Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_020_E12
(864 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9NRR5|UBQL4_HUMAN Ubiquilin-4 (Ataxin-1 ubiquitin-like ... 89 2e-17
sp|Q99NB8|UBQL4_MOUSE Ubiquilin-4 (Ataxin-1 ubiquitin-like ... 87 6e-17
sp|Q8R317|UBQL1_MOUSE Ubiquilin-1 (Protein linking IAP with... 64 5e-10
sp|Q9UHD9|UBQL2_HUMAN Ubiquilin-2 (Protein linking IAP with... 64 5e-10
sp|Q9UMX0|UBQL1_HUMAN Ubiquilin-1 (Protein linking IAP with... 64 7e-10
sp|Q9JJP9|UBQL1_RAT Ubiquilin-1 (Protein linking IAP with c... 64 7e-10
sp|Q9QZM0|UBQL2_MOUSE Ubiquilin-2 (Protein linking IAP with... 61 5e-09
sp|Q10169|DPH1_SCHPO Deubiquitination-protection protein dph1 52 3e-06
sp|Q9H347|UBQL3_HUMAN Ubiquilin-3 49 1e-05
sp|Q8C5U9|UBQL3_MOUSE Ubiquilin-3 44 8e-04
>sp|Q9NRR5|UBQL4_HUMAN Ubiquilin-4 (Ataxin-1 ubiquitin-like interacting protein A1U)
Length = 601
Score = 89.0 bits (219), Expect = 2e-17
Identities = 65/208 (31%), Positives = 88/208 (42%), Gaps = 1/208 (0%)
Frame = +2
Query: 137 AENLHNLLGSFNDPRIQSLIETLRSNPQFTEMAIANSPA-AANPQLQEQLRNSMPQVLQA 313
+EN + + P ++S+++TL NP F + N P A NPQLQEQLR +P LQ
Sbjct: 391 SENPQLMQNVISAPYMRSMMQTLAQNPDFAAQMMVNVPLFAGNPQLQEQLRLQLPVFLQQ 450
Query: 314 FERPEVRNALTNPRVLQAIFXXXXXXXXXXXEAPHLXXXXXXXXXXXXXXXXXXXXXXXX 493
+ PE + LTNPR +QA+ EAP L
Sbjct: 451 MQNPESLSILTNPRAMQALLQIQQGLQTLQTEAPGLVPSLGSFGISRTPAPSAGSNAGST 510
Query: 494 XGGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNPGAGLNSAVGGNPEQLYSSELETMAQ 673
G+G NS V PE + +LE +
Sbjct: 511 PEAPTSSPATPATSSPTGASSAQQQLMQQMIQLLAGSG-NSQV-QTPEVRFQQQLEQLNS 568
Query: 674 MGFPNRQANLRALIETFGDVNAAVNRIL 757
MGF NR+ANL+ALI T GD+NAA+ R+L
Sbjct: 569 MGFINREANLQALIATGGDINAAIERLL 596
>sp|Q99NB8|UBQL4_MOUSE Ubiquilin-4 (Ataxin-1 ubiquitin-like interacting protein A1U)
Length = 596
Score = 87.0 bits (214), Expect = 6e-17
Identities = 64/208 (30%), Positives = 88/208 (42%), Gaps = 1/208 (0%)
Frame = +2
Query: 137 AENLHNLLGSFNDPRIQSLIETLRSNPQFTEMAIANSPA-AANPQLQEQLRNSMPQVLQA 313
+EN + + P ++++++TL NP F + N P A NPQLQEQLR +P LQ
Sbjct: 386 SENPQLMQNVISAPYMRTMMQTLAQNPDFAAQMMVNVPLFAGNPQLQEQLRLQLPVFLQQ 445
Query: 314 FERPEVRNALTNPRVLQAIFXXXXXXXXXXXEAPHLXXXXXXXXXXXXXXXXXXXXXXXX 493
+ PE + LTNPR +QA+ EAP L
Sbjct: 446 MQNPESLSILTNPRAMQALLQIQQGLQTLQTEAPGLVPSLGSFGTPRTSVPLAGSNSGSS 505
