Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_020_G10
(826 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P20241|NRG_DROME Neuroglian precursor 129 1e-29
sp|Q98902|L1CAM_FUGRU Neural cell adhesion molecule L1 prec... 100 6e-21
sp|Q9P232|CNTN3_HUMAN Contactin 3 precursor (Brain-derived ... 96 1e-19
sp|Q810U3|NFASC_MOUSE Neurofascin precursor 95 2e-19
sp|P35331|NRCAM_CHICK Neuronal cell adhesion molecule precu... 95 3e-19
sp|P97685|NFASC_RAT Neurofascin precursor 94 5e-19
sp|Q07409|CNTN3_MOUSE Contactin 3 precursor (Brain-derived ... 94 6e-19
sp|Q92823|NRCAM_HUMAN Neuronal cell adhesion molecule precu... 93 1e-18
sp|Q62682|CNTN3_RAT Contactin 3 precursor (Brain-derived im... 92 1e-18
sp|Q810U4|NRCAM_MOUSE Neuronal cell adhesion molecule precu... 89 1e-17
>sp|P20241|NRG_DROME Neuroglian precursor
Length = 1302
Score = 129 bits (323), Expect = 1e-29
Identities = 93/270 (34%), Positives = 120/270 (44%)
Frame = +1
Query: 1 SLIIMGAQTTDTGIYTCNATNGLDFDVAYATLIVQGKPHTPIDIKADCSRFANKGEAVVS 180
SL I D+G YTC A LD A A LIVQ P+ P C A+K E +
Sbjct: 578 SLTIAKTMELDSGEYTCVARTRLDEATARANLIVQDVPNAPKLTGITCQ--ADKAE--IH 633
Query: 181 WNSGADNYAPIIMYMVEYSTQFDRRGWYEVQ*VTQVTGSTGETVDVRVSMQPNIQYQFRV 360
W DN +PI+ Y ++++T F W T S+ V M P Y FRV
Sbjct: 634 WEQQGDNRSPILHYTIQFNTSFTPASWDAAYEKVPNTDSS-----FVVQMSPWANYTFRV 688
Query: 361 RAMNRVGVSEPSDVTTNRCGLPPTIPNSNPKNVFVYGTARDNLVIQWTPMTYVEHCGPKL 540
A N++G S PS ++ C P +P NP NV GT +NLVI WTPM +EH P
Sbjct: 689 IAFNKIGASPPS-AHSDSCTTQPDVPFKNPDNVVGQGTEPNNLVISWTPMPEIEHNAPNF 747
Query: 541 GYDISVICITCKSIPTDKVNTTFISDWDQNIVTYYNFQLGSVTYDMESFQKFKVIIRAKN 720
Y +S + IP I DW QN + V D +F K+ + + A N
Sbjct: 748 HYYVS----WKRDIPAAAWENNNIFDWRQNNI---------VIADQPTFVKYLIKVVAIN 794
Query: 721 EIGFSKSNDTVGYGYSGDAPPTVVPTQLTM 810
+ G S GYSG+ P PT TM
Sbjct: 795 DRGESNVAAEEVVGYSGEDRPLDAPTNFTM 824
Score = 30.0 bits (66), Expect = 8.1
Identities = 15/30 (50%), Positives = 17/30 (56%)
Frame = +1
Query: 31 DTGIYTCNATNGLDFDVAYATLIVQGKPHT 120
DTG Y CNATN L + L VQ +P T
Sbjct: 404 DTGNYGCNATNSLGYVYKDVYLNVQAEPPT 433
>sp|Q98902|L1CAM_FUGRU Neural cell adhesion molecule L1 precursor (N-CAM L1) (L1-CAM)
Length = 1277
Score = 100 bits (248), Expect = 6e-21
Identities = 75/268 (27%), Positives = 118/268 (44%), Gaps = 1/268 (0%)
Frame = +1
Query: 4 LIIMGAQTTDTGIYTCNATNGLDFDVAYATLIVQGKPHTPIDIKADCSRFANKGEAVVSW 183
LII + D G+YTC LD A +TL + +P P+ ++ A ++W
Sbjct: 592 LIISNVEPGDEGVYTCQIITKLDMVEASSTLTLCDRPDPPVHLQV---TNAKHRVVTLNW 648
Query: 184 NSGADNYAPIIMYMVEYSTQ-FDRRGWYEVQ*VTQVTGSTGETVDVRVSMQPNIQYQFRV 360
G DN +PI+ Y+VE+ Q GW E++ V + V + + P + Y+FRV
