Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_020_G01 (913 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P48721|GRP75_RAT Stress-70 protein, mitochondrial precur... 363 e-100 sp|P38646|GRP75_HUMAN Stress-70 protein, mitochondrial prec... 363 e-100 sp|P38647|GRP75_MOUSE Stress-70 protein, mitochondrial prec... 363 e-100 sp|O35501|GRP75_CRIGR Stress-70 protein, mitochondrial prec... 362 e-100 sp|P29845|HSP7E_DROME Heat shock 70 kDa protein cognate 5 360 3e-99 sp|P11141|HSP7F_CAEEL Heat shock 70 kDa protein F, mitochon... 353 4e-97 sp|Q8YE76|DNAK_BRUME Chaperone protein dnaK (Heat shock pro... 272 1e-72 sp|P94317|DNAK_BRAJA Chaperone protein dnaK (Heat shock pro... 271 1e-72 sp|Q8FXX2|DNAK_BRUSU Chaperone protein dnaK (Heat shock pro... 271 2e-72 sp|O05700|DNAK_RHOS7 Chaperone protein dnaK (Heat shock pro... 268 1e-71
>sp|P48721|GRP75_RAT Stress-70 protein, mitochondrial precursor (75 kDa glucose regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (MTHSP70) (Mortalin) Length = 679 Score = 363 bits (933), Expect = e-100 Identities = 186/255 (72%), Positives = 215/255 (84%) Frame = +2 Query: 2 LFGRVPSKSVNPDEAVAMGAAIQXXXXXXXXXXXXXXXXXXXXXXIETLGGVFTKLINRN 181 LFGR PSK+VNPDEAVA+GAAIQ IETLGGVFTKLINRN Sbjct: 402 LFGRAPSKAVNPDEAVAIGAAIQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTKLINRN 461 Query: 182 TTIPTKKSQVFSTAADGQTQVEIKVHQGEREMAADNKILGQFSLIGIPPAPRGVPQIEVT 361 TTIPTKKSQVFSTAADGQTQVEIKV QGEREMA DNK+LGQF+LIGIPPAPRGVPQIEVT Sbjct: 462 TTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVT 521 Query: 362 FDIDANGIVNVSARDKGTGKEQQIVIQSSGGLSKDEIENMIKRAEENAENDKRKREMVEV 541 FDIDANGIV+VSA+DKGTG+EQQIVIQSSGGLSKD+IENM+K AE+ AE D+RK+E VE Sbjct: 522 FDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEA 581 Query: 542 VNQAEGIVYDTESKIDEFKNQLPAEECEKLRNLIQQVRDKLANKDNESAESIKKATNELQ 721 VN AEGIV+DTE+K++EFK+QLPA+EC KL+ I ++R+ LA KD+E+ E+I++A + LQ Sbjct: 582 VNMAEGIVHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQ 641 Query: 722 QSSLKLFEMAYKKMA 766 Q+SLKLFEMAYKKMA Sbjct: 642 QASLKLFEMAYKKMA 656
>sp|P38646|GRP75_HUMAN Stress-70 protein, mitochondrial precursor (75 kDa glucose regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (Mortalin) (MOT) Length = 679 Score = 363 bits (932), Expect = e-100 Identities = 185/255 (72%), Positives = 215/255 (84%) Frame = +2 Query: 2 LFGRVPSKSVNPDEAVAMGAAIQXXXXXXXXXXXXXXXXXXXXXXIETLGGVFTKLINRN 181 LFGR PSK+VNPDEAVA+GAAIQ IETLGGVFTKLINRN Sbjct: 402 LFGRAPSKAVNPDEAVAIGAAIQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTKLINRN 461 