSIG+LL VIW+G K I+ L+ V WG LD+L+IDTPPGT DE++T+
Sbjct: 110 --IKTMSIGYLLPDDKTPVIWRGPKVSGAIRQFLSDVVWGELDYLLIDTPPGTGDEQLTI 167
Query: 426 ATVIKQQHLSRFSGAILVSTPQMVALSDVRKEISFYQKINLPILGLIENMSGLCCPRCGN 605
Q + GAI+V+TP+ V++ DV+K I + +N+PI+G+IENMSG CP C
Sbjct: 168 -----MQSIPDIDGAIIVTTPEEVSVLDVKKSIMMAKMLNIPIIGIIENMSGFVCPYCNK 222
Query: 606 IDRVFSTGGGEALAAARQIPFLGCLPMLPDIAASADTDHGFLVKSGCCPSNSAFSDLMAK 785
+ +F GGGE A + FLG +P+ DI A +D G + C ++ F ++ +
Sbjct: 223 VVDIFGRGGGEKAAKELGVEFLGRIPL--DIKAREASDKGIPMVLLDCKASEEFKKIVKR 280
Query: 786 I 788
I
Sbjct: 281 I 281
>sp|Q9V0D9|Y851_PYRAB Hypothetical ATP-binding protein PYRAB08510
Length = 295
Score = 160 bits (405), Expect = 4e-39
Identities = 100/248 (40%), Positives = 144/248 (58%), Gaps = 7/248 (2%)
Frame = +3
Query: 66 TVATQLALSLWRSNHSVGLLDIDLCGPSIPRMLGVENKEV--RKCDSS---WLPVYADAG 230
TVA L +L + + VG+LD D+ GP++ +MLGVE +E+ K D +P AD
Sbjct: 46 TVAVNLTAALAKMGYFVGILDADIHGPNVAKMLGVEKEEIYAEKFDDGHFEMIPPMADF- 104
Query: 231 SAESSPRFAVMSIGFLLARPTDS-VIWKGAKKDSMIKSLLNQVQWGSLDFLIIDTPPGTS 407
+ +P VMS+G ++ P D +IW+GA IK LL V+WGSLDF+IID PPGT
Sbjct: 105 MGQVTP-IKVMSMGMMV--PEDQPIIWRGALVTKAIKQLLGDVKWGSLDFMIIDFPPGTG 161
Query: 408 DEKITLATVIKQQHLSRFSGAILVSTPQMVALSDVRKEISFYQKINLPILGLIENMSGLC 587
DE +T+ I+ AI+V+TPQ VAL D K ++ +K+ +P + ++ENMS L
Sbjct: 162 DEILTVVQSIQ------LDAAIIVTTPQEVALLDTGKAVNMMKKMEVPYIAVVENMSYLI 215
Query: 588 CPRCGNIDRVFSTGGGEALAAARQIPFLGCLPMLPDIAASADTDHGF-LVKSGCCPSNSA 764
CP CGN +F GGGE LA + FLG +P+ D+ A +D G +V G P+ A
Sbjct: 216 CPHCGNKIDIFGEGGGEKLAEKEGVDFLGKIPI--DLKAREASDLGIPIVLYGDTPAAKA 273
Query: 765 FSDLMAKI 788
F ++ K+
Sbjct: 274 FMEIAEKL 281
>sp|O58667|Y949_PYRHO Hypothetical ATP-binding protein PH0949
Length = 295
Score = 155 bits (391), Expect = 2e-37
Identities = 100/248 (40%), Positives = 141/248 (56%), Gaps = 7/248 (2%)
Frame = +3
Query: 66 TVATQLALSLWRSNHSVGLLDIDLCGPSIPRMLGVENKEV--RKCDSS---WLPVYADAG 230
TVA L +L + + VG+LD D+ GP++ +MLGV+ +EV K D +P D
Sbjct: 46 TVAVNLTAALAKMGYFVGILDADIHGPNVAKMLGVDKEEVYAEKFDDGHFEMIPPTTDF- 104
Query: 231 SAESSPRFAVMSIGFLLARPTDS-VIWKGAKKDSMIKSLLNQVQWGSLDFLIIDTPPGTS 407
+ +P VMS+G ++ P D VIW+G IK LL V+WGSLDF+IID PPGT
Sbjct: 105 MGQVTP-IKVMSMGMMV--PEDQPVIWRGPLVTKAIKQLLGDVKWGSLDFMIIDFPPGTG 161
Query: 408 DEKITLATVIKQQHLSRFSGAILVSTPQMVALSDVRKEISFYQKINLPILGLIENMSGLC 587
DE +T+ IK AI+V+TPQ VAL D K ++ +K+ +P + ++ENMS L
Sbjct: 162 DEILTVVQSIK------LDAAIIVTTPQEVALLDTGKAVNMMKKMEVPYVAVVENMSYLI 215
Query: 588 CPRCGNIDRVFSTGGGEALAAARQIPFLGCLPMLPDIAASADTDHGF-LVKSGCCPSNSA 764
CP CGN +F GGGE LA + FLG +P+ D+ A +D G +V P+ A
Sbjct: 216 CPHCGNKIDIFGEGGGEKLAQKEGVDFLGKIPI--DLKAREASDLGIPIVLYEDTPAAKA 273
Query: 765 FSDLMAKI 788
F +L K+
Sbjct: 274 FMELAEKL 281
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 109,968,901
Number of Sequences: 369166
Number of extensions: 2510815
Number of successful extensions: 7890
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 7349
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7823
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8052550455
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)