Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_020_H06
(718 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8WXS8|ATS14_HUMAN ADAMTS-14 precursor (A disintegrin an... 87 4e-17
sp|Q4VC17|ATS18_MOUSE ADAMTS-18 precursor (A disintegrin an... 86 1e-16
sp|Q8TE60|ATS18_HUMAN ADAMTS-18 precursor (A disintegrin an... 85 2e-16
sp|P58397|ATS12_HUMAN ADAMTS-12 precursor (A disintegrin an... 80 7e-15
sp|Q811B3|ATS12_MOUSE ADAMTS-12 precursor (A disintegrin an... 79 9e-15
sp|O95450|ATS2_HUMAN ADAMTS-2 precursor (A disintegrin and ... 79 1e-14
sp|P79331|ATS2_BOVIN ADAMTS-2 precursor (A disintegrin and ... 79 1e-14
sp|Q8C9W3|ATS2_MOUSE ADAMTS-2 precursor (A disintegrin and ... 77 4e-14
sp|Q8TE56|ATS17_HUMAN ADAMTS-17 precursor (A disintegrin an... 74 3e-13
sp|Q9H324|ATS10_HUMAN ADAMTS-10 precursor (A disintegrin an... 73 9e-13
>sp|Q8WXS8|ATS14_HUMAN ADAMTS-14 precursor (A disintegrin and metalloproteinase with
thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14)
Length = 1223
Score = 87.0 bits (214), Expect = 4e-17
Identities = 56/189 (29%), Positives = 87/189 (46%), Gaps = 5/189 (2%)
Frame = +3
Query: 42 SMLIFNLIISVTIITISG---FLTFGKSTYVWSPIDEWSPCSKPCGVGVETQTFVCLKKT 212
S L + +I ++ + G L TY W+ + W+PCSK CG G++ + C ++
Sbjct: 820 SSLAYKYVIHEDLLPLIGSNNVLLEEMDTYEWA-LKSWAPCSKACGGGIQFTKYGCRRR- 877
Query: 213 RYRTLEYTEKPKCPLSTRPNQTRNCSLGDCQNDSFGSYVWQVGNWSACPKNCGGNGLQNR 392
R ++ C RP R C VW W AC ++CG G+Q R
Sbjct: 878 --RDHHMVQRHLCDHKKRPKPIRR----RCNQHPCSQPVWVTEEWGACSRSCGKLGVQTR 931
Query: 393 DVNCFLMTSKG--QFLPAKLSKCNYKLEPRRYISCGQIDCPPKFLASKWGKCQESATCQP 566
+ C L S G + +PAK + + E RR C ++ CP ++ W +C SATC
Sbjct: 932 GIQCLLPLSNGTHKVMPAK-ACAGDRPEARR--PCLRVPCPAQWRLGAWSQC--SATCGE 986
Query: 567 VVRQREVKC 593
++QR+V C
Sbjct: 987 GIQQRQVVC 995
>sp|Q4VC17|ATS18_MOUSE ADAMTS-18 precursor (A disintegrin and metalloproteinase with
thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18)
Length = 1219
Score = 85.9 bits (211), Expect = 1e-16
Identities = 58/169 (34%), Positives = 81/169 (47%), Gaps = 4/169 (2%)
Frame = +3
Query: 126 WSPIDEWSPCSKPCGVGVETQTFVCLKKTRYRTLEYTEKPKCPLSTRPNQTRNCSLGDCQ 305
W P EWS CSK C G +++ C++K ++ E CP+ST P Q + C+ C
Sbjct: 935 WLP-GEWSACSKSCAGGQQSRKIRCVQKKPFQKEEAVLHSLCPVST-PTQVQVCNSHACP 992
Query: 306 NDSFGSYVWQVGNWSACPKNCGGNGLQNRDVNCFLMTSKGQFLPAKLSKCNYKLEPRRYI 485
+ W WS C K C G G++ R+V C + + LP L C+ P
Sbjct: 993 PE------WSPSPWSQCSKTC-GRGVRRREVLC--KSPAAETLPESL--CSSSPRPEAQE 1041
Query: 486 SCGQIDCPP----KFLASKWGKCQESATCQPVVRQREVKCVSLLSTGKL 620