Query: 182 TTIPTKKSQVFSTAADGQTQVEIKVHQGEREMAADNKILGQFSLIGIPPAPRGVPQIEVT 361 TTIPTKKSQVFSTAADGQTQVEIKV QGEREMA DNK+LGQF+LIGIPPAPRGVPQIEVT Sbjct: 462 TTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVT 521 Query: 362 FDIDANGIVNVSARDKGTGKEQQIVIQSSGGLSKDEIENMIKRAEENAENDKRKREMVEV 541 FDIDANGIV+VSA+DKGTG+EQQIVIQSSGGLSKD+IENM+K AE+ AE D+RK+E VE Sbjct: 522 FDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEA 581 Query: 542 VNQAEGIVYDTESKIDEFKNQLPAEECEKLRNLIQQVRDKLANKDNESAESIKKATNELQ 721 VN AEGI++DTE+K++EFK+QLPA+EC KL+ I ++R+ LA KD+E+ E+I++A + LQ Sbjct: 582 VNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQ 641 Query: 722 QSSLKLFEMAYKKMA 766 Q+SLKLFEMAYKKMA Sbjct: 642 QASLKLFEMAYKKMA 656
>sp|P38647|GRP75_MOUSE Stress-70 protein, mitochondrial precursor (75 kDa glucose regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (P66 MOT) (Mortalin) Length = 679 Score = 363 bits (931), Expect = e-100 Identities = 186/255 (72%), Positives = 214/255 (83%) Frame = +2 Query: 2 LFGRVPSKSVNPDEAVAMGAAIQXXXXXXXXXXXXXXXXXXXXXXIETLGGVFTKLINRN 181 LFGR PSK+VNPDEAVA+GAAIQ IETLGGVFTKLINRN Sbjct: 402 LFGRAPSKAVNPDEAVAIGAAIQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTKLINRN 461 Query: 182 TTIPTKKSQVFSTAADGQTQVEIKVHQGEREMAADNKILGQFSLIGIPPAPRGVPQIEVT 361 TTIPTKKSQVFSTAADGQTQVEIKV QGEREMA DNK+LGQF+LIGIPPAPRGVPQIEVT Sbjct: 462 TTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVT 521 Query: 362 FDIDANGIVNVSARDKGTGKEQQIVIQSSGGLSKDEIENMIKRAEENAENDKRKREMVEV 541 FDIDANGIV+VSA+DKGTG+EQQIVIQSSGGLSKD+IENM+K AE+ AE D+RK+E VE Sbjct: 522 FDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEA 581 Query: 542 VNQAEGIVYDTESKIDEFKNQLPAEECEKLRNLIQQVRDKLANKDNESAESIKKATNELQ 721 VN AEGI++DTE+K++EFK+QLPA+EC KL+ I +VR LA KD+E+ E+I++A + LQ Sbjct: 582 VNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKVRALLARKDSETGENIRQAASSLQ 641 Query: 722 QSSLKLFEMAYKKMA 766 Q+SLKLFEMAYKKMA Sbjct: 642 QASLKLFEMAYKKMA 656
>sp|O35501|GRP75_CRIGR Stress-70 protein, mitochondrial precursor (75 kDa glucose regulated protein) (GRP 75) Length = 679 Score = 362 bits (930), Expect = e-100 Identities = 184/255 (72%), Positives = 215/255 (84%) Frame = +2 Query: 2 LFGRVPSKSVNPDEAVAMGAAIQXXXXXXXXXXXXXXXXXXXXXXIETLGGVFTKLINRN 181 LFGR PSK+VNPDEAVA+GAAIQ IETLGGVFTKLINRN Sbjct: 402 LFGRAPSKAVNPDEAVAIGAAIQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTKLINRN 461 Query: 182 TTIPTKKSQVFSTAADGQTQVEIKVHQGEREMAADNKILGQFSLIGIPPAPRGVPQIEVT 361 TTIPTKKSQVFSTAADGQTQVEIKV QGEREMA DNK+LGQF+LIGIPPAPRGVPQIEVT Sbjct: 462 TTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVT 521 Query: 362 FDIDANGIVNVSARDKGTGKEQQIVIQSSGGLSKDEIENMIKRAEENAENDKRKREMVEV 541 FD+DANGIV+VSA+DKGTG+EQQIVIQSSGGLSKD+IENM+K AE+ AE D+RK+E VE Sbjct: 522 FDLDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEA 581 Query: 542 VNQAEGIVYDTESKIDEFKNQLPAEECEKLRNLIQQVRDKLANKDNESAESIKKATNELQ 721 VN AEGI++DTE+K++EFK+QLPA+EC KL+ I ++R+ LA KD+E+ E+I++A + LQ Sbjct: 582 VNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQ 641 Query: 722 QSSLKLFEMAYKKMA 766 Q+SLKLFEMAYKKMA Sbjct: 642 QASLKLFEMAYKKMA 656
>sp|P29845|HSP7E_DROME Heat shock 70 kDa protein cognate 5 Length = 686 Score = 360 bits (924), Expect = 3e-99 Identities = 183/255 (71%), Positives = 212/255 (83%) Frame = +2 Query: 2 LFGRVPSKSVNPDEAVAMGAAIQXXXXXXXXXXXXXXXXXXXXXXIETLGGVFTKLINRN 181 LFGR PS+SVNPDEAVA+GAA+Q IETLGGVFT+LI+RN Sbjct: 402 LFGRQPSRSVNPDEAVAVGAAVQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTRLISRN 461 Query: 182 TTIPTKKSQVFSTAADGQTQVEIKVHQGEREMAADNKILGQFSLIGIPPAPRGVPQIEVT 361 TTIPTKKSQVFSTA+DGQTQVEIKVHQGEREMA DNK+LG F+L+GIPPAPRGVPQIEV Sbjct: 462 TTIPTKKSQVFSTASDGQTQVEIKVHQGEREMANDNKLLGSFTLVGIPPAPRGVPQIEVV 521 Query: 362 FDIDANGIVNVSARDKGTGKEQQIVIQSSGGLSKDEIENMIKRAEENAENDKRKREMVEV 541 FDIDANGIV+VSA+DKGTGKEQQIVIQSSGGLSKDEIENMIK+AEE A DK+KRE++E+ Sbjct: 522 FDIDANGIVHVSAKDKGTGKEQQIVIQSSGGLSKDEIENMIKKAEEYATADKQKRELIEI 581 Query: 542 VNQAEGIVYDTESKIDEFKNQLPAEECEKLRNLIQQVRDKLANKDNESAESIKKATNELQ 721 VNQ E IV+DTE+K++EFK+QLPAEECEKL+ I +R LANK+ E ++KAT+ LQ Sbjct: 582 VNQGESIVHDTETKMEEFKSQLPAEECEKLKKEIADLRTLLANKETADLEEVRKATSSLQ 641 Query: 722 QSSLKLFEMAYKKMA 766 QSSLKLFE+AYKKM+ Sbjct: 642 QSSLKLFELAYKKMS 656
>sp|P11141|HSP7F_CAEEL Heat shock 70 kDa protein F, mitochondrial precursor Length = 657 Score = 353 bits (906), Expect = 4e-97 Identities = 180/255 (70%), Positives = 206/255 (80%) Frame = +2 Query: 2 LFGRVPSKSVNPDEAVAMGAAIQXXXXXXXXXXXXXXXXXXXXXXIETLGGVFTKLINRN 181 +FG+VPSK+VNPDEAVAMGAAIQ IETLGG+ TKLI RN Sbjct: 381 IFGKVPSKAVNPDEAVAMGAAIQGAVLAGDVTDVLLLDVTPLSLGIETLGGIMTKLITRN 440 Query: 182 TTIPTKKSQVFSTAADGQTQVEIKVHQGEREMAADNKILGQFSLIGIPPAPRGVPQIEVT 361 TTIPTKKSQVFSTAADGQTQV+IKV QGEREMA NK+LGQFSL+GIPPAPRGVPQ+EVT Sbjct: 441 TTIPTKKSQVFSTAADGQTQVQIKVFQGEREMATSNKLLGQFSLVGIPPAPRGVPQVEVT 500 Query: 362 FDIDANGIVNVSARDKGTGKEQQIVIQSSGGLSKDEIENMIKRAEENAENDKRKREMVEV 541 FDIDANGIVNVSARD+GTGKEQQIVIQSSGGLSKD+IENMIK AE+NA D +++E+VEV Sbjct: 501 FDIDANGIVNVSARDRGTGKEQQIVIQSSGGLSKDQIENMIKEAEKNAAEDAKRKELVEV 560 Query: 542 VNQAEGIVYDTESKIDEFKNQLPAEECEKLRNLIQQVRDKLANKDNESAESIKKATNELQ 721 +NQAEGI++DTE+K+ EF +QLP +ECE LR I + L NKDNE+ E+IK+A N LQ Sbjct: 561 INQAEGIIHDTEAKMTEFADQLPKDECEALRTKIADTKKILDNKDNETPEAIKEACNTLQ 620 Query: 722 QSSLKLFEMAYKKMA 766 Q SLKLFE AYK MA Sbjct: 621 QQSLKLFEAAYKNMA 635