Query: 494 XGGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNPGAGLNSAVGGNPEQLYSSELETMAQ 673
G+G NS V PE + +LE +
Sbjct: 506 AEAPTSSPGVPATSPPSAGSNAQQQLMQQMIQLLSGSG-NSQV-PMPEVRFQQQLEQLNS 563
Query: 674 MGFPNRQANLRALIETFGDVNAAVNRIL 757
MGF NR+ANL+ALI T GD+NAA+ R+L
Sbjct: 564 MGFINREANLQALIATGGDINAAIERLL 591
>sp|Q8R317|UBQL1_MOUSE Ubiquilin-1 (Protein linking IAP with cytoskeleton-1) (PLIC-1)
Length = 582
Score = 63.9 bits (154), Expect = 5e-10
Identities = 32/95 (33%), Positives = 51/95 (53%), Gaps = 1/95 (1%)
Frame = +2
Query: 140 ENLHNLLGSFNDPRIQSLIETLRSNPQFTEMAIANSPA-AANPQLQEQLRNSMPQVLQAF 316
EN + + P ++S++++L NP + N+P A NPQLQEQ+R +P LQ
Sbjct: 380 ENPQLMQNMLSAPYMRSMLQSLSQNPDLAAQMMLNNPLFAGNPQLQEQMRQQLPTFLQQM 439
Query: 317 ERPEVRNALTNPRVLQAIFXXXXXXXXXXXEAPHL 421
+ P+ +A++NPR +QA+ EAP L
Sbjct: 440 QNPDTLSAMSNPRAMQALLQIQQGLQTLATEAPGL 474
Score = 53.5 bits (127), Expect = 7e-07
Identities = 27/56 (48%), Positives = 39/56 (69%)
Frame = +2
Query: 602 AGLNSAVGGNPEQLYSSELETMAQMGFPNRQANLRALIETFGDVNAAVNRILQFDP 769
AG+N + +PE + +LE ++ MGF NR+ANL+ALI T GD+NAA+ R+L P
Sbjct: 527 AGVNPQLQ-SPEVRFQQQLEQLSAMGFLNREANLQALIATGGDINAAIERLLGSQP 581
Score = 33.9 bits (76), Expect = 0.60
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
Frame = +2
Query: 158 LGSFNDPRIQSLIET-LRSNPQFTEMAIAN---SPAAANPQLQEQLRNSMPQVLQAFER- 322
L + N +QS ++ L SNP+ + N +NP L QL + PQ+ Q +R
Sbjct: 154 LNTTNFSELQSQMQRQLLSNPEMMVQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRN 213
Query: 323 PEVRNALTNPRVLQ 364
PE+ + L NP +++
Sbjct: 214 PEISHMLNNPDIMR 227
>sp|Q9UHD9|UBQL2_HUMAN Ubiquilin-2 (Protein linking IAP with cytoskeleton-2) (PLIC-2)
(hPLIC-2) (Ubiquitin-like product Chap1/Dsk2) (DSK2
homolog) (Chap1)
Length = 624
Score = 63.9 bits (154), Expect = 5e-10
Identities = 33/95 (34%), Positives = 51/95 (53%), Gaps = 1/95 (1%)
Frame = +2
Query: 140 ENLHNLLGSFNDPRIQSLIETLRSNPQFTEMAIANSPA-AANPQLQEQLRNSMPQVLQAF 316
EN + + P ++S++++L NP + NSP ANPQLQEQ+R +P LQ
Sbjct: 378 ENPQLIQNMLSAPYMRSMMQSLSQNPDLAAQMMLNSPLFTANPQLQEQMRPQLPAFLQQM 437
Query: 317 ERPEVRNALTNPRVLQAIFXXXXXXXXXXXEAPHL 421
+ P+ +A++NPR +QA+ EAP L
Sbjct: 438 QNPDTLSAMSNPRAMQALMQIQQGLQTLATEAPGL 472
Score = 56.2 bits (134), Expect = 1e-07
Identities = 28/56 (50%), Positives = 37/56 (66%)
Frame = +2
Query: 602 AGLNSAVGGNPEQLYSSELETMAQMGFPNRQANLRALIETFGDVNAAVNRILQFDP 769
