Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_020_F12
(672 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5G268|NETR_HYLLE Neurotrypsin precursor 162 7e-40
sp|Q5G270|NETR_GORGO Neurotrypsin precursor 161 2e-39
sp|P56730|NETR_HUMAN Neurotrypsin precursor (Motopsin) (Ley... 160 2e-39
sp|Q5G266|NETR_TRAPH Neurotrypsin precursor 160 2e-39
sp|Q5G265|NETR_SAGLB Neurotrypsin precursor 160 2e-39
sp|Q5G267|NETR_MACMU Neurotrypsin precursor 160 2e-39
sp|Q9JIQ8|TMPS2_MOUSE Transmembrane protease, serine 2 (Epi... 159 6e-39
sp|Q5G269|NETR_PONPY Neurotrypsin precursor 158 1e-38
sp|Q91Y47|FA11_MOUSE Coagulation factor XI precursor (Plasm... 157 2e-38
sp|Q5G271|NETR_PANTR Neurotrypsin precursor 157 2e-38
>sp|Q5G268|NETR_HYLLE Neurotrypsin precursor
Length = 875
Score = 162 bits (410), Expect = 7e-40
Identities = 78/208 (37%), Positives = 123/208 (59%), Gaps = 7/208 (3%)
Frame = +1
Query: 1 WIIGAAHCYARPKNE---YRVRTGDWDNSADNNDKYEQVFEIEELILHPNWNNANYDYDL 171
W++ AAHC+ R N Y VR GD+ +++E+ ++++++H + + DYD+
Sbjct: 670 WVLTAAHCFKRYGNSTRNYAVRVGDYHTLVP--EEFEEEIGVQQIVIHREYRPDSSDYDI 727
Query: 172 ALIKIERNDGVGIKFNNYVQPVCLPKLGMMPDPN-TKCYVSGWGDTLATYPEKLLAAEVP 348
AL++++ + +F+++V P CLP P + CY++GWGDT Y L A +P
Sbjct: 728 ALVRLQGPEEQCARFSSHVLPACLPLWRERPQKTASNCYITGWGDTGRAYSRTLQQAAIP 787
Query: 349 LIKPERCYDFYKGRLTERMQCAG--YEAGGIDTCQGDSGGPLVCKVNG-IYTIFGATSWG 519
L+ C + YKGR T RM CAG +E +D+CQGDSGGPL+C+ G + ++G TSWG
Sbjct: 788 LLPKRFCEERYKGRFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWG 847
Query: 520 NGCAQPRNPGVYAKIQIMLEWVKEQTGL 603
+GC +PGVY K+ + W+K T L
Sbjct: 848 HGCGVKDSPGVYTKVSAFVPWIKSVTKL 875
>sp|Q5G270|NETR_GORGO Neurotrypsin precursor
Length = 876
Score = 161 bits (407), Expect = 2e-39
Identities = 78/208 (37%), Positives = 122/208 (58%), Gaps = 7/208 (3%)
Frame = +1
Query: 1 WIIGAAHCYARPKNE---YRVRTGDWDNSADNNDKYEQVFEIEELILHPNWNNANYDYDL 171
W++ AAHC+ R N Y VR GD+ +++E+ ++++++H + + DYD+
Sbjct: 671 WVLTAAHCFKRYGNSTRNYAVRVGDYHTLVP--EEFEEEIGVQQIVIHREYRPDSSDYDI 728
Query: 172 ALIKIERNDGVGIKFNNYVQPVCLPKLGMMPDPN-TKCYVSGWGDTLATYPEKLLAAEVP 348
AL++++ + +F+++V P CLP P + CY++GWGDT Y L A +P
Sbjct: 729 ALVRLQGPEEQCARFSSHVLPACLPLWRERPQKTASNCYITGWGDTGRAYSRTLQQAAIP 788
Query: 349 LIKPERCYDFYKGRLTERMQCAG--YEAGGIDTCQGDSGGPLVCKVNG-IYTIFGATSWG 519
L+ C + YKGR T RM CAG +E +D+CQGDSGGPL+C+ G + ++G TSWG
Sbjct: 789 LLPKRFCEERYKGRFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWG 848
Query: 520 NGCAQPRNPGVYAKIQIMLEWVKEQTGL 603
GC +PGVY K+ + W+K T L
Sbjct: 849 YGCGVKDSPGVYTKVSAFVPWIKSVTKL 876
>sp|P56730|NETR_HUMAN Neurotrypsin precursor (Motopsin) (Leydin)
Length = 875