Sbjct: 649 TPGDDNNSPILEYVVEFEDQDMKENGWEELKRV------AADKKHVNLPLWPYMSYRFRV 702
Query: 361 RAMNRVGVSEPSDVTTNRCGLPPTIPNSNPKNVFVYGTARDNLVIQWTPMTYVEHCGPKL 540
A+N G S+PS + ++ P P+SNP++V T D LVI W M GP
Sbjct: 703 IAINDQGKSDPSKL-SDLYKTPADAPDSNPEDVRSESTDPDTLVITWEEMDKRNFNGPDF 761
Query: 541 GYDISVICITCKSIPTDKVNTTFISDWDQNIVTYYNFQLGSVTYDMESFQKFKVIIRAKN 720
Y + + DW + Y + D+++F F++ ++A N
Sbjct: 762 KYLVMWRRVVGSG-----------PDWHEE----YTIAPPFIVTDVQNFSAFEIKVQAVN 806
Query: 721 EIGFSKSNDTVGYGYSGDAPPTVVPTQL 804
+ G D + GYSG+ P P L
Sbjct: 807 KKGLGPEPDPI-IGYSGEDVPLEAPLNL 833
>sp|Q9P232|CNTN3_HUMAN Contactin 3 precursor (Brain-derived immunoglobulin superfamily
protein 1) (BIG-1) (Plasmacytoma-associated neuronal
glycoprotein)
Length = 1028
Score = 95.9 bits (237), Expect = 1e-19
Identities = 77/273 (28%), Positives = 120/273 (43%), Gaps = 5/273 (1%)
Frame = +1
Query: 4 LIIMGAQTTDTGIYTCNATNGLDFDVAYATLIVQGKPHTPIDIKADCSRFANKGEAVVSW 183
L+I Q +G Y C G+D + A LIV+G P P ++K D A +SW
Sbjct: 562 LMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGSPGPPENVKVD---EITDTTAQLSW 618
Query: 184 NSGADNYAPIIMYMVEYSTQFDRRGWYEVQ*VTQVTGSTGETVDVRVSMQPNIQYQFRVR 363
G DN++P+I Y ++ T F GW V V +V T V V + P ++Y+FRV
Sbjct: 619 KEGKDNHSPVISYSIQARTPFS-VGWQTVTTVPEVIDGKTHTATV-VELNPWVEYEFRVV 676
Query: 364 AMNRVGVSEPSDVTTNRCGLPPTIPNSNPKNVFVYGTARDNLVIQWTPMTYVEHCGPKLG 543
A N++G EPS + + + +P P V G +R LVI W P+ G G
Sbjct: 677 ASNKIGGGEPS-LPSEKVRTEEAVPEVPPSEVNGGGGSRSELVITWDPVPEELQNGEGFG 735
Query: 544 YDISVICITCKSIPTDKVNTTFISDWDQNIVT-----YYNFQLGSVTYDMESFQKFKVII 708
Y ++ ++ W Q +VT Y F+ S+ + ++V +
Sbjct: 736 YVVA-------------FRPLGVTTWIQTVVTSPDTPRYVFRNESIV----PYSPYEVKV 778
Query: 709 RAKNEIGFSKSNDTVGYGYSGDAPPTVVPTQLT 807
N G + V +S + PTV P+Q++
Sbjct: 779 GVYNNKGEGPFS-PVTTVFSAEEEPTVAPSQVS 810
>sp|Q810U3|NFASC_MOUSE Neurofascin precursor
Length = 1240
Score = 95.1 bits (235), Expect = 2e-19
Identities = 81/278 (29%), Positives = 126/278 (45%), Gaps = 16/278 (5%)
Frame = +1
Query: 1 SLIIMGAQTTDTGIYTCNATNGLDFDVAYATLIV---------------QGKPHTPIDIK 135
SL I G D G YTC A+ LD D+A A L V +G+P P D+
Sbjct: 576 SLTIFGVAERDQGSYTCMASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDL- 634
Query: 136 ADCSRFANKGEAVVSWNSGADNYAPIIMYMVEYST-QFDRRGWYEVQ*VTQVTGSTGETV 312
+ + A + + +W G DN +PI Y+V++ QF W++ ++ GS V
Sbjct: 635 -ELTDLAERSVRL-TWIPGDDNNSPITDYVVQFEEDQFQPGVWHDH---SRFPGSVNSAV 689
Query: 313 DVRVSMQPNIQYQFRVRAMNRVGVSEPSDVTTNRCGLPPTIPNSNPKNVFVYGTARDNLV 492
+ + P + YQFRV A+N VG S PS + + R P SNP +V GT ++N+
Sbjct: 690 ---LHLSPYVNYQFRVIAVNEVGSSHPS-LPSERYRTSGAPPESNPSDVKGEGTRKNNME 745