>sp|Q8YE76|DNAK_BRUME Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa protein) (HSP70) Length = 637 Score = 272 bits (695), Expect = 1e-72 Identities = 145/251 (57%), Positives = 176/251 (70%) Frame = +2 Query: 5 FGRVPSKSVNPDEAVAMGAAIQXXXXXXXXXXXXXXXXXXXXXXIETLGGVFTKLINRNT 184 FG+ P K VNPDE VAMGAAIQ IETLGGVFT+LI RNT Sbjct: 352 FGKEPHKGVNPDEVVAMGAAIQGGVLQGDVKDVLLLDVTPLSLGIETLGGVFTRLIERNT 411 Query: 185 TIPTKKSQVFSTAADGQTQVEIKVHQGEREMAADNKILGQFSLIGIPPAPRGVPQIEVTF 364 TIPTKKSQ FSTA D Q+ V I+V QGEREMAADNK+LGQF L+GIPPAPRGVPQIEVTF Sbjct: 412 TIPTKKSQTFSTAEDNQSAVTIRVFQGEREMAADNKLLGQFDLVGIPPAPRGVPQIEVTF 471 Query: 365 DIDANGIVNVSARDKGTGKEQQIVIQSSGGLSKDEIENMIKRAEENAENDKRKREMVEVV 544 DIDANGIVNVSA+DKGTGKE QI IQ+SGGLS +IE M+K AE NAE DK++RE VE Sbjct: 472 DIDANGIVNVSAKDKGTGKEHQIRIQASGGLSDADIEKMVKDAEANAEADKKRRESVEAK 531 Query: 545 NQAEGIVYDTESKIDEFKNQLPAEECEKLRNLIQQVRDKLANKDNESAESIKKATNELQQ 724 NQAE +V+ TE + E+ +++ A++ + + + I ++ L + E AE IK T L + Sbjct: 532 NQAESLVHSTEKSLAEYGDKVSADDKKAIEDAIAALKTSL---EGEDAEDIKAKTQALAE 588 Query: 725 SSLKLFEMAYK 757 S+KL + Y+ Sbjct: 589 VSMKLGQAMYE 599
>sp|P94317|DNAK_BRAJA Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa protein) (HSP70) Length = 633 Score = 271 bits (694), Expect = 1e-72 Identities = 145/255 (56%), Positives = 179/255 (70%) Frame = +2 Query: 2 LFGRVPSKSVNPDEAVAMGAAIQXXXXXXXXXXXXXXXXXXXXXXIETLGGVFTKLINRN 181 LFG+ P K VNPDE VA+GAAIQ IETLGGVFT++I+RN Sbjct: 351 LFGKEPHKGVNPDEVVAIGAAIQAGVLQGDVKDVLLLDVTPLSLGIETLGGVFTRIIDRN 410 Query: 182 TTIPTKKSQVFSTAADGQTQVEIKVHQGEREMAADNKILGQFSLIGIPPAPRGVPQIEVT 361 TTIPTKKSQVFSTA D Q V I+V QGEREMAADNK+LGQF L+GIPPAPRG+PQIEVT Sbjct: 411 TTIPTKKSQVFSTAEDNQNAVTIRVFQGEREMAADNKMLGQFDLMGIPPAPRGMPQIEVT 470 Query: 362 FDIDANGIVNVSARDKGTGKEQQIVIQSSGGLSKDEIENMIKRAEENAENDKRKREMVEV 541 FDIDANGIVNVSA+DK TGKEQQI IQ+SGGLS+ +IE M+K AE NAE DK++RE V Sbjct: 471 FDIDANGIVNVSAKDKATGKEQQIRIQASGGLSEADIEKMVKDAEANAEADKKRREAVTA 530 Query: 542 VNQAEGIVYDTESKIDEFKNQLPAEECEKLRNLIQQVRDKLANKDNESAESIKKATNELQ 721 N+A+G+V+ TE + E +++ E + + + +++ L D AE+IK T L Sbjct: 531 KNEADGLVHSTEKALAEHGSKVAETERRAIEDAVSDLKEALKGDD---AEAIKAKTQTLA 587 Query: 722 QSSLKLFEMAYKKMA 766 Q+S+KL E YK+ A Sbjct: 588 QASMKLGEAMYKQQA 602