Score = 160 bits (406), Expect = 2e-39
Identities = 78/208 (37%), Positives = 121/208 (58%), Gaps = 7/208 (3%)
Frame = +1
Query: 1 WIIGAAHCYARPKNE---YRVRTGDWDNSADNNDKYEQVFEIEELILHPNWNNANYDYDL 171
W++ AAHC+ R N Y VR GD+ +++E+ ++++++H + DYD+
Sbjct: 670 WVLTAAHCFKRYGNSTRSYAVRVGDYHTLVP--EEFEEEIGVQQIVIHREYRPDRSDYDI 727
Query: 172 ALIKIERNDGVGIKFNNYVQPVCLPKLGMMPDPN-TKCYVSGWGDTLATYPEKLLAAEVP 348
AL++++ + +F+++V P CLP P + CY++GWGDT Y L A +P
Sbjct: 728 ALVRLQGPEEQCARFSSHVLPACLPLWRERPQKTASNCYITGWGDTGRAYSRTLQQAAIP 787
Query: 349 LIKPERCYDFYKGRLTERMQCAG--YEAGGIDTCQGDSGGPLVCKVNG-IYTIFGATSWG 519
L+ C + YKGR T RM CAG +E +D+CQGDSGGPL+C+ G + ++G TSWG
Sbjct: 788 LLPKRFCEERYKGRFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWG 847
Query: 520 NGCAQPRNPGVYAKIQIMLEWVKEQTGL 603
GC +PGVY K+ + W+K T L
Sbjct: 848 YGCGVKDSPGVYTKVSAFVPWIKSVTKL 875
>sp|Q5G266|NETR_TRAPH Neurotrypsin precursor
Length = 875
Score = 160 bits (406), Expect = 2e-39
Identities = 78/208 (37%), Positives = 122/208 (58%), Gaps = 7/208 (3%)
Frame = +1
Query: 1 WIIGAAHCYARPKNE---YRVRTGDWDNSADNNDKYEQVFEIEELILHPNWNNANYDYDL 171
W++ AAHC+ R N Y VR GD+ +++E+ ++++++H + + DYD+
Sbjct: 670 WVLTAAHCFKRYGNSTRNYAVRVGDYHTLVP--EEFEEEIGVQQIVIHREYRPDSSDYDI 727
Query: 172 ALIKIERNDGVGIKFNNYVQPVCLPKLGMMPDPN-TKCYVSGWGDTLATYPEKLLAAEVP 348
AL++++ + +F+++V P CLP P + CY++GWGDT Y L A +P
Sbjct: 728 ALVRLQGPEEQCARFSSHVLPACLPFWRERPQKTASNCYITGWGDTGRAYSRTLQQAAIP 787
Query: 349 LIKPERCYDFYKGRLTERMQCAG--YEAGGIDTCQGDSGGPLVCKVNG-IYTIFGATSWG 519
L+ C + YKGR T RM CAG +E +D+CQGDSGGPL+C+ G + ++G TSWG
Sbjct: 788 LLPKRFCEERYKGRFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWAVYGVTSWG 847
Query: 520 NGCAQPRNPGVYAKIQIMLEWVKEQTGL 603
GC +PGVY K+ + W+K T L
Sbjct: 848 YGCGVKDSPGVYTKVSAFVPWIKSVTKL 875
>sp|Q5G265|NETR_SAGLB Neurotrypsin precursor
Length = 875
Score = 160 bits (406), Expect = 2e-39
Identities = 79/208 (37%), Positives = 121/208 (58%), Gaps = 7/208 (3%)
Frame = +1
Query: 1 WIIGAAHCYARPKNE---YRVRTGDWDNSADNNDKYEQVFEIEELILHPNWNNANYDYDL 171
W++ AAHC+ R N Y VR GD+ +++E+ ++E+++H + + DYD+
Sbjct: 670 WVLTAAHCFKRYGNSTRNYAVRVGDYHTLVP--EEFEEEIGVQEIVIHREYRPDSSDYDI 727
Query: 172 ALIKIERNDGVGIKFNNYVQPVCLPKLGMMPDPN-TKCYVSGWGDTLATYPEKLLAAEVP 348
AL++++ + +FN++V P CLP P + CY++GWGDT Y L A +
Sbjct: 728 ALVRLQGPEEQCARFNSHVLPACLPLWRERPQKTASNCYITGWGDTGQAYSRTLQQAAIH 787
Query: 349 LIKPERCYDFYKGRLTERMQCAG--YEAGGIDTCQGDSGGPLVCKVNG-IYTIFGATSWG 519
L+ C + YKGR T RM CAG +E +D+CQGDSGGPL+C+ G + ++G TSWG
Sbjct: 788 LLPKRFCEERYKGRFTGRMLCAGNLHEHKHVDSCQGDSGGPLMCERPGESWVVYGVTSWG 847
Query: 520 NGCAQPRNPGVYAKIQIMLEWVKEQTGL 603
GC +PGVY K+ + W+K T L
