Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_020_D16
(851 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P50990|TCPQ_HUMAN T-complex protein 1, theta subunit (TC... 303 3e-82
sp|P42932|TCPQ_MOUSE T-complex protein 1, theta subunit (TC... 298 1e-80
sp|P78921|TCPQ_SCHPO Probable T-complex protein 1, theta su... 250 3e-66
sp|P47079|TCPQ_YEAST T-complex protein 1, theta subunit (TC... 219 1e-56
sp|P47828|TCPQ_CANAL T-complex protein 1, theta subunit (TC... 160 4e-39
sp|O28045|THSA_ARCFU Thermosome alpha subunit (Thermosome s... 136 6e-32
sp|O93624|THS_METTL Thermosome subunit (Chaperonin subunit) 135 2e-31
sp|Q58405|THS_METJA Thermosome subunit (Chaperonin subunit) 129 1e-29
sp|P50016|THS_METKA Thermosome subunit (Chaperonin-like com... 127 3e-29
sp|O26885|THSB_METTH Thermosome beta subunit (Thermosome su... 127 3e-29
>sp|P50990|TCPQ_HUMAN T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
sp|Q5RAP1|TCPQ_PONPY T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
Length = 548
Score = 303 bits (777), Expect = 3e-82
Identities = 149/283 (52%), Positives = 205/283 (72%)
Frame = +1
Query: 1 AMHIPTAPGYLSMMKEGSRFYQGLEESVYRNIQACVALGQTTASTFGPQGMKKMVINHIG 180
A+H+P APG+ M+KEG++ + GLEE+VYRNIQAC L QTT + +GP GM KMVINH+
Sbjct: 2 ALHVPKAPGFAQMLKEGAKHFSGLEEAVYRNIQACKELAQTTRTAYGPNGMNKMVINHLE 61
Query: 181 KKFVTKDASTILRELEVEHPAAKLMVMXXXXXXXXSGEATNFVIILCASLLEKAEYLLKM 360
K FVT DA+TILRELEV+HPAAK++VM G+ TNFV++ +LLE AE LL++
Sbjct: 62 KLFVTNDAATILRELEVQHPAAKMIVMASHMQEQEVGDGTNFVLVFAGALLELAEELLRI 121
Query: 361 GLSVPDVTEGFEIAAKHSLEILKDLVIGKVEDLREKEMIKKIVGTAVNSKIFGEESHISD 540
GLSV +V EG+EIA + + EIL +LV ++LR+ + + ++ T++ SK +G E ++
Sbjct: 122 GLSVSEVIEGYEIACRKAHEILPNLVCCSAKNLRDIDEVSSLLRTSIMSKQYGNEVFLAK 181
Query: 541 LVVDACIRALPTSSFFNVDNIRVVKILGSGTNASKVFNGMVFVREAQSVIKECKAAKVVV 720
L+ AC+ P S FNVDNIRV KILGSG ++S V +GMVF +E + + K AK+ V
Sbjct: 182 LIAQACVSIFPDSGHFNVDNIRVCKILGSGISSSSVLHGMVFKKETEGDVTSVKDAKIAV 241
Query: 721 FSCPFDQLQTETKGTVLINTAKELMDFSRGEEDQMEERVREIA 849
+SCPFD + TETKGTVLI TA+ELM+FS+GEE+ M+ +V+ IA
Sbjct: 242 YSCPFDGMITETKGTVLIKTAEELMNFSKGEENLMDAQVKAIA 284