AG N+ NPE + +LE + MGF NR+ANL+ALI T GD+NAA+ R+L P
Sbjct: 568 AGANAPQLPNPEVRFQQQLEQLNAMGFLNREANLQALIATGGDINAAIERLLGSQP 623
Score = 32.0 bits (71), Expect = 2.3
Identities = 22/74 (29%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
Frame = +2
Query: 158 LGSFNDPRIQSLIET-LRSNPQFTEMAIAN---SPAAANPQLQEQLRNSMPQVLQAFER- 322
L S N +QS ++ L ++P+ + N +NP L QL + PQ+ Q +R
Sbjct: 159 LSSTNFSELQSQMQQQLMASPEMMIQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRN 218
Query: 323 PEVRNALTNPRVLQ 364
PE+ + L NP +++
Sbjct: 219 PEISHLLNNPDIMR 232
>sp|Q9UMX0|UBQL1_HUMAN Ubiquilin-1 (Protein linking IAP with cytoskeleton-1) (PLIC-1)
(hPLIC-1)
Length = 589
Score = 63.5 bits (153), Expect = 7e-10
Identities = 32/95 (33%), Positives = 51/95 (53%), Gaps = 1/95 (1%)
Frame = +2
Query: 140 ENLHNLLGSFNDPRIQSLIETLRSNPQFTEMAIANSPA-AANPQLQEQLRNSMPQVLQAF 316
EN + + P ++S++++L NP + N+P A NPQLQEQ+R +P LQ
Sbjct: 386 ENPQLMQNMLSAPYMRSMMQSLSQNPDLAAQMMLNNPLFAGNPQLQEQMRQQLPTFLQQM 445
Query: 317 ERPEVRNALTNPRVLQAIFXXXXXXXXXXXEAPHL 421
+ P+ +A++NPR +QA+ EAP L
Sbjct: 446 QNPDTLSAMSNPRAMQALLQIQQGLQTLATEAPGL 480
Score = 55.5 bits (132), Expect = 2e-07
Identities = 28/56 (50%), Positives = 39/56 (69%)
Frame = +2
Query: 602 AGLNSAVGGNPEQLYSSELETMAQMGFPNRQANLRALIETFGDVNAAVNRILQFDP 769
AG+N + NPE + +LE ++ MGF NR+ANL+ALI T GD+NAA+ R+L P
Sbjct: 534 AGVNPQLQ-NPEVRFQQQLEQLSAMGFLNREANLQALIATGGDINAAIERLLGSQP 588
Score = 33.9 bits (76), Expect = 0.60
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
Frame = +2
Query: 158 LGSFNDPRIQSLIET-LRSNPQFTEMAIAN---SPAAANPQLQEQLRNSMPQVLQAFER- 322
L + N +QS ++ L SNP+ + N +NP L QL + PQ+ Q +R
Sbjct: 163 LNTTNFSELQSQMQRQLLSNPEMMVQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRN 222
Query: 323 PEVRNALTNPRVLQ 364
PE+ + L NP +++
Sbjct: 223 PEISHMLNNPDIMR 236
>sp|Q9JJP9|UBQL1_RAT Ubiquilin-1 (Protein linking IAP with cytoskeleton-1) (PLIC-1)
Length = 582
Score = 63.5 bits (153), Expect = 7e-10
Identities = 32/95 (33%), Positives = 51/95 (53%), Gaps = 1/95 (1%)
Frame = +2
Query: 140 ENLHNLLGSFNDPRIQSLIETLRSNPQFTEMAIANSPA-AANPQLQEQLRNSMPQVLQAF 316
EN + + P ++S++++L NP + N+P A NPQLQEQ+R +P LQ
Sbjct: 380 ENPQLMQNMLSAPYMRSMMQSLSQNPDLAAQMMLNNPLFAGNPQLQEQMRQQLPTFLQQM 439
Query: 317 ERPEVRNALTNPRVLQAIFXXXXXXXXXXXEAPHL 421
+ P+ +A++NPR +QA+ EAP L