C CP +++AS W +C SATC VR+RE+KCV GKL
Sbjct: 1042 GCVLGRCPKNNRLQWIASAWSEC--SATCGLGVRKRELKCVEKTLQGKL 1088
Score = 51.2 bits (121), Expect = 3e-06
Identities = 36/124 (29%), Positives = 50/124 (40%), Gaps = 2/124 (1%)
Frame = +3
Query: 144 WSPCSKPCGVGVETQTFVCLKKTRYRTLEYTEKPKCPLSTRPN--QTRNCSLGDCQNDSF 317
WS CS CG+GV + C++KT L + +C +P+ C+ C S
Sbjct: 1061 WSECSATCGLGVRKRELKCVEKTLQGKLITFPERRCRNIKKPSLELEEACNQRTCPVYSM 1120
Query: 318 GSYVWQVGNWSACPKNCGGNGLQNRDVNCFLMTSKGQFLPAKLSKCNYKLEPRRYISCGQ 497
W W C CGG G+Q R V+C Q P+ S C +P +C
Sbjct: 1121 AVASWYSSPWQQCTVTCGG-GVQTRSVHCM-----QQGRPS--SSCLLHQKPPVLRACNT 1172
Query: 498 IDCP 509
CP
Sbjct: 1173 NFCP 1176
Score = 33.5 bits (75), Expect = 0.58
Identities = 22/78 (28%), Positives = 33/78 (42%)
Frame = +3
Query: 126 WSPIDEWSPCSKPCGVGVETQTFVCLKKTRYRTLEYTEKPKCPLSTRPNQTRNCSLGDCQ 305
WS +WS CS+ CG GV+ Q C +Y CP S+R + C++ C
Sbjct: 592 WSAWSKWSECSRTCGGGVKFQERHCSNPKPQYGGKY-----CPGSSRIYKL--CNINPCP 644
Query: 306 NDSFGSYVWQVGNWSACP 359
+S Q ++ P
Sbjct: 645 ENSLDFRAQQCAEYNNKP 662
Score = 33.1 bits (74), Expect = 0.76
Identities = 21/84 (25%), Positives = 35/84 (41%), Gaps = 1/84 (1%)
Frame = +3
Query: 348 SACPKNCGGNGLQNRDVNCFLMTSKGQFLPAKLSKCNYKLEPRRYIS-CGQIDCPPKFLA 524
S C CGG + + + C + Q S C+ + +P C CP +L
Sbjct: 883 SDCSVTCGGGYISIKAI-CL----RDQHTQVNSSFCSVRTKPATEPKICNAFSCPAYWLP 937
Query: 525 SKWGKCQESATCQPVVRQREVKCV 596
+W C +S C + R+++CV
Sbjct: 938 GEWSACSKS--CAGGQQSRKIRCV 959
>sp|Q8TE60|ATS18_HUMAN ADAMTS-18 precursor (A disintegrin and metalloproteinase with
thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18)
Length = 1221
Score = 84.7 bits (208), Expect = 2e-16
Identities = 58/169 (34%), Positives = 81/169 (47%), Gaps = 4/169 (2%)
Frame = +3
Query: 126 WSPIDEWSPCSKPCGVGVETQTFVCLKKTRYRTLEYTEKPKCPLSTRPNQTRNCSLGDCQ 305
W P EWS CSK C G +++ C++K ++ E CP+ST P Q + C+ C
Sbjct: 935 WMP-GEWSTCSKACAGGQQSRKIQCVQKKPFQKEEAVLHSLCPVST-PTQVQACNSHACP 992
Query: 306 NDSFGSYVWQVGNWSACPKNCGGNGLQNRDVNCFLMTSKGQFLPAKLSKCNYKLEPRRYI 485
W +G WS C K C G G++ R++ C S + LP S+C P
Sbjct: 993 PQ------WSLGPWSQCSKTC-GRGVRKRELLC--KGSAAETLPE--SQCTSLPRPELQE 1041
Query: 486 SCGQIDCPP----KFLASKWGKCQESATCQPVVRQREVKCVSLLSTGKL 620
C CP +++AS W +C SATC VR+RE+KC GKL
Sbjct: 1042 GCVLGRCPKNSRLQWVASSWSEC--SATCGLGVRKREMKCSEKGFQGKL 1088
Score = 43.9 bits (102), Expect = 4e-04
Identities = 28/91 (30%), Positives = 38/91 (41%), Gaps = 4/91 (4%)
Frame = +3
Query: 144 WSPCSKPCGVGVETQTFVCLKKTRYRTLEYTEKPKCPLSTRPN--QTRNCSLGDCQNDSF 317
WS CS CG+GV + C +K L + +C +PN C+ C