>sp|P42932|TCPQ_MOUSE T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
Length = 548
Score = 298 bits (764), Expect = 1e-80
Identities = 147/283 (51%), Positives = 203/283 (71%)
Frame = +1
Query: 1 AMHIPTAPGYLSMMKEGSRFYQGLEESVYRNIQACVALGQTTASTFGPQGMKKMVINHIG 180
A+H+P APG+ M+K+G++ + GLEE+VYRNIQAC L QTT + +GP GM KMVIN +
Sbjct: 2 ALHVPKAPGFAQMLKDGAKHFSGLEEAVYRNIQACKELAQTTRTAYGPNGMNKMVINRLE 61
Query: 181 KKFVTKDASTILRELEVEHPAAKLMVMXXXXXXXXSGEATNFVIILCASLLEKAEYLLKM 360
K FVT DA+TILRELEV+HPAAK++VM G+ TNFV++ +LLE AE LL++
Sbjct: 62 KLFVTNDAATILRELEVQHPAAKMIVMASHMQEQEVGDGTNFVLVFAGALLELAEELLRI 121
Query: 361 GLSVPDVTEGFEIAAKHSLEILKDLVIGKVEDLREKEMIKKIVGTAVNSKIFGEESHISD 540
GLSV +V G+EIA K + EIL +LV ++LR+ + + ++ T++ SK +G E+ ++
Sbjct: 122 GLSVSEVISGYEIACKKAHEILPELVCCSAKNLRDVDEVSSLLRTSIMSKQYGSETFLAK 181
Query: 541 LVVDACIRALPTSSFFNVDNIRVVKILGSGTNASKVFNGMVFVREAQSVIKECKAAKVVV 720
L+ AC+ P S FNVDNIRV KILGSG +S V +GMVF +E + + K AK+ V
Sbjct: 182 LIAQACVSIFPDSGNFNVDNIRVCKILGSGIYSSSVLHGMVFKKETEGDVTSVKDAKIAV 241
Query: 721 FSCPFDQLQTETKGTVLINTAKELMDFSRGEEDQMEERVREIA 849
+SCPFD + TETKGTVLI TA+ELM+FS+GEE+ M+ +V+ IA
Sbjct: 242 YSCPFDGMITETKGTVLIKTAEELMNFSKGEENLMDAQVKAIA 284
>sp|P78921|TCPQ_SCHPO Probable T-complex protein 1, theta subunit (TCP-1-theta)
(CCT-theta)
Length = 546
Score = 250 bits (639), Expect = 3e-66
Identities = 127/283 (44%), Positives = 188/283 (66%), Gaps = 1/283 (0%)
Frame = +1
Query: 1 AMHIPTAPGYLSMMKEGSRFYQGLEESVYRNIQACVALGQTTASTFGPQGMKKMVINHIG 180
A+ +P A G + +EG R QG+E++V RN A L + T ++ GP G K+V+NH+
Sbjct: 2 ALRVPKASGP-QLFREGYRIMQGVEDAVIRNCNAIRELSEITRTSLGPNGKNKIVVNHLQ 60
Query: 181 KKFVTKDASTILRELEVEHPAAKLMVMXXXXXXXXSGEATNFVIILCASLLEKAEYLLKM 360
+ F+T DA+TI+RELEV HPAAKL+V G+A NFV++ LL KAE +++M
Sbjct: 61 QTFLTNDAATIIRELEVIHPAAKLVVDATQQQENELGDAANFVVVFTGELLAKAENMIRM 120
Query: 361 GLSVPDVTEGFEIAAKHSLEILKDLVIGKVEDLREKEMIKKIVGTAVNSKIFGEESHISD 540
GL+ ++ +G+E+A H++E+L+++ K+E + ++ + K + T ++SK +G E +SD
Sbjct: 121 GLTPLEIAKGYEMALSHTMEVLEEICADKIETVESEKELIKAIRTCISSKQYGNEDFLSD 180
Query: 541 LVVDACIRALPTS-SFFNVDNIRVVKILGSGTNASKVFNGMVFVREAQSVIKECKAAKVV 717