>sp|Q8FXX2|DNAK_BRUSU Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa protein) (HSP70) Length = 637 Score = 271 bits (692), Expect = 2e-72 Identities = 144/251 (57%), Positives = 176/251 (70%) Frame = +2 Query: 5 FGRVPSKSVNPDEAVAMGAAIQXXXXXXXXXXXXXXXXXXXXXXIETLGGVFTKLINRNT 184 FG+ P K VNPDE VAMGAAIQ IETLGGVFT+LI RNT Sbjct: 352 FGKEPHKGVNPDEVVAMGAAIQGGVLQGDVKDVLLLDVTPLSLGIETLGGVFTRLIERNT 411 Query: 185 TIPTKKSQVFSTAADGQTQVEIKVHQGEREMAADNKILGQFSLIGIPPAPRGVPQIEVTF 364 TIPTKKSQ FSTA D Q+ V I+V QGEREMAADNK+LGQF L+GIPPAPRGVPQIEVTF Sbjct: 412 TIPTKKSQTFSTAEDNQSAVTIRVFQGEREMAADNKLLGQFDLVGIPPAPRGVPQIEVTF 471 Query: 365 DIDANGIVNVSARDKGTGKEQQIVIQSSGGLSKDEIENMIKRAEENAENDKRKREMVEVV 544 DIDANGIVNVSA+DKGTGKE QI IQ+SGGL+ +IE M+K AE NAE DK++RE VE Sbjct: 472 DIDANGIVNVSAKDKGTGKEHQIRIQASGGLTDADIEKMVKDAEANAEADKKRRESVEAK 531 Query: 545 NQAEGIVYDTESKIDEFKNQLPAEECEKLRNLIQQVRDKLANKDNESAESIKKATNELQQ 724 NQAE +V+ TE + E+ +++ A++ + + + I ++ L + E AE IK T L + Sbjct: 532 NQAESLVHSTEKSLAEYGDKVSADDKKAIEDAIAALKTSL---EGEDAEDIKAKTQALAE 588 Query: 725 SSLKLFEMAYK 757 S+KL + Y+ Sbjct: 589 VSMKLGQAMYE 599
>sp|O05700|DNAK_RHOS7 Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa protein) (HSP70) Length = 631 Score = 268 bits (686), Expect = 1e-71 Identities = 143/253 (56%), Positives = 176/253 (69%) Frame = +2 Query: 2 LFGRVPSKSVNPDEAVAMGAAIQXXXXXXXXXXXXXXXXXXXXXXIETLGGVFTKLINRN 181 LFG+ P K VNPDE VA+GAAIQ IETLGGVFT++I+RN Sbjct: 351 LFGKEPHKGVNPDEVVAIGAAIQAGVLQGDVKDVLLLDVTPLSLGIETLGGVFTRIIDRN 410 Query: 182 TTIPTKKSQVFSTAADGQTQVEIKVHQGEREMAADNKILGQFSLIGIPPAPRGVPQIEVT 361 TTIPTKKSQVFSTA D Q V I+V QGEREMAADNK+LGQF L+GIPPAPRG+PQIEVT Sbjct: 411 TTIPTKKSQVFSTAEDNQNAVTIRVFQGEREMAADNKMLGQFDLMGIPPAPRGMPQIEVT 470 Query: 362 FDIDANGIVNVSARDKGTGKEQQIVIQSSGGLSKDEIENMIKRAEENAENDKRKREMVEV 541 FDIDANGIVNVSA+DK TGKEQQI IQ+SGGLS EI+ M+K AE NA DK++RE V+ Sbjct: 471 FDIDANGIVNVSAKDKATGKEQQIRIQASGGLSDSEIDKMVKDAEANAAEDKKRREAVDA 530 Query: 542 VNQAEGIVYDTESKIDEFKNQLPAEECEKLRNLIQQVRDKLANKDNESAESIKKATNELQ 721 N A+ +V+ TE + E +++ E + + + +R+ L D AE+IK +N L Sbjct: 531 KNHADALVHSTEKALAEHGSKIDEGERRSIEDALSDLREALKGDD---AEAIKTKSNTLA 587 Query: 722 QSSLKLFEMAYKK 760 Q+S+KL E YK+ Sbjct: 588 QASMKLGEAMYKQ 600
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 84,995,299 Number of Sequences: 369166 Number of extensions: 1552432 Number of successful extensions: 6299 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5505 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5777 length of database: 68,354,980 effective HSP length: 110 effective length of database: 48,034,130 effective search space used: 9270587090 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)