Sbjct: 1061 WSECSATCGLGVRKREMKCSEKGFQGKLITFPERRCRNIKKPNLDLEETCNRRACPAHPV 1120
Query: 318 GSYV--WQVGNWSACPKNCGGNGLQNRDVNC 404
+ V W W C CGG G+Q R V+C
Sbjct: 1121 YNMVAGWYSLPWQQCTVTCGG-GVQTRSVHC 1150
Score = 35.8 bits (81), Expect = 0.12
Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 1/79 (1%)
Frame = +3
Query: 126 WSPIDEWSPCSKPCGVGVETQTFVCLK-KTRYRTLEYTEKPKCPLSTRPNQTRNCSLGDC 302
WS +WS CS+ CG GV+ Q C K +Y + CP S+R Q C++ C
Sbjct: 592 WSAWSKWSECSRTCGGGVKFQERHCNNPKPQYGGI------FCPGSSRIYQL--CNINPC 643
Query: 303 QNDSFGSYVWQVGNWSACP 359
+S Q +++ P
Sbjct: 644 NENSLDFRAQQCAEYNSKP 662
Score = 34.7 bits (78), Expect = 0.26
Identities = 23/93 (24%), Positives = 38/93 (40%), Gaps = 1/93 (1%)
Frame = +3
Query: 321 SYVWQVGNWSACPKNCGGNGLQNRDVNCFLMTSKGQFLPAKLSKCNYKLEPRRYIS-CGQ 497
+Y W + S C +CGG +N + + Q S C+ K +P C
Sbjct: 875 AYTWSIVQ-SECSVSCGGGY-----INVKAICLRDQNTQVNSSFCSAKTKPVTEPKICNA 928
Query: 498 IDCPPKFLASKWGKCQESATCQPVVRQREVKCV 596
CP ++ +W C S C + R+++CV
Sbjct: 929 FSCPAYWMPGEWSTC--SKACAGGQQSRKIQCV 959
Score = 31.2 bits (69), Expect = 2.9
Identities = 15/53 (28%), Positives = 24/53 (45%)
Frame = +3
Query: 144 WSPCSKPCGVGVETQTFVCLKKTRYRTLEYTEKPKCPLSTRPNQTRNCSLGDC 302
W C+ CG GV+T++ C+++ R C L +P R C+ C
Sbjct: 1132 WQQCTVTCGGGVQTRSVHCVQQGR-------PSSSCLLHQKPPVLRACNTNFC 1177
>sp|P58397|ATS12_HUMAN ADAMTS-12 precursor (A disintegrin and metalloproteinase with
thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12)
Length = 1593
Score = 79.7 bits (195), Expect = 7e-15
Identities = 53/161 (32%), Positives = 71/161 (44%), Gaps = 3/161 (1%)
Frame = +3
Query: 120 YVWSPIDEWSPCSKPCGVGVETQTFVCLKKTRYRTLEYTEKPKCPLSTRPN-QTRNCSLG 296
Y W W+ CS CG G+ QT C+KK R + C T+PN + + C
Sbjct: 825 YFWQ-YGHWTECSVTCGTGIRRQTAHCIKKGR----GMVKATFCDPETQPNGRQKKCHEK 879
Query: 297 DCQNDSFGSYVWQVGNWSACPKNCGGNGLQNRDVNCF-LMTSKGQFLPAKLSKCNYKLEP 473
C W G W AC CG +G + R V C M S Q LP + C + L+P
Sbjct: 880 ACPPR------WWAGEWEACSATCGPHGEKKRTVLCIQTMVSDEQALPP--TDCQHLLKP 931
Query: 474 RRYISCGQ-IDCPPKFLASKWGKCQESATCQPVVRQREVKC 593
+ +SC + I CP + W +C S +C VR R V C
Sbjct: 932 KTLLSCNRDILCPSDWTVGNWSEC--SVSCGGGVRIRSVTC 970
Score = 60.1 bits (144), Expect = 6e-09
Identities = 45/167 (26%), Positives = 65/167 (38%), Gaps = 2/167 (1%)
Frame = +3
Query: 99 LTFGKSTYVWSPIDEWSPCSKPCGVGVETQTFVCLKKTRYRTLEYTEKPKCPLSTRPNQT 278
LT G + W + WS CS CG+G + C + C RP+
Sbjct: 1307 LTNGHGSAHWI-VGNWSECSTTCGLGAYWKRVECTTQM---------DSDCAAIQRPDPA 1356
Query: 279 RNCSLGDCQNDSFGSYVWQVGNWSACPKNCGGNGLQNRDVNCFLMTSKGQFLPAKLSKCN 458