LV A + LP S FNVDNIRVVKI+GS S+V GMVF RE + + K AKV
Sbjct: 181 LVAKAILTVLPKDPSKFNVDNIRVVKIMGSSLYNSQVVKGMVFprePEGTVTRSKEAKVA 240
Query: 718 VFSCPFDQLQTETKGTVLINTAKELMDFSRGEEDQMEERVREI 846
VFSCP D QTETKGTVL++ A+E++DFS+GEE+ +E ++EI
Sbjct: 241 VFSCPLDISQTETKGTVLLHNAQEMLDFSKGEENLIESHIKEI 283
>sp|P47079|TCPQ_YEAST T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
Length = 568
Score = 219 bits (557), Expect = 1e-56
Identities = 114/292 (39%), Positives = 180/292 (61%), Gaps = 9/292 (3%)
Frame = +1
Query: 1 AMHIPTAPGYLSMMKEGSRFYQGLEESVYRNIQACVALGQTTASTFGPQGMKKMVINHIG 180
++ +P P + K+G Y + + ++I A L Q ++ GP G K+++NH+G
Sbjct: 2 SLRLPQNPN-AGLFKQGYNSYSNADGQIIKSIAAIRELHQMCLTSMGPCGRNKIIVNHLG 60
Query: 181 KKFVTKDASTILRELEVEHPAAKLMVMXXXXXXXXSGEATNFVIILCASLLEKAEYLLKM 360
K +T DA+T+LREL++ HPA K++VM G+ TN V+IL LL +E L+ M
Sbjct: 61 KIIITNDAATMLRELDIVHPAVKVLVMATEQQKIDMGDGTNLVMILAGELLNVSEKLISM 120
Query: 361 GLSVPDVTEGFEIAAKHSLEILKDLVIGKVEDLREKEMIKKIVGTAVNSKIFGEESHISD 540
GLS ++ +G+ +A K +L+ L ++V+G++ D +K + K++ ++SK +G E +S+
Sbjct: 121 GLSAVEIIQGYNMARKFTLKELDEMVVGEITDKNDKNELLKMIKPVISSKKYGSEDILSE 180
Query: 541 LVVDACIRALPTSS------FFNVDNIRVVKILGSGTNASKVFNGMVFVREAQSVIK--- 693
LV +A LP + +FNVD+IRVVKI+G + S V GMVF RE + +K
Sbjct: 181 LVSEAVSHVLPVAQQAGEIPYFNVDSIRVVKIMGGSLSNSTVIKGMVFNREPEGHVKSLS 240
Query: 694 ECKAAKVVVFSCPFDQLQTETKGTVLINTAKELMDFSRGEEDQMEERVREIA 849
E K KV VF+CP D TETKGTVL++ A+E++DFS+GEE Q++ ++EIA
Sbjct: 241 EDKKHKVAVFTCPLDIANTETKGTVLLHNAQEMLDFSKGEEKQIDAMMKEIA 292
>sp|P47828|TCPQ_CANAL T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
Length = 540
Score = 160 bits (405), Expect = 4e-39
Identities = 86/231 (37%), Positives = 137/231 (59%)
Frame = +1
Query: 1 AMHIPTAPGYLSMMKEGSRFYQGLEESVYRNIQACVALGQTTASTFGPQGMKKMVINHIG 180
++ +P AP + K+G + + ++ RN++A + ++ GP G K+++N +G
Sbjct: 2 SLKLPQAPNS-GLFKQGYSSFSNADGAIIRNVEAVREIASILLTSMGPSGRNKIIVNKLG 60
Query: 181 KKFVTKDASTILRELEVEHPAAKLMVMXXXXXXXXSGEATNFVIILCASLLEKAEYLLKM 360
KKF+T DA+T+L ELE+ HP K+++ G+ TN VIIL L AE LL +
Sbjct: 61 KKFITNDAATMLNELEIVHPVVKILIQASKQQEFEMGDNTNLVIILAGEFLNVAEKLLTL 120
Query: 361 GLSVPDVTEGFEIAAKHSLEILKDLVIGKVEDLREKEMIKKIVGTAVNSKIFGEESHISD 540