Sbjct: 848 YGCGVKDSPGVYTKVSAFVPWIKSVTKL 875
>sp|Q5G267|NETR_MACMU Neurotrypsin precursor
Length = 875
Score = 160 bits (406), Expect = 2e-39
Identities = 78/208 (37%), Positives = 122/208 (58%), Gaps = 7/208 (3%)
Frame = +1
Query: 1 WIIGAAHCYARPKNE---YRVRTGDWDNSADNNDKYEQVFEIEELILHPNWNNANYDYDL 171
W++ AAHC+ R N Y VR GD+ +++E+ ++++++H + + DYD+
Sbjct: 670 WVLTAAHCFKRYGNSTRNYAVRVGDYHTLVP--EEFEEEIGVQQIVIHREYRPDSSDYDI 727
Query: 172 ALIKIERNDGVGIKFNNYVQPVCLPKLGMMPDPN-TKCYVSGWGDTLATYPEKLLAAEVP 348
AL++++ + +F+++V P CLP P + CY++GWGDT Y L A +P
Sbjct: 728 ALVRLQGPEEQCARFSSHVLPACLPFWRERPQKTASNCYITGWGDTGRAYSRTLQQAAIP 787
Query: 349 LIKPERCYDFYKGRLTERMQCAG--YEAGGIDTCQGDSGGPLVCKVNG-IYTIFGATSWG 519
L+ C + YKGR T RM CAG +E +D+CQGDSGGPL+C+ G + ++G TSWG
Sbjct: 788 LLPKRFCEERYKGRFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWAVYGVTSWG 847
Query: 520 NGCAQPRNPGVYAKIQIMLEWVKEQTGL 603
GC +PGVY K+ + W+K T L
Sbjct: 848 YGCGVKDSPGVYTKVSAFVPWIKSVTKL 875
>sp|Q9JIQ8|TMPS2_MOUSE Transmembrane protease, serine 2 (Epitheliasin) (Plasmic
transmembrane protein X) [Contains: Transmembrane
protease, serine 2 non-catalytic chain; Transmembrane
protease, serine 2 catalytic chain]
Length = 490
Score = 159 bits (402), Expect = 6e-39
Identities = 81/202 (40%), Positives = 119/202 (58%), Gaps = 4/202 (1%)
Frame = +1
Query: 1 WIIGAAHCYARPKNEYRVRTGDWDNSADNNDKYEQVFEIEELILHPNWNNANYDYDLALI 180
WI+ AAHC P + R T + Y ++E++I HPN+++ + D+AL+
Sbjct: 288 WIVTAAHCVEEPLSGPRYWTAFAGILRQSLMFYGSRHQVEKVISHPNYDSKTKNNDIALM 347
Query: 181 KIERNDGVGIKFNNYVQPVCLPKLGMMPDPNTKCYVSGWGDTL--ATYPEKLLAAEVPLI 354
K++ + FN+ V+PVCLP GMM D + +C++SGWG T + L AA VPLI
Sbjct: 348 KLQ----TPLAFNDLVKPVCLPNPGMMLDLDQECWISGWGATYEKGKTSDVLNAAMVPLI 403
Query: 355 KPERCYD--FYKGRLTERMQCAGYEAGGIDTCQGDSGGPLVCKVNGIYTIFGATSWGNGC 528
+P +C Y +T M CAG+ G +D+CQGDSGGPLV NGI+ + G TSWG+GC
Sbjct: 404 EPSKCNSKYIYNNLITPAMICAGFLQGSVDSCQGDSGGPLVTLKNGIWWLIGDTSWGSGC 463
Query: 529 AQPRNPGVYAKIQIMLEWVKEQ 594
A+ PGVY + + +W+ +Q
Sbjct: 464 AKALRPGVYGNVTVFTDWIYQQ 485
>sp|Q5G269|NETR_PONPY Neurotrypsin precursor
Length = 877
Score = 158 bits (400), Expect = 1e-38
Identities = 77/208 (37%), Positives = 121/208 (58%), Gaps = 7/208 (3%)
Frame = +1
Query: 1 WIIGAAHCYARPKNE---YRVRTGDWDNSADNNDKYEQVFEIEELILHPNWNNANYDYDL 171
W++ AAHC+ R N Y VR GD+ +++E+ ++++++H + + DYD+
Sbjct: 672 WVLTAAHCFKRYGNSTRNYAVRVGDYHTLVP--EEFEEEVGVQQIVIHREYRPDSSDYDI 729
Query: 172 ALIKIERNDGVGIKFNNYVQPVCLPKLGMMPDPN-TKCYVSGWGDTLATYPEKLLAAEVP 348
AL++++ + +F+++V P CLP P + CY++GWGDT Y L A +P
Sbjct: 730 ALVRLQGPEEQCARFSSHVLPACLPLWRERPQKTASNCYITGWGDTGRAYSRTLQQAAIP 789