+ C L C W+VGNWS C +NC G G + R++ C P C
Sbjct: 1357 KRCHLRPCAG-------WKVGNWSKCSRNCSG-GFKIREIQCVDSRDHRNLRP---FHCQ 1405
Query: 459 Y--KLEPRRYISCGQIDCPPKFLASKWGKCQESATCQPVVRQREVKC 593
+ + P +SC C + W +C S +C V++R V C
Sbjct: 1406 FLAGIPPPLSMSCNPEPC-EAWQVEPWSQC--SRSCGGGVQERGVFC 1449
Score = 55.5 bits (132), Expect = 1e-07
Identities = 33/102 (32%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +3
Query: 306 NDSFGSYVWQVGNWSACPKNCGGNGLQNRDVNCFLMTSKGQFLPAKLSKCNYKLEPR-RY 482
ND Y WQ G+W+ C C G G++ + +C KG+ + K + C+ + +P R
Sbjct: 819 NDVEQMYFWQYGHWTECSVTC-GTGIRRQTAHCI---KKGRGM-VKATFCDPETQPNGRQ 873
Query: 483 ISCGQIDCPPKFLASKWGKCQESATCQP-VVRQREVKCVSLL 605
C + CPP++ A +W C SATC P ++R V C+ +
Sbjct: 874 KKCHEKACPPRWWAGEWEAC--SATCGPHGEKKRTVLCIQTM 913
Score = 55.1 bits (131), Expect = 2e-07
Identities = 36/125 (28%), Positives = 52/125 (41%), Gaps = 1/125 (0%)
Frame = +3
Query: 135 IDEWSPCSKPCGVGVETQTFVCLKKTRYRTLEYTEKPKCPLSTRPNQTRNCSLGDCQNDS 314
++ WS CS+ CG GV+ + C C + RP T +C+ C +
Sbjct: 1428 VEPWSQCSRSCGGGVQERGVFC------------PGGLCDWTKRPTSTMSCNEHLCCH-- 1473
Query: 315 FGSYVWQVGNWSACPKNCGGNGLQNRDVNCFLMTSKGQFLPAK-LSKCNYKLEPRRYISC 491
W GNW C +CGG G Q R V C + S+G + C++K P + C
Sbjct: 1474 -----WATGNWDLCSTSCGG-GFQKRIVQC--VPSEGNKTEDQDQCLCDHKPRPPEFKKC 1525
Query: 492 GQIDC 506
Q C
Sbjct: 1526 NQQAC 1530
Score = 34.3 bits (77), Expect = 0.34
Identities = 16/56 (28%), Positives = 22/56 (39%)
Frame = +3
Query: 135 IDEWSPCSKPCGVGVETQTFVCLKKTRYRTLEYTEKPKCPLSTRPNQTRNCSLGDC 302
+ WS CS CG GV ++ C K C ++ +PN C L C
Sbjct: 949 VGNWSECSVSCGGGVRIRSVTCAK---------NHDEPCDVTRKPNSRALCGLQQC 995
Score = 30.8 bits (68), Expect = 3.8
Identities = 12/25 (48%), Positives = 16/25 (64%)
Frame = +3
Query: 126 WSPIDEWSPCSKPCGVGVETQTFVC 200
WSP WS CS+ CG GV++ +C
Sbjct: 548 WSP---WSHCSRTCGAGVQSAERLC 569
>sp|Q811B3|ATS12_MOUSE ADAMTS-12 precursor (A disintegrin and metalloproteinase with
thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12)
Length = 1600
Score = 79.3 bits (194), Expect = 9e-15
Identities = 56/178 (31%), Positives = 76/178 (42%), Gaps = 3/178 (1%)
Frame = +3
Query: 111 KSTYVWSPIDEWSPCSKPCGVGVETQTFVCLKKTRYRTLEYTEKPKCPLSTRPN-QTRNC 287
K Y W W+ CS CG G+ Q C+KK + C T+P+ + + C
Sbjct: 827 KLLYFWQ-FGRWTECSVTCGTGIRRQAAHCVKKGH----GIVKTTFCNPETQPSVRQKKC 881
Query: 288 SLGDCQNDSFGSYVWQVGNWSACPKNCGGNGLQNRDVNCF-LMTSKGQFLPAKLSKCNYK 464
DC W G W AC CG G + R V C M S Q LPA + C +
Sbjct: 882 HEKDCPPR------WWAGEWEACSTTCGPYGEKKRTVLCIQTMGSDEQALPA--TDCQHL 933
Query: 465 LEPRRYISCGQ-IDCPPKFLASKWGKCQESATCQPVVRQREVKCVSLLSTGKLKIQSP 635