GL+V ++ +GF +A K ++ L +LV+ KVE E +++ K V + +K +G E I+
Sbjct: 121 GLNVSEIIQGFNLANKFVMKTLDELVVEKVESF-ETDLL-KAVKPVIAAKQYGVEDTIAK 178
Query: 541 LVVDACIRALPTSSFFNVDNIRVVKILGSGTNASKVFNGMVFVREAQSVIK 693
LVVDA + S FNVDNIRVVK++G+ + S+V GMVF RE + +K
Sbjct: 179 LVVDAVALVMKNGS-FNVDNIRVVKVMGASLSQSQVVKGMVFprePEGTVK 228
>sp|O28045|THSA_ARCFU Thermosome alpha subunit (Thermosome subunit 1) (Chaperonin alpha
subunit)
Length = 545
Score = 136 bits (343), Expect = 6e-32
Identities = 89/277 (32%), Positives = 145/277 (52%), Gaps = 6/277 (2%)
Frame = +1
Query: 37 MMKEGSRFYQGLEESVYRNIQACVALGQTTASTFGPQGMKKMVINHIGKKFVTKDASTIL 216
++KEG++ G ++ NI A + + ST GP+GM KM+++ +G +T D TIL
Sbjct: 11 ILKEGTQRTVG-RDAQRMNIMAARVIAEAVKSTLGPKGMDKMLVDSLGDVVITNDGVTIL 69
Query: 217 RELEVEHPAAKLMVMXXXXXXXXSGEATNFVIILCASLLEKAEYLLKMGLSVPDVTEGFE 396
+E++VEHPAAK+++ G+ T ++L LL+KAE LL + + G+
Sbjct: 70 KEMDVEHPAAKMIIEVAKTQDNEVGDGTTTAVVLAGELLKKAEELLDQDIHPTVIARGYR 129
Query: 397 IAAKHSLEILKDLVIGKVEDLREKEMIKKIVGTAVNSKIFGEE-SHISDLVVDACIR-AL 570
+AA ++EIL+ + + D+ ++E +KKI TA+ K H+S LVV+A R A
Sbjct: 130 MAANKAVEILESIAMD--IDVEDEETLKKIAATAITGKHSEYALDHLSSLVVEAVKRVAE 187
Query: 571 PTSSFFNV--DNIRVVKILGSGTNASKVFNGMVFVREA--QSVIKECKAAKVVVFSCPFD 738
+ V DNI++ K G +K+ NG+V +E + K K AK+ V +
Sbjct: 188 KVDDRYKVDEDNIKLEKRQGGSVADTKLVNGIVIDKEVVHPGMPKRVKNAKIAVLKAALE 247
Query: 739 QLQTETKGTVLINTAKELMDFSRGEEDQMEERVREIA 849
+TET + I +LM F EE ++E V +A
Sbjct: 248 VKETETDAEIRITDPDQLMKFIEQEEKMLKEMVDRLA 284
>sp|O93624|THS_METTL Thermosome subunit (Chaperonin subunit)
Length = 544
Score = 135 bits (339), Expect = 2e-31
Identities = 79/257 (30%), Positives = 142/257 (55%), Gaps = 5/257 (1%)
Frame = +1
Query: 91 NIQACVALGQTTASTFGPQGMKKMVINHIGKKFVTKDASTILRELEVEHPAAKLMVMXXX 270
NI A +G+T ST GP+GM KM+++ +G VT D TIL+E+ VEHPAAK+++
Sbjct: 26 NILAGRIIGETVRSTLGPKGMDKMLVDDLGDIVVTNDGVTILKEMSVEHPAAKMLIEVAK 85
Query: 271 XXXXXSGEATNFVIILCASLLEKAEYLLKMGLSVPDVTEGFEIAAKHSLEILKDLVIGKV 450
G+ T +++ LL KAE LL + V +G+++A + + E+LK++ +
Sbjct: 86 TQEKEVGDGTTTAVVIAGELLRKAEELLDQNVHPTIVIKGYQLAVQKAQEVLKEIAMDVK 145