Query: 493 IQWTPMTYVEHCGPKLGYDISVICITCKSIPTDKVNTTFISDWDQNIVTYYNFQLGSVTY 672
I WTPM GP L Y + + T + W+ V + +G
Sbjct: 746 ITWTPMNATSAFGPNLRY-----IVKWRRRETRET-------WNNVTVWGSRYVVGQTPV 793
Query: 673 DMESFQKFKVIIRAKNEIGFSKSNDTVGYGYSGDAPPT 786
+ +++ ++A+N+ G DT+ GYSG+ P+
Sbjct: 794 ----YVPYEIRVQAENDFGKGPEPDTI-IGYSGEDLPS 826
>sp|P35331|NRCAM_CHICK Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related
cell adhesion molecule) (Ng-CAM-related) (hBravo)
Length = 1284
Score = 94.7 bits (234), Expect = 3e-19
Identities = 79/272 (29%), Positives = 121/272 (44%), Gaps = 7/272 (2%)
Frame = +1
Query: 1 SLIIMGAQTTDTGIYTCNATNGLDFDVAYATLIVQGKPHTPIDIKA------DCSRFANK 162
+L IM D G YTC LD A A L V P TP I A D
Sbjct: 576 NLTIMNVTDKDDGTYTCIVNTTLDSVSASAVLTVVAAPPTPAIIYARPNPPLDLELTGQL 635
Query: 163 GEAV-VSWNSGADNYAPIIMYMVEYSTQFDRRGWYEVQ*VTQVTGSTGETVDVRVSMQPN 339
++ +SW G +N +PI +++EY G + Q T+V GS V++ + P
Sbjct: 636 ERSIELSWVPGEENNSPITNFVIEYEDGLHEPGVWHYQ--TEVPGSH---TTVQLKLSPY 690
Query: 340 IQYQFRVRAMNRVGVSEPSDVTTNRCGLPPTIPNSNPKNVFVYGTARDNLVIQWTPMTYV 519
+ Y FRV A+N +G S+PS+ + P+ NP NV G+ DNLVI W +
Sbjct: 691 VNYSFRVIAVNEIGRSQPSEPSEQYLTKSAN-PDENPSNVQGIGSEPDNLVITWESLKGF 749
Query: 520 EHCGPKLGYDISVICITCKSIPTDKVNTTFISDWDQNIVTYYNFQLGSVTYDMESFQKFK 699
+ GP L Y +S + D +W +V + + S T +F ++
Sbjct: 750 QSNGPGLQYKVS-----WRQKDVD-------DEWTSVVVANVSKYIVSGT---PTFVPYE 794
Query: 700 VIIRAKNEIGFSKSNDTVGYGYSGDAPPTVVP 795
+ ++A N++G++ V G+SG+ P V P
Sbjct: 795 IKVQALNDLGYAPEPSEV-IGHSGEDLPMVAP 825
>sp|P97685|NFASC_RAT Neurofascin precursor
Length = 1240
Score = 94.0 bits (232), Expect = 5e-19
Identities = 81/278 (29%), Positives = 126/278 (45%), Gaps = 16/278 (5%)
Frame = +1
Query: 1 SLIIMGAQTTDTGIYTCNATNGLDFDVAYATLIV---------------QGKPHTPIDIK 135
SL I G D G YTC A+ LD D+A A L V +G+P P D+
Sbjct: 576 SLTIFGVAERDQGSYTCMASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDL- 634
Query: 136 ADCSRFANKGEAVVSWNSGADNYAPIIMYMVEYST-QFDRRGWYEVQ*VTQVTGSTGETV 312
+ + A + + +W G DN +PI Y+V++ QF W++ ++ GS V
Sbjct: 635 -ELTDLAERSVRL-TWIPGDDNNSPITDYVVQFEEDQFQPGVWHDH---SKFPGSVNSAV 689
Query: 313 DVRVSMQPNIQYQFRVRAMNRVGVSEPSDVTTNRCGLPPTIPNSNPKNVFVYGTARDNLV 492
+ + P + YQFRV A+N VG S PS + + R P SNP +V GT ++N+
Sbjct: 690 ---LHLSPYVNYQFRVIAVNEVGSSHPS-LPSERYRTSGAPPESNPSDVKGEGTRKNNME 745
Query: 493 IQWTPMTYVEHCGPKLGYDISVICITCKSIPTDKVNTTFISDWDQNIVTYYNFQLGSVTY 672
I WTPM GP L Y + + T + W+ V + +G
Sbjct: 746 ITWTPMNATSAFGPNLRY-----IVKWRRRETRET-------WNNVTVWGSRYVVGQTPV 793
Query: 673 DMESFQKFKVIIRAKNEIGFSKSNDTVGYGYSGDAPPT 786
+ +++ ++A+N+ G +TV GYSG+ P+