L+P+ +SC + I CP + W +C S +C VR R V C L+ K + P
Sbjct: 934 LKPKALVSCNRDILCPSDWTVGNWSEC--SVSCGGGVRIRSVTCAKNLNEPCDKTRKP 989
Score = 61.6 bits (148), Expect = 2e-09
Identities = 51/165 (30%), Positives = 66/165 (40%), Gaps = 12/165 (7%)
Frame = +3
Query: 135 IDEWSPCSKPCGVGVETQTFVCLKKTRYRTLEYTEKPKCPLSTRPNQTRNCSLGDCQNDS 314
+ WS CS CG+G ++ C C RP+ + C L C
Sbjct: 1324 VGNWSKCSTTCGLGAYWRSVECSSGV---------DADCTTIQRPDPAKKCHLRPCAG-- 1372
Query: 315 FGSYVWQVGNWSACPKNCGGNGLQNRDVNCF--------LMTSKGQFL---PAKLS-KCN 458
W+VGNWS C +NC G G + R+V C L QFL P LS CN
Sbjct: 1373 -----WRVGNWSKCSRNCSG-GFKIREVQCMDSLDHHRSLRPFHCQFLAGAPPPLSMSCN 1426
Query: 459 YKLEPRRYISCGQIDCPPKFLASKWGKCQESATCQPVVRQREVKC 593
LEP CG+ P W +C S +C V++R V C
Sbjct: 1427 --LEP-----CGEWQVEP------WSQC--SRSCGGGVQERGVSC 1456
Score = 52.4 bits (124), Expect = 1e-06
Identities = 32/124 (25%), Positives = 52/124 (41%)
Frame = +3
Query: 135 IDEWSPCSKPCGVGVETQTFVCLKKTRYRTLEYTEKPKCPLSTRPNQTRNCSLGDCQNDS 314
++ WS CS+ CG GV+ + C C + RP T C+ C +
Sbjct: 1435 VEPWSQCSRSCGGGVQERGVSC------------PGGLCDWTKRPATTVPCNRHLCCH-- 1480
Query: 315 FGSYVWQVGNWSACPKNCGGNGLQNRDVNCFLMTSKGQFLPAKLSKCNYKLEPRRYISCG 494
W GNW C +CGG G Q R ++C + + C+++++P + +C
Sbjct: 1481 -----WATGNWELCNTSCGG-GSQKRTIHC-IPSENSTTEDQDQCLCDHQVKPPEFQTCN 1533
Query: 495 QIDC 506
Q C
Sbjct: 1534 QQAC 1537
Score = 50.4 bits (119), Expect = 5e-06
Identities = 33/124 (26%), Positives = 52/124 (41%), Gaps = 1/124 (0%)
Frame = +3
Query: 141 EWSPCSKPCG-VGVETQTFVCLKKTRYRTLEYTEKPKCPLSTRPNQTRNCSLGDCQNDSF 317
EW CS CG G + +T +C++ +++ P + + + +L C D
Sbjct: 894 EWEACSTTCGPYGEKKRTVLCIQTMG------SDEQALPATDCQHLLKPKALVSCNRDIL 947
Query: 318 GSYVWQVGNWSACPKNCGGNGLQNRDVNCFLMTSKGQFLPAKLSKCNYKLEPRRYISCGQ 497
W VGNWS C +CGG G++ R V C ++ C+ +P CG
Sbjct: 948 CPSDWTVGNWSECSVSCGG-GVRIRSVTCAKNLNE---------PCDKTRKPNSRALCGL 997
Query: 498 IDCP 509
CP
Sbjct: 998 QQCP 1001
Score = 33.5 bits (75), Expect = 0.58
Identities = 29/92 (31%), Positives = 34/92 (36%)
Frame = +3
Query: 330 WQVGNWSACPKNCGGNGLQNRDVNCFLMTSKGQFLPAKLSKCNYKLEPRRYISCGQIDCP 509
W VGNWS C C G G R V C S G + C P C C
Sbjct: 1322 WIVGNWSKCSTTC-GLGAYWRSVEC----SSGVD-----ADCTTIQRPDPAKKCHLRPC- 1370
Query: 510 PKFLASKWGKCQESATCQPVVRQREVKCVSLL 605
+ W KC S C + REV+C+ L
Sbjct: 1371 AGWRVGNWSKC--SRNCSGGFKIREVQCMDSL 1400
>sp|O95450|ATS2_HUMAN ADAMTS-2 precursor (A disintegrin and metalloproteinase with
thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2)
(Procollagen I/II amino propeptide-processing enzyme)