Query: 451 EDLREKEMIKKIVGTAVNSKIFGEE---SHISDLVVDACIRALPTSSFFNVDNIRVVKIL 621
D +KE++ KI T++ K G E + +++V+A + S + D I++ K
Sbjct: 146 AD--DKEILHKIAMTSITGK--GAEKAKEKLGEMIVEAVTAVVDESGKVDKDLIKIEKKE 201
Query: 622 GSGTNASKVFNGMVFVREAQS--VIKECKAAKVVVFSCPFDQLQTETKGTVLINTAKELM 795
G+ + +++ NG++ +E S + K+ + AK+ + +CP + +TET + I +LM
Sbjct: 202 GASVDETELINGVLIDKERVSPQMPKKIENAKIALLNCPIEVKETETDAEIRITDPTKLM 261
Query: 796 DFSRGEEDQMEERVREI 846
+F EE +++ V I
Sbjct: 262 EFIEQEEKMLKDMVDTI 278
>sp|Q58405|THS_METJA Thermosome subunit (Chaperonin subunit)
Length = 542
Score = 129 bits (324), Expect = 1e-29
Identities = 84/260 (32%), Positives = 139/260 (53%), Gaps = 7/260 (2%)
Frame = +1
Query: 91 NIQACVALGQTTASTFGPQGMKKMVINHIGKKFVTKDASTILRELEVEHPAAKLMVMXXX 270
NI A + +T +T GP+GM KM+++ +G VT D TIL+E+ VEHPAAK+++
Sbjct: 27 NILAGRIIAETVRTTLGPKGMDKMLVDELGDIVVTNDGVTILKEMSVEHPAAKMLIEVAK 86
Query: 271 XXXXXSGEATNFVIILCASLLEKAEYLLKMGLSVPDVTEGFEIAAKHSLEILKDLVIGKV 450
G+ T +++ LL KAE LL + + G+E+A ++E LK I K
Sbjct: 87 TQEKEVGDGTTTAVVIAGELLRKAEELLDQNIHPSVIINGYEMARNKAVEELKS--IAKE 144
Query: 451 EDLREKEMIKKIVGTAVNSKIFGEE---SHISDLVVDACIRALPTSSFFNVDN--IRVVK 615
+ EM+KKI T++ K G E ++++VV+A +RA+ VD I+V K
Sbjct: 145 VKPEDTEMLKKIAMTSITGK--GAEKAREQLAEIVVEA-VRAVVDEETGKVDKDLIKVEK 201
Query: 616 ILGSGTNASKVFNGMVFVREA--QSVIKECKAAKVVVFSCPFDQLQTETKGTVLINTAKE 789
G+ +K+ G+V +E + K+ + AK+ + +CP + +TET + I +
Sbjct: 202 KEGAPIEETKLIRGVVIDKERVNPQMPKKVENAKIALLNCPIEVKETETDAEIRITDPAK 261
Query: 790 LMDFSRGEEDQMEERVREIA 849
LM+F EE +++ V +IA
Sbjct: 262 LMEFIEQEEKMIKDMVEKIA 281
>sp|P50016|THS_METKA Thermosome subunit (Chaperonin-like complex) (CLIC)
Length = 545
Score = 127 bits (320), Expect = 3e-29
Identities = 82/277 (29%), Positives = 144/277 (51%), Gaps = 6/277 (2%)
Frame = +1
Query: 37 MMKEGSRFYQGLEESVYRNIQACVALGQTTASTFGPQGMKKMVINHIGKKFVTKDASTIL 216
++ EG + + G ++ NI A + +T +T GP GM KM+++ +G VT D TIL
Sbjct: 13 ILPEGYQRFVG-RDAQRMNIMAARVVAETVRTTLGPMGMDKMLVDEMGDVVVTNDGVTIL 71
Query: 217 RELEVEHPAAKLMVMXXXXXXXXSGEATNFVIILCASLLEKAEYLLKMGLSVPDVTEGFE 396
E+++EHPAAK++V G+ T ++L LL KAE LL+ + + G+
Sbjct: 72 EEMDIEHPAAKMVVEVAKTQEDEVGDGTTTAVVLAGELLHKAEDLLQQDIHPTVIARGYR 131