Sbjct: 440 QNPDTLSAMSNPRAMQALLQIQQGLQTLATEAPGL 474
Score = 53.5 bits (127), Expect = 7e-07
Identities = 27/56 (48%), Positives = 39/56 (69%)
Frame = +2
Query: 602 AGLNSAVGGNPEQLYSSELETMAQMGFPNRQANLRALIETFGDVNAAVNRILQFDP 769
AG+N + +PE + +LE ++ MGF NR+ANL+ALI T GD+NAA+ R+L P
Sbjct: 527 AGVNPQLQ-SPEVRFQQQLEQLSAMGFLNREANLQALIATGGDINAAIERLLGSQP 581
Score = 34.7 bits (78), Expect = 0.35
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
Frame = +2
Query: 158 LGSFNDPRIQSLIET-LRSNPQFTEMAIAN---SPAAANPQLQEQLRNSMPQVLQAFER- 322
L + N +QS ++ L SNP+ + N +NP L QL + PQ+ Q +R
Sbjct: 154 LNTTNFSELQSQMQRQLLSNPEMMVQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRN 213
Query: 323 PEVRNALTNPRVLQ 364
PE+ + L NP +++
Sbjct: 214 PEISHMLNNPNIMR 227
>sp|Q9QZM0|UBQL2_MOUSE Ubiquilin-2 (Protein linking IAP with cytoskeleton-2) (PLIC-2)
(Ubiquitin-like product Chap1/Dsk2) (DSK2 homolog)
(Chap1)
Length = 638
Score = 60.8 bits (146), Expect = 5e-09
Identities = 32/95 (33%), Positives = 50/95 (52%), Gaps = 1/95 (1%)
Frame = +2
Query: 140 ENLHNLLGSFNDPRIQSLIETLRSNPQFTEMAIANSPA-AANPQLQEQLRNSMPQVLQAF 316
EN + + P ++S++++L NP + +SP +NPQLQEQ+R +P LQ
Sbjct: 392 ENPQLIQNMLSAPYMRSMMQSLSQNPDMAAQMMLSSPLFTSNPQLQEQMRPQLPNFLQQM 451
Query: 317 ERPEVRNALTNPRVLQAIFXXXXXXXXXXXEAPHL 421
+ PE A++NPR +QA+ EAP L
Sbjct: 452 QNPETIAAMSNPRAMQALMQIQQGLQTLATEAPGL 486
Score = 53.5 bits (127), Expect = 7e-07
Identities = 25/47 (53%), Positives = 33/47 (70%)
Frame = +2
Query: 629 NPEQLYSSELETMAQMGFPNRQANLRALIETFGDVNAAVNRILQFDP 769
NPE + +LE + MGF NR+ANL+ALI T GD+NAA+ R+L P
Sbjct: 591 NPEVRFQQQLEQLNAMGFLNREANLQALIATGGDINAAIERLLGSQP 637
Score = 32.0 bits (71), Expect = 2.3
Identities = 20/69 (28%), Positives = 35/69 (50%)
Frame = +2
Query: 164 SFNDPRIQSLIETLRSNPQFTEMAIANSPAAANPQLQEQLRNSMPQVLQAFERPEVRNAL 343
SF + SL ++P FTE+ Q+Q+QL S ++Q E P V++ L
Sbjct: 156 SFGLGSLSSLSNLGLNSPNFTEL---------RNQMQQQLLASPEMMIQIMENPFVQSML 206
Query: 344 TNPRVLQAI 370
+NP +++ +
Sbjct: 207 SNPDLMRQL 215
Score = 31.2 bits (69), Expect = 3.9
Identities = 24/84 (28%), Positives = 42/84 (50%), Gaps = 4/84 (4%)
Frame = +2
Query: 125 NLPSAENLHNLLGSFNDPRIQSLIETLRSNPQFTEMAIAN---SPAAANPQLQEQLRNSM 295
+L S NL +F + R Q + + L ++P+ + N +NP L QL +
Sbjct: 161 SLSSLSNLGLNSPNFTELRNQ-MQQQLLASPEMMIQIMENPFVQSMLSNPDLMRQLIMAN 219
Query: 296 PQVLQAFER-PEVRNALTNPRVLQ 364