(Procollagen I N-proteinase) (PC I-NP) (Procollagen
N-endopeptidase) (pNPI)
Length = 1211
Score = 79.0 bits (193), Expect = 1e-14
Identities = 44/158 (27%), Positives = 66/158 (41%)
Frame = +3
Query: 120 YVWSPIDEWSPCSKPCGVGVETQTFVCLKKTRYRTLEYTEKPKCPLSTRPNQTRNCSLGD 299
Y W+ + +WSPCSKPCG G + + C ++ ++ + + C ++P R
Sbjct: 856 YEWA-LKKWSPCSKPCGGGSQFTKYGCRRRLDHKMVH---RGFCAALSKPKAIRRA---- 907
Query: 300 CQNDSFGSYVWQVGNWSACPKNCGGNGLQNRDVNCFLMTSKGQFLPAKLSKCNYKLEPRR 479
C VW G W C + CG G+Q R V C CN P
Sbjct: 908 CNPQECSQPVWVTGEWEPCSQTCGRTGMQVRSVRCIQPLHDNTTRSVHAKHCN-DARPES 966
Query: 480 YISCGQIDCPPKFLASKWGKCQESATCQPVVRQREVKC 593
+C + CP ++ A W +C S TC ++R V C
Sbjct: 967 RRACSRELCPGRWRAGPWSQC--SVTCGNGTQERPVPC 1002
>sp|P79331|ATS2_BOVIN ADAMTS-2 precursor (A disintegrin and metalloproteinase with
thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2)
(Procollagen I/II amino propeptide-processing enzyme)
(Procollagen I N-proteinase) (PC I-NP) (Procollagen
N-endopeptidase) (pNPI)
Length = 1205
Score = 79.0 bits (193), Expect = 1e-14
Identities = 45/159 (28%), Positives = 70/159 (44%), Gaps = 1/159 (0%)
Frame = +3
Query: 120 YVWSPIDEWSPCSKPCGVGVETQTFVCLKKTRYRTLEYTEKPKCPLSTRPNQTRN-CSLG 296
Y W+ + +WSPCSKPCG G + + C ++ ++ + + C ++P R C+
Sbjct: 850 YEWA-LKKWSPCSKPCGGGSQFTKYGCRRRLDHKMVH---RGFCDSVSKPKAIRRTCNPQ 905
Query: 297 DCQNDSFGSYVWQVGNWSACPKNCGGNGLQNRDVNCFLMTSKGQFLPAKLSKCNYKLEPR 476
+C VW G W C ++CG G+Q R V C CN P
Sbjct: 906 ECSQP-----VWVTGEWEPCSRSCGRTGMQVRSVRCVQPLHNNTTRSVHTKHCN-DARPE 959
Query: 477 RYISCGQIDCPPKFLASKWGKCQESATCQPVVRQREVKC 593
+C + CP ++ A W +C S TC ++R V C
Sbjct: 960 GRRACNRELCPGRWRAGSWSQC--SVTCGNGTQERPVLC 996
Score = 33.5 bits (75), Expect = 0.58
Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 2/103 (1%)
Frame = +3
Query: 303 QNDSFGSYVWQVGNWSACPKNCGGNGLQNRDVNCFLMTSKGQFLPAKLSKCNYKLEPRRY 482
++DS G Y W + WS C K CGG G Q C + C+ +P+
Sbjct: 844 EDDSVG-YEWALKKWSPCSKPCGG-GSQFTKYGC---RRRLDHKMVHRGFCDSVSKPKAI 898
Query: 483 -ISCGQIDC-PPKFLASKWGKCQESATCQPVVRQREVKCVSLL 605
+C +C P ++ +W C S + ++ R V+CV L
Sbjct: 899 RRTCNPQECSQPVWVTGEWEPCSRSCG-RTGMQVRSVRCVQPL 940
>sp|Q8C9W3|ATS2_MOUSE ADAMTS-2 precursor (A disintegrin and metalloproteinase with
thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2)
(Procollagen I/II amino propeptide-processing enzyme)
(Procollagen I N-proteinase) (PC I-NP) (Procollagen
N-endopeptidase) (pNPI)
Length = 1213
Score = 77.4 bits (189), Expect = 4e-14
Identities = 44/154 (28%), Positives = 66/154 (42%), Gaps = 1/154 (0%)