Query: 397 IAAKHSLEILKDLVIGKVEDLREKEMIKKIVGTAVNSK-IFGEESHISDLVVDACIRALP 573
+A + + EIL++ I + D ++E +KKI TA+ K + ++++LVV A +
Sbjct: 132 MAVEKAEEILEE--IAEEIDPDDEETLKKIAKTAMTGKGVEKARDYLAELVVKAVKQVAE 189
Query: 574 TSS---FFNVDNIRVVKILGSGTNASKVFNGMVFVREA--QSVIKECKAAKVVVFSCPFD 738
+ D+I++ K G G +++ GMV +E + + + AK+ + +CP +
Sbjct: 190 EEDGEIVIDTDHIKLEKKEGGGLEDTELVKGMVIDKERVHPGMPRRVENAKIALLNCPIE 249
Query: 739 QLQTETKGTVLINTAKELMDFSRGEEDQMEERVREIA 849
+TET + I ++L F EE + E V +IA
Sbjct: 250 VKETETDAEIRITDPEQLQAFIEEEERMLSEMVDKIA 286
>sp|O26885|THSB_METTH Thermosome beta subunit (Thermosome subunit 2) (Chaperonin beta
subunit)
Length = 538
Score = 127 bits (320), Expect = 3e-29
Identities = 81/275 (29%), Positives = 145/275 (52%), Gaps = 5/275 (1%)
Frame = +1
Query: 37 MMKEGSRFYQGLEESVYRNIQACVALGQTTASTFGPQGMKKMVINHIGKKFVTKDASTIL 216
++ EG+ Y G ++ NI A L +T +T GP+GM KM+++ +G VT D TIL
Sbjct: 10 VLPEGTSRYLG-RDAQRMNILAGKILAETVRTTLGPKGMDKMLVDSLGDIVVTNDGVTIL 68
Query: 217 RELEVEHPAAKLMVMXXXXXXXXSGEATNFVIILCASLLEKAEYLLKMGLSVPDVTEGFE 396
+E+++EHPAAK++V G+ T +I+ LL+KAE LL+M + + G+
Sbjct: 69 KEMDIEHPAAKMLVEVAKTQEDEVGDGTTTAVIIAGELLKKAENLLEMEIHPTIIAMGYR 128
Query: 397 IAAKHSLEILKDLVIGKVEDLREKEMIKKIVGTAVNSKIFGEE---SHISDLVVDACIRA 567
AA+ + EIL D+ I D +++ + K+ TA+ K G E +++L+VDA ++
Sbjct: 129 QAAEKAQEILDDIAI----DASDRDTLMKVAMTAMTGK--GTEKAREPLAELIVDA-VKQ 181
Query: 568 LPTSSFFNVDNIRVVKILGSGTNASKVFNGMVFVREA--QSVIKECKAAKVVVFSCPFDQ 741
+ D+I++ K G+ + S + G++ +E + K+ + AK+ + +CP +
Sbjct: 182 VEEDGEVEKDHIKIEKKEGAAVDDSTLVQGVIIDKERVHPGMPKKVENAKIALLNCPIEV 241
Query: 742 LQTETKGTVLINTAKELMDFSRGEEDQMEERVREI 846
+TE + I ++ F EE + + V I
Sbjct: 242 KETEVDAEIRITDPSQMQAFIEQEEQMIRDMVNSI 276
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 84,124,481
Number of Sequences: 369166
Number of extensions: 1534306
Number of successful extensions: 4631
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4455
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4563
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8390082510
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)