Sbjct: 794 ----YVPYEIRVQAENDFGKGPEPETV-IGYSGEDLPS 826
>sp|Q07409|CNTN3_MOUSE Contactin 3 precursor (Brain-derived immunoglobulin superfamily
protein 1) (BIG-1) (Plasmacytoma-associated neuronal
glycoprotein)
Length = 1028
Score = 93.6 bits (231), Expect = 6e-19
Identities = 76/273 (27%), Positives = 119/273 (43%), Gaps = 5/273 (1%)
Frame = +1
Query: 4 LIIMGAQTTDTGIYTCNATNGLDFDVAYATLIVQGKPHTPIDIKADCSRFANKGEAVVSW 183
L+I Q +G Y C G+D + A LIV+G P P ++K D A +SW
Sbjct: 562 LMIRNIQLKHSGKYVCMVQTGVDSVSSAAELIVRGSPGPPENVKVD---EITDTTAQLSW 618
Query: 184 NSGADNYAPIIMYMVEYSTQFDRRGWYEVQ*VTQVTGSTGETVDVRVSMQPNIQYQFRVR 363
G D+++P+I Y V+ T F GW V+ V +V T V V + P ++Y+FR+
Sbjct: 619 TEGTDSHSPVISYAVQARTPFS-VGWQSVRTVPEVIDGKTHTATV-VELNPWVEYEFRIV 676
Query: 364 AMNRVGVSEPSDVTTNRCGLPPTIPNSNPKNVFVYGTARDNLVIQWTPMTYVEHCGPKLG 543
A N++G EPS + + + P P V G +R LVI W P+ G G
Sbjct: 677 ASNKIGGGEPS-LPSEKVRTEEAAPEIAPSEVSGGGGSRSELVITWDPVPEELQNGGGFG 735
Query: 544 YDISVICITCKSIPTDKVNTTFISDWDQNIVT-----YYNFQLGSVTYDMESFQKFKVII 708
Y ++ ++ W Q +VT Y F+ S+ F ++V +
Sbjct: 736 YVVA-------------FRPLGVTTWIQTVVTSPDNPRYVFRNESIV----PFSPYEVKV 778
Query: 709 RAKNEIGFSKSNDTVGYGYSGDAPPTVVPTQLT 807
N G + V +S + PTV P+ ++
Sbjct: 779 GVYNNKGEGPFS-PVTTVFSAEEEPTVAPSHIS 810
>sp|Q92823|NRCAM_HUMAN Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related
cell adhesion molecule) (Ng-CAM-related) (hBravo)
Length = 1304
Score = 92.8 bits (229), Expect = 1e-18
Identities = 80/271 (29%), Positives = 123/271 (45%), Gaps = 7/271 (2%)
Frame = +1
Query: 4 LIIMGAQTTDTGIYTCNATNGLDFDVAYATLIVQGKPHTPIDI------KADCSRFANKG 165
L++ D+G YTC A LD A A L V TP + D
Sbjct: 601 LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLD 660
Query: 166 EAV-VSWNSGADNYAPIIMYMVEYSTQFDRRGWYEVQ*VTQVTGSTGETVDVRVSMQPNI 342
++V +SW G DN +PI +++EY + G + Q T+V+G T T +++S P +
Sbjct: 661 KSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQ--TEVSG-TQTTAQLKLS--PYV 715
Query: 343 QYQFRVRAMNRVGVSEPSDVTTNRCGLPPTIPNSNPKNVFVYGTARDNLVIQWTPMTYVE 522
Y FRV A+N +G S PS+ + + P+ NP V G+ DNLVI W P+ E
Sbjct: 716 NYSFRVMAVNSIGKSLPSEASEQYL-TKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFE 774
Query: 523 HCGPKLGYDISVICITCKSIPTDKVNTTFISDWDQNIVTYYNFQLGSVTYDMESFQKFKV 702
GP L Y +S + D +W +V + + S T +F + +
Sbjct: 775 SNGPGLQYKVS-----WRQKDGD-------DEWTSVVVANVSKYIVSGT---PTFVPYLI 819
Query: 703 IIRAKNEIGFSKSNDTVGYGYSGDAPPTVVP 795
++A N++GF+ V G+SG+ P V P
Sbjct: 820 KVQALNDMGFA-PEPAVVMGHSGEDLPMVAP 849
>sp|Q62682|CNTN3_RAT Contactin 3 precursor (Brain-derived immunoglobulin superfamily
protein 1) (BIG-1)
Length = 1028