Frame = +3
Query: 135 IDEWSPCSKPCGVGVETQTFVCLKKTRYRTLEYTEKPKCPLSTRPNQTRNCSLGDCQNDS 314
+ +WSPCSKPCG G + + C ++ + + + C +P R C
Sbjct: 861 LKKWSPCSKPCGGGSQFTKYGCRRRLDSKMVH---RAFCSALAKPKAIRRA----CNPQE 913
Query: 315 FGSYVWQVGNWSACPKNCGGNGLQNRDVNCFLMTSKGQFLPAKLSKCN-YKLEPRRYISC 491
VW G W C ++CG G+Q R V C CN ++ E RR +C
Sbjct: 914 CSQPVWVTGEWEPCTQSCGRTGMQVRSVRCIQPLHNNTTRSVHTKHCNDHRPESRR--AC 971
Query: 492 GQIDCPPKFLASKWGKCQESATCQPVVRQREVKC 593
+ CP ++ A W +C S TC ++R V C
Sbjct: 972 NRELCPGRWRAGSWSQC--SVTCGNGTQERPVLC 1003
Score = 31.2 bits (69), Expect = 2.9
Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 1/93 (1%)
Frame = +3
Query: 330 WQVGNWSACPKNCGGNGLQNRDVNCFLMTSKGQFLPAKLSKCNYKLEPRRYISCGQIDC- 506
W + WS C K CGG G Q C A S RR +C +C
Sbjct: 859 WALKKWSPCSKPCGG-GSQFTKYGCRRRLDSKMVHRAFCSALAKPKAIRR--ACNPQECS 915
Query: 507 PPKFLASKWGKCQESATCQPVVRQREVKCVSLL 605
P ++ +W C +S + ++ R V+C+ L
Sbjct: 916 QPVWVTGEWEPCTQSCG-RTGMQVRSVRCIQPL 947
>sp|Q8TE56|ATS17_HUMAN ADAMTS-17 precursor (A disintegrin and metalloproteinase with
thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17)
Length = 1095
Score = 74.3 bits (181), Expect = 3e-13
Identities = 54/169 (31%), Positives = 74/169 (43%), Gaps = 1/169 (0%)
Frame = +3
Query: 114 STYVWSPIDEWSPCSKPCGVGVETQTFVCLKKTRYRTLEYTEKPKCPLSTRPN-QTRNCS 290
S ++W+ W CS CG G E +T V + +T CP ++RP Q R C+
Sbjct: 800 SLFIWTH-SGWEGCSVQCG-GGERRTIVSCTRIVNKTTTLVNDSDCPQASRPEPQVRRCN 857
Query: 291 LGDCQNDSFGSYVWQVGNWSACPKNCGGNGLQNRDVNCFLMTSKGQFLPAKLSKCNYKLE 470
L CQ+ W G WS C C G Q+R+V C G + + C
Sbjct: 858 LHPCQSR------WVAGPWSPCSATC-EKGFQHREVTCVYQLQNGTHVATRPLYCPGP-R 909
Query: 471 PRRYISCGQIDCPPKFLASKWGKCQESATCQPVVRQREVKCVSLLSTGK 617
P SC DC + AS+W +C SA+C V +R V C + S GK
Sbjct: 910 PAAVQSCEGQDCLSIWEASEWSQC--SASCGKGVWKRTVACTN--SQGK 954
Score = 63.9 bits (154), Expect = 4e-10
Identities = 43/135 (31%), Positives = 54/135 (40%)
Frame = +3
Query: 123 VWSPIDEWSPCSKPCGVGVETQTFVCLKKTRYRTLEYTEKPKCPLSTRPNQTRNCSLGDC 302
+W EWS CS CG GV +T C + KC STRP C
Sbjct: 924 IWEA-SEWSQCSASCGKGVWKRTVACTNS----------QGKCDASTRPRAEEACE---- 968
Query: 303 QNDSFGSYVWQVGNWSACPKNCGGNGLQNRDVNCFLMTSKGQFLPAKLSKCNYKLEPRRY 482
D G Y W+ G+WS C C G GLQ+R V C + S+C +P Y
Sbjct: 969 --DYSGCYEWKTGDWSTCSSTC-GKGLQSRVVQCMHKVTGRHG-----SECPALSKPAPY 1020
Query: 483 ISCGQIDCPPKFLAS 527
C Q C + A+
Sbjct: 1021 RQCYQEVCNDRINAN 1035
Score = 50.1 bits (118), Expect = 6e-06
Identities = 35/115 (30%), Positives = 47/115 (40%), Gaps = 1/115 (0%)
Frame = +3
Query: 324 YVWQVGNWSACPKNCGGNGLQNRDVNCFLMTSKGQFLPAKLSKCNYKLEPRRYIS-CGQI 500