Query: 349 LIKPERCYDFYKGRLTERMQCAG--YEAGGIDTCQGDSGGPLVCKVNG-IYTIFGATSWG 519
L+ C + YKG T RM CAG +E +D+CQGDSGGPL+C+ G + ++G TSWG
Sbjct: 790 LLPKRFCEERYKGXFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWG 849
Query: 520 NGCAQPRNPGVYAKIQIMLEWVKEQTGL 603
GC +PGVY K+ + W+K T L
Sbjct: 850 YGCGVKDSPGVYTKVSAFVPWIKSVTKL 877
>sp|Q91Y47|FA11_MOUSE Coagulation factor XI precursor (Plasma thromboplastin antecedent)
(PTA) (FXI) [Contains: Coagulation factor XIa heavy
chain; Coagulation factor XIa light chain]
Length = 624
Score = 157 bits (398), Expect = 2e-38
Identities = 78/203 (38%), Positives = 120/203 (59%), Gaps = 4/203 (1%)
Frame = +1
Query: 1 WIIGAAHCYARPKNEYRVRT-GDWDNSADNNDKYEQVFEIEELILHPNWNNANYDYDLAL 177
WI+ AAHC++ + ++R G N ++ N+ F +E+I+H + A YD+AL
Sbjct: 424 WILTAAHCFSGIETPKKLRVYGGIVNQSEINEG-TAFFREQEMIIHDQYTTAESGYDIAL 482
Query: 178 IKIERNDGVGIKFNNYVQPVCLPKLGMMPDPNTKCYVSGWGDTL--ATYPEKLLAAEVPL 351
+K+E + + ++ +P+CLP G +T+C+V+GWG T L A+VPL
Sbjct: 483 LKLES----AMNYTDFQRPICLPSKGDRNAVHTECWVTGWGYTALRGEVQSTLQKAKVPL 538
Query: 352 IKPERCYDFYKG-RLTERMQCAGYEAGGIDTCQGDSGGPLVCKVNGIYTIFGATSWGNGC 528
+ E C Y+ ++T +M CAGY+ GG DTC+GDSGGPL CK NG++ + G TSWG GC
Sbjct: 539 VSNEECQTRYRRHKITNKMICAGYKEGGKDTCKGDSGGPLSCKYNGVWHLVGITSWGEGC 598
Query: 529 AQPRNPGVYAKIQIMLEWVKEQT 597
Q PGVY + ++W+ E+T
Sbjct: 599 GQKERPGVYTNVAKYVDWILEKT 621
>sp|Q5G271|NETR_PANTR Neurotrypsin precursor
Length = 875
Score = 157 bits (398), Expect = 2e-38
Identities = 77/208 (37%), Positives = 120/208 (57%), Gaps = 7/208 (3%)
Frame = +1
Query: 1 WIIGAAHCYARPKNE---YRVRTGDWDNSADNNDKYEQVFEIEELILHPNWNNANYDYDL 171
W++ AAHC+ R N Y VR GD+ +++E+ ++++++H + DYD+
Sbjct: 670 WVLTAAHCFKRYGNSTRSYAVRVGDYHTLVP--EEFEEEIGVQQIVIHREYRPDRSDYDI 727
Query: 172 ALIKIERNDGVGIKFNNYVQPVCLPKLGMMPDPN-TKCYVSGWGDTLATYPEKLLAAEVP 348
AL++++ + +F+++V P CLP P + CY++GWGDT Y L A +P
Sbjct: 728 ALVRLQGPEEQCARFSSHVLPACLPLWRERPQKTASNCYITGWGDTGRAYSRTLQQAAIP 787
Query: 349 LIKPERCYDFYKGRLTERMQCAG--YEAGGIDTCQGDSGGPLVCKVNG-IYTIFGATSWG 519
L+ C + YK R T RM CAG +E +D+CQGDSGGPL+C+ G + ++G TSWG
Sbjct: 788 LLPKRFCEERYKRRFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWG 847
Query: 520 NGCAQPRNPGVYAKIQIMLEWVKEQTGL 603
GC +PGVY K+ + W+K T L
Sbjct: 848 YGCGVKDSPGVYTKVSAFVPWIKSVTKL 875
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,815,337
Number of Sequences: 369166
Number of extensions: 1808827
Number of successful extensions: 5418
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4230
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4383
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 5636246860
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)