Score = 92.4 bits (228), Expect = 1e-18
Identities = 76/273 (27%), Positives = 118/273 (43%), Gaps = 5/273 (1%)
Frame = +1
Query: 4 LIIMGAQTTDTGIYTCNATNGLDFDVAYATLIVQGKPHTPIDIKADCSRFANKGEAVVSW 183
L+I Q +G Y C G+D + A LIV+G P P ++K D A +SW
Sbjct: 562 LMIRNIQLKHSGKYVCMVQTGVDSVSSAAELIVRGSPGPPENVKVD---EITDTTAQLSW 618
Query: 184 NSGADNYAPIIMYMVEYSTQFDRRGWYEVQ*VTQVTGSTGETVDVRVSMQPNIQYQFRVR 363
G D+++P+I Y V+ T F GW V+ V + T V V + P ++Y+FRV
Sbjct: 619 TEGTDSHSPVISYAVQARTPFS-VGWQNVRTVPEAIDGKTRTATV-VELNPWVEYEFRVV 676
Query: 364 AMNRVGVSEPSDVTTNRCGLPPTIPNSNPKNVFVYGTARDNLVIQWTPMTYVEHCGPKLG 543
A N++G EPS + + + P P V G +R LVI W P+ G G
Sbjct: 677 ASNKIGGGEPS-LPSEKVRTEEAAPEVAPSEVSGGGGSRSELVITWDPVPEELQNGGGFG 735
Query: 544 YDISVICITCKSIPTDKVNTTFISDWDQNIVT-----YYNFQLGSVTYDMESFQKFKVII 708
Y ++ ++ W Q +VT Y F+ S+ F ++V +
Sbjct: 736 YVVA-------------FRPLGVTTWIQTVVTSPDNPRYVFRNESIV----PFSPYEVKV 778
Query: 709 RAKNEIGFSKSNDTVGYGYSGDAPPTVVPTQLT 807
N G + V +S + PTV P+ ++
Sbjct: 779 GVYNNKGEGPFS-PVTTVFSAEEEPTVAPSHIS 810
>sp|Q810U4|NRCAM_MOUSE Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related
cell adhesion molecule) (Ng-CAM-related) (mBravo)
Length = 1256
Score = 89.0 bits (219), Expect = 1e-17
Identities = 79/271 (29%), Positives = 119/271 (43%), Gaps = 7/271 (2%)
Frame = +1
Query: 4 LIIMGAQTTDTGIYTCNATNGLDFDVAYATLIVQGKPHTPIDI------KADCSRFANKG 165
L++ + D G YTC A LD A A L V TP I D
Sbjct: 595 LVVSDVKDDDGGTYTCTANTTLDSASASAVLRVVAPTPTPAPIYDVPNPPFDLELTNQLD 654
Query: 166 EAV-VSWNSGADNYAPIIMYMVEYSTQFDRRGWYEVQ*VTQVTGSTGETVDVRVSMQPNI 342
++V ++W G DN +PI +++EY G + Q +V+G T T +++S P +
Sbjct: 655 KSVQLTWTPGDDNNSPITKFIIEYEDAMHDAGLWRHQ--AEVSG-TQTTAQLKLS--PYV 709
Query: 343 QYQFRVRAMNRVGVSEPSDVTTNRCGLPPTIPNSNPKNVFVYGTARDNLVIQWTPMTYVE 522
Y FRV A N +G S PS+ + P+ NP V GT DNLVI W P+ +
Sbjct: 710 NYSFRVMAENSIGRSMPSEASEQYL-TKAAEPDQNPMAVEGLGTEPDNLVITWKPLNGFQ 768
Query: 523 HCGPKLGYDISVICITCKSIPTDKVNTTFISDWDQNIVTYYNFQLGSVTYDMESFQKFKV 702
GP L Y +S + D +W +V + + S T +F + +
Sbjct: 769 SNGPGLQYKVS-----WRQKDGD-------DEWTSVVVANVSKYIVSGT---PTFVPYLI 813
Query: 703 IIRAKNEIGFSKSNDTVGYGYSGDAPPTVVP 795
++A N++GF+ V G+SG+ P V P
Sbjct: 814 KVQALNDVGFAPEPAAV-MGHSGEDLPMVAP 843
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 97,925,481
Number of Sequences: 369166
Number of extensions: 2059961
Number of successful extensions: 5191
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4598
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5071
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7956112725
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)