++W W C CGG G + V+C + +K L S C P + C
Sbjct: 802 FIWTHSGWEGCSVQCGG-GERRTIVSCTRIVNKTTTL-VNDSDCPQASRPEPQVRRCNLH 859
Query: 501 DCPPKFLASKWGKCQESATCQPVVRQREVKCVSLLSTGKLKIQSPGICYQMGQRP 665
C +++A W C SATC+ + REV CV L G P C G RP
Sbjct: 860 PCQSRWVAGPWSPC--SATCEKGFQHREVTCVYQLQNGTHVATRPLYC--PGPRP 910
Score = 30.4 bits (67), Expect = 4.9
Identities = 11/25 (44%), Positives = 13/25 (52%)
Frame = +3
Query: 126 WSPIDEWSPCSKPCGVGVETQTFVC 200
WSP WS CS+ CG G + C
Sbjct: 546 WSPWGAWSMCSRTCGTGARFRQRKC 570
>sp|Q9H324|ATS10_HUMAN ADAMTS-10 precursor (A disintegrin and metalloproteinase with
thrombospondin motifs 10) (ADAM-TS 10) (ADAM-TS10)
Length = 1077
Score = 72.8 bits (177), Expect = 9e-13
Identities = 47/156 (30%), Positives = 71/156 (45%), Gaps = 1/156 (0%)
Frame = +3
Query: 135 IDEWSPCSKPCGVGVETQTFVCLKKTRYRTLEYTEKPKCPLSTRPNQTRNCSLGDCQNDS 314
+ WS CS+ C GV +++ VC ++ + + CP RP C C +
Sbjct: 864 VGNWSLCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACP-QPRPPVLEACHGPTCPPE- 921
Query: 315 FGSYVWQVGNWSACPKNCGGNGLQNRDVNCFLMTSKGQFLPAKLSKCNYKLEPRRYISCG 494
W +WS C +C G GL++R V C + PA C+ +P + C
Sbjct: 922 -----WAALDWSECTPSC-GPGLRHRVVLCKSADHRATLPPA---HCSPAAKPPATMRCN 972
Query: 495 QIDCPP-KFLASKWGKCQESATCQPVVRQREVKCVS 599
CPP +++A +WG+C SA C RQR V+C S
Sbjct: 973 LRRCPPARWVAGEWGEC--SAQCGVGQRQRSVRCTS 1006
Score = 53.1 bits (126), Expect = 7e-07
Identities = 35/114 (30%), Positives = 45/114 (39%)
Frame = +3
Query: 309 DSFGSYVWQVGNWSACPKNCGGNGLQNRDVNCFLMTSKGQFLPAKLSKCNYKLEPRRYIS 488
DS Y W W+ C C G G Q + V C P S + KL P+R +
Sbjct: 796 DSLPPYSWHYAPWTKCSAQCAG-GSQVQAVECRNQLDSSAVAPHYCS-AHSKL-PKRQRA 852
Query: 489 CGQIDCPPKFLASKWGKCQESATCQPVVRQREVKCVSLLSTGKLKIQSPGICYQ 650
C CPP ++ W C S +C VR R V C +S + K C Q
Sbjct: 853 CNTEPCPPDWVVGNWSLC--SRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQ 904
Score = 32.3 bits (72), Expect = 1.3
Identities = 17/49 (34%), Positives = 22/49 (44%)
Frame = +3
Query: 141 EWSPCSKPCGVGVETQTFVCLKKTRYRTLEYTEKPKCPLSTRPNQTRNC 287
EW CS CGVG ++ C T + E TE + RP T+ C
Sbjct: 985 EWGECSAQCGVGQRQRSVRCTSHTGQASHECTE------ALRPPTTQQC 1027
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,674,809
Number of Sequences: 369166
Number of extensions: 2025910
Number of successful extensions: 5770
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5044
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5535
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6365071885
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)