PQ+ Q +R PE+ + L NP +++
Sbjct: 220 PQMQQLIQRNPEISHLLNNPDIMR 243
>sp|Q10169|DPH1_SCHPO Deubiquitination-protection protein dph1
Length = 354
Score = 51.6 bits (122), Expect = 3e-06
Identities = 33/90 (36%), Positives = 48/90 (53%)
Frame = +2
Query: 95 GGNTQINIPSNLPSAENLHNLLGSFNDPRIQSLIETLRSNPQFTEMAIANSPAAANPQLQ 274
G N + +P PS E L N+L ++P +QS I + SNPQ +M I +SP
Sbjct: 130 GPNPENPVP---PSTEELANML---SNPMVQSSINEMFSNPQMLDMIINSSP-------- 175
Query: 275 EQLRNSMPQVLQAFERPEVRNALTNPRVLQ 364
LRN+ P V Q + PE R A+T+P ++
Sbjct: 176 -HLRNAPPYVRQMMQSPEFRRAMTDPDTMR 204
Score = 34.7 bits (78), Expect = 0.35
Identities = 19/64 (29%), Positives = 34/64 (53%), Gaps = 12/64 (18%)
Frame = +2
Query: 602 AGLNSAVGGN------------PEQLYSSELETMAQMGFPNRQANLRALIETFGDVNAAV 745
AGL + +GG PE+ Y+ +L + +MGF + + N++AL + G+V A+
Sbjct: 288 AGLGAGLGGAASPPAPAQDTRPPEERYAEQLSQLNEMGFVDFERNVQALRRSGGNVQGAI 347
Query: 746 NRIL 757
+L
Sbjct: 348 ESLL 351
>sp|Q9H347|UBQL3_HUMAN Ubiquilin-3
Length = 655
Score = 49.3 bits (116), Expect = 1e-05
Identities = 27/56 (48%), Positives = 36/56 (64%), Gaps = 5/56 (8%)
Frame = +2
Query: 608 LNSAVGGNPEQL-----YSSELETMAQMGFPNRQANLRALIETFGDVNAAVNRILQ 760
L V NP+QL + +LE + MGF NR+ANL+ALI T GDV+AAV ++ Q
Sbjct: 599 LQDLVSTNPQQLQPEAHFQVQLEQLRSMGFLNREANLQALIATGGDVDAAVEKLRQ 654
>sp|Q8C5U9|UBQL3_MOUSE Ubiquilin-3
Length = 658
Score = 43.5 bits (101), Expect = 8e-04
Identities = 24/54 (44%), Positives = 34/54 (62%), Gaps = 5/54 (9%)
Frame = +2
Query: 608 LNSAVGGNPEQL-----YSSELETMAQMGFPNRQANLRALIETFGDVNAAVNRI 754
L + NP+QL + +LE + MGF N +ANL+ALI T GDV+AAV ++
Sbjct: 602 LQALASTNPQQLQLEAHFRVQLEQLRAMGFLNLEANLQALIATEGDVDAAVEKL 655
Score = 30.0 bits (66), Expect = 8.7
Identities = 15/53 (28%), Positives = 26/53 (49%)
Frame = +2
Query: 263 PQLQEQLRNSMPQVLQAFERPEVRNALTNPRVLQAIFXXXXXXXXXXXEAPHL 421
P++Q ++ +P +L ++ A+ NPRV+QA+ EAP L
Sbjct: 498 PRIQNEIHQQLPLLLH------LQTAMANPRVMQALLQIEQGLQILATEAPRL 544
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,719,846
Number of Sequences: 369166
Number of extensions: 1620764
Number of successful extensions: 3721
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3587
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3710
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8582957970
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)